Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_015428818.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_015438391.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_015438213.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_015432589.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015432197.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015430758.1 6 Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_015437438.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015431201.1 5 MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_015429659.1 20 Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616 "Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_015437969.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_015430288.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_015437004.1 20 MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7858 "10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"Fatty acid degradation";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II" XP_015432214.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_015428549.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015428934.1 22 MetaCyc: PWY-7602;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7035;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7606;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-6598 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis" XP_015435041.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_015432260.1 13 Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490 "Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Extracellular matrix organization";"NCAM1 interactions";"Integrin cell surface interactions";"Anchoring fibril formation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Collagen degradation" XP_015438342.1 7 Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-31 "Urea cycle";"Arginine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation" XP_015430894.1 3 Reactome: R-HSA-5083635;Reactome: R-HSA-189085;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"Digestion of dietary carbohydrate";"O-glycosylation of TSR domain-containing proteins" XP_015439210.1 1 Reactome: R-HSA-419771 "Opsins" XP_015437202.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015437872.1 15 MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901 "Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation" XP_015437413.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_015432585.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015429456.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015434546.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_015431228.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Tryptophan metabolism" XP_015432612.1 4 MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism" XP_015436738.1 12 Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7385;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13 "Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism" XP_015433680.1 7 Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-114608 "IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"Platelet degranulation" XP_015436984.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015435909.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922 "Activation of SMO";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium" XP_015431004.1 3 Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627 "O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6" XP_015432051.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015433737.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015437755.1 5 Reactome: R-HSA-3232118;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571 "SUMOylation of transcription factors";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)" XP_015434483.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015431369.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015431376.1 56 Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236 "Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_015430142.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_015429391.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015430376.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015436576.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_015429571.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015432152.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015438534.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_015435279.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015438204.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_015435146.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015430570.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_015438529.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_015439796.1 37 Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-983170;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-2132295;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-204005;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-5578749 "Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"MHC class II antigen presentation";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"COPII-mediated vesicle transport";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs" XP_015431182.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015429209.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015433476.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015433325.1 12 MetaCyc: PWY-6683;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4 "Assimilatory sulfate reduction III";"Selenate reduction";"Sulfate activation for sulfonation";"Selenocompound metabolism";"Sulfite oxidation III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Purine metabolism";"Sulfur metabolism";"Purine metabolism" XP_015432751.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_015434802.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015429722.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015432599.1 4 MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26 "Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" XP_015430866.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_015429707.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_015432644.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015431088.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_015430336.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_015430469.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015439377.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)" XP_015434312.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015434565.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015436415.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015438076.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015438716.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis" XP_015428986.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015438900.1 8 KEGG: 00950+1.14.16.2;MetaCyc: PWY-3581;Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-5049;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133 "Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis I";"Catecholamine biosynthesis";"Tyrosine metabolism";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"Folate biosynthesis";"(S)-reticuline biosynthesis II" XP_015433077.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015439072.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_015429665.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_015434674.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_015431324.1 3 Reactome: R-HSA-114608;Reactome: R-HSA-195399;Reactome: R-HSA-194313 "Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization";"VEGF ligand-receptor interactions" XP_015436877.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015431517.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015433681.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;MetaCyc: PWY-5189 "Neutrophil degranulation";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)" XP_015437349.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015438287.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation" XP_015431494.1 7 Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-375276;Reactome: R-HSA-140837 "G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"G alpha (i) signalling events";"Platelet degranulation";"Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation" XP_015428889.1 5 KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism" XP_015435891.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_015434082.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015437666.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_015439408.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015429481.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_015435529.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015432895.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015439025.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_015430159.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015436532.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015436723.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015435711.1 7 MetaCyc: PWY-2301;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25 "Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism" XP_015434384.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_015433365.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015434489.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015435788.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015434672.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_015432212.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_015436585.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_015430737.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015428772.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015434614.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015437282.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015439728.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events" XP_015437766.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-195253 "Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex" XP_015439256.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_015430757.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs" XP_015437014.1 12 KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5132;MetaCyc: PWY-7118;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133 "Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"L-isoleucine biosynthesis V";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Colupulone and cohumulone biosynthesis" XP_015430745.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_015434542.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015436539.1 33 Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-165054 "Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA" XP_015429595.1 10 Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-9648895;Reactome: R-HSA-156827;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-72702 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition" XP_015434091.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_015436786.1 34 Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-69656;Reactome: R-HSA-8939236;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-69202;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-69231 "RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin A:Cdk2-associated events at S phase entry";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"Cyclin E associated events during G1/S transition";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"Cyclin D associated events in G1" XP_015434660.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol" XP_015431726.1 7 Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-8950505;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015436892.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015435394.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015436163.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_015434916.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_015436634.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015437986.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_015433384.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015430930.1 5 Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants" XP_015428655.1 2 MetaCyc: PWY-8061;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins" XP_015432978.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015431133.1 4 KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817 "Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_015433049.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015434089.1 18 KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4 "Linoleic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" XP_015439859.1 6 Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_015440376.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_015430761.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_015430313.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015429688.1 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015437590.1 7 MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204 "2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" XP_015436501.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015429204.1 15 Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-111465 "Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins" XP_015429404.1 3 MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456 "Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid" XP_015439396.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_015433993.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015437017.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015439663.1 4 Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_015431177.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015439436.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_015431146.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex" XP_015435948.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015433885.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015439637.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_015438490.1 19 MetaCyc: PWY-7210;MetaCyc: PWY-7197;Reactome: R-HSA-380270;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7184;Reactome: R-HSA-380320;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_015437259.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015433882.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015438512.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_015434507.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_015432485.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015440001.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015438878.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_015433814.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_015429913.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_015433642.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Synthesis of PC" XP_015432329.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015439744.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway" XP_015436702.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015439088.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis" XP_015437350.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015434998.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015434094.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_015438028.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168 "ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)" XP_015435192.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015440333.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167242 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_015434164.1 19 Reactome: R-HSA-71403;MetaCyc: PWY-5537;Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-5690;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5538;Reactome: R-HSA-75105;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5 "Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Fatty acyl-CoA biosynthesis";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes" XP_015438322.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015429322.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_015434917.1 8 KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis" XP_015438080.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015430631.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015438696.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_015435127.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015437141.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_015429236.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_015435224.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015438328.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_015435732.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_015434122.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829 "Aggrephagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy" XP_015431838.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015433367.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015430705.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-380320 "Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Recycling pathway of L1";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes" XP_015437982.1 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" XP_015430848.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015435294.1 19 Reactome: R-HSA-5663213;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-5625970;Reactome: R-HSA-5627123;Reactome: R-HSA-5663220 "RHO GTPases Activate WASPs and WAVEs";"CD28 dependent Vav1 pathway";"EGFR downregulation";"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Rho GTPase cycle";"EPHB-mediated forward signaling";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate KTN1";"RHO GTPases activate PAKs";"RHO GTPases Activate Formins" XP_015429019.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015434893.1 3 Reactome: R-HSA-727802;Reactome: R-HSA-5619078;Reactome: R-HSA-6787639 "Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis" XP_015430092.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_015437661.1 10 MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-7328;MetaCyc: PWY-6527;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2 "D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism" XP_015436762.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_015439096.1 56 Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-174178 "Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015428577.1 13 KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Purine catabolism" XP_015430674.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015434289.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015431222.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015438383.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015433029.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015435208.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015440305.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015436149.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015431090.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015438973.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_015438456.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015430766.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015438725.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-420029;Reactome: R-HSA-2173791 "Asymmetric localization of PCP proteins";"Tight junction interactions";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" XP_015434199.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_015431650.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015434285.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015432878.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015430604.1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_015433306.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_015429363.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism" XP_015432867.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-69273 "RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Cyclin A/B1/B2 associated events during G2/M transition" XP_015434791.1 5 KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937 "Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Iron uptake and transport" XP_015429051.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_015432274.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015437908.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015439423.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015430989.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695 "Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation" XP_015432657.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015438388.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015435231.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015433980.1 4 MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1 "UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism" XP_015433152.1 1 Reactome: R-HSA-419771 "Opsins" XP_015430860.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015435839.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015438831.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_015433215.1 26 Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-389960 "Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"Cilium Assembly";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC" XP_015431879.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015439081.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015432681.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_015435393.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015436739.1 4 KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801 "Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion" XP_015432057.1 10 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-1912408 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation" XP_015433027.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015432801.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015434856.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015439268.1 6 KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020 "Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import" XP_015440021.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_015428754.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_015432677.1 7 KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517 "Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid" XP_015438514.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7417 "Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)" XP_015437780.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_015434527.1 16 MetaCyc: PWY-5749;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.4 "Itaconate degradation";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism" XP_015434084.1 12 KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-7901;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6842;MetaCyc: PWY-1187 "Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine" XP_015438450.1 7 Reactome: R-HSA-174403;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;MetaCyc: PWY-8043 "Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis" XP_015433385.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015434243.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015440049.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015439628.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015435196.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015433911.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015430079.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015435626.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015429333.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015431382.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015439522.1 9 MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-112043 "Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events" XP_015431555.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_015437330.1 18 Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7416 "Acyl chain remodelling of PC";"Synthesis of PA";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_015433390.1 5 MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159 "Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_015439631.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015430233.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015439898.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane" XP_015438590.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" XP_015429838.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_015436710.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_015438992.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015430418.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015428860.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-68952 "Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation" XP_015431791.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex" XP_015433459.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497 "ESR-mediated signaling";"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_015430263.1 14 MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_015430451.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015437695.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_015434725.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015438232.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015438071.1 7 KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_015435914.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_015438472.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015434680.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_015431138.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus" XP_015434965.1 4 Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118 "PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation" XP_015437815.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_015439391.1 7 Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798 "Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell" XP_015437435.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification" XP_015433366.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_015435381.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015432527.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_015433180.1 18 MetaCyc: PWY-7383;MetaCyc: PWY-6642;MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Tyrosine metabolism";"Arginine biosynthesis";"Phenylalanine metabolism";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis" XP_015431835.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015440175.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015438628.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015435447.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_015431667.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015429725.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_015430310.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015435459.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015437700.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_015440265.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_015433304.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_015435858.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis" XP_015430294.1 40 Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-5601884;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-76042 "HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_015434180.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015437432.1 4 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism" XP_015433381.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015438642.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_015432228.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_015432940.1 3 KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17 "Purine metabolism";"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism" XP_015435147.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015433751.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015438033.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015438873.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015431576.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015434829.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling" XP_015434425.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_015430744.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_015434251.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_015434931.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015430675.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015434476.1 6 Reactome: R-HSA-2046105;Reactome: R-HSA-9603798;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-390247;Reactome: R-HSA-2046106 "Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids";"alpha-linolenic acid (ALA) metabolism" XP_015433967.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015434088.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_015433973.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015436424.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation" XP_015434227.1 12 Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015431392.1 32 Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167152 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat" XP_015432259.1 3 KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" XP_015429249.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_015430741.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015432682.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015440266.1 18 Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015430579.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015430779.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015436245.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_015435768.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_015432063.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex" XP_015431744.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015429449.1 5 MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6 "Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism" XP_015433824.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015432242.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015432480.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_015431860.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-76042 "Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_015430970.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_015439407.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_015436360.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_015436555.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015433634.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015437819.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_015438530.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_015437160.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-5578749 "Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs" XP_015438597.1 14 Reactome: R-HSA-75109;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055 "Triglyceride biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PC";"Sphingolipid metabolism";"Synthesis of PE";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_015430657.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015436301.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015439712.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;MetaCyc: PWY-3722 "Glycine, serine and threonine metabolism";"Choline catabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)" XP_015430328.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_015434860.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_015430603.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015439906.1 56 Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764 "TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling" XP_015438645.1 25 Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-380270;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813 "MHC class II antigen presentation";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Kinesins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Cilium Assembly";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids" XP_015430216.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015430443.1 5 MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95;KEGG: 00680+1.1.1.95;KEGG: 00260+1.1.1.95;Reactome: R-HSA-977347 "L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" XP_015439179.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_015437253.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015429468.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_015430997.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015429948.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015435404.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015429770.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690 "SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Early Events" XP_015433785.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_015433170.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_015437094.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_015439216.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_015434783.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015439371.1 4 MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" XP_015432777.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_015430622.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015431035.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015435440.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015435289.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_015439293.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015435084.1 5 Reactome: R-HSA-9609523;Reactome: R-HSA-6811438;Reactome: R-HSA-5694530;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Intra-Golgi traffic";"Cargo concentration in the ER";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_015433407.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends" XP_015440379.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_015432960.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_015438837.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015431274.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015438915.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015436959.1 12 Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-674695 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events" XP_015437153.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_015430149.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763 "Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction" XP_015433431.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015435220.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_015439250.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015435273.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015431059.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015437450.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015431207.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_015432614.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015431258.1 8 Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580 "HCMV Early Events";"Regulation of PTEN gene transcription";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence" XP_015432939.1 6 Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-6527 "Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Stachyose degradation" XP_015438546.1 5 MetaCyc: PWY-6168;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26 "Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Riboflavin metabolism" XP_015439669.1 4 MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12 "Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_015436192.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_015440182.1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221 "T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway" XP_015430291.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_015431685.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_015440429.1 1 Reactome: R-HSA-156581 "Methylation" XP_015431637.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015430785.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015435193.1 6 MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;Reactome: R-HSA-191273 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis" XP_015439752.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015438523.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation" XP_015428632.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015439160.1 9 MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822 "Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_015429361.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015439087.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015430912.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_015430910.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_015440057.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_015434736.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015436928.1 7 MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-71336 "Chitin degradation I (archaea)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Pentose phosphate pathway" XP_015431198.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015432273.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-182218 "Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation" XP_015436726.1 5 Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857 "MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation" XP_015428955.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015428397.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_015430653.1 1 MetaCyc: PWY-6938 "NADH repair" XP_015432698.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015437741.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015431077.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015437773.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_015434648.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015429173.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015433338.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015428841.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_015432225.1 57 Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258 "MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL" XP_015428415.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015432360.1 57 Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258 "MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neutrophil degranulation";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL" XP_015434567.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015433717.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015428996.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_015429335.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015431630.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015436346.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_015431153.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_015436917.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-195253 "Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex" XP_015436393.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_015431478.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_015433038.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015429720.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015430751.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_015434909.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_015434932.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015432800.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015433033.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015435182.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015438022.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015438428.1 8 KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-241 "Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_015438835.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015433644.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-2514853 "Signal transduction by L1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes" XP_015433837.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015432595.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015431121.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015429865.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_015432989.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_015429079.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015439207.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015433558.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015429923.1 5 MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6 "Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism" XP_015433667.1 2 Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"Formation of apoptosome" XP_015438766.1 52 Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-73980;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-8851708;Reactome: R-HSA-76061;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-203927;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-75955 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"MicroRNA (miRNA) biogenesis";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Elongation" XP_015436193.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_015431731.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015432997.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015439339.1 11 Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2173796;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015431483.1 13 KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Thermogenesis";"mTOR signaling pathway";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015430525.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015429956.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_015429730.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174184 "ER-Phagosome pathway";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_015428564.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015430722.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015435425.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015436691.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_015440116.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015435295.1 19 Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-182971;Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-5625970;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-5627123;Reactome: R-HSA-5663220 "Myogenesis";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"EGFR downregulation";"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Rho GTPase cycle";"RHO GTPases activate KTN1";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"RHO GTPases activate PAKs";"RHO GTPases Activate Formins" XP_015429967.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015432444.1 6 Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-912446 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination" XP_015431560.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation" XP_015438430.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "mTOR signalling";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_015439655.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_015437369.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015438427.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_015437200.1 14 KEGG: 00290+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5078;MetaCyc: PWY-5057;MetaCyc: PWY-5104;MetaCyc: PWY-5101;KEGG: 00770+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5103;Reactome: R-HSA-70895;MetaCyc: PWY-5076;MetaCyc: PWY-5108 "Valine, leucine and isoleucine biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine degradation II";"L-valine degradation II";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis III";"Branched-chain amino acid catabolism";"L-leucine degradation III";"L-isoleucine biosynthesis V" XP_015433458.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_015440111.1 9 Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607 "HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends" XP_015433495.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_015428585.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015428403.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_015438774.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015430967.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015437644.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_015437878.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8053 "Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II" XP_015432385.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_015431625.1 8 Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-380972 "Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_015433321.1 7 KEGG: 00020+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61 "Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Lysine degradation";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_015435649.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_015439437.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015433538.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_015436013.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015439877.1 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_015431136.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_015430523.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_015430904.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_015434109.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015429432.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015431311.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_015437191.1 6 Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7395;MetaCyc: PWY-7077;KEGG: 00520+3.5.1.25 "Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism" XP_015429316.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_015435699.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015431357.1 11 Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-1268020;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-3299685 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Mitochondrial protein import";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species" XP_015433114.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015436827.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_015436878.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015440034.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015431091.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015435714.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015434845.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015435215.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015432413.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015433544.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015439967.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015436992.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015431195.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015430646.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015435248.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_015430170.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_015433258.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015434202.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_015439630.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015429537.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015432874.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015429871.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015437518.1 18 MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7221 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis" XP_015440123.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015436018.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015440345.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015431802.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_015430978.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_015437084.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_015429202.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_015439065.1 6 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" XP_015431185.1 7 KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263 "Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis" XP_015430790.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015438240.1 8 MetaCyc: PWY-7573;MetaCyc: PWY-66;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5739;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;Reactome: R-HSA-6787639 "GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" XP_015437737.1 5 Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_015433497.1 14 Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-1632852;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"Intraflagellar transport";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Macroautophagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic" XP_015431031.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015428472.1 19 Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423 "Chylomicron clearance";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Chylomicron remodeling";"VLDL clearance";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"VLDL assembly" XP_015436836.1 5 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" XP_015434200.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_015433836.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_015434330.1 5 MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;Reactome: R-HSA-9033241 "Plasmalogen biosynthesis";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import" XP_015440167.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015435437.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015433840.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015428816.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_015431294.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_015434572.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2426168 "Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)" XP_015433000.