Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_016971107.1	12	Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4	"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Selenate reduction";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Purine metabolism"
XP_044317112.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_016982951.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_016991059.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016973235.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016974955.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_016978588.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016988563.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158	"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_016978906.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016983525.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-68877	"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Mitotic Prometaphase"
XP_016978623.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656	"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"MET receptor recycling"
XP_016982209.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_016989331.1	3	Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709	"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins"
XP_016987849.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_016984677.1	13	Reactome: R-HSA-3928663;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482	"EPHA-mediated growth cone collapse";"Relaxin signaling pathway";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events"
XP_016987848.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_016973953.2	9	KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18	"Drug metabolism - other enzymes";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450"
XP_016973121.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016985159.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016982088.2	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_016987315.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044312762.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016991087.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016989419.2	5	MetaCyc: PWY-6012;MetaCyc: PWY-6289;MetaCyc: PWY-6012-1;Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7	"Acyl carrier protein metabolism";"Petrobactin biosynthesis";"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis"
XP_044316775.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_016986797.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_016977986.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_016986705.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044315070.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016976850.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016973585.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016974741.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016987913.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016989067.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_016987542.1	3	KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_016985824.2	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016973352.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016974180.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016987776.1	11	KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-7124;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_016984716.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016983202.2	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_016972899.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_016976538.1	23	Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (i) signalling events"
XP_016978848.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9	"Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism"
XP_044317786.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016979136.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_044316443.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_016978637.2	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016982203.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016986728.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_044314607.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_044316540.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_016990525.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016971658.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016985494.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016988394.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_016981582.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-9603505	"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"NTRK3 as a dependence receptor"
XP_016991091.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_044317328.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_016989586.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016987015.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016986686.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044313408.1	24	KEGG: 05165+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-5625740;KEGG: 04714+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-444257;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"RHO GTPases activate PKNs";"Thermogenesis";"CD28 dependent PI3K/Akt signaling";"RSK activation";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016989326.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016980428.2	5	Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Chromatin modifying enzymes";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044317262.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_044315425.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016989420.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_016986423.1	27	Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5610785;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5358749;Reactome: R-HSA-75815;Reactome: R-HSA-198323;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;KEGG: 04151+2.7.11.1;Reactome: R-HSA-196299;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-399956;Reactome: R-HSA-195253;Reactome: R-HSA-5674400;Reactome: R-HSA-5250924	"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of RUNX2 expression and activity";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"GLI3 is processed to GLI3R by the proteasome";"Thermogenesis";"Degradation of GLI2 by the proteasome";"S37 mutants of beta-catenin aren't phosphorylated";"Ubiquitin-dependent degradation of Cyclin D";"AKT phosphorylates targets in the cytosol";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"PI3K-Akt signaling pathway";"Beta-catenin phosphorylation cascade";"Relaxin signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"APC truncation mutants have impaired AXIN binding";"CRMPs in Sema3A signaling";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by AKT1 E17K in Cancer";"B-WICH complex positively regulates rRNA expression"
XP_016984358.1	3	Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144	"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_016984755.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044314122.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_016981776.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016981598.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016976675.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016977080.1	11	Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-1268020;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111463	"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Mitochondrial protein import";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs"
XP_016980808.1	22	MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7728;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7053;MetaCyc: PWY-7724;MetaCyc: PWY-7592	"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)"
XP_016987113.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044313681.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_016984715.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation"
XP_016980226.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016976059.1	5	MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41	"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system"
XP_044315661.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016975538.2	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_016989911.1	8	Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_016972854.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016982290.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016970047.1	11	Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2979096	"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_016984826.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016975303.2	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_016975364.2	5	KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism"
XP_044315892.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016971033.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016977587.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044316968.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016990973.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982247.2	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_016986911.2	12	Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736	"Synaptic adhesion-like molecules";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors"
XP_016984683.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016980577.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016983804.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016989892.2	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016985027.2	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016977838.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016984157.2	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_016980413.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-75815	"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D"
XP_016979286.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016984439.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016974888.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_044312616.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016981973.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016976622.2	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_044317180.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016977108.2	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_016981042.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016969059.2	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016981888.1	6	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-201722	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044315006.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_016976607.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016973459.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_044315827.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044317132.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016990113.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016983511.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_016973073.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016970533.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_016973469.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044317323.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_016983707.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016969984.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016982796.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_044317274.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_044316806.1	5	MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_016988742.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_016983522.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_016973643.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
XP_044313834.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016974726.2	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_044313622.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_016979624.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_016977857.2	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_016988894.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016985361.1	18	MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis"
XP_016990504.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016986424.1	27	Reactome: R-HSA-5358752;Reactome: R-HSA-8939902;Reactome: R-HSA-4641262;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-75815;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5358749;Reactome: R-HSA-5610785;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;KEGG: 04926+2.7.11.1;Reactome: R-HSA-196299;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5467340;Reactome: R-HSA-5250924;Reactome: R-HSA-5674400;Reactome: R-HSA-195253;Reactome: R-HSA-399956;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5467337;KEGG: 05165+2.7.11.1	"T41 mutants of beta-catenin aren't phosphorylated";"Regulation of RUNX2 expression and activity";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human cytomegalovirus infection";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Degradation of GLI2 by the proteasome";"S37 mutants of beta-catenin aren't phosphorylated";"GLI3 is processed to GLI3R by the proteasome";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Relaxin signaling pathway";"Beta-catenin phosphorylation cascade";"PI3K-Akt signaling pathway";"AXIN missense mutants destabilize the destruction complex";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by AKT1 E17K in Cancer";"Degradation of beta-catenin by the destruction complex";"CRMPs in Sema3A signaling";"Human immunodeficiency virus 1 infection";"APC truncation mutants have impaired AXIN binding";"Human papillomavirus infection"
XP_016980726.2	11	Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
XP_016968988.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016977553.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016989114.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016986923.2	12	Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001	"Synaptic adhesion-like molecules";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade"
XP_016984041.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_016974767.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016991011.2	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_016984246.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016985892.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism"
XP_016982996.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982135.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016990651.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016983476.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016969530.2	7	Reactome: R-HSA-606279;Reactome: R-HSA-5696394;Reactome: R-HSA-201722;Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER";"Formation of the beta-catenin:TCF transactivating complex";"UCH proteinases";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"HATs acetylate histones"
XP_016985446.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016987222.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events"
XP_044317357.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"PKA activation";"G alpha (z) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway"
XP_016978515.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_044314626.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_016979290.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_044315053.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016975483.1	40	Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167200	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"mRNA Capping";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_016977079.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016979888.2	5	KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II"
XP_016986924.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_016980703.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016971142.1	8	Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750	"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"HCMV Early Events";"Regulation of PTEN gene transcription";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6"
XP_044314861.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016980685.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016980617.2	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_044314590.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016985284.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-1799339	"Neutrophil degranulation";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane"
XP_016991997.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016975539.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016986084.1	15	MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;Reactome: R-HSA-70171	"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Purine metabolism";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis"
XP_016986714.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016984383.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979788.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_044314457.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_016970172.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394	"Neddylation";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER"
XP_016972589.1	7	KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;MetaCyc: PWY-6605;MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-7805;Reactome: R-HSA-6798695	"Purine metabolism";"Glyphosate degradation III";"Adenine and adenosine salvage II";"Adenine salvage";"Purine salvage";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation"
XP_044312414.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016976624.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016982583.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016977661.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016989025.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016982712.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_044312907.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016973665.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016979862.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016990719.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016984216.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016982742.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation"
XP_016978319.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044314841.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II"
XP_044314026.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_016991922.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_044314343.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-2151209	"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_016981455.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044316388.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_016981890.1	10	MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-1722	"L-histidine degradation III";"One carbon pool by folate";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate"
XP_016973417.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_016980224.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_016984233.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044315996.1	5	MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis"
XP_016991273.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;KEGG: 00710+2.7.2.3	"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms"
XP_016977318.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016970569.2	5	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_016985798.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-8873719	"Intra-Golgi traffic";"RAB geranylgeranylation"
XP_016971239.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016975257.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016973601.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016991027.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016981141.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425	"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Downstream TCR signaling";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_016982865.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_016978947.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044317673.1	14	MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-4419969	"Stigma estolide biosynthesis";"Ether lipid metabolism";"Synthesis of PC";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Synthesis of PE";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina"
XP_016976561.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044313122.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016987983.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016977812.2	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_016991526.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016986549.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_016973176.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016991246.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_016990254.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016976750.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_016983641.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016985651.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-373080	"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO";"Class B/2 (Secretin family receptors)"
XP_016985476.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016988190.1	16	Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-1234176;Reactome: R-HSA-167238;Reactome: R-HSA-167246	"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_016978664.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016988245.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016973007.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016983672.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_016980558.1	4	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis"
XP_044312410.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016988477.1	13	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"G alpha (q) signalling events";"Human papillomavirus infection";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"NRAGE signals death through JNK";"mTOR signaling pathway";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"MAPK6/MAPK4 signaling";"Human cytomegalovirus infection"
XP_044314022.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016985626.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-1855204	"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_016987298.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"Macroautophagy";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
XP_016973028.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_044314421.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016971873.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_016982418.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_016990490.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016970024.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_016983637.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016978361.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016969415.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_016986863.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016982488.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016980029.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-350562	"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)"
XP_016969953.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044312810.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016986055.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016972615.2	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_044314530.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_016975883.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;Reactome: R-HSA-1855183	"Streptomycin biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_016972734.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_016974831.1	5	Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221	"Signaling downstream of RAS mutants";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway"
XP_016979857.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_016990773.1	20	MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7858	"Jasmonic acid biosynthesis";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II"
XP_016990354.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_044315949.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044315100.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751	"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated"
XP_016980228.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952	"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions"
XP_016979162.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044317067.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016989023.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016969640.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_016986526.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"G1/S-Specific Transcription";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_016971269.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_016971270.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_016975617.2	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_016989632.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-177929	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR"
XP_016975651.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016976673.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016976554.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2	"Oxidative phosphorylation";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis"
XP_044317380.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_044317909.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016987243.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084	"Downstream TCR signaling";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Neddylation";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_044314118.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_016986382.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_016990565.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_044314027.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016983957.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_016990026.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016968867.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592	"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1"
XP_044313808.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;KEGG: 00020+4.2.1.2;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-7254	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)"
XP_044317525.1	14	KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803	"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_016975606.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_016986985.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016974899.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_016979927.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016970892.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016990623.2	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-6811558	"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_044314845.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016986393.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016984988.2	14	Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944	"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2"
XP_016979159.1	57	Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75815	"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D"
XP_016979383.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044316155.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_016991383.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_016968854.2	6	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_044314488.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016984899.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016987773.1	11	KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-5913;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_044316519.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_044314359.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016979345.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016972627.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016986735.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016991337.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016981698.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_044312486.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016977385.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044314096.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801	"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD"
XP_016980321.2	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_016987117.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044317553.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016985130.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_016976537.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016989310.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_016986921.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016988098.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016979821.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_016973096.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_044313075.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016989214.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_016973599.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016985639.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044316577.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_044317555.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044314337.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016977047.2	17	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-6620;MetaCyc: PWY-6627;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation"
XP_016973701.1	10	MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11	"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Glycolysis";"Pentose phosphate pathway";"Methane metabolism";"Fructose and mannose metabolism"
XP_044314020.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044317330.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_016984976.2	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016979033.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_044315109.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016974239.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016990150.2	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_044314357.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044314382.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016986915.2	12	Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932	"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Synaptic adhesion-like molecules"
XP_044317135.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_016988277.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016976570.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044315018.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044314763.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_044314415.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016980364.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016982973.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016972887.1	2	Reactome: R-HSA-9614657;Reactome: R-HSA-5205685	"FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy"
XP_016973093.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016990884.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295	"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"MHC class II antigen presentation"
XP_016969323.2	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_016985738.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes"
XP_016988189.1	16	Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-983168;Reactome: R-HSA-167287	"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery"
XP_016981239.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_016986316.2	11	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_016990180.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016969627.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_016975117.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016980196.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-877300	"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling"
XP_016972131.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016977254.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_016986707.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044315390.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016979468.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044313407.1	24	Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-5625740;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"PI3K-Akt signaling pathway";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Relaxin signaling pathway";"VEGFR2 mediated cell proliferation";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs";"GPVI-mediated activation cascade";"Thermogenesis";"RSK activation";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_016984468.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044314698.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_016980826.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044314031.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_044317256.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_044314888.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_044312722.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016990514.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_044316234.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016990205.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016976601.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016974618.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016991977.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016977478.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II"
XP_044315837.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016972023.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_044315857.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016990556.2	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_044317346.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016985901.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016969667.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016982809.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016986567.1	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688	"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism"
XP_044317801.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_016977491.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_016985341.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257	"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN"
XP_016984786.1	26	Reactome: R-HSA-1362277;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-6804114;Reactome: R-HSA-4615885;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-69205;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-6782135	"Transcription of E2F targets under negative control by DREAM complex";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SUMOylation of DNA replication proteins";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"G1/S-Specific Transcription";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by REV1";"Polymerase switching";"Dual incision in TC-NER"
XP_016987416.2	8	Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962	"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex"
XP_016991572.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016989979.2	13	MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030	"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Folate transformations I";"Folate polyglutamylation";"One carbon pool by folate";"L-histidine degradation III"
XP_044316948.1	6	Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66	"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism"
XP_044314771.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016982357.1	30	Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-400253;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-2644606;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-1170546	"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Circadian Clock";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Prolactin receptor signaling"
XP_016988269.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016979861.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016979056.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_016986816.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_016977664.1	7	Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs"
XP_016969564.2	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_016981889.1	10	KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-1722	"One carbon pool by folate";"L-histidine degradation III";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate"
XP_016983983.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016970022.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016971946.2	3	KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis"
XP_016970545.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016978039.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016971368.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation"
XP_016976516.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016991257.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_016982202.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044317253.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016986373.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016973702.1	10	MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis";"Fructose and mannose metabolism"
XP_016973764.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016985380.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016985640.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_016975130.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044314044.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044316896.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044315579.1	5	MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_016973638.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231	"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production"
XP_044316794.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044313098.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211945	"Xenobiotics";"Endogenous sterols";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds"
XP_016983127.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_016992278.2	19	KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37	"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
XP_016984345.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_044313548.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000178	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"ECM proteoglycans"
XP_016984658.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044312721.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044314257.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016977882.1	5	KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_044317216.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044317800.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_016988412.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_044317322.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_016979805.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016983086.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016983944.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016986871.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044312516.1	4	Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_016982664.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016973124.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016984436.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016981990.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044315855.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016982496.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_016985305.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044315512.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_044313173.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_016986156.1	26	Reactome: R-HSA-174437;Reactome: R-HSA-1362277;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-4615885;Reactome: R-HSA-5685942;Reactome: R-HSA-6804114;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-69205;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-69183;Reactome: R-HSA-8866654;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-110312	"Removal of the Flap Intermediate from the C-strand";"Transcription of E2F targets under negative control by DREAM complex";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"SUMOylation of DNA replication proteins";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G1/S-Specific Transcription";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Processive synthesis on the lagging strand";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by REV1"
XP_016972094.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016979185.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_016982251.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-210744	"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Attenuation phase";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_016986420.1	27	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-399956;Reactome: R-HSA-195253;Reactome: R-HSA-5674400;Reactome: R-HSA-5250924;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5610785;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5358749;Reactome: R-HSA-198323;Reactome: R-HSA-75815;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-4641262;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358752	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"APC truncation mutants have impaired AXIN binding";"CRMPs in Sema3A signaling";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by AKT1 E17K in Cancer";"B-WICH complex positively regulates rRNA expression";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"GLI3 is processed to GLI3R by the proteasome";"Thermogenesis";"Degradation of GLI2 by the proteasome";"S37 mutants of beta-catenin aren't phosphorylated";"AKT phosphorylates targets in the cytosol";"Ubiquitin-dependent degradation of Cyclin D";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Regulation of RUNX2 expression and activity";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human cytomegalovirus infection";"T41 mutants of beta-catenin aren't phosphorylated"
XP_016985302.1	6	KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA"
XP_044315829.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016987119.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016974495.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_044315441.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016971271.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_016970315.1	14	Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862	"Polymerase switching";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK"
XP_016973123.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016983958.2	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_016979835.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044314317.1	7	Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-5685939	"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)"
XP_016980346.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016988421.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772	"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling"
XP_044316198.1	20	Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110320	"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH"
XP_016986178.1	7	KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2	"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_044312455.1	5	Reactome: R-HSA-4641263;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-5340588;Reactome: R-HSA-3772470	"Regulation of FZD by ubiquitination";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"RNF mutants show enhanced WNT signaling and proliferation";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_016979516.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016988690.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993	"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors"
XP_016985260.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_016974035.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619	"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN"
XP_016974381.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016986557.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016979993.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_016973922.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016969180.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_016981837.2	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_016975086.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_016975590.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425	"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_016986155.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016973749.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044315624.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_044314842.1	9	KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II"
XP_016986677.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_016972602.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016986524.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012	"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016987450.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044313802.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_016974769.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016975485.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044313698.1	11	Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378	"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling"
XP_044314514.1	11	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-163680;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Human cytomegalovirus infection";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_016984088.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016991500.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_044313815.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044316785.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016985210.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_016978986.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016985227.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016972741.2	6	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016970095.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016976315.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044317230.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_016986043.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016974368.1	4	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_044316041.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016986553.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016983565.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825	"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis"
XP_044314714.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_016983956.2	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016968984.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016978330.1	5	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_016969562.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016983514.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_016972308.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016980206.1	4	Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_016968989.2	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016974385.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016979193.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_044316529.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_016971639.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016979996.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016984420.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_016975389.1	9	Reactome: R-HSA-446353;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Cell-extracellular matrix interactions";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_016988170.2	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_016978616.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016977951.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016982845.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_044316920.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016984244.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016978775.2	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_044312812.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016991835.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016979988.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016982152.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_044316534.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_016988797.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016986592.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_016973420.1	7	MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;Reactome: R-HSA-1474151;MetaCyc: PWY-6614	"Folate transformations II (plants)";"Folate biosynthesis";"G1/S-Specific Transcription";"One carbon pool by folate";"Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis"
XP_016979351.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016983922.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_044317924.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016972538.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016968991.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016986753.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016970568.2	5	Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_016988094.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016984845.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_016984889.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_016968983.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016973926.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044315740.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_016973393.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016982383.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_016977113.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044314349.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016976630.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016973743.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_016971754.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_016971120.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346	"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Neddylation";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis"
XP_016976072.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events"
XP_016985561.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016982093.2	13	Reactome: R-HSA-6802948;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Signaling by high-kinase activity BRAF mutants";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Human papillomavirus infection";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_044312967.1	5	MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_016978566.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016991525.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016985323.1	14	Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-380284	"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_016977703.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_016973382.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016974633.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044316743.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016973248.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016983160.2	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation"
XP_044312763.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_044316233.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016987982.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016985228.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044315607.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016976295.2	17	KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7198	"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_044317327.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016984820.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_016989895.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016984705.1	9	Reactome: R-HSA-9656255;Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-9656256;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110357	"Defective OGG1 Substrate Binding";"Cleavage of the damaged purine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1"
XP_044317802.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_016974061.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016988387.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016982390.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016971759.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape"
XP_016990471.2	6	MetaCyc: PWY-5651;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_016969403.2	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_016980355.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016976979.1	9	Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-416482	"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"Rho GTPase cycle";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events"
XP_016970442.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016973397.2	3	Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681	"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling"
XP_016981509.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_016969648.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_044315362.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016982462.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952	"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions"
XP_016981610.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418597	"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"PKA activation";"G alpha (z) signalling events"
XP_044316536.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_016984907.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_016986867.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016969968.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016986616.2	3	MetaCyc: PWY-5698;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5697	"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_016990106.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759	"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors"
XP_044312413.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016980690.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016978954.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016990467.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016972507.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Glyphosate degradation III"
XP_016974891.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016987373.1	6	Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13	"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system"
XP_016981807.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016974512.1	5	Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3	"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_016987706.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044317355.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation"
XP_016986020.1	26	Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-918233	"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway"
XP_016992226.2	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_044317080.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016985048.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016984815.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_044312519.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_044316543.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling"
XP_016985391.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_044312454.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-3772470;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-4641262	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_044316867.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016983172.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016986312.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016970220.1	14	Reactome: R-HSA-75109;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4	"Triglyceride biosynthesis";"Synthesis of PE";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Synthesis of PC";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism"
XP_016984248.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016973380.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016978104.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_016988093.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_044315839.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044316881.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044316745.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016975310.1	10	KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;MetaCyc: PWY-7849;Reactome: R-HSA-2453902;MetaCyc: PWY-5691	"Purine metabolism";"Urate conversion to allantoin II";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Amyloid fiber formation";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin III";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I"
XP_016981503.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016985850.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016975581.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016971826.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016986306.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_016987616.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016989455.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016974047.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044314028.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_044317030.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016978907.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044314783.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016988095.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016969222.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_044316542.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway"
XP_016982568.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016988440.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761	"Neddylation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_016978659.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_044316509.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016990642.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016984753.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016980550.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_016979856.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_016977464.1	24	Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-418597	"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G alpha (z) signalling events"
XP_016989008.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_016979362.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016980342.1	4	MetaCyc: PWY-5874;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483	"Heme degradation I";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation"
XP_016981167.2	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_016984015.1	16	Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-164939;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-196025;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-437239	"Clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Nef mediated downregulation of CD28 cell surface expression";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Formation of annular gap junctions";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1"
XP_016979053.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_016974570.1	26	Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-8955332	"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Gap junction assembly";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Carboxyterminal post-translational modifications of tubulin"
XP_016979834.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044314025.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_016980485.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016990657.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016988246.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016990517.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016980021.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_016984232.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016983084.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016969896.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016973351.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016984165.2	3	MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262	"L-carnitine biosynthesis";"Lysine degradation";"Carnitine synthesis"
XP_016986759.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016988771.2	6	Reactome: R-HSA-416993;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-5099900	"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4"
XP_016972884.1	2	Reactome: R-HSA-9614657;Reactome: R-HSA-5205685	"FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy"
XP_016983941.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016977623.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_016977317.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016969929.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044317693.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016984905.1	7	MetaCyc: PWY-7255;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_044316341.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016991766.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044317340.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016983394.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016972061.2	4	MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_016974725.2	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016986556.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016978303.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016990095.2	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_016988100.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016969741.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044314274.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016981573.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_016990272.2	13	MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Methylaspartate cycle"
XP_016980135.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044312547.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-201722	"Ub-specific processing proteases";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex"
XP_016987567.1	5	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-901042	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle"
XP_016982814.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016974352.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016972459.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016980564.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016977618.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016990185.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_016975459.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016978862.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69017	"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6"
XP_016989012.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016977866.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016986760.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016989466.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016978055.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016977492.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016972885.1	2	Reactome: R-HSA-9614657;Reactome: R-HSA-5205685	"FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy"
XP_016981592.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016972690.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016984908.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_044316171.1	3	MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17	"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism"
XP_016990963.1	83	Reactome: R-HSA-5655291;Reactome: R-HSA-6807004;Reactome: R-HSA-9028335;Reactome: R-HSA-912526;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-5654704;Reactome: R-HSA-179812;Reactome: R-HSA-8851805;Reactome: R-HSA-5654719;Reactome: R-HSA-1236382;Reactome: R-HSA-74749;Reactome: R-HSA-112412;Reactome: R-HSA-5654699;Reactome: R-HSA-9034864;Reactome: R-HSA-5654727;Reactome: R-HSA-375165;Reactome: R-HSA-5654700;Reactome: R-HSA-167044;Reactome: R-HSA-2219530;Reactome: R-HSA-8983432;Reactome: R-HSA-1250196;Reactome: R-HSA-8875555;Reactome: R-HSA-389359;Reactome: R-HSA-9607240;Reactome: R-HSA-8856825;Reactome: R-HSA-1257604;Reactome: R-HSA-983695;Reactome: R-HSA-5654733;Reactome: R-HSA-5654710;Reactome: R-HSA-1963642;Reactome: R-HSA-5654720;Reactome: R-HSA-512988;Reactome: R-HSA-2871796;Reactome: R-HSA-5654689;Reactome: R-HSA-210993;Reactome: R-HSA-8865999;Reactome: R-HSA-2428933;Reactome: R-HSA-8875360;Reactome: R-HSA-2029482;Reactome: R-HSA-109704;Reactome: R-HSA-74751;Reactome: R-HSA-5655253;Reactome: R-HSA-9027284;Reactome: R-HSA-1433559;Reactome: R-HSA-180336;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-9026519;Reactome: R-HSA-5654732;Reactome: R-HSA-1250347;Reactome: R-HSA-2424491;Reactome: R-HSA-2730905;Reactome: R-HSA-8875656;Reactome: R-HSA-5654688;Reactome: R-HSA-5654712;Reactome: R-HSA-9645135;Reactome: R-HSA-5673001;Reactome: R-HSA-180292;Reactome: R-HSA-182971;Reactome: R-HSA-354194;Reactome: R-HSA-186763;Reactome: R-HSA-2179392;Reactome: R-HSA-912631;Reactome: R-HSA-9028731;Reactome: R-HSA-391160;Reactome: R-HSA-8853338;Reactome: R-HSA-1433557;Reactome: R-HSA-8851907;Reactome: R-HSA-8853334;Reactome: R-HSA-5654726;Reactome: R-HSA-5637810;Reactome: R-HSA-5654693;Reactome: R-HSA-5655302;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-2871809;Reactome: R-HSA-1295596;Reactome: R-HSA-5654706;Reactome: R-HSA-1839117;Reactome: R-HSA-5654695;Reactome: R-HSA-1963640	"Signaling by FGFR4 in disease";"Negative regulation of MET activity";"Activated NTRK2 signals through PI3K";"Interleukin receptor SHC signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"SHC-mediated cascade:FGFR3";"GRB2 events in EGFR signaling";"MET activates RAS signaling";"SHC-mediated cascade:FGFR4";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signal attenuation";"SOS-mediated signalling";"SHC-mediated cascade:FGFR2";"Activated NTRK3 signals through RAS";"Negative regulation of FGFR2 signaling";"NCAM signaling for neurite out-growth";"FRS-mediated FGFR2 signaling";"Signalling to RAS";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-15 signaling";"SHC1 events in ERBB2 signaling";"MET activates RAP1 and RAC1";"CD28 dependent Vav1 pathway";"FLT3 Signaling";"Cargo recognition for clathrin-mediated endocytosis";"PIP3 activates AKT signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR3";"PI3K events in ERBB2 signaling";"PI-3K cascade:FGFR4";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"FCERI mediated MAPK activation";"PI-3K cascade:FGFR1";"Tie2 Signaling";"MET activates PTPN11";"SHC-related events triggered by IGF1R";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of actin dynamics for phagocytic cup formation";"PI3K Cascade";"Insulin receptor signalling cascade";"Signaling by FGFR2 in disease";"Erythropoietin activates RAS";"Regulation of KIT signaling";"SHC1 events in EGFR signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR3 signaling";"SHC1 events in ERBB4 signaling";"DAP12 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"MET receptor recycling";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR4 signaling";"STAT5 Activation";"RAF/MAP kinase cascade";"GAB1 signalosome";"EGFR downregulation";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Downstream signal transduction";"EGFR Transactivation by Gastrin";"Regulation of signaling by CBL";"Activated NTRK2 signals through FRS2 and FRS3";"Signal regulatory protein family interactions";"Signaling by FGFR3 point mutants in cancer";"Signaling by SCF-KIT";"MET activates PI3K/AKT signaling";"Signaling by FGFR3 fusions in cancer";"Negative regulation of FGFR1 signaling";"Constitutive Signaling by EGFRvIII";"FRS-mediated FGFR1 signaling";"Signaling by FGFR1 in disease";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"FCERI mediated Ca+2 mobilization";"Spry regulation of FGF signaling";"FRS-mediated FGFR3 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"PI-3K cascade:FGFR2";"GRB2 events in ERBB2 signaling"
XP_016975507.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_016982164.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_016979211.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016970553.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016984756.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016989556.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_016987261.2	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_016974655.2	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044313355.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016977557.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016968870.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592	"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1"
XP_016980227.2	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016978857.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
XP_016988650.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5689880	"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ub-specific processing proteases"
XP_016973862.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016977943.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016978325.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1"
XP_044313816.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044313943.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination"
XP_016986918.2	12	Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982	"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_016970969.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016986701.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016984593.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-983168	"Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016980942.2	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_016983442.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_016985301.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3	"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism"
XP_016986862.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016975264.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_016982781.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_044315644.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044313079.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016977965.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016978437.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016977982.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-195253	"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex"
XP_016982389.1	3	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_016976594.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_016976060.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_016980243.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016987389.2	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016988188.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016986942.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_016973536.2	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016989982.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044317556.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016987548.2	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_016991501.1	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation"
XP_016982066.1	8	MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826	"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Neutrophil degranulation";"Surfactant metabolism"
XP_016982704.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_044317520.1	3	MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001	"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis";"Sialic acid metabolism"
XP_016972574.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_016974345.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016987985.1	179	Reactome: R-HSA-68949;Reactome: R-HSA-2644606;Reactome: R-HSA-6804757;Reactome: R-HSA-9637628;Reactome: R-HSA-6782135;Reactome: R-HSA-4641257;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-1169091;Reactome: R-HSA-2173791;Reactome: R-HSA-400253;Reactome: R-HSA-6782210;Reactome: R-HSA-3134975;Reactome: R-HSA-110314;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-2122947;Reactome: R-HSA-68827;Reactome: R-HSA-901032;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-917729;Reactome: R-HSA-174048;Reactome: R-HSA-8948747;Reactome: R-HSA-3322077;Reactome: R-HSA-382556;Reactome: R-HSA-9033241;Reactome: R-HSA-5607761;Reactome: R-HSA-975163;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-192823;Reactome: R-HSA-3769402;Reactome: R-HSA-5689901;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-182971;Reactome: R-HSA-2691232;Reactome: R-HSA-4608870;Reactome: R-HSA-168638;Reactome: R-HSA-8849469;Reactome: R-HSA-450321;Reactome: R-HSA-2559582;Reactome: R-HSA-937072;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-1799339;Reactome: R-HSA-8939236;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-9020702;Reactome: R-HSA-6804756;Reactome: R-HSA-5675482;Reactome: R-HSA-2894862;Reactome: R-HSA-9010553;Reactome: R-HSA-209560;Reactome: R-HSA-9013973;Reactome: R-HSA-5689896;Reactome: R-HSA-6781827;Reactome: R-HSA-5654733;Reactome: R-HSA-975110;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-2408557;Reactome: R-HSA-5656169;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-532668;Reactome: R-HSA-2559580;Reactome: R-HSA-162588;Reactome: R-HSA-5689880;Reactome: R-HSA-2173795;Reactome: R-HSA-1236974;Reactome: R-HSA-6807004;Reactome: R-HSA-110312;Reactome: R-HSA-2173796;Reactome: R-HSA-205043;Reactome: R-HSA-1236382;Reactome: R-HSA-5696395;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-1358803;Reactome: R-HSA-2559585;Reactome: R-HSA-1253288;Reactome: R-HSA-4641263;Reactome: R-HSA-9615710;Reactome: R-HSA-975957;Reactome: R-HSA-5693607;Reactome: R-HSA-5676590;Reactome: R-HSA-8866654;Reactome: R-HSA-5687128;Reactome: R-HSA-2122948;Reactome: R-HSA-156902;Reactome: R-HSA-8876493;Reactome: R-HSA-195253;Reactome: R-HSA-5654726;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-9633012;Reactome: R-HSA-8948751;Reactome: R-HSA-209543;Reactome: R-HSA-5632684;Reactome: R-HSA-201681;Reactome: R-HSA-5668541;Reactome: R-HSA-5675221;Reactome: R-HSA-69481;Reactome: R-HSA-8863795;Reactome: R-HSA-211733;Reactome: R-HSA-1295596;Reactome: R-HSA-174490;Reactome: R-HSA-174178;Reactome: R-HSA-917937;Reactome: R-HSA-8856828;Reactome: R-HSA-5654732;Reactome: R-HSA-4641258;Reactome: R-HSA-937039;Reactome: R-HSA-202424;Reactome: R-HSA-9013507;Reactome: R-HSA-5693565;Reactome: R-HSA-9645460;Reactome: R-HSA-2467813;Reactome: R-HSA-9636383;Reactome: R-HSA-912631;Reactome: R-HSA-5205685;Reactome: R-HSA-9604323;Reactome: R-HSA-168927;Reactome: R-HSA-5357905;Reactome: R-HSA-72764;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-936440;Reactome: R-HSA-9646399;Reactome: R-HSA-975144;Reactome: R-HSA-5655862;Reactome: R-HSA-175474;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-6791226;Reactome: R-HSA-69231;Reactome: R-HSA-72689;Reactome: R-HSA-8866652;Reactome: R-HSA-8875360;Reactome: R-HSA-5362768;Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;Reactome: R-HSA-5678895;Reactome: R-HSA-936964;Reactome: R-HSA-5689877;Reactome: R-HSA-5610785;Reactome: R-HSA-937042;Reactome: R-HSA-187577;Reactome: R-HSA-2672351;Reactome: R-HSA-168928;Reactome: R-HSA-977225;Reactome: R-HSA-5696400;Reactome: R-HSA-937041;Reactome: R-HSA-6783310;Reactome: R-HSA-5357956;Reactome: R-HSA-975956;Reactome: R-HSA-5696394;Reactome: R-HSA-349425;Reactome: R-HSA-156827;Reactome: R-HSA-5696397;Reactome: R-HSA-9014325;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-69541;Reactome: R-HSA-2173788;Reactome: R-HSA-2979096;Reactome: R-HSA-5654727;Reactome: R-HSA-450302;Reactome: R-HSA-5684264;Reactome: R-HSA-5658442;Reactome: R-HSA-9613829;Reactome: R-HSA-3785653;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783	"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of TP53 Degradation";"Modulation by Mtb of host immune system";"Dual incision in TC-NER";"Degradation of AXIN";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of NF-kappaB in B cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Circadian Clock";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of innate immune responses to cytosolic DNA";"Recognition of DNA damage by PCNA-containing replication complex";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NOTCH1 Intracellular Domain Regulates Transcription";"CDT1 association with the CDC6:ORC:origin complex";"ER Quality Control Compartment (ERQC)";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Endosomal Sorting Complex Required For Transport (ESCRT)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of PTEN localization";"Glycogen synthesis";"ABC-family proteins mediated transport";"Peroxisomal protein import";"Dectin-1 mediated noncanonical NF-kB signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Viral mRNA Translation";"Deactivation of the beta-catenin transactivating complex";"Metalloprotease DUBs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"EGFR downregulation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Asymmetric localization of PCP proteins";"NOD1/2 Signaling Pathway";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Senescence-Associated Secretory Phenotype (SASP)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"SRP-dependent cotranslational protein targeting to membrane";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Interleukin-1 signaling";"Regulation of TP53 Activity through Phosphorylation";"Regulation of necroptotic cell death";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of expression of SLITs and ROBOs";"NF-kB is activated and signals survival";"TICAM1-dependent activation of IRF3/IRF7";"Ovarian tumor domain proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Negative regulation of FGFR4 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Selenocysteine synthesis";"Termination of translesion DNA synthesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"UCH proteinases";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Oxidative Stress Induced Senescence";"Budding and maturation of HIV virion";"Ub-specific processing proteases";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"ER-Phagosome pathway";"Negative regulation of MET activity";"Translesion synthesis by REV1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NRIF signals cell death from the nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Formation of Incision Complex in GG-NER";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Downregulation of ERBB2:ERBB3 signaling";"Oncogene Induced Senescence";"Downregulation of ERBB4 signaling";"Regulation of FZD by ubiquitination";"Late endosomal microautophagy";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of DNA double-strand break ends";"NIK-->noncanonical NF-kB signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"MAPK6/MAPK4 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Peptide chain elongation";"InlA-mediated entry of Listeria monocytogenes into host cells";"Degradation of beta-catenin by the destruction complex";"Negative regulation of FGFR1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of PTEN stability and activity";"p75NTR recruits signalling complexes";"Hedgehog 'on' state";"TCF dependent signaling in response to WNT";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of MAPK pathway";"G2/M Checkpoints";"Downregulation of ERBB2 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Spry regulation of FGF signaling";"Membrane binding and targetting of GAG proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Iron uptake and transport";"Clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"Degradation of DVL";"IRAK1 recruits IKK complex";"Downstream TCR signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Alpha-protein kinase 1 signaling pathway";"Separation of Sister Chromatids";"Prevention of phagosomal-lysosomal fusion";"Regulation of signaling by CBL";"Pink/Parkin Mediated Mitophagy";"Negative regulation of NOTCH4 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of TNFR1 signaling";"Eukaryotic Translation Termination";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Negative regulators of DDX58/IFIH1 signaling";"Aggrephagy";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Translesion synthesis by POLK";"Assembly Of The HIV Virion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Major pathway of rRNA processing in the nucleolus and cytosol";"Cyclin D associated events in G1";"Formation of a pool of free 40S subunits";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"InlB-mediated entry of Listeria monocytogenes into host cell";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"Defective CFTR causes cystic fibrosis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Josephin domain DUBs";"GLI3 is processed to GLI3R by the proteasome";"IRAK2 mediated activation of TAK1 complex";"SCF(Skp2)-mediated degradation of p27/p21";"Stimuli-sensing channels";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amyloid fiber formation";"Dual Incision in GG-NER";"IKK complex recruitment mediated by RIP1";"Fanconi Anemia Pathway";"TNFR1-induced NFkappaB signaling pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"DNA Damage Recognition in GG-NER";"Autodegradation of the E3 ubiquitin ligase COP1";"L13a-mediated translational silencing of Ceruloplasmin expression";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Stabilization of p53";"Downregulation of TGF-beta receptor signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR2 signaling";"activated TAK1 mediates p38 MAPK activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RAS by GAPs";"Chaperone Mediated Autophagy";"Myoclonic epilepsy of Lafora";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome"
XP_016978882.1	13	KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1	"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione metabolism"
XP_016975948.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044314345.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016990755.1	7	MetaCyc: PWY-6737;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6724;MetaCyc: PWY-7238	"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation II";"Sucrose biosynthesis II"
XP_016980926.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_044313832.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016970284.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016988386.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016979125.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016980454.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_044317313.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016985095.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_016987234.2	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_016973758.1	9	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016972356.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044316527.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_044313558.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016991201.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016985676.1	13	Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-437239	"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1"
XP_016991301.2	56	Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-5689880	"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases"
XP_016992053.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_016973956.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016974870.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044314764.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016973591.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016975129.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016979596.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_044314354.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016990448.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5664	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_016987663.1	31	Reactome: R-HSA-163765;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWYG-321;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-6282;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-5994;MetaCyc: PWY-5973;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-6113	"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis"
XP_044316790.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016989084.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016985484.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016990813.2	15	MetaCyc: PWY-7383;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7218;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901	"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Purine metabolism";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation"
XP_016978516.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_016972201.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_044314322.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016978069.1	10	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"RSK activation";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_044313430.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016975039.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257	"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN"
XP_016978608.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016979382.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016979117.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982114.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044312418.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016974037.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785	"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome"
XP_044312795.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016971290.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016971463.1	34	Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-9639288;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amino acids regulate mTORC1";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_044315293.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016980736.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_016977963.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016969923.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044316890.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016978921.1	13	MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969	"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_016986966.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation"
XP_016988352.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_016989751.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016982539.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016984710.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_016970867.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_016985637.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016988509.2	8	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_016979145.1	6	Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016980706.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178	"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_044312831.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_044313699.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"PKA activation in glucagon signalling";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events"
XP_016976412.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016988416.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_044313167.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016977556.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016984200.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016977850.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016972502.1	8	KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism"
XP_016984653.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_016976605.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016975930.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044314325.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016990774.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-5136	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_016970556.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016989234.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_016989600.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_044317165.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016970268.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_016978922.1	13	KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5538	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI"
XP_044317557.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016986889.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016971593.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016980234.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016987646.1	4	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_016973579.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_044317603.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016983029.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_016971814.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_016969069.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016987264.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044316465.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016992308.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016982200.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044313561.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016985447.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016990039.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016977034.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016971366.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_016980650.2	10	MetaCyc: PWY-6554;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_016987300.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016980059.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016974372.1	7	Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-114608	"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Platelet degranulation"
XP_016979292.1	4	MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59	"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_044312588.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016981468.2	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_044312849.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_016969970.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016973376.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016979190.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_016978617.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016980175.1	3	Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_044316523.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016974219.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016974393.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016975608.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_016979639.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016982334.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044315934.1	22	MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7602;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7606;MetaCyc: PWY-6958;MetaCyc: PWY-7728;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7049;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7592;MetaCyc: PWY-7724;MetaCyc: PWY-7053	"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)"
XP_016984633.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016975111.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016991188.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_044312517.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_016979728.2	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_016982458.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016972298.2	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_016980281.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016977604.1	182	Reactome: R-HSA-5654727;Reactome: R-HSA-450302;Reactome: R-HSA-5658442;Reactome: R-HSA-5684264;Reactome: R-HSA-9613829;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-3785653;Reactome: R-HSA-937041;Reactome: R-HSA-5696394;Reactome: R-HSA-349425;Reactome: R-HSA-6783310;Reactome: R-HSA-5357956;Reactome: R-HSA-975956;Reactome: R-HSA-9014325;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-156827;Reactome: R-HSA-5696397;Reactome: R-HSA-69541;Reactome: R-HSA-2173788;Reactome: R-HSA-2979096;Reactome: R-HSA-8875360;Reactome: R-HSA-72689;Reactome: R-HSA-8866652;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-936964;Reactome: R-HSA-5362768;Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;Reactome: R-HSA-168928;Reactome: R-HSA-5696400;Reactome: R-HSA-977225;Reactome: R-HSA-5610785;Reactome: R-HSA-2672351;Reactome: R-HSA-937042;Reactome: R-HSA-187577;Reactome: R-HSA-5357905;Reactome: R-HSA-9646399;Reactome: R-HSA-936440;Reactome: R-HSA-72764;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-5655862;Reactome: R-HSA-175474;Reactome: R-HSA-69601;Reactome: R-HSA-975144;Reactome: R-HSA-69231;Reactome: R-HSA-8852276;Reactome: R-HSA-6791226;Reactome: R-HSA-2467813;Reactome: R-HSA-912631;Reactome: R-HSA-5205685;Reactome: R-HSA-72649;Reactome: R-HSA-9636383;Reactome: R-HSA-9604323;Reactome: R-HSA-168927;Reactome: R-HSA-917937;Reactome: R-HSA-5654732;Reactome: R-HSA-8856828;Reactome: R-HSA-9013507;Reactome: R-HSA-202424;Reactome: R-HSA-937039;Reactome: R-HSA-4641258;Reactome: R-HSA-9645460;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8863795;Reactome: R-HSA-174178;Reactome: R-HSA-1295596;Reactome: R-HSA-174490;Reactome: R-HSA-5687128;Reactome: R-HSA-2122948;Reactome: R-HSA-5693607;Reactome: R-HSA-8866654;Reactome: R-HSA-5676590;Reactome: R-HSA-8876493;Reactome: R-HSA-156902;Reactome: R-HSA-445989;Reactome: R-HSA-8948751;Reactome: R-HSA-9633012;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5654726;Reactome: R-HSA-201681;Reactome: R-HSA-5668541;Reactome: R-HSA-72702;Reactome: R-HSA-209543;Reactome: R-HSA-5632684;Reactome: R-HSA-1358803;Reactome: R-HSA-2559585;Reactome: R-HSA-1253288;Reactome: R-HSA-4641263;Reactome: R-HSA-975957;Reactome: R-HSA-9615710;Reactome: R-HSA-5689880;Reactome: R-HSA-2559580;Reactome: R-HSA-162588;Reactome: R-HSA-2173795;Reactome: R-HSA-1236974;Reactome: R-HSA-6807004;Reactome: R-HSA-110312;Reactome: R-HSA-5696395;Reactome: R-HSA-174184;Reactome: R-HSA-205043;Reactome: R-HSA-2173796;Reactome: R-HSA-1236382;Reactome: R-HSA-2871837;Reactome: R-HSA-2408557;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5656169;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-532668;Reactome: R-HSA-72695;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8939236;Reactome: R-HSA-1799339;Reactome: R-HSA-6804756;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-5675482;Reactome: R-HSA-5689896;Reactome: R-HSA-9013973;Reactome: R-HSA-5654733;Reactome: R-HSA-975110;Reactome: R-HSA-6781827;Reactome: R-HSA-209560;Reactome: R-HSA-9010553;Reactome: R-HSA-168638;Reactome: R-HSA-174113;Reactome: R-HSA-2691232;Reactome: R-HSA-182971;Reactome: R-HSA-4608870;Reactome: R-HSA-450321;Reactome: R-HSA-8849469;Reactome: R-HSA-2559582;Reactome: R-HSA-937072;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-3322077;Reactome: R-HSA-8948747;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-9033241;Reactome: R-HSA-5656121;Reactome: R-HSA-975163;Reactome: R-HSA-3769402;Reactome: R-HSA-5689901;Reactome: R-HSA-8854050;Reactome: R-HSA-110320;Reactome: R-HSA-192823;Reactome: R-HSA-450408;Reactome: R-HSA-2122947;Reactome: R-HSA-110314;Reactome: R-HSA-3134975;Reactome: R-HSA-180534;Reactome: R-HSA-901032;Reactome: R-HSA-68827;Reactome: R-HSA-917729;Reactome: R-HSA-174048;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-6804757;Reactome: R-HSA-2644606;Reactome: R-HSA-9637628;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-6782135;Reactome: R-HSA-1169408;Reactome: R-HSA-6782210;Reactome: R-HSA-72706;Reactome: R-HSA-1169091;Reactome: R-HSA-2173791;Reactome: R-HSA-400253	"Negative regulation of FGFR2 signaling";"activated TAK1 mediates p38 MAPK activation";"Regulation of RAS by GAPs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Chaperone Mediated Autophagy";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Myoclonic epilepsy of Lafora";"IKK complex recruitment mediated by RIP1";"DNA Damage Recognition in GG-NER";"Autodegradation of the E3 ubiquitin ligase COP1";"Fanconi Anemia Pathway";"TNFR1-induced NFkappaB signaling pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"L13a-mediated translational silencing of Ceruloplasmin expression";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Stabilization of p53";"Downregulation of TGF-beta receptor signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"InlB-mediated entry of Listeria monocytogenes into host cell";"Formation of a pool of free 40S subunits";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Dual Incision in GG-NER";"Amyloid fiber formation";"GLI3 is processed to GLI3R by the proteasome";"Stimuli-sensing channels";"IRAK2 mediated activation of TAK1 complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of TNFR1 signaling";"Aggrephagy";"Negative regulators of DDX58/IFIH1 signaling";"Eukaryotic Translation Termination";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Translesion synthesis by POLK";"Assembly Of The HIV Virion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Cyclin D associated events in G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Major pathway of rRNA processing in the nucleolus and cytosol";"Separation of Sister Chromatids";"Regulation of signaling by CBL";"Pink/Parkin Mediated Mitophagy";"Translation initiation complex formation";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of NOTCH4 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Iron uptake and transport";"Negative regulation of FGFR3 signaling";"Clathrin-mediated endocytosis";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Downstream TCR signaling";"IRAK1 recruits IKK complex";"Degradation of DVL";"Alpha-protein kinase 1 signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downregulation of ERBB2 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Spry regulation of FGF signaling";"Membrane binding and targetting of GAG proteins";"MAPK6/MAPK4 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Processing of DNA double-strand break ends";"E3 ubiquitin ligases ubiquitinate target proteins";"NIK-->noncanonical NF-kB signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Peptide chain elongation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of PTEN stability and activity";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Negative regulation of FGFR1 signaling";"TCF dependent signaling in response to WNT";"TNFR2 non-canonical NF-kB pathway";"Ribosomal scanning and start codon recognition";"p75NTR recruits signalling complexes";"Hedgehog 'on' state";"Downregulation of ERBB2:ERBB3 signaling";"Oncogene Induced Senescence";"Downregulation of ERBB4 signaling";"Regulation of FZD by ubiquitination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Late endosomal microautophagy";"Ub-specific processing proteases";"Oxidative Stress Induced Senescence";"Budding and maturation of HIV virion";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"ER-Phagosome pathway";"Negative regulation of MET activity";"Translesion synthesis by REV1";"Formation of Incision Complex in GG-NER";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NRIF signals cell death from the nucleus";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"FCERI mediated NF-kB activation";"Selenocysteine synthesis";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Termination of translesion DNA synthesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"UCH proteinases";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of the ternary complex, and subsequently, the 43S complex";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of TP53 Activity through Phosphorylation";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of necroptotic cell death";"Ovarian tumor domain proteases";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulation of FGFR4 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NF-kB is activated and signals survival";"Regulation of expression of SLITs and ROBOs";"NOD1/2 Signaling Pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"EGFR downregulation";"Asymmetric localization of PCP proteins";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Senescence-Associated Secretory Phenotype (SASP)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Glycogen synthesis";"Regulation of PTEN localization";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Peroxisomal protein import";"Translesion synthesis by POLI";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Deactivation of the beta-catenin transactivating complex";"Metalloprotease DUBs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Translesion Synthesis by POLH";"Viral mRNA Translation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NOTCH1 Intracellular Domain Regulates Transcription";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of innate immune responses to cytosolic DNA";"Vpu mediated degradation of CD4";"ER Quality Control Compartment (ERQC)";"CDT1 association with the CDC6:ORC:origin complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of TP53 Degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Modulation by Mtb of host immune system";"Orc1 removal from chromatin";"Degradation of AXIN";"Dual incision in TC-NER";"ISG15 antiviral mechanism";"Gap-filling DNA repair synthesis and ligation in TC-NER";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of NF-kappaB in B cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Circadian Clock"
XP_016975082.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_016987091.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-5619078;Reactome: R-HSA-727802	"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars"
XP_016981111.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016985520.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1"
XP_016988361.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016977480.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-7587	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)"
XP_016988247.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016986202.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016984761.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044314086.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_016973426.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_016971273.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_016980314.2	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_016985627.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_044316829.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016984095.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289	"Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_044317381.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016976798.1	27	Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-975957;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-9010553;Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-167200;Reactome: R-HSA-159231;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-975956;Reactome: R-HSA-159227;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Regulation of expression of SLITs and ROBOs";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of the SLBP independent Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
XP_016981163.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016980049.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_016989103.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044315677.1	17	KEGG: 04926+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-1433557;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-69601;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Transcriptional Regulation by E2F6";"Signaling by SCF-KIT";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis"
XP_016991487.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_044317272.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_044317312.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044314534.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044314533.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016971359.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016970493.1	13	Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828	"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis"
XP_016988744.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_044313360.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044315436.1	42	Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-2299718;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-73728;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-3214815;Reactome: R-HSA-5693565;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582	"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Late Events";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Condensation of Prophase Chromosomes";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Opening";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"DNA methylation";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)"
XP_016982168.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016982295.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_016970019.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016984367.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016969064.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016986773.1	17	Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880	"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"Ub-specific processing proteases"
XP_016969324.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044317512.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016972204.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016987665.1	31	Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-6282;MetaCyc: PWY-5989;Reactome: R-HSA-163765;MetaCyc: PWY-5142;Reactome: R-HSA-199220;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-5994;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5971;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-8012;MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence"
XP_016971725.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016977004.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016984250.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044314864.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016989750.2	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_044312451.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_016975966.1	6	Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-2173788	"Regulation of PTEN stability and activity";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling"
XP_016977981.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-195253	"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex"
XP_016990860.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016972754.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016983695.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
XP_016990645.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016969706.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016984892.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016978634.1	7	MetaCyc: PWY-8004;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;Reactome: R-HSA-71336;MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31	"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Chitin derivatives degradation";"Pentose phosphate pathway"
XP_016978545.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_016978432.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044315724.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_016975596.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7036	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_044317718.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016977614.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_016986049.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977205.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016991372.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044315578.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation"
XP_016975089.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_044315002.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_016988750.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016973128.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016973763.2	9	MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7117	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_044314448.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016979192.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_016985071.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044314189.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_016973522.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_044312506.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016985214.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_016988812.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-6798695;Reactome: R-HSA-111458	"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Neutrophil degranulation";"Formation of apoptosome"
XP_016984174.2	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_016983040.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_016973550.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190861	"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly"
XP_016976414.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016988753.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016973026.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway"
XP_016991023.2	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016982014.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_016983547.2	11	Reactome: R-HSA-74259;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-5497;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4	"Purine catabolism";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Purine metabolism"
XP_016981572.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_016984406.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016990529.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016969062.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016969374.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016985556.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_016977772.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044316804.1	5	MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_016980349.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044315055.1	7	Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034	"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np"
XP_016975543.1	3	MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57	"Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism"
XP_016981388.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044316442.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_016977085.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044314344.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897	"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carnitine metabolism";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes"
XP_016978023.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016982740.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_044315026.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016968872.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_016987098.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_044317339.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016970779.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016986643.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-881907	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK"
XP_016972621.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_044312401.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016988891.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_044312587.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016969703.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016972262.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016971655.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-211976	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols"
XP_016980509.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016992302.2	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_016990228.2	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016970264.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_016976745.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044317450.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_044316883.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044313347.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_044314587.1	7	Reactome: R-HSA-212676;Reactome: R-HSA-373753;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-3000170;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Dopamine Neurotransmitter Release Cycle";"Nephrin family interactions";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Syndecan interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016971782.2	13	MetaCyc: PWY-7184;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7222	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_016991439.1	3	Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_016972967.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016980941.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_016982908.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_044313364.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_016991880.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016980576.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016984500.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016969721.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_016973390.2	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_016978036.2	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016980649.2	10	Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6554;MetaCyc: PWY-6369;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-4661	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_016981371.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044316902.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016990269.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128	"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling"
XP_044314702.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016983510.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation"
XP_044316257.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_044315911.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_044317214.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016978621.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016971101.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016977045.2	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_016976865.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016980169.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016989059.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016981500.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_016986926.2	12	Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"NrCAM interactions";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_044314715.1	6	Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_016974365.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_016985633.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016981924.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044316748.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_016986225.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_016982112.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-73614;MetaCyc: PWY-6556;MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-7199	"Neutrophil degranulation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage"
XP_016968868.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_016982735.1	6	MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_044316486.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_016976764.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016969518.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016978177.1	5	Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9648895	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_016981246.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016991629.1	6	MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5744	"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation"
XP_016990752.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016991499.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_016974900.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_016974096.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_016986876.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016975119.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016975446.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016989283.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044316338.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016979260.2	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_016988112.2	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016988562.1	26	Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082	"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Attenuation phase";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression"
XP_016991143.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044316871.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016977843.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016975073.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016986766.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016985900.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016991973.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044312802.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_016977837.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044317677.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_016970155.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044315858.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016985286.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_016973075.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016977320.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016971648.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016986221.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044314829.1	12	MetaCyc: PWY-2821;MetaCyc: PWY-801;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-601;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7	"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Tryptophan metabolism"
XP_044316716.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044314860.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_016976138.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016987902.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044317390.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016973566.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_016970914.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_016984307.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_016972961.1	6	Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044316044.1	42	Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-5693565;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-73728;Reactome: R-HSA-5625886;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-73772;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-427359;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718	"Packaging Of Telomere Ends";"Meiotic synapsis";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"RNA Polymerase I Promoter Escape";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"DNA methylation";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"HCMV Late Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"Meiotic recombination";"Cleavage of the damaged purine";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Condensation of Prophase Chromosomes"
XP_016971980.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_016983945.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016985652.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684	"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state"
XP_016973126.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016980823.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016981147.1	14	Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1	"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate";"Methane metabolism";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glycine betaine degradation I";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism"
XP_044315853.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016982596.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016969942.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_016978068.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016977592.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016985625.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism"
XP_016982623.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016969326.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016989092.2	4	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_044316859.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016976713.1	8	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy"
XP_016986039.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016976021.2	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016987952.2	7	KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_044316887.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016971417.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044314117.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes"
XP_044313934.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016970765.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016974956.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016986138.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_044316700.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_044315869.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016990392.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016982197.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016980294.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016973015.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_016974561.2	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_016975196.1	2	MetaCyc: PWY-8061;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins"
XP_044315650.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044314623.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016978648.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_016974095.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_044317166.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016979761.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway"
XP_016980660.1	7	Reactome: R-HSA-8856828;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_016973246.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016985972.1	8	MetaCyc: PWY-7210;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_016971364.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016976157.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016974052.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_016973890.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016975266.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_016981029.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016978662.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016977697.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_016980704.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016989858.2	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_016982730.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_044312819.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016982987.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016984712.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion"
XP_016981031.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016971112.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_016989429.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_016985327.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044314765.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016977377.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_016976062.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_016977267.2	11	Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-5668599;KEGG: 04070+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;MetaCyc: PWY-6352;Reactome: R-HSA-1660499	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"RHO GTPases Activate NADPH Oxidases";"Phosphatidylinositol signaling system";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane"
XP_016989583.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_044317978.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044313313.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016990038.2	6	MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166	"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA"
XP_016982531.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016973357.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016983148.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_044316827.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_044314579.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016980237.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016975482.1	40	Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"mRNA Capping";"Pausing and recovery of HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis"
XP_016981621.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway"
XP_016970734.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016988900.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-7900;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-3878781	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen storage disease type IV (GBE1)"
XP_016983404.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016987003.1	11	MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6963;MetaCyc: PWY-6964	"L-glutamine biosynthesis III";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II"
XP_016988781.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016978881.1	13	Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370	"Glutathione conjugation";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)"
XP_016989923.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016972816.2	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016982185.2	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_016974376.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191	"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Neutrophil degranulation";"Synthesis of PC"
XP_016989757.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3656532;Reactome: R-HSA-3642279;Reactome: R-HSA-2173789	"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 KD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_016979847.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979833.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_016981389.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-68952	"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation"
XP_044312816.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016969637.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016988415.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination"
XP_016983902.2	8	Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187	"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress"
XP_016990248.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979804.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016992250.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_044313115.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016974481.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016987644.1	4	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_016970957.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_016984094.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis"
XP_016975041.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044313280.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016985200.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044317762.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_044313311.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016980545.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016986003.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044315773.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016980744.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943	"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates"
XP_016970649.2	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_016988106.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016991166.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_016972965.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044317352.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016970436.1	13	MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5	"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_016977659.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC"
XP_016985437.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016987927.1	11	Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781	"Nuclear Receptor transcription pathway";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression"
XP_044316771.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016984408.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_016982928.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044316084.1	42	Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-73728	"Amyloid fiber formation";"Cleavage of the damaged purine";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"HCMV Late Events";"PRC2 methylates histones and DNA";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"DNA methylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"RNA Polymerase I Promoter Opening"
XP_044317115.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_016990110.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors"
XP_016983452.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016971241.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044314881.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_016974054.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_016977561.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_016980493.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044317347.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016973981.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016974081.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_016978210.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016990724.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016982570.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016979840.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;MetaCyc: PWY-7511	"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination"
XP_016981235.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044317508.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044313077.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016976609.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016972880.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044312821.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016978924.1	13	KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5537;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5538	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI"
XP_016979291.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59	"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism"
XP_016970997.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_016989729.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_016978912.1	8	KEGG: 00350+1.14.16.2;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;MetaCyc: PWY-5394;MetaCyc: PWY-3581;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2	"Tyrosine metabolism";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis I";"Catecholamine biosynthesis";"Folate biosynthesis"
XP_016985540.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016969902.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016981484.2	12	MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672	"Chitin degradation to ethanol";"Methane metabolism";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Cis-genanyl-coa degradation"
XP_044314604.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_016977221.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_016969950.1	10	MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781	"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Butanoate metabolism";"PPARA activates gene expression"
XP_016971598.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016980825.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016977669.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016977200.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016990144.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016991343.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-73762	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_044315828.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016975320.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016990667.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_044314526.1	5	Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;Reactome: R-HSA-9033500;MetaCyc: PWY-7782	"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis"
XP_044313158.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016984394.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016969227.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016987725.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016976795.1	7	Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1	"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)"
XP_044312426.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016988186.2	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_016989316.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_016970821.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764	"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling"
XP_016986917.1	8	Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001	"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade"
XP_016990531.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016983584.1	24	Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-6814122	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016969947.1	10	MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10	"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Butanoate metabolism";"PPARA activates gene expression";"Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies"
XP_016971760.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape"
XP_016972764.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_016974370.1	7	Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381183	"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Platelet degranulation";"PERK regulates gene expression";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_016990933.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016987501.1	6	Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978	"Galactose catabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia"
XP_044313906.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016973876.1	8	Reactome: R-HSA-70635;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-4983;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5;MetaCyc: PWY-5154;MetaCyc: PWY-4984	"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle"
XP_044317341.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016982828.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_016975563.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016987507.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016976870.1	60	MetaCyc: PWY-5138;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;Reactome: R-HSA-77305;MetaCyc: PWY-6944;MetaCyc: PWY-5789;Reactome: R-HSA-77348;KEGG: 00280+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-6946;MetaCyc: PWY-6883;KEGG: 00720+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00310+4.2.1.17;KEGG: 00362+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7656;KEGG: 00281+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;MetaCyc: PWY-7094;KEGG: 00930+4.2.1.17;Reactome: R-HSA-77285;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;MetaCyc: PWY-5109;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00623+1.1.1.35;Reactome: R-HSA-77310;MetaCyc: PWY-7778;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-1361;Reactome: R-HSA-1482798;MetaCyc: PWY-7654;Reactome: R-HSA-77288;MetaCyc: PWY-5177;KEGG: 00640+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7007;MetaCyc: PWY-6583	"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Valine, leucine and isoleucine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"Carbon fixation pathways in prokaryotes";"Aminobenzoate degradation";"Fatty acid degradation";"Lysine degradation";"Benzoate degradation";"beta-Alanine metabolism";"Methyl tert-butyl ether degradation";"Tryptophan metabolism";"Spodoptera littoralis pheromone biosynthesis";"Geraniol degradation";"Limonene and pinene degradation";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid salvage";"Caprolactam degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Butanoate metabolism";"Fatty acid elongation";"Benzoate degradation";"Fatty acid degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fermentation to 2-methylbutanoate";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"alpha-Linolenic acid metabolism";"Toluene degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"2-methylpropene degradation";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Acyl chain remodeling of CL";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Glutaryl-coa degradation";"Propanoate metabolism";"Caprolactam degradation";"Geraniol degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol I"
XP_016969179.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016985628.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_044314699.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_016969723.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016973295.1	16	MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7124;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-6886;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-7218	"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Glycolysis";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_016975779.2	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_016986137.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_016981886.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016970764.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016987412.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_016980966.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044316908.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016986709.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016976911.1	12	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Activation of AMPK downstream of NMDARs";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway"
XP_016980152.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016972184.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044314766.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016973669.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_016974036.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949	"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin"
XP_016979931.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016989284.1	6	Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3	"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_016981556.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044313460.1	13	MetaCyc: PWY-6842;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590	"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation"
XP_016986721.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016980508.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044317585.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_044313818.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_044312624.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016973268.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016989055.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016976179.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_016974447.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_016980938.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_044314417.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016978631.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_016989766.2	7	KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483148	"Glycerophospholipid metabolism";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PG"
XP_044313161.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044317198.1	26	Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-1234158;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568	"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase"
XP_016973379.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016985493.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016989552.2	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_016988275.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016975598.2	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis"
XP_044313855.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990538.2	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_016985355.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs"
XP_016982661.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016976668.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_016978534.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016990661.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016988541.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016978611.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016976406.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016982669.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016980499.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044317332.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044315122.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016987984.1	179	Reactome: R-HSA-450321;Reactome: R-HSA-8849469;Reactome: R-HSA-168638;Reactome: R-HSA-174113;Reactome: R-HSA-182971;Reactome: R-HSA-2691232;Reactome: R-HSA-4608870;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-937072;Reactome: R-HSA-5607761;Reactome: R-HSA-9033241;Reactome: R-HSA-8948747;Reactome: R-HSA-3322077;Reactome: R-HSA-382556;Reactome: R-HSA-3769402;Reactome: R-HSA-8854050;Reactome: R-HSA-5689901;Reactome: R-HSA-110320;Reactome: R-HSA-192823;Reactome: R-HSA-5656121;Reactome: R-HSA-975163;Reactome: R-HSA-68827;Reactome: R-HSA-901032;Reactome: R-HSA-450408;Reactome: R-HSA-2122947;Reactome: R-HSA-3134975;Reactome: R-HSA-110314;Reactome: R-HSA-180534;Reactome: R-HSA-917729;Reactome: R-HSA-174048;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-6782135;Reactome: R-HSA-2644606;Reactome: R-HSA-6804757;Reactome: R-HSA-9637628;Reactome: R-HSA-68949;Reactome: R-HSA-6782210;Reactome: R-HSA-1169091;Reactome: R-HSA-72706;Reactome: R-HSA-2173791;Reactome: R-HSA-400253;Reactome: R-HSA-1169408;Reactome: R-HSA-1253288;Reactome: R-HSA-2559585;Reactome: R-HSA-1358803;Reactome: R-HSA-975957;Reactome: R-HSA-9615710;Reactome: R-HSA-4641263;Reactome: R-HSA-2173795;Reactome: R-HSA-1236974;Reactome: R-HSA-6807004;Reactome: R-HSA-110312;Reactome: R-HSA-5689880;Reactome: R-HSA-2559580;Reactome: R-HSA-162588;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5696395;Reactome: R-HSA-2173796;Reactome: R-HSA-205043;Reactome: R-HSA-1236382;Reactome: R-HSA-174084;Reactome: R-HSA-5656169;Reactome: R-HSA-1234176;Reactome: R-HSA-2408557;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-532668;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-6804756;Reactome: R-HSA-9020702;Reactome: R-HSA-8856825;Reactome: R-HSA-8939236;Reactome: R-HSA-1799339;Reactome: R-HSA-6781823;Reactome: R-HSA-5689896;Reactome: R-HSA-9013973;Reactome: R-HSA-5654733;Reactome: R-HSA-6781827;Reactome: R-HSA-975110;Reactome: R-HSA-9010553;Reactome: R-HSA-209560;Reactome: R-HSA-5675482;Reactome: R-HSA-2894862;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-168927;Reactome: R-HSA-912631;Reactome: R-HSA-5205685;Reactome: R-HSA-9636383;Reactome: R-HSA-5654732;Reactome: R-HSA-8856828;Reactome: R-HSA-917937;Reactome: R-HSA-9645460;Reactome: R-HSA-5693565;Reactome: R-HSA-9013507;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-937039;Reactome: R-HSA-211733;Reactome: R-HSA-8863795;Reactome: R-HSA-5675221;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-1295596;Reactome: R-HSA-174490;Reactome: R-HSA-8876493;Reactome: R-HSA-156902;Reactome: R-HSA-5687128;Reactome: R-HSA-2122948;Reactome: R-HSA-5693607;Reactome: R-HSA-8866654;Reactome: R-HSA-5676590;Reactome: R-HSA-201681;Reactome: R-HSA-5668541;Reactome: R-HSA-209543;Reactome: R-HSA-5632684;Reactome: R-HSA-445989;Reactome: R-HSA-9633012;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5654726;Reactome: R-HSA-5654727;Reactome: R-HSA-450302;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-3785653;Reactome: R-HSA-5684264;Reactome: R-HSA-5658442;Reactome: R-HSA-9613829;Reactome: R-HSA-349425;Reactome: R-HSA-5696394;Reactome: R-HSA-6783310;Reactome: R-HSA-5357956;Reactome: R-HSA-975956;Reactome: R-HSA-937041;Reactome: R-HSA-69541;Reactome: R-HSA-2173788;Reactome: R-HSA-2979096;Reactome: R-HSA-9014325;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-156827;Reactome: R-HSA-5696397;Reactome: R-HSA-5678895;Reactome: R-HSA-936964;Reactome: R-HSA-5689877;Reactome: R-HSA-5362768;Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;Reactome: R-HSA-8875360;Reactome: R-HSA-72689;Reactome: R-HSA-8866652;Reactome: R-HSA-168928;Reactome: R-HSA-977225;Reactome: R-HSA-5696400;Reactome: R-HSA-5610785;Reactome: R-HSA-2672351;Reactome: R-HSA-187577;Reactome: R-HSA-937042;Reactome: R-HSA-936440;Reactome: R-HSA-9646399;Reactome: R-HSA-72764;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-5357905;Reactome: R-HSA-69231;Reactome: R-HSA-8852276;Reactome: R-HSA-6791226;Reactome: R-HSA-5655862;Reactome: R-HSA-175474;Reactome: R-HSA-69601;Reactome: R-HSA-975144	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"NOD1/2 Signaling Pathway";"SCF-beta-TrCP mediated degradation of Emi1";"EGFR downregulation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Asymmetric localization of PCP proteins";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Peroxisomal protein import";"Regulation of PTEN localization";"Glycogen synthesis";"ABC-family proteins mediated transport";"Deactivation of the beta-catenin transactivating complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Metalloprotease DUBs";"Translesion Synthesis by POLH";"Viral mRNA Translation";"Translesion synthesis by POLI";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CDT1 association with the CDC6:ORC:origin complex";"ER Quality Control Compartment (ERQC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of innate immune responses to cytosolic DNA";"Recognition of DNA damage by PCNA-containing replication complex";"Vpu mediated degradation of CD4";"Endosomal Sorting Complex Required For Transport (ESCRT)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Dual incision in TC-NER";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of TP53 Degradation";"Modulation by Mtb of host immune system";"Orc1 removal from chromatin";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of NF-kappaB in B cells";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Circadian Clock";"ISG15 antiviral mechanism";"Downregulation of ERBB4 signaling";"Oncogene Induced Senescence";"Downregulation of ERBB2:ERBB3 signaling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Late endosomal microautophagy";"Regulation of FZD by ubiquitination";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"ER-Phagosome pathway";"Negative regulation of MET activity";"Translesion synthesis by REV1";"Ub-specific processing proteases";"Oxidative Stress Induced Senescence";"Budding and maturation of HIV virion";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Formation of Incision Complex in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NRIF signals cell death from the nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Autodegradation of Cdh1 by Cdh1:APC/C";"Termination of translesion DNA synthesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Selenocysteine synthesis";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neddylation";"UCH proteinases";"Regulation of TP53 Activity through Phosphorylation";"Interleukin-1 signaling";"Cargo recognition for clathrin-mediated endocytosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of TC-NER Pre-Incision Complex";"Ovarian tumor domain proteases";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulation of FGFR4 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of expression of SLITs and ROBOs";"NF-kB is activated and signals survival";"Regulation of necroptotic cell death";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of signaling by CBL";"Pink/Parkin Mediated Mitophagy";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of FGFR3 signaling";"Clathrin-mediated endocytosis";"Iron uptake and transport";"Alpha-protein kinase 1 signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Downstream TCR signaling";"Degradation of DVL";"IRAK1 recruits IKK complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downregulation of ERBB2 signaling";"Negative regulation of MAPK pathway";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Spry regulation of FGF signaling";"Membrane binding and targetting of GAG proteins";"InlA-mediated entry of Listeria monocytogenes into host cells";"Peptide chain elongation";"MAPK6/MAPK4 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Processing of DNA double-strand break ends";"E3 ubiquitin ligases ubiquitinate target proteins";"NIK-->noncanonical NF-kB signaling";"TCF dependent signaling in response to WNT";"TNFR2 non-canonical NF-kB pathway";"p75NTR recruits signalling complexes";"Hedgehog 'on' state";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR2 signaling";"activated TAK1 mediates p38 MAPK activation";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Myoclonic epilepsy of Lafora";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RAS by GAPs";"Chaperone Mediated Autophagy";"Autodegradation of the E3 ubiquitin ligase COP1";"DNA Damage Recognition in GG-NER";"Fanconi Anemia Pathway";"TNFR1-induced NFkappaB signaling pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"IKK complex recruitment mediated by RIP1";"Stabilization of p53";"Downregulation of TGF-beta receptor signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"L13a-mediated translational silencing of Ceruloplasmin expression";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Defective CFTR causes cystic fibrosis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Josephin domain DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Formation of a pool of free 40S subunits";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amyloid fiber formation";"Dual Incision in GG-NER";"GLI3 is processed to GLI3R by the proteasome";"Stimuli-sensing channels";"SCF(Skp2)-mediated degradation of p27/p21";"IRAK2 mediated activation of TAK1 complex";"Negative regulators of DDX58/IFIH1 signaling";"Aggrephagy";"Eukaryotic Translation Termination";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of TNFR1 signaling";"Cyclin D associated events in G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translesion synthesis by POLK";"Assembly Of The HIV Virion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_016982380.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_044317721.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_016983400.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016972606.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016989637.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-171007	"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"p38MAPK events"
XP_016972599.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_044317384.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016977563.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_044316726.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016979472.1	4	Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_016979632.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_016980257.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_016981773.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016979114.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_044313510.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016987583.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016976284.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6433	"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_044313512.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016972623.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016978905.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044316259.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044312608.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-5689877	"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Amyloid fiber formation";"Josephin domain DUBs"
XP_016980820.2	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016981775.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044316079.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016987577.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016982780.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016983959.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_016984327.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_016984816.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016984722.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016990212.1	18	Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788	"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC"
XP_016978995.2	17	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1	"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Human papillomavirus infection";"Meiotic synapsis";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Relaxin signaling pathway"
XP_016988782.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044316579.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016970327.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_016975116.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016990227.1	24	Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-392451	"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma"
XP_016983523.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016987747.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_016983308.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016981465.2	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016972383.1	52	Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-8851708;Reactome: R-HSA-5578749;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-5617472;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-76066	"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"mRNA Capping";"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM";"Transcriptional regulation by small RNAs";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_016976542.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016971488.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044315811.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016982750.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016970845.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360	"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_016983926.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016972070.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044315439.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016982281.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016984469.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016986706.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016979764.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_016981805.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016989980.2	13	MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-7909;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3	"L-histidine degradation III";"One carbon pool by folate";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes"
XP_016985551.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044316539.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling"
XP_016989099.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_016988805.2	9	MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12	"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis"
XP_016991833.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_044314414.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016970825.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016986711.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044313120.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016988389.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016971895.1	4	Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642	"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation"
XP_016981810.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016978317.2	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation"
XP_016989875.2	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016977958.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016984992.2	29	Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167162	"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape"
XP_016980812.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016970281.1	9	MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94	"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism"
XP_044313455.1	30	Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-2122947;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-2644606;Reactome: R-HSA-68949;Reactome: R-HSA-917937;Reactome: R-HSA-2644607;Reactome: R-HSA-5676590	"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Prolactin receptor signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Circadian Clock";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Orc1 removal from chromatin";"Iron uptake and transport";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"NIK-->noncanonical NF-kB signaling"
XP_016988813.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_044315676.1	17	Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-1433557;Reactome: R-HSA-5693607	"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"Transcriptional Regulation by E2F6";"Signaling by SCF-KIT";"Processing of DNA double-strand break ends"
XP_016970802.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_044317342.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016984986.2	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling"
XP_016978833.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_044315680.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016973678.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_016977122.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044312803.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_016980248.1	7	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2	"Mitochondrial protein import";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation"
XP_016973508.1	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016973146.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016972276.2	10	Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-983231	"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production"
XP_016980305.2	3	KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"Glycine degradation";"One carbon pool by folate"
XP_016985452.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016991905.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway"
XP_016990063.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_016991222.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_044316466.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016986984.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_044312723.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016982201.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016977984.1	3	Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism"
XP_016971285.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_044314188.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_016984639.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_044315071.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016986584.2	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_016969468.1	18	MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1	"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis"
XP_016973024.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_016987136.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_016981629.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016981811.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016973900.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
XP_016975703.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895	"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism"
XP_016973776.1	8	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_016986994.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044316791.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016978456.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016976721.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016981952.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_016989951.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616	"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_016973978.1	9	MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-196780	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism"
XP_044314831.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016979606.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044315543.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016984411.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway"
XP_016978904.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016970623.2	4	MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism"
XP_016986839.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_016987829.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016979820.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_044312929.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044312548.1	3	Reactome: R-HSA-201722;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"HATs acetylate histones"
XP_044316125.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016988826.2	6	MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_016971773.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_016987628.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044317111.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_044312780.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016969514.2	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_016974412.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_016973006.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016973991.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_016979842.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_016976283.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_016977776.2	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016980506.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016974019.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016991635.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_044315434.1	42	Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-73728;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-212300;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858	"DNA methylation";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Opening";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Packaging Of Telomere Ends";"Meiotic synapsis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged purine";"Meiotic recombination";"Amyloid fiber formation";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"PRC2 methylates histones and DNA";"HCMV Late Events";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines"
XP_044317006.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168333	"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_016987366.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016979415.2	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy"
XP_016983117.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_016971408.2	6	Reactome: R-HSA-70221;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-6731;MetaCyc: PWY-7238	"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation III";"Sucrose biosynthesis II"
XP_016984445.2	8	Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_016975953.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016991488.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016970025.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_016991946.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016991498.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016969676.2	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation"
XP_016984636.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_016986044.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044313123.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016983851.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016978079.2	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_016991056.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016977128.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016974323.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_044313946.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Ub-specific processing proteases";"Regulation of PTEN stability and activity"
XP_016974559.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016986723.1	9	KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533	"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Gliotoxin biosynthesis"
XP_016980071.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684	"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state"
XP_016985316.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_016975377.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016982731.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_044313254.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_044312811.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016969941.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_016990044.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016989947.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016980722.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2	"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"T cell receptor signaling pathway"
XP_016983389.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016987929.1	4	KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193	"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016986729.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016984419.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_016985836.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_016981354.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_016976507.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_016982445.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_016987429.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_016982301.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016973460.2	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_044313750.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_016977327.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016984242.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016973063.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_044314023.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016980674.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016970176.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-159227	"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA"
XP_016989046.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_016972468.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_016983745.2	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_016985624.1	9	KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204	"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_016980016.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016986224.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_016986875.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016982433.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044314955.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_016981401.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane"
XP_016978952.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016972503.2	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_016985711.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016990721.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016980172.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016976854.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016991578.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044314725.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044317257.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016986173.1	7	Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897	"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes"
XP_044312902.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016987084.2	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_044312585.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016977158.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_044313546.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016975259.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016987526.2	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_016985053.2	1	Reactome: R-HSA-419771	"Opsins"
XP_016979410.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897	"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes"
XP_016974270.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_016986961.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016989555.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_044313139.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7725	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_016984026.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016980940.2	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_016980433.2	7	MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25	"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Streptomycin biosynthesis"
XP_044314952.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_016992307.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_016979928.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044317258.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016987736.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
XP_016990925.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016969325.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044314321.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016971291.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016980583.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016979714.1	5	Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2"
XP_016973812.2	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_016972624.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016983204.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_016977688.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016969071.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016972417.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_016985388.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_044314648.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016973802.2	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_016989437.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016986720.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016969188.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016969584.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_016992115.2	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_044316844.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016989095.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation"
XP_016981796.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016987026.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044313356.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016972799.2	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_044317367.1	6	KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_016990938.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016974809.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016981343.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044314570.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_016978301.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016985024.2	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044312416.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016991322.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_044314772.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_016985026.2	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_016982102.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_016983786.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044315098.1	22	Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340	"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex"
XP_016984320.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_016977098.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044313940.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Protein ubiquitination";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_016988163.2	6	MetaCyc: PWY-6368;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
XP_016969737.1	8	MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;Reactome: R-HSA-6798695	"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Purine metabolism";"Surfactant metabolism";"Purine salvage";"Neutrophil degranulation"
XP_016987605.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_016987229.2	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_016974791.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016975976.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_016979255.2	10	Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483	"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs"
XP_016984632.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_044312545.1	10	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722	"Human cytomegalovirus infection";"Relaxin signaling pathway";"HATs acetylate histones";"Ub-specific processing proteases";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex"
XP_016970048.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_016987649.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044313579.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016973173.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016975460.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016986710.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016989309.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_016968981.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016974565.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_016974910.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_016980435.1	7	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Phytate degradation I"
XP_044316576.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016976611.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016975654.1	4	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_016989582.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_016992135.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016983972.1	6	MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11	"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism"
XP_016975671.2	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016980835.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016971843.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_016982192.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044316339.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016978769.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones"
XP_044317926.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016991584.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
XP_016992188.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"Heme biosynthesis"
XP_044314334.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016990904.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016984752.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016980813.1	7	Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690	"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"HCMV Early Events"
XP_016983264.2	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_016990653.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016984412.1	10	MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-6842	"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II"
XP_044312417.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016979364.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
XP_044313604.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979127.2	7	Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_016979339.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044315987.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016981814.2	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_016973156.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016992016.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_016969322.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044315005.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_016969176.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_016980967.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016988420.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772	"Signaling by Leptin";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling"
XP_016985205.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016982726.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016974361.2	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044313810.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016982905.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_016987852.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016968985.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016990646.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016978442.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_044314018.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_016982444.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_016979801.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016974898.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016987510.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016989021.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016978360.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016990964.1	83	Reactome: R-HSA-5655253;Reactome: R-HSA-1433559;Reactome: R-HSA-9027284;Reactome: R-HSA-8865999;Reactome: R-HSA-5654689;Reactome: R-HSA-210993;Reactome: R-HSA-8875360;Reactome: R-HSA-2029482;Reactome: R-HSA-74751;Reactome: R-HSA-109704;Reactome: R-HSA-2428933;Reactome: R-HSA-5654733;Reactome: R-HSA-5654710;Reactome: R-HSA-1963642;Reactome: R-HSA-5654720;Reactome: R-HSA-1257604;Reactome: R-HSA-983695;Reactome: R-HSA-2871796;Reactome: R-HSA-512988;Reactome: R-HSA-1250196;Reactome: R-HSA-8983432;Reactome: R-HSA-8856825;Reactome: R-HSA-9607240;Reactome: R-HSA-8875555;Reactome: R-HSA-389359;Reactome: R-HSA-167044;Reactome: R-HSA-2219530;Reactome: R-HSA-5654700;Reactome: R-HSA-9034864;Reactome: R-HSA-5654699;Reactome: R-HSA-5654727;Reactome: R-HSA-375165;Reactome: R-HSA-179812;Reactome: R-HSA-8851805;Reactome: R-HSA-5654719;Reactome: R-HSA-74749;Reactome: R-HSA-112412;Reactome: R-HSA-1236382;Reactome: R-HSA-912526;Reactome: R-HSA-5655291;Reactome: R-HSA-9028335;Reactome: R-HSA-6807004;Reactome: R-HSA-5654704;Reactome: R-HSA-9634285;Reactome: R-HSA-9664565;Reactome: R-HSA-5654695;Reactome: R-HSA-1295596;Reactome: R-HSA-5654706;Reactome: R-HSA-1839117;Reactome: R-HSA-1963640;Reactome: R-HSA-8853659;Reactome: R-HSA-5654693;Reactome: R-HSA-5655302;Reactome: R-HSA-2871809;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-8853334;Reactome: R-HSA-5637810;Reactome: R-HSA-5654726;Reactome: R-HSA-391160;Reactome: R-HSA-8851907;Reactome: R-HSA-8853338;Reactome: R-HSA-1433557;Reactome: R-HSA-9028731;Reactome: R-HSA-912631;Reactome: R-HSA-2179392;Reactome: R-HSA-180292;Reactome: R-HSA-9645135;Reactome: R-HSA-5673001;Reactome: R-HSA-354194;Reactome: R-HSA-186763;Reactome: R-HSA-182971;Reactome: R-HSA-8875656;Reactome: R-HSA-5654688;Reactome: R-HSA-5654712;Reactome: R-HSA-5654732;Reactome: R-HSA-1250347;Reactome: R-HSA-2424491;Reactome: R-HSA-180336;Reactome: R-HSA-8856828;Reactome: R-HSA-9026519;Reactome: R-HSA-5663213;Reactome: R-HSA-2730905	"Signaling by FGFR2 in disease";"Regulation of KIT signaling";"Erythropoietin activates RAS";"MET activates PTPN11";"PI-3K cascade:FGFR1";"Tie2 Signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of actin dynamics for phagocytic cup formation";"Insulin receptor signalling cascade";"PI3K Cascade";"SHC-related events triggered by IGF1R";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR3";"PI3K events in ERBB2 signaling";"PI-3K cascade:FGFR4";"PIP3 activates AKT signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated MAPK activation";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB2 signaling";"Interleukin-15 signaling";"Cargo recognition for clathrin-mediated endocytosis";"FLT3 Signaling";"MET activates RAP1 and RAC1";"CD28 dependent Vav1 pathway";"Signalling to RAS";"Constitutive Signaling by Aberrant PI3K in Cancer";"FRS-mediated FGFR2 signaling";"Activated NTRK3 signals through RAS";"SHC-mediated cascade:FGFR2";"Negative regulation of FGFR2 signaling";"NCAM signaling for neurite out-growth";"GRB2 events in EGFR signaling";"MET activates RAS signaling";"SHC-mediated cascade:FGFR4";"Signal attenuation";"SOS-mediated signalling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Interleukin receptor SHC signaling";"Signaling by FGFR4 in disease";"Activated NTRK2 signals through PI3K";"Negative regulation of MET activity";"SHC-mediated cascade:FGFR3";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2 KD Mutants";"PI-3K cascade:FGFR2";"Spry regulation of FGF signaling";"FRS-mediated FGFR3 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"GRB2 events in ERBB2 signaling";"RET signaling";"FRS-mediated FGFR1 signaling";"Signaling by FGFR1 in disease";"FCERI mediated Ca+2 mobilization";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by EGFRvIII";"Negative regulation of FGFR1 signaling";"Signal regulatory protein family interactions";"MET activates PI3K/AKT signaling";"Signaling by FGFR3 point mutants in cancer";"Signaling by SCF-KIT";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of signaling by CBL";"EGFR Transactivation by Gastrin";"GAB1 signalosome";"STAT5 Activation";"RAF/MAP kinase cascade";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Downstream signal transduction";"EGFR downregulation";"MET receptor recycling";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR4 signaling";"Negative regulation of FGFR3 signaling";"SHC1 events in ERBB4 signaling";"DAP12 signaling";"SHC1 events in EGFR signaling";"Clathrin-mediated endocytosis";"Activated NTRK2 signals through RAS";"RHO GTPases Activate WASPs and WAVEs";"Role of LAT2/NTAL/LAB on calcium mobilization"
XP_016987387.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044316882.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016980591.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016981467.2	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016985727.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016969063.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016973755.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_016970774.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016981939.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016973498.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_016987676.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_016977755.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016980182.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948	"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Signaling downstream of RAS mutants"
XP_044314155.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016990193.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016981965.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016981578.1	18	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_016979126.2	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016986177.1	7	KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897	"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes"
XP_016976603.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_044317554.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016968966.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016987164.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_016985279.1	20	KEGG: 00720+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-5172;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;Reactome: R-HSA-1268020;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5	"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Mitochondrial protein import";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism"
XP_016983087.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016982761.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_016972427.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016987166.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_044315576.1	5	Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108	"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_044314767.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016977856.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_016982899.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016976539.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016990965.1	83	Reactome: R-HSA-8865999;Reactome: R-HSA-210993;Reactome: R-HSA-5654689;Reactome: R-HSA-109704;Reactome: R-HSA-74751;Reactome: R-HSA-8875360;Reactome: R-HSA-2029482;Reactome: R-HSA-2428933;Reactome: R-HSA-5655253;Reactome: R-HSA-1433559;Reactome: R-HSA-9027284;Reactome: R-HSA-1250196;Reactome: R-HSA-8983432;Reactome: R-HSA-8856825;Reactome: R-HSA-9607240;Reactome: R-HSA-389359;Reactome: R-HSA-8875555;Reactome: R-HSA-5654733;Reactome: R-HSA-1963642;Reactome: R-HSA-5654710;Reactome: R-HSA-5654720;Reactome: R-HSA-983695;Reactome: R-HSA-1257604;Reactome: R-HSA-2871796;Reactome: R-HSA-512988;Reactome: R-HSA-9034864;Reactome: R-HSA-5654699;Reactome: R-HSA-375165;Reactome: R-HSA-5654727;Reactome: R-HSA-2219530;Reactome: R-HSA-167044;Reactome: R-HSA-5654700;Reactome: R-HSA-6807004;Reactome: R-HSA-912526;Reactome: R-HSA-5655291;Reactome: R-HSA-9028335;Reactome: R-HSA-5654704;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-5654719;Reactome: R-HSA-8851805;Reactome: R-HSA-179812;Reactome: R-HSA-112412;Reactome: R-HSA-74749;Reactome: R-HSA-1236382;Reactome: R-HSA-8853659;Reactome: R-HSA-5655302;Reactome: R-HSA-5654693;Reactome: R-HSA-388841;Reactome: R-HSA-2871809;Reactome: R-HSA-6811558;Reactome: R-HSA-5654695;Reactome: R-HSA-1839117;Reactome: R-HSA-5654706;Reactome: R-HSA-1295596;Reactome: R-HSA-1963640;Reactome: R-HSA-391160;Reactome: R-HSA-8851907;Reactome: R-HSA-1433557;Reactome: R-HSA-8853338;Reactome: R-HSA-8853334;Reactome: R-HSA-5654726;Reactome: R-HSA-5637810;Reactome: R-HSA-180292;Reactome: R-HSA-5673001;Reactome: R-HSA-9645135;Reactome: R-HSA-186763;Reactome: R-HSA-354194;Reactome: R-HSA-182971;Reactome: R-HSA-912631;Reactome: R-HSA-9028731;Reactome: R-HSA-2179392;Reactome: R-HSA-2424491;Reactome: R-HSA-5654732;Reactome: R-HSA-1250347;Reactome: R-HSA-9026519;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-180336;Reactome: R-HSA-2730905;Reactome: R-HSA-8875656;Reactome: R-HSA-5654712;Reactome: R-HSA-5654688	"MET activates PTPN11";"Tie2 Signaling";"PI-3K cascade:FGFR1";"PI3K Cascade";"Insulin receptor signalling cascade";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of actin dynamics for phagocytic cup formation";"SHC-related events triggered by IGF1R";"Signaling by FGFR2 in disease";"Regulation of KIT signaling";"Erythropoietin activates RAS";"SHC1 events in ERBB2 signaling";"Interleukin-15 signaling";"Cargo recognition for clathrin-mediated endocytosis";"FLT3 Signaling";"CD28 dependent Vav1 pathway";"MET activates RAP1 and RAC1";"Negative regulation of FGFR4 signaling";"PI3K events in ERBB2 signaling";"PI-3K cascade:FGFR3";"PI-3K cascade:FGFR4";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PIP3 activates AKT signaling";"FCERI mediated MAPK activation";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Activated NTRK3 signals through RAS";"SHC-mediated cascade:FGFR2";"NCAM signaling for neurite out-growth";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signalling to RAS";"FRS-mediated FGFR2 signaling";"Negative regulation of MET activity";"Interleukin receptor SHC signaling";"Signaling by FGFR4 in disease";"Activated NTRK2 signals through PI3K";"SHC-mediated cascade:FGFR3";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"SHC-mediated cascade:FGFR4";"MET activates RAS signaling";"GRB2 events in EGFR signaling";"SOS-mediated signalling";"Signal attenuation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"RET signaling";"Signaling by FGFR1 in disease";"FRS-mediated FGFR1 signaling";"Costimulation by the CD28 family";"FCERI mediated Ca+2 mobilization";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI-3K cascade:FGFR2";"Signaling by cytosolic FGFR1 fusion mutants";"FRS-mediated FGFR3 signaling";"Spry regulation of FGF signaling";"GRB2 events in ERBB2 signaling";"Signal regulatory protein family interactions";"MET activates PI3K/AKT signaling";"Signaling by SCF-KIT";"Signaling by FGFR3 point mutants in cancer";"Signaling by FGFR3 fusions in cancer";"Negative regulation of FGFR1 signaling";"Constitutive Signaling by EGFRvIII";"GAB1 signalosome";"RAF/MAP kinase cascade";"STAT5 Activation";"Downstream signal transduction";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"EGFR downregulation";"Regulation of signaling by CBL";"Activated NTRK2 signals through FRS2 and FRS3";"EGFR Transactivation by Gastrin";"DAP12 signaling";"Negative regulation of FGFR3 signaling";"SHC1 events in ERBB4 signaling";"Activated NTRK2 signals through RAS";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"SHC1 events in EGFR signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"MET receptor recycling";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR1"
XP_044313683.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016987135.1	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-7282	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_016980425.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016978371.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016974012.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016973750.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016979577.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016988399.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_016984467.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142	"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Late Events";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins"
XP_016985176.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_044316702.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_044315475.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016989497.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_016991787.2	5	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_016987161.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_016989115.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016981934.1	4	MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450	"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_044316793.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016987817.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_016976402.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_016982012.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_016974775.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_016980957.2	5	MetaCyc: PWY-7185;MetaCyc: PWY-7176;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943	"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_044313345.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016980426.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044316520.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_044316526.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_016972998.2	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016986912.2	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016987639.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_044312659.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events"
XP_016987859.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_044312845.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_016976613.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_016970697.1	3	Reactome: R-HSA-6807505;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016979246.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016986758.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044315314.1	44	Reactome: R-HSA-2871796;Reactome: R-HSA-6802946;Reactome: R-HSA-198753;Reactome: R-HSA-450341;Reactome: R-HSA-5654726;Reactome: R-HSA-112409;Reactome: R-HSA-445144;Reactome: R-HSA-5654733;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-879415;Reactome: R-HSA-162658;Reactome: R-HSA-1295596;Reactome: R-HSA-5675221;Reactome: R-HSA-2029482;Reactome: R-HSA-202670;Reactome: R-HSA-6802948;Reactome: R-HSA-6811558;Reactome: R-HSA-456926;Reactome: R-HSA-9627069;Reactome: R-HSA-9634638;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.24;Reactome: R-HSA-74749;Reactome: R-HSA-8940973;Reactome: R-HSA-6802955;Reactome: R-HSA-982772;Reactome: R-HSA-881907;Reactome: R-HSA-5674499;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-5654732;Reactome: R-HSA-6802952;Reactome: R-HSA-5663213;Reactome: R-HSA-5668599;Reactome: R-HSA-170968;Reactome: R-HSA-9635465;Reactome: R-HSA-2559582;Reactome: R-HSA-444257;Reactome: R-HSA-8939211;Reactome: R-HSA-375165;Reactome: R-HSA-5654727;Reactome: R-HSA-2559585;Reactome: R-HSA-5673001	"FCERI mediated MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"ERK/MAPK targets";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR1 signaling";"RAF-independent MAPK1/3 activation";"Signal transduction by L1";"Negative regulation of FGFR4 signaling";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Advanced glycosylation endproduct receptor signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Spry regulation of FGF signaling";"Negative regulation of MAPK pathway";"Regulation of actin dynamics for phagocytic cup formation";"ERKs are inactivated";"Signaling by high-kinase activity BRAF mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Regulation of the apoptosome activity";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Signal attenuation";"RUNX2 regulates osteoblast differentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Growth hormone receptor signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative feedback regulation of MAPK pathway";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Negative regulation of FGFR3 signaling";"Signaling by BRAF and RAF fusions";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate NADPH Oxidases";"Frs2-mediated activation";"Suppression of apoptosis";"Senescence-Associated Secretory Phenotype (SASP)";"RSK activation";"ESR-mediated signaling";"NCAM signaling for neurite out-growth";"Negative regulation of FGFR2 signaling";"Oncogene Induced Senescence";"RAF/MAP kinase cascade"
XP_016974608.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016981803.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016984717.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044317825.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23	"Neutrophil degranulation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation"
XP_044314936.1	29	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-69541;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;Reactome: R-HSA-6803207;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-349425;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Stabilization of p53";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"PI3K-Akt signaling pathway";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway"
XP_044312766.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016970215.2	14	MetaCyc: PWY-8051;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4	"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PC";"Anandamide biosynthesis II";"Ether lipid metabolism"
XP_016983387.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044316788.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016987819.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016975112.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_044313700.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway"
XP_044314120.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_016981996.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016979782.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_044314720.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016981955.2	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_016981876.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_016981768.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_016989753.1	23	Reactome: R-HSA-420092;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-392851	"Glucagon-type ligand receptors";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G alpha (z) signalling events";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor"
XP_044314171.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016972224.1	42	KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7401;MetaCyc: PWY-5789;MetaCyc: PWY-6944;MetaCyc: PWY-6435;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-6863;MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7779;KEGG: 00903+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00592+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7216;MetaCyc: PWY-1361;MetaCyc: PWY-5177;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-7726;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7007	"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Androstenedione degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation";"beta-Alanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"Methyl tert-butyl ether degradation";"Limonene and pinene degradation";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Fatty acid salvage";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Butanoate metabolism";"Fatty acid degradation";"Benzoate degradation";"Fermentation to 2-methylbutanoate";"alpha-Linolenic acid metabolism";"Toluene degradation";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"2-methylpropene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Glutaryl-coa degradation";"Propanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Caprolactam degradation";"Geraniol degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Methyl ketone biosynthesis (engineered)"
XP_016976432.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_044315863.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044314143.1	11	Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"HS-GAG biosynthesis"
XP_044316884.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016977925.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016990870.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_044315360.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044313756.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044313170.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044315851.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016989079.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_016973796.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_044317354.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events"
XP_016988165.2	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_016987224.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
XP_016975168.2	13	Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-450321	"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_016971274.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_016969946.1	10	KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174	"Butanoate metabolism";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)"
XP_016990275.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016989051.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_016988105.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016988692.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803;Reactome: R-HSA-2151201;MetaCyc: PWY-6854	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)"
XP_016970820.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761	"Downstream TCR signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_016990123.1	7	KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16	"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_016974461.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016988099.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_016990357.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016991632.2	9	Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68952	"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"DNA replication initiation"
XP_044313932.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016986154.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-168333	"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_016990909.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016976602.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_044317361.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016985413.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_016982099.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones"
XP_016971878.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_044317056.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_016986042.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016989061.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-177929	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Signaling by EGFR"
XP_016980221.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_016977950.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044314186.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_016973631.1	13	Reactome: R-HSA-532668;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-6798695;Reactome: R-HSA-110320;Reactome: R-HSA-3371511;Reactome: R-HSA-8876725;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-8866654	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"Neutrophil degranulation";"Translesion Synthesis by POLH";"HSF1 activation";"Protein methylation";"Josephin domain DUBs";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016978058.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044314851.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016991996.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_016982872.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016975996.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016988075.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016969832.2	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_044316876.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044312910.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016982460.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016973260.1	8	MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5740;Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5739	"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis";"GDP-D-perosamine biosynthesis"
XP_044316080.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016977555.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979363.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_044313792.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_016976389.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044313668.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016988281.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016974756.1	11	MetaCyc: PWY-5381;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-5695	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation"
XP_016979352.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016985457.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016977902.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016985096.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016970590.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_044317329.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_044314112.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_016982289.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_016989181.1	37	Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-204005;Reactome: R-HSA-5578749;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-9639288;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-983170;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107	"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"COPII-mediated vesicle transport";"Transcriptional regulation by small RNAs";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Amino acids regulate mTORC1";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_016989754.1	23	Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (i) signalling events"
XP_016988184.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-68877	"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Kinesins";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Gap junction assembly";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"Mitotic Prometaphase"
XP_016980715.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_016968963.1	3	MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12	"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_016991763.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-68884	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Telophase/Cytokinesis"
XP_044314084.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_016978970.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_044316535.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_044312817.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_044312796.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_016970819.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016973122.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_044315908.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_016988652.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016988039.2	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016992187.1	17	Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174084	"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_044312400.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016972428.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016973285.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016977935.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016976184.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_016977842.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016989551.2	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_016971076.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016981769.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016977356.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_016985500.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016984623.2	4	MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping"
XP_016985723.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044313331.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016990566.2	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016976564.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044313341.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_016972082.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_016980344.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016978549.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016984780.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016975071.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016992055.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044315691.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016983276.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016984898.1	4	MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20	"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism"
XP_016991507.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016982275.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_016973744.1	8	MetaCyc: PWY-7817;KEGG: 04660+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5269;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16	"Type I lipoteichoic acid biosynthesis (S. aureus)";"T cell receptor signaling pathway";"Synthesis of PG";"Cardiolipin biosynthesis II";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044313537.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016991164.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016991370.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016986045.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016971487.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044315768.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_016987237.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016977130.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016978622.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016979420.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016974722.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016969061.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_044317095.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016982621.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016987232.2	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_044315432.1	42	Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-73728;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690	"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Estrogen-dependent gene expression";"DNA methylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"Meiotic synapsis";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation";"Cleavage of the damaged purine";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"HCMV Late Events";"PRC2 methylates histones and DNA";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events"
XP_016971903.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_016972713.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_016984365.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016987023.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_016974090.2	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_016973801.2	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_044317822.1	10	KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695	"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"HS-GAG degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation"
XP_044315510.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016973924.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044314785.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016978502.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_016983737.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_016972421.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016970021.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016980179.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER"
XP_044314172.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016987861.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016974488.2	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_016978485.2	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_044313118.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016980079.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_016977794.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_016969628.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_044315986.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016977859.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016978651.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016982452.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016968986.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044312842.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_016981510.1	4	Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281	"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_016986565.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_016973931.1	30	Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-2644607;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-2644606;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69231	"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Prolactin receptor signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Iron uptake and transport";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1"
XP_044314915.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016969485.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_016984604.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016985992.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_016979799.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_016968862.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016977470.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016977619.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016981922.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016980264.2	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016979186.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_016989102.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016981036.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016985448.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016974122.2	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_016984634.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_016972321.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016978533.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016976140.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016976793.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Macroautophagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016982400.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016981161.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016990128.1	5	Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-6798695	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation"
XP_016977490.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_016977832.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_016982724.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_016973414.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016984247.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016977026.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016981910.2	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Degradation of the extracellular matrix"
XP_016989578.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_016976849.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016985502.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016981926.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016972740.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016984654.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_044317563.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016989733.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_016987073.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_016988397.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044313578.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016987934.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_016984630.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016983512.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_016973416.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_016981027.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016979241.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044315008.1	5	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation"
XP_016980935.2	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_044314638.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016980822.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044315064.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016972249.1	11	MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4	"Anandamide biosynthesis I";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Role of phospholipids in phagocytosis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism"
XP_016990268.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113	"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1"
XP_016972576.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751	"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Neutrophil degranulation";"WNT mediated activation of DVL";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity"
XP_016981425.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016973859.1	6	Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_044314090.1	11	Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096	"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation"
XP_016979759.1	29	Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-6781823	"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex"
XP_016969238.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044312827.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_044315483.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016986243.2	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_044317961.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_044316181.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_044314951.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016969523.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016973966.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016978122.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016984498.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016985557.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_016973664.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016989550.2	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism"
XP_016983770.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_044315285.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016975326.2	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_016992184.2	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism"
XP_016982866.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_016992303.2	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_016974721.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_016972246.1	7	MetaCyc: PWY-6352;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499;MetaCyc: PWY-6351;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67	"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism"
XP_016976604.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016985415.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_016979575.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016979567.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol"
XP_016977015.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_016986772.1	17	Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-9645460;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-202424;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-937042;Reactome: R-HSA-937072	"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"Ub-specific processing proteases";"Alpha-protein kinase 1 signaling pathway";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_016981772.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016980593.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044313975.1	26	Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082	"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression"
XP_044317931.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016971206.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_016990051.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016978946.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_044313097.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211945	"PPARA activates gene expression";"Endogenous sterols";"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds"
XP_044316800.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016969333.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016986605.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044314647.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044313577.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016969376.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_016992125.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016989323.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_044317259.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_044315357.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016989186.2	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016975672.2	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016979268.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_016982970.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979692.1	8	KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;Reactome: R-HSA-5683826	"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine salvage";"Surfactant metabolism"
XP_044312660.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_016981942.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016986569.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_044316784.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016987022.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044314331.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_044316092.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_044317271.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016983425.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-373080;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263	"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins";"Ca2+ pathway";"Class B/2 (Secretin family receptors)";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination"
XP_016975682.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339	"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_016988241.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway"
XP_016980354.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016980795.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_016970244.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_016970335.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016972705.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-75955	"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation"
XP_016976057.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_016969221.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016975574.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016990727.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016979035.2	2	Reactome: R-HSA-202733;Reactome: R-HSA-140875	"Cell surface interactions at the vascular wall";"Common Pathway of Fibrin Clot Formation"
XP_016990260.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982832.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016980909.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016978329.1	5	KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_016983516.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877	"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase"
XP_016991366.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979406.2	3	Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_016982293.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016972964.1	4	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016990169.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_016979780.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_016990871.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016978569.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity"
XP_044312407.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044314019.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_016969750.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016985281.1	20	KEGG: 00720+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;MetaCyc: PWY-5690;MetaCyc: PWY-5538;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;Reactome: R-HSA-75105;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5	"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Mitochondrial protein import";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism"
XP_044313511.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016974671.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016989692.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_016972834.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016982910.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016978535.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016971642.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016982161.1	15	Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-5689896	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Ovarian tumor domain proteases"
XP_016974558.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016970050.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016985320.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_044313671.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_016986884.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044317410.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_016969414.2	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_016978003.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport"
XP_016983938.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016975120.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016974357.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin"
XP_016979667.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016974794.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016982303.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016986930.2	10	Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_016982893.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016973877.1	11	MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9	"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism"
XP_016973959.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016979175.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016990237.2	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_016989767.2	7	KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483148	"Glycerophospholipid metabolism";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PG"
XP_044314422.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016969411.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044316009.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982834.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_016971936.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016984731.1	8	Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_044317089.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016988276.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977319.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016979852.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1"
XP_016978676.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016981212.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016988175.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016979289.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_044314886.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016988986.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016974347.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_016979442.2	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016982906.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016981469.2	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016984074.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_016970971.1	7	Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_016970491.1	11	MetaCyc: PWY-5123;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6859;MetaCyc: PWY-922;MetaCyc: PWY-7102;MetaCyc: PWY-6174;MetaCyc: PWY-6383;MetaCyc: PWY-7560	"Trans, trans-farnesyl diphosphate biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Mevalonate pathway I";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway II (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II"
XP_044315044.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_044313827.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016980112.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-69473	"Estrogen-dependent gene expression";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint"
XP_044316897.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016982619.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016980084.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_044315422.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016977806.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016989999.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_044312839.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_016973281.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_044317082.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016979079.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_016978600.1	20	MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-6920;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7858	"Jasmonic acid biosynthesis";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II"
XP_016972199.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_016991250.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_016973754.2	57	Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974	"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway"
XP_016984197.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016972248.1	11	KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-2029485;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051	"Ether lipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Role of phospholipids in phagocytosis";"Sphingolipid metabolism";"Anandamide biosynthesis I"
XP_016981812.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016981720.2	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_044316875.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044317550.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_016971140.1	8	Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690	"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"Regulation of PTEN gene transcription";"HCMV Early Events"
XP_016980070.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016984754.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016983105.2	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_016986185.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_016969330.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016988419.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231	"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_016977115.1	10	Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5368286;KEGG: 00020+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Mitochondrial translation initiation";"Citrate cycle (TCA cycle)"
XP_016990550.2	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016989909.1	8	Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_044317092.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase"
XP_016975601.2	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016976837.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044315880.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_016988102.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_044313945.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_016991479.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_016984799.2	5	Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-209560	"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival"
XP_044315750.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_016972625.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016989027.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044317925.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016973671.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_044312836.1	31	MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-5994;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;MetaCyc: PWY-7723;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-8049;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWY-5989;MetaCyc: PWY-5142;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-6282;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-8047;MetaCyc: PWY-5147	"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Pederin biosynthesis";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)"
XP_016991260.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016990862.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016970700.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016971277.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016984010.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_016989722.1	22	MetaCyc: PWY-622;MetaCyc: PWY-5384;Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;KEGG: 00030+5.3.1.9;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5054;Reactome: R-HSA-70171;MetaCyc: PWY-6981;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70263;Reactome: R-HSA-6798695;MetaCyc: PWY-6142;MetaCyc: PWY-5659;MetaCyc: PWY-7385;MetaCyc: PWY-6992;MetaCyc: PWY-621;MetaCyc: PWY-3801;MetaCyc: PWY-5514	"Starch biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Starch and sucrose metabolism";"D-sorbitol biosynthesis I";"Glycolysis";"Chitin biosynthesis";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Gluconeogenesis";"Neutrophil degranulation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"GDP-mannose biosynthesis";"1,3-propanediol biosynthesis (engineered)";"1,5-anhydrofructose degradation";"Sucrose degradation III (sucrose invertase)";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_044316150.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-73762	"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation"
XP_016973221.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016970621.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016974873.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016982503.2	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_016976001.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016990222.1	33	Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-937039;Reactome: R-HSA-202424;MetaCyc: PWY-7511;Reactome: R-HSA-975163;Reactome: R-HSA-205043;Reactome: R-HSA-9014325;Reactome: R-HSA-193692;Reactome: R-HSA-937041;Reactome: R-HSA-5689880;Reactome: R-HSA-168927;Reactome: R-HSA-937072;Reactome: R-HSA-975138;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-166058;Reactome: R-HSA-1257604;Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-975155;Reactome: R-HSA-975110;Reactome: R-HSA-5689896;Reactome: R-HSA-975144;Reactome: R-HSA-5607764;Reactome: R-HSA-933541;Reactome: R-HSA-445989;Reactome: R-HSA-9020702;Reactome: R-HSA-937042;Reactome: R-HSA-933542;Reactome: R-HSA-975871;Reactome: R-HSA-6811558	"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"IRAK1 recruits IKK complex";"Downstream TCR signaling";"Protein ubiquitination";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NRIF signals cell death from the nucleus";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulated proteolysis of p75NTR";"IKK complex recruitment mediated by RIP1";"Ub-specific processing proteases";"TICAM1, RIP1-mediated IKK complex recruitment";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Ovarian tumor domain proteases";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"TRAF6 mediated IRF7 activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex";"TRAF6 mediated NF-kB activation";"MyD88 cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_016985677.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-8856825	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis"
XP_044313071.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016989498.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_016975662.2	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016971261.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_016974942.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_016983776.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044312805.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_044313911.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016976066.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044314043.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016974754.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_016988565.1	11	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_016985245.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016971183.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044315509.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_044317716.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016970976.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016983836.1	6	KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010	"Vitamin B6 metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_044317964.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016983379.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016990211.1	18	MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_044315033.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_016977729.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_044317199.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472	"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_016971351.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system"
XP_044313365.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_016990924.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044316843.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016985530.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_044313164.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016973435.2	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_016985946.2	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016974998.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_016974518.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044313475.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_016985721.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016974768.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016986568.1	4	MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688	"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism"
XP_016981182.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling"
XP_016983428.1	34	Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-8939236;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-69656;Reactome: R-HSA-6807505	"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin A:Cdk2-associated events at S phase entry";"RNA polymerase II transcribes snRNA genes"
XP_016980839.1	18	Reactome: R-HSA-73614;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6611;KEGG: 00983+2.4.2.3;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1	"Pyrimidine salvage";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Drug metabolism - other enzymes";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Pyrimidine catabolism";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism"
XP_016980507.1	33	Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453	"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response"
XP_044317583.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016977624.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016985263.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_016976024.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016991559.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_016986051.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016971757.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_016970763.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016988765.2	6	Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-416993	"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors"
XP_016983566.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665	"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_044315968.1	5	Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-5205685	"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy"
XP_016974793.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016990411.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016974807.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_044314108.1	11	Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237	"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective EXT2 causes exostoses 2"
XP_016991974.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016980693.2	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_016985396.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016988185.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_016983461.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016977223.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016979608.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016975576.1	7	KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221;Reactome: R-HSA-6798695;MetaCyc: PWY-6596;Reactome: R-HSA-73817	"Purine metabolism";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis"
XP_016991187.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_016976794.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-611105;KEGG: 04660+3.1.3.16;Reactome: R-HSA-71403;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Respiratory electron transport";"T cell receptor signaling pathway";"Citric acid cycle (TCA cycle)";"Th1 and Th2 cell differentiation"
XP_044316017.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis"
XP_016976363.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016980732.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058	"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling"
XP_016972078.1	6	MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_044313730.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016979049.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433	"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_016977839.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016977692.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016970566.2	5	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-430039	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease"
XP_044317273.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016990858.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_044316919.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_016986869.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044313024.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_016968888.2	6	Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_016985144.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016975484.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_044313742.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016983126.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_016977821.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541	"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway"
XP_016980718.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-428890	"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling"
XP_016983081.2	16	Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176409	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_016985212.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016991072.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016977677.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_016979633.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_016979811.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016977945.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016971166.2	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
XP_016981908.2	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Degradation of the extracellular matrix"
XP_016987566.1	5	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling"
XP_016970970.2	3	Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350	"Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism"
XP_016988388.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016986906.2	12	Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932	"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Synaptic adhesion-like molecules"
XP_016974244.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_044317247.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_016986865.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016992132.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016977109.2	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_016989602.2	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_016986928.2	10	Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932	"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Synaptic adhesion-like molecules"
XP_016982989.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016977531.2	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016973597.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016977068.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_016973615.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_016987072.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-3371511;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-174437;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-110314	"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HSF1 activation";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Removal of the Flap Intermediate from the C-strand";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex"
XP_016971743.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_016970056.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_016990555.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016975712.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_044317116.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_016988418.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772	"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling"
XP_016977111.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_016987630.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_016984689.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016988414.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016992008.2	3	Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling"
XP_016985884.1	30	Reactome: R-HSA-68949;Reactome: R-HSA-917937;Reactome: R-HSA-2644607;Reactome: R-HSA-5676590;Reactome: R-HSA-2644606;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-2122947;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783	"Orc1 removal from chromatin";"Iron uptake and transport";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of NF-kappaB in B cells";"Circadian Clock";"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"NOTCH1 Intracellular Domain Regulates Transcription";"Prolactin receptor signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome"
XP_016975668.2	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016970429.2	5	Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695	"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation"
XP_044314705.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016975636.1	19	MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7224;MetaCyc: PWY-7222;Reactome: R-HSA-380320	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes"
XP_016976415.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016983696.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-5660862	"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
XP_016975967.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016982955.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_016982351.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016981214.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_016988932.1	12	Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802	"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3"
XP_016990650.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016985730.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016969556.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044315627.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044314259.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016990720.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016986708.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044316295.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016968987.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_044314646.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016985408.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_016984219.1	8	KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_016991862.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016988858.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016977622.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_016978536.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_016970698.1	3	Reactome: R-HSA-6807505;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016975597.2	14	MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_016981636.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016983440.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_044313358.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016971877.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_016989444.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016979940.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044317914.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016990530.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016985087.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016991483.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_016985501.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016982931.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_016976954.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_044317572.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044315751.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_016981798.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016986040.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044317079.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016991643.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_044315755.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2173796;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_044314362.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016987426.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016990516.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016986372.2	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016972098.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016986932.1	40	Reactome: R-HSA-5578749;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-5617472;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-6782135	"Transcriptional regulation by small RNAs";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Capping";"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER"
XP_016981336.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016973321.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016976629.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016980020.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_044316045.1	42	Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-977225	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Packaging Of Telomere Ends";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"DNA methylation";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Late Events";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged purine";"Meiotic recombination";"Amyloid fiber formation"
XP_016975607.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_016989672.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_016973711.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016981234.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016980028.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_016990296.1	7	MetaCyc: PWY-6122;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_016982463.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955	"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_044315061.1	5	Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3	"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_016973133.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016984645.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_016990069.2	3	Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation"
XP_016972822.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016985456.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016986038.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_044313676.1	16	Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1236394;Reactome: R-HSA-1963640;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-1250342;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-1251985	"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB4";"GRB2 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB4 signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"Nuclear signaling by ERBB4"
XP_016969482.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044317264.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016979239.2	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_016990367.2	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016984369.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016978252.1	14	MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;Reactome: R-HSA-71403;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728	"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Methylaspartate cycle"
XP_016978326.1	8	MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_016981626.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016978102.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_044315230.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_016972898.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016984318.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720	"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_016986551.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_044314932.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016979781.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_016973788.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)"
XP_016984996.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044316238.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs"
XP_016976423.2	5	KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;Reactome: R-HSA-432720	"Glycosaminoglycan degradation";"Neutrophil degranulation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis"
XP_044316530.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016980046.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs"
XP_016974693.2	4	MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_044315577.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_016976977.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-114604;Reactome: R-HSA-4420097	"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway"
XP_016986016.1	8	Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016981842.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016984922.1	5	Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32	"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_016987522.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044316578.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016991883.2	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016988743.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016974327.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016977911.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016989554.1	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016991144.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979877.2	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_016971742.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_016972748.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_016981792.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044317094.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016976403.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_044314830.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-801;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-2821;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-7901;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13	"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism"
XP_016980753.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_016980670.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016985392.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016971952.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation"
XP_016978427.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016989460.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016986223.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_016991220.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016980720.1	11	Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938	"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)"
XP_044317962.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_044316484.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016989175.1	11	Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery"
XP_016984000.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442	"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Neddylation";"UCH proteinases";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs"
XP_016983778.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_016987503.1	6	Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317	"Galactose catabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)"
XP_016987883.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016976852.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016975713.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_016980204.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-111932	"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB"
XP_016992281.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_016989937.2	56	Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761	"Neddylation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Degradation of DVL";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_016977203.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016978359.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990073.1	5	Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198	"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs"
XP_044315453.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_016987304.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016973805.1	9	MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_044317982.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016981206.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044315294.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016974892.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016981227.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016974901.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044317270.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_016970715.2	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_016970044.1	11	Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700	"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_016985732.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016975076.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016985393.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016983456.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016982554.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016974253.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_016975442.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016976156.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016979810.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016990655.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016981481.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016969900.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016984496.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016984470.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016991555.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016980125.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_044314410.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016970245.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044315864.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016977253.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_044316855.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_016979674.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_016982739.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_016980904.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_016988123.2	11	Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604	"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling"
XP_044312820.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_016969057.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_016992306.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_016972554.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044317336.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016984476.2	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_016983011.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_016984302.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_044315123.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016971591.2	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-5693565	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016971185.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016979613.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044317547.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016990940.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016972075.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044312876.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-936837	"Cation-coupled Chloride cotransporters";"Ion transport by P-type ATPases"
XP_016971278.1	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016979919.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044314846.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016988229.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_016978519.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323	"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling"
XP_016983694.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions"
XP_016990956.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_016970229.1	6	Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_016982979.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_044317261.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016989347.1	5	MetaCyc: PWY-6906;MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855	"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016975094.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016982441.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_016986425.1	9	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_044315356.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044317058.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016978324.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_016980724.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-428890;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-5693565	"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016980600.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016986266.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016985896.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016984422.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016979176.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016986722.1	9	MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-7533	"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Gliotoxin biosynthesis"
XP_016985740.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_016983489.2	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_016991426.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_016984676.1	13	Reactome: R-HSA-4420097;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1	"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"mTOR signaling pathway";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection"
XP_016986019.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-1234158;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947	"Circadian Clock";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016988208.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044313314.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016970562.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016988273.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_044317674.1	14	MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109	"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PC";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"Synthesis of PE";"Sphingolipid metabolism";"Triglyceride biosynthesis"
XP_044314351.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016985063.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016982199.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044315988.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016987528.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016970701.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016985390.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_044315629.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044314348.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016987635.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016987174.1	33	Reactome: R-HSA-6781823;Reactome: R-HSA-8939236;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-69202;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-167161	"Formation of TC-NER Pre-Incision Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation"
XP_016986506.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_016992052.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016988015.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016980288.2	10	Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-3214847	"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones"
XP_044317210.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016992076.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_016974243.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_044316868.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016970458.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_016970619.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016988166.2	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_044317913.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016980053.1	6	Reactome: R-HSA-6807878;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044313441.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016977731.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_016984798.2	5	Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-209560	"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival"
XP_016989731.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016979089.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_044315433.1	42	Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-3214842;Reactome: R-HSA-5693607;Reactome: R-HSA-8939236;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-427359;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-3214815;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-73728;Reactome: R-HSA-5625886;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-110330	"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"HDMs demethylate histones";"Processing of DNA double-strand break ends";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Amyloid fiber formation";"Meiotic recombination";"Cleavage of the damaged purine";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"HDACs deacetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"DNA methylation";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_016976763.1	20	Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04150+2.7.11.1;Reactome: R-HSA-166208	"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"Macroautophagy";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"Thermogenesis";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"HSF1-dependent transactivation";"mTOR signaling pathway";"mTORC1-mediated signalling"
XP_016971932.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_016973633.1	13	Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-5362768;Reactome: R-HSA-8866654;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-110320;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-8876725	"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"E3 ubiquitin ligases ubiquitinate target proteins";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"Translesion Synthesis by POLH";"Neutrophil degranulation";"HSF1 activation";"Protein methylation"
XP_044313888.1	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_044317243.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044317344.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016986249.1	10	Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"ABC-family proteins mediated transport";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016978027.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044315770.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430	"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_016973168.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_044313339.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_044315852.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044313933.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016988860.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016985867.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_044316808.1	5	MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403	"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_016981997.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016985356.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions"
XP_016980688.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016984388.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044315792.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_016971943.2	4	KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834	"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III"
XP_044317325.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_016978318.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016973154.2	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044313987.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_016980902.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_016990098.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044316241.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_044313444.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016988410.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016979425.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016984163.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016988368.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_016981624.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016981305.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_016982204.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044316669.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_016974028.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016974866.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016978372.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016989776.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_016985054.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016982878.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016991293.2	9	Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108	"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"snRNP Assembly";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_016975952.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_016991480.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016983401.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016990484.2	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_016982471.1	8	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_016986929.2	10	Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_016970643.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016973861.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016970818.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016983989.2	15	KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221	"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_016990647.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016990513.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_016972590.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016973012.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044317045.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016975997.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044316052.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_016984698.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_016975060.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_016976419.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016992287.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1	"Ansatrienin biosynthesis";"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism"
XP_016976806.1	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409	"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_016981668.2	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_044316925.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_016970329.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016991247.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_044314603.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_016986052.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016973181.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_044317929.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016980540.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016976517.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016991065.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044313080.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016985725.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016971735.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_016971491.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044315600.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_044315938.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-159231	"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_044313638.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016982548.2	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_016971845.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016981457.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_016986991.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_016977558.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979496.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016985328.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_044317343.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016979179.2	17	Reactome: R-HSA-1834949;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756	"Cytosolic sensors of pathogen-associated DNA";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation"
XP_016986054.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016979469.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016972506.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_016985397.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016970431.2	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016979869.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_016975200.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_016973688.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016985770.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016983890.1	52	Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-5250924	"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"mRNA Capping";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"B-WICH complex positively regulates rRNA expression"
XP_016989244.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016971592.2	7	Reactome: R-HSA-5693565;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_016991352.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016990447.2	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6983	"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis"
XP_016983275.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016982269.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription"
XP_016983089.1	24	Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399	"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy"
XP_016975126.2	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_016991255.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016986960.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016974029.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016978996.1	14	Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167290	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation"
XP_016990107.1	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_016990404.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_016978674.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016974774.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044317678.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_016981688.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016972737.1	15	Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9665233;Reactome: R-HSA-9665244;Reactome: R-HSA-9665251;Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-9652282;Reactome: R-HSA-9665247;Reactome: R-HSA-9665249;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-9634285;Reactome: R-HSA-9664565;Reactome: R-HSA-9665246	"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to neratinib"
XP_016971100.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016970419.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016989182.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_016983708.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016991834.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016970000.2	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016984638.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_016985032.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016984071.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016976746.2	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016980959.2	5	MetaCyc: PWY-7176;MetaCyc: PWY-7177;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2	"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_016987411.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016990351.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016975504.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_044316893.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044313837.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_016986226.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016979990.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044316742.1	42	Reactome: R-HSA-427359;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-73728;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886	"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged purine";"Meiotic recombination";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"HCMV Late Events";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"DNA methylation";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Opening";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_016975213.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_016975309.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_044314713.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_044316250.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016985538.1	18	KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4	"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism"
XP_044316861.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016983403.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016984613.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_016972551.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016975070.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_016983585.1	24	Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-6814122	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016984896.1	7	KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;MetaCyc: PWY-8043;MetaCyc: PWY-6840	"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis"
XP_016983028.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_016989343.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism"
XP_016984757.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016991259.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016984505.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016986058.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_044312840.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_016991142.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016983971.1	6	MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004	"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I"
XP_044315859.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016973134.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016979615.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016976508.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016990359.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_016975862.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016986962.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016982443.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_044317326.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044313749.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016976522.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016987085.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016987850.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016973164.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016973677.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044316123.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044316906.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016986866.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016991847.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_044315580.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_016973272.1	13	Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-186797;Reactome: R-HSA-2214320	"Collagen degradation";"NCAM1 interactions";"ECM proteoglycans";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Laminin interactions";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Signaling by PDGF";"Anchoring fibril formation"
XP_016988238.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_016987818.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016978559.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016989639.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3	"Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism"
XP_016980142.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-399719	"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors"
XP_016976286.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions"
XP_016976723.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016989178.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_044313555.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016983388.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016968980.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016985720.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044315681.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016976505.1	17	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_016988116.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_016980717.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-69231	"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1"
XP_016973864.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_016973175.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016972186.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_044315363.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016988861.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016986965.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016991058.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016991254.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_016988575.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_016990446.2	9	MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6983	"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis"
XP_044314649.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016985899.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016981915.2	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_044312764.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016971908.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016977670.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016983698.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_016979506.2	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_016980695.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016970046.1	11	Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044314386.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016985537.1	18	KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism"
XP_016977599.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_044317320.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044313580.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016987533.1	5	KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4	"Butanoate metabolism";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Valine, leucine and isoleucine degradation"
XP_044313819.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166	"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade"
XP_016985199.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016991494.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_016980635.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016972715.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_044314114.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes"
XP_016990923.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016979180.2	17	Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-1834949;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-3270619;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939	"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic sensors of pathogen-associated DNA";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"IRF3-mediated induction of type I IFN";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)"
XP_016974790.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016985012.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044313678.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-1251985;Reactome: R-HSA-8847993;Reactome: R-HSA-1250347;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1250342;Reactome: R-HSA-1963640;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1236394	"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"Nuclear signaling by ERBB4";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB4 signaling";"GRB2 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB4"
XP_044315894.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_044314869.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_044316485.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_016988171.2	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_016972127.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016974556.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016975263.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016984087.2	4	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines"
XP_044314411.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016970552.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044314770.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016990091.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis"
XP_016973166.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_016983740.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_044316796.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016980937.2	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_016983007.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_016983189.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_044317605.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016972069.1	14	MetaCyc: PWY-6969;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-4302	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Methylaspartate cycle";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)"
XP_016988539.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016980832.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016976615.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_016972182.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_016980167.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_044317582.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016976433.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016989287.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016971267.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016982279.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-6842	"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II"
XP_016975904.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016979253.2	10	Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-200425	"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Carnitine metabolism"
XP_016987775.1	11	KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7268;MetaCyc: PWY-7124;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7254	"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)"
XP_016986222.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_016979546.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044313540.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_044313100.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-1989781	"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Xenobiotics";"PPARA activates gene expression"
XP_016989009.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_016987262.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_016985441.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016980831.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016990903.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044316886.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016970525.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016984723.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174084	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_016991249.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_044312423.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044316124.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016971912.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_044316340.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016980340.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016974089.2	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_016981501.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016982395.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044316213.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016991200.2	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016972691.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016990648.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016975014.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_016991481.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016981170.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044312424.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016984387.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_044317928.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016976014.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-933541	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation"
XP_016978850.2	4	Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_044317933.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016982343.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016970638.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016984739.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_016984784.1	26	Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-69183;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-69205;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-8866654;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-1362277;Reactome: R-HSA-4615885;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6804114;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5358565	"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Processive synthesis on the lagging strand";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G1/S-Specific Transcription";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by REV1";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"SUMOylation of DNA replication proteins";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_016991727.2	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016980939.2	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_016979851.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_044316689.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016972595.1	25	Reactome: R-HSA-8951911;Reactome: R-HSA-9616222;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8878166;Reactome: R-HSA-8939256;Reactome: R-HSA-8931987;Reactome: R-HSA-8941326;Reactome: R-HSA-8941284;Reactome: R-HSA-8941333;Reactome: R-HSA-8939246;Reactome: R-HSA-8951936;Reactome: R-HSA-8939236;Reactome: R-HSA-8935964;Reactome: R-HSA-8939243;Reactome: R-HSA-8940973;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-8939245;Reactome: R-HSA-8939242;Reactome: R-HSA-8939247;Reactome: R-HSA-8941332;Reactome: R-HSA-8949275	"RUNX3 regulates RUNX1-mediated transcription";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates bone development";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates expression of components of tight junctions";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates genes involved in cell migration";"RUNX3 Regulates Immune Response and Cell Migration"
XP_016970020.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044314340.1	10	Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756	"Carnitine metabolism";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation"
XP_016991586.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016980828.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016982587.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016987511.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016974204.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016988250.1	7	MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-3385	"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Choline biosynthesis I"
XP_016982900.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016989424.1	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109	"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Neutrophil degranulation";"Triglyceride biosynthesis"
XP_016971637.1	12	KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9	"Galactose metabolism";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism"
XP_044316083.1	42	Reactome: R-HSA-201722;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-73728;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-2299718	"Formation of the beta-catenin:TCF transactivating complex";"Packaging Of Telomere Ends";"Meiotic synapsis";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Opening";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"DNA methylation";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Late Events";"G2/M DNA damage checkpoint";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Condensation of Prophase Chromosomes"
XP_016991731.2	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016984785.1	26	Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-4615885;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6804114;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-1362277;Reactome: R-HSA-5696400;Reactome: R-HSA-8866654;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-69205;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-69183	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"SUMOylation of DNA replication proteins";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"Dual Incision in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G1/S-Specific Transcription";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand"
XP_016988566.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
XP_016974455.2	6	Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_044316130.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016979103.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_044315027.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_016986176.1	7	MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897	"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes"
XP_016990184.2	5	Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_016987777.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016985129.2	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_016985311.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_016977913.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_016985386.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_044317570.1	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_016982287.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016990681.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I"
XP_016986702.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016971904.2	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_016973642.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_044317353.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_016984691.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016989510.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_016990591.2	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_044314260.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044313936.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_016990074.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499	"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane"
XP_016978304.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_044317717.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016985782.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_016984198.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016972539.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016989553.2	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016989509.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation"
XP_016969072.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016973180.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6317	"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)"
XP_044316842.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_016989440.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016982178.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044313593.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_016980737.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016990257.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016970340.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582	"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)"
XP_044317246.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016975722.1	4	KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193	"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016985620.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044312937.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016981152.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_016989769.2	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;MetaCyc: PWY-7039	"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Glycerophospholipid metabolism";"Synthesis of PG";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule"
XP_016981486.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_016985395.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016990839.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_016986422.1	27	Reactome: R-HSA-5250924;Reactome: R-HSA-195253;Reactome: R-HSA-5674400;Reactome: R-HSA-5467337;KEGG: 05170+2.7.11.1;Reactome: R-HSA-399956;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;KEGG: 04151+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-198323;Reactome: R-HSA-75815;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5610783;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-8939902;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453	"B-WICH complex positively regulates rRNA expression";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by AKT1 E17K in Cancer";"APC truncation mutants have impaired AXIN binding";"Human immunodeficiency virus 1 infection";"CRMPs in Sema3A signaling";"Human papillomavirus infection";"Relaxin signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"PI3K-Akt signaling pathway";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"AKT phosphorylates targets in the cytosol";"Ubiquitin-dependent degradation of Cyclin D";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of GLI2 by the proteasome";"Thermogenesis";"GLI3 is processed to GLI3R by the proteasome";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Regulation of RUNX2 expression and activity";"Human cytomegalovirus infection";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response"
XP_016974459.2	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044316508.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016982054.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_016990099.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016972500.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016991186.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_016991904.2	7	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_016987778.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69091	"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Polymerase switching"
XP_016988391.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_016975622.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016990974.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990662.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016972050.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_016984642.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_016982480.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016989285.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_016969332.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016976943.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044312425.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016976645.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016975517.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756	"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Synthesis of PC";"Neutrophil degranulation";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation"
XP_016992169.2	56	Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974	"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway"
XP_016972656.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_016989845.1	13	KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II"
XP_044314759.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_016976176.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977321.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044316091.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044312841.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_016980209.1	10	Reactome: R-HSA-70171;KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003	"Glycolysis";"Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol"
XP_016988574.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_016973129.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016985246.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
XP_016989141.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_016979263.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016984688.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016969913.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016973700.1	10	MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11	"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Pentose phosphate pathway";"Methane metabolism"
XP_044315825.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016970077.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979217.1	30	Reactome: R-HSA-69202;Reactome: R-HSA-9634638;Reactome: R-HSA-6804758;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-5218920;Reactome: R-HSA-199418;Reactome: R-HSA-9614399;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804759;Reactome: R-HSA-198323;Reactome: R-HSA-198693;Reactome: R-HSA-389357;Reactome: R-HSA-392451;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8876198;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-111447;Reactome: R-HSA-1257604;Reactome: R-HSA-8941332;Reactome: R-HSA-69656;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-211163;Reactome: R-HSA-5674400;Reactome: R-HSA-8948751	"Cyclin E associated events during G1/S transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of TP53 Activity through Acetylation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Downregulation of ERBB2:ERBB3 signaling";"VEGFR2 mediated vascular permeability";"Negative regulation of the PI3K/AKT network";"Regulation of localization of FOXO transcription factors";"Thermogenesis";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Association with Co-factors";"AKT phosphorylates targets in the cytosol";"AKT phosphorylates targets in the nucleus";"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma";"PI3K-Akt signaling pathway";"RAB GEFs exchange GTP for GDP on RABs";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"Activation of BAD and translocation to mitochondria";"PIP3 activates AKT signaling";"RUNX2 regulates genes involved in cell migration";"Cyclin A:Cdk2-associated events at S phase entry";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"CTLA4 inhibitory signaling";"AKT-mediated inactivation of FOXO1A";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN stability and activity"
XP_016976881.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016969329.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016980222.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_016973355.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016985354.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016985025.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_016983205.2	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016976625.1	11	MetaCyc: PWY-5497;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;MetaCyc: PWY-6596;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-6538;MetaCyc: PWY-5695	"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Purine metabolism";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Adenosine nucleotides degradation I";"Purine catabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation"
XP_016982003.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1"
XP_016977987.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_044314941.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044315771.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_044313076.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016982111.1	8	Reactome: R-HSA-73614;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-7181;MetaCyc: PWY-6556;MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5	"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes"
XP_016985303.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-1483166	"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glycerol degradation I";"Synthesis of PA"
XP_016968994.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016977059.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016992136.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016990753.2	7	MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-7238	"Starch degradation V";"Neutrophil degranulation";"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Sucrose biosynthesis II"
XP_016979414.2	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_044315806.1	5	Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983	"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)"
XP_016984841.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016979055.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016988589.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016987742.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016987297.2	5	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling"
XP_016981540.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044316537.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_016980341.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016982304.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_044313144.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_016980356.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016972035.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_016974242.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_044315289.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_016979369.1	11	MetaCyc: PWY-6964;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2	"Ammonia assimilation cycle II";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis"
XP_016970784.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016986527.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892	"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_016979855.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_016969631.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016980947.2	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_016975618.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_016970549.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016991251.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_044312420.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016988598.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_016984998.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016991109.2	17	MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-6627;MetaCyc: PWY-6620;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202	"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Purine salvage";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Arsenate detoxification I (mammalian)"
XP_044312966.1	5	KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_044315099.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749	"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated"
XP_016983692.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_044314119.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_044314938.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_016979929.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044316780.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7411	"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)"
XP_016989502.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016984501.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044314164.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_016975556.1	29	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69541;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-349425;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;KEGG: 04150+2.7.11.1	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human papillomavirus infection";"Stabilization of p53";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"mTOR signaling pathway"
XP_016990108.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803205	"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_016977554.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979621.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_016969081.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_044315712.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016970246.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016987824.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016989756.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-3642279;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer"
XP_016986979.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_016985597.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016976620.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016971392.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044312799.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_016981035.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_016989074.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044314651.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016987762.1	3	MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9	"Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_016974062.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_016986018.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_016985693.2	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_016972373.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_016986916.1	8	Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_016979194.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_016969553.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016970762.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016979021.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016985980.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events"
XP_016981946.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016990644.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016977792.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_044317922.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016983221.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_044317669.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_016986265.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016972504.2	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_016988770.2	6	Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993	"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors"
XP_044315244.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016986902.2	12	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"NrCAM interactions";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_044314361.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016985162.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016969321.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016974278.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange"
XP_016971787.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_016990812.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016988200.2	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_044317633.1	3	MetaCyc: PWY-7210;KEGG: 00240+3.5.4.12;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_016985555.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_016970482.2	7	Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531	"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus"
XP_016978145.2	5	KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;MetaCyc: PWY-6892	"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_016986006.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_044315614.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_016982110.1	8	MetaCyc: PWY-7181;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7193;Reactome: R-HSA-73614;Reactome: R-HSA-6798695	"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Neutrophil degranulation"
XP_016990734.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016972137.2	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_044314350.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016988777.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016986095.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis II"
XP_016974324.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016988767.2	6	Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993	"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors"
XP_044313812.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979515.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_016982384.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_044316941.1	14	MetaCyc: PWY-5104;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5057;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5078;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5108	"L-isoleucine biosynthesis IV";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"L-valine degradation II";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine degradation II";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis V"
XP_016986022.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-1234158;Reactome: R-HSA-3371568;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082	"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression by Hypoxia-inducible Factor";"Attenuation phase";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression"
XP_016981400.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_016984963.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_016979807.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044317827.1	8	Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-2301;MetaCyc: PWY-6580;MetaCyc: PWY-6372	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_016985733.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016985389.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016970018.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016992075.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_016988643.1	4	KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22	"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism"
XP_016981384.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016971635.1	12	KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238	"Pentose and glucuronate interconversions";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Galactose metabolism";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II"
XP_044314355.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016985541.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044317952.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016986870.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016978618.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016986538.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_016981217.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016974395.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016991469.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016971945.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_016985077.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990902.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016982557.2	21	MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7219;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Thiamine metabolism"
XP_044315654.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016975647.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_016977530.2	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_044312992.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509	"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"DAG and IP3 signaling"
XP_016979514.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7410;MetaCyc: PWY-7736	"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis"
XP_044317923.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_044313912.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016986021.1	26	Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3371568;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082	"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Attenuation phase";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression"
XP_044317979.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016988776.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016975750.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016982075.1	18	KEGG: 00620+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-70895;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-6783984;MetaCyc: PWY-5046;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00020+1.8.1.4	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Valine, leucine and isoleucine degradation";"Citric acid cycle (TCA cycle)";"Branched-chain amino acid catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Propanoate metabolism";"Tryptophan metabolism";"Lysine catabolism";"Glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine, serine and threonine metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_016983132.1	3	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_016971104.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016982091.2	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism"
XP_016984319.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-163615	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"PKA activation"
XP_016978315.1	5	KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185;MetaCyc: PWY-7210	"Purine metabolism";"Neutrophil degranulation";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_016989664.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044315009.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016983395.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044314332.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016990353.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016989108.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044313771.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016986572.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016982017.2	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_016969389.2	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_016972605.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044313344.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016987981.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_044316614.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016990486.2	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_016972277.2	10	Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-400206	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha"
XP_016980618.2	7	Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_016984793.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016971336.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016981933.1	6	KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
XP_016975960.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_016976413.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016990540.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178	"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_044313854.1	17	MetaCyc: PWY-5695;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-6627;MetaCyc: PWY-6620	"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Purine salvage";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage"
XP_016981044.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016989944.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_016971486.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016983391.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016987120.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044317468.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016977836.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016981423.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_016972081.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_016985788.1	12	MetaCyc: PWY-6613;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.3.1;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;MetaCyc: PWY-6277;MetaCyc: PWY-6121	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_016974342.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044314589.1	7	Reactome: R-HSA-212676;Reactome: R-HSA-373753;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-3000170;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Dopamine Neurotransmitter Release Cycle";"Nephrin family interactions";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Syndecan interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016974808.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016987669.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73930	"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"
XP_016980951.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016975562.2	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_044316313.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-174411	"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Polymerase switching";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere"
XP_016975084.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_016978963.1	10	Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-7328;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism"
XP_016981534.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044317932.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016990658.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016972361.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016985306.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044312767.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016981743.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823	"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation"
XP_016974178.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016970030.2	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_016985137.2	4	Reactome: R-HSA-1614558;KEGG: 00920+2.8.1.1;MetaCyc: PWY-7927;MetaCyc: PWY-5350	"Degradation of cysteine and homocysteine";"Sulfur metabolism";"Sulfide oxidation IV (mitochondria)";"Thiosulfate disproportionation IV (rhodanese)"
XP_016973145.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016990679.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_016988741.1	3	KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle"
XP_016969139.2	13	MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5913	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)"
XP_016976410.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-72649	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"Translation initiation complex formation"
XP_016987565.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016971275.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_044315088.1	5	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_016973800.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016990970.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044316911.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016978587.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_044316704.1	5	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_016977388.1	6	MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_016987184.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044313886.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016979630.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044315856.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016986969.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_016971265.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044316888.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044317823.1	10	KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Galactose metabolism";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation"
XP_016984952.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_044316005.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016969650.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_044313318.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_016984906.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016982391.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016974060.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016989690.2	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_044316866.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016973524.2	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_016981470.2	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016985168.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180910	"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs"
XP_016990093.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_044316538.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway"
XP_044313813.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016984221.1	8	KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171	"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis"
XP_016973721.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016974033.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016990491.2	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_016978538.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_016990224.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016984328.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_016981236.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016990916.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016972686.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016976791.1	14	Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"Intraflagellar transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Macroautophagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_044317675.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016978439.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_016975095.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_044316903.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016991270.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"Ub-specific processing proteases";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_016989668.1	9	MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_016973165.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_016981606.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"PKA activation in glucagon signalling";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events"
XP_016985669.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016982663.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044316885.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016974394.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016986516.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_016979628.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016984506.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_044312804.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016969626.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_044313588.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016985283.1	20	KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-5172;MetaCyc: PWY-6969;Reactome: R-HSA-1268020;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-6728;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5	"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Mitochondrial protein import";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_016976689.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016976982.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_016989849.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
XP_044313340.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_016987316.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_016973639.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
XP_016973528.2	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016980220.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-936837	"Signaling downstream of RAS mutants";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases"
XP_016986864.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016989786.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_016983590.1	9	MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12	"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis"
XP_044317730.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_044314832.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016989829.2	16	Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-6811558;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-3134963;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-975110;Reactome: R-HSA-975155;Reactome: R-HSA-5602680;Reactome: R-HSA-5603037;Reactome: R-HSA-1257604;Reactome: R-HSA-209543	"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"ER-Phagosome pathway";"Interleukin-1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 dependent cascade initiated on endosome";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR5)";"PIP3 activates AKT signaling";"p75NTR recruits signalling complexes"
XP_016987185.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977107.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_044313117.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016984983.2	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_044312823.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016985918.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_016990652.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044317920.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016984161.2	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_016971483.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016983505.2	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_016978523.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379	"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events"
XP_044314652.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016989663.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044314585.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_016984878.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016985280.1	20	Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-6728;Reactome: R-HSA-75105;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-6969;MetaCyc: PWY-5537	"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Mitochondrial protein import";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V"
XP_016983443.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044315426.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016987376.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1250196;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509	"Phosphatidylinositol signaling system";"SHC1 events in ERBB2 signaling";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling"
XP_016986032.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016970781.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016986180.1	7	Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2	"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism"
XP_016985902.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016984112.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_044316749.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_016983434.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016991012.2	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_044313015.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016970282.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016987820.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016977912.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016978255.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016985973.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016969561.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016969874.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016982399.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016987110.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_016971262.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_016988385.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_044312908.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_016976249.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016986796.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_016979337.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016976674.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016974248.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016980582.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016972688.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016982278.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Glutathione metabolism"
XP_016970241.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016975021.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway"
XP_044312835.1	31	MetaCyc: PWY-8047;MetaCyc: PWY-7858;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-5142;MetaCyc: PWY-5989;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-6799;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;MetaCyc: PWY-7663;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-8012;MetaCyc: PWY-8049;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-5971;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5973;MetaCyc: PWY-5366;MetaCyc: PWY-5994	"Bryostatin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"Pederin biosynthesis";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)"
XP_016987739.2	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_016979426.2	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044312934.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016975931.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016983697.2	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_044317829.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis"
XP_016988187.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_044315990.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016975113.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016983009.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_016986877.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016981421.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_044313938.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Ub-specific processing proteases";"Regulation of PTEN stability and activity"
XP_016976598.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016972183.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_016984695.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_016980163.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_044316242.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016980943.2	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_016981153.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_044316591.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016975696.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016988775.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016983532.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979102.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016988261.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044316239.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_016971263.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_016984886.1	9	Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695	"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"Neutrophil degranulation"
XP_016976677.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016970742.2	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_016990302.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_016985202.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016990100.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016974103.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016978312.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044313729.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016974499.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016982245.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016972275.2	10	Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022702	"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands"
XP_016979040.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism"
XP_016990682.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_016979448.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016976250.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016984158.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016989533.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016983992.1	15	MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-7218;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40	"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Rubisco shunt";"Glycolysis / Gluconeogenesis"
XP_044315915.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)"
XP_016984150.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044313357.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016988237.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway"
XP_044314228.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_016975621.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016982041.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_016981625.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016976931.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_016969948.1	10	MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10	"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Butanoate metabolism";"PPARA activates gene expression";"Terpenoid backbone biosynthesis"
XP_016982849.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016986685.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016969675.2	9	Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome"
XP_016969423.2	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_016975680.1	6	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016975748.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471	"EPHB-mediated forward signaling";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_016989770.2	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PG";"Synthesis of PA";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Ether lipid metabolism"
XP_016982907.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016979838.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-381038;Reactome: R-HSA-5358346	"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis"
XP_016972572.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_016974979.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016980410.2	3	Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_016989679.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016976182.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016974765.1	24	Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148	"Kinesins";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044314787.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016974732.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_016990199.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_016975448.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044313947.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13	"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_016982392.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016972626.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016989109.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044316541.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling"
XP_016974344.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016971490.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044317985.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis"
XP_016969791.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016976830.2	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044316799.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016982718.2	42	MetaCyc: PWY-7726;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7007;MetaCyc: PWY-6583;MetaCyc: PWY-7778;MetaCyc: PWY-7216;MetaCyc: PWY-1361;MetaCyc: PWY-7654;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-7656;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-6435;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-6946;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7401	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Caprolactam degradation";"Geraniol degradation";"Fatty acid degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol I";"2-methylpropene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Propanoate metabolism";"Glutaryl-coa degradation";"Fatty acid elongation";"Butanoate metabolism";"Benzoate degradation";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"Toluene degradation";"alpha-Linolenic acid metabolism";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"Fatty acid salvage";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Methyl tert-butyl ether degradation";"Spodoptera littoralis pheromone biosynthesis";"Limonene and pinene degradation";"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)"
XP_044312955.1	9	Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69183	"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand"
XP_044312452.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_016991066.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016990321.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982509.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016982225.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_016990869.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_044313733.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_044312806.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_016987402.2	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_044313074.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016984465.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016972616.2	4	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_016986419.1	9	Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_016975180.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_044317275.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_016991879.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016982545.2	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_016987509.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016970563.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016980696.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016968873.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_016977106.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_016980647.2	10	Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6362	"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_016973593.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016970800.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_044317305.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016988109.2	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016978272.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016974573.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_044313445.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016980946.2	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_016984512.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-983168;Reactome: R-HSA-5205685	"Aggrephagy";"Amyloid fiber formation";"Josephin domain DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy"
XP_016974374.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-445144	"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Synthesis of PC";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1"
XP_016981874.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_044317260.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016979251.2	10	Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-1632852	"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Macroautophagy"
XP_016971280.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_016986737.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044313915.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016982794.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517	"Ca2+ pathway";"cGMP effects";"Rap1 signalling"
XP_016986328.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016982163.1	15	Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated"
XP_044314327.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016982177.1	3	Reactome: R-HSA-5173214;Reactome: R-HSA-189085;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Digestion of dietary carbohydrate";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016979545.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016984137.2	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016970247.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044317567.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016987165.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_016981148.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016979671.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_044314833.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016975040.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_016985165.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016982593.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016981346.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_016976766.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Photosynthesis";"ATP biosynthesis"
XP_016988484.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_016989425.1	5	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-6798695	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Neutrophil degranulation"
XP_016988547.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_016986927.2	8	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_016971105.1	12	Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;MetaCyc: PWY-5278	"Transport and synthesis of PAPS";"Sulfur metabolism";"Monobactam biosynthesis";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenate reduction";"Selenocompound metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Sulfite oxidation III"
XP_044312844.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_044317324.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_016988360.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044314953.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_016985170.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism"
XP_016976521.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016976065.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_016973064.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_016981506.1	4	MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_016983835.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_044312440.1	13	Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-450302	"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation"
XP_016985718.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016974387.1	5	Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426	"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_016989818.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_044317215.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044315239.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016978557.1	20	Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400	"Processing of DNA double-strand break ends";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER"
XP_016981953.2	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-7115	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_016977368.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016978846.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016990927.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016988748.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016980116.1	9	MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204	"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_016986704.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016981736.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_016977957.2	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_016982294.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044312918.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_016985357.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553	"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs"
XP_016984118.2	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_016986909.2	12	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_016970063.2	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_044314848.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016983935.2	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_016985970.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044317983.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
XP_044314877.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016975075.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis"
XP_016975673.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_016975605.2	3	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_016985678.1	15	Reactome: R-HSA-114604;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557	"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"RET signaling";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT"
XP_016968827.2	3	MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590	"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation"
XP_044313096.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016992223.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_016980463.2	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_016991646.2	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_044313168.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990631.2	5	Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001	"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade"
XP_016982627.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_016969382.2	7	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_016990975.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044316869.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016972273.2	10	Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-8936459	"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_044317919.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016986727.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016976875.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_016974631.1	18	MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801	"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS"
XP_044313359.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016981879.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016984692.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_044316006.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016973273.1	13	Reactome: R-HSA-2214320;Reactome: R-HSA-186797;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244	"Anchoring fibril formation";"Signaling by PDGF";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"ECM proteoglycans";"NCAM1 interactions";"Collagen degradation";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Extracellular matrix organization"
XP_016975212.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_016974591.1	4	KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17	"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis"
XP_016987774.1	11	MetaCyc: PWY-5913;MetaCyc: PWY-7124;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7254	"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)"
XP_016972663.1	25	Reactome: R-HSA-8935964;Reactome: R-HSA-8951936;Reactome: R-HSA-8939236;Reactome: R-HSA-8939246;Reactome: R-HSA-8941332;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8939242;Reactome: R-HSA-8940973;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8939245;Reactome: R-HSA-8939243;Reactome: R-HSA-8878166;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-9616222;Reactome: R-HSA-8951911;Reactome: R-HSA-8941333;Reactome: R-HSA-8941284;Reactome: R-HSA-8941326;Reactome: R-HSA-8939256;Reactome: R-HSA-8931987	"RUNX1 regulates expression of components of tight junctions";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional regulation by RUNX2";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Transcriptional regulation of granulopoiesis";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates estrogen receptor mediated transcription"
XP_016970045.1	11	Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700	"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_016982556.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016972418.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016983008.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
XP_016990267.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044316014.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016971947.2	1	KEGG: 00564+3.1.1.7	"Glycerophospholipid metabolism"
XP_016983198.2	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_016986786.1	6	KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124	"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II"
XP_016980925.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044317977.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044317382.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016986792.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_044315063.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016986539.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016990660.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016989428.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_016991055.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_016981771.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016981345.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044316916.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_016983801.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016979809.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016969371.1	10	Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111458	"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Formation of apoptosome"
XP_016974444.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_016982729.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_016984942.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-983168	"Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044317110.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_016987213.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_016982642.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016981777.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016984416.1	28	Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-5358606;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-69166	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Meiotic recombination";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HSF1 activation";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate"
XP_044316461.1	4	KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14	"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Nitrogen metabolism"
XP_044315000.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016972130.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_016984274.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016977394.1	8	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_016973132.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016987629.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_044316892.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016985582.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044317318.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016976409.1	12	Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-72649	"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"Translation initiation complex formation"
XP_044315818.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_016985499.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016988887.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616	"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication"
XP_016982725.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_044314591.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016984384.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016983159.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_044313491.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016990632.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016988122.2	11	Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642	"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling"
XP_016977790.2	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_016981079.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_016986934.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_016985440.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016976956.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016986764.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016977663.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016984366.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016973662.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016975747.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921	"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation"
XP_016982489.1	6	Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36	"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_016979350.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016971938.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016973419.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_016971110.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016971638.1	12	KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817	"Starch and sucrose metabolism";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Stachyose degradation";"Glycogen synthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016977208.1	17	Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_016990676.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_016990824.1	52	Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167162	"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape"
XP_016983201.2	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_016974817.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016987421.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016970876.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902	"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity"
XP_016991644.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044314896.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016973386.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016991565.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016987674.1	25	Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-380270;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9648025	"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation"
XP_016969427.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_016982665.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016977598.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016985353.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016992195.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016978903.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016983064.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_016989371.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016985566.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_016987186.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016985708.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016982924.1	16	KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5749;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.4;KEGG: 00720+6.2.1.5	"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Itaconate degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes"
XP_016987430.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016983377.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016980861.1	5	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism"
XP_016989184.2	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016986174.1	7	MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897	"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes"
XP_016980667.2	13	MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-9027277;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;Reactome: R-HSA-2871796;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"FCERI mediated MAPK activation";"DAP12 signaling";"Generation of second messenger molecules";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization"
XP_016987118.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016991965.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016992309.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016972959.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044314133.1	11	Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation"
XP_044316312.1	20	Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5685938	"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)"
XP_016969230.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016987382.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016973637.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_044314586.1	7	Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-3000170;Reactome: R-HSA-212676;Reactome: R-HSA-373753;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Syndecan interactions";"Dopamine Neurotransmitter Release Cycle";"Nephrin family interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016972727.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_016989003.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_016970662.2	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016983067.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044315601.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_044313035.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044316151.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016971136.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_016973984.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044314431.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016973408.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016986482.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_016984631.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016969880.1	4	Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975138	"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_044312800.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016971786.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_016977831.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_016984789.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016969958.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016977909.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016976454.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016984693.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_016979237.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016977833.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_016971864.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016983399.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016972233.1	57	Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091	"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells"
XP_044317333.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_016971876.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_016979210.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_016988016.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016980056.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016989072.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016986679.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_044316061.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016977705.2	56	Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-195253	"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex"
XP_016985722.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044314316.1	7	Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_016986079.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_016990859.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016982793.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
XP_044315616.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016982173.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_016974094.2	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_016975247.2	4	MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-6829	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"Trna methylation (yeast)"
XP_016976159.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722	"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_016979097.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016980358.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016982116.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044315826.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016988769.2	6	Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-416993	"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors"
XP_044314324.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044314383.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016975282.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_016977476.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016975085.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_016990551.2	16	Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_016969895.2	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_016971111.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016971286.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs"
XP_016969634.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_044314895.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016988423.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772	"Signaling by Leptin";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling"
XP_016991678.2	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_016990292.1	6	KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22	"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism"
XP_044317331.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044317502.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_044312830.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016981941.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016973604.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_016973933.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016986179.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle"
XP_016981788.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016989064.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_044312824.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_016986992.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_016987253.1	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
XP_016981615.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1	"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism"
XP_044315484.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044312917.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_016973960.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_016983616.2	27	Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746	"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein"
XP_016977065.2	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis"
XP_016978860.2	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_044314419.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016976978.1	9	Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-416482;Reactome: R-HSA-5218920	"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"Rho GTPase cycle";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability"
XP_016985619.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016975439.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016980689.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016971929.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044314384.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016983178.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016977378.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044314719.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016990674.2	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_016984147.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044316863.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016975441.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016986910.2	12	Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_016976553.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016973428.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_016972074.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016974417.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016987684.2	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_016973136.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016987648.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016987538.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016973262.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016984361.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016969228.2	12	Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_016987926.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_044312467.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016971758.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_016983421.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_016977506.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044313066.1	5	KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism"
XP_016979672.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044316004.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016969649.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_016986024.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606	"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044315769.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_016972054.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016982300.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044312715.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016992064.2	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_016985829.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_016970499.2	14	MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7036	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_016974092.2	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_044312932.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016975947.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016979760.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044316521.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_016971369.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_044315862.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044314872.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016974742.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016977890.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_016969651.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016985444.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044317022.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6807505	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes"
XP_044317113.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_016982466.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_044315435.1	42	Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-3214842;Reactome: R-HSA-5693607;Reactome: R-HSA-8939236;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-5625886;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-427413	"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Amyloid fiber formation";"Cleavage of the damaged purine";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"HDMs demethylate histones";"Processing of DNA double-strand break ends";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"HCMV Late Events";"PRC2 methylates histones and DNA";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"DNA methylation";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression"
XP_016984923.1	7	MetaCyc: PWY-7255;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_044316365.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_016984989.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016970432.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016981735.1	5	MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5381	"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)"
XP_016972622.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016990066.2	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_044313119.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016990216.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044315017.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016982070.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016972049.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016977655.2	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_016973925.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016983396.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016991976.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016991039.1	11	Reactome: R-HSA-69416;Reactome: R-HSA-9013957;Reactome: R-HSA-75157;Reactome: R-HSA-5357786;Reactome: R-HSA-933543;Reactome: R-HSA-5218900;Reactome: R-HSA-140534;Reactome: R-HSA-2562578;Reactome: R-HSA-75158;Reactome: R-HSA-5213460;Reactome: R-HSA-3371378	"Dimerization of procaspase-8";"TLR3-mediated TICAM1-dependent programmed cell death";"FasL/ CD95L signaling";"TNFR1-induced proapoptotic signaling";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"CASP8 activity is inhibited";"Caspase activation via Death Receptors in the presence of ligand";"TRIF-mediated programmed cell death";"TRAIL signaling";"RIPK1-mediated regulated necrosis";"Regulation by c-FLIP"
XP_016980235.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016988113.2	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016987168.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016970727.2	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_016982396.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016971939.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016981700.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016978920.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016986128.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_016990245.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_016989365.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016981459.2	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_016971108.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016970757.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016981585.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_016971518.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300	"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors"
XP_016974211.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016983392.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044316858.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_044317195.1	11	KEGG: 00240+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7400;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_016988772.2	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation"
XP_016985398.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016976330.2	27	Reactome: R-HSA-975957;Reactome: R-HSA-112382;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-167200;Reactome: R-HSA-191859;Reactome: R-HSA-9010553;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-975956;Reactome: R-HSA-167242;Reactome: R-HSA-159227;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of RNA Pol II elongation complex";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"snRNP Assembly";"Regulation of expression of SLITs and ROBOs";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP independent Mature mRNA";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_016988865.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016971891.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-1655829	"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_016984823.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_016988811.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-174437	"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand"
XP_016975595.2	14	MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_016984096.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661	"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation"
XP_044317953.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016981485.2	15	Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262	"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_044314584.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044316879.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044314113.1	11	Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation"
XP_016987826.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016983027.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_016981030.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016983402.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016981297.1	5	KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-6798695	"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation"
XP_016980359.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016980048.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_016983626.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_044314645.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044314827.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016979340.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044313159.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016985419.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_016986570.1	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism"
XP_016971253.1	8	Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Macroautophagy"
XP_044317581.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016984940.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016972063.2	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_044316136.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016971354.2	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016986555.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016982309.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016981940.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016969312.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016970642.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016980727.2	11	Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
XP_016985817.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_044316060.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016980636.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016982299.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_044312904.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_016972832.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016970961.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016975103.2	17	Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5358565	"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Polymerase switching";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_016973458.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_016973077.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044316011.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016973797.2	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_016973810.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702	"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling"
XP_016982282.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016975458.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_016970902.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016984809.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016984890.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016972062.2	4	KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199;Reactome: R-HSA-4755609;MetaCyc: PWY-6129	"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis"
XP_016983206.2	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_016971779.2	13	Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775	"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Ca2+ pathway";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis"
XP_016986829.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_016981801.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016986687.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_044313926.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_016986414.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_016979494.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016973159.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_016987825.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016972135.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_044315153.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_016974889.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_016981774.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016972826.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016969573.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016970354.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_044314847.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016975003.2	16	Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944	"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2"
XP_016977632.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016980944.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_016972095.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016982143.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016973838.1	1	Reactome: R-HSA-2168880	"Scavenging of heme from plasma"
XP_016985719.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016989720.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016976805.1	18	MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Ether lipid metabolism"
XP_016975619.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016987925.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_044314150.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016982000.2	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_016991001.2	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_016981800.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016976972.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_016970178.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044315152.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_016979393.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_044317294.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044312825.1	6	KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_016982484.2	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044314335.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016991832.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016978251.1	14	KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-5690	"Oxidative phosphorylation";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)"
XP_016979849.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016975325.2	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_016980057.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_016969367.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-983712	"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"Ion channel transport"
XP_016980353.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016980151.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736	"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors"
XP_016981813.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016985554.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016991489.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016988398.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_016977586.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016986321.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016982461.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955	"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_016979041.1	10	MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2	"Stachyose degradation";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism"
XP_016987997.2	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_016991373.2	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044312602.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_016976379.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016970759.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044315997.1	5	MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
XP_016989629.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation"
XP_016977793.2	6	Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_016981479.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_016971882.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016991721.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_016991054.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_016986026.1	26	Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-1234158;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Regulation of gene expression by Hypoxia-inducible Factor";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_044317229.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5689880	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases"
XP_016971358.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_016989426.1	5	KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-6798695	"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Neutrophil degranulation"
XP_016982791.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
XP_016986546.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_016989486.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016971902.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_016972282.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016980494.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016977503.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016969951.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_016985439.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016972431.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016980505.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044313559.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044317255.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016973135.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016975366.2	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_044316769.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016989093.2	4	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_016977559.2	56	Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168	"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016982067.1	8	MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;Reactome: R-HSA-6798695	"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine salvage";"Neutrophil degranulation"
XP_016970033.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-174430	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation"
XP_016985498.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044314029.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016970468.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016976765.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980	"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Photosynthesis";"ATP biosynthesis"
XP_016969639.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation"
XP_016970733.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016977323.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_044313141.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199	"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation"
XP_016969557.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016988597.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016981878.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016974335.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016982180.1	3	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635;Reactome: R-HSA-189085	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)";"Digestion of dietary carbohydrate"
XP_016983122.1	14	MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_016983397.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016973237.1	29	Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167158	"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex"
XP_016974712.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_016986525.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016972173.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016985565.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_044314874.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_044316917.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_016976435.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044314401.1	14	MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724	"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_016986113.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016987529.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016983079.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016968874.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_016986820.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_016976255.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016985106.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_044313937.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination"
XP_016984725.1	3	Reactome: R-HSA-8953750;Reactome: R-HSA-427389;Reactome: R-HSA-73772	"Transcriptional Regulation by E2F6";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape"
XP_016988756.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_016977949.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016974241.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_016972918.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-6969	"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_016973488.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174084	"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_016981335.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016983118.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_044312614.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016971282.2	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016980417.1	3	MetaCyc: PWY-7424;KEGG: 00100+2.3.1.26;Reactome: R-HSA-8964038	"Sterol:steryl ester interconversion (yeast)";"Steroid biosynthesis";"LDL clearance"
XP_016974859.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044315134.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_016969379.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016970266.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_016980166.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-111932	"Interferon gamma signaling";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB"
XP_016980838.2	18	MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-6620;Reactome: R-HSA-73614;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-7179;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202	"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Pyrimidine salvage";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Pyrimidine catabolism";"Pyrimidine metabolism";"Purine metabolism";"Arsenate detoxification I (mammalian)"
XP_016972671.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016970547.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016989925.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174084	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_016990070.2	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016988962.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016990929.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016977964.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044314680.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-3781	"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)"
XP_016971426.2	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016969474.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044313942.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_044315355.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016971149.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016977851.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044314823.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824	"Sesamin biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis"
XP_016974881.2	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_016982477.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_016992239.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_016988764.2	6	Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-76005	"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+"
XP_016982292.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_044315540.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016980432.1	7	MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25	"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Streptomycin biosynthesis"
XP_016985385.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_044316750.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_044312471.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_044313587.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044315807.1	5	MetaCyc: PWY-4983;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis"
XP_016990270.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016986763.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016987178.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016974421.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044317409.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_016974018.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_016979710.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016968993.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016982436.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_016989968.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_016982049.1	14	MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_016973383.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_016983026.2	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_016969551.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016979808.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016979341.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982385.1	3	Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
XP_016971883.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016990191.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
XP_016989876.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016978606.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_016980244.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_016981480.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016983704.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044312801.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016975067.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_016976874.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016982476.2	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_044316907.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016977479.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II"
XP_016979974.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_016986149.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016970999.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016981075.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016974652.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_016973698.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11	"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Glycolysis";"Pentose phosphate pathway";"Methane metabolism";"Fructose and mannose metabolism"
XP_044315423.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044312557.1	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
XP_016972279.2	10	Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300	"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors"
XP_016982394.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016981446.2	5	Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_044315113.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_016984921.1	5	MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_016983477.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_016980245.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044314754.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_016986229.2	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_016980423.1	52	Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-76066;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-203927;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"MicroRNA (miRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation"
XP_016983082.2	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016971238.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016986124.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016973590.1	10	Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016980723.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-69231	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1"
XP_044313428.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016974494.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016976163.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_016978070.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016985700.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016982897.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_044314976.1	9	MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism"
XP_016974629.1	18	Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;MetaCyc: PWY-7783	"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Plasmalogen degradation"
XP_016985394.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016982198.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016969707.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044312708.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_044314242.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_016987645.1	4	KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_044316525.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016987371.1	6	Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-1250196	"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling"
XP_016972093.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016985826.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159231	"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_016971168.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016982901.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016984909.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_016990077.2	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_016978967.1	57	Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-75815	"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D"
XP_016981419.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_016977477.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016971489.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016981619.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_016984072.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016973860.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709	"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins"
XP_016991351.1	6	MetaCyc: PWY-5514;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_016992183.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_016991253.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_044313319.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_016975870.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044314418.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016971087.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016988774.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016972739.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044315364.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016978585.2	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016985097.2	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_016972806.2	11	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_016990122.1	7	Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16	"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_016984449.2	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Activation of RAC1";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_016972240.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_016973277.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016984042.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_016973803.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_016986381.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_016975604.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016990382.1	9	Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827	"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_016988881.2	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_016971825.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016990207.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016983705.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016987506.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016973668.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016985709.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016971781.2	13	Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-381676	"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_016972886.1	2	Reactome: R-HSA-9614657;Reactome: R-HSA-5205685	"FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy"
XP_044313556.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016990968.2	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016981594.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016983524.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877	"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase"
XP_016990515.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016979837.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016975729.1	9	MetaCyc: PWY-6118;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8	"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism"
XP_016987016.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044314878.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016987578.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016972132.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016975362.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016974015.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_044312995.1	9	Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932	"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules"
XP_044317249.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016988587.1	8	KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_016971289.2	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016989187.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016979174.2	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016983781.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_044317484.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044313776.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_016982417.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_016971600.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044313312.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016986755.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_016973174.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016978665.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016974343.1	4	Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044315353.1	25	Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-381771;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events"
XP_016986369.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016976853.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016988453.2	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_016983390.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_044316506.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016989557.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016969327.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016986900.2	12	Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"NrCAM interactions";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_016989462.2	7	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-140837;Reactome: R-HSA-8957275	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation"
XP_016982244.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_044312935.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_044317441.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016978253.2	2	Reactome: R-HSA-1237044;KEGG: 00520+1.6.2.2	"Erythrocytes take up carbon dioxide and release oxygen";"Amino sugar and nucleotide sugar metabolism"
XP_016970330.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016988199.2	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_016969399.2	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_016971442.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_016975365.2	5	KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism"
XP_044313851.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044317526.1	14	MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
XP_016992221.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016970240.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016988367.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016988092.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_016987569.2	12	Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13	"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms"
XP_016981617.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway"
XP_044316156.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_016973594.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016982414.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_016975975.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_016989961.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016982438.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_016974550.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016982465.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355	"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction"
XP_016981726.1	3	Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-8953750	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional Regulation by E2F6"
XP_016985583.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016973130.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016974851.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-165054	"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA"
XP_016987175.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_016985762.1	7	MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway"
XP_016980598.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016973636.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-983231	"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production"
XP_044316245.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_016985898.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016972670.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016986958.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016991037.2	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016975575.2	7	Reactome: R-HSA-983231;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-9018519	"Factors involved in megakaryocyte development and platelet production";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"Estrogen-dependent gene expression"
XP_016986447.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016982911.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016982285.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016969776.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016982775.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016976139.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016980573.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_016972425.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016983475.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016969656.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Neutrophil degranulation";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_016985224.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016975066.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_016983866.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016986181.1	7	Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2	"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis"
XP_016984139.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016980212.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-111932	"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB"
XP_016984818.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016985704.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016983739.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_016981420.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_016981719.2	4	Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping"
XP_044317349.1	7	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-140837;Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-114608	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events";"Platelet degranulation"
XP_016976827.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568	"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Attenuation phase"
XP_044312933.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016973962.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_016983985.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016987290.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_016976657.2	15	MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_044314625.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_016980873.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016980188.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952	"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions"
XP_016975620.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_016978204.1	8	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Macroautophagy";"mTOR signalling"
XP_044314420.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016984628.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016976919.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-380284	"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_016973897.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_016991368.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016976606.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_044313078.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016976515.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Neutrophil degranulation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_016974045.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016974697.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016985324.1	5	KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_016982064.1	8	Reactome: R-HSA-74217;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1	"Purine salvage";"Neutrophil degranulation";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II"
XP_016991496.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016971636.1	12	MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238	"Stachyose degradation";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Galactose metabolism";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II"
XP_044316598.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016986761.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_044313169.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016983274.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016985005.2	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis"
XP_016972897.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016971896.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_016991872.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_016986678.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016969465.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_016988757.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_016983761.1	56	Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178	"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_044316110.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_044314416.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016989891.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016973456.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_016984637.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016969033.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8957275	"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"VLDL assembly";"Scavenging by Class A Receptors";"VLDL clearance";"Retinoid metabolism and transport";"Post-translational protein phosphorylation"
XP_016978923.1	13	KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5690	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)"
XP_016973405.2	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_016974377.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751	"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Synthesis of PC";"WNT mediated activation of DVL";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity"
XP_016978944.2	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_016991467.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016988164.2	6	Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64+3.1.3.95;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;MetaCyc: PWY-6580;MetaCyc: PWY-6368	"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation"
XP_016989060.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016980162.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016974557.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016976512.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016990976.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016991291.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044316900.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016973148.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990866.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016981808.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016975165.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016990865.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016979829.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016986756.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_016984446.2	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016986847.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016969672.1	8	Reactome: R-HSA-70635;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4983;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-5154;MetaCyc: PWY-5	"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis"
XP_016988370.2	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_044316141.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016982932.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_016982284.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_044315292.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044315861.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016981912.1	52	Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-76061;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-72086	"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"mRNA Capping"
XP_016974792.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_044312846.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_016982016.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044317244.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016988779.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016979200.1	2	Reactome: R-HSA-5655302;Reactome: R-HSA-1839117	"Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants"
XP_044312505.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016977808.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_016983583.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-163359	"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation"
XP_016979284.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016979218.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016970023.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_016974789.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016978879.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016979154.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_016981623.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016977927.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016986860.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016984351.1	9	Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_016982659.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044314402.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016970275.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_044315108.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016986717.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016990659.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016980563.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044313315.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016970783.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044316697.1	20	MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735	"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Jasmonic acid biosynthesis"
XP_016969000.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016970672.2	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016989281.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_016985211.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_044312539.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016976627.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016978847.1	13	Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-7533	"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Gliotoxin biosynthesis"
XP_016972170.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974	"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway"
XP_016974306.1	4	KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270;MetaCyc: PWY-4261	"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate";"Glycerol degradation I"
XP_016985463.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016979753.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_016975728.1	9	MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8	"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism"
XP_016980515.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016976051.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_016981034.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016974205.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016973963.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016986688.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_016980945.2	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_016983321.2	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_044316040.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_044316507.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044316865.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016985461.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016978031.2	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_016972465.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016976063.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1"
XP_016989716.1	57	Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-5689880	"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases"
XP_044314149.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016980495.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016988111.2	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_016988017.2	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_016974555.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016983815.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_044312956.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_016971730.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044312586.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016977914.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_016977952.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016980399.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361	"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_016986793.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_016984503.2	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_016980352.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016987552.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_016988549.1	13	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-5674400	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_016987097.1	12	MetaCyc: PWY-5870;Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5872	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_016976644.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4551638	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins"
XP_016980190.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044314588.1	7	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-212676;Reactome: R-HSA-373753;Reactome: R-HSA-3000170;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Dopamine Neurotransmitter Release Cycle";"Nephrin family interactions";"Syndecan interactions";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_044313544.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_044316797.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016983930.1	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"Oxidative phosphorylation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_016980702.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016987291.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_016979043.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016989674.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016982027.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_044315660.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_044316070.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_044315096.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257	"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion"
XP_016984009.2	9	MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8	"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism"
XP_016972426.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_016981279.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_016990393.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016986822.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_016970696.1	3	Reactome: R-HSA-6807505;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044316703.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016969331.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016988097.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016972730.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016977787.2	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_016984497.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016979298.2	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016973760.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_044314121.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_016987513.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_016979293.1	4	MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59	"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_044315991.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044314784.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016972407.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_016987265.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016983911.2	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism"
XP_016974753.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_016982113.1	8	Reactome: R-HSA-73614;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-6556	"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II"
XP_016972024.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016989004.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_016974941.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_016982792.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
XP_044312403.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044312665.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016979802.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016983521.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy"
XP_016987162.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_016991561.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_044316287.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016982073.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_044317900.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016989755.1	9	Reactome: R-HSA-2173789;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603	"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases"
XP_016988864.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016973284.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016976424.2	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14	"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation"
XP_016984644.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_044312925.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_016990937.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_044315542.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044317697.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016979660.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-7587	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)"
XP_016977097.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016982189.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016974867.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016977956.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_016979860.2	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_016985805.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016986754.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016991237.1	6	MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_016989089.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_016969678.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_044317179.1	3	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-8854214	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"TBC/RABGAPs"
XP_016982660.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016986413.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016980734.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_044315805.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983	"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)"
XP_016982085.2	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism"
XP_016986913.2	10	Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"NrCAM interactions";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_016969583.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_016988230.2	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_016986874.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016982909.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016976608.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_044315824.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016989874.2	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_016972501.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016982167.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_044317592.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_016969677.2	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_016979261.2	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_016972234.1	57	Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5658442	"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Neddylation";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Downstream TCR signaling";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs"
XP_016969246.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016976563.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016980834.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016991369.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990042.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016980830.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_016975746.1	19	Reactome: R-HSA-8950505;Reactome: R-HSA-114604;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-428543;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-2029482;Reactome: R-HSA-5627123;Reactome: R-HSA-182971;Reactome: R-HSA-5663220;Reactome: R-HSA-983231;Reactome: R-HSA-8964616;Reactome: R-HSA-5687128;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-525793;Reactome: R-HSA-5663213	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"Inactivation of CDC42 and RAC1";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate PAKs";"EGFR downregulation";"RHO GTPases Activate Formins";"Factors involved in megakaryocyte development and platelet production";"G beta:gamma signalling through CDC42";"MAPK6/MAPK4 signaling";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"Rho GTPase cycle";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs"
XP_016969636.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016980862.1	5	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_016970780.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016975199.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_016982716.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_016982628.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
XP_016970546.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016973929.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_016984819.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016974634.2	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016986486.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044317476.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016977340.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_044312415.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016989628.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-177929	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Signaling by EGFR"
XP_016991732.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016974007.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016983318.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_016976937.2	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_016970083.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_016988096.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016976510.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_016987472.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016980526.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044315511.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016984844.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016986903.2	12	Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-438066	"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_044312809.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016990301.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-195253	"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neddylation";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex"
XP_016986399.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6807505	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes"
XP_016976453.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016977389.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_016987244.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044312456.1	5	Reactome: R-HSA-3772470;Reactome: R-HSA-5340588;Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-4641263	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"RNF mutants show enhanced WNT signaling and proliferation";"TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Regulation of FZD by ubiquitination"
XP_016983518.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation"
XP_044314163.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_044315860.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016991221.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016986126.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_016978220.1	4	Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_016990092.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_016972916.1	13	Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-6969	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_016970243.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016991484.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_016986291.2	7	Reactome: R-HSA-9020265;Reactome: R-HSA-9023661;Reactome: R-HSA-9018676;Reactome: R-HSA-6798695;Reactome: R-HSA-9018896;Reactome: R-HSA-2142691;Reactome: R-HSA-9018681	"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of D-series resolvins";"Neutrophil degranulation";"Biosynthesis of E-series 18(S)-resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of protectins"
XP_016973275.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016989076.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_044313935.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016986804.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_044313457.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation"
XP_016970262.2	7	Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_016985436.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044317564.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_044316036.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_016971254.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016969328.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016973748.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_016977386.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_044314602.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism"
XP_044313791.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016986114.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex"
XP_016986066.1	9	Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-75955	"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation"
XP_016980498.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016984381.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_044315820.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_016976312.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016977944.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016983955.2	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_044314527.1	6	MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_016973320.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044317350.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system"
XP_044316240.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_016983779.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044316873.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016979010.2	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016982582.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016978827.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_016973596.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016985670.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_016985941.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016974030.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_044316969.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979100.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_016978607.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_016974845.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_044316786.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016980725.1	11	Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938	"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)"
XP_016990926.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044317816.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016974373.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-6814122	"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL";"Synthesis of PC";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016976582.2	3	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)"
XP_016982564.2	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_016982069.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_016982812.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044314703.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016978643.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044312965.1	5	MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_016983940.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016986065.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-2173796;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
XP_044317832.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016987534.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016979264.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_016977709.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016979844.1	10	Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23	"MPS VII - Sly syndrome";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation"
XP_016969775.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733	"Degradation of DVL";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_016988177.2	4	Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_016985167.2	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016970778.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016988740.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016981028.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044314948.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016976162.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6	"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Peroxisomal protein import";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism"
XP_016982298.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016972488.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_016983042.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016991243.2	15	MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7218;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901	"Rubisco shunt";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation"
XP_044315893.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_016982068.1	8	Reactome: R-HSA-5683826;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4	"Surfactant metabolism";"Purine salvage";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Purine metabolism"
XP_016983032.2	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016970736.2	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016979779.1	9	MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061	"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I"
XP_016980363.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044312409.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016971875.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_044315438.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016977271.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016974396.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016968857.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044315690.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044313941.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Ub-specific processing proteases"
XP_016979573.2	7	Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-168333	"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_016979172.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016990936.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016991757.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016985940.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_016975825.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332	"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Mitotic Prometaphase";"Recycling pathway of L1";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Kinesins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin"
XP_044313538.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016969956.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_016968890.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_016986640.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044313348.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016975658.2	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_016974510.1	33	Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-3108214	"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins"
XP_044316019.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59"
XP_016989333.2	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016978455.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016983741.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_016973936.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016987670.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-5651801	"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair"
XP_016977916.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016979354.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016988751.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016988479.1	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"mTOR signaling pathway";"EPHB-mediated forward signaling";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"MAPK6/MAPK4 signaling";"Relaxin signaling pathway"
XP_016987937.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016986703.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016988752.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016982058.1	8	KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;Reactome: R-HSA-5683826	"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine salvage";"Surfactant metabolism"
XP_016969381.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_016972044.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016979507.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016976796.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_016990706.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-191859	"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly"
XP_016973385.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_044315110.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016972499.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044313999.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_016986848.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016972531.2	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_044316853.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_044317815.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016988540.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016975010.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-5667	"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I"
XP_016978855.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_044315394.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016971268.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_016990931.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_044316787.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016976851.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016984742.1	4	KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)"
XP_016970790.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_016978482.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016984655.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016984651.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_016984398.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044313679.1	16	Reactome: R-HSA-2219530;Reactome: R-HSA-1963640;Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-1251985;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-1250342;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-1250347;Reactome: R-HSA-8847993	"Constitutive Signaling by Aberrant PI3K in Cancer";"GRB2 events in ERBB2 signaling";"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"Nuclear signaling by ERBB4";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"SHC1 events in ERBB4 signaling";"ERBB2 Activates PTK6 Signaling"
XP_016987844.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_016978440.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_016971240.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016984685.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044316970.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016990145.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016987114.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_044315101.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358747	"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated"
XP_016984305.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1"
XP_016973795.2	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_016975887.1	13	KEGG: 00720+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857	"Carbon fixation pathways in prokaryotes";"Ethanol oxidation";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis"
XP_016976933.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736	"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors"
XP_044316874.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016990639.2	5	Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-2219530	"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_044312398.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044313542.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_044317731.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016990847.2	1	Reactome: R-HSA-419771	"Opsins"
XP_016980503.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016977485.2	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016985070.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016984119.2	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016971458.1	17	KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-5744;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679	"Pyruvate metabolism";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis"
XP_044316244.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_016978619.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044317475.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016985870.1	4	Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211	"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes"
XP_016978377.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044317334.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016972575.1	56	Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870	"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins"
XP_016973745.1	33	Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-180910	"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs"
XP_016981499.1	16	Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167243	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery"
XP_016983177.1	7	Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_016974675.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_044313135.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016971914.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4085001;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-2206308;KEGG: 00531+3.2.1.23	"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"HS-GAG degradation";"Galactose metabolism";"Sialic acid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B";"Glycosaminoglycan degradation"
XP_016983271.1	33	KEGG: 00010+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5078;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00071+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-1801;MetaCyc: PWY-5480;MetaCyc: PWY-5076;Reactome: R-HSA-71384;MetaCyc: PWY-5082;MetaCyc: PWY-5079;MetaCyc: PWY-6342;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6802;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-6871;MetaCyc: PWY-6313;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-7396;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-7111;MetaCyc: PWY-7118;MetaCyc: PWY-5057;MetaCyc: PWY-6333;KEGG: 00982+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00626+1.1.1.1;KEGG: 00680+1.1.1.284	"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol III";"L-isoleucine degradation II";"alpha-Linolenic acid metabolism";"(S)-propane-1,2-diol degradation";"Fatty acid degradation";"L-tryptophan degradation V (side chain pathway)";"Formaldehyde oxidation II (glutathione-dependent)";"Pyruvate fermentation to ethanol I";"L-leucine degradation III";"Ethanol oxidation";"L-methionine degradation III";"L-phenylalanine degradation III";"Noradrenaline and adrenaline degradation";"Retinol metabolism";"Salidroside biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Protein S-nitrosylation and denitrosylation";"3-methylbutanol biosynthesis (engineered)";"Serotonin degradation";"Tyrosine metabolism";"Phenylethanol biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol II";"Pyruvate fermentation to isobutanol (engineered)";"Chitin degradation to ethanol";"L-valine degradation II";"Acetaldehyde biosynthesis I";"Drug metabolism - cytochrome P450";"Glycine, serine and threonine metabolism";"Naphthalene degradation";"Methane metabolism"
XP_044316895.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016969977.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_016980459.2	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016986118.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016980575.1	8	Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_016972034.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016990469.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016972573.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_016990754.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6724	"Neutrophil degranulation";"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation II"
XP_044316522.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_016976882.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016980584.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_044313586.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016988101.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_016986288.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-165054	"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA"
XP_016986978.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_016973400.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_016978768.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537	"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_016977532.2	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_044312768.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016970782.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_044316905.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016970285.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_044312412.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016978723.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016982998.1	4	KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016989855.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016988279.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016979039.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016979659.1	14	MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7782	"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis"
XP_016979836.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016970104.2	30	Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-2644606;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-1170546	"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Prolactin receptor signaling"
XP_016981779.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_044316854.1	3	Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13	"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system"
XP_044314014.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016979653.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016972687.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044314606.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016969211.1	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_044316149.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016990607.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016974815.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016975969.2	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016972247.1	7	MetaCyc: PWY-6351;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis"
XP_016990358.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_044315707.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016980599.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044316137.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016977865.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016974445.1	9	Reactome: R-HSA-9630221;Reactome: R-HSA-110331;Reactome: R-HSA-9608290;Reactome: R-HSA-9630222;Reactome: R-HSA-110330;Reactome: R-HSA-9608287;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Defective NTHL1 substrate processing";"Cleavage of the damaged purine";"Defective MUTYH substrate processing";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_016979806.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016975506.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016973529.2	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_044314635.1	42	Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-212300;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-3214815;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-73728;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118	"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Late Events";"G2/M DNA damage checkpoint";"PRC2 methylates histones and DNA";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Cleavage of the damaged purine";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Packaging Of Telomere Ends";"Meiotic synapsis";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Opening";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"DNA methylation"
XP_016982090.2	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_016984413.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842	"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II"
XP_016969892.2	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016987715.2	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_016982162.1	15	Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5467333	"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated"
XP_044317143.1	18	MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7205	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation"
XP_016986959.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016989010.1	3	MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_016971931.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_016979631.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6	"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism"
XP_044315069.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044315917.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_016990789.2	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_044316169.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_016977424.2	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016972136.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257	"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Degradation of DVL";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Neddylation";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN"
XP_016987258.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_016991267.1	12	Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-193692	"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR"
XP_016974581.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440	"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network"
XP_016983517.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-68877	"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Mitotic Prometaphase"
XP_016981597.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016986203.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016980283.2	5	Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630	"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3"
XP_016982790.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_016986922.1	8	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-438066	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_016972716.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_016985724.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_044313836.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_016970906.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_016973666.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044314873.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016975808.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016976975.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016984425.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016989730.2	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_044314187.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_016970267.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_016972697.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_016978801.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-110312	"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1"
XP_016987728.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016987553.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_016982811.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044314583.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016980679.2	5	MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661	"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation"
XP_016981033.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016986859.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016983052.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016982542.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Ion channel transport"
XP_016982435.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_044312818.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_044315539.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016984702.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_016974960.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation"
XP_016991347.1	7	MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586	"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_016984385.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016981039.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016974392.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044313492.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_044316483.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016972600.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_016972077.2	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016978040.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016982288.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016983982.2	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016970212.2	14	KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055	"Sphingolipid metabolism";"Synthesis of PE";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Synthesis of PC";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_016979939.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016985825.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885	"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins"
XP_016986041.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016982572.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation"
XP_044312977.1	13	Reactome: R-HSA-4341670;Reactome: R-HSA-2206308;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation";"Galactose metabolism";"Sphingolipid metabolism";"Sialic acid metabolism";"Keratan sulfate degradation";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_016990537.1	15	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_044312808.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016978084.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044316609.1	19	Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484	"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Chylomicron assembly";"VLDL assembly";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"VLDL clearance";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"LDL remodeling";"Scavenging by Class F Receptors"
XP_044316795.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016971144.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016984518.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016977471.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044315819.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_016979740.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_044314115.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_016980351.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016975972.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044317960.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_016977024.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016991146.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044315354.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016969638.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016977233.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_016980611.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016973600.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016971785.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_044314650.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_044314170.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044316510.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016983850.2	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016990360.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016983367.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_016978620.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016983083.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016975405.2	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_016987568.2	12	KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-1861;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171	"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis"
XP_016971625.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016985496.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016985857.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC"
XP_044312476.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016989475.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044312939.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016970758.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016987050.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016986914.2	10	Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_016988567.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_016989349.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation"
XP_016974168.2	3	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016983069.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-8931987;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;Reactome: R-HSA-9018519;Reactome: R-HSA-75109;MetaCyc: PWY-5667;Reactome: R-HSA-2426168;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166	"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"RUNX1 regulates estrogen receptor mediated transcription";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Estrogen-dependent gene expression";"Triglyceride biosynthesis";"CDP-diacylglycerol biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_016975859.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016973980.1	9	MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-8086	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_016990861.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016976170.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_044313529.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016968920.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016991262.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016973704.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016985387.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016973418.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_016983673.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016983071.2	16	Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813	"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids"
XP_044316798.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016990702.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_016984473.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_044315544.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016984884.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016982569.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016991268.1	11	Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756	"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Ub-specific processing proteases";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_016983871.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_016976503.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-983168	"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977825.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016981877.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016971852.1	7	MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;MetaCyc: PWY-46;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-31	"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Putrescine biosynthesis III";"Urea cycle";"Arginine and proline metabolism";"Urea cycle";"Canavanine degradation"
XP_016986535.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016981932.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016978590.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_044316203.1	3	Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60	"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation"
XP_016971646.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044314358.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016970699.1	3	Reactome: R-HSA-6807505;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016981041.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_016985225.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_016985411.1	14	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167238	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation"
XP_016987374.1	6	Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13	"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"G alpha (z) signalling events";"Phosphatidylinositol signaling system"
XP_016972762.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription"
XP_016986227.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016977591.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016985003.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016987096.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5873	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
XP_044316012.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016980672.2	5	Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661	"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation"
XP_044317319.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_044315068.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016968871.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events"
XP_016988859.2	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016989452.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016969184.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016974975.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016982815.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016985728.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016972299.1	56	Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport"
XP_016973338.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_044316880.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016973673.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_044314258.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016991256.2	10	MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;KEGG: 00710+2.7.2.3	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms"
XP_044314545.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044313142.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_016982087.2	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_016974816.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016984687.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016979404.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044314336.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016991452.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016970771.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016991272.1	10	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-917729	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_016976788.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_016987678.1	10	MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;Reactome: R-HSA-69205;MetaCyc: PWY-7198;MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7210;KEGG: 00670+2.1.1.45	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"One carbon pool by folate"
XP_016971356.2	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_016981372.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016986998.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_016990249.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016985410.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-113418	"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex"
XP_016978945.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016988393.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_044313421.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016984718.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016983520.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_044317316.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_016985820.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_016988077.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_044317358.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597	"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events"
XP_016984727.1	11	Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862	"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_044317824.1	10	KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Galactose metabolism";"Sphingolipid metabolism";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_016971484.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016974593.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_016977593.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016991801.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_016983323.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044315541.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016969965.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044313794.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-210744	"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_016987922.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016973778.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_044314444.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_044317335.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_044314916.1	42	Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-3214815;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-977225;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-212300	"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"DNA methylation";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Packaging Of Telomere Ends";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged purine";"Meiotic recombination";"Amyloid fiber formation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA"
XP_016990350.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016977706.2	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016987671.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73933	"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)"
XP_016976858.2	19	Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480	"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"LDL remodeling";"Scavenging by Class F Receptors";"Chylomicron clearance";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"Chylomicron assembly";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"VLDL clearance";"Scavenging by Class A Receptors"
XP_016988755.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_016977069.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_044315133.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_016975998.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016985726.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016985282.1	19	MetaCyc: PWY-5537;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;MetaCyc: PWY-5172;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-6728;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5392	"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II"
XP_016970548.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016973807.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016980730.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062	"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis"
XP_016984680.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016974032.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016982100.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044317228.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_016969001.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016989847.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events"
XP_016982702.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574	"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Propanoyl-coa degradation II"
XP_016972331.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016981696.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_044313099.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211945	"Endogenous sterols";"Xenobiotics";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds"
XP_044314330.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016992300.2	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_016992143.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_044314440.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_016984724.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-176407	"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_044314809.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
XP_016979303.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_016985856.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_016971996.1	4	Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583	"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_016974397.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016983736.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_016969065.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016976797.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_044317794.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_044313396.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016977070.2	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044317483.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016981464.2	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016981198.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_044313795.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-201722;Reactome: R-HSA-1234158;Reactome: R-HSA-933541;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082	"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression"
XP_016989370.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016984159.2	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_044315810.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016978302.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_016972288.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_016976610.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016980286.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044314753.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_016978610.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_016976331.2	29	KEGG: 00982+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-6333;MetaCyc: PWY-5057;MetaCyc: PWY-6342;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-5082;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-3162;MetaCyc: PWY-7111;MetaCyc: PWY-7013;MetaCyc: PWY-5751;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-7118;MetaCyc: PWY-6871;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6313;KEGG: 00350+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-6802	"Drug metabolism - cytochrome P450";"Glycine, serine and threonine metabolism";"L-leucine degradation III";"Naphthalene degradation";"Pyruvate fermentation to ethanol I";"Acetaldehyde biosynthesis I";"L-valine degradation II";"Noradrenaline and adrenaline degradation";"Retinol metabolism";"L-phenylalanine degradation III";"L-methionine degradation III";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol II";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to isobutanol (engineered)";"(S)-propane-1,2-diol degradation";"Phenylethanol biosynthesis";"Fatty acid degradation";"Butanol and isobutanol biosynthesis (engineered)";"Chitin degradation to ethanol";"3-methylbutanol biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Serotonin degradation";"Tyrosine metabolism";"Metabolism of xenobiotics by cytochrome P450";"L-isoleucine degradation II";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol III";"Salidroside biosynthesis"
XP_016984073.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016979824.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016991107.2	17	MetaCyc: PWY-5695;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-6627	"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Purine salvage";"Guanine and guanosine salvage";"Salinosporamide A biosynthesis"
XP_016974802.2	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_044314891.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_016975950.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_016991067.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016989336.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016972960.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016984359.1	7	KEGG: 00550+2.7.8.13;MetaCyc: PWY-6471;MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-5265;Reactome: R-HSA-4549356;KEGG: 00510+2.7.8.15	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"N-Glycan biosynthesis"
XP_016985360.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)"
XP_016991030.2	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016979222.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_016980044.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016991468.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1"
XP_016972164.2	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_016972704.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167287	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery"
XP_016970776.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016980662.1	7	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-8856828	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis"
XP_016969702.2	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016985897.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016986713.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016980333.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016991177.1	8	Reactome: R-HSA-163754;MetaCyc: PWY-5723;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;Reactome: R-HSA-8950505	"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_016979206.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016969120.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016973644.2	11	Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8862803;Reactome: R-HSA-6796648;Reactome: R-HSA-450341;Reactome: R-HSA-2559582;Reactome: R-HSA-2871796	"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of the AP-1 family of transcription factors";"Senescence-Associated Secretory Phenotype (SASP)";"FCERI mediated MAPK activation"
XP_044317527.1	14	KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4	"Linoleic acid metabolism";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_016989325.1	12	MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5871	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_016969719.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_016983994.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40	"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_016980183.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_016985763.1	7	KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263	"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis"
XP_044315980.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977473.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044315645.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016985993.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_016982844.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_016977600.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016989662.2	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016985108.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780	"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome"
XP_044316864.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016989841.2	9	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection"
XP_016982592.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_016985175.1	6	KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166;MetaCyc: PWY-7817;MetaCyc: PWY-5668;MetaCyc: PWY-5269;Reactome: R-HSA-1483148	"Glycerophospholipid metabolism";"Synthesis of PA";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Synthesis of PG"
XP_016987935.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_016983738.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_016975433.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016979288.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016968955.2	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_016977845.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_016985166.2	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_044316438.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016989854.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880	"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases"
XP_016971922.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-7900	"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_016969070.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016973679.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016975505.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_044316310.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397	"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Polymerase switching";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_016987189.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016981651.1	20	Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5693607	"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Polymerase switching";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends"
XP_016975938.1	10	KEGG: 00510+2.4.1.83;MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7661;Reactome: R-HSA-913709;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"N-Glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_016991167.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016970255.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_016973738.1	8	MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34	"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis"
XP_044316434.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_016990934.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016979122.2	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016973979.1	9	KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-196780;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1	"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes"
XP_016981191.2	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016972855.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016969683.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016978770.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537	"Regulation of MECP2 expression and activity";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_016978514.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_016976848.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016969684.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982508.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016973961.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016985261.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_016981784.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016971492.2	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016980665.2	5	Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661	"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation"
XP_016984129.2	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_016971482.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044316258.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_016986904.2	12	Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932	"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Synaptic adhesion-like molecules"
XP_016988810.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016991108.1	17	Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-6627	"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Purine salvage";"Guanine and guanosine salvage";"Salinosporamide A biosynthesis"
XP_016987227.2	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_016988886.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_044312931.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016981704.2	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016974305.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016980580.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016983859.1	13	KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation"
XP_016972689.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016991533.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016978430.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_044316533.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364	"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_016986627.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_016974674.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_016969635.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016979655.1	16	Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017	"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6"
XP_016968889.1	6	Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-7391	"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)"
XP_016969630.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016975973.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016984069.2	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_016983580.1	24	Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-418555	"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"G-protein activation";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G alpha (s) signalling events"
XP_016973150.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044313806.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_016982297.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016983598.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016985994.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_016991563.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016982286.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016986131.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016975440.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016988482.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016991492.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis"
XP_016985075.2	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016990278.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016982558.2	21	MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7184	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_016987714.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016980824.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016978806.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016974506.2	17	Reactome: R-HSA-202424;Reactome: R-HSA-975163;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-168638;Reactome: R-HSA-450321	"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_016982618.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016990723.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_044316782.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016971283.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044314789.1	2	Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_016973722.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_044315395.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016979045.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016986828.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_044317057.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"TBC/RABGAPs";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_016982727.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_044317959.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_016988736.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016973672.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_016977096.2	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016987228.2	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_016975115.2	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_016984460.2	32	Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167158	"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex"
XP_016990863.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016973967.2	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016979771.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_016983439.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_016979412.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593	"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity"
XP_016989581.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_016991261.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016987828.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016975949.2	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_016977610.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016986300.2	7	Reactome: R-HSA-9018676;Reactome: R-HSA-9023661;Reactome: R-HSA-9020265;Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-9018896;Reactome: R-HSA-6798695	"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of E-series 18(S)-resolvins";"Neutrophil degranulation"
XP_016983709.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016970534.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_016987134.1	7	MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_016983004.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016991223.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_016978038.2	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_044315358.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016977114.1	7	Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation"
XP_044316544.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway"
XP_016990264.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016989107.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_044316872.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044316783.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016989768.2	7	Reactome: R-HSA-1483148;MetaCyc: PWY-3561;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166	"Synthesis of PG";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_016984681.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016972200.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_016984598.2	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_016977590.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016988114.2	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016988564.1	26	Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression"
XP_016971106.1	12	Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4	"Transport and synthesis of PAPS";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Selenocompound metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Purine metabolism"
XP_044314694.1	6	MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1	"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_016988174.2	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_044317927.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016986589.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016969633.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016980134.1	19	Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-936837	"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases"
XP_044317348.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016985209.1	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_016979992.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044314254.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016979361.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016970974.2	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_016981795.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016990346.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044316354.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_044312472.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-983168;Reactome: R-HSA-8866427	"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation"
XP_016970570.2	5	Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_044312399.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016988390.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016971150.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016973798.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_016990626.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_016971846.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5689880	"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ub-specific processing proteases"
XP_016987664.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-5989;Reactome: R-HSA-163765;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-6282;MetaCyc: PWY-7663;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-5366;MetaCyc: PWY-5994;MetaCyc: PWY-5973	"Fatty acid biosynthesis";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Stearate biosynthesis II (bacteria and plants)";"ChREBP activates metabolic gene expression";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis"
XP_016979787.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_044316899.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044312848.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_016979133.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_044315838.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_044312874.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing"
XP_016972006.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination"
XP_044314329.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016988176.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_044317345.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016979989.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_044316420.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_044316789.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_044314852.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044313316.1	5	Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_016979187.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_016990171.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_016978609.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_016971835.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_016968992.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016988768.2	6	Reactome: R-HSA-76005;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-416993	"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors"
XP_044316261.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016976873.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979629.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_044317921.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016983533.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016986317.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016976985.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_044314030.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_016971109.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016988392.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_016978886.2	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_044314123.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-202733	"HS-GAG degradation";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall"
XP_016974503.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016990198.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_016988280.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016986386.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016977834.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_016986973.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044313160.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016986967.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport"
XP_044314323.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016975081.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_016982877.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_016979262.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016985127.1	8	MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ATP biosynthesis";"Photosynthesis";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_044317524.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016969685.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016983710.2	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_016972066.2	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_044314517.1	5	Reactome: R-HSA-75896;MetaCyc: PWY-7782;Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241	"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Peroxisomal protein import"
XP_016979252.2	10	Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-200425	"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Carnitine metabolism"
XP_016982734.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588	"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_044315352.1	25	Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-381771;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-392170	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"G-protein activation";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12"
XP_016981950.2	14	Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-193692	"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR"
XP_044316894.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044316651.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016987107.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016989644.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_016969777.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016985873.1	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-6545	"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_016984817.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016975542.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016990331.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016981048.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016973765.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_016975697.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016982823.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016983123.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_016970543.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016991759.2	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_016982991.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016974371.1	7	Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381183	"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Platelet degranulation";"PERK regulates gene expression";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_016977560.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016970618.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_016973029.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016973670.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_016987443.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_044316805.1	5	Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_044313072.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044314902.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_016986418.1	9	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_016989749.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016972923.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination"
XP_016984690.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_044312419.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044315080.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044316889.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016989763.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_044314408.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_016980319.1	6	MetaCyc: PWY-7356;MetaCyc: PWY-6908;Reactome: R-HSA-196819;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907	"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)"
XP_016973641.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016989168.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_016981596.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044316127.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
XP_016992225.2	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_044312923.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_016970560.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016978019.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044316755.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016985783.1	2	Reactome: R-HSA-216083;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"ECM proteoglycans"
XP_016986963.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016983243.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_016989545.2	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016973685.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Cristae formation";"Regulation of HSF1-mediated heat shock response"
XP_016983488.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016981921.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-437239	"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Mitotic Prometaphase";"Recycling pathway of L1"
XP_044317351.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_016973120.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_044315361.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_044315311.1	44	Reactome: R-HSA-5663213;Reactome: R-HSA-6802952;Reactome: R-HSA-5668599;Reactome: R-HSA-5654732;Reactome: R-HSA-8943724;Reactome: R-HSA-5674499;Reactome: R-HSA-2559580;Reactome: R-HSA-881907;Reactome: R-HSA-6802955;Reactome: R-HSA-8940973;Reactome: R-HSA-982772;Reactome: R-HSA-74749;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-5654727;Reactome: R-HSA-2559585;Reactome: R-HSA-8939211;Reactome: R-HSA-444257;Reactome: R-HSA-9635465;Reactome: R-HSA-170968;Reactome: R-HSA-2559582;Reactome: R-HSA-879415;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-5654733;Reactome: R-HSA-6802946;Reactome: R-HSA-450341;Reactome: R-HSA-198753;Reactome: R-HSA-5654726;Reactome: R-HSA-112409;Reactome: R-HSA-445144;Reactome: R-HSA-2871796;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-3371453;Reactome: R-HSA-6802948;Reactome: R-HSA-6811558;Reactome: R-HSA-456926;Reactome: R-HSA-2029482;Reactome: R-HSA-5675221;Reactome: R-HSA-202670;Reactome: R-HSA-1295596;Reactome: R-HSA-162658	"RHO GTPases Activate WASPs and WAVEs";"Signaling by BRAF and RAF fusions";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR3 signaling";"Regulation of PTEN gene transcription";"Negative feedback regulation of MAPK pathway";"Oxidative Stress Induced Senescence";"Gastrin-CREB signalling pathway via PKC and MAPK";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RUNX2 regulates osteoblast differentiation";"Growth hormone receptor signaling";"Signal attenuation";"mTOR signaling pathway";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Negative regulation of FGFR2 signaling";"Oncogene Induced Senescence";"ESR-mediated signaling";"RSK activation";"Suppression of apoptosis";"Frs2-mediated activation";"Senescence-Associated Secretory Phenotype (SASP)";"Advanced glycosylation endproduct receptor signaling";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Negative regulation of FGFR4 signaling";"Signaling by moderate kinase activity BRAF mutants";"Activation of the AP-1 family of transcription factors";"ERK/MAPK targets";"Negative regulation of FGFR1 signaling";"RAF-independent MAPK1/3 activation";"Signal transduction by L1";"FCERI mediated MAPK activation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"Regulation of HSF1-mediated heat shock response";"Signaling by high-kinase activity BRAF mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of MAPK pathway";"ERKs are inactivated";"Spry regulation of FGF signaling";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_016981077.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044313939.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_016973169.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016985442.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016973799.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016984346.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_044315359.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_044312644.1	2	KEGG: 00514+2.4.1.222;Reactome: R-HSA-1912420	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in Golgi"
XP_016989066.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_016987163.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_044317356.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_016990969.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016987524.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_016971237.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016974091.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_044313830.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_016982674.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_016970813.2	7	MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7790;Reactome: R-HSA-500753	"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis"
XP_016983964.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016974246.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016983203.2	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_016974764.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_044313978.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_016970535.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016987370.1	6	Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13	"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"G alpha (z) signalling events";"Phosphatidylinositol signaling system"
XP_016985550.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016981694.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_016990663.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_044316826.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_044313409.1	24	Reactome: R-HSA-5218920;Reactome: R-HSA-5625740;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-444257;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;KEGG: 04926+2.7.11.1	"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs";"GPVI-mediated activation cascade";"Thermogenesis";"CD28 dependent PI3K/Akt signaling";"RSK activation";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"Relaxin signaling pathway"
XP_016984682.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016970975.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044312822.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_044313793.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_016975380.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044314892.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_016974446.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_044312847.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_016972677.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016976434.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016984160.2	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_044316671.1	10	KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism"
XP_016991299.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_016987591.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016981881.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977481.1	14	MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417	"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)"
XP_016977938.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016988110.2	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_016974890.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016984946.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA modification in the mitochondrion";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_016969030.1	7	Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456	"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"Folate biosynthesis";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Phenylketonuria"
XP_016968979.2	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016971082.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC"
XP_016990784.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_016981105.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016977613.1	4	KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14	"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism"
XP_016971186.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684	"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Neddylation";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state"
XP_016991478.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_044315581.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_016982472.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016985107.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_016992279.1	26	Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-1445148	"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Gap junction assembly";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016987372.1	6	Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-1250196	"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling"
XP_044316251.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_044317114.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_016984686.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016992277.1	19	MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-7383	"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_016972367.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_044316807.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3	"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism"
XP_016978840.2	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_044317930.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016981392.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis"
XP_016985068.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979416.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016974159.1	18	MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7222	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_016984450.1	8	Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_044314704.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016981032.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016979254.2	10	Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354	"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy"
XP_016981180.1	11	Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"p38MAPK events";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_016985425.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016991837.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016978813.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_044315114.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752	"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated"
XP_016977883.1	5	KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22	"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism"
XP_016971196.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_044317250.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044317565.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_016979713.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-3371571	"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"HSF1-dependent transactivation"
XP_016985469.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016988758.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_016987112.1	29	Reactome: R-HSA-174437;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-3371511;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135	"Removal of the Flap Intermediate from the C-strand";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HSF1 activation";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Dual incision in TC-NER"
XP_016980254.1	12	Reactome: R-HSA-75893;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"TNF signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Growth hormone receptor signaling";"Collagen degradation";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_044312411.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016973261.1	12	Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-76071	"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_044314489.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016979497.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_016980174.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946	"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants"
XP_016976676.1	6	KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403	"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)"
XP_016973902.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016970214.2	14	Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055	"Synthesis of PE";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Ether lipid metabolism";"Synthesis of PC";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_044315290.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_016977136.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044317219.1	9	KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00401+2.6.1.5	"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Tyrosine catabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Novobiocin biosynthesis"
XP_016988783.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016978376.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016985474.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_016985201.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_044315097.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5467348	"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex"
XP_016972692.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016984306.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_016976883.1	19	Reactome: R-HSA-8876725;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-3214858;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Protein methylation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"RMTs methylate histone arginines";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016990528.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_044313429.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016974766.2	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016991248.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825	"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis"
XP_044313992.1	8	KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_016977595.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016985453.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016988108.2	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_044317128.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982497.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_016979016.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network"
XP_016990468.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016979188.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_016984893.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_044314997.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016974957.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016986993.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_016984997.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044314769.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_044314342.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897	"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carnitine metabolism";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes"
XP_016968982.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016977562.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_016985213.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_044314947.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016982359.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977475.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016989645.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_044314608.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016979994.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016971462.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_016969959.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016986771.1	17	Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9645460;Reactome: R-HSA-975163;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-445989	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_016989177.2	11	Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-5696397	"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_016979342.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016991647.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_016990258.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016986561.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016986715.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016986999.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_016986873.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_044312422.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016988588.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016990197.2	3	Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3108214	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins"
XP_016984994.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044315312.1	44	Reactome: R-HSA-6802948;Reactome: R-HSA-6811558;Reactome: R-HSA-456926;Reactome: R-HSA-202670;Reactome: R-HSA-5675221;Reactome: R-HSA-2029482;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-3371453;Reactome: R-HSA-162658;Reactome: R-HSA-1295596;Reactome: R-HSA-879415;Reactome: R-HSA-6802946;Reactome: R-HSA-5654726;Reactome: R-HSA-198753;Reactome: R-HSA-450341;Reactome: R-HSA-445144;Reactome: R-HSA-112409;Reactome: R-HSA-2871796;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-5654733;Reactome: R-HSA-375165;Reactome: R-HSA-2559585;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-444257;Reactome: R-HSA-170968;Reactome: R-HSA-9635465;Reactome: R-HSA-2559582;Reactome: R-HSA-8939211;Reactome: R-HSA-5674499;Reactome: R-HSA-2559580;Reactome: R-HSA-6802952;Reactome: R-HSA-5663213;Reactome: R-HSA-5668599;Reactome: R-HSA-5654732;Reactome: R-HSA-8943724;Reactome: R-HSA-8940973;Reactome: R-HSA-6802955;Reactome: R-HSA-982772;KEGG: 04150+2.7.11.24;Reactome: R-HSA-74749;Reactome: R-HSA-881907	"Signaling by high-kinase activity BRAF mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"ERKs are inactivated";"Negative regulation of MAPK pathway";"Regulation of actin dynamics for phagocytic cup formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"Regulation of HSF1-mediated heat shock response";"Golgi Cisternae Pericentriolar Stack Reorganization";"Spry regulation of FGF signaling";"Advanced glycosylation endproduct receptor signaling";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR1 signaling";"ERK/MAPK targets";"Activation of the AP-1 family of transcription factors";"Signal transduction by L1";"RAF-independent MAPK1/3 activation";"FCERI mediated MAPK activation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Negative regulation of FGFR4 signaling";"NCAM signaling for neurite out-growth";"Oncogene Induced Senescence";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"RSK activation";"Frs2-mediated activation";"Suppression of apoptosis";"Senescence-Associated Secretory Phenotype (SASP)";"ESR-mediated signaling";"Negative feedback regulation of MAPK pathway";"Oxidative Stress Induced Senescence";"Signaling by BRAF and RAF fusions";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR3 signaling";"Regulation of PTEN gene transcription";"RUNX2 regulates osteoblast differentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Growth hormone receptor signaling";"mTOR signaling pathway";"Signal attenuation";"Gastrin-CREB signalling pathway via PKC and MAPK"
XP_016982350.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016989233.2	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_016990649.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016987377.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044313889.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016980557.2	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016990339.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016973513.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016981781.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_044314360.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016984293.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044316936.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016990045.2	9	Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin"
XP_044315065.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016974882.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_044317269.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016968869.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_044314413.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016970334.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016979668.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044313251.1	4	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Neurotransmitter clearance"
XP_016989646.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_016981911.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_016969722.1	8	KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;Reactome: R-HSA-5683826	"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine salvage";"Surfactant metabolism"
XP_016981066.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016972422.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_016971026.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_044317804.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016975932.2	10	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_044313545.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016984995.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016982439.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_044314701.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016980719.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2	"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway"
XP_044316518.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016980829.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016972416.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_044312421.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016973014.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_016991971.2	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016970472.2	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016985076.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016980806.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_044315753.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Macroautophagy";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_016986318.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_044317317.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_016982089.2	6	KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_016980917.1	14	KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-75896;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-5667;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.42	"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Peroxisomal protein import";"Glycerophospholipid metabolism"
XP_016986085.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016980616.2	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_016980501.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016975564.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016982019.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_016979758.1	29	Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-6782135	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Dual incision in TC-NER"
XP_044314333.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016975705.1	11	MetaCyc: PWY-5659;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-882;MetaCyc: PWY-3881;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7456	"GDP-mannose biosynthesis";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation"
XP_016988103.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016973270.2	13	Reactome: R-HSA-186797;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-1442490	"Signaling by PDGF";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Extracellular matrix organization";"ECM proteoglycans";"NCAM1 interactions";"Collagen degradation"
XP_016985679.1	15	Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659	"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"Interleukin-7 signaling";"RET signaling"
XP_016972684.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_044314021.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_016986861.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016986554.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016986838.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_044315424.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016971865.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016979830.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016989286.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_016980343.1	4	MetaCyc: PWY-5874;Reactome: R-HSA-189483;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18	"Heme degradation I";"Heme degradation";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism"
XP_044315631.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_044316048.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_044314328.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016970789.1	14	Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-69273;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-2467813	"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Separation of Sister Chromatids"
XP_016988804.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016989675.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_044316877.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016980669.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016986287.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531	"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus"
XP_016976032.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_016985695.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_016976716.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_016973934.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016970770.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016975557.2	29	Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693548;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-69541;Reactome: R-HSA-5693565;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-6804756;Reactome: R-HSA-349425;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-6803204;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"mTOR signaling pathway";"HDR through Single Strand Annealing (SSA)";"Human cytomegalovirus infection";"Sensing of DNA Double Strand Breaks";"Human papillomavirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Stabilization of p53";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Phosphorylation";"Autodegradation of the E3 ubiquitin ligase COP1";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Degradation";"Relaxin signaling pathway"
XP_016985729.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044312797.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016976859.1	24	Reactome: R-HSA-164378;Reactome: R-HSA-5610783;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;Reactome: R-HSA-8963896;Reactome: R-HSA-5610785;Reactome: R-HSA-163358;Reactome: R-HSA-381676;Reactome: R-HSA-8853659;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5621575;Reactome: R-HSA-432040;Reactome: R-HSA-392517;Reactome: R-HSA-5610780;Reactome: R-HSA-9634600;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163560;Reactome: R-HSA-180024;Reactome: R-HSA-111931;Reactome: R-HSA-422356;Reactome: R-HSA-5687128;Reactome: R-HSA-5610787;Reactome: R-HSA-9010642	"PKA activation in glucagon signalling";"Degradation of GLI2 by the proteasome";"PKA activation";"VEGFA-VEGFR2 Pathway";"HDL assembly";"GLI3 is processed to GLI3R by the proteasome";"PKA-mediated phosphorylation of key metabolic factors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"RET signaling";"mTOR signaling pathway";"CD209 (DC-SIGN) signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Rap1 signalling";"Degradation of GLI1 by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Triglyceride catabolism";"DARPP-32 events";"PKA-mediated phosphorylation of CREB";"Regulation of insulin secretion";"MAPK6/MAPK4 signaling";"Hedgehog 'off' state";"ROBO receptors bind AKAP5"
XP_044316528.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_016986689.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_044313944.1	5	Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_044312826.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_044312936.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016973502.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016971266.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016976509.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016968859.1	12	MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Gluconeogenesis";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis"
XP_044314458.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_016990864.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016982179.1	3	Reactome: R-HSA-5083635;Reactome: R-HSA-189085;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins"
XP_016969368.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-182218;Reactome: R-HSA-9636467	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification"
XP_016979413.2	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_016990782.2	33	Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-4085377	"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins"
XP_044313397.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016988395.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016990709.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016990673.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044314032.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016990329.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016986905.2	12	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_016989442.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_016980711.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_016989846.1	13	Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52	"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_016981502.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016973954.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016976160.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_016971780.2	13	Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-381676	"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_016989631.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016981043.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016973381.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016977609.2	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_016979031.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_016986845.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016987131.2	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_016983526.1	6	Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7395;MetaCyc: PWY-7077;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25	"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_016983174.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016988478.1	13	Reactome: R-HSA-5687128;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476	"MAPK6/MAPK4 signaling";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"EPHB-mediated forward signaling";"NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Thermogenesis";"G alpha (12/13) signalling events";"Human papillomavirus infection";"G alpha (q) signalling events"
XP_016974644.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016984294.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016984641.1	6	MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_044313143.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_044312957.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_016973938.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016991032.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016981076.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016975158.2	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_016983398.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016988481.1	13	KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-3928662;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Rho GTPase cycle";"mTOR signaling pathway";"NRAGE signals death through JNK";"EPHB-mediated forward signaling";"Human cytomegalovirus infection";"MAPK6/MAPK4 signaling";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_016983519.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy"
XP_016974751.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044314326.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016979995.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016982864.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016982456.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016970433.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016980118.1	9	Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6351	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_016983581.1	24	Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315	"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK"
XP_016978624.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656	"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"MET receptor recycling"
XP_016990939.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016990643.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016982302.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_016984643.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016981386.2	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_016984138.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016984265.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016984245.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016973640.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_016981088.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_016987386.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016990450.1	30	Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-2564830;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-6782135	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Dual incision in TC-NER"
XP_016975694.2	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_044314407.1	42	Reactome: R-HSA-73728;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-2299718;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-110331;Reactome: R-HSA-912446	"RNA Polymerase I Promoter Opening";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"DNA methylation";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Late Events";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Condensation of Prophase Chromosomes";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Cleavage of the damaged purine";"Meiotic recombination"
XP_016981257.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016982117.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016981981.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016980154.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016969939.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016982728.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport"
XP_016984207.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_016985960.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016972403.1	17	Reactome: R-HSA-167200;Reactome: R-HSA-75955;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167287;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167238;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Th1 and Th2 cell differentiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"T cell receptor signaling pathway";"Pausing and recovery of HIV elongation"
XP_016985416.2	20	MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7007	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)"
XP_016976722.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016974210.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016979367.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_016975693.2	26	Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-389977;Reactome: R-HSA-5617833	"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Post-chaperonin tubulin folding pathway";"Cilium Assembly"
XP_016983422.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_016990025.1	6	KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6606	"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II"
XP_016975087.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_016973676.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_044316013.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016991781.2	4	Reactome: R-HSA-5696394;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_016984447.2	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016976789.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016969949.1	10	KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-6174	"Terpenoid backbone biosynthesis";"Butanoate metabolism";"PPARA activates gene expression";"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)"
XP_016973199.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_016971163.2	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_044314151.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016979987.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-1169408	"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"ISG15 antiviral mechanism"
XP_016986130.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044314318.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_016974971.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016980106.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016983140.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_016974771.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044316148.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044316901.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016988345.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016987769.1	7	Reactome: R-HSA-77288;KEGG: 00071+1.3.8.7;MetaCyc: PWY-7094;Reactome: R-HSA-77348;Reactome: R-HSA-77346;Reactome: R-HSA-1989781;KEGG: 00280+1.3.8.7	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid degradation";"Fatty acid salvage";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"PPARA activates gene expression";"Valine, leucine and isoleucine degradation"
XP_016979870.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_016982594.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016971294.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016991374.2	9	Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation"
XP_016976285.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
XP_016978949.2	6	Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation"
XP_044313073.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016984982.2	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_016982035.2	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016991428.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_016984166.2	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_016981074.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016971176.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016973937.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016973340.1	4	Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_016982457.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044315854.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016975146.1	10	MetaCyc: PWY-6535;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19;KEGG: 00640+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19	"4-aminobutanoate degradation I";"4-aminobutanoate degradation V";"beta-Alanine metabolism";"Propanoate metabolism";"Degradation of GABA";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"Butanoate metabolism"
XP_016990124.1	7	KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22	"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_016984342.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016970017.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016982459.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016973058.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180910	"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"HCMV Late Events";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs"
XP_016981923.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_044316309.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044316921.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016979395.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016985482.2	30	Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-2644606;Reactome: R-HSA-5676590;Reactome: R-HSA-2644607;Reactome: R-HSA-917937;Reactome: R-HSA-68949	"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Prolactin receptor signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"Circadian Clock";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Iron uptake and transport";"Orc1 removal from chromatin"
XP_044314202.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016977049.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016972420.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044313069.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_044316403.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_044313852.1	17	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6608;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-7179;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Purine salvage";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation"
XP_016978555.2	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation"
XP_016988235.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_016981949.2	14	Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-9017802	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"Noncanonical activation of NOTCH3"
XP_044317186.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_016969276.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex"
XP_016980362.2	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016973326.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016992207.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_044312930.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016989350.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_016979283.2	19	MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6920;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-5136	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_016983780.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_044314940.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016972682.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_016979344.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016981708.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016983900.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_016971649.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35	"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_016982328.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016974208.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016978370.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044316065.1	42	Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-977225;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-9610379;Reactome: R-HSA-69473;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-73728	"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"Cleavage of the damaged purine";"Amyloid fiber formation";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Late Events";"G2/M DNA damage checkpoint";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"DNA methylation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Packaging Of Telomere Ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening"
XP_044316751.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_016986379.2	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016985495.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016979168.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane"
XP_016982546.1	18	Reactome: R-HSA-5674404;MetaCyc: PWY-6368;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-5689896;KEGG: 00562+3.1.3.67;KEGG: 04070+3.1.3.67;Reactome: R-HSA-8986944;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5628897;Reactome: R-HSA-199418;Reactome: R-HSA-8943723;KEGG: 05235+3.1.3.16	"PTEN Loss of Function in Cancer";"3-phosphoinositide degradation";"Ub-specific processing proteases";"Regulation of PTEN localization";"Ovarian tumor domain proteases";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Transcriptional Regulation by MECP2";"Th1 and Th2 cell differentiation";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"T cell receptor signaling pathway";"TP53 Regulates Metabolic Genes";"Negative regulation of the PI3K/AKT network";"Regulation of PTEN mRNA translation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016977668.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016986901.2	12	Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982	"Synaptic adhesion-like molecules";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_016991537.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis"
XP_016974825.2	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_016969679.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_016972203.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_016984507.1	7	KEGG: 00230+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184	"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_016980124.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-399719	"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Trafficking of AMPA receptors"
XP_016973373.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_016990935.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016983995.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_016971729.2	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016972466.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_016981844.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_016974460.2	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016979287.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016975481.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016982187.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016973905.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016970265.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_016989132.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016978059.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016986830.1	10	MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-5826	"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis"
XP_016989885.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_044312765.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016982018.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_016985104.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016974515.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_016990062.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016974375.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756	"Neutrophil degranulation";"Synthesis of PC";"WNT mediated activation of DVL";"Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation"
XP_016971141.1	8	Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472	"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_016972278.2	10	Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459	"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_016970891.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044312594.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016983068.1	14	MetaCyc: PWY-8055;Reactome: R-HSA-8931987;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;Reactome: R-HSA-2426168;MetaCyc: PWY-8051;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;Reactome: R-HSA-9018519;Reactome: R-HSA-75109	"Palmitoyl ethanolamide biosynthesis";"RUNX1 regulates estrogen receptor mediated transcription";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Activation of gene expression by SREBF (SREBP)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Estrogen-dependent gene expression";"Triglyceride biosynthesis"
XP_016980716.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4"
XP_016986736.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016970286.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016985402.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_044317315.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_016987369.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_016988034.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016972913.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_016981045.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016990716.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016986719.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016978484.1	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
XP_044317542.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016974367.1	4	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_016986528.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016975327.2	10	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6807505	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes"
XP_044317081.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016969522.2	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_016983380.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_044316441.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_016982174.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016989075.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_044317535.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016976628.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016981181.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_016985828.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_016989056.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016980387.2	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_016980217.2	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_044313762.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016976565.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_044317552.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016974049.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery"
XP_044314460.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_016981652.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_044315620.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016981274.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_016972366.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016983304.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016985443.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016970451.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016981226.1	5	Reactome: R-HSA-162710;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"Synthesis of glycosylphosphatidylinositol (GPI)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_016973219.1	58	Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5689901;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-382556	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Metalloprotease DUBs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Ub-specific processing proteases";"ABC-family proteins mediated transport"
XP_016989991.2	32	Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-72203	"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA"
XP_016990233.2	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_044317254.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016978441.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_016979238.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_044316792.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016977484.2	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_016989771.2	7	Reactome: R-HSA-1483148;MetaCyc: PWY-3561;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166	"Synthesis of PG";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_016981216.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016980792.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016974755.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_044316828.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016984249.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016980565.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016975088.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_016980194.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_016987090.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016987607.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_016982896.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_016975586.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_044314116.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_016969383.1	56	Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978	"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_016989256.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_044316237.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016990242.1	17	Reactome: R-HSA-68877;Reactome: R-HSA-174178;Reactome: R-HSA-9022692;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;KEGG: 05170+2.7.11.1;Reactome: R-HSA-141444;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1	"Mitotic Prometaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of MECP2 expression and activity";"Thermogenesis";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Human cytomegalovirus infection";"mTOR signaling pathway";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Human immunodeficiency virus 1 infection";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Human papillomavirus infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway"
XP_016989240.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_016976253.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990670.1	6	Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442;MetaCyc: PWY-6983	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis"
XP_016988992.1	29	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER"
XP_016969974.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016971958.2	4	Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis"
XP_016989773.2	6	Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway"
XP_016971461.1	17	MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744	"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Candicidin biosynthesis";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Glyoxylate assimilation"
XP_016981593.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016990942.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016972919.1	13	MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)"
XP_016986898.2	12	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_016983624.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016984796.1	5	MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis"
XP_044317511.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_044313101.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-8937144	"Xenobiotics";"Endogenous sterols";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling"
XP_016973583.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016991562.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016985485.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_044312515.1	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases"
XP_016972064.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_044317984.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_016991015.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016988483.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016980579.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016980500.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016981402.2	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress"
XP_016987375.1	6	Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13	"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system"
XP_016971345.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_016989866.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016978641.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_044313102.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-211945	"PPARA activates gene expression";"Xenobiotics";"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds"
XP_044316898.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016973942.1	5	KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-7766	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_016986995.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016973269.1	13	MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Purine catabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism"
XP_016974001.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016982732.1	9	KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;MetaCyc: PWY-5265;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016985717.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016981089.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_016972592.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_044315155.1	10	KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153	"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"mTOR signaling pathway";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection"
XP_016980517.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016992002.2	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_016981564.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016972683.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_044315881.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_016977204.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016971279.1	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_016968828.2	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
XP_044313346.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016982013.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174	"Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_044316122.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_016990250.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016979048.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_016989580.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_016977351.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016974048.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_016981999.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_044312647.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979144.2	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_016990215.2	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_016991799.1	7	KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234	"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III"
XP_016971102.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016973457.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_044313732.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_016973826.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_044313557.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016983893.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_016977840.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016985312.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_016980542.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_044314897.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016985226.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016975286.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_016972134.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_044316932.1	3	Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation"
XP_016984741.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016990454.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_044316524.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_016972423.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016973434.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-2173789	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"UCH proteinases";"Iron uptake and transport";"TGF-beta receptor signaling activates SMADs"
XP_016980648.2	10	MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-6372	"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_016971103.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016971844.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128	"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling"
XP_016971165.2	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_016986834.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016979285.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016983420.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044312905.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016985006.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016971753.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation"
XP_016979822.1	18	MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227	"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_016971726.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_016991780.2	4	Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_016971394.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016982862.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016976506.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_016978778.1	3	KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_016986354.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016975626.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044314594.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016968990.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016973742.1	56	Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323	"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling"
XP_016985105.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016976971.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_016986136.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_044316830.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016975203.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_016978503.2	7	KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation"
XP_016969416.2	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_016987086.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016989548.2	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016969372.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111463	"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs"
XP_016982530.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016976514.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016970799.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712	"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling"
XP_016990928.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016972604.1	17	Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-174411	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere"
XP_044316008.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016983763.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_016986810.1	7	MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11	"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Inositol phosphate metabolism"
XP_016983212.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination"
XP_016977493.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_016973768.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016972040.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_016979663.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_016979301.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044317474.1	9	Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation"
XP_016988521.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016986088.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination"
XP_016985894.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016978525.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_016973076.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_016980833.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016980490.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016989605.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016973598.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_044316235.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_016980769.1	7	Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-212300	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"HCMV Early Events";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA"
XP_044316904.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_044313427.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016970313.1	6	Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_016971032.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_016981697.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016975387.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-72764	"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Methylation";"Eukaryotic Translation Termination"
XP_016973147.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016969646.1	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_016981571.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016979167.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane"
XP_044315062.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016983133.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_016971203.1	25	Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-437239	"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Gap junction assembly";"Mitotic Prometaphase";"Recycling pathway of L1"
XP_016986513.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016987422.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016980581.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016970462.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016983543.2	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_016974880.2	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_016977342.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016979696.1	42	KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7094;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7007;MetaCyc: PWY-6945;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7778;MetaCyc: PWY-5177;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-1361;MetaCyc: PWY-6435;MetaCyc: PWY-5789;MetaCyc: PWY-6944;MetaCyc: PWY-6946;MetaCyc: PWY-6863;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-5138;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00410+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7779;MetaCyc: PWY-6883;KEGG: 00627+4.2.1.17	"Fatty acid degradation";"Benzoate degradation";"Butanoate metabolism";"Fatty acid elongation";"Toluene degradation";"alpha-Linolenic acid metabolism";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Fermentation to 2-methylbutanoate";"Fatty acid salvage";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Caprolactam degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Geraniol degradation";"Pyruvate fermentation to butanol I";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"2-methylpropene degradation";"Glutaryl-coa degradation";"Propanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoyl-coa degradation I (aerobic)";"4-hydroxybenzoate biosynthesis III (plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Androstenedione degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to hexanol (engineered)";"Phenylalanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"beta-Alanine metabolism";"Limonene and pinene degradation";"Spodoptera littoralis pheromone biosynthesis";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol II (engineered)";"Aminobenzoate degradation"
XP_016982393.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044314700.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016991933.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016983802.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016969268.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016973964.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_044314341.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756	"Macroautophagy";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation"
XP_016986747.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016985739.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_016986886.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016977907.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_016986571.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016980171.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016971884.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016975602.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016969674.2	9	Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_016976847.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016979265.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_044314850.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016977809.2	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016980492.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016968965.1	12	KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-1187;MetaCyc: PWY-7901;MetaCyc: PWY-601;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-6936	"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)"
XP_016973827.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_016984594.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016970407.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016973025.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_044316064.1	42	Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-5578749;Reactome: R-HSA-2559582;Reactome: R-HSA-73728;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-3214842;Reactome: R-HSA-212300;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924	"DNA methylation";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"Transcriptional regulation by small RNAs";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Opening";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Meiotic synapsis";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Cleavage of the damaged purine";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"HDMs demethylate histones";"PRC2 methylates histones and DNA";"G2/M DNA damage checkpoint";"HCMV Late Events";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression"
XP_016984299.2	6	MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_016980013.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_016990930.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016977533.2	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016989971.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_016989062.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_044314024.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_016980233.1	8	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)"
XP_044312408.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016984407.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_016980827.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_044315458.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_016986127.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016990885.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001	"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism"
XP_016975707.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016979610.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_016990730.2	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016983954.2	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016990680.2	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_016979365.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
XP_044315028.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016987001.1	5	MetaCyc: PWY-7919;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7918	"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)"
XP_016978132.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016977313.2	15	Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939	"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)"
XP_044312761.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_044315067.1	18	Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4	"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism"
XP_016971232.2	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_016971441.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_016973617.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_044316870.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016981245.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_044317588.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016980160.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_016972952.2	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016985058.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_016978601.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7574	"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II"
XP_016973127.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_044313162.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_044314919.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I"
XP_016990656.2	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016987780.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_016989138.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122	"G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016975181.2	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_044312968.1	5	MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism"
XP_016984251.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016981695.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_016969943.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_016984418.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016987075.2	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_016986186.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_016972015.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_016989330.1	5	Reactome: R-HSA-193048;Reactome: R-HSA-446199;Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129	"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_044313116.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016970760.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016991809.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_044316701.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016974209.2	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016989549.2	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_016986718.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044315821.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_016981875.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_016977962.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016976974.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016976767.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"ATP biosynthesis";"Photosynthesis"
XP_016983088.1	24	Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276	"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Mitotic Prometaphase";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_016972827.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016975635.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_044315916.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_016986765.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016971164.2	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016982401.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016974354.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016986573.2	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016973079.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016987707.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016989094.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_016991797.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis"
XP_044316961.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016982797.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_044313163.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016983582.1	24	Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G-protein activation";"G alpha (i) signalling events"
XP_044317031.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016975537.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016975888.2	7	Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Phytate degradation I"
XP_016972274.2	10	Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-983231	"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production"
XP_016986047.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016981783.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016972419.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_044317263.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016988766.2	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_016990518.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_016989935.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974	"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway"
XP_016983993.1	15	MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383	"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Rubisco shunt";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_016978812.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_044314190.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_016973632.1	13	Reactome: R-HSA-3371511;Reactome: R-HSA-8876725;Reactome: R-HSA-110320;Reactome: R-HSA-6798695;Reactome: R-HSA-532668;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877	"HSF1 activation";"Protein methylation";"Translesion Synthesis by POLH";"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs"
XP_016989362.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016971177.1	19	MetaCyc: PWY-7115;Reactome: R-HSA-70263;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-5913	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)"
XP_016977645.2	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_016990485.2	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_016979112.1	3	Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism"
XP_016970674.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016971755.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_016992231.1	2	KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate"
XP_016985136.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016972659.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016986817.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_016987508.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016980559.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_016987582.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_016968954.2	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_016986878.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016968918.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016986996.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016984706.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_016990536.1	9	MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-6901	"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation"
XP_016975961.1	8	Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885	"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins"
XP_016975809.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016986690.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_016972900.1	12	MetaCyc: PWY-5857;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5855	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_016973149.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016981129.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1362300	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_016983564.1	5	Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665	"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells"
XP_016969705.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016990293.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016977979.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-195253	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex"
XP_016989274.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016985412.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_016976623.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_044316862.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016985427.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016971983.1	6	MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_044312807.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_016984027.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016981957.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016983208.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016974562.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_016975669.2	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_016990756.1	7	MetaCyc: PWY-6737;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6724;MetaCyc: PWY-7238	"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation II";"Sucrose biosynthesis II"
XP_016979409.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-426486	"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis"
XP_016979343.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016977597.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016986046.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016977472.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016976019.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_016990523.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016977365.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016979408.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700	"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_016979368.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912	"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_016980742.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_016989671.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187	"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress"
XP_016970540.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_044316236.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_016983030.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113	"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Neddylation";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1"
XP_016982397.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016977596.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016988548.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_016987018.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_016982188.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016970735.2	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016979903.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016980634.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016981295.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events"
XP_016969056.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016976161.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_016983070.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016976880.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016975889.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_016979734.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016986206.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016982142.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016972004.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016984414.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione degradation (DUG pathway"
XP_016976744.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016982296.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_044315989.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016974796.2	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016981891.1	10	MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5497;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-3841	"L-histidine degradation III";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)"
XP_016971153.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016972433.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016978642.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_044316774.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_016985653.2	4	Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_016976300.2	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_044316891.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016985221.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_044316421.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016971647.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016986053.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016969999.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016973589.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_016981505.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_044312518.1	4	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_016980585.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016980590.2	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_016970777.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016971520.1	8	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by Hippo";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_016990868.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016985716.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016986560.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016985359.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_016973699.1	10	KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484	"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_016976973.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016983706.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016984652.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_016972188.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_016969087.2	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_016975979.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_016975534.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016975258.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016971842.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_016980223.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_016983799.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044317142.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016988236.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787	"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state"
XP_016984417.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016977207.2	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016980176.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_016978028.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016984437.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016985797.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-8873719	"Intra-Golgi traffic";"RAB geranylgeranylation"
XP_016974128.2	10	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_016978060.2	8	KEGG: 00710+5.3.1.6;Reactome: R-HSA-71336;Reactome: R-HSA-5659996;MetaCyc: PWY-5723;KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461;KEGG: 00051+5.3.1.6;MetaCyc: PWY-1861	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Rubisco shunt";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_016984913.1	7	MetaCyc: PWY-7255;MetaCyc: PWY-8043;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_016969073.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016980159.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244	"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation"
XP_044317523.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016981466.2	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016980807.1	4	MetaCyc: PWY-7250;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis"
XP_016981982.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_016988746.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016987137.1	5	MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-5523	"Roseoflavin biosynthesis";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)"
XP_016970495.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_044314412.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_044314203.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016983513.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
XP_044312909.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016971768.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016973192.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016974369.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-381033	"IRE1alpha activates chaperones";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones"
XP_044316220.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016987636.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016980588.2	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016983782.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_016984951.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_016979325.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_016982495.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016981038.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016981452.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-171007	"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"p38MAPK events"
XP_016969748.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_044314185.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_016989050.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_044313140.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-7036	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II"
XP_044317321.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_016989083.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_044315440.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016970478.2	3	Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_016986762.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016983085.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016990068.2	3	KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation"
XP_016982751.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport"
XP_016979570.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016982571.2	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016978171.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_016986552.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_044314796.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_044317379.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_016969912.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_016975834.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_016981424.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_044313853.1	17	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6608;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-7179;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Purine salvage";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation"
XP_016970840.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_016985947.2	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_016986725.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016984993.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_044317590.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_016985078.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016976418.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016983599.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_016979617.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016983545.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016988408.1	7	KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3	"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism"
XP_044316773.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016987451.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016988498.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_016974728.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_016975074.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER"
XP_016988183.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_044317064.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_044314428.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_016985791.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_016980287.2	10	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_016989185.2	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016984835.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016981454.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_016972382.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016974179.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_044316878.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016979907.1	10	KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;MetaCyc: PWY-5890;MetaCyc: PWY-5844;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5895;MetaCyc: PWY-5839	"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis"
XP_016988885.1	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016973720.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_044315630.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_044317833.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016973588.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_044313592.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_016983960.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_016984499.2	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016986907.2	12	Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_016989085.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_044313677.1	16	Reactome: R-HSA-2219530;Reactome: R-HSA-1963640;Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-1251985;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-1250342;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-1250347;Reactome: R-HSA-8847993	"Constitutive Signaling by Aberrant PI3K in Cancer";"GRB2 events in ERBB2 signaling";"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"Nuclear signaling by ERBB4";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"SHC1 events in ERBB4 signaling";"ERBB2 Activates PTK6 Signaling"
XP_016971870.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_044317221.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016979014.1	3	Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60	"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation"
XP_016979266.2	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_016987173.2	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_016981645.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_016972369.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016973618.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016972914.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport"
XP_016986005.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_016981040.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016973863.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016977835.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_016976449.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_016969563.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_044315830.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_016975711.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016983743.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_016988013.1	42	Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-5250924;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-1912408;Reactome: R-HSA-73772;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-73728;Reactome: R-HSA-5625886;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-8936459	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"Amyloid fiber formation";"Cleavage of the damaged purine";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"B-WICH complex positively regulates rRNA expression";"G2/M DNA damage checkpoint";"HCMV Late Events";"Estrogen-dependent gene expression";"DNA methylation";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Escape";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_016979080.2	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_016979381.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016968919.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016983783.2	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016986872.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016974041.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_016981846.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_016979704.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_016987027.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5678895;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174154	"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of DVL";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Defective CFTR causes cystic fibrosis";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin"
XP_016971650.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_016982705.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016982795.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_016987823.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016987631.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_016989794.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_044312843.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_016983158.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016983373.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_044315739.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_016988195.1	18	Reactome: R-HSA-167290;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167200	"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_016984386.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016971152.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016983807.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_016986559.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_044314405.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016972669.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016974628.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_016969068.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_044316744.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016990941.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016986778.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168325	"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis"
XP_016987822.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016976417.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016981959.1	4	KEGG: 00513+3.2.1.114;MetaCyc: PWY-7920;KEGG: 00510+3.2.1.114;MetaCyc: PWY-7426	"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_016987180.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016972896.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016982701.2	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_016971023.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_016987523.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016987703.1	4	MetaCyc: PWY-6281;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis"
XP_016975083.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_016969746.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_016981326.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016991497.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016972567.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination"
XP_016981443.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis"
XP_016984333.1	33	Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-69202;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-69656;Reactome: R-HSA-8939236;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin A:Cdk2-associated events at S phase entry";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_044312546.1	3	Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Ub-specific processing proteases"
XP_016978548.2	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_016975090.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_016977605.2	18	MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7115;MetaCyc: PWY-1622	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)"
XP_016985734.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_044314961.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_016986920.1	8	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation"
XP_044317901.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016980431.2	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301	"Streptomycin biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis"
XP_016984113.2	4	Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;MetaCyc: PWY-5188	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_016973467.2	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016982555.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016982283.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016985706.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016968887.2	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events"
XP_016983742.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_016970557.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016976887.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_016969870.2	5	KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3841	"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I";"Folate transformations II (plants)"
XP_044317245.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016984772.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016988599.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_016974917.1	6	MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067	"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_016990633.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016983393.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_044315538.1	3	KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_016988411.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016972236.2	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016973404.2	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_016982622.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016987936.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_016983171.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA"
XP_016978530.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome"
XP_016973372.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016975706.1	11	MetaCyc: PWY-7456;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;MetaCyc: PWY-3881;MetaCyc: PWY-6992;MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-5659	"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Mannitol biosynthesis";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"GDP-mannose biosynthesis"
XP_016981809.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016970026.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_016972103.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016991219.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016973634.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-442720	"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_016982612.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_044312720.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016979828.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016987637.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_044314152.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016969716.2	8	Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900	"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4"
XP_016986899.2	12	Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-399719	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Trafficking of AMPA receptors"
XP_016985191.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016990256.1	14	MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-3781;MetaCyc: PWY-4302;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1	"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Oxidative phosphorylation"
XP_016975710.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016980666.1	7	Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7836	"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis"
XP_016990522.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016989282.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016976597.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport"
XP_016978728.1	15	Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-176409	"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_016971831.2	15	Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression"
XP_016991100.2	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_016973965.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016980181.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016987512.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016987247.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_044317077.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016980661.1	7	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation"
XP_016969258.1	5	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_016990028.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_016981744.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016984735.2	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016981599.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_044313361.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016972133.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_016975061.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_044315004.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_016986566.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922	"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_016987827.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016977547.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_044312441.1	13	Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-9645460	"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway"