Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_017031165.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017027363.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_041632635.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_017025354.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017038409.1 9 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-416476 "Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events" XP_041631661.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017032982.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017018411.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041631051.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-5218920 "GPVI-mediated activation cascade";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability" XP_017024274.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017030873.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017036696.1 3 Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism" XP_017027318.1 7 KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2 "D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis" XP_017033837.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_017024782.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_017033497.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017018970.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017031730.1 4 KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558 "Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine" XP_017021410.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017025628.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017038450.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017030713.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017017488.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_017021411.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017026496.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017018556.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017037692.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041630680.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017037675.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041632671.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017020249.1 57 Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084 "Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Degradation of DVL";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_017017982.1 9 Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection" XP_041632761.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017037925.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4570464 "Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins" XP_017024426.1 42 MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-5109;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6863;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-6883;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7654;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-5136;MetaCyc: PWY-6945;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5138;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6944;MetaCyc: PWY-7401;MetaCyc: PWY-7606 "Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fermentation to 2-methylbutanoate";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Geraniol degradation";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Caprolactam degradation";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid elongation";"2-methylpropene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"Fatty acid degradation";"Aminobenzoate degradation";"Tryptophan metabolism";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Glutaryl-coa degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Fatty acid salvage";"Lysine degradation";"Toluene degradation";"Spodoptera littoralis pheromone biosynthesis";"Androstenedione degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" XP_017034490.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017027499.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017028882.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_017028857.1 8 Reactome: R-HSA-209905;MetaCyc: PWY-6133;MetaCyc: PWY-5394;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2 "Catecholamine biosynthesis";"(S)-reticuline biosynthesis II";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Folate biosynthesis" XP_017030706.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_041630769.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017034597.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017031742.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017026014.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_017018554.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017026198.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_017023922.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_017021416.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360 "Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" XP_017037676.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017026666.1 13 KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00670+6.3.4.3;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-2161 "Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Folate transformations I";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation" XP_017034335.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_017032216.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017026385.1 9 Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-1362277;Reactome: R-HSA-68689;Reactome: R-HSA-69205 "CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"Transcription of E2F targets under negative control by DREAM complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription" XP_017036692.1 22 Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_041632806.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-381676 "Regulation of insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_017028825.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_041632105.1 42 Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749 "Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Processing of DNA double-strand break ends";"Meiotic synapsis";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"DNA methylation";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs" XP_017038561.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017029618.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols" XP_041631908.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-210991 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Basigin interactions" XP_041631312.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017027635.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017032702.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_017026047.1 5 MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154 "Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase" XP_017018262.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_041632332.1 7 Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_017018745.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017019559.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_017019185.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017029832.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017018614.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_017021621.1 4 KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22 "Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism" XP_017028889.1 56 Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154 "Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin" XP_017020099.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017016659.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041630367.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_017037592.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017038272.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017034827.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_041630761.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041630368.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_017018087.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_041631663.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017016400.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017022358.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017034796.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017029961.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_017030342.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017037701.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017038443.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_041631635.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_017024521.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017017756.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7411 "Glycerolipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)" XP_017034506.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041631890.1 56 Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport" XP_017025428.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017028629.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_017030471.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017016358.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_041631541.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017034316.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017026511.1 5 Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3 "Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism" XP_017029161.1 6 MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788 "Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling" XP_017026744.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6598 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis" XP_017017637.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017021051.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_041631626.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017031684.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041630470.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017023461.1 10 Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-9018519 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression" XP_017016739.1 8 Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Activation of RAC1";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017031608.1 13 MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5 "Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Propanoate metabolism" XP_017027542.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017027809.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017023012.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017022294.1 11 Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3000170 "Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Retinoid metabolism and transport";"Syndecan interactions" XP_017034466.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-912631 "Downstream signal transduction";"MET activates RAP1 and RAC1";"MET receptor recycling";"Regulation of signaling by CBL" XP_017034922.1 14 KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5104;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;Reactome: R-HSA-70895;MetaCyc: PWY-5057;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5076 "Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"L-valine degradation II";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"L-leucine degradation III" XP_017033874.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017034099.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends" XP_017016729.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_041631698.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017037272.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_041631649.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553 "Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs" XP_017027048.1 9 MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533 "4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis" XP_017028134.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017027701.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041630416.1 12 KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13 "Pentose phosphate pathway";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" XP_017021400.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017019629.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_041630786.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017033408.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017019640.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017036464.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017035453.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017023650.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_017036648.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_041631456.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017022741.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183 "DNA replication initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand" XP_017031736.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017031001.1 18 KEGG: 00620+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-389661;KEGG: 00010+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00280+1.8.1.4;KEGG: 00260+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00310+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00020+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403;KEGG: 00380+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-71064;MetaCyc: PWY-5084 "Pyruvate metabolism";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Glycine degradation";"Valine, leucine and isoleucine degradation";"Glycine, serine and threonine metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Lysine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Signaling by Retinoic Acid";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_017029101.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017028422.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017032811.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017022986.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017021569.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_017030634.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis" XP_017021956.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017027490.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017031538.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_017033967.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017035902.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017018225.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_017027341.1 5 MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017019057.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_017036174.1 7 Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-5578749 "tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs" XP_017028661.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_017036927.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_017036948.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017018451.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017029228.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017018361.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041631880.1 5 MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017023988.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_017016702.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017028735.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017033386.1 33 Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-168276 "Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways" XP_041633506.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017029220.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017035718.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017026728.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-190861 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Recycling pathway of L1";"Gap junction assembly" XP_017033640.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017038011.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017016761.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_017028052.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_017020584.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919 "Anchoring fibril formation";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils" XP_017028526.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_017031534.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017028186.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017017983.1 9 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_017028974.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017035436.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017026079.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_041632562.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017021483.1 7 MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282 "5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_017021073.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-68949 "Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hedgehog 'on' state";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Degradation of DVL";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin" XP_017035104.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017025715.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017016620.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017031592.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017033905.1 20 MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-735 "Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis" XP_017029767.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017036868.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_017038158.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017035481.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411 "DNA replication initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere" XP_017027028.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-427413 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression" XP_017020548.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017020968.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_041632739.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_017021326.1 12 MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4 "Sulfite oxidation III";"Sulfur metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Assimilatory sulfate reduction III";"Monobactam biosynthesis" XP_017030469.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_017020642.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017027500.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017036869.1 18 MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_017036004.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017030092.1 9 Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18 "Glutathione conjugation";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione metabolism";"Drug metabolism - cytochrome P450" XP_017024503.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017030755.2 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_017027304.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695 "Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation" XP_017028977.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017030449.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408 "Hedgehog ligand biogenesis";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_017034799.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_041631840.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041633496.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017027322.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2 "Arginine biosynthesis";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism" XP_017027412.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_017018467.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017036113.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017027920.1 33 Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-167246;Reactome: R-HSA-69656;Reactome: R-HSA-69231;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-69202;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823 "mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin D associated events in G1";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_017023857.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017028348.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_017035732.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017017012.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017029746.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_017037484.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017038326.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_017033859.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017036512.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017026199.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556 "Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport" XP_017022753.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_041631311.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017025930.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_017029017.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017025233.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017022553.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_017024527.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017030810.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-186763 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"Downstream signal transduction" XP_041632921.1 10 MetaCyc: PWY-6372;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158 "1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism" XP_017024062.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_017018547.1 10 Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497 "Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)" XP_017025774.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017035126.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017033846.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017033329.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017037074.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017021935.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017017987.1 9 KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis" XP_017029227.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" XP_017033312.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017035726.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017023163.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017033423.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017033663.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_041631025.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_017035428.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017024933.1 30 Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-917937;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-1170546;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5610783 "Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Iron uptake and transport";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Prolactin receptor signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome" XP_017027894.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017031122.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_041631622.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017034720.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017035654.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_041632234.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017027316.1 27 Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107 "Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_017033419.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017022184.1 14 MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017021308.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017030809.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442 "Downstream signal transduction";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs" XP_017034461.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024697.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017034239.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017021473.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_041632231.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017027966.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_017035419.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017036238.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation" XP_017031750.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017031318.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_017020305.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017017486.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_017029795.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5676590 "Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling" XP_017031175.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017016811.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017033758.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017037629.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041632180.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017035136.1 10 Reactome: R-HSA-3108214;Reactome: R-HSA-2559580;Reactome: R-HSA-4655427;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-3899300;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-8939243;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Oxidative Stress Induced Senescence";"SUMOylation of DNA methylation proteins";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"SUMOylation of transcription cofactors";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Protein ubiquitination" XP_017027494.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017035688.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_017017439.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041633426.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017028830.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017033548.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017033000.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017032894.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017029512.1 8 MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-7193;MetaCyc: PWY-6556 "Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II" XP_017022836.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105 "Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport" XP_017022476.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_017026776.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718 "PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes" XP_017022537.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017020481.1 32 Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" XP_041632925.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_017035211.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_017032701.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_017038379.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017019252.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017029616.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408 "Hedgehog ligand biogenesis";"Degradation of DVL";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_017032737.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017036736.1 7 MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10 "UMP biosynthesis III";"UMP biosynthesis II";"Drug metabolism - other enzymes";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Pyrimidine metabolism" XP_017027861.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154 "Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin" XP_017018890.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017035277.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017037986.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017037317.2 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017024753.1 10 KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10 "Butanoate metabolism";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies" XP_017022297.1 11 Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237 "Syndecan interactions";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2" XP_017018351.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041632810.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-5607763 "FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Regulation of insulin secretion";"DAG and IP3 signaling";"Ion homeostasis";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation" XP_017017812.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017035505.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017036771.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017023990.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017037899.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017026522.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_041631756.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_017033314.1 13 Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-5689896;Reactome: R-HSA-9646399;Reactome: R-HSA-8876725;Reactome: R-HSA-6798695;Reactome: R-HSA-532668;Reactome: R-HSA-5358346;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "HSF1 activation";"ABC-family proteins mediated transport";"Ovarian tumor domain proteases";"Aggrephagy";"Protein methylation";"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_017019986.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041630582.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017023991.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017016411.1 6 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;MetaCyc: PWY-5514;Reactome: R-HSA-446210 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine" XP_041632841.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017020081.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017016710.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041632244.1 42 Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-9609690 "B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Meiotic synapsis";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"DNA methylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Early Events" XP_017017719.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017033313.1 13 Reactome: R-HSA-8866654;Reactome: R-HSA-5358346;Reactome: R-HSA-532668;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-110320;Reactome: R-HSA-5362768;Reactome: R-HSA-3371511;Reactome: R-HSA-5689896;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-9646399 "E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog ligand biogenesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"Translesion Synthesis by POLH";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"HSF1 activation";"Ovarian tumor domain proteases";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Protein methylation";"Aggrephagy" XP_017038442.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017025033.1 14 MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-6728 "Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle" XP_017034330.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017029520.1 7 Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-9020265;Reactome: R-HSA-9018896;Reactome: R-HSA-6798695;Reactome: R-HSA-9023661;Reactome: R-HSA-9018676 "Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Neutrophil degranulation";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of D-series resolvins" XP_017031735.1 11 MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-3861;MetaCyc: PWY-7456 "Mannitol biosynthesis";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II";"Beta-(1,4)-mannan degradation" XP_017019455.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_041632199.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017030515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041632243.1 42 Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-2299718;Reactome: R-HSA-427389 "Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"DNA methylation";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis";"RMTs methylate histone arginines";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_017034754.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017027288.1 14 MetaCyc: PWY-8052;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109 "2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Synthesis of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_017020209.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017036439.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736 "Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors" XP_017036029.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017028132.1 1 Reactome: R-HSA-419771 "Opsins" XP_017020871.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017024997.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Synthesis of PC";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation" XP_017021026.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017035124.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041631695.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017036434.1 12 Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-451308 "Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor" XP_017035471.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017016927.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_017035049.1 22 Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-432142 "T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL" XP_017018291.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_017022018.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-418594 "G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G alpha (i) signalling events" XP_017038146.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017025823.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017033257.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017036389.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017028583.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_041631767.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017018798.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_017029398.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_041632922.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017020093.1 8 KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1 "Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis" XP_017033412.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_041631863.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017023960.1 6 Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-110362 "Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair" XP_041630893.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017037364.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017028987.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_017035365.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_017020528.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017028870.1 31 KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;Reactome: R-HSA-2426168;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;MetaCyc: PWY-5971;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-7723;MetaCyc: PWY-5973;MetaCyc: PWY-4381;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-5366;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-8012;MetaCyc: PWY-5142;MetaCyc: PWY-5994;MetaCyc: PWY-6799;MetaCyc: PWY-5367;Reactome: R-HSA-75105;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-7663 "Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Activation of gene expression by SREBF (SREBP)";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Bacterial bioluminescence";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Petroselinate biosynthesis";"Fatty acyl-CoA biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Gondoate biosynthesis (anaerobic)" XP_041633125.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017036760.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade" XP_017018746.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017031639.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017034456.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017032110.1 5 MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6 "Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_017038178.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017033039.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017016670.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017017571.1 7 Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798 "Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Ligand-receptor interactions";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell" XP_017037070.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_017028293.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024424.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017027613.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017031833.1 8 MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_017028855.1 7 MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282 "5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_017029201.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_041633071.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017037785.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017028331.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_017024945.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017035278.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017026125.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_017036949.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017018355.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017038517.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017020527.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017033251.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017028387.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017019312.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017028976.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_017024240.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017025556.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017020474.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017033437.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017017610.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017019592.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017017527.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017034674.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_017021786.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017020389.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_017025062.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_017031596.1 14 Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-977225 "Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation" XP_017023985.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_017024238.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_017028820.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017028065.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017019448.1 20 Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Polymerase switching";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_041630675.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017022223.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_017017810.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017038520.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_041632463.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041633464.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_041632319.1 7 MetaCyc: PWY-3781;MetaCyc: PWY-5083;MetaCyc: PWY-6692;Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2;MetaCyc: PWY-4302;Reactome: R-HSA-6799198 "Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Fe(II) oxidation";"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis" XP_017032206.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017029744.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017036569.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017020002.1 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7222 "Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_017018214.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017029197.1 13 KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-561 "Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_017034853.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017017572.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway" XP_017017811.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017022899.2 7 Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry" XP_017026882.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017026321.2 9 Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-975634 "Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Retinoid metabolism and transport" XP_017018044.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017035272.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017027496.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017035127.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017029629.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017037072.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017029885.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_041630636.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_041632322.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017018220.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_017037542.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_017029916.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017034881.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017029634.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017031673.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017025263.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017017033.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017025620.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017029915.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_041632464.1 42 Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379 "PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"RMTs methylate histone arginines";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Oxidative Stress Induced Senescence";"DNA methylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events" XP_017032747.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017030697.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" XP_017030843.1 6 MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_017021025.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017038449.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017036685.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041632198.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041633443.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_041632807.1 13 Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-1489509 "VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"DAG and IP3 signaling" XP_041631634.1 7 MetaCyc: PWY-5083;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-4302;Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198 "NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Oxidative phosphorylation";"Complex I biogenesis" XP_017034071.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017029219.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_017034164.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017017427.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017027401.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_017022100.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017016382.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_017026674.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017018252.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017021492.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017027312.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017020488.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017030919.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_041633072.1 22 MetaCyc: PWY-5384;KEGG: 00500+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-6981;MetaCyc: PWY-7347;Reactome: R-HSA-5628897;MetaCyc: PWY-5054;Reactome: R-HSA-70263;MetaCyc: PWY-6992;MetaCyc: PWY-6142;KEGG: 00030+5.3.1.9;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-622;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5659;MetaCyc: PWY-7238;MetaCyc: PWY-5514;Reactome: R-HSA-6798695;KEGG: 00520+5.3.1.9;MetaCyc: PWY-621;MetaCyc: PWY-3801 "Sucrose degradation IV (sucrose phosphorylase)";"Starch and sucrose metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Chitin biosynthesis";"Sucrose biosynthesis III";"TP53 Regulates Metabolic Genes";"D-sorbitol biosynthesis I";"Gluconeogenesis";"1,5-anhydrofructose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Starch biosynthesis";"Glycolysis / Gluconeogenesis";"GDP-mannose biosynthesis";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Neutrophil degranulation";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation III (sucrose invertase)";"Sucrose degradation II (sucrose synthase)" XP_017018114.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359 "Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation" XP_017022732.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-5625886;Reactome: R-HSA-983231;Reactome: R-HSA-9029569 "Estrogen-dependent gene expression";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_017021845.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_041632442.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017020688.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_017025341.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017033429.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_041631532.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017030244.2 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_041632769.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017034909.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_017036649.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_041632637.1 42 Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-427413 "SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"DNA methylation";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression" XP_041631644.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017028294.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017025378.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_017026174.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017018454.1 8 Reactome: R-HSA-8950505;Reactome: R-HSA-6791055;KEGG: 00030+2.2.1.2;Reactome: R-HSA-163754;Reactome: R-HSA-71336;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;MetaCyc: PWY-1861 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_017034455.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017037985.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017020047.1 10 KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042 "Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)" XP_017032525.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_041630918.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017038130.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017019593.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017029573.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017019517.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017034270.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_017030355.1 7 MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7185 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I" XP_017026097.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017021774.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017028968.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017031695.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_017027157.1 8 Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354 "Activation of AMPK downstream of NMDARs";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy" XP_017036876.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017017403.1 27 Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-111367;Reactome: R-HSA-72086;Reactome: R-HSA-77588;Reactome: R-HSA-9010553;Reactome: R-HSA-6803529;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-167242;Reactome: R-HSA-159230;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-167152;Reactome: R-HSA-975957;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-77595;Reactome: R-HSA-975956;Reactome: R-HSA-72165 "RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Capping";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"FGFR2 alternative splicing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP Dependant Mature mRNA";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"Processing of Intronless Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Splicing - Minor Pathway" XP_041632182.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017020908.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_041632634.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357 "TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1" XP_017027387.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_017028729.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017022671.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017018558.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017020560.1 3 MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_041631232.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017020149.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214 "SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins" XP_017029731.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_017024776.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017028301.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017028921.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017033418.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017020668.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017021788.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017027143.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_017030173.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017022489.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_017032534.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017035403.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017024595.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017032561.1 18 Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4 "Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Ether lipid metabolism" XP_017031251.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017018892.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017031434.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017023654.1 11 MetaCyc: PWY-7524;MetaCyc: PWY-6383;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6174;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7560 "Mevalonate pathway III (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Methylerythritol phosphate pathway II" XP_017024015.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_017031572.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_017029883.1 17 Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397 "Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Polymerase switching";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_017035998.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017024322.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017023120.1 12 Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" XP_017036350.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017034870.1 42 MetaCyc: PWY-6945;MetaCyc: PWY-5136;MetaCyc: PWY-7654;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-7726;MetaCyc: PWY-5138;KEGG: 00592+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7606;MetaCyc: PWY-6944;MetaCyc: PWY-7656;MetaCyc: PWY-6946;MetaCyc: PWY-5109;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-5789;MetaCyc: PWY-6863;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6435;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35 "Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation II (plant peroxisome)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Phenylalanine metabolism";"Glutaryl-coa degradation";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"alpha-Linolenic acid metabolism";"Valine, leucine and isoleucine degradation";"Fatty acid salvage";"Lysine degradation";"Toluene degradation";"Benzoate degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"Propanoate metabolism";"Fatty acid degradation";"Geraniol degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to hexanol (engineered)";"Butanoate metabolism";"Caprolactam degradation";"Limonene and pinene degradation";"2-methylpropene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Tryptophan metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Aminobenzoate degradation";"Fatty acid elongation" XP_017027702.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017035586.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_017023541.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_017031166.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017021167.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017034240.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017016619.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017017716.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_017025711.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017027525.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017034594.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism" XP_017034828.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017022374.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017037365.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_017027342.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" XP_017027872.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017029966.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017023076.1 11 Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_017028158.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017035818.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_041633075.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017027739.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_017025668.1 19 Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041 "Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Chylomicron clearance";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Chylomicron assembly";"VLDL clearance";"Scavenging by Class B Receptors";"VLDL assembly";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"LDL clearance";"LDL remodeling" XP_017036211.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751 "SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Degradation of DVL";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity" XP_017020485.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017033826.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017022293.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II" XP_017020408.1 1 Reactome: R-HSA-419771 "Opsins" XP_017022338.1 11 Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604 "Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling" XP_017025106.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_017018582.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_017035896.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017016591.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017018381.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017025115.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017026757.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_017024881.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017031672.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017035169.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes" XP_017016617.1 5 MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017033028.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_017038162.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017017068.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017028888.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017038396.1 3 Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517 "Ca2+ pathway";"cGMP effects";"Rap1 signalling" XP_017023582.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_041630932.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017023173.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_017034959.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017032526.1 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017024627.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017031504.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_017033173.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017020754.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017027199.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-180910 "NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs" XP_017030478.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017038649.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017020168.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_017038571.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017020625.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_017032999.1 1 Reactome: R-HSA-419771 "Opsins" XP_041630611.1 44 Reactome: R-HSA-982772;Reactome: R-HSA-170968;Reactome: R-HSA-375165;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-8943724;Reactome: R-HSA-2559585;Reactome: R-HSA-881907;Reactome: R-HSA-456926;Reactome: R-HSA-8940973;Reactome: R-HSA-5668599;Reactome: R-HSA-6802952;Reactome: R-HSA-2559582;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-1295596;Reactome: R-HSA-879415;Reactome: R-HSA-6811558;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-6802946;Reactome: R-HSA-5674499;Reactome: R-HSA-445144;Reactome: R-HSA-112409;Reactome: R-HSA-5674135;Reactome: R-HSA-2029482;Reactome: R-HSA-5654727;Reactome: R-HSA-6802948;Reactome: R-HSA-8939211;Reactome: R-HSA-9649948;Reactome: R-HSA-5654726;Reactome: R-HSA-5673001;Reactome: R-HSA-9627069;Reactome: R-HSA-5654733;Reactome: R-HSA-5663213;Reactome: R-HSA-444257;Reactome: R-HSA-202670;Reactome: R-HSA-74749;Reactome: R-HSA-162658;Reactome: R-HSA-2871796;Reactome: R-HSA-3371453;Reactome: R-HSA-198753;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654732 "Growth hormone receptor signaling";"Frs2-mediated activation";"NCAM signaling for neurite out-growth";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of PTEN gene transcription";"Oncogene Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Thrombin signalling through proteinase activated receptors (PARs)";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate NADPH Oxidases";"Signaling by BRAF and RAF fusions";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Spry regulation of FGF signaling";"Advanced glycosylation endproduct receptor signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"Signaling by moderate kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"Signal transduction by L1";"RAF-independent MAPK1/3 activation";"MAP2K and MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of FGFR2 signaling";"Signaling by high-kinase activity BRAF mutants";"ESR-mediated signaling";"Signaling downstream of RAS mutants";"Negative regulation of FGFR1 signaling";"RAF/MAP kinase cascade";"Regulation of the apoptosome activity";"Negative regulation of FGFR4 signaling";"RHO GTPases Activate WASPs and WAVEs";"RSK activation";"ERKs are inactivated";"Signal attenuation";"Golgi Cisternae Pericentriolar Stack Reorganization";"FCERI mediated MAPK activation";"Regulation of HSF1-mediated heat shock response";"ERK/MAPK targets";"mTOR signaling pathway";"Negative regulation of FGFR3 signaling" XP_017031669.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_041632017.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017027546.1 9 KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-6703;MetaCyc: PWY-6147;Reactome: R-HSA-1474151 "Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_017018654.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017016537.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017018374.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_041631584.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017022353.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_017020007.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_017025822.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_041633271.1 5 MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;Reactome: R-HSA-196757 "Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Metabolism of folate and pterines" XP_017030528.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017019065.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_017029018.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017019006.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017017947.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_041630715.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017031330.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017025481.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604 "Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling" XP_041631690.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017036743.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017029662.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_041631942.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017022842.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_017026889.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017029016.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017025576.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017027338.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017035598.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017023065.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_017018609.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" XP_017031782.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017035669.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017030828.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017027933.1 18 MetaCyc: PWY-6642;MetaCyc: PWY-6638;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1;MetaCyc: PWY-5913 "(R)-cysteate degradation";"Sulfolactate degradation III";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Arginine biosynthesis";"Partial TCA cycle (obligate autotrophs)" XP_017028486.1 12 MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Glycogen synthesis";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I" XP_017019462.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017024073.1 4 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_017029496.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II" XP_017019009.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_041631915.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017023394.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017017813.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017022835.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105 "Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport" XP_017023092.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017035332.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017016609.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_017018086.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017021128.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017032239.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017034368.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_017037130.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017034158.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017037498.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017028433.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183 "DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand" XP_017026233.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017019576.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Degradation of DVL";"Hedgehog ligand biogenesis" XP_017018493.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017027822.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_041633515.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017026845.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_041632236.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017038406.1 9 MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_017037520.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_041631143.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017024666.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" XP_017019905.1 20 KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-7384;Reactome: R-HSA-1268020;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5537;Reactome: R-HSA-71403 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Mitochondrial protein import";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)" XP_017038331.1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_017021359.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017018009.1 11 KEGG: 00240+2.1.3.2;MetaCyc: PWY-7791;MetaCyc: PWY-5154;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5686;Reactome: R-HSA-500753 "Pyrimidine metabolism";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis II";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis" XP_017037069.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_017023193.1 5 Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88 "Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism" XP_041633244.1 5 KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22 "Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_017021647.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_041632027.1 42 Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582 "Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Processing of DNA double-strand break ends";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"RMTs methylate histone arginines";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)" XP_017017804.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017027017.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017031315.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017019716.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_017035890.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017023129.1 17 MetaCyc: PWY-4202;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1 "Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Purine salvage";"Inosine 5'-phosphate degradation";"Purine metabolism";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism" XP_041633091.1 8 MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;MetaCyc: PWY-7524 "Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway III (archaea)" XP_017034501.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041630591.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041631981.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017038145.1 7 KEGG: 00240+2.7.4.14;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7176 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis" XP_017021715.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017030720.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017034180.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_017022672.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017032102.1 10 Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017029603.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041633171.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_041630734.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_041632019.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017035910.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_017020912.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017037599.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017031855.1 1 Reactome: R-HSA-916853 "Degradation of GABA" XP_017026720.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_041631792.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017033546.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017028935.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017026736.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017018345.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017024363.1 3 KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K" XP_017026756.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_017018183.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017022874.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017030760.2 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_017023858.1 15 MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6901 "Glycerol degradation to butanol";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Superpathway of glucose and xylose degradation" XP_017030382.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017027449.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017030598.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017024956.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017018820.1 9 MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7411;Reactome: R-HSA-1483166 "Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA" XP_017019086.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-936837 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases" XP_017018772.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017022153.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_017025841.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017025329.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041632137.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017025852.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_041632318.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017031006.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017017773.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017025666.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017016329.1 52 Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-5250924;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-167287;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-749476;Reactome: R-HSA-73772 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"B-WICH complex positively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape" XP_017025709.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321 "mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_017016815.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_041630590.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017027148.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_017031849.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_017026426.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017027901.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017035899.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017027798.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630 "Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3" XP_017028709.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_041633507.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017026719.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_041632891.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017023165.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017027520.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017020347.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017035895.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017033547.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_041632655.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017019901.1 7 MetaCyc: PWY-6724;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221 "Starch degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)" XP_017023579.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017027434.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017018471.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017027366.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_041632866.1 10 KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7571 "Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I";"PPARA activates gene expression";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis" XP_017028267.1 11 Reactome: R-HSA-71403;MetaCyc: PWY-7268;MetaCyc: PWY-6549;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-7124 "Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)" XP_017022557.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50 "HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation" XP_017024152.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017019671.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_017031163.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_041631793.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017027437.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017018356.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017028831.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_041632998.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017031535.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017020711.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017027069.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017036578.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_017025720.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_041632196.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017028849.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017024421.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_041633418.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017036993.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_017034366.1 3 MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2 "UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism" XP_017025624.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017034596.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_017033847.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017023223.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017020610.2 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017023016.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017025455.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017021546.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017024506.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017027902.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017036968.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5873;Reactome: R-HSA-1268020;MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6978 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Plastoquinol-9 biosynthesis II" XP_017019520.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017037753.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_041630281.1 5 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017028395.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017017430.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017026229.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017038069.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041631768.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017034119.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017029981.1 4 Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922 "Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis" XP_017025672.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017034232.1 3 Reactome: R-HSA-6790901;Reactome: R-HSA-8951664;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017017407.1 18 Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051 "Acyl chain remodelling of PS";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I" XP_017030319.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017033160.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017034370.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017032009.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017017809.1 4 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)" XP_017018390.1 8 MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4 "Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Purine metabolism" XP_017024585.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_017022796.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017033861.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_041632657.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017034061.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_017021944.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_017029043.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017020980.1 56 Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785 "APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"Degradation of DVL";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome" XP_041633077.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017021100.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017035274.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017035167.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes" XP_017034956.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017026880.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017032801.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017021140.1 5 Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201 "Metabolism of folate and pterines";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I" XP_017021449.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"UCH proteinases";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_017031761.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_041632015.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017038006.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017030758.2 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017037971.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_041632065.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017016708.1 7 MetaCyc: PWY-6614;Reactome: R-HSA-1474151;MetaCyc: PWY-3841;Reactome: R-HSA-69205;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3 "Tetrahydrofolate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Folate biosynthesis";"One carbon pool by folate" XP_017018583.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017031488.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017030779.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_017030948.1 10 MetaCyc: PWY-7344;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527 "UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation" XP_017022834.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105 "Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport" XP_017034584.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation" XP_017036436.1 12 Reactome: R-HSA-447038;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244 "NrCAM interactions";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation" XP_017017018.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017024108.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_017016656.1 9 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation" XP_017035878.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_017021493.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-210991 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Basigin interactions" XP_017024558.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017033031.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017024080.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_017022498.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017021662.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_017021321.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017017388.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_041632333.1 7 Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER" XP_017025028.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017018167.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017036916.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_017022884.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017034171.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017022737.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017017789.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041630375.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_041630466.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-6811440 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network" XP_017034029.1 19 Reactome: R-HSA-418885;Reactome: R-HSA-8950505;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-389359;Reactome: R-HSA-525793;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-983231;Reactome: R-HSA-114604 "DCC mediated attractive signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"EGFR downregulation";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"CD28 dependent Vav1 pathway";"Myogenesis";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade" XP_017017478.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_017033436.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017025893.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017033526.1 5 KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-6798695;Reactome: R-HSA-71336;MetaCyc: PWY-8060 "Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I" XP_017036641.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017037526.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017028069.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017034097.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017017772.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017028930.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017030038.1 4 Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017038448.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017018352.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017025016.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_041632615.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017025994.1 7 KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;Reactome: R-HSA-446193;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;MetaCyc: PWY-5265 "N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)" XP_017035486.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017021246.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017035391.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017038444.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017029769.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017016990.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_041631230.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017020472.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017036761.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K Cascade" XP_017019457.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_017018250.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017018354.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017035267.1 7 MetaCyc: PWY-6922;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-46 "L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Arginine and proline metabolism";"Urea cycle";"Arginine biosynthesis";"Urea cycle";"Putrescine biosynthesis III" XP_017018110.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594 "PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events" XP_041632617.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017024701.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_017021800.2 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_017037827.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017038239.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017031719.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017020458.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017016554.1 15 Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-174048 "Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_017023979.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_017030289.1 1 MetaCyc: PWY-6938 "NADH repair" XP_017036228.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017026260.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041632619.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017017599.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017037455.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017020640.1 24 Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Cilium Assembly";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_041632804.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017031685.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_041630793.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017026890.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_041630324.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017018103.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation" XP_017030716.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041632095.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017029626.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017037333.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017033926.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017028883.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_017027235.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017035777.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017017788.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins" XP_041633021.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-5972 "(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)" XP_017022186.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017027030.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-427413 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression" XP_017019227.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017029105.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017025467.1 6 MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788 "Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling" XP_017022375.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017023565.1 6 MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_017034504.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_017020882.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_041633084.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024332.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041632206.1 42 Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-5250924 "Oxidative Stress Induced Senescence";"DNA methylation";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression" XP_017030967.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1" XP_017025886.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017026991.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes" XP_017024877.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-212300 "Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"DNA methylation";"Oxidative Stress Induced Senescence";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PRC2 methylates histones and DNA" XP_017018201.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041632154.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_017016942.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017033026.1 23 Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-418217;Reactome: R-HSA-392451;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-4086398 "G beta:gamma signalling through BTK";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through PI3Kgamma";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G alpha (s) signalling events";"Ca2+ pathway" XP_017021324.1 12 KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550 "Purine metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Selenocompound metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se" XP_017034390.1 5 KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560 "Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II" XP_041630763.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017020045.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017016370.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017035490.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041631971.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017025737.1 20 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"Thermogenesis";"Amino acids regulate mTORC1";"mTOR signalling";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"Macroautophagy";"Human cytomegalovirus infection";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"mTOR signaling pathway" XP_017031716.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_041632212.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017020056.1 10 KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042 "Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)" XP_017029008.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017024529.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_017027147.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_017026232.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017034951.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_017034262.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418594 "PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (i) signalling events" XP_017031661.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1 "Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism" XP_041631791.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041630754.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017031014.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017027824.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_041632169.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041633391.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017034314.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017025494.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_041632188.1 42 Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582 "Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"Meiotic synapsis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)" XP_017034307.1 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism" XP_017024744.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_017035811.1 16 Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-164939;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"LDL clearance";"Recycling pathway of L1";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017029730.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_017024774.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_041632197.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017018797.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017027766.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_017037501.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017017668.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_041632486.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017024587.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041632876.1 7 MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-7039 "Choline biosynthesis III";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule" XP_017025173.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_041632120.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_041630993.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017038441.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017032476.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017026259.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017017681.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017018634.1 3 Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969 "Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina" XP_041631173.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017033577.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_041631905.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017026617.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_017028029.1 7 Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201;MetaCyc: PWY-7980 "Cristae formation";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis" XP_017031391.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017031739.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017020886.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017020586.1 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919 "Degradation of the extracellular matrix";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils" XP_017033904.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II" XP_017021716.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_041632709.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_041632570.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_041630553.1 13 MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403 "TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citric acid cycle (TCA cycle)" XP_041630726.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017030656.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_041632187.1 42 Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632 "Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PRC2 methylates histones and DNA";"HCMV Early Events";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"DNA methylation";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"Meiotic synapsis" XP_017036378.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024599.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017027273.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_041632171.1 42 Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-110331 "SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PRC2 methylates histones and DNA";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"DNA methylation";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"RMTs methylate histone arginines";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine" XP_017026130.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017022395.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_041632773.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017022414.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7574 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II" XP_017017693.1 7 KEGG: 00230+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-7219 "Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis" XP_017031676.1 6 Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_017028054.1 3 MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695 "Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation" XP_017023126.1 17 KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6609;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-74259;MetaCyc: PWY-6620;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-4202;MetaCyc: PWY-7179 "Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Purine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine catabolism";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation I" XP_017016480.1 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_017018826.1 6 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism" XP_017018160.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_017025623.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_017028823.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017037283.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I" XP_017029570.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_017034433.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017016698.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_017026420.1 15 MetaCyc: PWY-6142;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-1042 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)" XP_017024379.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_017028060.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017034125.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041631968.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_017017016.1 4 Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807 "Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III" XP_017027380.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_017026318.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017037499.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017035196.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017038311.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017023788.1 57 Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425 "APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1" XP_017031853.1 32 Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-75953 "Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"mRNA Capping";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation" XP_017018093.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017026888.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_017036503.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017035455.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017016360.1 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_017032104.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017033062.1 4 Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" XP_017030505.2 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017019497.1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_017020540.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017025010.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017031688.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017028933.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017018075.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017031484.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_017027649.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017016567.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017019207.1 16 Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+4.2.1.11 "Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis" XP_017025058.1 17 MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis" XP_017035734.1 14 Reactome: R-HSA-75109;Reactome: R-HSA-8931987;MetaCyc: PWY-8053;Reactome: R-HSA-2426168;MetaCyc: PWY-8055;MetaCyc: PWY-5667;Reactome: R-HSA-9018519;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587 "Triglyceride biosynthesis";"RUNX1 regulates estrogen receptor mediated transcription";"Anandamide biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Estrogen-dependent gene expression";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)" XP_017038071.1 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-380994 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017020269.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_041631699.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_041630923.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017016939.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017033254.1 3 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_041631904.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017037284.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017018151.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017023859.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017034448.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_017025048.1 12 Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017026231.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017023030.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017033089.1 4 Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768 "Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_017029720.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_041632422.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017024817.1 9 MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-7003 "Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycerol degradation to butanol" XP_041630938.1 12 Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-451308 "Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor" XP_041632904.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017024375.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_041632927.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_017030704.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_017026299.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021309.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017020206.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017038593.1 13 KEGG: 00740+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821 "Riboflavin metabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Tunicamycin biosynthesis" XP_017020545.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_017028828.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017024667.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760 "snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation" XP_017024029.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017033256.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017034120.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017025820.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017018905.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_017025100.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017023253.2 19 Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888 "Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Chylomicron clearance";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"LDL clearance";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"VLDL assembly";"Scavenging by Class B Receptors";"VLDL clearance";"Chylomicron assembly" XP_017018113.1 11 Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594 "Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events" XP_017027367.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_041630731.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017029113.1 7 Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-381070 "Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"IRE1alpha activates chaperones" XP_041631774.1 10 Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-5689880 "Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases" XP_017027502.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017027230.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017028304.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017038557.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_017026192.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017023090.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_017030320.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017035384.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017029449.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017027750.1 6 Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483 "TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1" XP_041630505.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041631035.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_041631913.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017020762.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017020724.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017017925.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_041633486.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017036358.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_017029644.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_017023448.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017027963.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex" XP_017033828.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017028896.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_017030345.1 2 KEGG: 00514+2.4.1.222;Reactome: R-HSA-1912420 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in Golgi" XP_017027481.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_017035144.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333 "SUMOylation of SUMOylation proteins";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_041632228.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017023734.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041633126.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017021143.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017034879.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017025625.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017023167.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_017021123.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_017022832.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017018975.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017019560.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017023667.1 15 KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6901 "Purine metabolism";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Superpathway of glucose and xylose degradation" XP_017021638.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_017026439.1 13 KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590 "Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Glutathione conjugation" XP_017038587.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" XP_017022188.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017027381.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_017026777.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017024917.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017034894.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017029224.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_041631734.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_017034966.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017019815.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017033645.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_017032502.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017023034.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017024623.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017034192.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017027807.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017033041.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017029755.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017031553.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017019456.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_017035510.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017019130.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017018953.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_041631941.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017027917.1 9 KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142 "Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017036872.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_017033880.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017025821.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017033253.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-2467813;Reactome: R-HSA-5620912;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" XP_017016955.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017027245.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017016909.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017025775.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_041632419.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017031811.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017019270.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017031644.1 5 KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383 "Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_017035641.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017036679.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230 "Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane" XP_041632507.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017016713.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017035541.1 14 MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis" XP_017018649.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041631903.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017023860.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_017036435.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_017024780.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_041630983.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017031313.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017028860.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017031462.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017034225.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_041632210.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017031754.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_017025583.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"VLDL assembly";"Chylomicron assembly" XP_017024747.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017038010.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017025739.1 3 MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway" XP_017027026.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-427413 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression" XP_017017950.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017038551.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_017028819.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017017036.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_017035863.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_017030826.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_017036139.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_041631967.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_017027566.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017016906.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017022565.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9630222 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding" XP_017033803.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_041631341.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system" XP_017017557.1 10 Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352 "Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"3-phosphoinositide biosynthesis" XP_017021776.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017034792.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017033400.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859 "SUMOylation of SUMOylation proteins";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly" XP_017019381.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_041632091.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017022021.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_017025572.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017035725.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017034484.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017037496.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017021705.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017038463.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;Reactome: R-HSA-1368108 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_017028051.1 3 KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695 "Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation" XP_017025670.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017019583.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_041630661.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751 "Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Regulation of PTEN stability and activity" XP_017035392.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017030702.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779 "RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_041632038.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_017034794.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017026997.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017022636.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017030171.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017023773.1 40 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-168325 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis" XP_017027506.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017037926.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_041631662.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017019320.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017019636.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_041633329.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017038194.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017021269.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017018092.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_017027890.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_017025964.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017021354.1 1 Reactome: R-HSA-419771 "Opsins" XP_017021035.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021573.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_017036664.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017031247.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017016797.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017025148.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017027545.1 9 MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5663 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I" XP_017031505.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017022187.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017021448.1 11 Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017021093.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017018877.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017030316.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017033639.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017032014.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017020556.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041632992.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993 "WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors" XP_017022571.1 14 MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166 "CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA" XP_017021576.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport" XP_017033353.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_017020005.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_017030827.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_017020090.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017031096.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017036639.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017027518.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_017023158.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017024927.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_017035711.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017030874.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017035241.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017032550.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017016754.1 3 Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_041632618.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017036227.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_041631882.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017025626.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_017034188.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017035996.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_017034305.1 4 KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_017034516.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017020264.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017034970.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017038347.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017033095.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017036448.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324 "Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017031741.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041632928.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017017590.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041630757.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017016928.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_041631765.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017038192.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017037477.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017031138.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017030883.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017038457.1 15 Reactome: R-HSA-6811558;Reactome: R-HSA-912631;Reactome: R-HSA-416476;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-1660499;Reactome: R-HSA-1433557;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-1266695;Reactome: R-HSA-389357 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of signaling by CBL";"G alpha (q) signalling events";"Interleukin receptor SHC signaling";"RET signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Synthesis of PIPs at the plasma membrane";"Signaling by SCF-KIT";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Interleukin-7 signaling";"CD28 dependent PI3K/Akt signaling" XP_017017980.1 9 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017027891.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017034143.1 4 Reactome: R-HSA-189483;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-917937 "Heme degradation";"Porphyrin and chlorophyll metabolism";"Heme degradation I";"Iron uptake and transport" XP_017029107.1 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" XP_017032135.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017038605.2 13 Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-216083 "Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Collagen chain trimerization";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Anchoring fibril formation";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Laminin interactions";"Integrin cell surface interactions" XP_017037560.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017019891.1 20 MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7858;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)" XP_041632227.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041631231.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_041632488.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017026005.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017032218.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017028483.1 12 KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;MetaCyc: PWY-7238;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527 "Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Glycogen synthesis";"Glycerolipid metabolism";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation" XP_017018603.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_041631802.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017019458.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_041630656.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017033616.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6807505 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes" XP_017024677.1 57 Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178 "Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017016380.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_017026657.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017036749.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017020898.1 56 Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-180534 "CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"UCH proteinases";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4" XP_017037273.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017027438.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017020032.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_041632882.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017030757.2 3 Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017035866.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_017026297.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024025.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017037829.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017020904.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017031347.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017018480.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_017032226.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017025272.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017030295.1 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_017035125.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017018492.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041632134.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017016926.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_017035883.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017027320.1 7 KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2 "D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis" XP_017029199.1 7 Reactome: R-HSA-416476;Reactome: R-HSA-8957275;Reactome: R-HSA-140837;Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Post-translational protein phosphorylation";"Intrinsic Pathway of Fibrin Clot Formation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017029770.1 25 Reactome: R-HSA-8939256;Reactome: R-HSA-8931987;Reactome: R-HSA-8941326;Reactome: R-HSA-8939245;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8941332;Reactome: R-HSA-8941284;Reactome: R-HSA-8951936;Reactome: R-HSA-8941858;Reactome: R-HSA-9616222;Reactome: R-HSA-8935964;Reactome: R-HSA-8951911;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8941333;Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8939243;Reactome: R-HSA-8877330;Reactome: R-HSA-8939246;Reactome: R-HSA-8940973;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-8939242 "RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates p14-ARF";"Regulation of RUNX3 expression and activity";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates expression of components of tight junctions";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes" XP_017034830.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017037527.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017026768.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_017020057.1 10 KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042 "Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)" XP_017033897.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017035199.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041633415.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_041630263.1 4 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin" XP_017020897.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017037567.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017025239.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017025309.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017033618.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017016560.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021328.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Neutrophil degranulation";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_017021518.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017026904.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601 "Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_017025630.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_041633536.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017026154.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_017025238.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017025681.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017034113.1 3 MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001 "CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis";"Sialic acid metabolism" XP_017036877.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13 "Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism" XP_017036772.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_017020484.1 10 Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23 "Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"HS-GAG degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_017024594.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_041630272.1 22 Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-196299 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade" XP_017029745.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_041632741.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_041631524.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017025174.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017031168.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_017024149.1 8 Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_017035502.1 26 Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-4615885;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-69205;Reactome: R-HSA-8866654;Reactome: R-HSA-6804114;Reactome: R-HSA-174437;Reactome: R-HSA-1362277;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174414 "Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA replication proteins";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"G1/S-Specific Transcription";"E3 ubiquitin ligases ubiquitinate target proteins";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Removal of the Flap Intermediate from the C-strand";"Transcription of E2F targets under negative control by DREAM complex";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere" XP_017018819.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination" XP_017035336.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017033626.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017036441.1 12 MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5673001 "Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade" XP_017018117.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-5610787 "PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state" XP_017025517.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017021083.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017026476.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017028414.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_017027682.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-674695 "HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events" XP_017034517.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017021581.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation" XP_017029295.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685 "Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy" XP_017031710.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_041631715.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017031157.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017022708.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017027674.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017027660.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017022570.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51 "Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism" XP_017034887.2 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_017030703.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation" XP_017032962.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_017035025.1 7 Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363 "Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_017027915.1 9 KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142 "Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017020996.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017031159.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017036062.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_017037018.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017035901.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017029939.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017030942.1 10 Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821 "Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_017019565.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017018555.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017026812.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_017037598.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" XP_017019759.1 13 KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101 "Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation" XP_017025974.1 8 KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Oxidative phosphorylation";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Photosynthesis";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017029048.1 28 Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-110312 "Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"HSF1 activation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Translesion synthesis by REV1" XP_017026264.1 5 Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148 "Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017021169.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017022471.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_041632658.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017026725.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_017037901.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024187.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601 "Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_041631495.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017027364.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017020199.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017034668.1 3 KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_017029130.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-8939243 "Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017028400.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017031785.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017037073.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017027158.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017036116.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017035024.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phytate degradation I" XP_017033582.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017038298.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_017034800.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648 "Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes" XP_017018546.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-112382 "Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"Formation of RNA Pol II elongation complex" XP_017028771.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017029633.1 30 Reactome: R-HSA-1170546;Reactome: R-HSA-5684264;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-2644607;Reactome: R-HSA-5610783;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-2122947;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-68949 "Prolactin receptor signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Interleukin-1 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH1 Intracellular Domain Regulates Transcription";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"Iron uptake and transport";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Orc1 removal from chromatin" XP_017028931.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017018636.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766 "Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown" XP_017024778.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_041632850.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017035047.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017025680.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017035865.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_017020350.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_041633060.1 4 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017034275.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_041632772.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017028313.1 4 KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14 "Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism" XP_017027220.1 56 Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577 "The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"UCH proteinases";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21" XP_017033742.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017033998.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes" XP_017033413.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017029117.1 7 Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-381183 "PERK regulates gene expression";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes" XP_017028766.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041631545.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017026670.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_017033305.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_041632791.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017020301.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017031463.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_041630261.1 4 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin" XP_017030288.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017028958.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_017019631.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017027808.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017027409.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017023563.1 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181 "Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" XP_017034825.1 7 KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-8043 "Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis" XP_017024313.1 7 Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis" XP_017038407.1 9 KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6351 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_017035134.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017017675.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017017948.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017020745.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_041631201.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615 "G alpha (i) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation" XP_017035887.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017017981.1 9 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection" XP_017036347.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_041633538.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017031180.1 11 MetaCyc: PWY-5695;MetaCyc: PWY-6999;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6596;MetaCyc: PWY-6606;Reactome: R-HSA-8851680;Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;MetaCyc: PWY-6607 "Inosine 5'-phosphate degradation";"Theophylline degradation";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Butyrophilin (BTN) family interactions";"Purine catabolism";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation I" XP_017032906.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_017036445.1 12 Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-447038 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions" XP_017032600.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017021578.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation" XP_041631455.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017018606.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017037049.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017038576.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017020608.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017024862.1 6 Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980 "Cristae formation";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Mitochondrial protein import";"Photosynthesis";"ATP biosynthesis" XP_017018650.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017029399.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017028449.2 15 Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017021182.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017037472.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017034778.1 25 Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-380270;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295 "Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"Recruitment of mitotic centrosome proteins and complexes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation" XP_017030986.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_017017600.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_017019633.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017026001.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes" XP_017025900.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_017017485.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" XP_017027498.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017032221.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation" XP_017020208.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017036452.1 12 Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-447038 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions" XP_017036450.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017019186.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017027630.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041633263.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017026078.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017017729.1 4 KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931 "Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis" XP_017034604.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017035558.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041633437.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_041631587.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017017326.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017029538.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017023159.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_017017448.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017029880.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_041633163.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017021805.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017031708.1 6 Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017037265.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_017020017.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017028859.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017026253.1 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" XP_017025733.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I" XP_017027036.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017037404.1 31 MetaCyc: PWY-5366;MetaCyc: PWY-5147;Reactome: R-HSA-199220;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-8049;MetaCyc: PWY-7663;MetaCyc: PWY-6519;MetaCyc: PWY-5367;Reactome: R-HSA-75105;MetaCyc: PWY-7664;MetaCyc: PWY-5989;Reactome: R-HSA-2426168;MetaCyc: PWY-6113;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-5971;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-4381;MetaCyc: PWY-5973;MetaCyc: PWY-7723 "Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Pederin biosynthesis";"Gondoate biosynthesis (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence" XP_017019037.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017033301.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_017035846.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017018744.1 5 Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism" XP_017032551.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017038118.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017036714.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_017018927.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_041631585.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017033722.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017019226.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017035009.1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801 "Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PS" XP_017028978.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017025987.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-159230 "Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA" XP_017027027.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206 "NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha" XP_017027463.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017021125.1 4 Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism" XP_017028199.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_017023766.1 6 MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52 "L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis";"Cysteine and methionine metabolism" XP_017019991.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017034644.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017034688.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_041630347.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_017019899.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-7238;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25 "Neutrophil degranulation";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch degradation II";"Starch and sucrose metabolism" XP_017018799.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_041631534.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017021787.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017028200.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome" XP_017036620.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017022495.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041630884.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017033334.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017028982.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_017032583.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017017697.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017030845.1 14 MetaCyc: PWY-7782;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8051 "Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I" XP_017026091.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017036279.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Gap junction degradation";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017029781.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_017034486.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017031552.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017038079.1 9 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-446353;Reactome: R-HSA-446343;KEGG: 05165+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Cell-extracellular matrix interactions";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Human papillomavirus infection" XP_017034687.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017019710.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_017032131.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017020010.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041630589.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017033414.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_041632166.1 42 Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749 "Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"DNA methylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs" XP_017022742.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_017029743.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017020131.1 4 Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211 "ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes" XP_017027383.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017023504.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_041631454.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017021890.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017029728.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017037886.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017026265.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719 "Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation" XP_017019697.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_017016998.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_017027098.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017021367.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_017025175.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017026040.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017035640.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017029726.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017019632.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017026320.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017019817.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017019984.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA" XP_017036570.1 11 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017034759.1 5 KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403 "Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling" XP_017022389.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020 "Regulation of HSF1-mediated heat shock response";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import" XP_041633514.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017033759.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017019664.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017021545.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_017037632.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017022332.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_041632138.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041631771.1 4 Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50 "Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism" XP_041630517.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_017034376.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017029887.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_017021447.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017024382.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017035894.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017020385.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_017018608.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017027697.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017029349.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_017022152.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_041630621.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_017018158.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017025950.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_017020013.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_017029757.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017033885.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017035713.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017036294.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_017026745.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602 "Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017022521.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024765.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_017031487.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_017024083.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_017037678.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017022165.1 13 KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-561 "Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_017034776.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017038020.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041632906.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-9609690;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300 "Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"RMTs methylate histone arginines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"DNA methylation";"HCMV Early Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA" XP_017038009.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017016763.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017027142.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041631744.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_017024022.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017016359.1 33 Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-69202;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-69231;Reactome: R-HSA-69656;Reactome: R-HSA-167246 "RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Cyclin E associated events during G1/S transition";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Cyclin D associated events in G1";"Cyclin A:Cdk2-associated events at S phase entry";"Tat-mediated elongation of the HIV-1 transcript" XP_017017714.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_017027628.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017019544.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176409 "Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins" XP_041633497.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017018369.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones" XP_041633446.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017021934.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017036836.1 12 Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-75893;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-5362798;Reactome: R-HSA-177929;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"TNF signaling";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017026672.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_041631097.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017022755.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017027324.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2 "Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism" XP_041633127.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017027515.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017017584.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017017946.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017023534.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017025349.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_041630733.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017024910.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_017034172.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017026891.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017028927.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017027447.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017027411.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events" XP_017033161.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017030185.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017029019.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531 "SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus" XP_017033875.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_041632508.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017016993.1 6 Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616 "Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_041630931.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_041631623.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017036688.1 22 Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids" XP_017032742.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017028421.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017033625.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041633417.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_041632220.1 42 Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279 "NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Processing of DNA double-strand break ends";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"DNA methylation";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"RMTs methylate histone arginines";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_017022134.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017037253.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017035370.1 11 Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1 "p38MAPK events";"mTOR signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection" XP_041632190.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017028007.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017029498.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017027493.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017017985.1 9 Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection" XP_017017952.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017019298.1 17 Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-69183;Reactome: R-HSA-5696400 "Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Polymerase switching";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER" XP_017033477.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017032173.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017034509.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_017025574.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_041631083.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_017023091.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017022536.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017022030.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_041632028.1 42 Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-427413;Reactome: R-HSA-977225 "SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis";"RMTs methylate histone arginines";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Early Events";"Oxidative Stress Induced Senescence";"DNA methylation";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation" XP_017031755.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_017036166.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017027594.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_017034732.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017021185.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017024145.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017026894.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017027190.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017036432.1 12 Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066 "Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"NrCAM interactions";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017035973.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017028725.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017028932.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017034167.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569 "MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_017037059.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017033409.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017032530.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_041632726.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017028733.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_041633509.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-68949 "Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Hedgehog ligand biogenesis";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin" XP_017018303.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_017022816.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017031158.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017034797.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017024588.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_017017238.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017027024.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206 "NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha" XP_017034205.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017035097.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017019641.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017021335.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_041632627.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017018674.1 17 Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-8951664;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-2467813 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Neddylation";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids" XP_017031731.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_041632660.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017030552.1 9 Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367 "Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_041630657.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017028021.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017036255.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017020144.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017026175.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017036295.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_017028195.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" XP_017024832.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_041631304.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202 "G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition" XP_017035992.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_041631588.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017032037.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017035583.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017023128.1 17 MetaCyc: PWY-7179;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;MetaCyc: PWY-6644;Reactome: R-HSA-74259;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-6627;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1 "Purine deoxyribonucleosides degradation I";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Purine metabolism";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism" XP_017022009.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_017016859.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017036427.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_017024775.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017024001.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017030007.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_041632767.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_041630305.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_017034832.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_041632636.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1" XP_017020372.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II" XP_017034396.1 4 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_041632809.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-5607763 "FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"DAG and IP3 signaling";"Ion homeostasis";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation" XP_017031164.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017036457.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_017035368.1 33 Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-209543;Reactome: R-HSA-450302;Reactome: R-HSA-5689896;Reactome: R-HSA-937042;Reactome: R-HSA-168927;Reactome: R-HSA-166058;Reactome: R-HSA-975110;Reactome: R-HSA-5689880;Reactome: R-HSA-975871;Reactome: R-HSA-933541;Reactome: R-HSA-933542;Reactome: R-HSA-6811558;Reactome: R-HSA-9645460;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-445989;Reactome: R-HSA-1257604;Reactome: R-HSA-209560;Reactome: R-HSA-168638;Reactome: R-HSA-193692;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-975155;Reactome: R-HSA-205043;Reactome: R-HSA-937041;Reactome: R-HSA-937039;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-975138 "TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"p75NTR recruits signalling complexes";"activated TAK1 mediates p38 MAPK activation";"Ovarian tumor domain proteases";"IRAK2 mediated activation of TAK1 complex";"TICAM1, RIP1-mediated IKK complex recruitment";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Ub-specific processing proteases";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated IRF7 activation";"TRAF6 mediated NF-kB activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Alpha-protein kinase 1 signaling pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"PIP3 activates AKT signaling";"NF-kB is activated and signals survival";"NOD1/2 Signaling Pathway";"Regulated proteolysis of p75NTR";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"MyD88 dependent cascade initiated on endosome";"NRIF signals cell death from the nucleus";"IKK complex recruitment mediated by RIP1";"IRAK1 recruits IKK complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_017029756.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_041631172.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017022573.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782 "Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis" XP_017022743.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_017033352.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_041631486.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_041630954.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017027120.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex" XP_017024561.1 11 KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-1660516;Reactome: R-HSA-168138;Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;MetaCyc: PWY-6352;Reactome: R-HSA-109704 "Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"3-phosphoinositide biosynthesis";"PI3K Cascade" XP_041633421.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017035311.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017031809.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_017018952.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017021118.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_041633215.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017020259.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017028861.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_041631158.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017024233.1 14 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"Macroautophagy";"Intraflagellar transport";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_041631788.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017016808.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_017035708.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017029904.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_017027319.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921 "TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation" XP_017028975.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017016910.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017036145.1 6 Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism" XP_017025712.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_041631990.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017021717.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_041630462.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017023543.1 15 MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-5484 "1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_017031645.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"MHC class II antigen presentation";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Gap junction assembly";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_017028699.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017026510.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017033868.1 20 MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism" XP_017035921.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017033902.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017018080.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017033159.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017017752.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782 "Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis" XP_041632203.1 42 Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-110330 "HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"DNA methylation";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"Meiotic synapsis";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_017036207.1 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017030094.1 9 MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533 "Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis" XP_017026262.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017031856.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_017027240.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_017035819.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017034410.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_017023605.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_017020063.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria" XP_017028710.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_041630859.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017024339.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017024642.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017021001.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_017021113.1 3 Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3 "Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism" XP_041632413.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017034690.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017031618.1 15 Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated" XP_017027940.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_017032683.2 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017018391.1 8 MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4 "Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Purine metabolism" XP_017030042.2 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_017025788.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis" XP_017031249.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017029739.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017023691.1 5 Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532 "Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)" XP_017023746.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" XP_017021339.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_017030663.1 6 KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484 "Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_017025029.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017028394.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_041630849.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017023779.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017035142.2 14 Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Estrogen-dependent gene expression" XP_017016346.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-9018519 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression" XP_017035421.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017030622.1 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017021860.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017031824.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017017945.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_017029923.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017021370.1 21 KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7221;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7198;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7219;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7187 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_017027202.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017018159.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_017026377.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017035714.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_041631169.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017033027.1 23 Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-418217 "Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"Ca2+ pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through PLC beta" XP_017027673.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024030.1 6 MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_017028527.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_017030950.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041630896.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_017032822.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017018212.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017018500.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_041632706.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017036356.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_041631991.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017025274.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017025276.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017020262.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_041632122.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017026827.1 6 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017019543.1 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_017032566.1 16 Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Estrogen-dependent gene expression" XP_041632704.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017029971.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017037792.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017035670.1 3 KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262;MetaCyc: PWY-6100 "Lysine degradation";"Carnitine synthesis";"L-carnitine biosynthesis" XP_041632466.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017038028.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol" XP_017027924.1 11 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes" XP_017018177.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017027483.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_017030351.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017020355.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041632902.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017033545.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017034910.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_017036449.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066 "Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017027459.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017020961.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017022019.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040 "G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation" XP_017028719.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017033835.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017034012.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017022073.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017028794.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_041631982.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017035341.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017019990.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017035867.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_017029878.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_041631865.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017021231.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017018511.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017031155.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017026169.1 6 MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-70370;Reactome: R-HSA-5609978 "Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Defective GALT can cause Galactosemia" XP_017036904.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32 "alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_017037639.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_041630339.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_017034375.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017029549.1 179 Reactome: R-HSA-977225;Reactome: R-HSA-5654732;Reactome: R-HSA-205043;Reactome: R-HSA-69541;Reactome: R-HSA-8876493;Reactome: R-HSA-8948751;Reactome: R-HSA-5654733;Reactome: R-HSA-9615710;Reactome: R-HSA-8866654;Reactome: R-HSA-174048;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-6804756;Reactome: R-HSA-5654726;Reactome: R-HSA-1253288;Reactome: R-HSA-5696395;Reactome: R-HSA-5693607;Reactome: R-HSA-2408557;Reactome: R-HSA-179409;Reactome: R-HSA-75815;Reactome: R-HSA-450321;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8866652;Reactome: R-HSA-8852276;Reactome: R-HSA-110312;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-6791226;Reactome: R-HSA-168928;Reactome: R-HSA-174178;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-9633012;Reactome: R-HSA-5656121;Reactome: R-HSA-156827;Reactome: R-HSA-168927;Reactome: R-HSA-975110;Reactome: R-HSA-4641263;Reactome: R-HSA-2173788;Reactome: R-HSA-1358803;Reactome: R-HSA-4641258;Reactome: R-HSA-192823;Reactome: R-HSA-8856828;Reactome: R-HSA-2122947;Reactome: R-HSA-5696394;Reactome: R-HSA-450408;Reactome: R-HSA-937041;Reactome: R-HSA-5205685;Reactome: R-HSA-937039;Reactome: R-HSA-6804760;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-9637628;Reactome: R-HSA-445989;Reactome: R-HSA-8939902;Reactome: R-HSA-209560;Reactome: R-HSA-5654727;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-168638;Reactome: R-HSA-9636383;Reactome: R-HSA-3769402;Reactome: R-HSA-5696397;Reactome: R-HSA-6804757;Reactome: R-HSA-72764;Reactome: R-HSA-5675482;Reactome: R-HSA-5607764;Reactome: R-HSA-532668;Reactome: R-HSA-917729;Reactome: R-HSA-9646399;Reactome: R-HSA-5607761;Reactome: R-HSA-110314;Reactome: R-HSA-2894862;Reactome: R-HSA-1295596;Reactome: R-HSA-5689603;Reactome: R-HSA-5684264;Reactome: R-HSA-450302;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-8948747;Reactome: R-HSA-9013507;Reactome: R-HSA-5656169;Reactome: R-HSA-2559585;Reactome: R-HSA-175474;Reactome: R-HSA-6807004;Reactome: R-HSA-3322077;Reactome: R-HSA-5689880;Reactome: R-HSA-400253;Reactome: R-HSA-5358346;Reactome: R-HSA-5689901;Reactome: R-HSA-2173795;Reactome: R-HSA-6782210;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-72706;Reactome: R-HSA-5362768;Reactome: R-HSA-6781827;Reactome: R-HSA-5678895;Reactome: R-HSA-110320;Reactome: R-HSA-174490;Reactome: R-HSA-9010553;Reactome: R-HSA-6781823;Reactome: R-HSA-1169408;Reactome: R-HSA-1236382;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-2122948;Reactome: R-HSA-4608870;Reactome: R-HSA-936440;Reactome: R-HSA-3134975;Reactome: R-HSA-162588;Reactome: R-HSA-72689;Reactome: R-HSA-2672351;Reactome: R-HSA-8856825;Reactome: R-HSA-912631;Reactome: R-HSA-9613829;Reactome: R-HSA-975144;Reactome: R-HSA-182971;Reactome: R-HSA-5675221;Reactome: R-HSA-209543;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-937042;Reactome: R-HSA-975957;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-9013973;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-2979096;Reactome: R-HSA-2173796;Reactome: R-HSA-2173791;Reactome: R-HSA-5696400;Reactome: R-HSA-5676590;Reactome: R-HSA-1799339;Reactome: R-HSA-8849469;Reactome: R-HSA-156902;Reactome: R-HSA-5610785;Reactome: R-HSA-8875360;Reactome: R-HSA-8863795;Reactome: R-HSA-195253;Reactome: R-HSA-3785653;Reactome: R-HSA-975956;Reactome: R-HSA-201681;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-5668541;Reactome: R-HSA-2691232;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5685942;Reactome: R-HSA-9645460;Reactome: R-HSA-5687128;Reactome: R-HSA-936964;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-6783310;Reactome: R-HSA-5689896;Reactome: R-HSA-5357905;Reactome: R-HSA-69601;Reactome: R-HSA-917937;Reactome: R-HSA-9033241;Reactome: R-HSA-174113;Reactome: R-HSA-5689877;Reactome: R-HSA-901032 "Amyloid fiber formation";"Negative regulation of FGFR3 signaling";"NRIF signals cell death from the nucleus";"Stabilization of p53";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of PTEN stability and activity";"Negative regulation of FGFR4 signaling";"Late endosomal microautophagy";"E3 ubiquitin ligases ubiquitinate target proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Regulation of TP53 Activity through Phosphorylation";"Negative regulation of FGFR1 signaling";"Downregulation of ERBB4 signaling";"Formation of Incision Complex in GG-NER";"Processing of DNA double-strand break ends";"Selenocysteine synthesis";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin-dependent degradation of Cyclin D";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translesion synthesis by REV1";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translesion synthesis by POLI";"L13a-mediated translational silencing of Ceruloplasmin expression";"TICAM1, RIP1-mediated IKK complex recruitment";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of FZD by ubiquitination";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2:ERBB3 signaling";"Degradation of DVL";"Viral mRNA Translation";"Clathrin-mediated endocytosis";"NOTCH1 Intracellular Domain Regulates Transcription";"DNA Damage Recognition in GG-NER";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"IKK complex recruitment mediated by RIP1";"Pink/Parkin Mediated Mitophagy";"IRAK1 recruits IKK complex";"Regulation of TP53 Activity through Methylation";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"Modulation by Mtb of host immune system";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of RUNX2 expression and activity";"NF-kB is activated and signals survival";"Negative regulation of FGFR2 signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NOD1/2 Signaling Pathway";"Prevention of phagosomal-lysosomal fusion";"Deactivation of the beta-catenin transactivating complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Degradation";"Eukaryotic Translation Termination";"Regulation of necroptotic cell death";"CLEC7A (Dectin-1) signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Aggrephagy";"Dectin-1 mediated noncanonical NF-kB signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Spry regulation of FGF signaling";"UCH proteinases";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"activated TAK1 mediates p38 MAPK activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of PTEN localization";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Termination of translesion DNA synthesis";"Oncogene Induced Senescence";"Assembly Of The HIV Virion";"Negative regulation of MET activity";"Glycogen synthesis";"Ub-specific processing proteases";"Circadian Clock";"Hedgehog ligand biogenesis";"Metalloprotease DUBs";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Defective CFTR causes cystic fibrosis";"Translesion Synthesis by POLH";"Membrane binding and targetting of GAG proteins";"Regulation of expression of SLITs and ROBOs";"Formation of TC-NER Pre-Incision Complex";"ISG15 antiviral mechanism";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Activated NOTCH1 Transmits Signal to the Nucleus";"Asymmetric localization of PCP proteins";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of innate immune responses to cytosolic DNA";"Budding and maturation of HIV virion";"Formation of a pool of free 40S subunits";"Stimuli-sensing channels";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of signaling by CBL";"Chaperone Mediated Autophagy";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"EGFR downregulation";"Negative regulation of MAPK pathway";"p75NTR recruits signalling complexes";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"IRAK2 mediated activation of TAK1 complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translesion synthesis by POLK";"Dual incision in TC-NER";"TICAM1-dependent activation of IRF3/IRF7";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Dual Incision in GG-NER";"NIK-->noncanonical NF-kB signaling";"SRP-dependent cotranslational protein targeting to membrane";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Peptide chain elongation";"GLI3 is processed to GLI3R by the proteasome";"InlB-mediated entry of Listeria monocytogenes into host cell";"Downregulation of ERBB2 signaling";"Degradation of beta-catenin by the destruction complex";"Myoclonic epilepsy of Lafora";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TCF dependent signaling in response to WNT";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TNFR2 non-canonical NF-kB pathway";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"HDR through Homologous Recombination (HRR)";"Alpha-protein kinase 1 signaling pathway";"MAPK6/MAPK4 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Fanconi Anemia Pathway";"Ovarian tumor domain proteases";"Regulation of TNFR1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Iron uptake and transport";"Peroxisomal protein import";"SCF-beta-TrCP mediated degradation of Emi1";"Josephin domain DUBs";"ER Quality Control Compartment (ERQC)" XP_017031011.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_041632235.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017018174.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017024049.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_041632320.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017030506.2 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017030933.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017026669.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949 "IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA" XP_017023053.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13 "Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism" XP_017034782.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017019660.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017029601.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017023981.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_041630850.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_041631314.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017033441.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017038271.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017038205.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017031468.1 3 Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153 "eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis" XP_017019491.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_017035470.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017032818.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_017018353.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017022734.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017025912.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_041631853.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041630906.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017029893.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017036926.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_017033780.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_017032505.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017025271.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017024065.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041633520.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017037152.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017030258.1 8 KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1 "Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Galactose metabolism" XP_017025728.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017032568.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity" XP_017027860.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_041630610.1 44 Reactome: R-HSA-5663213;Reactome: R-HSA-5654733;Reactome: R-HSA-9627069;Reactome: R-HSA-202670;Reactome: R-HSA-74749;Reactome: R-HSA-444257;Reactome: R-HSA-2871796;Reactome: R-HSA-162658;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654732;Reactome: R-HSA-3371453;Reactome: R-HSA-198753;Reactome: R-HSA-112409;Reactome: R-HSA-5674499;Reactome: R-HSA-445144;Reactome: R-HSA-6802946;Reactome: R-HSA-2029482;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-5654726;Reactome: R-HSA-8939211;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-879415;Reactome: R-HSA-1295596;Reactome: R-HSA-6811558;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-170968;Reactome: R-HSA-982772;Reactome: R-HSA-9634638;Reactome: R-HSA-9635465;Reactome: R-HSA-375165;Reactome: R-HSA-6802952;Reactome: R-HSA-8940973;Reactome: R-HSA-5668599;Reactome: R-HSA-456926;Reactome: R-HSA-2559585;Reactome: R-HSA-881907;Reactome: R-HSA-8943724;Reactome: R-HSA-2559582 "RHO GTPases Activate WASPs and WAVEs";"Negative regulation of FGFR4 signaling";"Regulation of the apoptosome activity";"ERKs are inactivated";"Signal attenuation";"RSK activation";"FCERI mediated MAPK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"mTOR signaling pathway";"Negative regulation of FGFR3 signaling";"Regulation of HSF1-mediated heat shock response";"ERK/MAPK targets";"RAF-independent MAPK1/3 activation";"Negative feedback regulation of MAPK pathway";"Signal transduction by L1";"Signaling by moderate kinase activity BRAF mutants";"Regulation of actin dynamics for phagocytic cup formation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"Negative regulation of FGFR1 signaling";"ESR-mediated signaling";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"Advanced glycosylation endproduct receptor signaling";"Spry regulation of FGF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"Frs2-mediated activation";"Growth hormone receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Suppression of apoptosis";"NCAM signaling for neurite out-growth";"Signaling by BRAF and RAF fusions";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate NADPH Oxidases";"Thrombin signalling through proteinase activated receptors (PARs)";"Oncogene Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Regulation of PTEN gene transcription";"Senescence-Associated Secretory Phenotype (SASP)" XP_017020244.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017023516.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017028730.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017038633.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017019459.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_017034261.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615 "G alpha (i) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation" XP_041630904.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017035595.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_017030128.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_041631537.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017024638.1 3 KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" XP_017036075.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017032814.1 3 KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685 "Pyrimidine metabolism";"Purine metabolism";"Detoxification of Reactive Oxygen Species" XP_041632735.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_017037146.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017032071.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017035982.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017034179.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-212300 "SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA" XP_017016842.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_017034824.1 7 Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2 "Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism" XP_017027942.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017037794.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_017031442.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017035944.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72695 "Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017029588.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017026055.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017027602.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017033488.1 6 MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261 "Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I" XP_017030383.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017026911.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017038312.1 11 Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-9627069 "TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity" XP_017027638.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" XP_017035522.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_017026456.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_017018184.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017037419.1 5 Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668 "Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017028673.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017036054.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-159231 "Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_017038144.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_017020624.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_017026907.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017025872.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_017031713.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_041632766.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_041630902.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041630270.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017034317.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_041632770.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017038445.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017017984.2 9 KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017028024.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017033247.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017016957.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_017036209.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_017036647.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017022497.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6 "Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism" XP_017027040.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" XP_017023468.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921 "DAG and IP3 signaling";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"VEGFR2 mediated cell proliferation" XP_017022133.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017029715.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017036644.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361 "Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins" XP_017022769.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017026440.1 13 MetaCyc: PWY-7112;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-6370;MetaCyc: PWY-2261 "4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle" XP_017036905.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32 "alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_017021356.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017038586.1 12 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_017025616.1 11 Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-350054;Reactome: R-HSA-72163 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Notch-HLH transcription pathway";"mRNA Splicing - Major Pathway" XP_017027258.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017028316.1 4 Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism" XP_017021574.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877 "COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase" XP_017019595.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_017022135.1 6 Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238 "Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation V";"Starch degradation III";"Starch and sucrose metabolism";"Sucrose biosynthesis II" XP_017026982.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_017016356.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_017018156.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017028511.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017020479.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017036422.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017037112.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_041631013.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_017018195.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090 "MHC class II antigen presentation";"Neutrophil degranulation";"Collagen degradation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures" XP_017028985.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_041631643.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_041632653.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017020670.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_017029499.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017019265.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_017027243.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017029927.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017022757.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017021372.1 8 KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5083633 "Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_017031860.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_017024624.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017036359.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_017031493.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017021695.2 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017031737.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017017669.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017018778.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154 "Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin" XP_041633491.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017031709.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017029200.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_017018921.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017022872.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_017035542.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_041631841.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017016915.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017036941.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN" XP_017037900.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021289.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017029742.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017019468.1 9 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_017024756.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Stachyose degradation";"Galactose metabolism" XP_017019103.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017017429.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017030667.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_017027895.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017024723.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017028445.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017021311.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_017038315.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017034784.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017027361.1 2 Reactome: R-HSA-8875656;Reactome: R-HSA-8873719 "MET receptor recycling";"RAB geranylgeranylation" XP_017018298.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017024757.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism" XP_017024863.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017031278.2 14 Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408 "Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation" XP_017026976.1 9 MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112 "Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification" XP_017016934.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_017027962.2 5 Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941 "Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses" XP_017029494.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_017023125.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_017023945.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017034711.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017034065.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017027543.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017023017.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017036577.2 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017034271.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_017026495.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017038485.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_017018637.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" XP_017028197.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_017035430.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017030712.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017037340.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507 "Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation" XP_017029569.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_041630937.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-442982 "Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017022751.1 42 Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-427413 "SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"DNA methylation";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression" XP_017036900.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017036410.1 42 Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-73728;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-2559582 "Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Processing of DNA double-strand break ends";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"RMTs methylate histone arginines";"HCMV Early Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Oxidative Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)" XP_017036928.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017034874.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017030597.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017033001.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017033666.1 7 KEGG: 00030+3.1.3.11;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11 "Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms" XP_041631483.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017019090.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Long-term potentiation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation" XP_017021233.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017017891.1 4 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans" XP_017022756.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017016940.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017025036.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_017028506.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017024903.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_017033565.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017022776.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-196025 "Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions" XP_017024628.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041631590.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_041631630.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_041630592.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017024871.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017025268.1 6 KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol degradation I";"Glycerol-3-phosphate shuttle" XP_017025834.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017019662.1 7 KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12 "Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_017029571.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017034436.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017027323.1 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation" XP_017024381.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017021247.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017021924.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape" XP_041631067.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_017035678.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017036710.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_017016416.1 13 MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-7384;Reactome: R-HSA-71403 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)" XP_041631140.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017018178.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017027032.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017024581.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017030593.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017023695.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017030714.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017036437.1 12 Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-451308 "Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor" XP_017034108.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_017028563.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_017029902.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017021558.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-8853884 "Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX" XP_017021572.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_017031787.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Macroautophagy";"Neutrophil degranulation" XP_017023562.1 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_017036610.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017027432.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017022230.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_017022280.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017031542.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017025582.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_017020487.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_017027574.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017026513.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_041630958.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_017017796.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569 "ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_017034873.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017030245.1 5 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism";"Formation of apoptosome";"Regulation of the apoptosome activity" XP_017035814.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017017027.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_017037538.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017031120.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017035717.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017029894.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_017022766.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041632867.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017025629.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_017023061.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017028471.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017025035.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017027755.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_017027813.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017021288.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017017802.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017021797.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017032849.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_017028302.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017026490.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017028311.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017038340.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017016671.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017021287.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017018377.1 3 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism" XP_017016730.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017022493.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017026228.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017027241.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_041631482.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_041631780.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_017029740.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017031594.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_041632335.1 7 Reactome: R-HSA-2173795;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395;Reactome: R-HSA-110362 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair" XP_017026471.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation" XP_017016686.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017036867.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_017035372.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_041632645.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_041632650.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017021098.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021986.1 14 MetaCyc: PWY-8053;Reactome: R-HSA-975634;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis II";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism" XP_017016945.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017025921.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017028306.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017023689.1 5 MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine catabolism" XP_017026052.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017027802.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" XP_017030664.1 8 MetaCyc: PWY-5154;MetaCyc: PWY-4984;KEGG: 00220+6.3.4.5;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-5 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Canavanine biosynthesis" XP_041633032.1 10 Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856 "NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling" XP_017025818.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017023185.1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_017036109.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017031494.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017028905.1 9 Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-9656255;Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-110328;Reactome: R-HSA-9657050;Reactome: R-HSA-110329;Reactome: R-HSA-9656256 "Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Binding";"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Localization";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing" XP_017030241.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017024027.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017025190.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_017029597.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_017020966.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017033157.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017018153.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017036442.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017037128.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_017030413.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2 "Glutathione metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism" XP_017024528.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017017445.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017017283.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017021696.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017020300.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017029718.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017017411.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017029129.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751 "Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Regulation of PTEN stability and activity" XP_041633138.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418592 "G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1" XP_017023967.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017034053.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_017024234.1 14 Reactome: R-HSA-1632852;Reactome: R-HSA-5620924;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436 "Macroautophagy";"Intraflagellar transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic" XP_017021711.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017037630.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017024636.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017018413.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017037108.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-8934593 "MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity" XP_017025396.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017017619.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017036141.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_017027497.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017031607.1 13 MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537 "Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V" XP_017027516.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017036268.1 5 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation" XP_017029194.1 13 Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-5690 "Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)" XP_017028436.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017028812.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017017028.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017037416.1 31 MetaCyc: PWY-7664;MetaCyc: PWY-5989;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-5971;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-4381;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-5366;MetaCyc: PWY-5147;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-6799;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-7663;MetaCyc: PWY-8049;MetaCyc: PWY-6519;MetaCyc: PWY-5367;Reactome: R-HSA-75105 "Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Pederin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Fatty acyl-CoA biosynthesis" XP_017026519.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_017018247.1 6 Reactome: R-HSA-9033241;Reactome: R-HSA-193368;Reactome: R-HSA-390247;Reactome: R-HSA-9033500;Reactome: R-HSA-2046106;Reactome: R-HSA-389887 "Peroxisomal protein import";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Beta-oxidation of very long chain fatty acids";"TYSND1 cleaves peroxisomal proteins";"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of pristanoyl-CoA" XP_017033596.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017029104.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017029845.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_017031781.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017028537.1 3 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3108214 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins" XP_017029205.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017037004.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017035578.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis" XP_041630300.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-241 "Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_017034515.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_017026365.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017027690.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017024526.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_041631078.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017035554.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis" XP_017033336.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017038490.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017024144.1 30 Reactome: R-HSA-5610783;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-1170546;Reactome: R-HSA-5684264;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-400253;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902 "Degradation of GLI2 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Prolactin receptor signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"Circadian Clock";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity" XP_017026290.1 13 KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590 "Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Glutathione conjugation" XP_017018549.1 10 MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722 "Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate" XP_017030472.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017018094.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017018213.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916 "Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation" XP_017035882.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_041630799.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017034280.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_041632317.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017035328.1 17 Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1 "Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Human papillomavirus infection";"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis" XP_017024036.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017030658.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_017025253.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017018089.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017023538.1 9 MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7411 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)" XP_017030614.1 5 Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" XP_017037866.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017020142.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017018633.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017023891.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017031617.1 15 Reactome: R-HSA-5467333;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340 "APC truncation mutants are not K63 polyubiquitinated";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex" XP_017038156.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017032965.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184 "Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"UCH proteinases";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_041633492.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017016762.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017029063.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017033332.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017037868.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017038196.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_041630502.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017033098.1 14 MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_041631632.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017024278.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017028143.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657 "ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes" XP_017036602.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_041631117.1 9 MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-1855204 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol" XP_017035721.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_017029785.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017035888.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-5620922 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium" XP_017028328.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_017027408.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events" XP_041632899.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_017035621.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs" XP_017031633.1 33 Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214 "RHO GTPases Activate Formins";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins" XP_017038627.1 12 Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_017016916.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017021226.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_017028361.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017023982.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017027800.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_017026184.1 29 KEGG: 00260+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-7118;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-5078;MetaCyc: PWY-5076;KEGG: 00980+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-6587;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5480;MetaCyc: PWY-5082;MetaCyc: PWY-6313;MetaCyc: PWY-5486;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00350+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-5751;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6342;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-5057;MetaCyc: PWY-7013 "Glycine, serine and threonine metabolism";"L-tryptophan degradation V (side chain pathway)";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"Acetaldehyde biosynthesis I";"L-isoleucine degradation II";"L-leucine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Naphthalene degradation";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol III";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to isobutanol (engineered)";"Pyruvate fermentation to ethanol I";"L-methionine degradation III";"Serotonin degradation";"Pyruvate fermentation to ethanol II";"Retinol metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Tyrosine metabolism";"alpha-Linolenic acid metabolism";"L-phenylalanine degradation III";"Phenylethanol biosynthesis";"Fatty acid degradation";"Noradrenaline and adrenaline degradation";"Drug metabolism - cytochrome P450";"Salidroside biosynthesis";"L-valine degradation II";"(S)-propane-1,2-diol degradation" XP_041630419.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_017023127.1 17 MetaCyc: PWY-5532;MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-7179-1 "Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Purine salvage";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Purine metabolism";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Neutrophil degranulation";"Purine catabolism";"Purine deoxyribonucleosides degradation II" XP_017036645.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870 "Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins" XP_017035050.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752 "Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated" XP_017020490.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_017030751.1 7 MetaCyc: PWY-6351;MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PI";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)" XP_017023102.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic" XP_017033475.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-432040 "PKA activation in glucagon signalling";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_017035577.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041632705.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017025497.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_017024864.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017022143.1 9 MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94 "Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_041630903.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017038560.1 10 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-6807004 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity" XP_017036225.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_041632898.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_017033328.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017035761.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_017037571.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017020635.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017027744.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis" XP_017019284.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017033335.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017036742.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017017462.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017017679.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017018978.1 1 Reactome: R-HSA-9640463 "Wax biosynthesis" XP_041631149.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-203927 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis" XP_017037363.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017020926.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017027297.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_041633235.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024024.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017038154.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017022425.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_017031076.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_017018893.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017035067.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_017021627.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017029600.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017019996.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_041630465.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695 "Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neutrophil degranulation" XP_017023755.1 6 KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004 "Methane metabolism";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I" XP_017029196.1 13 MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-561;Reactome: R-HSA-71403 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)" XP_017030412.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13 "Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism" XP_041633495.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017023987.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_017034446.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_017034915.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041630960.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017019691.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017034297.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017018145.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017032052.1 4 KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes" XP_017034691.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017033396.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017024844.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017028856.1 8 KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;Reactome: R-HSA-209905;MetaCyc: PWY-5049;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2 "Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis" XP_017035837.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" XP_017034482.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017027934.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041630760.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017037947.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017026832.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_041632832.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_017034643.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017021933.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017025902.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017030636.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017035023.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I" XP_017038277.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_041633552.1 14 KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.42;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-75896;MetaCyc: PWY-8055;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I" XP_017024244.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017018630.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017025871.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_017025955.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017023645.1 5 MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2 "L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_017037332.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017029833.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_041632613.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017023077.1 11 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_017018152.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017038369.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017029537.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041632277.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660 "G alpha (i) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway" XP_017027321.1 7 Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539 "Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism" XP_017024754.1 10 Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7571;MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922 "PPARA activates gene expression";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I" XP_041630463.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695 "Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neutrophil degranulation" XP_017038063.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670 "G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway" XP_017023811.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017026258.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_041632341.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017019704.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_041630279.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_017019156.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017030203.1 4 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Unwinding of DNA" XP_017018357.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017034793.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_041632611.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017035710.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_017022197.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017025120.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_017033290.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017028804.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_041632267.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017037335.1 5 Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24 "p38MAPK events";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"mTOR signaling pathway" XP_017018163.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017030402.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017034883.1 1 Reactome: R-HSA-9640463 "Wax biosynthesis" XP_017022155.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017037870.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017024071.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017031547.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017016321.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017027489.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_041630916.1 9 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection" XP_017027233.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017036908.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_041630795.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_017028496.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017021645.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_017025054.1 17 Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-200425;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00620+6.4.1.2 "Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Pyruvate metabolism" XP_017018358.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017020539.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017021084.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017027254.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017020362.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017027951.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017036994.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-241 "Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_041630359.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017029376.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_017035515.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017032602.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017034958.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017026988.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" XP_017022768.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017022182.1 18 KEGG: 00220+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1 "Arginine biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism" XP_017018155.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017037842.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017019128.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER" XP_017025903.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_017032482.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017029393.1 14 Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Macroautophagy";"Intraflagellar transport";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_017034184.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017037410.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_017029394.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017026176.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_017032955.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017035815.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017017653.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017026727.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids";"Cilium Assembly";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_017020967.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017027633.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017037646.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017021698.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_041633103.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" XP_017034089.1 3 Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins" XP_017038447.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017038161.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_017029211.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017035015.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017029547.1 5 Reactome: R-HSA-917937;Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-2173789 "Iron uptake and transport";"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"Neddylation";"TGF-beta receptor signaling activates SMADs" XP_041633537.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_041631621.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017035642.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017027512.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_017026633.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_017022179.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_017018473.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017037849.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_017019208.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017027314.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_017028995.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017029536.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017017404.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_041632131.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017030655.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017020482.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017025034.1 2 KEGG: 00520+1.6.2.2;Reactome: R-HSA-1237044 "Amino sugar and nucleotide sugar metabolism";"Erythrocytes take up carbon dioxide and release oxygen" XP_017036552.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017031486.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_041630968.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex" XP_017028919.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017038004.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017022072.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017018951.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017019091.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Signaling downstream of RAS mutants" XP_017027492.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_041631453.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017021625.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017025316.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017031532.1 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017038116.1 10 MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism" XP_017033563.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry" XP_017024625.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017028989.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_017018091.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_017032006.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017034665.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" XP_041632955.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017032711.1 3 KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_017025245.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017034100.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_017021058.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017022504.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017038286.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_017037132.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017021122.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017021857.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017021957.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017017754.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51 "Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism" XP_017038186.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_017024597.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017031744.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017025888.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_017018077.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_041633553.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_017028822.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_041632063.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017028376.1 5 MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Neutrophil degranulation" XP_017037570.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017020303.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017038285.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017026741.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017026715.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017032065.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017025676.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017028453.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017020382.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017021456.1 5 Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-532668 "Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017037603.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_041633257.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041631452.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017034058.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017020353.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_017021958.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017030987.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017030719.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017036694.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358747 "Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated" XP_017021498.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_017033074.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017023045.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017023144.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017025948.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017017069.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017021190.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_017025451.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017032745.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017028811.1 6 KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599;MetaCyc: PWY-7346 "Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_017024156.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription" XP_017029450.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017022287.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017028947.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017024000.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_017037524.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017016393.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40 "Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis" XP_017016431.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_017035014.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_041630264.1 4 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism" XP_017017057.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-2206305 "Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D" XP_017023533.1 3 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_017023200.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017038164.1 17 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6790901 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol" XP_017018762.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017022661.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_041631620.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017016764.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017035269.1 7 MetaCyc: PWY-6922;MetaCyc: PWY-31;KEGG: 00330+3.5.3.1;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-4984;MetaCyc: PWY-46 "L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Arginine and proline metabolism";"Arginine biosynthesis";"Urea cycle";"Urea cycle";"Putrescine biosynthesis III" XP_017020238.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017032203.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017025348.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017035827.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_017024777.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017027941.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_041632827.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_017018591.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_017034301.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_017019131.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_017030819.1 12 KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972 "Human cytomegalovirus infection";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017029560.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017025395.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017023599.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_017026457.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_017022847.1 4 MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;Reactome: R-HSA-389661 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation" XP_017029965.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017033762.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017035351.1 13 KEGG: 00562+3.1.4.11;Reactome: R-HSA-9027277;Reactome: R-HSA-202433;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-2029485;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-2871809;MetaCyc: PWY-6351 "Inositol phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Generation of second messenger molecules";"DAP12 signaling";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated Ca+2 mobilization";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_017031743.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017025947.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_017021570.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy" XP_017021373.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017029037.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_017034829.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017020907.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017018360.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017031599.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_017026746.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis" XP_017016849.2 10 Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-201688 "Synthesis of PC";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL" XP_041631519.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017025140.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017030553.1 9 MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_017035116.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017028858.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_017020091.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017024061.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_017022406.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017023774.1 40 Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-167242;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-75953;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-72086 "Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"mRNA Capping" XP_017028979.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017030186.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017021408.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_017035606.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_017022333.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310 "HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway" XP_017021499.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602 "Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017023503.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017019668.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017036543.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017026480.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017019907.1 20 Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-7384;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5172;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538 "Neutrophil degranulation";"Propanoate metabolism";"Mitochondrial protein import";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI" XP_017034880.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017032208.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017020845.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017022890.1 3 Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562 "Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria" XP_017031176.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017021773.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017030134.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017034541.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017019607.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_041631048.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017038226.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_017035022.1 7 KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25 "Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism" XP_017027257.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017017999.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017019566.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_041632230.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041631977.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017035574.1 14 MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis" XP_017026376.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_017017678.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_041633416.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_041632202.1 42 Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222 "Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"Meiotic synapsis";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"DNA methylation";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis" XP_017030184.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_041630260.1 4 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism" XP_017028329.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_017021894.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_041631228.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_041631757.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_017034191.1 57 Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425 "APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1" XP_017021045.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017022183.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017025552.1 9 KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00950+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5 "Phenylalanine metabolism";"Tyrosine catabolism";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis" XP_017026733.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017038050.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence" XP_017025874.1 6 Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122 "Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017027495.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017031962.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_017028360.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_017026276.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017038368.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017034418.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017019035.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017035991.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_041630588.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041633152.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017037566.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017029540.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_017027359.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_017025353.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017031606.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017029944.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017018481.1 10 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_017016706.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_041631736.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017029911.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017027893.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017025234.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017019084.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955 "Long-term potentiation";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Ion homeostasis";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_017021249.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017034030.1 19 Reactome: R-HSA-418885;Reactome: R-HSA-8950505;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-389359;Reactome: R-HSA-525793;Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-3928662;Reactome: R-HSA-114604;Reactome: R-HSA-983231;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-2029482 "DCC mediated attractive signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"MAPK6/MAPK4 signaling";"EGFR downregulation";"CD28 dependent Vav1 pathway";"Myogenesis";"Rho GTPase cycle";"RHO GTPases activate IQGAPs";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"EPHB-mediated forward signaling";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"Regulation of actin dynamics for phagocytic cup formation" XP_017034736.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_041632208.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017021371.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017034907.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_041633487.1 6 KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway" XP_017026735.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017022185.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041632957.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017019902.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238 "Neutrophil degranulation";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II" XP_017031034.1 13 MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5690 "Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)" XP_017037534.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017020534.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017029840.1 13 KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902 "Various types of N-glycan biosynthesis";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)" XP_017028801.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017028768.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017022938.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_041631171.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017032921.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276 "SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_041632997.1 42 Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-5250924;Reactome: R-HSA-110331 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"DNA methylation";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"RMTs methylate histone arginines";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Processing of DNA double-strand break ends";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine" XP_017034382.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017019550.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017033711.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017031492.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_017024533.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017036210.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Degradation of DVL";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017024620.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017019648.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017026665.1 13 KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-2161;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;Reactome: R-HSA-196757 "Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Metabolism of folate and pterines" XP_017033781.1 8 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_017034645.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017017696.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017018284.2 14 MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis" XP_017031800.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_017027378.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_017030003.1 10 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-382556;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72731 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP" XP_017029725.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017036366.1 15 Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896 "Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases" XP_017032734.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017020916.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017038064.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418594 "PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (i) signalling events" XP_017033249.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017020974.1 4 MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_017033866.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017030370.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534 "G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4" XP_017027547.1 9 MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6983 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis" XP_017017559.1 10 Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153 "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"mTOR signaling pathway";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Human papillomavirus infection" XP_017037227.1 7 KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;Reactome: R-HSA-1660662;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-7838 "Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis" XP_017021533.1 18 MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7220 "Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_017018610.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017024017.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017022693.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017020953.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017021608.1 11 MetaCyc: PWY-6964;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539 "Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Glutamate and glutamine metabolism" XP_017028202.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_017021602.1 56 Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902 "The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"UCH proteinases";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity" XP_017037107.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569 "Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_017036140.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_017035872.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_017033063.1 22 MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7606;MetaCyc: PWY-7727;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-6958;MetaCyc: PWY-6433;MetaCyc: PWY-7049;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7726 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_017031170.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041630499.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017035933.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_017032122.1 5 MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8 "Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation" XP_017016501.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_041633026.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling" XP_017033549.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017027553.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041631973.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017032212.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017037292.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017019060.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway" XP_017016958.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_017037693.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017029868.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017029608.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017037303.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-6142 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017029924.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017025444.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017018698.1 4 KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_017023119.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" XP_017028269.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017016997.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017036501.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017021763.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684 "Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state" XP_017031177.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017037932.1 8 KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Oxidative phosphorylation";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Photosynthesis";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017020260.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017018109.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359 "Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation" XP_017033924.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017037349.1 6 MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560 "Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Triglyceride catabolism" XP_017029619.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017034033.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-881907;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors" XP_017020537.1 3 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_017025456.1 4 KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50 "Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III";"Cysteine and methionine metabolism" XP_017034481.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017024598.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_017023063.1 10 KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11 "Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis" XP_017018657.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017023441.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017020084.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017027400.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017021942.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_017020161.1 12 MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1 "Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Methane metabolism" XP_017037968.1 5 KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism" XP_017032963.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017022670.1 18 MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4 "Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Linoleic acid metabolism" XP_017031794.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation" XP_017016812.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017028442.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017029985.1 4 MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688 "L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism" XP_017025684.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_041632420.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017018950.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017028314.1 4 KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14 "Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism" XP_017024392.1 6 Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;MetaCyc: PWY-6854 "Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)" XP_017017684.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_017032707.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017023747.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017034621.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017037480.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017023905.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017023992.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017022305.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356 "TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_017022206.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017029128.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-445144 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Synthesis of PC";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1" XP_017031323.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells" XP_017029491.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117 "O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis" XP_017030846.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017038024.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895 "ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency" XP_017027256.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_041631536.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017035345.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300 "Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_017021583.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017034198.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017029784.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_017028556.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_017034713.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_041632030.1 42 Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"Meiotic synapsis";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"DNA methylation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Processing of DNA double-strand break ends" XP_017024112.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017034195.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041631227.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_041631450.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017027362.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017019952.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017020702.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017023035.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359 "Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation" XP_017025118.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017022736.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041633063.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017019083.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946 "Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"RAF activation";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants" XP_017018627.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_017035429.2 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_017025982.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_041630955.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017027255.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017026432.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017029610.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017021183.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017031564.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017037795.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_017037483.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017033592.2 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_017018382.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017017824.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017037530.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017026105.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017033295.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017025275.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017016809.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017028484.1 12 KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817 "Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Stachyose degradation";"Glycogen synthesis";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017023983.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_017025017.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_017030341.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017017503.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_017026418.2 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_017030701.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation" XP_017026721.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_017016320.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017023555.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_017024557.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017029109.1 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" XP_017020052.1 10 MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11 "Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism" XP_017038257.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_041631449.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017024037.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017036601.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017029246.1 8 Reactome: R-HSA-4086398;Reactome: R-HSA-5340588;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-4641263;Reactome: R-HSA-5099900 "Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"Regulation of FZD by ubiquitination";"WNT5A-dependent internalization of FZD4" XP_017026050.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041631170.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_041631224.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017021234.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_041633262.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017025104.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_017033956.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_041632652.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017030237.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017032050.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017025832.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_017035697.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017032850.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_017016445.1 12 Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-73762;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RNA Polymerase I Transcription Initiation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017037587.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154 "Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin" XP_017038059.1 13 KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;Reactome: R-HSA-71384;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00640+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857 "Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Methane metabolism";"Lupulone and humulone biosynthesis";"Ethanol oxidation";"Carbon fixation pathways in prokaryotes";"L-isoleucine biosynthesis V";"Propanoate metabolism";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis" XP_017036939.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN" XP_017029011.1 6 KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Chitin derivatives degradation" XP_017025679.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017023410.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5689880 "Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases" XP_041630732.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017032127.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017023459.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144 "Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" XP_017034692.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017038133.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017023647.1 3 MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_017038195.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017029774.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events" XP_017034165.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017025719.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_017026064.1 8 KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Oxidative phosphorylation";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Photosynthesis";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017033821.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_017025674.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2 "Glutathione metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism" XP_017035614.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017027954.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017024079.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_017026478.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017033881.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_041630833.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017016471.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017024148.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins" XP_017021383.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017020881.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017035748.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017018452.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017030213.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_017038575.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_017021323.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017023651.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_017020905.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017036628.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017031651.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_017024425.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017038564.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_017021959.1 9 MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12;MetaCyc: PWY-6901;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-7003;Reactome: R-HSA-70171 "Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis" XP_041632056.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017027140.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017032895.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017020261.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017038016.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_017037548.1 4 KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_041630641.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017025889.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" XP_017033060.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017020868.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017024987.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017036878.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017019816.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017025131.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017035908.1 8 MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-7179 "Purine deoxyribonucleosides degradation II";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Purine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation I" XP_017025267.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_017034440.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017036429.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017022472.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_041633419.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017038416.1 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017036431.1 12 Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-451308 "Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor" XP_017034277.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017024395.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_017023204.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017024524.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017026747.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_017024996.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-201688 "Synthesis of PC";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL" XP_017025359.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017028266.1 11 Reactome: R-HSA-71403;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7124 "Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)" XP_017022061.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017035868.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_017033417.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017027479.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017028337.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017034891.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_017018800.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017018079.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017026197.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017029768.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017024326.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017035238.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017020143.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_041632737.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017036185.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017033457.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017016858.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_041630828.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017030952.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017032448.2 27 Reactome: R-HSA-975957;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-77595;Reactome: R-HSA-975956;Reactome: R-HSA-8851708;Reactome: R-HSA-159231;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-77588;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-111367 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"snRNP Assembly";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Processing of Intronless Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Signaling by FGFR2 IIIa TM";"Transport of Mature mRNA Derived from an Intronless Transcript";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"SLBP independent Processing of Histone Pre-mRNAs" XP_041630374.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017030174.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017016331.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017035461.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017033853.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017029889.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_017020252.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017030445.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_041631893.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_017038132.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017027491.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017020550.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017020605.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-212676;Reactome: R-HSA-6794361;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-3000170 "Nephrin family interactions";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Syndecan interactions" XP_017020011.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_017017457.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017020073.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017025577.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593 "Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity" XP_017038008.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017036352.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017016696.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017030499.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_041633493.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017023687.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556 "Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Degradation of DVL";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport" XP_017021031.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017018967.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_041631229.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017036339.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-168333 "HCMV Early Events";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_017024239.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_041631589.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017016405.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_017036973.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_017020870.2 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017026631.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_017017777.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017033615.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017036511.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017028430.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017020531.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017031160.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_041631050.1 9 Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_017022157.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017023669.1 15 MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-5723 "Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Rubisco shunt" XP_017022971.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017027099.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017032735.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017035206.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_041630796.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism" XP_017030441.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017024826.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_017027868.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_041631098.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017028764.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017020067.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017018017.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017035803.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017027264.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017030811.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-186763 "EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"Downstream signal transduction" XP_017023634.1 26 Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-983189;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"Cilium Assembly";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic" XP_017022299.1 11 Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-202733;Reactome: R-HSA-3560783 "HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type" XP_017027082.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017031813.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017027308.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs" XP_017021491.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017035999.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_041633218.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017023644.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017027394.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017021752.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017017077.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017035268.1 7 KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-6922;MetaCyc: PWY-4984;MetaCyc: PWY-46;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635 "Arginine and proline metabolism";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Arginine biosynthesis";"Urea cycle" XP_017022761.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017020863.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_041631642.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017016368.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017016618.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_017025798.1 5 Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20 "Neutrophil degranulation";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis" XP_041631150.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8948700 "Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_017034244.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017025573.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017018990.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017018146.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017017453.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017028032.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017018368.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_017020959.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017028984.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_017027081.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_017034028.1 19 Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-389359;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-8950505;Reactome: R-HSA-418885 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"CD28 dependent Vav1 pathway";"Myogenesis";"EGFR downregulation";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"DCC mediated attractive signaling" XP_017026202.1 3 KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45 "Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_017029723.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017036440.1 12 Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-451308 "Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"NrCAM interactions";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor" XP_041631735.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017022336.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_041630801.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017016621.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_017032710.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017035647.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_041630905.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017038339.2 8 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017018593.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041631878.1 3 Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_017016999.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017021307.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017025197.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590 "MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling" XP_017017438.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017031862.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_017028272.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_017028736.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017021296.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017034044.1 4 Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27 "Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation" XP_017018154.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017027307.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633 "O-linked glycosylation";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_017034499.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017036972.1 6 KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_017031986.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017029749.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017025675.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017035489.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017033220.1 30 Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-2644607;Reactome: R-HSA-5684264;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-2122947;Reactome: R-HSA-2565942;Reactome: R-HSA-2894862 "GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Interleukin-1 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017029962.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017017076.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017025235.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_041632506.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017035970.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017025198.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017023989.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_017018255.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017031291.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017019279.1 5 Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-205043 "NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus" XP_017038400.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017023797.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_017034465.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017036430.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-442982 "Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017022418.1 29 Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-112382 "Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex" XP_041633202.1 24 Reactome: R-HSA-444257;Reactome: R-HSA-5625740;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921 "RSK activation";"RHO GTPases activate PKNs";"Thermogenesis";"FCERI mediated NF-kB activation";"Integrin signaling";"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of AKT2";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation" XP_017027266.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017028388.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017038014.1 12 MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-5873;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5870 "Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_017037151.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_017037502.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017023591.1 6 MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6124 "Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II" XP_017030615.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_041631899.1 18 Reactome: R-HSA-5689880;KEGG: 04070+3.1.3.67;KEGG: 05235+3.1.3.16;Reactome: R-HSA-199418;Reactome: R-HSA-1855204;Reactome: R-HSA-8948747;Reactome: R-HSA-5689896;Reactome: R-HSA-1660499;Reactome: R-HSA-202424;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;KEGG: 04660+3.1.3.16;KEGG: 00562+3.1.3.67;Reactome: R-HSA-8948751;MetaCyc: PWY-6368;Reactome: R-HSA-5674404;Reactome: R-HSA-5628897 "Ub-specific processing proteases";"Phosphatidylinositol signaling system";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of the PI3K/AKT network";"Synthesis of IP3 and IP4 in the cytosol";"Regulation of PTEN localization";"Ovarian tumor domain proteases";"Synthesis of PIPs at the plasma membrane";"Downstream TCR signaling";"Th1 and Th2 cell differentiation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"T cell receptor signaling pathway";"Inositol phosphate metabolism";"Regulation of PTEN stability and activity";"3-phosphoinositide degradation";"PTEN Loss of Function in Cancer";"TP53 Regulates Metabolic Genes" XP_017022350.1 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_017021248.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_041632978.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017038067.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017031527.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_017021977.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_041632920.1 10 KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;Reactome: R-HSA-1855191 "Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus" XP_017016774.1 4 Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-6799198 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis" XP_017031747.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation" XP_017031804.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_041631168.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017036907.1 4 MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32 "Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_017038047.1 5 Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5205685;Reactome: R-HSA-983168 "Amyloid fiber formation";"Aggrephagy";"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017037497.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017021357.1 3 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_017037956.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_017027799.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" XP_017038606.1 13 Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-3000171;Reactome: R-HSA-216083 "Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Collagen degradation";"Anchoring fibril formation";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Laminin interactions";"Extracellular matrix organization";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions" XP_017028936.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017017508.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_017035246.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_017025813.1 18 KEGG: 00680+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086 "Methane metabolism";"Gluconeogenesis";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_017021304.1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" XP_017025465.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_017036712.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017038632.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017029782.1 4 MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61 "Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_041632132.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017023477.1 9 Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244 "EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation" XP_017031226.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017028923.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017032845.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_017019665.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041630447.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_017028651.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017036318.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_041632563.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041631758.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_017037622.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017027665.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041633488.1 6 Reactome: R-HSA-975578;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_017030695.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017018595.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041632742.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017037540.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017033858.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_041632776.1 57 Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577 "The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21" XP_017037189.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017025792.1 30 Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-5684264;Reactome: R-HSA-1170546;Reactome: R-HSA-9020702;Reactome: R-HSA-2644607;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-2122947;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-917937;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-2644606 "FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Prolactin receptor signaling";"Interleukin-1 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Iron uptake and transport";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017022092.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017024023.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017018363.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017036683.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041630930.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017029960.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_017025381.1 9 Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection" XP_017018078.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017031243.1 6 Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722 "Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex" XP_017027029.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459 "NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017025423.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695 "Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017016414.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017032126.1 12 MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5870 "Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_017028265.1 11 KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-6549 "Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III" XP_017037274.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017034242.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017033606.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017028862.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_041631821.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017016363.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017021049.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_041632185.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565 "Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Processing of DNA double-strand break ends";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"RMTs methylate histone arginines";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"HCMV Early Events";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017025931.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_041633270.1 5 MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;Reactome: R-HSA-196757 "Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Metabolism of folate and pterines" XP_017020746.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER" XP_017036788.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017032584.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638 "SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins" XP_017028728.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017029269.1 7 KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-6596;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695 "Purine metabolism";"Neutrophil degranulation";"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation" XP_017030783.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_017017680.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_041631803.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017032527.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_017033250.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017018594.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017017024.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_017017953.1 8 KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27 "Pyruvate metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism" XP_041633498.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041632620.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017036304.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017034529.1 6 MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-6922;Reactome: R-HSA-8964539 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism" XP_017034193.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041630762.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041631181.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017029886.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017031783.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017023663.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_017031293.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017028258.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-191859 "HCMV Early Events";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly" XP_017024847.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_041633278.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017017461.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041632044.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017034934.1 20 Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400 "Translesion synthesis by REV1";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Polymerase switching";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER" XP_017025194.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017019034.1 52 Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-76061;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-5250924;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"mRNA Capping";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events" XP_017023940.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017031460.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017029218.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017031512.1 42 Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-9609690;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"Meiotic synapsis";"HCMV Early Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Oxidative Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Processing of DNA double-strand break ends";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence" XP_017027932.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_017032205.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017029988.1 4 Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737 "Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis" XP_017032922.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017035273.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017037773.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017037839.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_017022830.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017022349.1 4 KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_017028601.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017035839.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_041633003.1 42 Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-201722 "Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA methylation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"RMTs methylate histone arginines";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Processing of DNA double-strand break ends";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex" XP_017020178.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_041630417.1 12 Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13 "Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism" XP_017022417.1 29 Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-76042 "RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_017021954.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_017017550.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_017029155.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017028886.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017018553.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017031964.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017031814.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017038592.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017017437.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017033486.1 6 Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261;MetaCyc: PWY-6118 "Triglyceride catabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerol-3-phosphate shuttle" XP_017032060.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017023530.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017037860.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017032080.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Ion channel transport" XP_017026722.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_017025723.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017036446.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017028218.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017038015.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_017031546.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017036249.1 9 KEGG: 00010+1.2.1.12;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70263 "Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Gluconeogenesis" XP_017026263.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_041631645.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017018210.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017031435.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017020965.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017027767.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_041633504.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017017359.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_041633503.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017021739.2 6 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling" XP_041632648.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_017024665.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017023934.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017024161.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017031832.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017023192.1 5 KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661 "Arginine and proline metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation" XP_017024232.1 14 Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Macroautophagy";"Intraflagellar transport";"Aggrephagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_017029841.1 13 Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916 "CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation" XP_017030183.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_017037368.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017033519.1 4 KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism" XP_017017444.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017036438.1 12 Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-8849932 "Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules" XP_017021252.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017037111.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017021204.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017033743.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017018640.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017034422.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017026734.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017033517.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_017017774.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017038398.1 3 Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "Rap1 signalling";"cGMP effects";"Ca2+ pathway" XP_017028540.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_017025438.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041632229.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017029267.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_017032861.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017026694.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-72731 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP" XP_041633173.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017023517.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017025498.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_017028268.1 11 MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7268 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017028821.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017023776.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017022307.1 42 Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-110330;Reactome: R-HSA-201722 "Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PRC2 methylates histones and DNA";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"RMTs methylate histone arginines";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Processing of DNA double-strand break ends";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex" XP_017032149.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_017021059.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041632490.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017016695.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_041631533.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017038141.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_017033997.1 4 KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004 "Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I" XP_017036409.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017018948.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017034073.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017019785.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017019454.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes" XP_017023728.2 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_041632195.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017026289.1 13 Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4061;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18 "Glutathione conjugation";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450" XP_017033978.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017031222.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041631112.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670 "Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"G alpha (i) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway" XP_017021547.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017036239.1 6 Reactome: R-HSA-2426168;Reactome: R-HSA-446199;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+4.1.1.33 "Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" XP_017021050.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_017022017.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events" XP_017034640.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017019499.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD" XP_017029373.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_017017755.1 14 Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-5981 "Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III" XP_017021250.1 5 Reactome: R-HSA-4719360;Reactome: R-HSA-162710;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-162699 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose" XP_017030156.1 26 Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-1234158;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575 "PPARA activates gene expression";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling" XP_041633095.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017026996.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017034689.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017018241.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017035289.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017025237.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017037313.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017022897.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021369.1 21 KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7219;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7224 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage" XP_017019092.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-5673000 "Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"RAF activation" XP_017017428.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017018477.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041631923.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017028722.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017021322.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017036191.1 13 KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416572 "Thermogenesis";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate ROCKs";"EPHB-mediated forward signaling";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Sema4D induced cell migration and growth-cone collapse" XP_041632233.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017019007.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017034616.1 3 MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)" XP_017034641.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017032983.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041631582.1 13 Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-419037 "Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Extracellular matrix organization";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions";"Anchoring fibril formation";"NCAM1 interactions" XP_017038203.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017036343.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602 "Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017017031.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017019930.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017021112.1 3 Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350 "Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism" XP_017037506.1 3 MetaCyc: PWY-7424;KEGG: 00100+2.3.1.26;Reactome: R-HSA-8964038 "Sterol:steryl ester interconversion (yeast)";"Steroid biosynthesis";"LDL clearance" XP_017035019.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017032210.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017018350.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017031543.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_017037017.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017036740.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017026738.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_017036260.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation" XP_017023037.1 4 KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475 "Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_017024658.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017035816.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017028672.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017022773.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017026061.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017037482.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_041632421.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017019783.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017033572.1 10 Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23 "Neutrophil degranulation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Other glycan degradation";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series" XP_017018501.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017031722.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017029453.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017022300.1 11 Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237 "Syndecan interactions";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2" XP_017021006.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710 "Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy" XP_017021013.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017038446.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017025962.1 8 KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Oxidative phosphorylation";"Photosynthesis";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_017021888.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017031228.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_017020459.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017016884.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_017025025.1 18 Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_017020622.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_017032016.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041633248.1 11 MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-3861;MetaCyc: PWY-7456 "Mannitol biosynthesis";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II";"Beta-(1,4)-mannan degradation" XP_041632026.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017018088.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017038230.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Estrogen-dependent gene expression";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_017022937.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017021082.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017016992.1 6 Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616 "Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017022420.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017024722.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017025389.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017021575.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_017033836.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_017031604.1 14 Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-193692 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR" XP_041631839.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017025192.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017019292.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017034068.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017032829.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017034093.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017032943.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017026811.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552 "Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Signaling by Leptin" XP_017036362.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017034789.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041632952.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis" XP_017031812.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041631223.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_041633425.1 5 MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621 "Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine catabolism" XP_017032005.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017027265.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017036393.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017029987.1 4 KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737 "Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis" XP_017025418.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-350562 "Hedgehog ligand biogenesis";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)" XP_017018470.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017020038.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017022295.1 11 Reactome: R-HSA-4420332;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"Retinoid metabolism and transport";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD" XP_017033147.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_041632493.1 4 Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847 "UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones" XP_017030470.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017027735.1 6 MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-2426168 "Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)" XP_041633521.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017027012.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017024885.1 42 Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-5250924;Reactome: R-HSA-110331 "Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"RMTs methylate histone arginines";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Processing of DNA double-strand break ends";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine" XP_017035951.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_017016974.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017022423.1 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" XP_017018055.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017036118.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017036391.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017025248.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017021871.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017020636.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017032598.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017028330.1 3 KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1 "Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway" XP_017029722.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017019311.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017023748.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines" XP_017021872.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017034096.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017028558.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" XP_017025399.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017025114.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_017024664.1 4 KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_017026294.1 13 MetaCyc: PWY-6370;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7112 "Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification" XP_017027229.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017031443.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017037251.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017033673.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017017661.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017032070.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041632167.1 42 Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379 "PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"DNA methylation";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events" XP_017024337.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017028708.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017027376.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017034070.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_041632646.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex" XP_017025828.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017018118.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1 "G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism" XP_017020292.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017028403.1 12 Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484 "Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_017023984.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_017029738.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017030776.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017030340.1 8 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection" XP_017020727.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017030958.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_017021712.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017021789.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_041632701.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017033567.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017022415.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II" XP_017037137.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017033757.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017036090.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017028920.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017031531.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_017037188.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_041632115.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017020973.1 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_017023778.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017032048.1 6 Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403 "Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)" XP_017021152.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_017017949.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017026455.2 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_017022348.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_017025000.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017018721.1 6 KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336 "Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_041633007.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017024601.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017025391.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017034384.1 19 MetaCyc: PWY-7205;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-6545;Reactome: R-HSA-380320;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7176;Reactome: R-HSA-380270;MetaCyc: PWY-7222;MetaCyc: PWY-7198 "CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_017032174.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041633006.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017026173.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041631993.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017029849.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_041630323.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017019126.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017027379.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_041632321.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017027270.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_017025232.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017037871.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017033216.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017027712.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_017020771.1 52 Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-5617472;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-73780;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-76061;Reactome: R-HSA-5601884;Reactome: R-HSA-5250924;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-1834949;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Chain Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Transcriptional regulation by small RNAs";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_017027871.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017037020.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017028826.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017037579.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017034801.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017022550.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_017030887.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_017035869.1 20 MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II" XP_041632485.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017021325.1 12 KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550 "Purine metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfate activation for sulfonation";"Selenate reduction";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se" XP_041631783.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017030343.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017035624.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017037344.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017017514.1 4 Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4 "Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017031507.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041632828.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017023184.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017034283.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017029562.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017036361.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017016912.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017022614.1 7 Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210 "Mitochondrial protein import";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Cristae formation";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling" XP_017037040.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017033238.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_017026369.1 13 KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842 "Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II" XP_017021723.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017038206.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017027145.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_017035243.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_017033351.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017037536.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017028198.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape" XP_017022265.1 57 Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids" XP_017033895.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017030086.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017031298.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_017032501.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017016417.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_017036563.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017018148.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017018489.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017034176.1 10 KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6536;MetaCyc: PWY-6537;MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;MetaCyc: PWY-5022;Reactome: R-HSA-916853;KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19 "Propanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II";"4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation V";"Degradation of GABA";"beta-Alanine metabolism";"Butanoate metabolism" XP_017027031.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-427413 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression" XP_017020049.1 10 MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway" XP_017032816.1 20 Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-69091 "PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Polymerase switching" XP_017033496.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_041633092.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_041633005.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017030924.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017022248.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_017025836.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017028136.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017032109.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017034378.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_017018635.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" XP_017018216.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017026810.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552 "Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin" XP_017031808.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_017038371.1 11 Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"COPI-mediated anterograde transport" XP_017038151.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017036390.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_017028988.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_017034274.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017031563.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017031686.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_017036689.1 22 Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558 "Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_017032207.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017024501.1 11 KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184 "Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Tunicamycin biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_017030993.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_017036454.1 12 Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-447038 "Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"NrCAM interactions" XP_017020546.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_041630861.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041632900.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565 "Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Processing of DNA double-strand break ends";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"RMTs methylate histone arginines";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"HCMV Early Events";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"DNA methylation";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017036706.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041632822.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs" XP_017037631.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017034871.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017037503.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017021943.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_017021105.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" XP_041631049.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017032893.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017017660.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017020386.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_017032599.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017026252.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" XP_017023749.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines" XP_017020375.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017026109.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017018215.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041630895.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_017021358.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017024099.1 3 KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129 "Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)" XP_017035961.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7117 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_017038005.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017019925.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_017020669.1 4 MetaCyc: PWY-6823;MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12 "Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_017032170.1 6 Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3 "Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism" XP_017030715.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041630370.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017032169.1 33 MetaCyc: PWY-3162;MetaCyc: PWY-1801;KEGG: 00626+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-6333;MetaCyc: PWY-5078;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-6313;MetaCyc: PWY-7111;MetaCyc: PWY-6587;MetaCyc: PWY-5057;MetaCyc: PWY-7798;MetaCyc: PWY-6802;KEGG: 00071+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00260+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-6871;MetaCyc: PWY-5079;MetaCyc: PWY-5751;MetaCyc: PWY-7396;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00680+1.1.1.284;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6342 "L-tryptophan degradation V (side chain pathway)";"Formaldehyde oxidation II (glutathione-dependent)";"Naphthalene degradation";"Metabolism of xenobiotics by cytochrome P450";"L-leucine degradation III";"Acetaldehyde biosynthesis I";"L-isoleucine degradation II";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to ethanol II";"Retinol metabolism";"L-methionine degradation III";"Serotonin degradation";"Pyruvate fermentation to isobutanol (engineered)";"Pyruvate fermentation to ethanol III";"L-valine degradation II";"Protein S-nitrosylation and denitrosylation";"Salidroside biosynthesis";"Fatty acid degradation";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Glycine, serine and threonine metabolism";"Ethanol oxidation";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Phenylethanol biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"Tyrosine metabolism";"Pyruvate fermentation to ethanol I";"Methane metabolism";"Chloroalkane and chloroalkene degradation";"(S)-propane-1,2-diol degradation";"Drug metabolism - cytochrome P450";"Noradrenaline and adrenaline degradation" XP_041631522.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_017021889.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017024718.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017025730.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017018409.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_017027198.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017016725.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_017030216.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_017037643.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Neutrophil degranulation";"Peroxisomal protein import" XP_017025026.1 18 Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167246 "HIV elongation arrest and recovery";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_017035240.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_017036509.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017030158.1 26 Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-918233 "RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"TRAF3-dependent IRF activation pathway" XP_017031555.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017027290.1 14 MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4 "Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism" XP_017028986.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_017031086.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692 "HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"Regulation of MECP2 expression and activity" XP_017020351.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_017026542.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_017023314.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017029671.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017022361.2 1 Reactome: R-HSA-1296061 "HCN channels" XP_017027922.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017021586.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_017032987.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017023609.1 26 Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-4615885;Reactome: R-HSA-5696400;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-1362277;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-8866654;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-110314 "Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"SUMOylation of DNA replication proteins";"Dual Incision in GG-NER";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Transcription of E2F targets under negative control by DREAM complex";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"E3 ubiquitin ligases ubiquitinate target proteins";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex" XP_017034272.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017016941.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017036604.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017023572.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_017027470.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_017026962.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017027998.1 24 KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-444257;Reactome: R-HSA-5625740;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"Activation of AKT2";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Integrin signaling";"RSK activation";"RHO GTPases activate PKNs";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway" XP_017028922.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017023506.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017036895.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017025942.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_017035648.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_017035048.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716 "AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin" XP_017026612.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_041632905.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017023962.1 25 Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-380270;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids" XP_017025665.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis" XP_017034284.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017016820.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017034532.2 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017027097.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017022016.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events" XP_017031355.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017036122.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017035877.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_017036375.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017033397.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_017030450.1 10 MetaCyc: PWY-5844;MetaCyc: PWY-7996;MetaCyc: PWY-5895;MetaCyc: PWY-5892;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-5891;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163 "Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_041632016.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017034699.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_017029643.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-375165 "Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"Neutrophil degranulation";"NCAM signaling for neurite out-growth" XP_017036128.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017035294.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism" XP_017030492.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017023224.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041630713.1 5 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017017558.1 10 KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;Reactome: R-HSA-1660499 "mTOR signaling pathway";"3-phosphoinositide biosynthesis";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane" XP_017020604.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017034251.1 29 Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-427413 "Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_017023318.1 5 MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614 "Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage" XP_017025990.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017036787.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_017029374.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_017037867.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017034300.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_041632879.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_041630798.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017019294.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017034586.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_017036443.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982 "Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017022754.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_017038054.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128 "Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling" XP_017022538.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017034392.1 5 Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_017030026.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017023805.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_041633249.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017022549.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_017028539.1 5 MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_017035699.1 8 KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-6609 "Purine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Adenine and adenosine salvage III" XP_017032086.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_017029287.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017020721.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017018362.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017027141.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017017597.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017028380.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017035059.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676 "Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_017017519.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017031610.1 13 MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403 "TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citric acid cycle (TCA cycle)" XP_017034294.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017038270.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017028910.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017027228.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017037677.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017031248.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017017459.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017027696.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017036413.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_041633447.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017032687.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017025188.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017025107.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017028427.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017019642.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_041633436.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803211 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_017037821.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017025991.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017018472.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017035841.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_017037019.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017023652.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_017019484.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_041632172.1 42 Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118 "B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"DNA methylation" XP_017020020.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722 "Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_017028925.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017036172.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_017034034.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017029495.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" XP_017029884.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017021478.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017023195.1 5 KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661 "Arginine and proline metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation" XP_017023775.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017036571.1 11 Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082 "Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression" XP_017023450.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017020464.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_017028285.1 3 MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315 "Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol" XP_041633062.1 29 Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-167246 "mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript" XP_017034434.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017036677.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-190861 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Recycling pathway of L1";"Gap junction assembly" XP_017037869.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017019956.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837 "Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation" XP_017020730.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017026970.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_017025191.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_041630373.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017018612.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_017036433.1 12 Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-451308 "Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor" XP_017030807.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-186763 "EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"Downstream signal transduction" XP_017034810.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017022611.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041633502.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017035279.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017022554.1 6 Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693 "Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling" XP_017016956.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017037823.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017033627.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017037143.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017027340.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017025683.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017033083.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017028005.1 24 Reactome: R-HSA-2871837;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-5625740;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5218921;Reactome: R-HSA-2730905 "FCERI mediated NF-kB activation";"Integrin signaling";"Downstream TCR signaling";"RHO GTPases activate PKNs";"RSK activation";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"VEGFR2 mediated cell proliferation";"Role of LAT2/NTAL/LAB on calcium mobilization" XP_017036947.1 29 Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response" XP_017025911.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017024825.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_041632659.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017033040.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017035593.1 9 MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation" XP_017037170.1 7 MetaCyc: PWY-7039;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4 "Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Synthesis of PA";"Synthesis of PG";"Choline biosynthesis III";"Ether lipid metabolism" XP_041633501.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017035247.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017023567.1 13 Reactome: R-HSA-5674135;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802948 "MAP2K and MAPK activation";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Relaxin signaling pathway";"Signaling by BRAF and RAF fusions";"Human papillomavirus infection";"Signaling by high-kinase activity BRAF mutants" XP_017020466.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_017020964.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_041631523.1 8 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_017023008.1 5 MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7919;Reactome: R-HSA-4793954 "Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)" XP_017023384.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11 "Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism" XP_017038397.1 3 Reactome: R-HSA-4086398;Reactome: R-HSA-392517;Reactome: R-HSA-418457 "Ca2+ pathway";"Rap1 signalling";"cGMP effects" XP_017024779.1 3 Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_017018818.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017026509.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017021585.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_017031480.1 8 MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391 "Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)" XP_041632878.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017030461.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017018620.1 2 Reactome: R-HSA-2393930;MetaCyc: PWY-8061 "Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification II" XP_041632733.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017018260.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_041632186.1 42 Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-212300;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-4551638 "Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Oxidative Stress Induced Senescence";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PRC2 methylates histones and DNA";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of chromatin organization proteins" XP_017026261.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017023791.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017036201.1 14 MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;KEGG: 00460+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-181;KEGG: 00670+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3661;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1 "Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Cyanoamino acid metabolism";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Metabolism of folate and pterines";"Photorespiration ";"One carbon pool by folate";"Folate transformations I";"Glycine betaine degradation I";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism" XP_017022511.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017036256.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin" XP_041631928.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017025965.1 13 KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7184 "Purine metabolism";"Pyrimidine metabolism";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_017034783.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017029131.1 10 Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903 "Regulation of PTEN stability and activity";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy" XP_017036138.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017017815.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_017026857.1 5 Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3 "Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism" XP_017028724.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017032846.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_017037669.1 5 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation" XP_017027000.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017034681.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017025578.1 6 MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7077;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25 "D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism" XP_017027870.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017028428.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017025997.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017020098.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017028068.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017035673.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017037185.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017029065.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017024699.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017035728.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017025961.1 8 KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Oxidative phosphorylation";"Photosynthesis";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_017027231.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017032171.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017037531.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017037525.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017030982.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017025117.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids" XP_017030248.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling" XP_017034943.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017029032.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017029990.1 4 MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688 "(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism" XP_017020227.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_041631310.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017021085.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017036828.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974 "Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA" XP_017018144.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017034612.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017023694.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017033061.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017038090.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-7383;MetaCyc: PWY-8040 "D-Alanine metabolism";"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis" XP_017027137.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041631075.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017026308.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017027601.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017028577.1 17 Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017022302.1 11 Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-4420332 "Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Retinoid metabolism and transport";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_017016409.1 22 MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7726;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-7035;MetaCyc: PWY-7053;MetaCyc: PWY-5080 "Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_017018548.1 10 MetaCyc: PWY-5497;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-3841;Reactome: R-HSA-196757 "Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Metabolism of folate and pterines" XP_017036752.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017024700.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017031173.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017029609.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017019638.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017036402.1 5 Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_017033908.1 6 KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900 "Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_017027928.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017021527.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017035729.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017022669.1 18 Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803 "Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing" XP_017028720.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017032908.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017028521.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017035445.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017025829.2 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_017021043.1 5 Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20 "Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Folate transformations I";"One carbon pool by folate" XP_017029729.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017036956.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017035639.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_041632135.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017033252.1 14 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" XP_017021665.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017032209.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017031304.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017035594.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_017031687.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017023611.1 52 Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-73863 "Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination" XP_017025622.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017019089.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-877300 "Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF activation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling" XP_017027482.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_017029914.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017034658.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_041630259.1 4 Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis of PC" XP_041632018.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017021032.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017028487.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017038402.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017025037.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017036723.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017025534.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017038572.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017024930.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017033995.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism" XP_041630728.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017035903.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041631794.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017037378.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017029015.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017018730.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_041631014.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017035900.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017033597.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017029545.1 11 MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2 "L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis" XP_017027326.1 7 KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2 "D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis" XP_017035585.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II" XP_017018359.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041631032.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017016850.2 10 Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191 "WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Synthesis of PC" XP_041632414.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017019770.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017034935.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" XP_017022407.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017020037.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017038566.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017019992.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_017027487.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017026493.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017025826.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017030261.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_017026098.1 3 MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141 "Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_017019686.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_017024525.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017028791.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_041631481.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017020431.1 3 KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801 "Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)" XP_017026525.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017029967.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017036606.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017018149.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_041632740.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017029956.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017024560.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_017026030.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017037481.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017031360.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017029984.1 4 MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism" XP_017035907.1 8 MetaCyc: PWY-7179;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1 "Purine deoxyribonucleosides degradation I";"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II" XP_017028315.1 4 KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963 "Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I" XP_017037972.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017033398.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_017020004.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_017037627.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017030175.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017034611.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017024904.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_017019701.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017025390.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017037621.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017034826.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017016324.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021562.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021479.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017018134.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_041631368.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_017026041.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017017010.2 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017035395.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017016697.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_041632633.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017028934.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017018040.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_017027289.1 14 KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-4419969 "Ether lipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PC";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina" XP_017016868.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017022524.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_017033309.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_041630593.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017019278.1 10 KEGG: 00510+2.4.1.83;MetaCyc: PWY-7661;MetaCyc: PWY-7922;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-913709;MetaCyc: PWY-7921;Reactome: R-HSA-4719360;MetaCyc: PWY-7979;Reactome: R-HSA-162699 "N-Glycan biosynthesis";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"O-linked glycosylation of mucins";"Protein O-mannosylation I (yeast)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose" XP_017028030.1 7 KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-2151201 "Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Photosynthesis";"Mitochondrial protein import";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_017028513.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell" XP_017036715.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017033278.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276 "Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways" XP_017030884.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017030777.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017037145.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017025571.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531 "SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus" XP_017019894.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017016553.1 14 MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7254;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-3781 "TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)" XP_017027306.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017026386.1 9 Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex" XP_017020228.2 6 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs" XP_017032175.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_017035061.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610787 "PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state" XP_017034241.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_041631828.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017031843.2 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017023998.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017017348.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017032101.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_041632723.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017028454.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017027201.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_041631864.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017033487.1 6 MetaCyc: PWY-4261;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952 "Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation" XP_017025324.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_017035965.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_017029647.1 15 Reactome: R-HSA-9665246;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-9665247;Reactome: R-HSA-9652282;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-9665233;Reactome: R-HSA-9665251;Reactome: R-HSA-1227986;Reactome: R-HSA-9665244;Reactome: R-HSA-1236382;Reactome: R-HSA-9634285;Reactome: R-HSA-5637810;Reactome: R-HSA-9665250 "Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Drug-mediated inhibition of ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to lapatinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to AEE788" XP_017035062.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720 "Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_017034787.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017018073.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017018483.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_017017080.1 6 KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_017018046.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017032164.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017027918.1 9 MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-8086;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism" XP_017037129.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_017016447.1 7 MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-5659 "Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis" XP_017030659.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_017034313.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017024016.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017017775.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017036643.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017024060.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_041632651.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_041631743.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017038646.1 29 Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-73762 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation" XP_017029531.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041630262.1 4 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin" XP_017035215.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017033925.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017030675.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_017038190.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017030891.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017034377.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447 "RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria" XP_017029890.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_017033029.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017022337.1 11 Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631 "RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility" XP_017024082.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949 "Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA" XP_017037161.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017017931.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017020257.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017022196.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017025819.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017027095.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017027139.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017032013.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017031780.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017026427.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017031609.1 13 MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-6969 "Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_017019503.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_017018066.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017028564.1 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_017020774.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017025621.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion" XP_017029102.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017023194.1 5 Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88 "Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism" XP_041631180.1 7 MetaCyc: PWY-7221;Reactome: R-HSA-6794361;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-3000170;Reactome: R-HSA-373753;Reactome: R-HSA-212676 "Guanosine ribonucleotides de novo biosynthesis";"Neurexins and neuroligins";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Syndecan interactions";"Nephrin family interactions";"Dopamine Neurotransmitter Release Cycle" XP_017016801.1 7 Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064 "Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine catabolism" XP_017026357.1 14 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6796648 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes" XP_041631879.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" XP_017024632.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017028070.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017033879.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017035433.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_017018499.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017029628.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_017034416.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017032454.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017036785.1 4 MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803 "Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing" XP_041632232.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041632732.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_017021000.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_017022494.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017017589.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041630519.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis" XP_017031588.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912 "AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane" XP_041632614.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017037140.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017019639.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017026248.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017023631.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_041630518.1 52 Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-5578749;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-76061;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-5250924;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-427413 "Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"Transcriptional regulation by small RNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"mRNA Capping";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression" XP_017020473.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017019644.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017020083.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017033583.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_041632152.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017028799.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_041631451.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017028570.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin" XP_017027775.1 15 Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Meiotic recombination";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_017021567.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic" XP_017020173.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_041633259.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_017032111.1 5 MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" XP_017020114.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017022883.1 7 MetaCyc: PWY-6610;MetaCyc: PWY-7807;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;MetaCyc: PWY-6605;Reactome: R-HSA-74217;Reactome: R-HSA-6798695 "Adenine salvage";"Glyphosate degradation III";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Adenine and adenosine salvage II";"Purine salvage";"Neutrophil degranulation" XP_017029917.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_041633061.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017037958.1 5 Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783 "Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome" XP_017038140.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_017038559.1 10 Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004 "Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_017021027.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017028692.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_017026866.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017018611.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" XP_017017636.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017037532.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017027410.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930 "G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor" XP_017020536.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis" XP_017024237.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017021068.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017019963.1 17 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6790901 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol" XP_017018670.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017037816.1 13 Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-4341670;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23 "HS-GAG degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Defective NEU1 causes sialidosis";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosaminoglycan degradation" XP_017036586.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017027331.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_017019510.1 5 MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7185 "UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I" XP_017027544.1 30 Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-2564830;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73863 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"Cytosolic iron-sulfur cluster assembly";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase I Transcription Termination" XP_041632117.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_041631906.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017026754.1 4 MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_017034203.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_017017366.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017028727.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017018684.1 8 KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1 "Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism" XP_017019628.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017036646.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361 "Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins" XP_017032515.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017029959.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_041632205.1 42 Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379 "PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PRC2 methylates histones and DNA";"HCMV Early Events";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events" XP_017025300.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017018791.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017029568.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_017019909.1 19 KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5172;MetaCyc: PWY-5913;Reactome: R-HSA-75105;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;Reactome: R-HSA-6798695;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5 "C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes" XP_017027025.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459 "NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_041630730.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017033093.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017031591.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017038332.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_041631336.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017032211.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017019244.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017019253.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017031717.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017020233.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017038149.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_017032562.1 18 KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051 "Linoleic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I" XP_041630507.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017030030.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_017033935.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling" XP_017031861.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_041632119.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017036406.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017024312.1 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017027006.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_017036142.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017022151.1 9 KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-7411 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)" XP_017022070.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021646.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017018223.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017025031.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017032549.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017024359.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_017021470.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017035173.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017027579.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602 "Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017025632.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017021584.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_041632703.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017017689.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017028898.1 2 KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270 "Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate" XP_017027768.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_017038405.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis" XP_017031872.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017033084.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017029843.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167162 "RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape" XP_017018592.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_041631225.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017031253.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017028863.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017026270.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017021945.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017020671.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_017025722.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_041632710.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017036859.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_041630857.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017035364.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017026981.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017027045.1 23 Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-418555 "G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"Ca2+ pathway";"G alpha (s) signalling events" XP_017025705.1 1 Reactome: R-HSA-419771 "Opsins" XP_017033869.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7726 "alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_017019962.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_017016454.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017034993.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_017019597.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017037909.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_017017667.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_041632616.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017036974.1 6 KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway" XP_017024273.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017031367.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017038492.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017029721.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017019546.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_017034738.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017019637.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017036365.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017017526.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017030522.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017031181.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017026430.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017032172.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017035349.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_017029060.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017022775.1 8 Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-5099900 "Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4" XP_017034790.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017036357.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_017024872.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017021096.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017038202.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017018147.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017035235.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017035353.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017035150.1 5 KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937 "Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Iron uptake and transport" XP_017021022.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017022130.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017019095.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-6802952 "Ion homeostasis";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions" XP_017016864.1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091 "Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells" XP_017038281.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_041631174.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017028871.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_041632833.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_017018053.1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630 "Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3" XP_017016908.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017023443.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017025627.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017023196.1 5 Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88 "Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Arginine and proline metabolism" XP_017016402.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017022771.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport" XP_017019490.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017031317.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_017026671.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017032099.1 4 KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis" XP_017031054.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017021714.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017033658.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017027234.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017017025.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017029192.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_041633172.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017032081.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111459 "TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage" XP_017020040.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442 "ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs" XP_017017822.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_041631641.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017029872.1 3 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" XP_017025568.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation" XP_017038120.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017031549.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017019519.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017020309.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017035715.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017030180.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_017025682.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017017876.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017026885.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_017016391.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017028191.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017019460.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_017028926.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017035120.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs" XP_041631637.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_041631624.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017025317.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017023780.1 7 Reactome: R-HSA-5633231;MetaCyc: PWY-6385;MetaCyc: PWY-5265;MetaCyc: PWY-6470;Reactome: R-HSA-446193;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" XP_017026374.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017028312.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017034369.1 3 KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" XP_017036451.1 8 Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;MetaCyc: PWY-7221 "Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis" XP_017024951.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017028505.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_017019513.1 5 MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7185 "UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I" XP_017029754.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_041632029.1 42 Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-5250924;Reactome: R-HSA-110331 "Oxidative Stress Induced Senescence";"DNA methylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Early Events";"RMTs methylate histone arginines";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Processing of DNA double-strand break ends";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine" XP_017021129.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_017028895.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_041632116.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017023340.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_017028559.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_017026632.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017020006.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_017034757.1 5 KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;Reactome: R-HSA-174403 "Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling" XP_017028291.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017028914.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017025882.1 182 Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-975957;Reactome: R-HSA-937042;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-209543;Reactome: R-HSA-382556;Reactome: R-HSA-5675221;Reactome: R-HSA-182971;Reactome: R-HSA-975144;Reactome: R-HSA-9613829;Reactome: R-HSA-912631;Reactome: R-HSA-8856825;Reactome: R-HSA-936440;Reactome: R-HSA-3134975;Reactome: R-HSA-162588;Reactome: R-HSA-4608870;Reactome: R-HSA-2672351;Reactome: R-HSA-72689;Reactome: R-HSA-349425;Reactome: R-HSA-2122948;Reactome: R-HSA-187577;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-6781823;Reactome: R-HSA-1236382;Reactome: R-HSA-110320;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-174490;Reactome: R-HSA-6781827;Reactome: R-HSA-5362768;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6782210;Reactome: R-HSA-2173795;Reactome: R-HSA-5689901;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-901032;Reactome: R-HSA-5689877;Reactome: R-HSA-174113;Reactome: R-HSA-9033241;Reactome: R-HSA-917937;Reactome: R-HSA-69601;Reactome: R-HSA-5357905;Reactome: R-HSA-5689896;Reactome: R-HSA-2871837;Reactome: R-HSA-936964;Reactome: R-HSA-2467813;Reactome: R-HSA-6783310;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-2691232;Reactome: R-HSA-9645460;Reactome: R-HSA-5687128;Reactome: R-HSA-5685942;Reactome: R-HSA-201681;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-3785653;Reactome: R-HSA-195253;Reactome: R-HSA-8863795;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-8875360;Reactome: R-HSA-5610785;Reactome: R-HSA-1799339;Reactome: R-HSA-8849469;Reactome: R-HSA-5676590;Reactome: R-HSA-5696400;Reactome: R-HSA-2173796;Reactome: R-HSA-2173791;Reactome: R-HSA-2979096;Reactome: R-HSA-1236974;Reactome: R-HSA-9013973;Reactome: R-HSA-68827;Reactome: R-HSA-72702;Reactome: R-HSA-1358803;Reactome: R-HSA-4641258;Reactome: R-HSA-2173788;Reactome: R-HSA-168927;Reactome: R-HSA-156827;Reactome: R-HSA-975110;Reactome: R-HSA-4641263;Reactome: R-HSA-9633012;Reactome: R-HSA-5656121;Reactome: R-HSA-174178;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-110312;Reactome: R-HSA-5357956;Reactome: R-HSA-6791226;Reactome: R-HSA-168928;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-8866652;Reactome: R-HSA-174154;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-450321;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-179409;Reactome: R-HSA-75815;Reactome: R-HSA-2408557;Reactome: R-HSA-5696395;Reactome: R-HSA-1253288;Reactome: R-HSA-5693607;Reactome: R-HSA-68949;Reactome: R-HSA-174048;Reactome: R-HSA-1234176;Reactome: R-HSA-5654726;Reactome: R-HSA-6804756;Reactome: R-HSA-5654733;Reactome: R-HSA-9615710;Reactome: R-HSA-8866654;Reactome: R-HSA-8948751;Reactome: R-HSA-977225;Reactome: R-HSA-8876493;Reactome: R-HSA-69541;Reactome: R-HSA-5654732;Reactome: R-HSA-205043;Reactome: R-HSA-5689880;Reactome: R-HSA-400253;Reactome: R-HSA-5358346;Reactome: R-HSA-3322077;Reactome: R-HSA-2559585;Reactome: R-HSA-5656169;Reactome: R-HSA-175474;Reactome: R-HSA-6807004;Reactome: R-HSA-9013507;Reactome: R-HSA-8948747;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-450302;Reactome: R-HSA-5684264;Reactome: R-HSA-1295596;Reactome: R-HSA-5689603;Reactome: R-HSA-2894862;Reactome: R-HSA-917729;Reactome: R-HSA-9646399;Reactome: R-HSA-5607761;Reactome: R-HSA-110314;Reactome: R-HSA-5675482;Reactome: R-HSA-72764;Reactome: R-HSA-6804757;Reactome: R-HSA-5696397;Reactome: R-HSA-532668;Reactome: R-HSA-5607764;Reactome: R-HSA-9636383;Reactome: R-HSA-3769402;Reactome: R-HSA-168638;Reactome: R-HSA-5654727;Reactome: R-HSA-209560;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-9637628;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-6804760;Reactome: R-HSA-937041;Reactome: R-HSA-450408;Reactome: R-HSA-937039;Reactome: R-HSA-5205685;Reactome: R-HSA-2122947;Reactome: R-HSA-8856828;Reactome: R-HSA-192823;Reactome: R-HSA-5696394 "Translesion synthesis by POLK";"Dual incision in TC-NER";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"IRAK2 mediated activation of TAK1 complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"p75NTR recruits signalling complexes";"ABC-family proteins mediated transport";"Negative regulation of MAPK pathway";"EGFR downregulation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Chaperone Mediated Autophagy";"Regulation of signaling by CBL";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of innate immune responses to cytosolic DNA";"Budding and maturation of HIV virion";"Asymmetric localization of PCP proteins";"Stimuli-sensing channels";"Formation of a pool of free 40S subunits";"Autodegradation of the E3 ubiquitin ligase COP1";"Activated NOTCH1 Transmits Signal to the Nucleus";"SCF(Skp2)-mediated degradation of p27/p21";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Formation of TC-NER Pre-Incision Complex";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Translesion Synthesis by POLH";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Membrane binding and targetting of GAG proteins";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Metalloprotease DUBs";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"ER Quality Control Compartment (ERQC)";"Josephin domain DUBs";"SCF-beta-TrCP mediated degradation of Emi1";"Peroxisomal protein import";"Iron uptake and transport";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TNFR1 signaling";"Ovarian tumor domain proteases";"FCERI mediated NF-kB activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Separation of Sister Chromatids";"Fanconi Anemia Pathway";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Alpha-protein kinase 1 signaling pathway";"MAPK6/MAPK4 signaling";"HDR through Homologous Recombination (HRR)";"TCF dependent signaling in response to WNT";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"Myoclonic epilepsy of Lafora";"Degradation of beta-catenin by the destruction complex";"Downregulation of ERBB2 signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"InlB-mediated entry of Listeria monocytogenes into host cell";"GLI3 is processed to GLI3R by the proteasome";"SRP-dependent cotranslational protein targeting to membrane";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"NIK-->noncanonical NF-kB signaling";"Dual Incision in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"ER-Phagosome pathway";"TICAM1-dependent activation of IRF3/IRF7";"CDT1 association with the CDC6:ORC:origin complex";"Ribosomal scanning and start codon recognition";"Downregulation of ERBB2:ERBB3 signaling";"Degradation of DVL";"Downregulation of TGF-beta receptor signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"L13a-mediated translational silencing of Ceruloplasmin expression";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of FZD by ubiquitination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translesion synthesis by POLI";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Translesion synthesis by REV1";"TNFR1-induced NFkappaB signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin-dependent degradation of Cyclin D";"Selenocysteine synthesis";"Formation of Incision Complex in GG-NER";"Downregulation of ERBB4 signaling";"Processing of DNA double-strand break ends";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of FGFR1 signaling";"Regulation of TP53 Activity through Phosphorylation";"Negative regulation of FGFR4 signaling";"Late endosomal microautophagy";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of PTEN stability and activity";"Amyloid fiber formation";"InlA-mediated entry of Listeria monocytogenes into host cells";"Stabilization of p53";"Negative regulation of FGFR3 signaling";"NRIF signals cell death from the nucleus";"Ub-specific processing proteases";"Circadian Clock";"Hedgehog ligand biogenesis";"Glycogen synthesis";"Oncogene Induced Senescence";"Termination of translesion DNA synthesis";"Assembly Of The HIV Virion";"Negative regulation of MET activity";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of PTEN localization";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"activated TAK1 mediates p38 MAPK activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Spry regulation of FGF signaling";"UCH proteinases";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Aggrephagy";"Dectin-1 mediated noncanonical NF-kB signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of necroptotic cell death";"Eukaryotic Translation Termination";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"CLEC7A (Dectin-1) signaling";"Prevention of phagosomal-lysosomal fusion";"Deactivation of the beta-catenin transactivating complex";"NOD1/2 Signaling Pathway";"Negative regulation of FGFR2 signaling";"NF-kB is activated and signals survival";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Modulation by Mtb of host immune system";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of TP53 Activity through Methylation";"IKK complex recruitment mediated by RIP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"IRAK1 recruits IKK complex";"Pink/Parkin Mediated Mitophagy";"NOTCH1 Intracellular Domain Regulates Transcription";"Clathrin-mediated endocytosis";"Viral mRNA Translation";"DNA Damage Recognition in GG-NER" XP_017027661.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017020607.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017035891.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017019624.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017020160.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_041631894.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017034254.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017037931.1 5 MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6 "UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism" XP_017027947.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017023312.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017035295.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism" XP_017034278.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017025835.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017029542.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_017027180.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017028528.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_017026092.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017022865.1 3 Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562 "Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria" XP_017019047.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017019094.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Long-term potentiation" XP_017016954.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_017027866.1 10 KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;MetaCyc: PWY-7849;Reactome: R-HSA-3000171 "Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Amyloid fiber formation";"Neutrophil degranulation";"Urate conversion to allantoin I";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions" XP_017024940.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017027151.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_017035712.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017021887.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017018976.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_017019965.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017020062.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447 "RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria" XP_017029816.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017023850.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017023164.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017020963.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017022373.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017035500.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017023052.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism" XP_041631762.1 4 Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism" XP_017021455.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-8957275 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation" XP_017020279.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017028386.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017027399.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041631424.1 11 MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549 "Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III" XP_017035174.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017036957.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_017033570.1 10 KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695 "Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"MPS VII - Sly syndrome";"Other glycan degradation";"HS-GAG degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Neutrophil degranulation" XP_017019545.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_017023494.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_041632840.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_017034194.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017020376.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017034066.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017031121.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_017016401.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017027260.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017022362.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017023793.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_017023084.1 7 Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214 "AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs" XP_041633031.1 10 Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017032007.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017023206.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017020958.1 17 MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6 "Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism" XP_017028721.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017019482.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017016381.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017018476.1 12 KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13 "Pentose phosphate pathway";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis" XP_017034602.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017034395.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017032475.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017027259.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017028671.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_017027921.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017025507.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_041632654.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017028151.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017033799.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017016760.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017027476.2 4 Reactome: R-HSA-9031525;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8866427 "NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"VLDLR internalisation and degradation" XP_017028816.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_041631077.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017027747.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017018534.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017019036.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017028767.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017036010.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017021186.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017036119.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017019242.1 17 Reactome: R-HSA-5693607;Reactome: R-HSA-69601;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1 "Processing of DNA double-strand break ends";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"mTOR signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Human papillomavirus infection";"Relaxin signaling pathway";"Signaling by SCF-KIT";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis" XP_017037672.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017036890.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017020506.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_017034756.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017029535.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017031161.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_041631976.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041630800.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_041632996.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017034588.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_041632771.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017021312.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_017034432.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017034737.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017024265.1 8 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases" XP_017016976.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017018175.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017034279.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017031889.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017025673.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017027439.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017031004.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017029753.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017031554.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017038236.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017025424.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649 "Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation" XP_017023959.1 6 Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-73930 "Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" XP_017019830.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017019758.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916 "Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation" XP_017030299.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017029497.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" XP_017036870.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017033657.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017034483.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017027282.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017038466.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017034235.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017019093.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Ion homeostasis";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation" XP_041630901.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017030181.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_017030010.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_017029114.1 7 Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-381033;Reactome: R-HSA-114608 "PERK regulates gene expression";"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation" XP_017038647.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017033569.1 10 KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695 "Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"HS-GAG degradation";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation" XP_041632831.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_017023313.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017034525.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_017028320.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017026917.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017016482.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017037485.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017033202.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017027188.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017024378.1 6 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-76005 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+" XP_017034303.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_017033330.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017031129.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017030951.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017026803.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_017038000.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017023690.1 5 MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine catabolism" XP_017027753.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017028928.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017037791.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017033406.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation" XP_017035302.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017024277.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_017022296.1 11 Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783 "HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Syndecan interactions";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type" XP_017029663.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_017034904.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_017027471.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017025956.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017035993.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017032826.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017031124.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017017986.1 9 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol" XP_017036135.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017028723.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017038454.1 18 MetaCyc: PWY-5532;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;KEGG: 00760+2.4.2.1;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-7179;MetaCyc: PWY-4202;Reactome: R-HSA-73614;MetaCyc: PWY-6620;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.3;MetaCyc: PWY-7179-1 "Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Purine metabolism";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Purine deoxyribonucleosides degradation I";"Arsenate detoxification I (mammalian)";"Pyrimidine salvage";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II" XP_017032516.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_041632677.1 42 Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-5250924 "DNA methylation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RMTs methylate histone arginines";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression" XP_017035060.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-983231 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production" XP_017017593.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_017036969.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017030513.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017022180.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041633500.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017038635.1 56 Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815 "APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Degradation of DVL";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D" XP_017037071.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_017030619.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017031537.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_017025367.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017020162.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_017024734.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017033822.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017036735.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_017023522.1 5 MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017023664.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_017036942.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_017038562.1 10 Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-6901 "Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation" XP_017033883.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017024309.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_041633147.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2 "Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism" XP_017027263.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017026675.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017026825.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017026892.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017037142.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017031643.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017016759.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" XP_017023060.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017027469.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017038453.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017033872.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017038491.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017022831.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017021582.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_017027964.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017036893.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_017032984.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041630759.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017037298.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017025032.1 14 MetaCyc: PWY-6728;MetaCyc: PWY-7279;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-3781;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561 "Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_017035745.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017030908.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_041630862.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017023319.1 5 KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532 "Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)" XP_041631678.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate" XP_017017509.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017034454.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_017025291.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017020969.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017017469.1 11 Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167238 "Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_017032788.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017023971.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017037000.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017038117.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_041631335.1 4 KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_017031459.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017032113.1 5 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)" XP_041633096.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017036759.1 5 Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558 "RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_017025744.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017037347.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017034419.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017022870.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_041632815.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017028144.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_017021055.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017023796.1 18 Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409 "Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_017020224.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017034221.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017020364.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590 "Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation" XP_017018057.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176409 "Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins" XP_017019080.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041631420.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017033585.1 30 Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-1170546;Reactome: R-HSA-5684264;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783 "Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Prolactin receptor signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome" XP_017029116.1 7 Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-381070 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"IRE1alpha activates chaperones" XP_041632656.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017019814.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_041631189.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017019857.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017036067.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017032597.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041633164.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017028196.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_017035186.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017022763.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024520.1 6 Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-5685939 "PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)" XP_017018474.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017017022.1 57 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins" XP_041632708.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017023810.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017021713.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017032199.1 5 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017028022.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017029386.1 3 KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3 "Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism" XP_017018412.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017020655.1 4 KEGG: 00510+3.2.1.114;KEGG: 00513+3.2.1.114;MetaCyc: PWY-7920;MetaCyc: PWY-7426 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)" XP_017029846.1 25 Reactome: R-HSA-8877330;Reactome: R-HSA-8939243;Reactome: R-HSA-8878166;Reactome: R-HSA-8936459;Reactome: R-HSA-8939242;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-8939246;Reactome: R-HSA-8941858;Reactome: R-HSA-8951936;Reactome: R-HSA-8941284;Reactome: R-HSA-8939247;Reactome: R-HSA-8941332;Reactome: R-HSA-8949275;Reactome: R-HSA-8939245;Reactome: R-HSA-8941326;Reactome: R-HSA-8931987;Reactome: R-HSA-8939256;Reactome: R-HSA-8941333;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8951911;Reactome: R-HSA-8935964;Reactome: R-HSA-9616222 "RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional regulation by RUNX2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity";"RUNX3 regulates p14-ARF";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates genes involved in cell migration";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates bone development";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates expression of components of tight junctions";"Transcriptional regulation of granulopoiesis" XP_017018669.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_041630764.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017029910.1 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017036200.1 14 MetaCyc: PWY-3661;MetaCyc: PWY-2201;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1 "Glycine betaine degradation I";"Folate transformations I";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Photorespiration ";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Methane metabolism";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)" XP_017036115.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-68952;Reactome: R-HSA-5696397 "Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_017024413.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017027736.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" XP_017027658.2 17 Reactome: R-HSA-6796648;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167152 "TP53 Regulates Transcription of DNA Repair Genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017037655.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_041630907.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017031551.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017033638.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017032802.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017019600.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017025677.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017021301.1 5 KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1;Reactome: R-HSA-199220;MetaCyc: PWY-6012;MetaCyc: PWY-6289 "Pantothenate and CoA biosynthesis";"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein metabolism";"Petrobactin biosynthesis" XP_041631964.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017023537.1 9 Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7385 "Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)" XP_041632133.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017018176.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017038540.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017019170.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017030889.1 5 MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" XP_017036306.2 7 KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;MetaCyc: PWY-5188;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation" XP_017032552.1 8 MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-2301;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;MetaCyc: PWY-6372 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" XP_017037210.1 5 Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36 "Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_017029106.1 4 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism" XP_017025671.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017027309.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171 "Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions" XP_041632883.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017036640.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_041632768.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_041632963.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017020054.1 10 MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171 "1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_041631202.1 4 Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030 "Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis" XP_041631778.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_017034216.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_017029054.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017018722.1 6 KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;MetaCyc: PWY-5723 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt" XP_017023848.1 10 MetaCyc: PWY-3841;MetaCyc: PWY-7199;Reactome: R-HSA-69205;MetaCyc: PWY-7187;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210 "Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_017016326.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017035884.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017033617.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6807505 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes" XP_017031156.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017026610.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_041630925.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017025128.1 10 MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system" XP_017026208.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017032576.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017016483.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017032492.1 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" XP_017029789.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017017035.1 30 Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-917937;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-1170546;Reactome: R-HSA-5684264;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-2644607 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Iron uptake and transport";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"Prolactin receptor signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Interleukin-1 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling" XP_017020606.1 7 Reactome: R-HSA-3000170;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-373753 "Syndecan interactions";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Nephrin family interactions" XP_017025824.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017034101.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_017020050.1 10 MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Methane metabolism" XP_017026193.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017030646.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041632136.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017023590.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017026196.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_017019038.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017035684.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition" XP_017030176.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017026144.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017022695.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024021.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017030006.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_017021452.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017028650.1 14 MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7279;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism" XP_017028353.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017030444.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_017035990.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_041633144.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017036254.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017030922.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017022069.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041631755.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_017016913.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017030443.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_017033619.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6807505 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes" XP_017037906.1 4 Reactome: R-HSA-1614558;MetaCyc: PWY-5350;KEGG: 00920+2.8.1.1;MetaCyc: PWY-7927 "Degradation of cysteine and homocysteine";"Thiosulfate disproportionation IV (rhodanese)";"Sulfur metabolism";"Sulfide oxidation IV (mitochondria)" XP_017018410.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017029864.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017036376.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_041631737.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_017035322.1 14 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation" XP_017018779.2 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_041632492.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437 "Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation" XP_017032036.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_041631313.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017031246.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017022029.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_017025842.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041631499.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_041630797.1 6 KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017021666.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017034321.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_017018665.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017032049.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_017027034.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017037565.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017029717.1 10 KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Recycling pathway of L1";"mTOR signaling pathway";"Thermogenesis";"RSK activation";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_041632093.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017019941.1 8 MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism" XP_017019634.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017025876.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017016821.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_041632441.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017021057.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_017030235.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_017027242.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_017033316.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_017016756.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_017028273.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_017028541.1 5 MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_017036367.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017026831.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_041633004.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_041630917.1 9 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1 "Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection" XP_017023505.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017019650.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017031795.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017028948.1 7 Reactome: R-HSA-983168;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214 "Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins" XP_017031066.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_017032018.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017028295.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017027763.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017026611.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_017018425.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017025393.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017019605.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017025450.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_017036192.1 13 Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416572;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "RHO GTPases Activate ROCKs";"mTOR signaling pathway";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"G alpha (12/13) signalling events";"Sema4D induced cell migration and growth-cone collapse";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017021579.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic" XP_017021127.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017029397.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017029993.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017037406.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017018453.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017027765.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" XP_017024600.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017033829.1 10 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation" XP_017038462.1 5 MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;Reactome: R-HSA-6798695 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Neutrophil degranulation" XP_017028425.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017021911.1 1 KEGG: 00906+1.23.5.1 "Carotenoid biosynthesis" XP_017030554.1 9 MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis" XP_017027386.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_017034911.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017030533.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017028456.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017021580.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy" XP_017034678.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport" XP_017034296.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017016860.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017021568.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017034273.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017028135.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017028817.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_017031261.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017029559.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway" XP_017030500.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_041632164.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017032870.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_017025105.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017023970.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017028275.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_017030194.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017028485.1 12 MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238;MetaCyc: PWY-6527;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077 "Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Glycerolipid metabolism";"Glycogen synthesis" XP_017020757.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228 "Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Degradation of the extracellular matrix" XP_017033852.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017038126.1 8 Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616 "Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017022304.1 4 Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789 "SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs" XP_017036453.1 8 Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221 "Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis" XP_017028146.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017025008.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_017037577.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_017034127.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017025187.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_017021821.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway" XP_017016755.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_017035512.1 6 MetaCyc: PWY-7717;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-7765;MetaCyc: PWY-5651;KEGG: 00380+1.14.13.9 "3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism" XP_017035722.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_041632700.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017028924.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017025797.1 5 Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109 "Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_017026271.2 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_017028276.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" XP_017028310.1 3 KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3 "Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism" XP_017022228.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_017020194.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017017988.1 9 KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017024993.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017037301.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017026561.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_017017385.1 5 KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_017020601.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017021481.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape" XP_017035898.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017032542.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017019295.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017026492.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017034760.1 5 KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5579006 "Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_017026167.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017020325.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017022728.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017032096.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017031963.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017033416.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017036950.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_017025575.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017028257.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017027953.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins" XP_017037005.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017023686.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427359 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression" XP_017024275.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017033506.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017023999.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017020978.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017022031.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_017037256.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017028441.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017026062.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017022861.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism" XP_017018685.1 8 Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1 "Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis" XP_017020995.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017017713.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_017023059.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017037147.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017027365.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017022022.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_017017446.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_017038481.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" XP_017035333.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017033968.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017035727.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017035276.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017030179.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_017025657.1 10 MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13 "Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism" XP_017033591.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_017016907.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017025119.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017030027.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_017024235.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017021232.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017024842.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017018613.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017031013.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041631782.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017018895.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017026726.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017034500.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017018062.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_017023693.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017037296.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017021144.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_041632903.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017020489.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017037898.1 1 Reactome: R-HSA-419771 "Opsins" XP_017033906.1 20 MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136 "Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)" XP_017036310.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017019241.1 17 KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-69601;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;Reactome: R-HSA-75035;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1433557 "Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Relaxin signaling pathway";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Signaling by SCF-KIT" XP_017030494.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_041632462.1 42 Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632 "Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PRC2 methylates histones and DNA";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"DNA methylation";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"Meiotic synapsis" XP_017037110.1 4 Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300 "Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors" XP_017030415.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017032112.1 5 KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171 "Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis" XP_017023947.1 12 MetaCyc: PWY-6613;KEGG: 00670+2.1.2.9;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6277;KEGG: 00970+2.1.2.9;KEGG: 00230+2.1.2.2;Reactome: R-HSA-196780;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate" XP_017023099.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017031104.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017027480.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017022505.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_017024819.1 5 Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling" XP_017022301.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-202733;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253 "Retinoid metabolism and transport";"Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Cell surface interactions at the vascular wall";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_017035737.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017025402.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation" XP_017033573.1 10 KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23 "Glycosaminoglycan degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Other glycan degradation" XP_017028079.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017023105.1 3 Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169 "HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis" XP_017016959.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_041630498.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017025580.1 19 Reactome: R-HSA-8876725;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-3214858;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Protein methylation";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"RMTs methylate histone arginines";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017019322.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_041630454.1 30 Reactome: R-HSA-389513;Reactome: R-HSA-8941332;Reactome: R-HSA-8876198;KEGG: 04714+2.7.11.1;Reactome: R-HSA-111447;Reactome: R-HSA-5218920;Reactome: R-HSA-6804759;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-5628897;Reactome: R-HSA-392451;Reactome: R-HSA-6804758;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-9634638;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-6804757;Reactome: R-HSA-1358803;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-69656;Reactome: R-HSA-9614399;Reactome: R-HSA-211163;Reactome: R-HSA-199418 "CTLA4 inhibitory signaling";"RUNX2 regulates genes involved in cell migration";"RAB GEFs exchange GTP for GDP on RABs";"Thermogenesis";"Activation of BAD and translocation to mitochondria";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Activity through Association with Co-factors";"Relaxin signaling pathway";"Cyclin E associated events during G1/S transition";"TP53 Regulates Metabolic Genes";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Activity through Acetylation";"Human papillomavirus infection";"Regulation of PTEN stability and activity";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"mTOR signaling pathway";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Degradation";"Downregulation of ERBB2:ERBB3 signaling";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of localization of FOXO transcription factors";"AKT-mediated inactivation of FOXO1A";"Negative regulation of the PI3K/AKT network" XP_017026608.1 5 Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16 "Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_041630784.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017033505.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_017030187.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017037169.1 7 MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148 "Choline biosynthesis III";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Synthesis of PG" XP_017022774.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017024409.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017027688.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_017018246.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin" XP_017023901.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-8873719 "Intra-Golgi traffic";"RAB geranylgeranylation" XP_017025218.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"MHC class II antigen presentation";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_017023777.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017026477.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017032093.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_017019646.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017027952.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_041630464.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_041631520.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017016337.1 19 Reactome: R-HSA-70263;Reactome: R-HSA-71403;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37 "Gluconeogenesis";"Citric acid cycle (TCA cycle)";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism" XP_017017034.1 5 MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_017027187.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017024393.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017038472.1 13 Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745 "Retrograde neurotrophin signalling";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"Recycling pathway of L1";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" XP_017017698.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017020583.1 3 Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361 "Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins" XP_041632489.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017036186.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017016781.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017038100.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017016407.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_017032008.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017019796.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017025949.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017028203.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_017017583.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041631315.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017016693.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_017016392.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017037523.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017034111.1 6 MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356 "Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage IV (yeast)" XP_017029359.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017037250.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017022258.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex" XP_017033096.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017024698.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_041630711.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017037457.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017030463.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_017025189.1 6 KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017030578.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017019645.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017021097.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017031678.1 3 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" XP_041630420.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017020910.2 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017023583.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_041631546.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017017753.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51 "Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism" XP_017024531.1 8 Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695 "Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation" XP_017034795.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017035836.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017036812.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_017028008.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024411.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017026195.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017029786.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017032046.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_041630936.1 12 Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;Reactome: R-HSA-451308 "Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor" XP_017026840.1 42 Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-110331;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-606279;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632 "Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"DNA methylation";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"Meiotic synapsis" XP_017028115.1 26 Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025 "Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"MHC class II antigen presentation";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation" XP_017028446.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017027959.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017017951.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017018756.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017027664.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017030717.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041632114.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_041631295.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017018485.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017024626.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017028334.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017038569.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017034758.1 5 KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403 "Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling" XP_017036096.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017028622.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017033589.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017030514.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017021030.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017027189.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_041632130.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017033903.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017024637.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017016978.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017024824.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_017033504.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017022177.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_017025475.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017029502.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-141430 "Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_017029120.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion" XP_017034310.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017029727.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017029986.1 4 Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737 "Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis" XP_017036341.1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764 "Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Degradation of DVL";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling" XP_017037009.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017029511.1 8 MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-6556;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_041630360.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017024812.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition" XP_017038224.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_017037016.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017027826.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017018702.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017018697.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_017036776.1 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017036701.1 10 Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837 "Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation" XP_017021088.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024316.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017036958.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_017038007.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017034153.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_017016538.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017018150.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017028292.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017035932.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_017035459.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017033037.1 5 Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-936964 "TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_017016758.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_017025981.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041632623.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017034931.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017020092.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017029842.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017026002.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017035366.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_017026687.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017020060.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_017033512.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017031597.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_017037133.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017025897.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017025333.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017019846.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017038452.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017022356.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017016362.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017016662.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017027801.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_017025147.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041630271.1 22 Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747 "Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated" XP_017019630.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017019251.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017031085.1 6 Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537 "Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex" XP_017029741.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_017034189.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017030177.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017027138.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017021028.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017025458.1 20 Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397 "Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Polymerase switching";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_017036691.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752 "Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated" XP_017020302.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017022020.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_017033331.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017036006.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017031989.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_041631591.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017034425.1 19 MetaCyc: PWY-561;MetaCyc: PWY-7383;Reactome: R-HSA-71403;KEGG: 00680+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6728 "Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citric acid cycle (TCA cycle)";"Methane metabolism";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle" XP_017019059.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_017035650.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_017025920.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017032736.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041631583.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_041631226.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017036548.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017027232.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017016556.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-6722 "3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"Candicidin biosynthesis" XP_017018696.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017038070.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041632118.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017028375.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017028549.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017028885.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_017030818.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017023931.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017025269.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017037988.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017027472.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017027287.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Degradation of DVL";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_041631650.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_041631992.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017034206.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_017024186.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017025414.1 3 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation" XP_017029169.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017020366.1 3 KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_017027705.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017038401.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_017035434.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_041633439.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_017026752.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017021834.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017036261.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation" XP_017026474.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_017021081.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017018211.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017024564.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017032168.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017029839.1 13 KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902 "Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)" XP_017038308.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017029925.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017019730.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017029989.1 4 MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism" XP_017032039.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017038410.1 9 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476 "Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events" XP_017038318.1 3 Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_017036814.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_041633165.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017032856.1 17 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-1834949;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693565 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Cytosolic sensors of pathogen-associated DNA";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017028864.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017036903.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32 "alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_017018597.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017016338.1 19 KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;Reactome: R-HSA-71403;Reactome: R-HSA-70263;MetaCyc: PWY-561;MetaCyc: PWY-7383;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969 "Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Citric acid cycle (TCA cycle)";"Gluconeogenesis";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_041633273.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017037337.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_017019911.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041631586.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017021816.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017038317.1 9 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection" XP_017019635.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017021161.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017037429.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_017019335.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_041631289.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_017030460.1 40 Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-75953 "mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation" XP_017020065.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017019696.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017017032.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017018579.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017031985.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041632803.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017035210.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017023166.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017034642.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041633420.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017035754.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017026168.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_017033427.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_041631538.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041632245.1 42 Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-5693607;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772 "Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"Meiotic synapsis";"RMTs methylate histone arginines";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"DNA methylation";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape" XP_017030886.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017034453.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_017038243.1 6 Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840 "Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Rho GTPase cycle" XP_017020634.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017030039.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_017033637.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017018245.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025 "Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation" XP_017016935.1 11 KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-5381;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6607;KEGG: 00760+3.1.3.5 "Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism" XP_017035724.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017033949.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017024721.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017026132.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017038060.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_017036094.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017016840.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_017029014.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017037822.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017034067.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017025254.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_017019900.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238 "Neutrophil degranulation";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II" XP_017028290.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_041630729.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017028012.1 24 KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;Reactome: R-HSA-5625740;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Activation of AKT2";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"RHO GTPases activate PKNs";"RSK activation";"Thermogenesis";"FCERI mediated NF-kB activation";"Integrin signaling";"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection" XP_041631963.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017035350.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER" XP_017026286.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017029519.1 7 Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-9020265;Reactome: R-HSA-9018896;Reactome: R-HSA-9023661;Reactome: R-HSA-6798695;Reactome: R-HSA-9018676 "Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Neutrophil degranulation";"Biosynthesis of D-series resolvins" XP_017035716.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017031738.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017025326.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017033896.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017035133.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017024635.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_041632734.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_017037700.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021188.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017018076.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017023625.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-936837 "Cation-coupled Chloride cotransporters";"Ion transport by P-type ATPases" XP_041631539.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017034094.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017034463.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes" XP_017032803.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017035478.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017033435.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017027261.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017022109.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017025459.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017034526.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017035912.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_017027252.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs" XP_017020894.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017034761.1 5 Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_017029928.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695 "Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism";"Neutrophil degranulation" XP_017020962.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017032051.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017021482.1 7 KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121 "Purine metabolism";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I" XP_017019719.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017026658.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_017035158.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017022435.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_017027275.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017038629.1 11 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-3214847 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones" XP_017024749.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041632724.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017029147.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism" XP_017037141.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017016540.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017024383.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017037048.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis" XP_017033811.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017021870.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041632765.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017017037.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_017021399.1 5 MetaCyc: PWY-6168;MetaCyc: PWY-5523;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863 "Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Roseoflavin biosynthesis" XP_017023330.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_017036287.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Gap junction degradation";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_041630554.1 12 KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728 "Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle" XP_041633070.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017034677.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017017484.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_017031740.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017020892.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017017487.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_017033845.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017019755.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_041631076.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017037479.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017018599.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017031863.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_017020744.1 6 Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759 "Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors" XP_017024530.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017031593.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017038322.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7117 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_017020441.1 3 KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801 "Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)" XP_017017529.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017020401.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_017023886.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017027604.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017025851.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017030700.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_017037533.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017017528.1 11 Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-174430 "Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Telomere C-strand synthesis initiation" XP_017022707.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041633175.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017023100.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017024167.2 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017035376.1 9 KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-6842 "Drug metabolism - other enzymes";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Glutathione-mediated detoxification II" XP_017028327.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_041632342.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017037422.1 9 Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-165159;Reactome: R-HSA-9639288 "Regulation of PTEN gene transcription";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"mTOR signalling";"Amino acids regulate mTORC1" XP_017036194.1 13 Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017037537.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017019928.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" XP_017024918.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017023902.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6811438 "RAB geranylgeranylation";"Intra-Golgi traffic" XP_017031478.1 1 Reactome: R-HSA-419771 "Opsins" XP_041631518.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Activation of RAC1" XP_041631638.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017031431.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_017018060.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_017030033.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017017673.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041630609.1 44 Reactome: R-HSA-5654732;KEGG: 04150+2.7.11.24;Reactome: R-HSA-3371453;Reactome: R-HSA-198753;Reactome: R-HSA-2871796;Reactome: R-HSA-162658;Reactome: R-HSA-202670;Reactome: R-HSA-74749;Reactome: R-HSA-444257;Reactome: R-HSA-5663213;Reactome: R-HSA-9627069;Reactome: R-HSA-5654733;Reactome: R-HSA-5654726;Reactome: R-HSA-5673001;Reactome: R-HSA-8939211;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-5654727;Reactome: R-HSA-2029482;Reactome: R-HSA-5674135;Reactome: R-HSA-112409;Reactome: R-HSA-6802946;Reactome: R-HSA-5674499;Reactome: R-HSA-445144;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-6811558;Reactome: R-HSA-1295596;Reactome: R-HSA-879415;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-2559582;Reactome: R-HSA-5668599;Reactome: R-HSA-8940973;Reactome: R-HSA-6802952;Reactome: R-HSA-881907;Reactome: R-HSA-2559585;Reactome: R-HSA-8943724;Reactome: R-HSA-456926;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-375165;Reactome: R-HSA-982772;Reactome: R-HSA-170968 "Negative regulation of FGFR3 signaling";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"ERK/MAPK targets";"FCERI mediated MAPK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"ERKs are inactivated";"Signal attenuation";"RSK activation";"RHO GTPases Activate WASPs and WAVEs";"Regulation of the apoptosome activity";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR1 signaling";"RAF/MAP kinase cascade";"ESR-mediated signaling";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of FGFR2 signaling";"Regulation of actin dynamics for phagocytic cup formation";"MAP2K and MAPK activation";"RAF-independent MAPK1/3 activation";"Signaling by moderate kinase activity BRAF mutants";"Negative feedback regulation of MAPK pathway";"Signal transduction by L1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Spry regulation of FGF signaling";"Advanced glycosylation endproduct receptor signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"Senescence-Associated Secretory Phenotype (SASP)";"RHO GTPases Activate NADPH Oxidases";"RUNX2 regulates osteoblast differentiation";"Signaling by BRAF and RAF fusions";"Gastrin-CREB signalling pathway via PKC and MAPK";"Oncogene Induced Senescence";"Regulation of PTEN gene transcription";"Thrombin signalling through proteinase activated receptors (PARs)";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"NCAM signaling for neurite out-growth";"Growth hormone receptor signaling";"Frs2-mediated activation" XP_017038237.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017026207.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_017030812.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921 "EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation" XP_041633149.1 7 KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Arginine biosynthesis" XP_017018468.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017023856.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_041632691.1 42 Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-110331 "PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"DNA methylation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"RMTs methylate histone arginines";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged purine" XP_041631111.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_041633042.1 30 Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-1170546;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5676590 "Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Prolactin receptor signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Degradation of GLI1 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling" XP_017029115.1 7 Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381183 "PERK regulates gene expression";"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes" XP_017031674.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017017666.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_017034104.1 4 KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism" XP_017029668.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017026489.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017024028.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017031116.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017028731.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017019068.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_017029257.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_017026222.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_041632487.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017034955.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017019461.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017032231.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040 "G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_017038229.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041632649.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_041631790.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017025633.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion" XP_041630756.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017035439.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017027683.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017031545.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017019924.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017028317.1 4 MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14 "Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism" XP_017029758.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_041632181.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017034394.1 6 MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6608 "Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III" XP_017017386.1 5 MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism" XP_017021382.2 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_017037529.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017028271.1 5 Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_017018090.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_041633139.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events" XP_041632610.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017036253.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_041630851.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017024446.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017022891.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017034889.1 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_017028827.1 5 MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_017036716.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_017026494.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017027416.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation" XP_041632707.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017025325.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017016991.1 24 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-8852276 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_017019264.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017035638.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_041631144.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017038135.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_017026140.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017019908.1 20 KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;Reactome: R-HSA-1268020;MetaCyc: PWY-7384;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Mitochondrial protein import";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Propanoate metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)" XP_017020214.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017033887.1 5 MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_017019661.1 42 Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-5334118;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-5250924 "HCMV Early Events";"PRC2 methylates histones and DNA";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"DNA methylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"Meiotic synapsis";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression" XP_017024243.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017031477.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017020461.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017035733.1 14 Reactome: R-HSA-8931987;MetaCyc: PWY-5667;MetaCyc: PWY-8055;Reactome: R-HSA-2426168;MetaCyc: PWY-8053;Reactome: R-HSA-75109;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7411;Reactome: R-HSA-9018519;KEGG: 00564+2.3.1.15 "RUNX1 regulates estrogen receptor mediated transcription";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Estrogen-dependent gene expression";"Glycerophospholipid metabolism" XP_017028829.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017037628.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017030531.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017022266.1 57 Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-350562 "Degradation of DVL";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)" XP_017024629.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017018923.2 6 Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017036444.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244 "Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation" XP_017038115.1 10 KEGG: 00051+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70263 "Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism";"Glycerol degradation to butanol";"Gluconeogenesis" XP_017016612.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017022582.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017019725.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017020061.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_017020258.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017020012.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_017025403.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017036193.1 13 Reactome: R-HSA-416482;Reactome: R-HSA-416572;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "G alpha (12/13) signalling events";"Sema4D induced cell migration and growth-cone collapse";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"RHO GTPases Activate ROCKs";"EPHB-mediated forward signaling";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017021967.1 29 Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-72086 "Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"mRNA Capping" XP_017026026.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017038630.1 11 Reactome: R-HSA-167162;Reactome: R-HSA-5689880;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161 "RNA Polymerase II HIV Promoter Escape";"Ub-specific processing proteases";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation" XP_041631176.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017024843.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017037535.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017019548.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_041631766.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017033407.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017024751.1 10 KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10 "Butanoate metabolism";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies" XP_017023596.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017038408.1 9 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-416476 "Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events" XP_017038570.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017036498.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017037068.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_041632509.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017032503.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017017819.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017036896.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017037953.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_017022987.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017026523.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017035677.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017035655.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017029945.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_017029669.2 4 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism" XP_017033503.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_041631045.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017028377.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_041631862.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017020486.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_041633499.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017028734.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_041631034.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_017026086.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017037561.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017037297.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017023383.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622 "Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)" XP_041631432.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_017018375.1 3 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_017035292.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017018115.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359 "Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation" XP_017026886.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_017026690.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex" XP_017025038.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_041630740.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017037237.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017036384.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_017032114.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017023963.1 5 MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" XP_017017387.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_017027903.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017027919.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_041631484.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017034684.1 18 Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_017027837.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017022744.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_041633076.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017022360.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017024263.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017036866.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017034646.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017033901.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017035995.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_017025116.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_017025540.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017036364.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017026283.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_017016914.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017026524.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017018401.1 29 Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-73779 "RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017035812.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017027421.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041633485.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017033183.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_017024333.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017034505.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017028732.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017024859.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017031223.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_017027150.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_017034412.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-191859 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"snRNP Assembly" XP_041633024.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017017078.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017022279.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017024609.1 8 MetaCyc: PWY-7400;MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5;Reactome: R-HSA-70635;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4983 "L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Canavanine biosynthesis";"Urea cycle";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)" XP_017017620.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017030694.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017020064.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035 "RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_017027291.1 14 Reactome: R-HSA-75109;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;Reactome: R-HSA-1483213 "Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE" XP_017030278.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_017019293.1 6 MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;Reactome: R-HSA-1474151 "Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_041632129.1 42 Reactome: R-HSA-5693571;Reactome: R-HSA-110328;Reactome: R-HSA-3214841;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472 "Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PKMTs methylate histone lysines";"RMTs methylate histone arginines";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"Processing of DNA double-strand break ends";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017023566.1 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_017032891.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017018906.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017033473.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-983231 "PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production" XP_017033507.1 13 Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-450302;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-937042 "Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"activated TAK1 mediates p38 MAPK activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex" XP_017020770.1 3 MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway" XP_017032200.1 5 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017029044.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017031850.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_017022572.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-6453 "Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis" XP_017031680.1 5 KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32 "Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism" XP_041631299.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-381676 "Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_017019764.1 52 Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-5250924;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Transcriptional regulation by small RNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination" XP_017022334.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_017021775.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017019609.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_041631849.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017036897.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017023078.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606 "Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_041633282.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017017618.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017038563.1 10 MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901 "Glycerol degradation to butanol";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation" XP_017034281.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017024633.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017019043.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017036713.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_017027838.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017020232.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017022765.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017029919.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017022298.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253 "Retinoid metabolism and transport";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_017037402.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017033461.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017022032.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_017023531.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017022829.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017025756.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_041632440.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017030277.1 5 Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-1169408 "RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"ISG15 antiviral mechanism" XP_017035820.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017023220.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_017028155.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017030551.1 9 Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_017026767.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017023632.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation" XP_041633406.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017020761.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017028663.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_017028560.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_041631618.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_017031793.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017025963.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017025030.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017017502.1 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_017029983.1 4 KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737 "Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis" XP_017035760.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017026136.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-180534 "Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"Downstream TCR signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4" XP_017026204.1 3 KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45 "Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_017030442.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017035511.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs" XP_017037790.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_017020992.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017028800.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017034190.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017035636.1 9 Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-68962 "Telomere C-strand synthesis initiation";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex" XP_017021472.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017032067.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017030193.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_041632754.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017019943.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_017033571.1 10 KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695 "Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"MPS VII - Sly syndrome";"Other glycan degradation";"HS-GAG degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Neutrophil degranulation" XP_017037023.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_017035371.1 11 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events";"mTOR signaling pathway" XP_017016406.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017024236.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017025091.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017020276.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017021505.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_017036098.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_017023493.1 14 Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167238 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_017031705.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_041631031.1 14 MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51 "Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism" XP_017026209.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017030705.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation" XP_017024276.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017035396.1 18 KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051 "Linoleic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis I" XP_041631113.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017035723.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017032541.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017022930.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation" XP_017037987.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017023000.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_017034160.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017032844.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_017021168.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017037471.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_041630758.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017030607.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017021187.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017020278.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017022402.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017032500.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017027144.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_041632010.1 12 KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972 "Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017029103.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017034276.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017029969.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017016807.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017034620.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017020789.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017035948.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017030430.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017035352.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_041631044.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017030698.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_017026723.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_017025844.1 58 KEGG: 00592+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00310+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-5138;Reactome: R-HSA-77305;MetaCyc: PWY-7726;KEGG: 00380+4.2.1.17;Reactome: R-HSA-77285;MetaCyc: PWY-7779;Reactome: R-HSA-1482798;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-5177;MetaCyc: PWY-6945;MetaCyc: PWY-5136;MetaCyc: PWY-6944;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17;KEGG: 00362+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;Reactome: R-HSA-77348;KEGG: 00280+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7007;KEGG: 00281+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00410+4.2.1.17;Reactome: R-HSA-77350;MetaCyc: PWY-6583;KEGG: 00650+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-6946;Reactome: R-HSA-77346;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-7778;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00930+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-5789;KEGG: 00071+4.2.1.17+1.1.1.211 "alpha-Linolenic acid metabolism";"Fatty acid elongation";"Lysine degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Tryptophan metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Methyl tert-butyl ether degradation";"Acyl chain remodeling of CL";"Phenylalanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Benzoate degradation";"Toluene degradation";"Lysine degradation";"Fatty acid salvage";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Valine, leucine and isoleucine degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Geraniol degradation";"Propanoate metabolism";"beta-Alanine metabolism";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Pyruvate fermentation to butanol I";"Butanoate metabolism";"Fermentation to 2-methylbutanoate";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid elongation";"Tryptophan metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Aminobenzoate degradation";"Limonene and pinene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"Butanoate metabolism";"Caprolactam degradation";"Pyruvate fermentation to hexanol (engineered)";"Caprolactam degradation";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid degradation" XP_017030863.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017019324.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017037787.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_017037168.1 7 KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166 "Ether lipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA" XP_017026292.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" XP_017038157.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017030034.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017028201.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_017033184.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041632121.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017034186.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017016463.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017018439.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_041630727.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017016652.1 7 KEGG: 00071+1.3.8.7;Reactome: R-HSA-1989781;Reactome: R-HSA-77348;Reactome: R-HSA-77346;KEGG: 00280+1.3.8.7;Reactome: R-HSA-77288;MetaCyc: PWY-7094 "Fatty acid degradation";"PPARA activates gene expression";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Valine, leucine and isoleucine degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid salvage" XP_017027205.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017036600.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017018870.1 8 Reactome: R-HSA-5659996;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;Reactome: R-HSA-71336;Reactome: R-HSA-6791461;MetaCyc: PWY-1861;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723 "RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Rubisco shunt" XP_017027666.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017026458.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099 "Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling" XP_017022694.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017018566.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017034306.1 4 KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism" XP_041632207.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017019321.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017027519.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017033698.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_017023855.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017032839.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206302;Reactome: R-HSA-2024101 "HS-GAG degradation";"MPS I - Hurler syndrome";"CS/DS degradation" XP_017019643.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_041633065.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017023085.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017017523.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_017034995.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017018008.1 11 MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;MetaCyc: PWY-7791;MetaCyc: PWY-5154;KEGG: 00240+2.1.3.2 "UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism" XP_017022858.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017034950.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_017016611.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_017020234.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017016669.1 7 KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-6134 "Folate biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"L-tyrosine biosynthesis IV" XP_017023593.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017033315.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_017030546.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_017022988.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017026562.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017036783.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017022499.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_041631660.1 6 MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900 "Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_017016847.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_017037212.1 5 KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499 "Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane" XP_017029061.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041631975.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017022745.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_017036252.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-171007 "mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"p38MAPK events" XP_017025895.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017024072.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017031540.1 19 Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-432142 "Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Chylomicron clearance";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"LDL clearance";"LDL remodeling";"Chylomicron assembly";"VLDL assembly";"VLDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Platelet sensitization by LDL" XP_041631733.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017028307.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017035339.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017038461.1 5 Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_017035649.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_017027172.1 5 MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_017017079.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_041632461.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017025567.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017033090.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_017036222.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017036572.1 6 Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-381426;Reactome: R-HSA-381033 "CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones" XP_041632625.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017020055.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017023662.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017021769.1 4 Reactome: R-HSA-3359462;Reactome: R-HSA-196741;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011 "Defective AMN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance" XP_017022262.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017019895.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_017024905.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017027374.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017035730.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017035237.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017022351.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017033415.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017031041.1 13 MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6728 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle" XP_017032124.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_017037786.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_017033584.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017021406.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_041632736.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017035565.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017027009.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017031174.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017025219.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017023580.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones" XP_017026628.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017026614.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017016325.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017024026.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017023752.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_017038464.1 4 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation" XP_017026753.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_041632406.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558 "Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_017029859.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_017030588.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_017023683.1 5 Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946 "Signaling downstream of RAS mutants";"RAF activation";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants" XP_017035068.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017019085.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-111932 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF activation";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB" XP_017037095.1 6 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism" XP_017021976.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725 "Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_017036861.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_017029198.1 3 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import" XP_017036447.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;MetaCyc: PWY-7221 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis" XP_017036654.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_017032956.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017036827.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017033399.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_017027812.1 56 Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-5610785;Reactome: R-HSA-75815 "APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D" XP_017023157.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017035736.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017036223.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017036686.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017023946.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017026063.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017020703.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017035063.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720 "Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"DARPP-32 events";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_017031218.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_017025585.1 6 Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;MetaCyc: PWY-6906;MetaCyc: PWY-7395 "Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation" XP_017020082.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017034872.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017022735.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017034247.1 5 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_017020097.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017035719.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017034458.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-8875656 "Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"MET receptor recycling" XP_017021108.1 5 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20 "Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes" XP_017027227.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017017690.1 4 KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270 "Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate" XP_041633494.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017035293.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017020096.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017016465.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017023997.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017029994.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017028274.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" XP_017038451.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017022709.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017020555.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017024833.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017026203.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_041632702.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017034411.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_017036684.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017034151.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017032847.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_017031511.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_041632612.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017036700.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017018671.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017035817.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017024019.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017035897.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017038329.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_017018491.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017029930.1 4 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782861 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)" XP_017030339.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017020549.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862 "Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017036603.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017030091.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_041630585.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-9616222;Reactome: R-HSA-73728;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-5250924;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-69473;Reactome: R-HSA-1912408 "Meiotic recombination";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Opening";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"B-WICH complex positively regulates rRNA expression";"HCMV Early Events";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"Meiotic synapsis";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"G2/M DNA damage checkpoint";"Pre-NOTCH Transcription and Translation" XP_017032079.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017033665.1 7 Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11 "Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms" XP_017021086.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041631544.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017038307.1 16 KEGG: 00640+6.2.1.4;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5 "Propanoate metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Itaconate degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)" XP_017038029.1 7 KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25 "Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism" XP_017023592.1 4 Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75 "tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis" XP_017035707.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017028520.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017031550.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017016660.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017021072.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_017029324.1 9 KEGG: 00010+1.2.1.12;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-8004 "Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis";"Entner-Doudoroff pathway I" XP_017038588.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017027033.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017022507.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174048 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_017034178.1 8 Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580 "PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence" XP_017031219.1 14 Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-6782135 "Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER" XP_017036860.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_017022612.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017019299.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796;Reactome: R-HSA-381426 "Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_017031659.1 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017037789.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_017026649.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_041630755.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017038585.1 8 Reactome: R-HSA-6787639;MetaCyc: PWY-5740;MetaCyc: PWY-5738;MetaCyc: PWY-5739;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573 "GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis" XP_017030498.1 8 Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724 "mTOR signalling";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription" XP_041632950.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017037528.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017036395.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017017342.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017024264.1 8 Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757 "Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Ub-specific processing proteases";"Regulation of TP53 Degradation" XP_017031280.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017027149.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_017025240.1 7 Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-69205 "CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription" XP_017037788.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017038238.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041631080.1 30 Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-917937 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport" XP_017033245.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017028967.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017034115.2 14 MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-975634 "Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Retinoid metabolism and transport" XP_017036906.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_017025619.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017034893.1 5 Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68 "Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis" XP_017027672.1 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_017035720.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017030718.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017023633.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017018097.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"