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015428724.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015432191.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015435359.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation" XP_015437882.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015437398.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015433903.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_015434816.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2 "Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione metabolism";"Taurine and hypotaurine metabolism" XP_015439665.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" XP_015436784.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015437825.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_015437400.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597 "Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events" XP_015433151.1 1 Reactome: R-HSA-419771 "Opsins" XP_015429068.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015437960.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_015433624.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015437762.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_015429447.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015429741.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_015435672.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015439894.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015430596.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_015430805.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-442982 "Regulation of MECP2 expression and activity";"RAF activation";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor" XP_015429022.1 30 Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-2564830;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Cytosolic iron-sulfur cluster assembly";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping" XP_015429067.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015433553.1 4 KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_015430325.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015432484.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015435674.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" XP_015435615.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015437265.1 10 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357956;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TNFR1 signaling";"Thermogenesis" XP_015432107.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919 "Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Anchoring fibril formation";"Crosslinking of collagen fibrils" XP_015437894.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015438130.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015435417.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015435337.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_015430948.1 24 Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-8964616;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-163359;Reactome: R-HSA-400042;Reactome: R-HSA-420092 "G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G beta:gamma signalling through CDC42";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon signaling in metabolic regulation";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors" XP_015430807.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000 "Interferon gamma signaling";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"RAF activation" XP_015436054.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015432430.1 6 MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-6922 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis" XP_015428914.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_015440496.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_015437491.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_015439855.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015436078.1 4 Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193 "Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_015429226.1 2 Reactome: R-HSA-69231;Reactome: R-HSA-8934593 "Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity" XP_015428907.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_015430048.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015433616.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015432720.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-3232142 "Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"SUMOylation of ubiquitinylation proteins" XP_015434857.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_015432203.1 3 KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615 "Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation" XP_015433934.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis" XP_015434708.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_015433802.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015439113.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015432265.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015431895.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_015435004.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_015439320.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176407 "APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_015434443.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466 "Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis" XP_015435513.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_015431719.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_015434855.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015430234.1 52 Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-8851708;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167242 "RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_015431866.1 7 Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015438903.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_015437323.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_015436321.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_015439086.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015431986.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_015436945.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015429295.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_015438351.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015434673.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi" XP_015438647.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015440505.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_015437535.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015430239.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015431359.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015435219.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015436008.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_015434333.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015434873.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015429368.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015429480.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Dual incision in TC-NER" XP_015434647.1 9 KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18 "Drug metabolism - other enzymes";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione metabolism" XP_015435152.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015436030.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015440314.1 2 Reactome: R-HSA-196299;Reactome: R-HSA-4641262 "Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_015432866.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-165054;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-69273;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-450520 "RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Cyclin A/B1/B2 associated events during G2/M transition";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA" XP_015433763.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-456926 "G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)" XP_015430086.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_015436486.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015430697.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_015430804.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-5576892 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Ion homeostasis";"RAF activation";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation" XP_015433233.1 9 MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7411;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8 "1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism" XP_015436338.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015437501.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015431951.1 5 Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994 "Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_015439373.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015433861.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015433776.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015430663.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015439415.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695 "Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Neutrophil degranulation" XP_015429691.1 4 MetaCyc: PWY-7849;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394;MetaCyc: PWY-5691 "Urate conversion to allantoin III";"Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin I" XP_015437230.1 7 KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14 "Drug metabolism - other enzymes";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism" XP_015439871.1 7 MetaCyc: PWY-7221;MetaCyc: PWY-6596;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;Reactome: R-HSA-6798695 "Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Inosine 5'-phosphate degradation";"Neutrophil degranulation" XP_015430193.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015435773.1 12 KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Signaling by FGFR1 in disease";"NRAGE signals death through JNK";"Human papillomavirus infection";"Human cytomegalovirus infection";"Rho GTPase cycle";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015434250.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway" XP_015432157.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_015435675.1 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_015430400.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015439764.1 4 MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32 "Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_015435862.1 9 Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809 "FCERI mediated MAPK activation";"Rho GTPase cycle";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization" XP_015431327.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_015428880.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015438289.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation" XP_015438882.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015431598.1 7 Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72706 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015437355.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015437929.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015436697.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015434549.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015429212.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015434787.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015431143.1 5 Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400 "AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"mTOR signalling";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer" XP_015432097.1 3 Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320 "Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH" XP_015429216.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_015439026.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Hedgehog 'on' state";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Neddylation";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL" XP_015435364.1 5 MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189 "2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)" XP_015437556.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_015428474.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_015435276.1 5 MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-6692 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation" XP_015430667.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015433056.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis" XP_015434076.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015432562.1 14 Reactome: R-HSA-71403;MetaCyc: PWY-4302;MetaCyc: PWY-7279;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1 "Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Butanoate metabolism" XP_015429942.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015438237.1 8 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_015430156.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015429052.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015432334.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_015436613.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-901042 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle" XP_015437399.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-5099900 "Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4" XP_015437587.1 6 MetaCyc: PWY-2941;MetaCyc: PWY-5097;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7;MetaCyc: PWY-8088 "L-lysine biosynthesis II";"L-lysine biosynthesis VI";"Lysine biosynthesis";"L-lysine biosynthesis III";"Monobactam biosynthesis";"Dipicolinate biosynthesis" XP_015439040.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_015438687.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_015431079.1 6 KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7346 "Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_015437738.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_015432167.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015432647.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015438591.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" XP_015439781.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_015437699.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_015435286.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_015433024.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015433953.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015429426.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015428734.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_015432164.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015428823.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_015433899.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_015439563.1 4 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism" XP_015440181.1 5 Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015437724.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_015437131.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015435430.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015435500.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015430334.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015432344.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_015433275.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015434125.1 52 Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-76061;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-5601884;Reactome: R-HSA-75955;Reactome: R-HSA-749476;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-167172 "RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome" XP_015440484.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015430386.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_015431657.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015430172.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015435118.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015438704.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015435297.1 8 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015439968.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015434841.1 11 Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253 "Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_015436790.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516 "Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin" XP_015435531.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015440320.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_015436560.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC" XP_015435114.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015439288.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015430249.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015436681.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_015430984.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015439969.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015433692.1 3 Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17 "Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis" XP_015432584.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015432081.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_015437931.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310 "HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Fanconi Anemia Pathway" XP_015429790.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015432545.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015434177.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015430947.1 24 Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-418592 "Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1" XP_015428732.1 13 Reactome: R-HSA-8866654;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-8876725;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5689896;Reactome: R-HSA-9646399;Reactome: R-HSA-110320 "E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein methylation";"Neutrophil degranulation";"HSF1 activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Ovarian tumor domain proteases";"Aggrephagy";"Translesion Synthesis by POLH" XP_015433881.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015434765.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015431518.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015428972.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015438104.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015430384.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_015429096.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1538133 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G0 and Early G1" XP_015432955.1 17 Reactome: R-HSA-6796648;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-674695;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-75955 "TP53 Regulates Transcription of DNA Repair Genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation" XP_015428837.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015437808.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015434445.1 17 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_015430792.1 5 Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473 "Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint" XP_015435397.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_015430949.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015436339.1 11 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6807878 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport" XP_015438393.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_015435371.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015428590.1 33 Reactome: R-HSA-8939236;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-69231;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167158 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"Cyclin D associated events in G1";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex" XP_015431159.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015438325.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_015437470.1 6 MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-1483166 "Glycerol degradation I";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Synthesis of PA" XP_015428700.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_015433811.1 3 Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807 "Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling" XP_015430693.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015436487.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015437936.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015437873.1 15 MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003 "Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol" XP_015432503.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_015429330.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015435321.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_015438263.1 4 Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255 "HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis" XP_015428953.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events" XP_015429402.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_015437409.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015434188.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015438846.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_015436825.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_015436838.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015433695.1 4 Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" XP_015438460.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015435769.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015429034.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015430453.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015435479.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015435453.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015429810.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015429170.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015430905.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_015428870.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015439786.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_015433252.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_015430155.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015435455.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015438010.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_015431902.1 11 MetaCyc: PWY-6174;MetaCyc: PWY-7524;KEGG: 00900+5.3.3.2;MetaCyc: PWY-922;MetaCyc: PWY-7102;MetaCyc: PWY-5123;Reactome: R-HSA-191273;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-7391 "Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Cholesterol biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Isoprene biosynthesis II (engineered)" XP_015437486.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015437981.1 11 Reactome: R-HSA-2029485;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053 "Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II" XP_015435342.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015429873.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_015434628.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015439610.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015436480.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_015431377.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015439518.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015436244.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" XP_015433908.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_015437716.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_015433025.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015436297.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_015437509.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015435680.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015430238.1 10 KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"HATs acetylate histones";"mTOR signaling pathway";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015435093.1 5 MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2 "Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis" XP_015429253.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015439977.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015429255.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_015440254.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015428398.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_015439357.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015437836.1 10 Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158 "Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system" XP_015430428.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_015438872.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_015440422.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015428595.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_015433866.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_015434412.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_015438281.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015438505.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_015431199.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015439447.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_015435696.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_015430047.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015436643.1 6 KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_015434544.1 2 Reactome: R-HSA-83936;Reactome: R-HSA-2564830 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Cytosolic iron-sulfur cluster assembly" XP_015428850.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015428789.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_015437508.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015432928.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_015429403.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_015431532.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_015429938.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_015439167.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015437804.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015433612.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295 "Neutrophil degranulation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation" XP_015432122.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_015435824.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015434471.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_015435802.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015437564.1 3 Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969 "Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina" XP_015438408.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015434450.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_015433917.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_015439579.1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237 "HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2" XP_015436713.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_015430211.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015438694.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015429877.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015440252.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_015435102.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558 "S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RAF activation";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_015440531.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_015438151.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015436280.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015431841.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-196108 "Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis" XP_015436925.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015436650.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_015430305.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015438257.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015433787.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_015432779.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015435434.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015439892.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_015438626.1 6 MetaCyc: PWY-6829;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;MetaCyc: PWY-7285 "Trna methylation (yeast)";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis" XP_015428461.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015429421.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_015428485.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015433711.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015432374.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015438055.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015438209.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_015437891.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015436259.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015439525.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015431955.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015435519.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_015436731.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_015435320.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_015436809.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_015431584.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_015438902.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_015438699.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_015428534.1 5 Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006 "Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_015439148.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702 "Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Neddylation";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Interleukin-1 signaling" XP_015440174.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015440291.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_015428575.1 13 MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7206;MetaCyc: PWY-6545;KEGG: 00240+3.6.1.9 "Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Purine catabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism" XP_015438848.1 3 Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4 "Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_015432428.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015428877.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015429987.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_015434057.1 10 Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579 "G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange" XP_015437260.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015432447.1 6 MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_015431666.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_015433774.1 57 Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex" XP_015437495.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015432697.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015435085.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015437333.1 18 Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417 "Acyl chain remodelling of PC";"Linoleic acid metabolism";"Synthesis of PA";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)" XP_015438600.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_015431709.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015437812.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015428893.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015429992.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015432023.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_015438103.1 42 Reactome: R-HSA-3214842;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-201722;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-212300;Reactome: R-HSA-73728;Reactome: R-HSA-110329;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-1221632;Reactome: R-HSA-5250924;Reactome: R-HSA-4551638;Reactome: R-HSA-1912408;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459 "HDMs demethylate histones";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Amyloid fiber formation";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"PRC2 methylates histones and DNA";"RNA Polymerase I Promoter Opening";"Cleavage of the damaged pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"Transcriptional regulation by small RNAs";"DNA methylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"Meiotic synapsis";"B-WICH complex positively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Pre-NOTCH Transcription and Translation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_015438373.1 9 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand" XP_015435533.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015430340.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015430679.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_015430102.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_015431597.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_015436460.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015432437.1 6 MetaCyc: PWY-6922;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-4981 "L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)" XP_015429138.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015434143.1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_015431178.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015429698.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015436122.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_015438697.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015436494.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015439366.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015437759.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_015433572.1 39 Reactome: R-HSA-5654687;Reactome: R-HSA-5654689;Reactome: R-HSA-5673001;Reactome: R-HSA-2033519;Reactome: R-HSA-5654693;Reactome: R-HSA-190373;Reactome: R-HSA-5654227;Reactome: R-HSA-8853338;Reactome: R-HSA-5654726;Reactome: R-HSA-5654720;Reactome: R-HSA-1839130;Reactome: R-HSA-2033514;Reactome: R-HSA-109704;Reactome: R-HSA-5654700;Reactome: R-HSA-6811558;Reactome: R-HSA-190375;Reactome: R-HSA-5654727;Reactome: R-HSA-5654695;Reactome: R-HSA-5654704;Reactome: R-HSA-190372;Reactome: R-HSA-5655253;Reactome: R-HSA-5654719;Reactome: R-HSA-5654228;Reactome: R-HSA-5654221;Reactome: R-HSA-5654712;Reactome: R-HSA-5654688;Reactome: R-HSA-5654699;Reactome: R-HSA-5654706;Reactome: R-HSA-1257604;Reactome: R-HSA-5655302;Reactome: R-HSA-2219530;Reactome: R-HSA-5654733;Reactome: R-HSA-1839122;Reactome: R-HSA-5654732;Reactome: R-HSA-190371;Reactome: R-HSA-5658623;Reactome: R-HSA-190322;Reactome: R-HSA-5654710;Reactome: R-HSA-5654219 "Downstream signaling of activated FGFR1";"PI-3K cascade:FGFR1";"RAF/MAP kinase cascade";"Activated point mutants of FGFR2";"FRS-mediated FGFR1 signaling";"FGFR1c ligand binding and activation";"Phospholipase C-mediated cascade, FGFR3";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR1 signaling";"PI-3K cascade:FGFR4";"Signaling by activated point mutants of FGFR3";"FGFR3 mutant receptor activation";"PI3K Cascade";"FRS-mediated FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FGFR2c ligand binding and activation";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR2";"SHC-mediated cascade:FGFR3";"FGFR3c ligand binding and activation";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR4";"Phospholipase C-mediated cascade, FGFR4";"Phospholipase C-mediated cascade, FGFR2";"FRS-mediated FGFR4 signaling";"SHC-mediated cascade:FGFR1";"SHC-mediated cascade:FGFR2";"FRS-mediated FGFR3 signaling";"PIP3 activates AKT signaling";"Signaling by FGFR1 in disease";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR4 signaling";"Signaling by activated point mutants of FGFR1";"Negative regulation of FGFR3 signaling";"FGFR3b ligand binding and activation";"FGFRL1 modulation of FGFR1 signaling";"FGFR4 ligand binding and activation";"PI-3K cascade:FGFR3";"Phospholipase C-mediated cascade: FGFR1" XP_015438972.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015434738.1 6 MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290 "Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_015430209.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_015433646.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-6804756 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Synthesis of PC";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation" XP_015430491.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_015434430.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_015432045.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015436426.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation" XP_015431447.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015436636.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015431408.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015434231.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015439722.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_015435986.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_015435149.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015437976.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_015429376.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015433514.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_015428562.1 57 Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974 "ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway" XP_015436558.1 6 MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species" XP_015434492.1 9 Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "tRNA modification in the nucleus and cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015432941.1 3 KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685 "Pyrimidine metabolism";"Purine metabolism";"Detoxification of Reactive Oxygen Species" XP_015428851.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015432222.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015433904.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015430259.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_015435578.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015433039.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015428952.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_015429588.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-8937144 "PPARA activates gene expression";"Endogenous sterols";"Xenobiotics";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling" XP_015431244.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015428779.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015435892.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" XP_015430445.1 5 Reactome: R-HSA-977347;KEGG: 00260+1.1.1.95;KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism" XP_015429127.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-73779 "HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_015430802.1 24 Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"MHC class II antigen presentation";"Recycling pathway of L1";"Mitotic Prometaphase";"Cilium Assembly";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" XP_015430205.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015437034.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015430763.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_015433850.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015429762.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015435000.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015432906.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_015432192.1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_015440519.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_015431484.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs" XP_015434247.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015438877.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_015429285.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015428806.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" XP_015430225.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015432286.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_015434861.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_015434477.1 6 Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin metabolism" XP_015437551.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015435395.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015432297.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015430361.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_015439890.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015436543.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_015438559.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_015430937.1 11 Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Ub-specific processing proteases";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_015433023.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015439827.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015434060.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_015429315.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_015431221.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015440365.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015436633.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015432636.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015436434.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_015429962.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015433708.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015428417.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015429995.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_015431318.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_015435105.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_015431122.1 8 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway" XP_015435361.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_015432271.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400 "VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer" XP_015440453.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015429064.1 3 Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_015429026.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015429371.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015438282.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_015429932.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377 "Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_015430337.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015438668.1 42 MetaCyc: PWY-7654;MetaCyc: PWY-6435;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-1361;MetaCyc: PWY-5177;MetaCyc: PWY-6944;KEGG: 00627+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-5109;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7216;MetaCyc: PWY-6945;MetaCyc: PWY-6863;MetaCyc: PWY-7656;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-5138;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7726;MetaCyc: PWY-7401;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35 "(8E,10E)-dodeca-8,10-dienol biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Lysine degradation";"alpha-Linolenic acid metabolism";"2-methylpropene degradation";"Benzoyl-coa degradation I (aerobic)";"Glutaryl-coa degradation";"Androstenedione degradation";"Aminobenzoate degradation";"Tryptophan metabolism";"Geraniol degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Toluene degradation";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"Methyl tert-butyl ether degradation";"Fermentation to 2-methylbutanoate";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Pyruvate fermentation to hexanol (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid elongation";"Methyl ketone biosynthesis (engineered)";"Butanoate metabolism";"Fatty acid salvage";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Benzoate degradation";"beta-Alanine metabolism";"Fatty acid degradation";"Phenylalanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Butanoate metabolism" XP_015430863.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015429599.1 6 Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-5685939 "Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)" XP_015432000.1 8 Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_015439500.1 15 Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938 "Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)" XP_015428399.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_015431403.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015430059.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_015435435.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015433032.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015434976.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis" XP_015439446.1 3 Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511 "Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination" XP_015430412.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_015439778.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015439629.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015432921.1 16 Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174178 "CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015431402.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_015437971.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_015434911.1 26 Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257 "Gap junction assembly";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Recycling pathway of L1";"Mitotic Prometaphase";"Cilium Assembly";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" XP_015435961.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015435119.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015439503.1 14 MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6999;Reactome: R-HSA-74259;MetaCyc: PWY-6596;MetaCyc: PWY-6607;MetaCyc: PWY-6538;KEGG: 00983+1.17.3.2;KEGG: 00230+1.17.1.4+1.17.3.2;Reactome: R-HSA-8851680;KEGG: 00232+1.17.3.2 "Guanosine nucleotides degradation III";"Purine metabolism";"Inosine 5'-phosphate degradation";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Theophylline degradation";"Purine catabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Drug metabolism - other enzymes";"Purine metabolism";"Butyrophilin (BTN) family interactions";"Caffeine metabolism" XP_015436609.1 6 KEGG: 00030+5.1.3.1;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Rubisco shunt" XP_015433698.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015432446.1 6 MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_015432659.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015430964.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015435179.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_015431886.1 3 MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_015438425.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015435692.1 7 KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25 "Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_015437142.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015432670.1 3 MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17 "Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism" XP_015438870.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015429024.1 4 MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_015438459.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015439254.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_015431553.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_015438241.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69017 "Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Neddylation";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6" XP_015434092.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_015428443.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015436716.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015433079.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_015432709.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_015437255.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_015432628.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015432182.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_015429154.1 4 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation elongation" XP_015433554.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015435056.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_015435691.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015438595.1 10 MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11 "1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway" XP_015434260.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015437942.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015433048.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015430011.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015432410.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_015434010.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015436022.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_015433510.1 7 Reactome: R-HSA-5689880;Reactome: R-HSA-171319;Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-5689603;Reactome: R-HSA-201722;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"UCH proteinases";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones" XP_015437040.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015436198.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_015438270.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_015436285.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015429874.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_015439809.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015433164.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608 "Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation" XP_015428817.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_015432538.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_015432699.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015433532.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_015439600.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015436014.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015434136.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015437414.1 5 Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69205 "CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription" XP_015430218.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015434257.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015431545.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_015430272.1 10 MetaCyc: PWY-6886;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00010+2.7.2.3 "1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_015436284.1 11 Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-450341;Reactome: R-HSA-2559582;Reactome: R-HSA-5687128;Reactome: R-HSA-2871796;Reactome: R-HSA-8862803;Reactome: R-HSA-8943724;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472 "Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Activation of the AP-1 family of transcription factors";"Senescence-Associated Secretory Phenotype (SASP)";"MAPK6/MAPK4 signaling";"FCERI mediated MAPK activation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Regulation of PTEN gene transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_015439736.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015434806.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015438952.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015431471.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_015435758.1 4 MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040 "Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis" XP_015432879.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015432916.1 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway" XP_015437822.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_015440382.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015428895.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015437274.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015433879.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015440388.1 7 MetaCyc: PWY-7039;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4 "Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PG";"Synthesis of PA";"Glycerophospholipid metabolism" XP_015437867.1 15 KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40 "Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Purine metabolism" XP_015432894.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015431480.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_015435682.1 6 Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6907 "Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)" XP_015438260.1 4 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255 "HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis" XP_015430944.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015432887.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_015438415.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015435748.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation" XP_015435882.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_015439403.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015435881.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome" XP_015429039.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015437396.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015433614.1 8 KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1 "Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine salvage";"Purine deoxyribonucleosides degradation II" XP_015436592.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015437162.1 13 Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-416993 "Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors" XP_015436729.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015439445.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015435204.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_015434702.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-881907;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events" XP_015434600.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_015430100.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_015436076.1 7 Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism" XP_015433813.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" XP_015436514.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015431217.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015434846.1 6 MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11 "Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_015436233.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_015436181.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015439171.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015436764.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015440352.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015433915.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_015439708.1 5 MetaCyc: PWY-5046;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4 "2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism" XP_015440132.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015439982.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" XP_015437616.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015428798.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015435547.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_015429300.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015432367.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-180534 "ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4" XP_015432386.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-167590 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation" XP_015439983.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015431172.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_015434427.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_015440460.1 30 Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-8941332;Reactome: R-HSA-69202;Reactome: R-HSA-198693;Reactome: R-HSA-389513;Reactome: R-HSA-198323;Reactome: R-HSA-392451;Reactome: R-HSA-69656;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-111447;Reactome: R-HSA-199418;Reactome: R-HSA-1358803;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-211163;Reactome: R-HSA-9614399;Reactome: R-HSA-8876198;Reactome: R-HSA-9634638;Reactome: R-HSA-6804758;KEGG: 04714+2.7.11.1 "CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"RUNX2 regulates genes involved in cell migration";"Cyclin E associated events during G1/S transition";"AKT phosphorylates targets in the nucleus";"CTLA4 inhibitory signaling";"AKT phosphorylates targets in the cytosol";"G beta:gamma signalling through PI3Kgamma";"Cyclin A:Cdk2-associated events at S phase entry";"Human cytomegalovirus infection";"Regulation of PTEN stability and activity";"Activation of BAD and translocation to mitochondria";"Negative regulation of the PI3K/AKT network";"Downregulation of ERBB2:ERBB3 signaling";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"AKT-mediated inactivation of FOXO1A";"Regulation of localization of FOXO transcription factors";"RAB GEFs exchange GTP for GDP on RABs";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of TP53 Activity through Acetylation";"Thermogenesis" XP_015436845.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015434417.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_015438608.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015440264.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_015433280.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_015440328.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015432186.1 17 Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2 "Carnitine metabolism";"3-hydroxypropanoate cycle";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes" XP_015435897.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7587 "CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)" XP_015434523.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_015438419.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_015430431.1 19 Reactome: R-HSA-3214858;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-8876725;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Protein methylation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015429548.1 18 Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200 "mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_015438788.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_015432198.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_015429242.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015440448.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_015435251.1 2 Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_015429805.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_015438789.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015438756.1 8 MetaCyc: PWY-1861;Reactome: R-HSA-6791055;Reactome: R-HSA-8950505;Reactome: R-HSA-163754;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;KEGG: 00030+2.2.1.2 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway" XP_015432021.1 16 Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-2559582 "Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)" XP_015433347.1 29 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-174437;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5656169;Reactome: R-HSA-3371511;Reactome: R-HSA-68962;Reactome: R-HSA-5693607 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Translesion synthesis by POLI";"Removal of the Flap Intermediate from the C-strand";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Termination of translesion DNA synthesis";"HSF1 activation";"Activation of the pre-replicative complex";"Processing of DNA double-strand break ends" XP_015440050.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015430932.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015429878.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015439149.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_015440343.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_015429030.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015440247.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_015439808.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015432755.1 23 Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-8964616;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-420092 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G beta:gamma signalling through CDC42";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"G alpha (z) signalling events";"G alpha (s) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors" XP_015436965.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015432135.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_015429140.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015436589.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_015432331.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes" XP_015437601.1 179 Reactome: R-HSA-209543;Reactome: R-HSA-1295596;Reactome: R-HSA-6804756;Reactome: R-HSA-2173795;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-917937;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-6791226;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-3785653;Reactome: R-HSA-5357956;Reactome: R-HSA-937041;Reactome: R-HSA-6804757;Reactome: R-HSA-975957;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-168928;Reactome: R-HSA-5610785;Reactome: R-HSA-5675221;Reactome: R-HSA-936964;Reactome: R-HSA-5655862;Reactome: R-HSA-192823;Reactome: R-HSA-3322077;Reactome: R-HSA-5610783;Reactome: R-HSA-2979096;Reactome: R-HSA-937042;Reactome: R-HSA-1253288;Reactome: R-HSA-1799339;Reactome: R-HSA-9613829;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-6782210;Reactome: R-HSA-4641263;Reactome: R-HSA-2565942;Reactome: R-HSA-168927;Reactome: R-HSA-9033241;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5689896;Reactome: R-HSA-9020702;Reactome: R-HSA-6781827;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-5656169;Reactome: R-HSA-917729;Reactome: R-HSA-1358803;Reactome: R-HSA-5357905;Reactome: R-HSA-2408557;Reactome: R-HSA-9014325;Reactome: R-HSA-211733;Reactome: R-HSA-912631;Reactome: R-HSA-5687128;Reactome: R-HSA-110320;Reactome: R-HSA-975956;Reactome: R-HSA-9013973;Reactome: R-HSA-2691232;Reactome: R-HSA-5654727;Reactome: R-HSA-9637628;Reactome: R-HSA-69231;Reactome: R-HSA-1236974;Reactome: R-HSA-5675482;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-349425;Reactome: R-HSA-5654726;Reactome: R-HSA-901032;Reactome: R-HSA-2173788;Reactome: R-HSA-8951664;Reactome: R-HSA-5696397;Reactome: R-HSA-936440;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-1169408;Reactome: R-HSA-4608870;Reactome: R-HSA-8876493;Reactome: R-HSA-9646399;Reactome: R-HSA-5656121;Reactome: R-HSA-5689901;Reactome: R-HSA-8866654;Reactome: R-HSA-209560;Reactome: R-HSA-174084;Reactome: R-HSA-205043;Reactome: R-HSA-6782135;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174490;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-975163;Reactome: R-HSA-5654733;Reactome: R-HSA-9615710;Reactome: R-HSA-5696400;Reactome: R-HSA-975110;Reactome: R-HSA-110314;Reactome: R-HSA-174048;Reactome: R-HSA-9645460;Reactome: R-HSA-156827;Reactome: R-HSA-174178;Reactome: R-HSA-156902;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-8863795;Reactome: R-HSA-1236382;Reactome: R-HSA-4641258;Reactome: R-HSA-2122948;Reactome: R-HSA-5684264;Reactome: R-HSA-180534;Reactome: R-HSA-5696394;Reactome: R-HSA-8875360;Reactome: R-HSA-2559580;Reactome: R-HSA-5685942;Reactome: R-HSA-162588;Reactome: R-HSA-6781823;Reactome: R-HSA-175474;Reactome: R-HSA-2894862;Reactome: R-HSA-5693565;Reactome: R-HSA-2122947;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-110312;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-3134975;Reactome: R-HSA-8849469;Reactome: R-HSA-72689;Reactome: R-HSA-2467813;Reactome: R-HSA-400253;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9636383;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-5654732;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-8866652;Reactome: R-HSA-3769402;Reactome: R-HSA-2173791;Reactome: R-HSA-5693607;Reactome: R-HSA-975144;Reactome: R-HSA-2644606;Reactome: R-HSA-937039;Reactome: R-HSA-72764;Reactome: R-HSA-195253;Reactome: R-HSA-5689877;Reactome: R-HSA-68827;Reactome: R-HSA-532668;Reactome: R-HSA-179409;Reactome: R-HSA-8948747;Reactome: R-HSA-68949;Reactome: R-HSA-445989;Reactome: R-HSA-8856828;Reactome: R-HSA-201681;Reactome: R-HSA-69601;Reactome: R-HSA-9013507;Reactome: R-HSA-450321;Reactome: R-HSA-9633012;Reactome: R-HSA-2672351;Reactome: R-HSA-69541;Reactome: R-HSA-8856825;Reactome: R-HSA-72706;Reactome: R-HSA-2559582;Reactome: R-HSA-6804760;Reactome: R-HSA-174113;Reactome: R-HSA-5610780 "p75NTR recruits signalling complexes";"Spry regulation of FGF signaling";"Regulation of TP53 Activity through Phosphorylation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Iron uptake and transport";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Myoclonic epilepsy of Lafora";"TNFR1-induced NFkappaB signaling pathway";"IKK complex recruitment mediated by RIP1";"Regulation of TP53 Degradation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of MAPK pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Translesion synthesis by POLK";"Viral mRNA Translation";"Glycogen synthesis";"Degradation of GLI2 by the proteasome";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"Downregulation of ERBB4 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Chaperone Mediated Autophagy";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of FZD by ubiquitination";"Regulation of PLK1 Activity at G2/M Transition";"TICAM1, RIP1-mediated IKK complex recruitment";"Peroxisomal protein import";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ovarian tumor domain proteases";"Interleukin-1 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"Termination of translesion DNA synthesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TNFR1 signaling";"Selenocysteine synthesis";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of signaling by CBL";"MAPK6/MAPK4 signaling";"Translesion Synthesis by POLH";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TICAM1-dependent activation of IRF3/IRF7";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Negative regulation of FGFR2 signaling";"Modulation by Mtb of host immune system";"Cyclin D associated events in G1";"ER-Phagosome pathway";"Regulation of necroptotic cell death";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of FGFR1 signaling";"ER Quality Control Compartment (ERQC)";"Downregulation of TGF-beta receptor signaling";"Neddylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Negative regulators of DDX58/IFIH1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"ISG15 antiviral mechanism";"Asymmetric localization of PCP proteins";"InlA-mediated entry of Listeria monocytogenes into host cells";"Aggrephagy";"Translesion synthesis by POLI";"Metalloprotease DUBs";"E3 ubiquitin ligases ubiquitinate target proteins";"NF-kB is activated and signals survival";"Autodegradation of Cdh1 by Cdh1:APC/C";"NRIF signals cell death from the nucleus";"Dual incision in TC-NER";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Membrane binding and targetting of GAG proteins";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Negative regulation of FGFR4 signaling";"Late endosomal microautophagy";"Dual Incision in GG-NER";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Alpha-protein kinase 1 signaling pathway";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Peptide chain elongation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Degradation of DVL";"Activated NOTCH1 Transmits Signal to the Nucleus";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Vpu mediated degradation of CD4";"DNA Damage Recognition in GG-NER";"InlB-mediated entry of Listeria monocytogenes into host cell";"Oxidative Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Budding and maturation of HIV virion";"Formation of TC-NER Pre-Incision Complex";"Assembly Of The HIV Virion";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"NOTCH1 Intracellular Domain Regulates Transcription";"EGFR downregulation";"Negative regulation of MET activity";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translesion synthesis by REV1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Regulation of innate immune responses to cytosolic DNA";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Formation of a pool of free 40S subunits";"Separation of Sister Chromatids";"Circadian Clock";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Prevention of phagosomal-lysosomal fusion";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Negative regulation of FGFR3 signaling";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Deactivation of the beta-catenin transactivating complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Processing of DNA double-strand break ends";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"IRAK1 recruits IKK complex";"Eukaryotic Translation Termination";"Degradation of beta-catenin by the destruction complex";"Josephin domain DUBs";"CDT1 association with the CDC6:ORC:origin complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of PTEN localization";"Orc1 removal from chromatin";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Clathrin-mediated endocytosis";"TCF dependent signaling in response to WNT";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Stimuli-sensing channels";"Stabilization of p53";"Cargo recognition for clathrin-mediated endocytosis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of TP53 Activity through Methylation";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome" XP_015438592.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015435270.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_015431021.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015429027.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015438254.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_015429223.1 17 MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage" XP_015429875.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015433387.1 12 Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-6796648 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes" XP_015438526.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_015440485.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854 "SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"HCMV Early Events";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly" XP_015432656.1 15 Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_015435679.1 32 Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-8851708 "Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Estrogen-dependent gene expression";"Signaling by FGFR2 IIIa TM" XP_015436769.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015429760.1 11 Reactome: R-HSA-8964539;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2 "Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism" XP_015432658.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015439523.1 9 MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043 "2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"PLC beta mediated events" XP_015438235.1 6 KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66 "Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_015433261.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015436171.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015430526.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176409 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins" XP_015431498.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_015439409.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_015437377.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane" XP_015429400.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015437310.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis" XP_015430044.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015430347.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_015428658.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015438648.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015438404.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_015430946.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015438326.1 6 Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788 "Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling" XP_015439092.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015437335.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015437263.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015432285.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_015436899.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA" XP_015437829.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_015437514.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015431550.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_015433957.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015435937.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_015433157.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015437769.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015431964.1 6 Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6798695;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135 "Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Neutrophil degranulation";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER" XP_015428830.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-8055 "Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis" XP_015440473.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_015429422.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_015432067.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015432187.1 17 Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_015433426.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_015431231.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015438126.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015429693.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015430713.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake" XP_015434987.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_015431481.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_015434731.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_015440103.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015430219.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_015436610.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-73779 "Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_015432119.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015439530.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015436313.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_015436183.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015439633.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_015431147.1 13 Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-416993 "Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors" XP_015429435.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_015436493.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015435366.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015436872.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015436250.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_015431257.1 4 MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism" XP_015431473.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015430680.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_015436537.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_015433598.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_015430678.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_015435165.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_015431406.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015437946.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_015440340.1 3 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes" XP_015439233.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015438889.1 12 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-72662 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S" XP_015440383.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015433396.1 52 Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-180585 "Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G" XP_015433349.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015440087.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_015438656.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015437935.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015431627.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" XP_015433094.1 7 KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-8964208 "Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylketonuria";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism" XP_015438860.1 4 Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I" XP_015440079.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015436499.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015428603.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015438962.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_015433409.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015429834.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168 "ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)" XP_015430150.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015431847.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_015440135.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015437380.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_015435315.1 9 Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202 "Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition" XP_015439590.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015429908.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015428906.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_015440420.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_015440245.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015430321.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015440030.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015433251.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015429058.1 11 KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection" XP_015430346.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_015433736.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015436770.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015434510.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015436157.1 9 Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_015433564.1 17 Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-8951664;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174178 "Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"Neddylation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015436870.1 10 Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_015429542.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_015438644.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_015436410.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_015430765.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015431158.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones" XP_015439156.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015435258.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_015436864.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_015431346.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015435324.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015428402.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_015439348.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_015428440.1 6 MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761 "Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_015434584.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015435054.1 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling" XP_015428807.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015432710.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_015433345.1 10 MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10 "Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Butanoate metabolism" XP_015438958.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_015435771.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_015436134.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_015428884.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015429768.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_015440285.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_015430664.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_015433968.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015429666.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_015428646.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_015430024.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_015432376.1 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_015436577.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015430893.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_015432470.1 17 Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-6796648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-75035;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-8953750;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Processing of DNA double-strand break ends";"Thermogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TP53 Regulates Transcription of DNA Repair Genes";"Human cytomegalovirus infection";"Signaling by SCF-KIT";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Transcriptional Regulation by E2F6";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_015438475.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_015438605.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015429573.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015430902.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015434025.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" XP_015432080.1 5 KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20 "One carbon pool by folate";"Folate transformations I";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes" XP_015432607.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015434485.1 3 Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_015428929.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_015430277.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_015430954.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_015431990.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015436399.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015432510.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_015433488.1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690 "SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events" XP_015437009.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015437821.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015434915.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_015432999.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_015435403.1 42 Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-3214858;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-5693565;Reactome: R-HSA-110329;Reactome: R-HSA-9609690;Reactome: R-HSA-2559582;Reactome: R-HSA-606279;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-2299718;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-3214815;Reactome: R-HSA-69473;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-73728;Reactome: R-HSA-212300;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-201722;Reactome: R-HSA-427359;Reactome: R-HSA-3214842;Reactome: R-HSA-427413;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-3214847;Reactome: R-HSA-73772 "HCMV Late Events";"SUMOylation of chromatin organization proteins";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RMTs methylate histone arginines";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"DNA methylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged pyrimidine";"HCMV Early Events";"Senescence-Associated Secretory Phenotype (SASP)";"Deposition of new CENPA-containing nucleosomes at the centromere";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"HDACs deacetylate histones";"G2/M DNA damage checkpoint";"Amyloid fiber formation";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Opening";"PRC2 methylates histones and DNA";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"Formation of the beta-catenin:TCF transactivating complex";"SIRT1 negatively regulates rRNA expression";"HDMs demethylate histones";"NoRC negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HATs acetylate histones";"RNA Polymerase I Promoter Escape" XP_015430375.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015432469.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015431279.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015438183.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015431510.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_015429944.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_015430993.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_015436511.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_015433673.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015428784.1 4 Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex" XP_015430911.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"Neutrophil degranulation" XP_015438406.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9022692 "Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity" XP_015432850.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015438016.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_015437082.1 4 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism" XP_015431892.1 7 KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism" XP_015438646.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_015430065.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_015433232.1 5 Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981 "Synthesis of PA";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III" XP_015438207.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015432014.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025 "WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_015433047.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015430318.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015437180.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015428847.1 6 Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693 "FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling" XP_015431526.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015433350.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015440080.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015439073.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_015429947.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_015434643.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015436189.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway" XP_015429596.1 57 Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258 "MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL" XP_015437239.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_015434105.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015437021.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_015430229.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015437190.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_015428980.1 6 MetaCyc: PWY-6608;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-6606;Reactome: R-HSA-74259 "Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine catabolism" XP_015432648.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015432923.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015429208.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_015432862.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_015429002.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_015430681.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP" XP_015439952.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_015431914.1 6 Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565 "ESR-mediated signaling";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015433883.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015434376.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_015434569.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015434358.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015435010.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015432375.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_015440106.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_015437519.1 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_015439826.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015436741.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015433395.1 52 Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-68827 "Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex" XP_015436900.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187 "Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress" XP_015431125.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015439406.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015435950.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_015433633.1 3 Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_015433670.1 56 Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236 "Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_015432411.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_015436212.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015429641.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015439876.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_015440360.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_015431551.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015439946.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015437316.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_015439878.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015436320.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_015429185.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_015439416.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" XP_015435664.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015439257.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_015432907.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_015440432.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015433451.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015438937.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_015430025.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_015439576.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_015438929.1 3 Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331 "Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine" XP_015432930.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_015433863.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015439662.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_015434400.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015438719.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015438087.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015435040.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015438524.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015430088.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_015429117.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015438011.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015433282.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015434663.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_015433006.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015434858.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015429903.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015429716.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_015440255.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_015439899.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_015429463.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_015433779.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_015438463.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015436941.1 10 Reactome: R-HSA-4719360;MetaCyc: PWY-7979;MetaCyc: PWY-7661;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;MetaCyc: PWY-7922;Reactome: R-HSA-162699 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation III (mammals, core M3)";"Protein N-glycosylation (Haloferax volcanii)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose" XP_015440516.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015439372.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation" XP_015433460.1 4 Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-8939211 "Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"ESR-mediated signaling" XP_015431017.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015428759.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-182971 "Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"EGFR downregulation" XP_015433890.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015433432.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015431608.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015430865.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015438488.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015432243.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015439961.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015431873.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015437852.1 10 Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-975634;Reactome: R-HSA-3000171;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864;MetaCyc: PWY-5691;MetaCyc: PWY-7394 "The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Amyloid fiber formation";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin III";"Purine metabolism";"Retinoid cycle disease events";"Urate conversion to allantoin I";"Urate conversion to allantoin II" XP_015439241.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_015431995.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015436109.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_015440221.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015436964.1 8 KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171 "Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis" XP_015436170.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015429723.1 24 Reactome: R-HSA-180024;Reactome: R-HSA-4420097;Reactome: R-HSA-8853659;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-111931;Reactome: R-HSA-9010642;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5621575;Reactome: R-HSA-9634600;Reactome: R-HSA-8963896;Reactome: R-HSA-983231;Reactome: R-HSA-163560;Reactome: R-HSA-5610780;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-5687128;Reactome: R-HSA-442720;Reactome: R-HSA-392517;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610783;Reactome: R-HSA-163358;Reactome: R-HSA-164378 "DARPP-32 events";"VEGFA-VEGFR2 Pathway";"RET signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"PKA-mediated phosphorylation of CREB";"ROBO receptors bind AKAP5";"mTOR signaling pathway";"CD209 (DC-SIGN) signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"HDL assembly";"Factors involved in megakaryocyte development and platelet production";"Triglyceride catabolism";"Degradation of GLI1 by the proteasome";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"MAPK6/MAPK4 signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Rap1 signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Degradation of GLI2 by the proteasome";"PKA-mediated phosphorylation of key metabolic factors";"PKA activation in glucagon signalling" XP_015437559.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015433817.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_015437047.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_015439027.1 17 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015432027.1 11 Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;Reactome: R-HSA-1660517;KEGG: 00562+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-168138 "Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Toll Like Receptor 9 (TLR9) Cascade" XP_015439151.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_015435064.1 33 Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-159227 "tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA" XP_015430226.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015434713.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015429926.1 5 KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Formation of apoptosome" XP_015437048.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_015436692.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015434162.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015434034.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_015431521.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015440355.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_015432701.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015432724.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015440110.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_015432451.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015428825.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015438589.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_015432972.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015435793.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015431356.1 11 Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-111457;Reactome: R-HSA-111464 "Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Respiratory electron transport";"Mitochondrial protein import";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_015432039.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015436856.1 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_015430884.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_015439091.1 13 MetaCyc: PWY-6367;Reactome: R-HSA-2029485;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;MetaCyc: PWY-6351;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-202433 "D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Generation of second messenger molecules" XP_015437322.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_015431405.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015435281.1 8 MetaCyc: PWY-7391;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-6174 "Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)" XP_015439328.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_015439624.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015439028.1 17 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_015430759.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015429297.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_015435074.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_015437008.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015432450.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015437436.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_015435407.1 10 KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922 "Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_015439187.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015437088.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015431422.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015434884.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_015434874.1 5 MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_015436837.1 7 KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_015439118.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_015430414.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_015439267.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_015434918.1 8 KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1 "Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis" XP_015435161.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_015431982.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015428750.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015429585.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015431845.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_015428916.1 5 Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation" XP_015432780.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7725 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_015430309.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_015438262.1 4 Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255 "HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis" XP_015433788.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_015431985.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015432619.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015437888.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015439462.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015432566.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015434008.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015432889.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015428791.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_015435749.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_015438802.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015431495.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015432969.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015432513.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015438700.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015437204.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_015435181.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015434942.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015431616.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015434141.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_015435957.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015429879.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015437146.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_015432608.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015428727.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015431351.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis" XP_015433995.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015428389.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015439035.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015439990.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015431470.1 5 Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32 "Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_015436234.1 9 Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-975634 "HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Retinoid metabolism and transport" XP_015435433.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_015433545.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015430962.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_015434588.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_015440543.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_015434148.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_015436588.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_015428891.1 7 Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" XP_015431729.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015436580.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015440439.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015430270.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015437704.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_015438329.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_015434142.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015436325.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_015438089.1 16 Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-180585 "TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G" XP_015430352.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015431506.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_015433421.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015434249.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015436598.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015438922.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_015439077.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015437768.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_015435173.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Cristae formation" XP_015439281.1 6 KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_015428524.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_015434649.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015428681.1 5 Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975 "STAT6-mediated induction of chemokines";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA" XP_015439102.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_015438852.1 7 MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-7839;MetaCyc: PWY-7836;MetaCyc: PWY-7838 "Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis" XP_015434458.1 13 MetaCyc: PWY-5132;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1 "Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Ethanol oxidation";"Chitin degradation to ethanol";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_015437538.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015433784.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015439172.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015431971.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_015429145.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_015436263.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_015430365.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015434484.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015432262.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015432968.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015431026.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_015431165.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015428983.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_015429867.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466 "Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis" XP_015432365.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015429603.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015432347.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015432617.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015429644.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015433710.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015429647.1 4 Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_015436201.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_015437320.1 33 Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015428859.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_015434805.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015439099.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_015439718.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411 "Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"DNA replication initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere" XP_015431362.1 4 KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50 "Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III";"Arginine and proline metabolism" XP_015439448.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015433972.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_015439839.1 13 Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_015432013.1 8 Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-432720 "Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis" XP_015429099.1 5 Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209560;Reactome: R-HSA-209543 "NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes" XP_015430686.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015432953.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_015436096.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_015433944.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015435155.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015430017.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015435962.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015440152.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015438445.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015439336.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_015439768.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_015436829.1 6 Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446 "Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination" XP_015436673.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015431223.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015437706.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_015433925.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015432754.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015436861.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598 "RHO GTPases Activate Formins";"Degradation of DVL";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins" XP_015433509.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015437967.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015433974.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_015434014.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015436267.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015433153.1 1 Reactome: R-HSA-419771 "Opsins" XP_015438511.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015432461.1 13 MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6969 "Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_015430880.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015435662.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015434609.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_015435960.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015436901.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015430933.1 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation" XP_015434192.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_015428430.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015433742.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_015433741.1 17 Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606 "Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_015438797.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_015433956.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015437740.1 11 Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-2426168;Reactome: R-HSA-9018519 "Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression" XP_015438579.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-174184 "Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_015434886.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015429521.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015433080.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_015440482.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015434015.1 26 Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907 "FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_015439085.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015436886.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015433707.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015429054.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015430003.1 8 Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083629 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_015435557.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015436800.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015432307.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015437638.1 5 Reactome: R-HSA-71336;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;MetaCyc: PWY-7180 "Pentose phosphate pathway";"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation" XP_015435032.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_015436776.1 7 MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-6471;KEGG: 00510+2.7.8.15;KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;Reactome: R-HSA-4549356 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2" XP_015433562.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015436204.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015432820.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015431254.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015431055.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_015434581.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015438075.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015435661.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015434286.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015435481.1 10 MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9 "Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes" XP_015430837.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015436875.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015430242.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-4381 "3-hydroxypropanoate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_015434369.1 3 Reactome: R-HSA-380994;Reactome: R-HSA-429947;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_015429839.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015440417.1 1 Reactome: R-HSA-8963901 "Chylomicron remodeling" XP_015431609.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015439620.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-2151201;Reactome: R-HSA-5689603 "HATs acetylate histones";"Transcriptional activation of mitochondrial biogenesis";"UCH proteinases" XP_015437440.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015433557.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168271 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus" XP_015439367.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_015428844.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015440487.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_015433346.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015432733.1 4 Reactome: R-HSA-4755609;Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis" XP_015433815.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_015430882.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015435544.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015436903.1 5 MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_015436865.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_015438639.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_015431310.1 12 KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00450+2.7.7.4 "Purine metabolism";"Sulfur metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Selenate reduction";"Sulfate activation for sulfonation";"Selenocompound metabolism" XP_015437923.1 26 Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148 "Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015432706.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-69231;Reactome: R-HSA-6804114 "G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest" XP_015429303.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_015433765.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592 "Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1" XP_015433989.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5218921 "Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Downstream signal transduction";"VEGFR2 mediated cell proliferation" XP_015438229.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Rho GTPase cycle";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"Human papillomavirus infection" XP_015429724.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015431952.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015431670.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015439649.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_015429370.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015428824.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015430276.1 12 Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847;Reactome: R-HSA-73762 "NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones";"RNA Polymerase I Transcription Initiation" XP_015430164.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015429348.1 15 Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174154 "Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin" XP_015433764.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)" XP_015434179.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015438280.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015437402.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015438466.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015435326.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015440251.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_015435330.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_015432425.1 13 KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690 "Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)" XP_015439675.1 12 KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783 "Arachidonic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen degradation" XP_015437949.1 3 KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" XP_015430936.1 11 Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Ub-specific processing proteases";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_015432609.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015429339.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015429567.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_015436757.1 12 MetaCyc: PWY-7385;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis" XP_015438212.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_015430729.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_015428956.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-168333 "SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_015432508.1 20 Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-735 "Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis" XP_015437750.1 27 Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-77588;Reactome: R-HSA-167152;Reactome: R-HSA-159236;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-72203;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-73856;Reactome: R-HSA-975956;Reactome: R-HSA-159227;Reactome: R-HSA-77595 "FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of the SLBP independent Mature mRNA";"Processing of Intronless Pre-mRNAs" XP_015430898.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_015430861.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015433998.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015431499.1 18 KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6642;MetaCyc: PWY-7117;MetaCyc: PWY-7383;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115 "Arginine biosynthesis";"Tyrosine metabolism";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Sulfolactate degradation III";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_015440490.1 57 Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050 "Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_015431154.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism" XP_015435975.1 18 MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053 "Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II" XP_015428569.1 4 Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331 "Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Taurine biosynthesis I" XP_015439852.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015432675.1 5 MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism" XP_015432443.1 6 Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression" XP_015434897.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015431571.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015430803.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736 "Recycling pathway of L1";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors" XP_015439067.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_015438917.1 15 Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548 "DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks" XP_015438027.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids" XP_015435438.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015429837.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" XP_015431208.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015435678.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015438277.1 24 Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218920;Reactome: R-HSA-5218921;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-392451;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;Reactome: R-HSA-114604;Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-202424;Reactome: R-HSA-389357;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"RSK activation";"VEGFR2 mediated vascular permeability";"VEGFR2 mediated cell proliferation";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"GPVI-mediated activation cascade";"Activation of AKT2";"Human immunodeficiency virus 1 infection";"FCERI mediated NF-kB activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"mTOR signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Downstream TCR signaling";"CD28 dependent PI3K/Akt signaling";"Integrin signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015430612.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_015429503.1 4 Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance" XP_015430485.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015435101.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337 "Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding" XP_015438424.1 5 MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system" XP_015431387.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015436051.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_015428782.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_015435564.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015428400.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_015431651.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_015434447.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015428947.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015432956.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015428736.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015428618.1 5 Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122 "Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015435594.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015436366.1 6 MetaCyc: PWY-6731;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-7238 "Starch degradation III";"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Sucrose biosynthesis II" XP_015440215.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015432266.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_015429479.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015439758.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation" XP_015435538.1 4 MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285 "Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis" XP_015432237.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015439933.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015432500.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_015435164.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_015430551.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_015438082.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015433412.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015430652.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015433461.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_015433405.1 14 MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-4302;MetaCyc: PWY-7279;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105 "Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Respiratory electron transport" XP_015432207.1 13 KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902 "Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)" XP_015437531.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_015429304.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_015437761.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015435144.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria" XP_015436482.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_015434455.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_015429898.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" XP_015437228.1 7 MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14 "UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Drug metabolism - other enzymes" XP_015437875.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015435486.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015437412.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_015435702.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702 "Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I" XP_015436638.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015429369.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015430391.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_015436255.1 5 Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-162710 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_015440084.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_015434478.1 7 KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis" XP_015438426.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_015433543.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015440154.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015437497.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015439626.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_015440145.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_015436150.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015435633.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015429706.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015432877.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015430085.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015436594.1 3 MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_015429098.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015430343.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_015439793.1 3 Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13 "G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_015440015.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_015438602.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015430387.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_015438074.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015433020.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015431821.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_015434864.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015433052.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_015434073.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_015439868.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_015433294.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex" XP_015430903.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015434677.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015436807.1 4 KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895 "Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism" XP_015435803.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_015437883.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015439836.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans" XP_015430289.1 14 MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036 "Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_015430123.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_015430327.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_015440295.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_015435115.1 4 Reactome: R-HSA-917937;Reactome: R-HSA-189483;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874 "Iron uptake and transport";"Heme degradation";"Porphyrin and chlorophyll metabolism";"Heme degradation I" XP_015439066.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_015432111.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015430842.1 16 Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167200 "Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_015434849.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015432932.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_015430735.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_015435554.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015429910.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015440099.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_015429986.1 14 Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-75955 "Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation" XP_015438165.1 17 Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-69166 "Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate" XP_015437272.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015431219.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_015438703.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_015432361.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_015433040.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015440462.1 30 KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804759;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-6804757;Reactome: R-HSA-69202;Reactome: R-HSA-198323;Reactome: R-HSA-392451;Reactome: R-HSA-389513;Reactome: R-HSA-198693;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-111447;Reactome: R-HSA-69656;Reactome: R-HSA-5218920;Reactome: R-HSA-199418;Reactome: R-HSA-1358803;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-9634638;Reactome: R-HSA-211163;Reactome: R-HSA-9614399;Reactome: R-HSA-8876198;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804758 "mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"RUNX2 regulates genes involved in cell migration";"Regulation of TP53 Degradation";"Cyclin E associated events during G1/S transition";"AKT phosphorylates targets in the cytosol";"G beta:gamma signalling through PI3Kgamma";"CTLA4 inhibitory signaling";"AKT phosphorylates targets in the nucleus";"Human cytomegalovirus infection";"Regulation of PTEN stability and activity";"Activation of BAD and translocation to mitochondria";"Cyclin A:Cdk2-associated events at S phase entry";"VEGFR2 mediated vascular permeability";"Negative regulation of the PI3K/AKT network";"Downregulation of ERBB2:ERBB3 signaling";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"AKT-mediated inactivation of FOXO1A";"Regulation of localization of FOXO transcription factors";"RAB GEFs exchange GTP for GDP on RABs";"Thermogenesis";"Regulation of TP53 Activity through Acetylation" XP_015430463.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015436804.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015436467.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015428921.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_015433286.1 12 Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.25;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-8853383;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916 "MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Lysosomal oligosaccharide catabolism";"HS-GAG degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Hyaluronan uptake and degradation" XP_015435042.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015430966.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015429831.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015434919.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015429579.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_015431367.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015439762.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015437093.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_015434311.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;MetaCyc: PWY-7511 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Protein ubiquitination" XP_015434904.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015436733.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015429690.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_015435063.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_015439595.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015434520.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_015432869.1 14 Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788 "Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling" XP_015428541.1 5 KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism" XP_015435319.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_015437275.1 5 Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_015432741.1 10 MetaCyc: PWY-6453;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7411 "Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)" XP_015433359.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015434794.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015438432.1 13 KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392 "Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II" XP_015431462.1 3 MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_015434710.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_015434992.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015437099.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015432750.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_015431385.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015439134.1 17 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-6783310;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway" XP_015434184.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-912631 "Downstream signal transduction";"MET activates RAP1 and RAC1";"MET receptor recycling";"Regulation of signaling by CBL" XP_015429326.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616 "Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication" XP_015429721.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015439499.1 3 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation" XP_015428550.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015434319.1 5 Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_015434375.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_015429195.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015438566.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015436195.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_015430809.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-9620244 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation";"Regulation of MECP2 expression and activity";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation" XP_015435275.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015429528.1 3 Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096 "MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation" XP_015431861.1 29 Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827 "Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_015431843.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015429224.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097 "mTOR signaling pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway" XP_015430640.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_015435383.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015434650.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_015438588.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015436312.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_015439843.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015439331.1 8 KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_015439794.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_015440452.1 3 Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3 "Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism" XP_015439232.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015434659.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015433886.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015431705.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_015432356.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015432117.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015431732.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_015436239.1 4 KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132 "N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_015438750.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_015433790.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015430191.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015436256.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015438231.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015433877.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015436578.1 14 Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-181;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1 "Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Folate transformations I";"Cyanoamino acid metabolism";"Glycine betaine degradation I";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)" XP_015438623.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015430345.1 10 KEGG: 00562+5.3.1.1;KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00051+5.3.1.1 "Inositol phosphate metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism" XP_015440155.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015431832.1 6 MetaCyc: PWY-5067;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3322077;MetaCyc: PWY-622 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen synthesis";"Starch biosynthesis" XP_015430476.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_015438717.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_015439498.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015439346.1 4 Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism" XP_015439883.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015439016.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015432729.1 5 Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2 "Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_015431036.1 3 Reactome: R-HSA-1296072;Reactome: R-HSA-5576893;Reactome: R-HSA-5576890 "Voltage gated Potassium channels";"Phase 2 - plateau phase";"Phase 3 - rapid repolarisation" XP_015432957.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015436641.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015430666.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_015438020.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015440017.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015432179.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_015436846.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_015430623.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_015434113.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015433797.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015429648.1 13 KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662 "Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling" XP_015437466.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_015430712.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_015432762.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7601 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_015437719.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_015431144.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_015440165.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015428871.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015436116.1 13 MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822 "Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_015436396.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_015436182.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015440454.1 25 Reactome: R-HSA-8939256;Reactome: R-HSA-8931987;Reactome: R-HSA-8934593;Reactome: R-HSA-8940973;Reactome: R-HSA-8936459;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-8941326;Reactome: R-HSA-8941332;Reactome: R-HSA-8951911;Reactome: R-HSA-8935964;Reactome: R-HSA-8949275;Reactome: R-HSA-8939236;Reactome: R-HSA-8939243;Reactome: R-HSA-8939245;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8941333;Reactome: R-HSA-8941284;Reactome: R-HSA-8939242;Reactome: R-HSA-8939247;Reactome: R-HSA-8939246;Reactome: R-HSA-8951936;Reactome: R-HSA-9616222;Reactome: R-HSA-8878166 "RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"RUNX2 regulates bone development";"RUNX2 regulates genes involved in cell migration";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates expression of components of tight junctions";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in BCR signaling";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF";"Transcriptional regulation of granulopoiesis";"Transcriptional regulation by RUNX2" XP_015429360.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015430160.1 22 MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7602;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-7724;MetaCyc: PWY-7726;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;Reactome: R-HSA-75876 "(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs" XP_015436289.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events" XP_015433146.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015435328.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015429554.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_015434658.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015439255.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_015430300.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015432929.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_015435863.1 9 Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_015430031.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015436324.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015437629.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_015437784.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015430810.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946 "Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"RAF activation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants" XP_015440494.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_015428539.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_015429881.1 6 KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980 "Photosynthesis";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Cristae formation";"ATP biosynthesis" XP_015437027.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_015432550.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015434074.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015434494.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015428715.1 13 MetaCyc: PWY-6383;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7141 "Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis" XP_015431479.1 11 Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167243 "Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery" XP_015433827.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015436382.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015440497.1 9 Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-69017 "Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6" XP_015440474.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-6784531 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus" XP_015439800.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015437229.1 7 KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176 "Drug metabolism - other enzymes";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis" XP_015429870.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015429134.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168 "ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)" XP_015429133.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_015432776.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_015431082.1 13 KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7198;Reactome: R-HSA-499943 "Glutathione metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates" XP_015435878.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015433051.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_015430665.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015438880.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015436889.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015428552.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_015438021.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015430460.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015433542.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015438414.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378 "Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling" XP_015440377.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015430389.1 7 MetaCyc: PWY-3385;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7818;MetaCyc: PWY-7782;MetaCyc: PWY-7886 "Choline biosynthesis I";"Synthesis of PC";"Glycerophospholipid metabolism";"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" XP_015436890.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015440085.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_015438874.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015434568.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015430282.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_015433341.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813 "CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids" XP_015436200.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015437411.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_015436806.1 3 Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691 "Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway";"Interleukin-20 family signaling" XP_015440114.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015429517.1 7 Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_015440275.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_015436392.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_015435282.1 8 MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-7391 "Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)" XP_015430471.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_015437314.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015435632.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015434442.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_015433158.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015440173.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015438284.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_015430429.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_015436144.1 6 Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015437520.1 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_015433701.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015431181.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015430380.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015430140.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015431723.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_015431328.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015430514.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015431816.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_015437286.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015435043.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_015431877.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_015434256.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_015432128.1 11 Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-909733;Reactome: R-HSA-432142;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-9008059;Reactome: R-HSA-210990 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"PD-1 signaling";"Interferon alpha/beta signaling";"Platelet sensitization by LDL";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"Interleukin-37 signaling";"PECAM1 interactions" XP_015438079.1 12 Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-75893;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-193692;Reactome: R-HSA-982772;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"TNF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Regulated proteolysis of p75NTR";"Growth hormone receptor signaling";"Signaling by EGFR" XP_015436510.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_015429765.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_015431574.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_015439784.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015435044.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_015430367.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015436629.1 5 MetaCyc: PWY-6853;Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88 "Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism" XP_015435288.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_015437471.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3 "Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism" XP_015438286.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815 "Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones" XP_015431926.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015430351.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis" XP_015435236.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015437953.1 10 Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells" XP_015432665.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015430571.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_015432054.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015434245.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015434671.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_015432540.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_015438948.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_015436006.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_015430772.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015430105.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;MetaCyc: PWY-7511 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Protein ubiquitination" XP_015430127.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015439443.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015432938.1 6 Reactome: R-HSA-5609978;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-70370 "Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose catabolism" XP_015428840.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_015434280.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_015438487.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_015438083.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_015432764.1 40 Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-8851708 "HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM" XP_015433613.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015437176.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_015431171.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_015437288.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015439260.1 15 Reactome: R-HSA-9020702;MetaCyc: PWY-6163;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-450321;KEGG: 00400+2.5.1.19;Reactome: R-HSA-937042;Reactome: R-HSA-9014325 "Interleukin-1 signaling";"Chorismate biosynthesis from 3-dehydroquinate";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Phenylalanine, tyrosine and tryptophan biosynthesis";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex" XP_015436542.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015437637.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_015432605.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015439355.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667 "Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I" XP_015433209.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_015429900.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015433693.1 3 Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17 "Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis" XP_015439358.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015432700.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis" XP_015433031.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015439581.1 17 MetaCyc: PWY-6608;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-6620;MetaCyc: PWY-6611;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627 "Guanosine nucleotides degradation III";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Adenine and adenosine salvage V";"Purine catabolism";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine metabolism";"Salinosporamide A biosynthesis" XP_015429934.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015438072.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015433301.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015429549.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015435138.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841 "Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines" XP_015437318.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015430682.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015437133.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015432368.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783 "FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome" XP_015431489.1 14 MetaCyc: PWY-4302;MetaCyc: PWY-7279;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1 "Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Butanoate metabolism" XP_015430158.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015438931.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015438854.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_015436115.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_015429649.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015438467.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_015430611.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_015430797.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_015428441.1 6 Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_015432621.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015431488.1 44 Reactome: R-HSA-3371453;Reactome: R-HSA-982772;Reactome: R-HSA-198753;Reactome: R-HSA-879415;Reactome: R-HSA-5673001;Reactome: R-HSA-2559582;Reactome: R-HSA-5654726;Reactome: R-HSA-8943724;Reactome: R-HSA-5663213;Reactome: R-HSA-9627069;Reactome: R-HSA-5668599;Reactome: R-HSA-6811558;Reactome: R-HSA-8939211;Reactome: R-HSA-6802948;Reactome: R-HSA-5675221;Reactome: R-HSA-5674499;Reactome: R-HSA-112409;Reactome: R-HSA-2559580;Reactome: R-HSA-5674135;Reactome: R-HSA-162658;Reactome: R-HSA-456926;Reactome: R-HSA-5654727;Reactome: R-HSA-2871796;Reactome: R-HSA-9649948;KEGG: 04150+2.7.11.24;Reactome: R-HSA-6802946;Reactome: R-HSA-450341;Reactome: R-HSA-74749;Reactome: R-HSA-375165;Reactome: R-HSA-444257;Reactome: R-HSA-170968;Reactome: R-HSA-9635465;Reactome: R-HSA-881907;Reactome: R-HSA-9634638;Reactome: R-HSA-202670;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-8940973;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-6802952;Reactome: R-HSA-445144;Reactome: R-HSA-2029482;Reactome: R-HSA-6802955 "Regulation of HSF1-mediated heat shock response";"Growth hormone receptor signaling";"ERK/MAPK targets";"Advanced glycosylation endproduct receptor signaling";"RAF/MAP kinase cascade";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR1 signaling";"Regulation of PTEN gene transcription";"RHO GTPases Activate WASPs and WAVEs";"Regulation of the apoptosome activity";"RHO GTPases Activate NADPH Oxidases";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ESR-mediated signaling";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Negative feedback regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"Oxidative Stress Induced Senescence";"MAP2K and MAPK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR2 signaling";"FCERI mediated MAPK activation";"Signaling downstream of RAS mutants";"mTOR signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Activation of the AP-1 family of transcription factors";"Signal attenuation";"NCAM signaling for neurite out-growth";"RSK activation";"Frs2-mediated activation";"Suppression of apoptosis";"Gastrin-CREB signalling pathway via PKC and MAPK";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"ERKs are inactivated";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"RUNX2 regulates osteoblast differentiation";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"Signaling by BRAF and RAF fusions";"Signal transduction by L1";"Regulation of actin dynamics for phagocytic cup formation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_015435277.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_015437698.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_015430738.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015431455.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_015429107.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015438057.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015428716.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015430452.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015430728.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_015430385.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_015432655.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440 "Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network" XP_015429667.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015435263.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" XP_015436649.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880 "Regulation of TP53 Degradation";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases" XP_015430268.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_015436839.1 11 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-69231 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1" XP_015433500.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015434793.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_015437164.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_015430026.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_015432056.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015431083.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_015430348.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_015428538.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_015431075.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_015436989.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015439424.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015436747.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_015431573.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_015429231.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" XP_015432552.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_015435450.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015431792.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_015438813.1 4 Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane" XP_015428737.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015432949.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_015432070.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_015433181.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_015435784.1 8 MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7197 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation" XP_015430808.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-442982 "HSF1-dependent transactivation";"RAF activation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Long-term potentiation";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor" XP_015436295.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015429646.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_015432723.1 11 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Human cytomegalovirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_015429119.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168325 "Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis" XP_015438509.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015438044.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_015430889.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015437546.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015433770.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779 "Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_015431049.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_015432114.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_015438059.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6807505 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes" XP_015430801.1 26 Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-389977 "Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"Cilium Assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway" XP_015429800.1 6 Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;MetaCyc: PWY-7391 "Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)" XP_015438654.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_015434629.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_015433155.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_015436291.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_015431562.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_015440138.1 2 Reactome: R-HSA-389957;Reactome: R-HSA-8953750 "Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6" XP_015430934.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_015435454.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015438422.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015434585.1 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_015431354.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015435257.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015436714.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_015430013.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_015436364.1 6 MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6731 "Starch degradation V";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation III" XP_015435356.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_015435667.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_015432596.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015428783.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015437722.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_015434203.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_015435367.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_015437880.1 10 KEGG: 00650+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;KEGG: 00640+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-5022;MetaCyc: PWY-4321;Reactome: R-HSA-916853 "Butanoate metabolism";"4-aminobutanoate degradation III";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"Propanoate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation I";"4-aminobutanoate degradation V";"L-glutamate degradation IV";"Degradation of GABA" XP_015432336.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_015431000.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015437614.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015438473.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015429106.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015438285.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_015433336.1 5 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-983231 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production" XP_015436963.1 8 KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171 "Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis" XP_015429431.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_015434161.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_015437445.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015436940.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015429234.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_015431614.1 4 Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_015434163.1 19 Reactome: R-HSA-6798695;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-6969;KEGG: 00720+2.3.3.8 "Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes" XP_015435421.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015432554.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015428604.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_015429988.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_015434194.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015432015.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-196025 "WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions" XP_015439775.1 10 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257 "Human papillomavirus infection";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Thermogenesis";"Human immunodeficiency virus 1 infection";"RSK activation" XP_015429350.1 7 MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I" XP_015438553.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_015438709.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_015437839.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_015431251.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_015435423.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015437130.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015439583.1 17 MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-6611;MetaCyc: PWY-6620;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1 "Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine catabolism";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Purine salvage";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II" XP_015436019.1 4 MetaCyc: PWY-7805;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III" XP_015430377.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015438173.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015435509.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis" XP_015440149.1 13 KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-7909;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-6613;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-3841;MetaCyc: PWY-5030 "Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"L-histidine degradation III" XP_015436611.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015433343.1 14 MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7589 "Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)" XP_015430444.1 5 KEGG: 00260+1.1.1.95;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95;KEGG: 00680+1.1.1.95 "Glycine, serine and threonine metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Methane metabolism" XP_015432908.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_015435285.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_015430064.1 14 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-68877 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Mitotic Prometaphase" XP_015436793.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_015428473.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015435491.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_015439213.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015433636.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_015440199.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015438291.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_015432970.1 9 KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902 "Other glycan degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)" XP_015434037.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015440109.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_015435143.1 31 MetaCyc: PWY-5973;MetaCyc: PWY-7388;MetaCyc: PWY-7664;MetaCyc: PWY-7858;MetaCyc: PWY-5994;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-8047;Reactome: R-HSA-75105;MetaCyc: PWY-5971;MetaCyc: PWY-5989;MetaCyc: PWY-4381;MetaCyc: PWYG-321;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-5366;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-8049 "Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Biotin metabolism";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitoleate biosynthesis II (plants and bacteria)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Pederin biosynthesis" XP_015432366.1 16 Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-164939 "Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"LDL clearance";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Nef mediated downregulation of CD28 cell surface expression" XP_015432050.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015431430.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_015436948.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_015431699.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015439015.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015434457.1 14 MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1622;MetaCyc: PWY-1042;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-8004 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I" XP_015436442.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015430720.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs" XP_015440241.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015436746.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_015430030.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015431577.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015435385.1 6 MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12 "Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis" XP_015436202.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-381676 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_015435700.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736 "Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors" XP_015438839.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015432671.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_015430398.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015429132.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_015438433.1 13 KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392 "Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II" XP_015434501.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015432449.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015437669.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015436319.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015431045.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015439851.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240 "Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism" XP_015436461.1 8 MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27 "Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Propanoate metabolism" XP_015439880.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015432488.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_015430290.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" XP_015434486.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_015429694.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015436942.1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" XP_015439074.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis" XP_015434118.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_015431304.1 29 Reactome: R-HSA-6804756;Reactome: R-HSA-912446;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-69541;Reactome: R-HSA-6796648;Reactome: R-HSA-5693548;Reactome: R-HSA-349425;Reactome: R-HSA-6803207;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-2559586;Reactome: R-HSA-6804760;KEGG: 05163+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"mTOR signaling pathway";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"Homologous DNA Pairing and Strand Exchange";"Stabilization of p53";"TP53 Regulates Transcription of DNA Repair Genes";"Sensing of DNA Double Strand Breaks";"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Thermogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Methylation";"Human cytomegalovirus infection" XP_015436529.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_015438278.1 24 Reactome: R-HSA-165158;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-354192;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-1257604;Reactome: R-HSA-444257;Reactome: R-HSA-5218920;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5607764;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1 "Activation of AKT2";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Integrin signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"VEGFR2 mediated cell proliferation";"PIP3 activates AKT signaling";"RSK activation";"VEGFR2 mediated vascular permeability";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"CLEC7A (Dectin-1) signaling";"RHO GTPases activate PKNs";"Human cytomegalovirus infection" XP_015436191.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_015431320.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_015434144.1 5 KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;Reactome: R-HSA-174403 "Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling" XP_015436823.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_015433054.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis" XP_015438777.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015438561.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_015437332.1 18 KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4 "alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Synthesis of PA";"Linoleic acid metabolism" XP_015439780.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015434473.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015436934.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_015435926.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_015438440.1 4 KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism" XP_015431407.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_015431030.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015430302.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015432035.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_015429189.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_015432252.1 9 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208 "TP53 Regulates Metabolic Genes";"Macroautophagy";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling" XP_015440037.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_015428445.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_015431020.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015436957.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015434587.1 14 Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135 "Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER" XP_015440195.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015436389.1 31 MetaCyc: PWY-8047;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5971;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-4381;MetaCyc: PWY-7723;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;MetaCyc: PWY-8012;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5973;MetaCyc: PWY-7388;MetaCyc: PWY-7664;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5147;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;Reactome: R-HSA-163765 "Bryostatin biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Mupirocin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Oleate biosynthesis I (plants)";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression" XP_015436642.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015439960.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015439884.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_015434717.1 10 Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-111464 "Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_015436521.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-212436;Reactome: R-HSA-1368082 "Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Generic Transcription Pathway";"RORA activates gene expression" XP_015429949.1 15 Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167287 "NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery" XP_015431016.1 3 MetaCyc: PWY-6387;KEGG: 00471+5.1.1.3;MetaCyc: PWY-6386 "UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"D-Glutamine and D-glutamate metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)" XP_015431941.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_015437483.1 6 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-5632684 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state" XP_015437763.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-202433 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules" XP_015429819.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015437083.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015431854.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015428464.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_015430133.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015439719.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_015433320.1 7 MetaCyc: PWY-5084;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Lysine degradation" XP_015439653.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_015432496.1 3 MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57 "Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism" XP_015432598.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015432189.1 17 MetaCyc: PWY-5789;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2 "3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism" XP_015433121.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_015428804.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015430900.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015431353.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_015435405.1 42 Reactome: R-HSA-212300;Reactome: R-HSA-73728;Reactome: R-HSA-3214815;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-171306;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-3214842;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-5625886;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-110329;Reactome: R-HSA-5693565 "PRC2 methylates histones and DNA";"RNA Polymerase I Promoter Opening";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Amyloid fiber formation";"G2/M DNA damage checkpoint";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Packaging Of Telomere Ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"HDMs demethylate histones";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"DNA methylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Cleavage of the damaged pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_015438543.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015430227.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015428454.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015430407.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015432597.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015432103.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015430901.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015428481.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015436591.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015430326.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_015435290.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_015430464.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015432844.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015435725.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015438883.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway" XP_015434480.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015440061.1 57 Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050 "Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_015434111.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015436897.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_015432622.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_015440083.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_015431734.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539 "Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism" XP_015438770.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_015436704.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015432511.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015432235.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination" XP_015439349.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_015436230.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_015428427.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_015437367.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_015433686.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_015439777.1 12 MetaCyc: PWY-7233;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-5873;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5855 "Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_015438576.1 26 Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-6804114;Reactome: R-HSA-6782135;Reactome: R-HSA-69205;Reactome: R-HSA-5358606;Reactome: R-HSA-174417;Reactome: R-HSA-5656121;Reactome: R-HSA-174437;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-1362277;Reactome: R-HSA-4615885;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169 "HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Dual incision in TC-NER";"G1/S-Specific Transcription";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by POLI";"Removal of the Flap Intermediate from the C-strand";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Transcription of E2F targets under negative control by DREAM complex";"SUMOylation of DNA replication proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis" XP_015430421.1 3 Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis" XP_015437096.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015437645.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-1368108 "Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Circadian Clock";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_015438052.1 5 MetaCyc: PWY-6012;MetaCyc: PWY-6012-1;Reactome: R-HSA-199220;MetaCyc: PWY-6289;KEGG: 00770+2.7.8.7 "Acyl carrier protein metabolism";"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism";"Petrobactin biosynthesis";"Pantothenate and CoA biosynthesis" XP_015438506.1 5 MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_015439112.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_015431839.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_015438641.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015435198.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015428848.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015438728.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015439940.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-174084 "Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Hedgehog 'on' state";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_015434766.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015431652.1 7 KEGG: 00550+2.4.1.227;MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6470;Reactome: R-HSA-5633231;MetaCyc: PWY-6385;MetaCyc: PWY-6471 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" XP_015430028.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_015439664.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_015435333.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-8852276 "Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_015430468.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015431724.1 13 MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6969 "Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_015440097.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_015433517.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015439354.1 10 MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-5667;Reactome: R-HSA-1483166 "Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA" XP_015435847.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015438343.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_015439875.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015437648.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_015438558.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015433372.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_015440353.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015439104.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_015432358.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI" XP_015433801.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015433991.1 30 Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-917937;Reactome: R-HSA-5684264;Reactome: R-HSA-400253;Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-187577;Reactome: R-HSA-5610783 "FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Iron uptake and transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Circadian Clock";"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome" XP_015433452.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_015439825.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015432573.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015429418.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962 "Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex" XP_015430754.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_015434221.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_015437207.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_015439071.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_015431912.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_015431588.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015439244.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-176034;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167238 "RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Interactions of Tat with host cellular proteins";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation" XP_015436504.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_015433302.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_015433534.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_015432156.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_015436464.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015429717.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015435635.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015435075.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_015438812.1 29 Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-5696400 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER" XP_015434269.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015433169.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-2565942 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"Regulation of PLK1 Activity at G2/M Transition" XP_015439976.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015428799.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_015436214.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_015440373.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015432563.1 12 MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.3.1;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6613;MetaCyc: PWY-6277;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"One carbon pool by folate";"Purine metabolism";"Biotin transport and metabolism";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_015428672.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015432512.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_015434316.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015433220.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015434481.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936964 "TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_015439264.1 24 Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-163359;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-500657;Reactome: R-HSA-9009391 "Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"G alpha (z) signalling events";"G alpha (s) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon signaling in metabolic regulation";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling" XP_015440276.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription" XP_015436689.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877 "MHC class II antigen presentation";"Aggrephagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase" XP_015437119.1 5 Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24 "Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway" XP_015440358.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015428849.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_015435362.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_015433623.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015431058.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015431783.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_015434322.1 16 Reactome: R-HSA-209543;Reactome: R-HSA-5603037;Reactome: R-HSA-3134963;Reactome: R-HSA-5602680;Reactome: R-HSA-975155;Reactome: R-HSA-6811558;Reactome: R-HSA-166058;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-1257604;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-1810476;Reactome: R-HSA-5602498 "p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 deficiency (TLR5)";"MyD88 dependent cascade initiated on endosome";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Interleukin-1 signaling";"ER-Phagosome pathway";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PIP3 activates AKT signaling";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR2/4)" XP_015440324.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_015430287.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015431472.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015428698.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_015438596.1 14 MetaCyc: PWY-8055;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8053 "Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Synthesis of PE";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis II" XP_015437945.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_015438464.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015438550.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015437463.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_015429668.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_015433716.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015434321.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015435956.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC" XP_015428939.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015440040.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015433541.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015439439.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_015435880.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_015429289.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "DNA replication initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_015435756.1 16 Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593 "TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity" XP_015438876.1 12 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015432979.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_015438990.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015440517.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism";"Thiamine metabolism" XP_015434325.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_015438652.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_015432674.1 5 KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" XP_015429332.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_015435073.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015433262.1 57 Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-532668;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling" XP_015432337.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_015431361.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015431448.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015431123.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015431028.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015437545.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen degradation" XP_015431233.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015440506.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_015440073.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_015432725.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_015430283.1 18 MetaCyc: PWY-5084;Reactome: R-HSA-71064;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00620+1.8.1.4;KEGG: 00260+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-5362517;MetaCyc: PWY-5046;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00380+1.8.1.4 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Signaling by Retinoic Acid";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Tryptophan metabolism" XP_015430597.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_015433438.1 1 Reactome: R-HSA-419771 "Opsins" XP_015430673.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015431519.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015438311.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015430356.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015439955.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex" XP_015431129.1 6 Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III" XP_015439856.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015437395.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015437300.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_015438907.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_015437809.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015436645.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015429352.1 6 MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_015439352.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_015432774.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_015433906.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015434234.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408 "Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation" XP_015433140.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015440014.1 8 Reactome: R-HSA-5083629;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis" XP_015436154.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_015428894.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122 "PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015431969.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122 "Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015439159.1 5 Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-5689877 "Amyloid fiber formation";"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs" XP_015432637.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015431485.1 5 Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39 "Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis" XP_015439259.1 8 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015436581.1 14 KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4 "Linoleic acid metabolism";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism" XP_015437231.1 7 KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14 "Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Drug metabolism - other enzymes" XP_015436564.1 4 Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75 "tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis" XP_015433744.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_015429025.1 4 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_015436873.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015430189.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015429677.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015434405.1 3 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation" XP_015439812.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015439263.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015438001.1 6 MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system" XP_015434528.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015435648.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_015435501.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083 "ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions" XP_015440151.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015438978.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015435977.1 4 Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_015435072.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015434970.1 7 Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268 "Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_015432247.1 12 Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-193692 "Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR" XP_015439776.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_015431445.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015438179.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015431205.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015435160.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015433216.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_015428411.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015431687.1 6 MetaCyc: PWY-7765;MetaCyc: PWY-7717;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-5651;KEGG: 00380+1.14.13.9 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism" XP_015429102.1 15 Reactome: R-HSA-1236382;Reactome: R-HSA-9665251;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-9665233;Reactome: R-HSA-9634285;Reactome: R-HSA-8863795;Reactome: R-HSA-9665246;Reactome: R-HSA-9665245;Reactome: R-HSA-9665247;Reactome: R-HSA-9664565;Reactome: R-HSA-5637810;Reactome: R-HSA-1227986;Reactome: R-HSA-9665250;Reactome: R-HSA-9665244 "Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by Overexpressed ERBB2";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to sapitinib" XP_015435860.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis" XP_015438702.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_015431352.1 3 MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78 "D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" XP_015428739.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_015433391.1 5 MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159 "Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_015438871.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_015432835.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" XP_015440361.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis" XP_015428568.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962 "Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex" XP_015428566.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_015437489.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_015436553.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015439731.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015428970.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616 "Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_015438409.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015436567.1 14 KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7783 "Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation" XP_015438073.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015428735.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015429701.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_015437312.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_015438754.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015432459.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_015439980.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_015439080.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015433008.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015438710.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_015439763.1 11 Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-6782210 "Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015433905.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015431411.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015437558.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015440041.1 6 Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690 "PPARA activates gene expression";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events" XP_015439886.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-193692 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR" XP_015434941.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015429958.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015430887.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015432788.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_015430874.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015438966.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_015435051.1 9 Reactome: R-HSA-5628897;Reactome: R-HSA-5674135;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"MAP2K and MAPK activation";"Macroautophagy";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_015432066.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015440156.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015428470.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015435325.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015433976.1 5 MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis" XP_015429643.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015430091.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015433344.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7589 "Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)" XP_015429482.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015432155.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015432071.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_015436534.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015439013.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015437668.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_015432415.1 9 Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-69205;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"G1/S-Specific Transcription";"Activation of the pre-replicative complex" XP_015434124.1 52 Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-75955;Reactome: R-HSA-203927;Reactome: R-HSA-168325;Reactome: R-HSA-749476 "NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"MicroRNA (miRNA) biogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase III Abortive And Retractive Initiation" XP_015438868.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_015428701.1 4 Reactome: R-HSA-390247;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9 "Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import";"Propanoate metabolism";"beta-Alanine metabolism" XP_015430494.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway" XP_015439797.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_015437022.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_015436744.1 182 Reactome: R-HSA-4608870;Reactome: R-HSA-9646399;Reactome: R-HSA-8876493;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-1169408;Reactome: R-HSA-5696397;Reactome: R-HSA-936440;Reactome: R-HSA-8951664;Reactome: R-HSA-2173788;Reactome: R-HSA-901032;Reactome: R-HSA-5654726;Reactome: R-HSA-450302;Reactome: R-HSA-349425;Reactome: R-HSA-5675482;Reactome: R-HSA-168638;Reactome: R-HSA-1236974;Reactome: R-HSA-69231;Reactome: R-HSA-9637628;Reactome: R-HSA-5654727;Reactome: R-HSA-2691232;Reactome: R-HSA-9013973;Reactome: R-HSA-975956;Reactome: R-HSA-110320;Reactome: R-HSA-912631;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-2408557;Reactome: R-HSA-5357905;Reactome: R-HSA-9014325;Reactome: R-HSA-1358803;Reactome: R-HSA-917729;Reactome: R-HSA-382556;Reactome: R-HSA-5656169;Reactome: R-HSA-6781827;Reactome: R-HSA-9010553;Reactome: R-HSA-5689896;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-8854050;Reactome: R-HSA-5205685;Reactome: R-HSA-9033241;Reactome: R-HSA-168927;Reactome: R-HSA-2565942;Reactome: R-HSA-6782210;Reactome: R-HSA-4641263;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-1253288;Reactome: R-HSA-1799339;Reactome: R-HSA-9613829;Reactome: R-HSA-937042;Reactome: R-HSA-2979096;Reactome: R-HSA-5610783;Reactome: R-HSA-192823;Reactome: R-HSA-3322077;Reactome: R-HSA-5655862;Reactome: R-HSA-936964;Reactome: R-HSA-5675221;Reactome: R-HSA-975957;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-168928;Reactome: R-HSA-6804757;Reactome: R-HSA-937041;Reactome: R-HSA-5357956;Reactome: R-HSA-187577;Reactome: R-HSA-3785653;Reactome: R-HSA-174184;Reactome: R-HSA-6783310;Reactome: R-HSA-6791226;Reactome: R-HSA-5358346;Reactome: R-HSA-5696395;Reactome: R-HSA-917937;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-72695;Reactome: R-HSA-5362768;Reactome: R-HSA-2173795;Reactome: R-HSA-1295596;Reactome: R-HSA-6804756;Reactome: R-HSA-209543;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-6804760;Reactome: R-HSA-2559582;Reactome: R-HSA-72706;Reactome: R-HSA-2672351;Reactome: R-HSA-69541;Reactome: R-HSA-8856825;Reactome: R-HSA-9013507;Reactome: R-HSA-9633012;Reactome: R-HSA-450321;Reactome: R-HSA-69601;Reactome: R-HSA-8856828;Reactome: R-HSA-201681;Reactome: R-HSA-68949;Reactome: R-HSA-445989;Reactome: R-HSA-8948747;Reactome: R-HSA-68827;Reactome: R-HSA-179409;Reactome: R-HSA-532668;Reactome: R-HSA-5689877;Reactome: R-HSA-195253;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975144;Reactome: R-HSA-2644606;Reactome: R-HSA-937039;Reactome: R-HSA-3769402;Reactome: R-HSA-2173791;Reactome: R-HSA-5693607;Reactome: R-HSA-69481;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9636383;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-5654732;Reactome: R-HSA-400253;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-72689;Reactome: R-HSA-8849469;Reactome: R-HSA-3134975;Reactome: R-HSA-8939236;Reactome: R-HSA-110312;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-6807004;Reactome: R-HSA-5607764;Reactome: R-HSA-5693565;Reactome: R-HSA-182971;Reactome: R-HSA-2122947;Reactome: R-HSA-175474;Reactome: R-HSA-2894862;Reactome: R-HSA-6781823;Reactome: R-HSA-162588;Reactome: R-HSA-5685942;Reactome: R-HSA-2559580;Reactome: R-HSA-180534;Reactome: R-HSA-8875360;Reactome: R-HSA-5696394;Reactome: R-HSA-5684264;Reactome: R-HSA-2122948;Reactome: R-HSA-4641258;Reactome: R-HSA-1236382;Reactome: R-HSA-8863795;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-174178;Reactome: R-HSA-156827;Reactome: R-HSA-9645460;Reactome: R-HSA-110314;Reactome: R-HSA-975110;Reactome: R-HSA-174048;Reactome: R-HSA-5696400;Reactome: R-HSA-5654733;Reactome: R-HSA-975163;Reactome: R-HSA-9615710;Reactome: R-HSA-2173796;Reactome: R-HSA-174490;Reactome: R-HSA-2559585;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-6782135;Reactome: R-HSA-205043;Reactome: R-HSA-209560;Reactome: R-HSA-174084;Reactome: R-HSA-5689901;Reactome: R-HSA-5656121;Reactome: R-HSA-8866654 "Asymmetric localization of PCP proteins";"Aggrephagy";"InlA-mediated entry of Listeria monocytogenes into host cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"ISG15 antiviral mechanism";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Negative regulators of DDX58/IFIH1 signaling";"Neddylation";"Downregulation of TGF-beta receptor signaling";"ER Quality Control Compartment (ERQC)";"Negative regulation of FGFR1 signaling";"activated TAK1 mediates p38 MAPK activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of necroptotic cell death";"NOD1/2 Signaling Pathway";"ER-Phagosome pathway";"Cyclin D associated events in G1";"Modulation by Mtb of host immune system";"Negative regulation of FGFR2 signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TICAM1-dependent activation of IRF3/IRF7";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translesion Synthesis by POLH";"Regulation of signaling by CBL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Selenocysteine synthesis";"Regulation of TNFR1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downregulation of ERBB2:ERBB3 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"ABC-family proteins mediated transport";"Termination of translesion DNA synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of expression of SLITs and ROBOs";"Ovarian tumor domain proteases";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Pink/Parkin Mediated Mitophagy";"Peroxisomal protein import";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of PLK1 Activity at G2/M Transition";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of FZD by ubiquitination";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Downregulation of ERBB4 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Chaperone Mediated Autophagy";"IRAK2 mediated activation of TAK1 complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of GLI2 by the proteasome";"Viral mRNA Translation";"Glycogen synthesis";"Translesion synthesis by POLK";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulation of MAPK pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of TP53 Degradation";"IKK complex recruitment mediated by RIP1";"TNFR1-induced NFkappaB signaling pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Myoclonic epilepsy of Lafora";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Fanconi Anemia Pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Hedgehog ligand biogenesis";"Formation of Incision Complex in GG-NER";"Iron uptake and transport";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Formation of the ternary complex, and subsequently, the 43S complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Spry regulation of FGF signaling";"Regulation of TP53 Activity through Phosphorylation";"p75NTR recruits signalling complexes";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of TP53 Activity through Methylation";"Senescence-Associated Secretory Phenotype (SASP)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Stimuli-sensing channels";"Stabilization of p53";"Cargo recognition for clathrin-mediated endocytosis";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Clathrin-mediated endocytosis";"TCF dependent signaling in response to WNT";"Orc1 removal from chromatin";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of PTEN localization";"CDT1 association with the CDC6:ORC:origin complex";"APC-Cdc20 mediated degradation of Nek2A";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Josephin domain DUBs";"Degradation of beta-catenin by the destruction complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"IRAK1 recruits IKK complex";"Deactivation of the beta-catenin transactivating complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Processing of DNA double-strand break ends";"G2/M Checkpoints";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Prevention of phagosomal-lysosomal fusion";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"Negative regulation of FGFR3 signaling";"Circadian Clock";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Separation of Sister Chromatids";"Formation of a pool of free 40S subunits";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of innate immune responses to cytosolic DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Translesion synthesis by REV1";"Regulation of PTEN stability and activity";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Negative regulation of MET activity";"CLEC7A (Dectin-1) signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"EGFR downregulation";"NOTCH1 Intracellular Domain Regulates Transcription";"Assembly Of The HIV Virion";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Formation of TC-NER Pre-Incision Complex";"Budding and maturation of HIV virion";"HDR through Homologous Recombination (HRR)";"Oxidative Stress Induced Senescence";"Vpu mediated degradation of CD4";"InlB-mediated entry of Listeria monocytogenes into host cell";"DNA Damage Recognition in GG-NER";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of DVL";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downregulation of ERBB2 signaling";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translation initiation complex formation";"Peptide chain elongation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"L13a-mediated translational silencing of Ceruloplasmin expression";"Alpha-protein kinase 1 signaling pathway";"Recognition of DNA damage by PCNA-containing replication complex";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Dual Incision in GG-NER";"Negative regulation of FGFR4 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Late endosomal microautophagy";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Membrane binding and targetting of GAG proteins";"Oncogene Induced Senescence";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Dual incision in TC-NER";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival";"Autodegradation of Cdh1 by Cdh1:APC/C";"Metalloprotease DUBs";"Translesion synthesis by POLI";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015434579.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_015434662.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015429085.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015436860.1 7 Reactome: R-HSA-201688;Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258 "WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Degradation of DVL" XP_015435695.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-111465;Reactome: R-HSA-176187 "Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress" XP_015439507.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015434620.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_015435999.1 24 Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-8955332 "Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin" XP_015434668.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_015434131.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015438935.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_015432985.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_015435473.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015439997.1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism" XP_015436712.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_015433791.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015439412.1 4 KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis" XP_015437299.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_015435304.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015429405.1 3 MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456 "Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid" XP_015434575.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_015431700.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015439384.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_015431887.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_015437211.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015431206.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_015439174.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_015431583.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_015435636.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015439252.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_015429581.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015431707.1 6 KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism" XP_015434879.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_015433315.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-381038 "Protein ubiquitination";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes" XP_015437734.1 4 Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356 "Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_015431504.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_015434429.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_015430573.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_015429293.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_015439756.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_015435427.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_015438276.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015429241.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015431621.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_015436551.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015433383.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015431509.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015430572.1 10 MetaCyc: PWY-7199;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-3841;Reactome: R-HSA-69205;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;KEGG: 00670+2.1.1.45 "Pyrimidine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"One carbon pool by folate" XP_015429238.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_015440364.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_015437121.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015439029.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015435031.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015432898.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015434046.1 24 Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"MHC class II antigen presentation";"Recycling pathway of L1";"Mitotic Prometaphase";"Cilium Assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" XP_015432858.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_015430672.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16 "Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" XP_015438081.1 11 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1834949 "Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"Cytosolic sensors of pathogen-associated DNA" XP_015437284.1 11 Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_015430269.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015433227.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-139915 "TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria" XP_015428862.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_015431319.1 8 Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Activation of RAC1";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_015430583.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015434761.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015434106.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_015436103.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis" XP_015435588.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_015429978.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015436398.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_015438498.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015432354.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_015430703.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497 "Recycling pathway of L1";"MHC class II antigen presentation";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_015433829.1 5 KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532 "Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)" XP_015431140.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus" XP_015430749.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015428935.1 22 MetaCyc: PWY-7724;MetaCyc: PWY-7726;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7602;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7606 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" XP_015431639.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015437824.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015435167.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-174178 "Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015439177.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015438845.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015439404.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015430838.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_015432246.1 12 Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948 "Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_015435579.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015436172.1 13 Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902 "Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)" XP_015436840.1 17 Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-9616222;Reactome: R-HSA-111448;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-2559585 "Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"Transcriptional regulation of granulopoiesis";"Activation of NOXA and translocation to mitochondria";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"Oncogene Induced Senescence" XP_015434767.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015437325.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015437324.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_015438119.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015436252.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_015434967.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-381426 "LDL remodeling";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Chylomicron assembly";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"VLDL assembly";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Chylomicron remodeling";"VLDL clearance";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_015433599.1 14 Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400 "Translesion Synthesis by POLH";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER" XP_015438691.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation" XP_015435448.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_015435096.1 17 KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5392;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;KEGG: 00680+1.1.1.37 "Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methane metabolism" XP_015436930.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015429294.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_015439106.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258 "MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL" XP_015440416.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_015434416.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015430472.1 15 Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5467348 "T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex" XP_015439063.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_015434027.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015431862.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015438834.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015436557.1 6 Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;MetaCyc: PWY-6854 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)" XP_015437570.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_015429552.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis" XP_015428729.1 7 KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8 "Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism" XP_015436266.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015429991.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_015438800.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015438461.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" XP_015436896.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_015439951.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_015433780.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_015433119.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_015428683.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_015439694.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_015431858.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_015437874.1 15 KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40 "Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Purine metabolism" XP_015438008.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_015430995.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_015439353.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053 "Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II" XP_015433965.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015434748.1 10 Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-111464 "Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_015435452.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015435003.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neutrophil degranulation";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL" XP_015431211.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015439128.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015428828.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015432905.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015438701.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015439376.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015437339.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015434558.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015437555.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_015432110.1 9 KEGG: 00350+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Tyrosine catabolism" XP_015440402.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_015438575.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_015433696.1 4 MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_015431355.1 4 MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_015435805.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_015440502.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015439638.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_015440028.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_015433477.1 11 Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-6804756 "Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation" XP_015439622.1 7 Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism" XP_015428455.1 3 KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695 "Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation" XP_015439779.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_015431983.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015435766.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015428881.1 5 Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111464 "Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_015429075.1 9 MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_015438471.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015439860.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_015428743.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_015438107.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition" XP_015433163.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946 "Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants" XP_015433034.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015439133.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015436257.1 56 Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780 "Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome" XP_015440168.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Iron uptake and transport";"UCH proteinases";"TGF-beta receptor signaling activates SMADs" XP_015437775.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015438676.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015428792.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_015438349.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015433382.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015432896.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015431204.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015435309.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015437757.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015431250.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_015431972.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015430521.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015431072.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015433041.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702 "Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling" XP_015432049.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015432033.1 4 KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_015434446.1 17 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_015431632.1 14 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-399997;MetaCyc: PWY-7039;Reactome: R-HSA-500657;MetaCyc: PWY-8052;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-1855204;Reactome: R-HSA-4086398;KEGG: 00562+3.1.4.11;Reactome: R-HSA-434316 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Synthesis of IP3 and IP4 in the cytosol";"Ca2+ pathway";"Inositol phosphate metabolism";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_015436293.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" XP_015433734.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_015432024.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_015434374.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015437344.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_015434357.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015436003.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_015438288.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_015433335.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_015435360.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_015440336.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257 "Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion" XP_015437477.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015429566.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015432302.1 3 Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709 "Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" XP_015437777.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_015434198.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_015432561.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015438236.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015431896.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_015434503.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_015434294.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015437656.1 8 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015439053.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015430676.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_015439438.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis" XP_015428404.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_015440053.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_015436758.1 12 MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861 "Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_015430050.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015438060.1 5 MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7177 "UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II" XP_015435477.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_015437155.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_015440090.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276 "Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_015428749.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015437132.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015435536.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Interleukin-1 signaling";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of AXIN";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling" XP_015438693.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015439726.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015430482.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015440476.1 60 KEGG: 00310+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00410+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00380+4.2.1.17;KEGG: 00650+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77288;MetaCyc: PWY-6863;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6945;MetaCyc: PWY-6946;Reactome: R-HSA-77348;MetaCyc: PWY-7216;KEGG: 00280+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7726;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7007;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5177;MetaCyc: PWY-7606;KEGG: 00627+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;MetaCyc: PWY-1361;Reactome: R-HSA-77346;KEGG: 00362+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6583;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-7778;Reactome: R-HSA-77305;Reactome: R-HSA-1482798;MetaCyc: PWY-6435;Reactome: R-HSA-77350;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285 "Lysine degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Carbon fixation pathways in prokaryotes";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"beta-Alanine metabolism";"Propanoate metabolism";"Benzoate degradation";"Caprolactam degradation";"Phenylalanine metabolism";"Tryptophan metabolism";"Butanoate metabolism";"Butanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Fatty acid degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid elongation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"Methyl ketone biosynthesis (engineered)";"Fatty acid elongation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid salvage";"Butanoate metabolism";"Androstenedione degradation";"Glutaryl-coa degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Aminobenzoate degradation";"Tryptophan metabolism";"Geraniol degradation";"Geraniol degradation";"Benzoyl-coa degradation I (aerobic)";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Benzoate degradation";"Caprolactam degradation";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"Limonene and pinene degradation";"Fermentation to 2-methylbutanoate";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"2-methylpropene degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Acyl chain remodeling of CL";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"alpha-Linolenic acid metabolism";"Lysine degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA" XP_015436010.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_015431664.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_015432419.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015432925.1 6 KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_015434863.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015437725.1 20 Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-165159;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-166208 "Macroautophagy";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"Thermogenesis";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Human immunodeficiency virus 1 infection";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling" XP_015438999.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015435169.1 4 MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583 "Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)" XP_015428766.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_015430736.1 4 Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_015430843.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_015432868.1 14 Reactome: R-HSA-2173788;Reactome: R-HSA-5687128;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813 "Downregulation of TGF-beta receptor signaling";"MAPK6/MAPK4 signaling";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids" XP_015436137.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660 "G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway" XP_015431496.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription" XP_015436394.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015432952.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_015434219.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015439163.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_015439012.1 11 Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility" XP_015432702.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015440004.1 14 MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Sciadonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_015439178.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015437062.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_015437723.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-1169408 "tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism" XP_015432722.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_015431833.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015436336.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015430477.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015435777.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015433694.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_015437498.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015430267.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_015428978.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015436547.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_015433697.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_015434244.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015435020.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015435283.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_015430658.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015435439.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_015437258.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015435449.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_015433191.1 17 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015430782.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_015429544.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin" XP_015428544.1 4 Reactome: R-HSA-947581;Reactome: R-HSA-1362409;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" XP_015434137.1 7 Reactome: R-HSA-74217;MetaCyc: PWY-7807;MetaCyc: PWY-6610;MetaCyc: PWY-6605;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805 "Purine salvage";"Glyphosate degradation III";"Adenine salvage";"Adenine and adenosine salvage II";"Neutrophil degranulation";"Purine metabolism";"(aminomethyl)phosphonate degradation" XP_015439944.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease" XP_015429745.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015430436.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_015429135.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_015434195.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_015432967.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015439835.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_015430509.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015434975.1 4 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_015428487.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015431801.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015432917.1 5 Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015433816.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_015440498.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_015438875.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015431809.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_015436533.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015437368.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015432261.1 13 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-1474244 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils";"ECM proteoglycans";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Anchoring fibril formation";"NCAM1 interactions";"Extracellular matrix organization" XP_015432046.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_015430707.1 16 Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176408 "Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase" XP_015440327.1 6 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_015434205.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_015437756.1 28 Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-68962;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5696395;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-5358606 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"HSF1 activation";"Activation of the pre-replicative complex";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Meiotic recombination";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_015430687.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015436725.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015438867.1 12 Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015433100.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015430137.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821 "Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification" XP_015436498.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_015431044.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_015434101.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015437830.1 58 Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5689901;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-2871837 "Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Metalloprotease DUBs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation" XP_015438315.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015429821.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015436178.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015433267.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015430677.1 33 MetaCyc: PWY-7013;MetaCyc: PWY-3162;MetaCyc: PWY-5082;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6802;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-7396;MetaCyc: PWY-7111;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5078;MetaCyc: PWY-5076;Reactome: R-HSA-71384;KEGG: 00680+1.1.1.284;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-5480;MetaCyc: PWY-5057;MetaCyc: PWY-6342;KEGG: 00071+1.1.1.1;MetaCyc: PWY-1801;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-5486;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7798;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5751 "(S)-propane-1,2-diol degradation";"L-tryptophan degradation V (side chain pathway)";"L-methionine degradation III";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol III";"Glycolysis / Gluconeogenesis";"Salidroside biosynthesis";"Retinol metabolism";"Serotonin degradation";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"Glycine, serine and threonine metabolism";"L-isoleucine degradation II";"L-leucine degradation III";"Ethanol oxidation";"Methane metabolism";"Metabolism of xenobiotics by cytochrome P450";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol I";"L-valine degradation II";"Noradrenaline and adrenaline degradation";"Fatty acid degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Drug metabolism - cytochrome P450";"Acetaldehyde biosynthesis I";"Tyrosine metabolism";"L-phenylalanine degradation III";"Pyruvate fermentation to ethanol II";"alpha-Linolenic acid metabolism";"Protein S-nitrosylation and denitrosylation";"Naphthalene degradation";"Chitin degradation to ethanol";"Phenylethanol biosynthesis" XP_015436334.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015430046.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_015438058.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_015434292.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015431855.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_015436468.1 10 Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644 "EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Inhibition of membrane repair" XP_015435596.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015439790.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_015438751.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_015437480.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-6784531 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus" XP_015438911.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_015431084.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_015438125.1 57 Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-532668 "Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_015433571.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_015431586.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_015428805.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_015431988.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_015435426.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015433546.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015432933.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015436344.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_015437549.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_015435416.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis" XP_015428984.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889 "CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes" XP_015434534.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_015436112.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_015430470.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015433761.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-6807878 "Aggrephagy";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport" XP_015439369.1 4 MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II" XP_015437783.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015437554.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015430023.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_015434166.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_015433548.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015436572.1 3 KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_015429355.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015438455.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_015437351.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015435268.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_015437877.1 18 MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_015429872.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015437884.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015438680.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099 "Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling" XP_015437575.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015437844.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015438805.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73779 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_015430359.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015439770.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015437893.1 33 Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-69656;Reactome: R-HSA-6782210;Reactome: R-HSA-8939236;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-427413 "Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin A:Cdk2-associated events at S phase entry";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression" XP_015430274.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Fatty acid elongation";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_015436023.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_015433884.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015431142.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-198323 "HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"mTOR signalling";"AKT phosphorylates targets in the cytosol" XP_015432726.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_015429389.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation" XP_015435806.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015432408.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015435162.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_015429669.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015431541.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202 "Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition" XP_015438230.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015436848.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015429351.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;MetaCyc: PWY-7511 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination" XP_015435406.1 10 MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11 "L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism" XP_015433730.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_015435708.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_015439580.1 8 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by Hippo";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015438219.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_015431768.1 3 MetaCyc: PWY-5996;MetaCyc: PWY-5987;Reactome: R-HSA-75105 "Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis" XP_015433256.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015432627.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015428511.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Chylomicron remodeling";"LDL clearance";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Scavenging by Class H Receptors" XP_015436549.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_015440520.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015438574.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015438206.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015430299.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015439258.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_015436568.1 14 Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4 "Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Linoleic acid metabolism" XP_015439440.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_015438013.1 5 MetaCyc: PWY-6906;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855 "Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)" XP_015432931.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015437871.1 15 Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-7218;MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-5723 "Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt" XP_015440406.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015439773.1 4 Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015430953.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_015435460.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015432320.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015434574.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201 "Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_015430441.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_015439119.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA" XP_015432587.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015433700.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015429078.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015430010.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_015439618.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_015428505.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015438203.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015434026.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_015436530.1 4 Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_015432215.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_015429868.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015439720.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015435322.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015436828.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015435429.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015430883.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015437346.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015438479.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924 "MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport" XP_015437297.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_015431557.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015437030.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015440039.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_015439577.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015428633.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015440491.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168325 "Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis" XP_015428695.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_015428605.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015433511.1 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17 "Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Caprolactam degradation" XP_015439739.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_015435255.1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_015439700.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015430301.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015435133.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_015431924.1 29 Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-6781827 "Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_015439995.1 6 Reactome: R-HSA-6811440;Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Insulin processing";"VxPx cargo-targeting to cilium";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intra-Golgi traffic" XP_015431061.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_015432761.1 7 KEGG: 00970+6.1.1.15;MetaCyc: PWY-5188;Reactome: R-HSA-379716;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism" XP_015433524.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015430784.1 12 Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606 "Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015434095.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_015434741.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway" XP_015434428.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_015439132.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_015433425.1 5 MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667 "CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I" XP_015429607.1 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_015431089.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_015435857.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport" XP_015439788.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_015429718.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015432296.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_015436922.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-7328 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose catabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_015439841.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_015438949.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_015433550.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015435731.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_015430032.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_015431033.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015436996.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015435358.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation" XP_015439858.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Glyoxylate assimilation" XP_015436682.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_015439075.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015429710.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_015438912.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_015439659.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_015431891.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015433687.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_015429921.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_015431032.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015432232.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_015429617.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015433186.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_015430110.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015428762.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_015433141.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_015433699.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015440176.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015432976.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346 "ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis" XP_015430778.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015430174.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015429746.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_015428751.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015440051.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_015436077.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_015432501.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_015430492.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015438292.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_015437739.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168 "Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Circadian Clock";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)" XP_015438884.1 33 Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-191859 "Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly" XP_015429017.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)" XP_015429869.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_015439094.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_015431296.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_015432775.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_015429175.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015432240.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_015433994.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015430836.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015429225.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015436177.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_015435227.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015434664.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015432514.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015429086.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015440414.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015436640.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015429804.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015435420.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015437557.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015433781.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015439422.1 26 Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-190840 "EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Cilium Assembly";"Recycling pathway of L1";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_015437895.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_015432162.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" XP_015439319.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_015433480.1 7 Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_015428571.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_015436264.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_015439370.1 3 Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_015430614.1 4 Reactome: R-HSA-156581;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315 "Methylation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol" XP_015428504.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015439337.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_015438836.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_015434694.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_015430070.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015433775.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015436466.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685 "Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy" XP_015438667.1 42 KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7656;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-6883;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6946;MetaCyc: PWY-6863;MetaCyc: PWY-6945;KEGG: 00623+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7779;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-1361;MetaCyc: PWY-7606;KEGG: 00627+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5177;KEGG: 00592+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-7778;MetaCyc: PWY-7654 "Fatty acid degradation";"Butanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"beta-Alanine metabolism";"Propanoate metabolism";"Benzoate degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid salvage";"Butanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Toluene degradation";"Limonene and pinene degradation";"Fermentation to 2-methylbutanoate";"Methyl tert-butyl ether degradation";"Caprolactam degradation";"Pyruvate fermentation to butanol I";"Benzoyl-coa degradation I (aerobic)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Aminobenzoate degradation";"Tryptophan metabolism";"Geraniol degradation";"Androstenedione degradation";"Glutaryl-coa degradation";"alpha-Linolenic acid metabolism";"Lysine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis" XP_015432418.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_015434776.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015437797.1 4 Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144 "Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" XP_015433235.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_015437639.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_015436300.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015439612.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015432264.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_015433392.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827 "Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_015435980.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015429495.1 10 KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"Sphingolipid metabolism";"HS-GAG degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series" XP_015432085.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_015429661.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_015440243.1 22 Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221 "Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway" XP_015430271.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00010+2.7.2.3 "Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_015438564.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975;MetaCyc: PWY-7282 "Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_015430264.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_015438612.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_015431681.1 6 Reactome: R-HSA-977347;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52 "Serine biosynthesis";"Methane metabolism";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism" XP_015429866.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_015434352.1 5 KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_015438513.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-5981;MetaCyc: PWY-7589 "Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)" XP_015430719.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015430312.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_015431429.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_015434737.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_015436063.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015433577.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_015439584.1 17 Reactome: R-HSA-6798695;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-6608;Reactome: R-HSA-74217;Reactome: R-HSA-74259;MetaCyc: PWY-6620;MetaCyc: PWY-6611;MetaCyc: PWY-5532 "Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Purine salvage";"Purine catabolism";"Guanine and guanosine salvage";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)" XP_015439228.1 17 Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-3270619;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-1834949;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"IRF3-mediated induction of type I IFN";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Cytosolic sensors of pathogen-associated DNA";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)" XP_015434284.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_015439030.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015436851.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015438357.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015435840.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015432158.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_015433022.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015440220.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015432372.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015439261.1 13 Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-975163;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-937042 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex" XP_015432126.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015439492.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015439444.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015437371.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_015434618.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_015435520.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_015429174.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_015429551.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015433370.1 11 MetaCyc: PWY-5381;MetaCyc: PWY-6607;MetaCyc: PWY-7821;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5 "Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Purine metabolism" XP_015431349.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_015428620.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_015436715.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_015433021.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015433547.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015430157.1 25 Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-381771;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-400042 "G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion" XP_015432439.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_015439696.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" XP_015428892.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_015433371.1 11 KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6608;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-7821;MetaCyc: PWY-6596;MetaCyc: PWY-5381;MetaCyc: PWY-6607 "Purine metabolism";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Tunicamycin biosynthesis";"Adenosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I" XP_015432909.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_015428467.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_015428548.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_015429365.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_015438158.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015429169.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015430706.1 24 Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148 "Aggrephagy";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015432175.1 3 MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade" XP_015433750.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_015437806.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_015431711.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015428920.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015429979.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_015432441.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015435232.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_015439932.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015438279.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_015438468.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_015431194.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015429453.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_015434165.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_015430955.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_015432169.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015438678.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_015430895.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015439061.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_015435296.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Activation of RAC1" XP_015432643.1 7 KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism" XP_015439757.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_015437803.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015433089.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015438533.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123 "Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" XP_015434974.1 4 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_015433050.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_015429971.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015435567.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015434193.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015438376.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015431120.1 6 Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922 "Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium" XP_015433283.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_015437340.1 11 MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7124 "Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)" XP_015436791.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015432402.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_015437041.1 20 Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-176187 "Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress" XP_015437714.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015436374.1 9 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection" XP_015439417.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015437257.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015428985.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015429372.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015437553.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015431152.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015434028.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_015431933.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_015428795.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015439245.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-176034;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-167243;Reactome: R-HSA-167290 "Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation" XP_015432174.1 3 MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade" XP_015434314.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_015433867.1 2 KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_015433645.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243 "Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Neutrophil degranulation";"Synthesis of PC";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_015432765.1 7 MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6724;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695 "Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation II";"Glycogen degradation II";"Starch and sucrose metabolism";"Neutrophil degranulation" XP_015437005.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_015434493.1 9 KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_015429909.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015430427.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_015433486.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015432987.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_015431220.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015429642.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_015435505.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_015435411.1 42 Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-3214815;Reactome: R-HSA-73728;Reactome: R-HSA-212300;Reactome: R-HSA-3214842;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-201722;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-1221632;Reactome: R-HSA-5250924;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-5625886;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-3214858;Reactome: R-HSA-5693565;Reactome: R-HSA-110329;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-2559582;Reactome: R-HSA-606279 "Amyloid fiber formation";"G2/M DNA damage checkpoint";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"HDACs deacetylate histones";"RNA Polymerase I Promoter Opening";"PRC2 methylates histones and DNA";"HDMs demethylate histones";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"HCMV Late Events";"Meiotic synapsis";"B-WICH complex positively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RMTs methylate histone arginines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged pyrimidine";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_015434246.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015435223.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015429719.1 4 KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)" XP_015430881.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015435230.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015432778.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015438708.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" XP_015428624.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_015428879.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015432592.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080 "Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)" XP_015429461.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015438923.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015437702.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_015435237.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-190873 "Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation" XP_015440104.1 4 KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)" XP_015435254.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_015429625.1 19 Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-8963901;Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828 "Chylomicron clearance";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"VLDL clearance";"LDL clearance";"Chylomicron remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class F Receptors";"VLDL assembly";"Clathrin-mediated endocytosis" XP_015428468.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_015433026.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_015436698.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015438233.1 3 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation" XP_015437794.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039 "Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex" XP_015428572.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_015435365.1 5 KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37 "Glycine, serine and threonine metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" XP_015433912.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015433894.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015432048.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015436045.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_015433249.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_015432457.1 7 Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67 "Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism" XP_015439993.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015432515.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_015438976.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_015439058.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015431301.1 5 KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427 "Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"SUMOylation of DNA methylation proteins" XP_015435506.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_015435864.1 9 Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809 "FCERI mediated MAPK activation";"Rho GTPase cycle";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization" XP_015432837.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_015435349.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015431073.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015429362.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015429237.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_015435103.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558 "S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_015429227.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015435431.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015428821.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation" XP_015439947.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015435174.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_015433035.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015437767.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-73614;MetaCyc: PWY-6556;MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5 "Neutrophil degranulation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" XP_015435600.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015431970.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_015434472.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015433420.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_015434788.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015428546.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism" XP_015434191.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015436302.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015435668.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_015438601.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015431118.1 5 KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-6692 "Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation" XP_015434183.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015440200.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015430692.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_015437469.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_015435517.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015436587.1 8 MetaCyc: PWY-5269;KEGG: 04658+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817 "Cardiolipin biosynthesis II";"Th1 and Th2 cell differentiation";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_015429385.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015439813.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015435150.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015439715.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_015433783.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015431615.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_015440095.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015430192.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015433352.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471 "Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response" XP_015436531.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_015436540.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793 "RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis" XP_015439740.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_015438462.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_015435323.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015432494.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015430590.1 9 Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5484 "Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)" XP_015436688.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Aggrephagy";"MHC class II antigen presentation" XP_015440046.1 8 Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579 "Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange" XP_015428864.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015440378.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015435987.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168325 "Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"HCMV Early Events";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis" XP_015438172.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015435516.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015438358.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_015433685.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_015435798.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_015436503.1 5 Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413 "SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression" XP_015438504.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_015439887.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_015440164.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015440263.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_015438019.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015434090.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_015438906.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015430107.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_015432042.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_015436635.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015429089.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_015440047.1 10 Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5839;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-7996;MetaCyc: PWY-5844;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895 "Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis" XP_015435399.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_015432052.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" XP_015430145.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_015437036.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015429890.1 13 KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18 "Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450" XP_015437843.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015429417.1 4 KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4 "Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism" XP_015435893.1 15 Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-6796648 "Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes" XP_015437813.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015434803.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68689 "Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex" XP_015439418.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_015429006.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_015428856.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_015431943.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015433999.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_015439284.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)" XP_015440002.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015431559.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_015430710.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_015434104.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_015432904.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170 "ECM proteoglycans";"Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions" XP_015435659.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015438869.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_015436444.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1" XP_015436397.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_015435013.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_015437126.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015430923.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015438446.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_015431497.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_015432964.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015431371.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation" XP_015428987.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_015429941.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_015437439.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015434112.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015439568.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015436969.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18 "Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism" XP_015432267.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_015437796.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039 "Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex" XP_015432479.1 8 KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-5659996;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6 "Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P";"Rubisco shunt";"Pentose phosphate pathway";"Fructose and mannose metabolism" XP_015435701.1 3 Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361 "Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins" XP_015432190.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015428988.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809 "Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Regulation of insulin secretion";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization" XP_015439565.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" XP_015433028.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015433789.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_015429506.1 4 MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_015433520.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015440481.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_015438497.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_015429069.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015433165.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695 "Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation" XP_015428954.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638 "NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins" XP_015438061.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_015429806.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015436254.1 2 MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_015435457.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015435175.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015432678.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174 "Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_015433340.1 17 Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-5689880;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091 "Ca2+ pathway";"Interleukin-1 signaling";"Downstream TCR signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"Ub-specific processing proteases";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells" XP_015428527.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_015432943.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015437035.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015439874.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_015432863.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015431227.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015434201.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_015432686.1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880 "Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases" XP_015429728.1 5 Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756;Reactome: R-HSA-936440 "ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling" XP_015430370.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015437182.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Activation of RAC1";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015439844.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015437091.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015434456.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_015437301.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_015434991.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_015433036.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015436105.1 18 Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-6804756;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750 "TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Protein ubiquitination";"Regulation of TP53 Activity through Phosphorylation";"Meiotic synapsis";"Meiotic recombination";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6" XP_015438407.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_015433721.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" XP_015431170.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015428733.1 5 KEGG: 00230+3.6.1.6;MetaCyc: PWY-7210;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185 "Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I" XP_015436375.1 9 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway" XP_015430656.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015432412.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_015435719.1 7 MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25 "Phytate degradation I";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Inositol phosphate metabolism" XP_015431137.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_015430519.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_015428551.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015432433.1 13 MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_015437072.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_015431844.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_015432275.1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-211733;Reactome: R-HSA-5687128 "Degradation of DVL";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling" XP_015430409.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015430016.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_015429558.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_015438465.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_015432717.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis" XP_015431442.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_015429507.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_015429172.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_015438049.1 9 MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7115 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_015439787.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015431511.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015430388.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_015439902.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015436111.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_015435663.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_015435563.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015430811.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-9620244 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"RAF activation";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation" XP_015429113.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_015433287.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_015431626.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015435521.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_015428528.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015429467.1 11 KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Purine metabolism" XP_015440322.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_015436443.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_015437801.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015433316.1 5 Reactome: R-HSA-381038;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;MetaCyc: PWY-7511 "XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"Protein ubiquitination" XP_015434670.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_015437870.1 15 MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-7383;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901 "Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation" XP_015429733.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_015440029.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015429033.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015434977.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_015429545.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_015435876.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015430731.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_015433435.1 10 MetaCyc: PWY-6365;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855204;Reactome: R-HSA-983231;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;MetaCyc: PWY-6366;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.159 "D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system" XP_015433250.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015438833.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_015432326.1 11 MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5154;MetaCyc: PWY-7790 "UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis II" XP_015428670.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_015430257.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015432153.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_015432838.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_015429176.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015435765.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015433104.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_015437591.1 3 Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-70263 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Gluconeogenesis" XP_015432650.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015436775.1 3 KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_015435778.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015437031.1 11 Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615 "G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation" XP_015439798.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015430755.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_015439751.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015430111.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015437597.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_015428774.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_015436416.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_015433226.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167242 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_015439064.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_015433072.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_015433838.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_015436265.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015438156.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_015440405.1 42 Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-5617472;Reactome: R-HSA-110329;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-8939236;Reactome: R-HSA-3214841;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-4551638;Reactome: R-HSA-5693571;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-5625886;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-201722;Reactome: R-HSA-427359;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-5693607;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-73728 "Transcriptional regulation by small RNAs";"DNA methylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PKMTs methylate histone lysines";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"SUMOylation of chromatin organization proteins";"Nonhomologous End-Joining (NHEJ)";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"Formation of the beta-catenin:TCF transactivating complex";"SIRT1 negatively regulates rRNA expression";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Processing of DNA double-strand break ends";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"Amyloid fiber formation";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"RNA Polymerase I Promoter Opening" XP_015437838.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_015436657.1 8 MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27 "Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Propanoate metabolism" XP_015431218.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_015430498.1 5 KEGG: 04070+3.1.3.64;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660499;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation" XP_015428653.1 7 Reactome: R-HSA-196757;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;Reactome: R-HSA-69205;Reactome: R-HSA-1474151 "Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"Folate transformations II (plants)";"One carbon pool by folate";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_015439165.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015433891.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_015428396.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_015440514.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015430462.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015433674.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015429088.1 6 Reactome: R-HSA-8951664;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402 "Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex" XP_015440163.1 52 Reactome: R-HSA-749476;Reactome: R-HSA-203927;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-75953;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-167162;Reactome: R-HSA-427413 "RNA Polymerase III Abortive And Retractive Initiation";"MicroRNA (miRNA) biogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Capping";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression" XP_015440072.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_015428951.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_015438758.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_015431101.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015439350.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_015438879.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_015432620.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_015432558.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015433880.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015433810.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015440003.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015437720.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_015434320.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_015438147.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471 "Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB" XP_015428827.1 12 MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Stachyose degradation" XP_015437410.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015436885.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015433679.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus" XP_015438095.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015430834.1 18 MetaCyc: PWY-5913;Reactome: R-HSA-70263;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-561;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-6969 "Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_015437321.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_015437831.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Unwinding of DNA" XP_015438819.1 10 Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153 "Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Inositol phosphate metabolism";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system" XP_015436835.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_015434735.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015439453.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015429353.1 7 Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_015438690.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_015440089.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_015437459.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_015433876.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015440060.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015437397.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015432695.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258 "MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL" XP_015436002.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_015436151.1 8 MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_015433684.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015435372.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015438934.1 3 KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism" XP_015429302.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_015436497.1 6 MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790 "UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II" XP_015433702.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015436750.1 3 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import" XP_015439619.1 3 Reactome: R-HSA-2151201;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "Transcriptional activation of mitochondrial biogenesis";"UCH proteinases";"HATs acetylate histones" XP_015437227.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-6978;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872;MetaCyc: PWY-5856 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_015435222.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015431080.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_015433424.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_015431108.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_015438129.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015435267.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015440359.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_015430885.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_015436469.1 10 Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-917729 "InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"Inhibition of membrane repair";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_015439169.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015440403.1 17 Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-69183;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Processive synthesis on the lagging strand";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER" XP_015432471.1 17 KEGG: 05163+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-75035;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-6796648;Reactome: R-HSA-8953750;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-6804756 "Human cytomegalovirus infection";"Signaling by SCF-KIT";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Processing of DNA double-strand break ends";"Thermogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional Regulation by E2F6";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation" XP_015435865.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_015428867.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_015436652.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex" XP_015436207.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_015438885.1 12 Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Translation initiation complex formation";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_015429037.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015439300.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015428838.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_015431773.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015439374.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015431027.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015432038.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015435148.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_015433419.1 16 Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-5693548 "Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"HATs acetylate histones";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks" XP_015438827.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-70268 "Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_015429123.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_015432338.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_015440348.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015429715.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015428717.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_015439292.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_015433977.1 5 MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism" XP_015439801.1 19 Reactome: R-HSA-428543;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-8964616;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;Reactome: R-HSA-5663220;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-5627123;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-2029482 "Inactivation of CDC42 and RAC1";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"EGFR downregulation";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"G beta:gamma signalling through CDC42";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"EPHB-mediated forward signaling";"RHO GTPases Activate Formins";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate PAKs";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation" XP_015436656.1 16 Reactome: R-HSA-70171;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-7124;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1622;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-7218;MetaCyc: PWY-6901;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-2221 "Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation I (serine pathway)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_015428555.1 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_015429267.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015437832.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015431424.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015437437.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015430613.1 5 KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III" XP_015437448.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015432565.1 14 MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7279;Reactome: R-HSA-71403;MetaCyc: PWY-6969 "TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_015439459.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_015435089.1 29 Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-113418 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of the Early Elongation Complex" XP_015431413.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_015428836.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015434740.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015439392.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_015432781.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036 "Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_015439130.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015433515.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_015439410.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015433078.1 6 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3" XP_015435291.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594 "PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events" XP_015428619.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_015439468.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015433503.1 12 MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-7233;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5856 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_015431779.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015437097.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_015436098.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015430908.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_015432696.1 56 Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5689880 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Neddylation";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Interleukin-1 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases" XP_015431602.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_015440250.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_015439078.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_015429153.1 4 KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268 "Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_015435418.1 16 Reactome: R-HSA-1257604;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-512988;Reactome: R-HSA-8853659 "PIP3 activates AKT signaling";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling" XP_015435869.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015439262.1 2 MetaCyc: PWY-6163;KEGG: 00400+2.5.1.19 "Chorismate biosynthesis from 3-dehydroquinate";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_015433910.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015438640.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_015432012.1 8 Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis" XP_015432077.1 17 MetaCyc: PWY-561;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7115;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37 "Superpathway of glyoxylate cycle and fatty acid degradation";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes" XP_015429397.1 3 MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456 "Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid" XP_015435039.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015432870.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-69273;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Cyclin A/B1/B2 associated events during G2/M transition";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins" XP_015438830.1 7 Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-168333 "tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_015438029.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015430992.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_015429137.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015436009.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015432899.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015431859.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015432924.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_015434862.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_015436755.1 5 MetaCyc: PWY-6129;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;Reactome: R-HSA-4755579 "Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ" XP_015439041.1 20 Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110312 "Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLK";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1" XP_015436670.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_015428753.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015432680.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_015435786.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_015439562.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015435055.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_015431388.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015439698.1 19 Reactome: R-HSA-3000471;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888 "Scavenging by Class B Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"Chylomicron clearance";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"VLDL clearance";"Chylomicron remodeling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"LDL remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Chylomicron assembly" XP_015436208.1 13 MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916 "Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation" XP_015437715.1 57 Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-8939236 "Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_015440363.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_015430909.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_015440419.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015432196.1 14 Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-6798695;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neutrophil degranulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3" XP_015436951.1 12 Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-75955 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation" XP_015428532.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015436813.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_015433549.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015436637.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015428832.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_015432576.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-6842 "Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II" XP_015438746.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_015429354.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015430273.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_015437966.1 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780 "Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome" XP_015434470.1 13 KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;MetaCyc: PWY-6842;Reactome: R-HSA-156590;Reactome: R-HSA-196836;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1 "Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism" XP_015431277.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_015429969.1 24 Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-8964616;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-428930 "G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G beta:gamma signalling through CDC42";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor" XP_015432283.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_015430812.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571 "Interferon gamma signaling";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"RAF activation";"HSF1-dependent transactivation" XP_015429957.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015439965.1 9 Reactome: R-HSA-110357;Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-9657050;Reactome: R-HSA-5649702 "Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Localization";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_015428513.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015432445.1 6 Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_015434645.1 3 Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271 "GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_015436998.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015438499.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_015429445.1 9 Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039 "PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule" XP_015430913.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015433519.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_015433004.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_015431119.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-7279 "Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)" XP_015435015.1 29 Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-167162 "RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape" XP_015438178.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015432711.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015434509.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_015433709.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_015434707.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015431931.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_015430965.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_015439907.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_015436190.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_015435432.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015430084.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_015439766.1 4 KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015433228.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_015435458.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015432951.1 33 Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-191859 "Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly" XP_015438495.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015435504.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174178 "Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_015435496.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_015431770.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015430624.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_015430131.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_015428659.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_015438261.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_015432603.1 22 KEGG: 00520+5.3.1.9;Reactome: R-HSA-6798695;MetaCyc: PWY-3801;MetaCyc: PWY-8013;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-621;MetaCyc: PWY-7238;Reactome: R-HSA-5628897;MetaCyc: PWY-7385;MetaCyc: PWY-6142;MetaCyc: PWY-6992;MetaCyc: PWY-622;MetaCyc: PWY-6981;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7347;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5384;MetaCyc: PWY-5659;MetaCyc: PWY-5514;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5054 "Amino sugar and nucleotide sugar metabolism";"Neutrophil degranulation";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis";"Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"Sucrose biosynthesis II";"TP53 Regulates Metabolic Genes";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,5-anhydrofructose degradation";"Starch biosynthesis";"Chitin biosynthesis";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis III";"Pentose phosphate pathway";"Sucrose degradation IV (sucrose phosphorylase)";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Starch and sucrose metabolism";"D-sorbitol biosynthesis I" XP_015431001.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_015438041.1 4 Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026 "Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_015434310.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_015432154.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015438616.1 6 KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204 "Inositol phosphate metabolism";"3-phosphoinositide degradation";"Rho GTPase cycle";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol" XP_015431921.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_015432770.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_015431487.1 44 Reactome: R-HSA-162658;Reactome: R-HSA-456926;Reactome: R-HSA-5654727;Reactome: R-HSA-5674135;Reactome: R-HSA-112409;Reactome: R-HSA-2559580;Reactome: R-HSA-6811558;Reactome: R-HSA-8939211;Reactome: R-HSA-6802948;Reactome: R-HSA-5675221;Reactome: R-HSA-5674499;Reactome: R-HSA-9627069;Reactome: R-HSA-5663213;Reactome: R-HSA-8943724;Reactome: R-HSA-5668599;Reactome: R-HSA-5654726;Reactome: R-HSA-3371453;Reactome: R-HSA-982772;Reactome: R-HSA-198753;Reactome: R-HSA-2559582;Reactome: R-HSA-5673001;Reactome: R-HSA-879415;Reactome: R-HSA-6802952;Reactome: R-HSA-445144;Reactome: R-HSA-2029482;Reactome: R-HSA-6802955;Reactome: R-HSA-1295596;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-8940973;Reactome: R-HSA-202670;Reactome: R-HSA-2559585;Reactome: R-HSA-9634638;Reactome: R-HSA-444257;Reactome: R-HSA-9635465;Reactome: R-HSA-881907;Reactome: R-HSA-170968;Reactome: R-HSA-375165;Reactome: R-HSA-74749;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;KEGG: 04150+2.7.11.24 "Golgi Cisternae Pericentriolar Stack Reorganization";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR2 signaling";"MAP2K and MAPK activation";"RAF-independent MAPK1/3 activation";"Oxidative Stress Induced Senescence";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ESR-mediated signaling";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Negative feedback regulation of MAPK pathway";"Regulation of the apoptosome activity";"RHO GTPases Activate WASPs and WAVEs";"Regulation of PTEN gene transcription";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR1 signaling";"Regulation of HSF1-mediated heat shock response";"Growth hormone receptor signaling";"ERK/MAPK targets";"Senescence-Associated Secretory Phenotype (SASP)";"RAF/MAP kinase cascade";"Advanced glycosylation endproduct receptor signaling";"Signaling by BRAF and RAF fusions";"Signal transduction by L1";"Regulation of actin dynamics for phagocytic cup formation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Spry regulation of FGF signaling";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"RUNX2 regulates osteoblast differentiation";"ERKs are inactivated";"Oncogene Induced Senescence";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RSK activation";"Suppression of apoptosis";"Gastrin-CREB signalling pathway via PKC and MAPK";"Frs2-mediated activation";"NCAM signaling for neurite out-growth";"Signal attenuation";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"mTOR signaling pathway" XP_015438290.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_015428875.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" XP_015433290.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015430977.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_015433487.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_015429572.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015435316.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_015432138.1 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_015435029.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_015439632.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-168276 "SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways" XP_015431141.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_015435137.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015430286.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015438503.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_015436011.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015437451.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015429785.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_015440347.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015428662.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_015431243.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-113507 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_015432954.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_015434051.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296 "CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome" XP_015428763.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_015434891.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015429349.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_015431386.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_015431164.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_015432017.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_015436132.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015435422.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015430366.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015438814.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_015432860.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_015435128.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_015429925.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300 "HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors" XP_015432936.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949664 "Mitochondrial protein import";"Processing of SMDT1" XP_015439142.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_015433762.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-428930 "G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor" XP_015433901.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_015437403.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015429636.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015435660.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_015432379.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_015432694.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_015435850.1 5 Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_015436801.1 3 MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451 "Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_015429129.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015428401.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_015439368.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_015428387.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015435327.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015435225.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_015430876.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015433893.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692 "Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity" XP_015430049.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_015439249.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_015430497.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_015433194.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015428565.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015432047.1 10 Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-5628897 "Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes" XP_015434755.1 10 Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-9627069 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity" XP_015433257.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_015439930.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174 "Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_015438186.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_015438861.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_015431259.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_015439950.1 34 Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9639288;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3108214 "HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amino acids regulate mTORC1";"tRNA processing in the nucleus";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins" XP_015429994.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_015433820.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015429081.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_015430480.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_015437443.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015438832.1 7 Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs" XP_015436001.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_015436983.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_015430371.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA" XP_015440374.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_015432160.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_015430620.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_015430034.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_015439828.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_015429097.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_015436125.1 7 KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897 "Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes" XP_015435253.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_015438622.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_015430098.1 15 Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398 "Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway" XP_015436779.1 3 KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347 "Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" XP_015430342.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_015436213.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015429887.1 7 Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_015433907.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_015436445.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1" XP_015439889.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015429082.1 8 Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-8953750 "Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6" XP_015431780.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015437733.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015433739.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_015428547.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015432982.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_015428731.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-380972 "Macroautophagy";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_015434930.1 5 KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4 "Geraniol degradation";"Butanoate metabolism";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies" XP_015430685.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_015429264.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_015439303.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN" XP_015436329.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015431992.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_015438711.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_015438862.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_015437984.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_015433440.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_015429343.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs" XP_015430702.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736 "Recycling pathway of L1";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors" XP_015434798.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome" XP_015437636.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_015431078.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_015436602.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_015433525.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_015428839.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" XP_015433356.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_015433619.1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_015434327.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015438843.1 20 Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-174411 "Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere" XP_015429038.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_015435338.1 7 KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204 "Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol" XP_015439441.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_015429109.1 1 MetaCyc: PWY-6938 "NADH repair" XP_015437671.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_015431677.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015434242.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_015430762.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_015431660.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_015438324.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_015439931.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015439475.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_015430484.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015435804.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_015430304.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015428439.1 6 Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;MetaCyc: PWY-5653 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_015440246.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015436541.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793 "RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis" XP_015429207.1 18 MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI" XP_015439385.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015432692.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187 "Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress" XP_015438977.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_015432531.1 5 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA" XP_015438695.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_015440344.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_015437807.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015430840.1 16 Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-75955 "TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation" XP_015432679.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_015438560.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_015435872.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015434270.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" XP_015437441.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_015438707.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_015432861.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_015439789.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001 "Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_015438681.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_015431547.1 11 Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_015431628.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_015431202.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_015438927.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_015431932.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_015435339.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_015438995.1 7 Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210 "Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling" XP_015435151.1 19 KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;Reactome: R-HSA-71403;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;KEGG: 00680+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-7115;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392 "Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methane metabolism";"Gluconeogenesis";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Pyruvate metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II" XP_015430892.1 4 KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Glycerophospholipid metabolism";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_015434212.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_015436631.1 3 MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315 "Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol" XP_015432129.1 11 Reactome: R-HSA-877312;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-512988;Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-389948;Reactome: R-HSA-432142 "Regulation of IFNG signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"PECAM1 interactions";"Interleukin-37 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"PD-1 signaling";"Platelet sensitization by LDL" XP_015435197.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015433473.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_015433070.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_015431399.1 11 MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-3861;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-6992;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916 "L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)" XP_015435388.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015429035.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015434622.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_015431210.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_015429095.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription" XP_015433527.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_015438650.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_015434206.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015437196.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_015434586.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination" XP_015436333.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_015429907.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015432495.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_015431585.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_015428484.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015434186.1 12 Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"Activation of AMPK downstream of NMDARs";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Macroautophagy" XP_015431342.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_015438858.1 12 Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Translation initiation complex formation";"ISG15 antiviral mechanism";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015432590.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015432984.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_015431530.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_015431322.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-73933;Reactome: R-HSA-110357 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1" XP_015437298.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_015435264.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_015433683.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015439737.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_015440141.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_015432019.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_015433030.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015433902.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015430402.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_015439076.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015433037.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_015435562.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_015440124.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_015433778.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_015428899.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_015429970.1 52 Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-1834949;Reactome: R-HSA-167246;Reactome: R-HSA-749476;Reactome: R-HSA-168325;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-8851708;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-6807505;Reactome: R-HSA-167238 "RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Abortive And Retractive Initiation";"Viral Messenger RNA Synthesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation" XP_015436722.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_015431343.1 8 Reactome: R-HSA-1855183;MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-4661 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_015435259.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015438692.1 26 Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190861 "Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Gap junction assembly" XP_015435346.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_015431720.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_015437503.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_015430740.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015429139.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_015439879.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_015440483.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-5619107 "SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_015437080.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_015428486.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_015435576.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_015438806.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6807505 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes" XP_015431706.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_015430292.1 3 MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway" XP_015440447.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_015437805.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_015436705.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_015438350.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_015437861.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_015435250.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_015434035.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_015428896.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_015431906.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_015438698.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_015436639.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_015440222.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015440058.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_015432582.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_015429083.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015435838.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015433909.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015436683.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_015432193.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_015429256.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_015436794.1 26 Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-380320 "COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Cilium Assembly";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes" XP_015434259.1 9 Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324 "Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_015432635.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015436651.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_015436743.1 182 Reactome: R-HSA-5684264;Reactome: R-HSA-5696394;Reactome: R-HSA-8875360;Reactome: R-HSA-180534;Reactome: R-HSA-5685942;Reactome: R-HSA-2559580;Reactome: R-HSA-9604323;Reactome: R-HSA-8863795;Reactome: R-HSA-1236382;Reactome: R-HSA-4641258;Reactome: R-HSA-2122948;Reactome: R-HSA-5607764;Reactome: R-HSA-6807004;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-110312;Reactome: R-HSA-8939236;Reactome: R-HSA-3134975;Reactome: R-HSA-162588;Reactome: R-HSA-6781823;Reactome: R-HSA-2894862;Reactome: R-HSA-175474;Reactome: R-HSA-2122947;Reactome: R-HSA-182971;Reactome: R-HSA-5693565;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-2559585;Reactome: R-HSA-174490;Reactome: R-HSA-2173796;Reactome: R-HSA-9615710;Reactome: R-HSA-975163;Reactome: R-HSA-5654733;Reactome: R-HSA-8866654;Reactome: R-HSA-5656121;Reactome: R-HSA-5689901;Reactome: R-HSA-174084;Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-6782135;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-8852276;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-975110;Reactome: R-HSA-9645460;Reactome: R-HSA-174048;Reactome: R-HSA-156827;Reactome: R-HSA-174178;Reactome: R-HSA-445989;Reactome: R-HSA-68949;Reactome: R-HSA-201681;Reactome: R-HSA-8856828;Reactome: R-HSA-5689877;Reactome: R-HSA-532668;Reactome: R-HSA-179409;Reactome: R-HSA-68827;Reactome: R-HSA-8948747;Reactome: R-HSA-2559582;Reactome: R-HSA-174113;Reactome: R-HSA-6804760;Reactome: R-HSA-5610780;Reactome: R-HSA-9633012;Reactome: R-HSA-9013507;Reactome: R-HSA-450321;Reactome: R-HSA-69601;Reactome: R-HSA-69541;Reactome: R-HSA-8856825;Reactome: R-HSA-2672351;Reactome: R-HSA-72706;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-400253;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-5654732;Reactome: R-HSA-9636383;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-72689;Reactome: R-HSA-8849469;Reactome: R-HSA-2467813;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-195253;Reactome: R-HSA-8866652;Reactome: R-HSA-69481;Reactome: R-HSA-5693607;Reactome: R-HSA-3769402;Reactome: R-HSA-2173791;Reactome: R-HSA-2644606;Reactome: R-HSA-937039;Reactome: R-HSA-975144;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-168928;Reactome: R-HSA-975957;Reactome: R-HSA-5675221;Reactome: R-HSA-936964;Reactome: R-HSA-5655862;Reactome: R-HSA-937041;Reactome: R-HSA-6804757;Reactome: R-HSA-9613829;Reactome: R-HSA-1799339;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-4641263;Reactome: R-HSA-6782210;Reactome: R-HSA-2565942;Reactome: R-HSA-3322077;Reactome: R-HSA-192823;Reactome: R-HSA-5610783;Reactome: R-HSA-2979096;Reactome: R-HSA-937042;Reactome: R-HSA-180585;Reactome: R-HSA-917937;Reactome: R-HSA-5696395;Reactome: R-HSA-209543;Reactome: R-HSA-6804756;Reactome: R-HSA-1295596;Reactome: R-HSA-5668541;Reactome: R-HSA-72695;Reactome: R-HSA-2173795;Reactome: R-HSA-5362768;Reactome: R-HSA-5357956;Reactome: R-HSA-5358346;Reactome: R-HSA-6791226;Reactome: R-HSA-6783310;Reactome: R-HSA-174184;Reactome: R-HSA-3785653;Reactome: R-HSA-187577;Reactome: R-HSA-9637628;Reactome: R-HSA-69231;Reactome: R-HSA-1236974;Reactome: R-HSA-168638;Reactome: R-HSA-5675482;Reactome: R-HSA-9013973;Reactome: R-HSA-2691232;Reactome: R-HSA-5654727;Reactome: R-HSA-2173788;Reactome: R-HSA-936440;Reactome: R-HSA-5696397;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-1169408;Reactome: R-HSA-5607761;Reactome: R-HSA-8876493;Reactome: R-HSA-9646399;Reactome: R-HSA-4608870;Reactome: R-HSA-450302;Reactome: R-HSA-349425;Reactome: R-HSA-5654726;Reactome: R-HSA-901032;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5689896;Reactome: R-HSA-9010553;Reactome: R-HSA-6781827;Reactome: R-HSA-9033241;Reactome: R-HSA-168927;Reactome: R-HSA-5205685;Reactome: R-HSA-8854050;Reactome: R-HSA-977225;Reactome: R-HSA-912631;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-975956;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-382556;Reactome: R-HSA-917729;Reactome: R-HSA-1358803;Reactome: R-HSA-9014325;Reactome: R-HSA-2408557;Reactome: R-HSA-5357905 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"DNA Damage Recognition in GG-NER";"InlB-mediated entry of Listeria monocytogenes into host cell";"Vpu mediated degradation of CD4";"HDR through Homologous Recombination (HRR)";"Oxidative Stress Induced Senescence";"Negative regulation of NOTCH4 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Degradation of DVL";"Activated NOTCH1 Transmits Signal to the Nucleus";"CLEC7A (Dectin-1) signaling";"Negative regulation of MET activity";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Translesion synthesis by REV1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of innate immune responses to cytosolic DNA";"Budding and maturation of HIV virion";"Formation of TC-NER Pre-Incision Complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Assembly Of The HIV Virion";"NOTCH1 Intracellular Domain Regulates Transcription";"EGFR downregulation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Oncogene Induced Senescence";"Membrane binding and targetting of GAG proteins";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Late endosomal microautophagy";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Negative regulation of FGFR4 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by POLI";"Metalloprotease DUBs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"Dual incision in TC-NER";"Peptide chain elongation";"Translation initiation complex formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Alpha-protein kinase 1 signaling pathway";"APC/C:Cdc20 mediated degradation of Cyclin B";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Orc1 removal from chromatin";"TCF dependent signaling in response to WNT";"Clathrin-mediated endocytosis";"Josephin domain DUBs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"APC-Cdc20 mediated degradation of Nek2A";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN localization";"Senescence-Associated Secretory Phenotype (SASP)";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of TP53 Activity through Methylation";"Degradation of GLI1 by the proteasome";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Stabilization of p53";"Cargo recognition for clathrin-mediated endocytosis";"Stimuli-sensing channels";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Circadian Clock";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"Negative regulation of FGFR3 signaling";"Prevention of phagosomal-lysosomal fusion";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Formation of a pool of free 40S subunits";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Separation of Sister Chromatids";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Degradation of beta-catenin by the destruction complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"G2/M Checkpoints";"Processing of DNA double-strand break ends";"Deactivation of the beta-catenin transactivating complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Negative regulation of MAPK pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Translesion synthesis by POLK";"IKK complex recruitment mediated by RIP1";"Regulation of TP53 Degradation";"Chaperone Mediated Autophagy";"SRP-dependent cotranslational protein targeting to membrane";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Regulation of FZD by ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PLK1 Activity at G2/M Transition";"Glycogen synthesis";"Viral mRNA Translation";"Degradation of GLI2 by the proteasome";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"Vif-mediated degradation of APOBEC3G";"Iron uptake and transport";"Formation of Incision Complex in GG-NER";"p75NTR recruits signalling complexes";"Regulation of TP53 Activity through Phosphorylation";"Spry regulation of FGF signaling";"TNFR2 non-canonical NF-kB pathway";"Formation of the ternary complex, and subsequently, the 43S complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR1-induced NFkappaB signaling pathway";"Hedgehog ligand biogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Fanconi Anemia Pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Myoclonic epilepsy of Lafora";"SCF(Skp2)-mediated degradation of p27/p21";"Modulation by Mtb of host immune system";"Cyclin D associated events in G1";"ER-Phagosome pathway";"NOD1/2 Signaling Pathway";"Regulation of necroptotic cell death";"TICAM1-dependent activation of IRF3/IRF7";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Negative regulation of FGFR2 signaling";"Downregulation of TGF-beta receptor signaling";"Negative regulators of DDX58/IFIH1 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Neddylation";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"ISG15 antiviral mechanism";"Dectin-1 mediated noncanonical NF-kB signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Aggrephagy";"Asymmetric localization of PCP proteins";"activated TAK1 mediates p38 MAPK activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of FGFR1 signaling";"ER Quality Control Compartment (ERQC)";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Ovarian tumor domain proteases";"Regulation of expression of SLITs and ROBOs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Peroxisomal protein import";"TICAM1, RIP1-mediated IKK complex recruitment";"Pink/Parkin Mediated Mitophagy";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Amyloid fiber formation";"Regulation of signaling by CBL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"ABC-family proteins mediated transport";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Downregulation of ERBB2:ERBB3 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Selenocysteine synthesis";"Regulation of TNFR1 signaling" XP_015429364.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14 "Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism" XP_015430033.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_015435884.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_015434093.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_015428780.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_015430963.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_015436569.1 14 MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7783 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen degradation" XP_015438360.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_015439966.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015431216.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_015434061.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_015435436.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_015434159.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_015431029.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_015433988.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_015438826.1 7 Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid" XP_015438778.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_015440457.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_015436535.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN" XP_015436771.1 3 KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3 "Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism" XP_015436465.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_015433234.1 9 Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-7411 "Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)" XP_015429452.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_015435895.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015431772.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_015434372.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_015440371.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_015435963.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_015438965.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_015439799.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_015433096.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_015429419.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_015428767.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_015430691.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_015428826.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_015431752.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_015439196.1 12 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73772 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape" XP_015435126.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_015430750.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_015437747.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_015432355.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_015433585.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_015433900.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_015433156.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015429240.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_015430875.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_015439294.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_015431730.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_015431085.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_015435424.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_015429689.1 4 KEGG: 00513+3.2.1.113;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.113;Reactome: R-HSA-901032 "Various types of N-glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"ER Quality Control Compartment (ERQC)" XP_015431389.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_015436303.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_015433828.1 5 KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3 "Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine catabolism";"Drug metabolism - other enzymes" XP_015431439.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_015433960.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_015429420.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_015430859.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_015439152.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_015439771.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_015428418.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_015429313.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_015429115.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_015439246.1 7 MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124 "Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II" XP_015431358.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_015437125.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_015429110.1 1 MetaCyc: PWY-6938 "NADH repair" XP_015432458.1 7 Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;Reactome: R-HSA-1660514 "Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane" XP_015429656.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_015431543.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "G0 and Early G1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex"