Accession_ID Pathway_Count Pathway_IDs Pathway_Names EDAN000389-PA 5 MetaCyc: PWY-7674;MetaCyc: PWY-1269;MetaCyc: PWY-6164;KEGG: 00540+2.5.1.55;KEGG: 00400+2.5.1.54 "CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"3-dehydroquinate biosynthesis I";"Lipopolysaccharide biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN011451-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN001122-PA 3 Reactome: R-HSA-4086400;Reactome: R-HSA-4608870;Reactome: R-HSA-373080 "PCP/CE pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)" EDAN007774-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN016235-PA 6 Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;Reactome: R-HSA-975634 "The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"Retinoid metabolism and transport" EDAN010539-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN007626-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN016686-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN003249-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN009285-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN006788-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN000595-PA 6 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" EDAN011990-PA 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" EDAN000705-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN000623-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN001619-PA 5 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" EDAN001490-PA 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" EDAN007301-PA 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" EDAN007040-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" EDAN018044-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN003418-PA 3 MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" EDAN005318-PA 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" EDAN008977-PA 5 Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" EDAN002263-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN015309-PA 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" EDAN006155-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" EDAN018705-PA 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN011280-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" EDAN014090-PA 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" EDAN018065-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN012077-PA 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" EDAN018933-PA 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" EDAN002940-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" EDAN002636-PA 12 Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-73762;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription" EDAN000313-PA 9 MetaCyc: PWY-7442;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-6983;MetaCyc: PWY-5664 "Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" EDAN003448-PA 2 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Glycine, serine and threonine metabolism";"Methane metabolism" EDAN013180-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" EDAN018832-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN001230-PA 7 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-2894862;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796 "PPARA activates gene expression";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" EDAN004993-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN010167-PA 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" EDAN011447-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" EDAN004442-PA 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" EDAN019477-PA 13 MetaCyc: PWY-6549;MetaCyc: PWY-7124;KEGG: 00720+4.1.1.31;MetaCyc: PWY-6142;KEGG: 00680+4.1.1.31;KEGG: 00620+4.1.1.31;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00710+4.1.1.31;MetaCyc: PWY-6146;MetaCyc: PWY-1622;MetaCyc: PWY-7115;MetaCyc: PWY-5913 "L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Carbon fixation in photosynthetic organisms";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)" EDAN009264-PA 9 Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-1362277;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-176187 "CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress" EDAN011902-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN004063-PA 5 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" EDAN009248-PA 1 Reactome: R-HSA-1483166 "Synthesis of PA" EDAN009638-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN000591-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN010342-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN000282-PA 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" EDAN003174-PA 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" EDAN014489-PA 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" EDAN012452-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN018360-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" EDAN002994-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" EDAN018848-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN007082-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN003889-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" EDAN019236-PA 2 Reactome: R-HSA-2453902;Reactome: R-HSA-2187335 "The canonical retinoid cycle in rods (twilight vision)";"The retinoid cycle in cones (daylight vision)" EDAN019158-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN019219-PA 14 MetaCyc: PWY-4302;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-561;Reactome: R-HSA-71403;Reactome: R-HSA-611105;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254 "Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)" EDAN017704-PA 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" EDAN001150-PA 2 MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" EDAN007332-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN015126-PA 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" EDAN008582-PA 7 Reactome: R-HSA-389661;KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12 "Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)" EDAN006948-PA 11 Reactome: R-HSA-164378;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615 "PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation" EDAN010341-PA 3 MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451 "Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" EDAN000762-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN019126-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" EDAN001813-PA 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" EDAN002220-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" EDAN001978-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN019173-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN005724-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" EDAN005731-PA 17 KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-7115;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37 "Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"Methane metabolism" EDAN000165-PA 7 KEGG: 00670+2.1.2.9;KEGG: 00670+3.5.1.10;KEGG: 00630+3.5.1.10;KEGG: 00970+2.1.2.9;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-5497 "One carbon pool by folate";"One carbon pool by folate";"Glyoxylate and dicarboxylate metabolism";"Aminoacyl-tRNA biosynthesis";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)" EDAN010360-PA 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" EDAN015678-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN013865-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" EDAN007842-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN008479-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN008096-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" EDAN012892-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" EDAN002977-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis" EDAN006690-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN000601-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-5419276;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Mitochondrial translation termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" EDAN014458-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN005710-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN001204-PA 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921 "Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" EDAN001694-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" EDAN002685-PA 10 KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"Other glycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"HS-GAG degradation" EDAN014408-PA 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" EDAN014254-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN000365-PA 3 MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)" EDAN009908-PA 57 Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154 "FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin" EDAN014613-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN015111-PA 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" EDAN016364-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" EDAN000070-PA 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7 "Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism" EDAN010324-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN016932-PA 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" EDAN000814-PA 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" EDAN006858-PA 7 Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" EDAN009116-PA 57 Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017 "FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6" EDAN016275-PA 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" EDAN017584-PA 7 MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7185;MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"Purine metabolism" EDAN007915-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN008227-PA 8 Reactome: R-HSA-1989781;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-6174 "PPARA activates gene expression";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)" EDAN002547-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN007239-PA 33 Reactome: R-HSA-69656;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" EDAN015397-PA 4 Reactome: R-HSA-189483;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;MetaCyc: PWY-5874 "Heme degradation";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation I" EDAN014406-PA 3 Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105 "Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation" EDAN018518-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN011571-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN011295-PA 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" EDAN003346-PA 2 MetaCyc: PWY-6700;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" EDAN012980-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN015831-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN002194-PA 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" EDAN005018-PA 5 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism" EDAN010115-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN005515-PA 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" EDAN017960-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN009596-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN007088-PA 4 Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211 "Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes" EDAN003717-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN002968-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN008502-PA 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" EDAN015431-PA 1 Reactome: R-HSA-186797 "Signaling by PDGF" EDAN004261-PA 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" EDAN016534-PA 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis" EDAN007059-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN000417-PA 14 Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7279;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302 "Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)" EDAN007909-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN008592-PA 1 Reactome: R-HSA-1221632 "Meiotic synapsis" EDAN019287-PA 5 Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-3247509 "Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes" EDAN011140-PA 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" EDAN007902-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" EDAN016584-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN018229-PA 17 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" EDAN009687-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN012503-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" EDAN005735-PA 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" EDAN019159-PA 2 MetaCyc: PWY-6654;KEGG: 00770+2.1.2.11 "Phosphopantothenate biosynthesis III (archaebacteria)";"Pantothenate and CoA biosynthesis" EDAN019271-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN000552-PA 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" EDAN005470-PA 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" EDAN000168-PA 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" EDAN008761-PA 10 KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Neutrophil degranulation";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Galactose metabolism" EDAN010311-PA 1 Reactome: R-HSA-373753 "Nephrin family interactions" EDAN005077-PA 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" EDAN000756-PA 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN015127-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN005538-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" EDAN016737-PA 1 Reactome: R-HSA-916853 "Degradation of GABA" EDAN014525-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN016314-PA 9 Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827 "Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" EDAN008911-PA 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" EDAN008160-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN014853-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" EDAN014422-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" EDAN016517-PA 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" EDAN012067-PA 13 KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5 "Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism" EDAN005705-PA 7 MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-6596 "Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Adenosine nucleotides degradation I" EDAN015656-PA 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" EDAN018365-PA 3 MetaCyc: PWY-5265;MetaCyc: PWY-6471;KEGG: 00550+3.4.16.4 "Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis" EDAN002235-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" EDAN017204-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN006249-PA 11 Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Dual Incision in GG-NER";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" EDAN005905-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" EDAN013335-PA 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" EDAN000158-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" EDAN005658-PA 11 MetaCyc: PWY-5971;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-7858;KEGG: 00061+1.3.1.9;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5973 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Cis-vaccenate biosynthesis" EDAN002441-PA 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" EDAN003146-PA 42 Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-9616222;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-171306;Reactome: R-HSA-5578749;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-3214841;Reactome: R-HSA-9610379;Reactome: R-HSA-3214842;Reactome: R-HSA-427389;Reactome: R-HSA-110330;Reactome: R-HSA-2299718;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-912446 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Opening";"DNA methylation";"Amyloid fiber formation";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"HATs acetylate histones";"HDACs deacetylate histones";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RMTs methylate histone arginines";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Packaging Of Telomere Ends";"Transcriptional regulation by small RNAs";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"PKMTs methylate histone lysines";"HCMV Late Events";"HDMs demethylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Condensation of Prophase Chromosomes";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination" EDAN001304-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN000144-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN015601-PA 24 Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-9010642;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163560;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-163358;Reactome: R-HSA-8853659;Reactome: R-HSA-111931;Reactome: R-HSA-9634600;Reactome: R-HSA-8963896;Reactome: R-HSA-983231;Reactome: R-HSA-422356;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-164378;Reactome: R-HSA-392517 "Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"ROBO receptors bind AKAP5";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"mTOR signaling pathway";"Triglyceride catabolism";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"PKA-mediated phosphorylation of key metabolic factors";"RET signaling";"PKA-mediated phosphorylation of CREB";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"HDL assembly";"Factors involved in megakaryocyte development and platelet production";"Regulation of insulin secretion";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"PKA activation in glucagon signalling";"Rap1 signalling" EDAN002759-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN017222-PA 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" EDAN003374-PA 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" EDAN010229-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN011805-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" EDAN010452-PA 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" EDAN009576-PA 16 Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-9020702;Reactome: R-HSA-975155;Reactome: R-HSA-5602680;Reactome: R-HSA-1236974;Reactome: R-HSA-209543;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-5602498;Reactome: R-HSA-975138;Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-1810476;Reactome: R-HSA-166058;Reactome: R-HSA-975871 "PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-1 signaling";"MyD88 dependent cascade initiated on endosome";"MyD88 deficiency (TLR5)";"ER-Phagosome pathway";"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 deficiency (TLR2/4)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"RIP-mediated NFkB activation via ZBP1";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane" EDAN001549-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN009439-PA 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" EDAN013538-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN004503-PA 6 Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes" EDAN008285-PA 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402 "RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex" EDAN011229-PA 7 MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" EDAN008173-PA 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" EDAN005186-PA 5 Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68867 "CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex" EDAN013779-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" EDAN007964-PA 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape" EDAN005549-PA 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" EDAN000688-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN010269-PA 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" EDAN015194-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN015072-PA 9 Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476 "Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"G alpha (q) signalling events" EDAN008097-PA 14 Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416 "Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" EDAN006742-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" EDAN014225-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" EDAN000503-PA 2 MetaCyc: PWY-7380;KEGG: 00780+6.3.3.3 "Biotin biosynthesis from 8-amino-7-oxononanoate II";"Biotin metabolism" EDAN004748-PA 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" EDAN003237-PA 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN019376-PA 17 Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-1169091;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-4086398;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-202424;Reactome: R-HSA-937072 "FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"Downstream TCR signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" EDAN010370-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-3238698 "Neutrophil degranulation";"WNT ligand biogenesis and trafficking" EDAN009742-PA 13 KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00230+3.6.1.66;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7184;Reactome: R-HSA-74259;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545 "Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine catabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN019427-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN019304-PA 3 KEGG: 00540+2.3.1.129;MetaCyc: PWY-8073;Reactome: R-HSA-446205 "Lipopolysaccharide biosynthesis";"Lipid IVA biosynthesis (P. putida)";"Synthesis of GDP-mannose" EDAN001908-PA 16 Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-3214847;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565 "Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HATs acetylate histones";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" EDAN013536-PA 8 Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68962 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"DNA replication initiation";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex" EDAN014649-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN012065-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" EDAN006807-PA 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" EDAN018454-PA 27 Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-1169408 "Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism" EDAN003217-PA 7 MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2 "Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism" EDAN007823-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" EDAN003779-PA 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" EDAN002749-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN002791-PA 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" EDAN007090-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN014167-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN000003-PA 2 KEGG: 00430+1.4.1.1;KEGG: 00250+1.4.1.1 "Taurine and hypotaurine metabolism";"Alanine, aspartate and glutamate metabolism" EDAN003053-PA 5 KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)" EDAN011763-PA 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" EDAN002764-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN013887-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN008319-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN002986-PA 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis" EDAN016665-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN010902-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN001475-PA 15 Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-113418 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex" EDAN018408-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" EDAN000193-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" EDAN003154-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN000667-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN003355-PA 13 MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-7003;KEGG: 00260+5.4.2.12;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00010+5.4.2.12;KEGG: 00680+5.4.2.12;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7124 "Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Ethylene biosynthesis V (engineered)" EDAN018812-PA 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" EDAN002114-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" EDAN005730-PA 5 KEGG: 00360+1.11.1.21;KEGG: 00940+1.11.1.21;KEGG: 00380+1.11.1.21;MetaCyc: PWY-5506;KEGG: 00983+1.11.1.21 "Phenylalanine metabolism";"Phenylpropanoid biosynthesis";"Tryptophan metabolism";"Methanol oxidation to formaldehyde IV";"Drug metabolism - other enzymes" EDAN006764-PA 42 KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-6435;KEGG: 00627+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7654;MetaCyc: PWY-6583;MetaCyc: PWY-6945;MetaCyc: PWY-6863;MetaCyc: PWY-7778;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7216;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-5136;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7606;MetaCyc: PWY-6944;KEGG: 00623+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-6946;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7094;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35 "Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Aminobenzoate degradation";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Pyruvate fermentation to hexanol (engineered)";"2-methylpropene degradation";"Limonene and pinene degradation";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Geraniol degradation";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation II (plant peroxisome)";"Butanoate metabolism";"Tryptophan metabolism";"Spodoptera littoralis pheromone biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Androstenedione degradation";"Toluene degradation";"Butanoate metabolism";"Benzoate degradation";"Caprolactam degradation";"beta-Alanine metabolism";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid salvage";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation" EDAN005085-PA 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism" EDAN000513-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" EDAN002949-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" EDAN000393-PA 3 MetaCyc: PWY-5514;KEGG: 00520+2.3.1.157+2.7.7.23;Reactome: R-HSA-446205 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose" EDAN018088-PA 9 KEGG: 00340+4.2.1.19;KEGG: 00401+2.6.1.9;KEGG: 00350+2.6.1.9;KEGG: 00340+1.1.1.23;KEGG: 00340+2.6.1.9;KEGG: 00960+2.6.1.9;KEGG: 00400+2.6.1.9;KEGG: 00360+2.6.1.9;KEGG: 00340+5.3.1.16 "Histidine metabolism";"Novobiocin biosynthesis";"Tyrosine metabolism";"Histidine metabolism";"Histidine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Histidine metabolism" EDAN000545-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" EDAN003543-PA 8 Reactome: R-HSA-73614;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-6556;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5 "Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" EDAN009251-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN004455-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN011414-PA 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress" EDAN003421-PA 7 Reactome: R-HSA-163210;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201 "Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Oxidative phosphorylation";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis" EDAN007623-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN018612-PA 11 KEGG: 00730+2.5.1.3;MetaCyc: PWY-7356;MetaCyc: PWY-6907;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00730+2.8.1.10;MetaCyc: PWY-7357;MetaCyc: PWY-6897;MetaCyc: PWY-6893;MetaCyc: PWY-6908;MetaCyc: PWY-6894 "Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Thiamine formation from pyrithiamine and oxythiamine (yeast)";"Thiamine salvage II";"Thiamine diphosphate biosynthesis II (Bacillus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis I (E. coli)" EDAN011277-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN008998-PA 1 Reactome: R-HSA-3000178 "ECM proteoglycans" EDAN018321-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN006424-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN016757-PA 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Ligand-receptor interactions" EDAN003474-PA 2 Reactome: R-HSA-139853;Reactome: R-HSA-418346 "Elevation of cytosolic Ca2+ levels";"Platelet homeostasis" EDAN015585-PA 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" EDAN004935-PA 3 Reactome: R-HSA-114608;Reactome: R-HSA-195399;Reactome: R-HSA-194313 "Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization";"VEGF ligand-receptor interactions" EDAN012984-PA 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" EDAN007681-PA 4 KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801 "Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion" EDAN011657-PA 1 KEGG: 00190+2.7.4.1 "Oxidative phosphorylation" EDAN013328-PA 13 MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis" EDAN010860-PA 17 Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-5651801;Reactome: R-HSA-110314 "Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex" EDAN008263-PA 18 Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" EDAN012767-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN000425-PA 12 MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5132;MetaCyc: PWY-5133;MetaCyc: PWY-7857 "L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methane metabolism";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis" EDAN010609-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN016751-PA 10 MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3 "Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms" EDAN000602-PA 16 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" EDAN015174-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" EDAN010128-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN019299-PA 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" EDAN012618-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN005387-PA 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN010421-PA 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" EDAN002905-PA 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress" EDAN003273-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN003490-PA 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" EDAN000150-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN014848-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" EDAN003516-PA 5 Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471 "VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Downstream signal transduction";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" EDAN000235-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" EDAN010676-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN018695-PA 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" EDAN016865-PA 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" EDAN002493-PA 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)" EDAN007757-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN003996-PA 5 Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233 "Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway" EDAN001292-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN000407-PA 2 MetaCyc: PWY-7183;KEGG: 00240+2.4.2.9 "Pyrimidine nucleobases salvage I";"Pyrimidine metabolism" EDAN011701-PA 3 Reactome: R-HSA-204174;Reactome: R-HSA-70895;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid" EDAN018745-PA 14 Reactome: R-HSA-70895;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;Reactome: R-HSA-5362517;MetaCyc: PWY-6964;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;Reactome: R-HSA-204174;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2 "Branched-chain amino acid catabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Signaling by Retinoic Acid";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism" EDAN004530-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN000035-PA 2 MetaCyc: PWY-8106;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" EDAN008417-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN010418-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN002288-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" EDAN008509-PA 11 Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8 "Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Fructose and mannose metabolism" EDAN019314-PA 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" EDAN002788-PA 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" EDAN006228-PA 2 KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250 "Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis" EDAN000129-PA 8 KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-6791462;Reactome: R-HSA-163754;Reactome: R-HSA-6791055 "Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P" EDAN001386-PA 7 MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201 "ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Cristae formation";"Oxidative phosphorylation";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis" EDAN003497-PA 2 KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation" EDAN007500-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" EDAN002822-PA 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" EDAN002350-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN013387-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006488-PA 10 MetaCyc: PWY-7328;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose catabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)" EDAN017434-PA 18 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" EDAN003515-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN019464-PA 20 MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7337 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)" EDAN003375-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN006784-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" EDAN008657-PA 6 Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-5620922 "Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium" EDAN012925-PA 3 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" EDAN004168-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN012421-PA 6 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" EDAN004314-PA 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" EDAN016212-PA 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" EDAN001896-PA 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" EDAN001248-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN000448-PA 2 MetaCyc: PWY-6163;KEGG: 00400+4.2.3.5 "Chorismate biosynthesis from 3-dehydroquinate";"Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN016447-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" EDAN018471-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" EDAN007480-PA 5 MetaCyc: PWY-6823;Reactome: R-HSA-3214847;MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12 "Molybdenum cofactor biosynthesis";"HATs acetylate histones";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" EDAN012317-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" EDAN000462-PA 6 Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-389661;Reactome: R-HSA-199220;Reactome: R-HSA-75105 "Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Glyoxylate metabolism and glycine degradation";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis" EDAN008499-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" EDAN015524-PA 3 KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403 "Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling" EDAN000246-PA 9 Reactome: R-HSA-70921;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.5;MetaCyc: PWY-5030;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5497;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;KEGG: 00340+2.1.2.5 "Histidine catabolism";"Mitochondrial translation initiation";"One carbon pool by folate";"L-histidine degradation III";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Histidine metabolism" EDAN010911-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN000230-PA 4 Reactome: R-HSA-1296072;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70895 "Voltage gated Potassium channels";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism" EDAN005022-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN011046-PA 5 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" EDAN001468-PA 11 Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-72163;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"mRNA Splicing - Major Pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription" EDAN005752-PA 4 MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN012825-PA 4 Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555 "Downstream signal transduction";"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1" EDAN007805-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN007386-PA 13 MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis" EDAN010264-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN007066-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN007860-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" EDAN019033-PA 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" EDAN008421-PA 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1" EDAN003549-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" EDAN000096-PA 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" EDAN005499-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" EDAN018177-PA 3 KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043 "Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis" EDAN011437-PA 7 MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205 "Adenosine nucleotides degradation I";"Neutrophil degranulation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes" EDAN006573-PA 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" EDAN011779-PA 56 Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408 "Regulation of RAS by GAPs";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Hedgehog 'on' state";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA" EDAN003285-PA 17 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-5368286;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-5419276;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1236974;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-5389840;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Mitochondrial translation initiation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Mitochondrial translation termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"ER-Phagosome pathway";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Mitochondrial translation elongation";"SRP-dependent cotranslational protein targeting to membrane" EDAN004594-PA 14 MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" EDAN013489-PA 4 Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)" EDAN005732-PA 14 Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690 "Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)" EDAN015538-PA 14 MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51 "Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism" EDAN000310-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN019228-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" EDAN016626-PA 8 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes" EDAN015189-PA 19 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"VLDL assembly";"Chylomicron remodeling";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Chylomicron assembly";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"LDL remodeling";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors" EDAN003437-PA 7 Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN012402-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" EDAN012417-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN016077-PA 13 KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822 "Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Other glycan degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)" EDAN007118-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN012073-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN012246-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" EDAN010024-PA 29 Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" EDAN002274-PA 6 Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;MetaCyc: PWY-7391 "Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)" EDAN011575-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN011356-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN003173-PA 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" EDAN003286-PA 17 Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" EDAN001001-PA 6 Reactome: R-HSA-70370;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12 "Galactose catabolism";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism" EDAN018764-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN013855-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN007908-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN001635-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN008695-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" EDAN011041-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN009860-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN000107-PA 4 MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255 "Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis" EDAN002826-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" EDAN013727-PA 1 Reactome: R-HSA-400253 "Circadian Clock" EDAN006382-PA 7 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" EDAN012493-PA 5 MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6121 "5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I" EDAN000943-PA 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" EDAN017909-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis" EDAN005123-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN015238-PA 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" EDAN002204-PA 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" EDAN016832-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN018186-PA 1 Reactome: R-HSA-70350 "Fructose catabolism" EDAN007931-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" EDAN004229-PA 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" EDAN008408-PA 2 Reactome: R-HSA-210746;Reactome: R-HSA-210745 "Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells" EDAN018883-PA 3 KEGG: 00250+1.4.1.1;KEGG: 00430+1.4.1.1;Reactome: R-HSA-71403 "Alanine, aspartate and glutamate metabolism";"Taurine and hypotaurine metabolism";"Citric acid cycle (TCA cycle)" EDAN003047-PA 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" EDAN004429-PA 40 Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-112382 "Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex" EDAN002929-PA 18 MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-7383;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37 "Reductive TCA cycle II";"Methylaspartate cycle";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism" EDAN010404-PA 9 MetaCyc: PWY-6471;MetaCyc: PWY-6470;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;KEGG: 00510+2.4.1.141;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6385;Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" EDAN015008-PA 9 MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476 "D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events" EDAN006342-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN017547-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN010586-PA 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" EDAN019508-PA 3 KEGG: 00220+1.2.1.38;MetaCyc: PWY-5154;MetaCyc: PWY-7400 "Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)" EDAN009843-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN011976-PA 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" EDAN002051-PA 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" EDAN005676-PA 2 Reactome: R-HSA-446205;KEGG: 00300+2.3.1.117 "Synthesis of GDP-mannose";"Lysine biosynthesis" EDAN019556-PA 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" EDAN018732-PA 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism" EDAN005791-PA 4 MetaCyc: PWY-6519;MetaCyc: PWY-6578;KEGG: 00780+2.3.1.47;MetaCyc: PWY-7147 "8-amino-7-oxononanoate biosynthesis I";"8-amino-7-oxononanoate biosynthesis III";"Biotin metabolism";"8-amino-7-oxononanoate biosynthesis II" EDAN000757-PA 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" EDAN004054-PA 4 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" EDAN012411-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" EDAN016175-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" EDAN013025-PA 18 Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167158 "RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex" EDAN014324-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" EDAN018507-PA 15 Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange" EDAN017305-PA 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" EDAN014817-PA 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" EDAN010524-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" EDAN000994-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" EDAN015032-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN007594-PA 3 Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101 "MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation" EDAN018235-PA 16 Reactome: R-HSA-5389840;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-5419276;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-5368286;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "Mitochondrial translation elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Mitochondrial translation termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Mitochondrial translation initiation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation" EDAN014397-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" EDAN004120-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN004525-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" EDAN015470-PA 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" EDAN003256-PA 5 MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" EDAN010114-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" EDAN008343-PA 27 Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379 "Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"HCMV Late Events" EDAN005049-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" EDAN019107-PA 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" EDAN005759-PA 7 MetaCyc: PWY-5316;MetaCyc: PWY-5653;MetaCyc: PWY-7342;MetaCyc: PWY-5381;KEGG: 00760+2.4.2.19;KEGG: 00760+6.3.4.21;Reactome: R-HSA-196807 "Nicotine biosynthesis";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Superpathway of nicotine biosynthesis";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" EDAN005647-PA 4 KEGG: 00400+2.5.1.19;MetaCyc: PWY-6163;KEGG: 00240+2.7.4.25;MetaCyc: PWY-7205 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Chorismate biosynthesis from 3-dehydroquinate";"Pyrimidine metabolism";"CMP phosphorylation" EDAN007142-PA 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" EDAN000080-PA 10 MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-7124 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)" EDAN000170-PA 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" EDAN000317-PA 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" EDAN006418-PA 8 Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-164378 "Factors involved in megakaryocyte development and platelet production";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling" EDAN012718-PA 14 MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-181 "Folate polyglutamylation";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Folate transformations II (plants)";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines";"Methane metabolism";"Folate transformations I";"Photorespiration " EDAN005498-PA 1 Reactome: R-HSA-373753 "Nephrin family interactions" EDAN011311-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway" EDAN015809-PA 5 Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906 "Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation" EDAN011843-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN011399-PA 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" EDAN011239-PA 9 Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-241 "Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" EDAN004795-PA 8 KEGG: 00240+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-6556;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine salvage" EDAN016330-PA 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" EDAN012508-PA 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" EDAN006355-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis" EDAN003179-PA 1 KEGG: 00400+4.1.1.48 "Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN000321-PA 5 MetaCyc: PWY-8010;KEGG: 00260+1.1.1.95;KEGG: 00270+1.1.1.95;KEGG: 00680+1.1.1.95;Reactome: R-HSA-977347 "L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Methane metabolism";"Serine biosynthesis" EDAN017835-PA 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN016791-PA 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" EDAN009337-PA 7 Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry" EDAN005747-PA 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism" EDAN004435-PA 3 MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57 "Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism" EDAN016777-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN005520-PA 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" EDAN005379-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN013643-PA 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" EDAN001820-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" EDAN003172-PA 3 MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" EDAN013288-PA 7 MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;Reactome: R-HSA-1660499 "3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"Synthesis of PIPs at the plasma membrane" EDAN002951-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN007464-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN002828-PA 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" EDAN012777-PA 4 Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-975871 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane" EDAN000435-PA 2 MetaCyc: PWY-7560;KEGG: 00900+1.1.1.267 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" EDAN012173-PA 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" EDAN015191-PA 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" EDAN013038-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN005195-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN015802-PA 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" EDAN016744-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" EDAN000606-PA 17 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-5389840 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation elongation" EDAN008308-PA 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" EDAN018435-PA 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" EDAN004801-PA 20 MetaCyc: PWY-7574;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837 "Propanoyl-coa degradation II";"Peroxisomal protein import";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" EDAN009395-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN017986-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN012259-PA 1 Reactome: R-HSA-6783984 "Glycine degradation" EDAN009621-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN004925-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" EDAN016749-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN003052-PA 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" EDAN003142-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN006020-PA 13 KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220 "Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" EDAN006092-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" EDAN015486-PA 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" EDAN010864-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN016808-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN010763-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN013058-PA 4 MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23 "Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" EDAN000369-PA 2 Reactome: R-HSA-2453902;Reactome: R-HSA-2187335 "The canonical retinoid cycle in rods (twilight vision)";"The retinoid cycle in cones (daylight vision)" EDAN000043-PA 3 MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+1.3.98.1 "UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism" EDAN019250-PA 3 MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" EDAN008714-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006100-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" EDAN000563-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN013301-PA 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" EDAN017983-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN013193-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN010785-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN016631-PA 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" EDAN004411-PA 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" EDAN007425-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" EDAN000604-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN011368-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN018845-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN017464-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" EDAN000955-PA 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" EDAN007919-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" EDAN003413-PA 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" EDAN018337-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN018951-PA 10 KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "Carbon fixation in photosynthetic organisms";"Glycolysis";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" EDAN007304-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-390696;Reactome: R-HSA-416476 "G alpha (12/13) signalling events";"Adrenoceptors";"G alpha (q) signalling events" EDAN012620-PA 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events" EDAN004350-PA 7 MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052 "D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis" EDAN015451-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN009365-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN005983-PA 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" EDAN000141-PA 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" EDAN014783-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN018973-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" EDAN005949-PA 6 Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66 "Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system" EDAN006695-PA 2 Reactome: R-HSA-3772470;Reactome: R-HSA-201681 "Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT" EDAN001663-PA 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" EDAN008991-PA 14 MetaCyc: PWY-8051;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"Synthesis of PC";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Synthesis of PE";"Ether lipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis" EDAN018758-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" EDAN005435-PA 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" EDAN007617-PA 57 Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180534 "MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4" EDAN006642-PA 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" EDAN015389-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" EDAN018457-PA 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" EDAN015753-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" EDAN011383-PA 18 KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913 "Phenylalanine metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Arginine and proline metabolism";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)" EDAN010312-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN003424-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" EDAN010750-PA 6 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" EDAN019062-PA 1 Reactome: R-HSA-186797 "Signaling by PDGF" EDAN012171-PA 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" EDAN019573-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN002085-PA 10 Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424 "Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling" EDAN006067-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN007887-PA 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" EDAN006439-PA 7 Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" EDAN018724-PA 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" EDAN003449-PA 7 KEGG: 00670+3.5.1.10;KEGG: 00670+2.1.2.9;KEGG: 00630+3.5.1.10;KEGG: 00970+2.1.2.9;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-5497 "One carbon pool by folate";"One carbon pool by folate";"Glyoxylate and dicarboxylate metabolism";"Aminoacyl-tRNA biosynthesis";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)" EDAN000837-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" EDAN012870-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN010910-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN012709-PA 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" EDAN015765-PA 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" EDAN008148-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN007758-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" EDAN007105-PA 27 Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531 "SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus" EDAN013144-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" EDAN000285-PA 11 MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism" EDAN009519-PA 7 Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" EDAN016358-PA 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;Reactome: R-HSA-1362409 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" EDAN000077-PA 5 KEGG: 00270+3.3.1.1;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581 "Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation" EDAN008600-PA 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" EDAN012687-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN016746-PA 4 Reactome: R-HSA-3359478;Reactome: R-HSA-71032;Reactome: R-HSA-196741;Reactome: R-HSA-3359475 "Defective MUT causes methylmalonic aciduria mut type";"Propionyl-CoA catabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAA causes methylmalonic aciduria type cblA" EDAN008324-PA 9 KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7902 "Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis" EDAN013011-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" EDAN004311-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN000004-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" EDAN006667-PA 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;MetaCyc: PWY-6854;Reactome: R-HSA-8862803;Reactome: R-HSA-2151201 "Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Transcriptional activation of mitochondrial biogenesis" EDAN005814-PA 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" EDAN007834-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" EDAN016097-PA 2 Reactome: R-HSA-499943;KEGG: 00450+1.8.1.9 "Interconversion of nucleotide di- and triphosphates";"Selenocompound metabolism" EDAN005755-PA 16 MetaCyc: PWY-2221;MetaCyc: PWY-1622;MetaCyc: PWY-7124;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-5723 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Rubisco shunt" EDAN006727-PA 6 Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" EDAN018291-PA 13 KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" EDAN000907-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" EDAN017452-PA 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" EDAN003915-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" EDAN018180-PA 5 Reactome: R-HSA-3359467;Reactome: R-HSA-196741;Reactome: R-HSA-1614635;Reactome: R-HSA-3359469;Reactome: R-HSA-156581 "Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Sulfur amino acid metabolism";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Methylation" EDAN014292-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN006362-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" EDAN000041-PA 4 Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11 "Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism" EDAN014375-PA 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" EDAN019162-PA 4 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16 "Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism" EDAN017200-PA 5 MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7159;MetaCyc: PWY-7766 "3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)" EDAN014415-PA 4 Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" EDAN000322-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN014631-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination" EDAN011726-PA 10 MetaCyc: PWY-5853;MetaCyc: PWY-5839;MetaCyc: PWY-5892;KEGG: 00130+2.5.1.74;MetaCyc: PWY-5852;MetaCyc: PWY-7997;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5851;MetaCyc: PWY-5895 "Demethylmenaquinol-6 biosynthesis I";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Demethylmenaquinol-8 biosynthesis I";"Demethylmenaquinol-4 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Demethylmenaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis" EDAN011627-PA 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" EDAN002191-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" EDAN007287-PA 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" EDAN001517-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN018102-PA 12 Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606 "NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" EDAN016309-PA 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" EDAN016310-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" EDAN014402-PA 1 Reactome: R-HSA-420029 "Tight junction interactions" EDAN005485-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN014134-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN014760-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN019353-PA 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis" EDAN006770-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN011908-PA 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN006728-PA 6 Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" EDAN011932-PA 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" EDAN005218-PA 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" EDAN013264-PA 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" EDAN009527-PA 11 KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545 "Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN015066-PA 1 Reactome: R-HSA-8949613 "Cristae formation" EDAN009844-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN001767-PA 11 Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" EDAN013458-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" EDAN018550-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN016493-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN018246-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN000257-PA 27 MetaCyc: PWY-6901;KEGG: 00260+2.7.2.4;MetaCyc: PWY-2941;KEGG: 00260+5.4.2.12;MetaCyc: PWY-7003;MetaCyc: PWY-6886;KEGG: 00270+2.7.2.4;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-6559;MetaCyc: PWY-5723;MetaCyc: PWY-6160;KEGG: 00010+5.4.2.12;MetaCyc: PWY-8088;KEGG: 00680+5.4.2.12;MetaCyc: PWY-5097;MetaCyc: PWY-5484;MetaCyc: PWY-6562;MetaCyc: PWY-7153;MetaCyc: PWY-7977;MetaCyc: PWY-2221;MetaCyc: PWY-2942;KEGG: 00261+2.7.2.4;KEGG: 00300+2.7.2.4;Reactome: R-HSA-8964539;MetaCyc: PWY-7124;MetaCyc: PWY-6142 "Superpathway of glucose and xylose degradation";"Glycine, serine and threonine metabolism";"L-lysine biosynthesis II";"Glycine, serine and threonine metabolism";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Cysteine and methionine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Spermidine biosynthesis II";"Rubisco shunt";"3-dehydroquinate biosynthesis II (archaea)";"Glycolysis / Gluconeogenesis";"Dipicolinate biosynthesis";"Methane metabolism";"L-lysine biosynthesis VI";"Glycolysis II (from fructose 6-phosphate)";"Norspermidine biosynthesis";"Grixazone biosynthesis";"L-methionine biosynthesis IV (archaea)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-lysine biosynthesis III";"Monobactam biosynthesis";"Lysine biosynthesis";"Glutamate and glutamine metabolism";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" EDAN017921-PA 5 KEGG: 00400+4.2.1.20;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;KEGG: 00260+4.2.1.20 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation";"Glycine, serine and threonine metabolism" EDAN010820-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN008268-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN000130-PA 5 MetaCyc: PWY-5097;KEGG: 00300+1.17.1.8;MetaCyc: PWY-2941;MetaCyc: PWY-2942;KEGG: 00261+1.17.1.8 "L-lysine biosynthesis VI";"Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"Monobactam biosynthesis" EDAN007405-PA 5 Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571 "2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)" EDAN002293-PA 6 Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1 "Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch and sucrose metabolism" EDAN016397-PA 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human papillomavirus infection" EDAN003752-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" EDAN000252-PA 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" EDAN005925-PA 5 MetaCyc: PWY-4983;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39 "Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Arginine biosynthesis" EDAN013731-PA 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" EDAN015140-PA 13 MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN007827-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN009001-PA 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" EDAN003847-PA 9 Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome" EDAN012031-PA 4 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69205 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"G1/S-Specific Transcription" EDAN010650-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN013854-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN005336-PA 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" EDAN010861-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" EDAN008633-PA 22 Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5467340 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex" EDAN015017-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" EDAN000403-PA 5 Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism" EDAN008490-PA 19 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"LDL clearance";"Chylomicron remodeling";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"VLDL clearance";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"LDL remodeling";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors" EDAN003823-PA 5 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)" EDAN005661-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN004110-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" EDAN017571-PA 4 KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817 "Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" EDAN015689-PA 12 Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1169408 "Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"ISG15 antiviral mechanism" EDAN013588-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN019041-PA 6 MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.64;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660517 "3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane" EDAN003550-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" EDAN003225-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN003535-PA 10 Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1 "Ub-specific processing proteases";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"HATs acetylate histones";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection" EDAN011122-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN000458-PA 4 Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response";"Cristae formation" EDAN014459-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN003306-PA 3 MetaCyc: PWY-8074;KEGG: 00540+2.4.99.12;MetaCyc: PWY-7675 "Kdo transfer to lipid IVA IV (P. putida)";"Lipopolysaccharide biosynthesis";"Kdo transfer to lipid IVA II (Haemophilus)" EDAN001261-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN006766-PA 18 MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6 "Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes" EDAN011341-PA 18 Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238 "mRNA Capping";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" EDAN009108-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" EDAN018029-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN000759-PA 25 Reactome: R-HSA-8939245;Reactome: R-HSA-8935964;Reactome: R-HSA-8940973;Reactome: R-HSA-8877330;Reactome: R-HSA-8941284;Reactome: R-HSA-9616222;Reactome: R-HSA-8941326;Reactome: R-HSA-9018519;Reactome: R-HSA-8941858;Reactome: R-HSA-8941333;Reactome: R-HSA-8939243;Reactome: R-HSA-8939247;Reactome: R-HSA-8936459;Reactome: R-HSA-8941332;Reactome: R-HSA-8951936;Reactome: R-HSA-8939246;Reactome: R-HSA-8934593;Reactome: R-HSA-8939256;Reactome: R-HSA-8878166;Reactome: R-HSA-8931987;Reactome: R-HSA-8939236;Reactome: R-HSA-8949275;Reactome: R-HSA-8939902;Reactome: R-HSA-8939242;Reactome: R-HSA-8951911 "RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates osteoblast differentiation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates chondrocyte maturation";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates bone development";"Estrogen-dependent gene expression";"Regulation of RUNX3 expression and activity";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates genes involved in cell migration";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation by RUNX2";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX3 regulates RUNX1-mediated transcription" EDAN006430-PA 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" EDAN001068-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN013879-PA 7 KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614;Reactome: R-HSA-196757;Reactome: R-HSA-1474151 "One carbon pool by folate";"Folate transformations II (plants)";"Folate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" EDAN002958-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN011416-PA 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604 "Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling" EDAN017819-PA 6 MetaCyc: PWY-7980;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2 "ATP biosynthesis";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Oxidative phosphorylation";"Photosynthesis" EDAN019555-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN000414-PA 3 MetaCyc: PWY-7674;MetaCyc: PWY-1269;KEGG: 00540+2.5.1.55 "CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis" EDAN009059-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN008591-PA 6 Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-77588 "snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" EDAN016681-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN005316-PA 3 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN012883-PA 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" EDAN002255-PA 4 Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions" EDAN010442-PA 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" EDAN019345-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" EDAN017828-PA 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN011977-PA 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" EDAN018950-PA 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" EDAN005212-PA 35 Reactome: R-HSA-5621575;Reactome: R-HSA-380259;Reactome: R-HSA-4420097;Reactome: R-HSA-163615;Reactome: R-HSA-5610783;Reactome: R-HSA-9022692;KEGG: 04150+2.7.11.11;Reactome: R-HSA-180024;Reactome: R-HSA-512988;Reactome: R-HSA-381676;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-422356;Reactome: R-HSA-392517;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-380320;Reactome: R-HSA-432040;Reactome: R-HSA-8854518;Reactome: R-HSA-111931;Reactome: R-HSA-8853659;Reactome: R-HSA-163358;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-9010642;Reactome: R-HSA-5610780;Reactome: R-HSA-5578775;Reactome: R-HSA-5610787;Reactome: R-HSA-163560;Reactome: R-HSA-442720;Reactome: R-HSA-9022535;Reactome: R-HSA-2565942;Reactome: R-HSA-8963896;Reactome: R-HSA-9634600;Reactome: R-HSA-380284 "CD209 (DC-SIGN) signaling";"Loss of Nlp from mitotic centrosomes";"VEGFA-VEGFR2 Pathway";"PKA activation";"Degradation of GLI2 by the proteasome";"Regulation of MECP2 expression and activity";"mTOR signaling pathway";"DARPP-32 events";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of insulin secretion";"Rap1 signalling";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Recruitment of NuMA to mitotic centrosomes";"Vasopressin regulates renal water homeostasis via Aquaporins";"AURKA Activation by TPX2";"PKA-mediated phosphorylation of CREB";"RET signaling";"PKA-mediated phosphorylation of key metabolic factors";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"ROBO receptors bind AKAP5";"Degradation of GLI1 by the proteasome";"Ion homeostasis";"Hedgehog 'off' state";"Triglyceride catabolism";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Loss of phosphorylation of MECP2 at T308";"Regulation of PLK1 Activity at G2/M Transition";"HDL assembly";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Loss of proteins required for interphase microtubule organization from the centrosome" EDAN016654-PA 3 Reactome: R-HSA-983231;Reactome: R-HSA-6798695;Reactome: R-HSA-164944 "Factors involved in megakaryocyte development and platelet production";"Neutrophil degranulation";"Nef and signal transduction" EDAN002490-PA 6 KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis" EDAN006043-PA 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" EDAN007036-PA 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" EDAN006341-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN004682-PA 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" EDAN013150-PA 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" EDAN011005-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN000546-PA 18 MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes" EDAN003348-PA 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" EDAN002467-PA 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" EDAN004310-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" EDAN010896-PA 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" EDAN012496-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" EDAN011574-PA 5 MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" EDAN015236-PA 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" EDAN017341-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN005411-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN000333-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" EDAN004460-PA 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" EDAN008611-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN005665-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN005818-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" EDAN006811-PA 4 MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" EDAN018477-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN017221-PA 7 MetaCyc: PWY-6124;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7219 "Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis" EDAN003216-PA 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" EDAN013851-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN016526-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" EDAN011409-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN017974-PA 6 Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829 "Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" EDAN006974-PA 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" EDAN018478-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN009635-PA 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN014652-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN008131-PA 13 MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I" EDAN008388-PA 26 Reactome: R-HSA-6804114;Reactome: R-HSA-110314;Reactome: R-HSA-69205;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-110320;Reactome: R-HSA-174414;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-4615885;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-1362277;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-8866654;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174417 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Recognition of DNA damage by PCNA-containing replication complex";"G1/S-Specific Transcription";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Translesion Synthesis by POLH";"Processive synthesis on the C-strand of the telomere";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"SUMOylation of DNA replication proteins";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Transcription of E2F targets under negative control by DREAM complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"E3 ubiquitin ligases ubiquitinate target proteins";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis" EDAN010216-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN009850-PA 13 KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-5497;KEGG: 00670+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841 "Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)" EDAN017393-PA 10 Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201 "Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis" EDAN000556-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN010984-PA 33 Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation" EDAN003205-PA 1 KEGG: 00340+4.2.1.19 "Histidine metabolism" EDAN009893-PA 5 MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" EDAN009791-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN007835-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" EDAN014974-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" EDAN007927-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN005517-PA 3 KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691 "Caffeine metabolism";"Purine metabolism";"Urate conversion to allantoin I" EDAN004352-PA 13 KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871809;Reactome: R-HSA-202433;Reactome: R-HSA-2029485;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11 "Inositol phosphate metabolism";"FCERI mediated Ca+2 mobilization";"Generation of second messenger molecules";"Role of phospholipids in phagocytosis";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" EDAN003014-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" EDAN011578-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination" EDAN003400-PA 3 Reactome: R-HSA-114608;MetaCyc: PWY-6308;KEGG: 00970+6.1.1.3 "Platelet degranulation";"L-cysteine biosynthesis II (tRNA-dependent)";"Aminoacyl-tRNA biosynthesis" EDAN014998-PA 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" EDAN013154-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN002398-PA 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" EDAN005466-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN001294-PA 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" EDAN018690-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" EDAN013100-PA 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" EDAN013822-PA 8 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin" EDAN004680-PA 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" EDAN008512-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN006789-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN002252-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN011720-PA 5 Reactome: R-HSA-196757;MetaCyc: PWY-6614;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3 "Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"One carbon pool by folate";"Folate biosynthesis" EDAN011884-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" EDAN004103-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance" EDAN005727-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN017122-PA 18 MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism" EDAN000146-PA 8 KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5340;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4 "Monobactam biosynthesis";"Sulfur metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Purine metabolism";"Selenocompound metabolism" EDAN011278-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" EDAN016468-PA 5 Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1483115;Reactome: R-HSA-1482788 "Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Hydrolysis of LPC";"Acyl chain remodelling of PC" EDAN011670-PA 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" EDAN000391-PA 3 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN012469-PA 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-8055;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA" EDAN018593-PA 3 Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Respiratory electron transport";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)" EDAN015180-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN015061-PA 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" EDAN011528-PA 1 Reactome: R-HSA-3295583 "TRP channels" EDAN010800-PA 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" EDAN003272-PA 16 Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-5419276;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Mitochondrial translation termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation elongation" EDAN014576-PA 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" EDAN013930-PA 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" EDAN018599-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN012646-PA 13 Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-6545 "Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN016064-PA 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" EDAN008210-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN004936-PA 1 Reactome: R-HSA-977443 "GABA receptor activation" EDAN018441-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN013858-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" EDAN017071-PA 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" EDAN003391-PA 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" EDAN015878-PA 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" EDAN010136-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN003011-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN000461-PA 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" EDAN002317-PA 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" EDAN014695-PA 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" EDAN009533-PA 6 KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;Reactome: R-HSA-446210;MetaCyc: PWY-7077 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation" EDAN009617-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN005289-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN006514-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" EDAN007566-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN003813-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" EDAN010627-PA 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6" EDAN018586-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" EDAN004868-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN000653-PA 4 MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199;Reactome: R-HSA-4755583 "Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)" EDAN006697-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" EDAN013281-PA 10 KEGG: 00650+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781 "Butanoate metabolism";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"PPARA activates gene expression" EDAN013745-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN006644-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" EDAN004924-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" EDAN000002-PA 7 Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6605;MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610 "Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Purine metabolism";"Adenine salvage" EDAN012920-PA 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" EDAN005667-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN004185-PA 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" EDAN000367-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN002069-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" EDAN004546-PA 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" EDAN015981-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN009359-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" EDAN006687-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN017742-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN014863-PA 10 Reactome: R-HSA-70171;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;MetaCyc: PWY-6142 "Glycolysis";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" EDAN013031-PA 9 Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-241 "Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" EDAN004248-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN005672-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN012365-PA 11 Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2022928 "Defective EXT2 causes exostoses 2";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG biosynthesis" EDAN013791-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" EDAN005673-PA 10 MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263 "Glycerol degradation to butanol";"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis" EDAN000111-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN002066-PA 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" EDAN014311-PA 20 Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-3371571;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-1257604 "TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Thermogenesis";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"HSF1-dependent transactivation";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"Macroautophagy";"mTORC1-mediated signalling";"PIP3 activates AKT signaling" EDAN014064-PA 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" EDAN006168-PA 4 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" EDAN013199-PA 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" EDAN004023-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN015746-PA 5 Reactome: R-HSA-1482922;Reactome: R-HSA-1483115;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1482839 "Acyl chain remodelling of PI";"Hydrolysis of LPC";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Acyl chain remodelling of PE" EDAN013599-PA 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" EDAN018622-PA 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism" EDAN010573-PA 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" EDAN010835-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" EDAN005227-PA 10 Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-9648895;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72731;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "ABC-family proteins mediated transport";"PERK regulates gene expression";"Response of EIF2AK1 (HRI) to heme deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Recycling of eIF2:GDP";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" EDAN003709-PA 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" EDAN000808-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" EDAN008281-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" EDAN013208-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN016497-PA 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" EDAN017948-PA 3 KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403 "Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling" EDAN012704-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN007396-PA 13 KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "Thermogenesis";"EPHB-mediated forward signaling";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"G alpha (q) signalling events";"Human papillomavirus infection";"NRAGE signals death through JNK";"Relaxin signaling pathway";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"G alpha (12/13) signalling events" EDAN000625-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN017197-PA 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" EDAN010858-PA 4 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Pyruvate metabolism";"Aminobenzoate degradation";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" EDAN008190-PA 20 MetaCyc: PWY-7288;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7858 "Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II" EDAN013189-PA 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" EDAN006094-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" EDAN003430-PA 10 Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-9627069 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity" EDAN000098-PA 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" EDAN016025-PA 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" EDAN016735-PA 11 MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381 "Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)" EDAN014047-PA 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" EDAN005679-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN002268-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN003309-PA 2 MetaCyc: PWY-7883;Reactome: R-HSA-196757 "Anhydromuropeptides recycling II";"Metabolism of folate and pterines" EDAN014302-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" EDAN016872-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN001119-PA 5 MetaCyc: PWY-7782;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896 "Plasmalogen biosynthesis";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis" EDAN010536-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN007117-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN018089-PA 5 KEGG: 00520+2.5.1.7;KEGG: 00550+2.5.1.7;MetaCyc: PWY-6386;MetaCyc: PWY-6387;MetaCyc: PWY-7953 "Amino sugar and nucleotide sugar metabolism";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)" EDAN005317-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN003191-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN002979-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN001410-PA 33 Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690 "Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events" EDAN004153-PA 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" EDAN000211-PA 1 Reactome: R-HSA-8935690 "Digestion" EDAN019303-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN015369-PA 3 Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis" EDAN017439-PA 10 Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" EDAN009061-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" EDAN004046-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN016676-PA 5 Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" EDAN015187-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN002927-PA 14 KEGG: 00562+3.1.4.11;Reactome: R-HSA-500657;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-434316 "Inositol phosphate metabolism";"Presynaptic function of Kainate receptors";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" EDAN007673-PA 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" EDAN016958-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN002121-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" EDAN000113-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN018689-PA 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" EDAN005723-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN001478-PA 6 Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" EDAN006352-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN003399-PA 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" EDAN000121-PA 10 MetaCyc: PWY-5895;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5891;Reactome: R-HSA-2142789;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5839;MetaCyc: PWY-5844 "Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-9 biosynthesis" EDAN003577-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" EDAN008444-PA 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" EDAN000405-PA 4 MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41 "L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis" EDAN004289-PA 10 MetaCyc: PWY-5895;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5844;MetaCyc: PWY-5839 "Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis" EDAN013026-PA 18 Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6807505 "Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes" EDAN005484-PA 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" EDAN018300-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" EDAN000207-PA 3 Reactome: R-HSA-5362517;Reactome: R-HSA-70895;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN008628-PA 4 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" EDAN014687-PA 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human papillomavirus infection" EDAN014428-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" EDAN006620-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" EDAN018851-PA 4 KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1 "Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism" EDAN008025-PA 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN002179-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" EDAN000198-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN019541-PA 8 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Relaxin signaling pathway";"Human papillomavirus infection" EDAN000351-PA 3 Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" EDAN017995-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN016692-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" EDAN014466-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN011751-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN000339-PA 4 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis" EDAN002827-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" EDAN016800-PA 13 KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" EDAN005453-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN003357-PA 2 MetaCyc: PWY-5514;KEGG: 00520+2.3.1.157+2.7.7.23 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism" EDAN002651-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN003689-PA 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" EDAN014761-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN007195-PA 3 Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760 "PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation" EDAN011288-PA 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" EDAN018551-PA 21 MetaCyc: PWY-6722;MetaCyc: PWY-2941;KEGG: 00260+2.7.2.4;MetaCyc: PWY-5744;KEGG: 00270+2.7.2.4;MetaCyc: PWY-8088;MetaCyc: PWY-6160;MetaCyc: PWY-5743;MetaCyc: PWY-6559;MetaCyc: PWY-5097;MetaCyc: PWY-5789;MetaCyc: PWY-7977;KEGG: 00970+6.1.1.16;MetaCyc: PWY-7153;MetaCyc: PWY-6562;Reactome: R-HSA-8964539;Reactome: R-HSA-196780;KEGG: 00261+2.7.2.4;MetaCyc: PWY-2942;KEGG: 00300+2.7.2.4;MetaCyc: PWY-4381 "Candicidin biosynthesis";"L-lysine biosynthesis II";"Glycine, serine and threonine metabolism";"Glyoxylate assimilation";"Cysteine and methionine metabolism";"Dipicolinate biosynthesis";"3-dehydroquinate biosynthesis II (archaea)";"3-hydroxypropanoate cycle";"Spermidine biosynthesis II";"L-lysine biosynthesis VI";"3-hydroxypropanoate/4-hydroxybutanate cycle";"L-methionine biosynthesis IV (archaea)";"Aminoacyl-tRNA biosynthesis";"Grixazone biosynthesis";"Norspermidine biosynthesis";"Glutamate and glutamine metabolism";"Biotin transport and metabolism";"Monobactam biosynthesis";"L-lysine biosynthesis III";"Lysine biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)" EDAN018345-PA 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" EDAN008886-PA 2 KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" EDAN011716-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN015868-PA 12 MetaCyc: PWY-7901;MetaCyc: PWY-601;MetaCyc: PWY-6842;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-6936;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-801 "Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Homocysteine and cysteine interconversion" EDAN004944-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN011008-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" EDAN009818-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN007212-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" EDAN004468-PA 5 Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends" EDAN010788-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN000791-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN005653-PA 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" EDAN007683-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN010552-PA 9 Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" EDAN016747-PA 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" EDAN008865-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" EDAN015688-PA 12 Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-429947 "ISG15 antiviral mechanism";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA" EDAN000596-PA 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-5419276;Reactome: R-HSA-9010553;Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-5389840;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial translation termination";"Regulation of expression of SLITs and ROBOs";"Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" EDAN003655-PA 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" EDAN009149-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN015352-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" EDAN005032-PA 16 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" EDAN013388-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006234-PA 11 Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-163615 "PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation" EDAN013999-PA 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" EDAN002439-PA 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" EDAN011415-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN014521-PA 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833 "ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)" EDAN012391-PA 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" EDAN010935-PA 9 MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle" EDAN017518-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN000375-PA 2 MetaCyc: PWY-8073;KEGG: 00540+3.6.1.54 "Lipid IVA biosynthesis (P. putida)";"Lipopolysaccharide biosynthesis" EDAN016603-PA 4 MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" EDAN008216-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" EDAN004074-PA 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" EDAN004626-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN019436-PA 4 MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" EDAN000456-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN012768-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN015210-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN000266-PA 2 KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Methane metabolism";"Glycine, serine and threonine metabolism" EDAN001117-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" EDAN017132-PA 9 MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029 "3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide" EDAN012692-PA 5 MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32 "Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" EDAN018338-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN015682-PA 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" EDAN003420-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN000415-PA 11 Reactome: R-HSA-5362517;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-204174;Reactome: R-HSA-68689;Reactome: R-HSA-70895;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949 "Signaling by Retinoic Acid";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Regulation of pyruvate dehydrogenase (PDH) complex";"CDC6 association with the ORC:origin complex";"Branched-chain amino acid catabolism";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin" EDAN007144-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN019510-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN017803-PA 7 Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-381070 "Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"IRE1alpha activates chaperones" EDAN006894-PA 5 Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"EPHB-mediated forward signaling" EDAN001993-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" EDAN003310-PA 11 MetaCyc: PWY-1281;KEGG: 00430+2.3.1.8;KEGG: 00640+2.3.1.8;KEGG: 00620+2.3.1.8;KEGG: 00680+2.3.1.8;MetaCyc: PWY-5482;MetaCyc: PWY-5485;MetaCyc: PWY-8086;MetaCyc: PWY-6637;KEGG: 00720+2.3.1.8;MetaCyc: PWY-5497 "Sulfoacetaldehyde degradation I";"Taurine and hypotaurine metabolism";"Propanoate metabolism";"Pyruvate metabolism";"Methane metabolism";"Pyruvate fermentation to acetate II";"Pyruvate fermentation to acetate IV";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Sulfolactate degradation II";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)" EDAN014273-PA 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" EDAN005144-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" EDAN000112-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN000037-PA 9 KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-6901;Reactome: R-HSA-70171 "Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis" EDAN003469-PA 5 Reactome: R-HSA-6798695;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24 "Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" EDAN003610-PA 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" EDAN012605-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" EDAN007998-PA 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" EDAN019233-PA 1 MetaCyc: PWY-101 "Photosynthesis light reactions" EDAN006239-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN000135-PA 6 MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11 "Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism" EDAN019545-PA 2 Reactome: R-HSA-1296072;MetaCyc: PWY-6308 "Voltage gated Potassium channels";"L-cysteine biosynthesis II (tRNA-dependent)" EDAN012301-PA 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" EDAN015477-PA 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" EDAN012437-PA 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" EDAN004905-PA 15 Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692 "Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity" EDAN000857-PA 2 Reactome: R-HSA-5656169;Reactome: R-HSA-6807505 "Termination of translesion DNA synthesis";"RNA polymerase II transcribes snRNA genes" EDAN013086-PA 5 Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757 "CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation" EDAN018737-PA 10 Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897 "Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes" EDAN016935-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN014990-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" EDAN013035-PA 13 MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" EDAN005631-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN012124-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN003240-PA 5 MetaCyc: PWY-7953;KEGG: 00520+1.3.1.98;MetaCyc: PWY-6387;KEGG: 00550+1.3.1.98;MetaCyc: PWY-6386 "UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)" EDAN014868-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN004741-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN007237-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" EDAN005378-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN008606-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN009266-PA 10 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance" EDAN013186-PA 13 Reactome: R-HSA-382556;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725;Reactome: R-HSA-532668 "ABC-family proteins mediated transport";"Aggrephagy";"Josephin domain DUBs";"Ovarian tumor domain proteases";"HSF1 activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" EDAN008089-PA 11 Reactome: R-HSA-8862803;Reactome: R-HSA-5617472;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-8943724;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-5687128 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of PTEN gene transcription";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"MAPK6/MAPK4 signaling" EDAN006914-PA 9 Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867 "CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex" EDAN007640-PA 5 Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148;Reactome: R-HSA-6798695 "Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation" EDAN002505-PA 3 Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" EDAN004010-PA 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" EDAN019470-PA 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism" EDAN015575-PA 14 MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Sciadonate biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" EDAN011586-PA 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" EDAN009390-PA 7 Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795 "SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity" EDAN000312-PA 6 MetaCyc: PWY-5664;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442 "Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis" EDAN001123-PA 3 Reactome: R-HSA-4086400;Reactome: R-HSA-373080;Reactome: R-HSA-4608870 "PCP/CE pathway";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins" EDAN009787-PA 12 Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6804756 "Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation" EDAN006574-PA 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" EDAN017915-PA 3 MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" EDAN014155-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" EDAN004927-PA 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" EDAN006144-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN000314-PA 14 Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5685942 "PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)" EDAN003993-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" EDAN013897-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN002167-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN000908-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" EDAN015400-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" EDAN014499-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN013039-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN014240-PA 7 Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300 "Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" EDAN012550-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" EDAN018768-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN004139-PA 5 Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670 "Glycosphingolipid metabolism";"MHC class II antigen presentation";"Neutrophil degranulation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis" EDAN010447-PA 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" EDAN012649-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN009584-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" EDAN002668-PA 1 Reactome: R-HSA-8876725 "Protein methylation" EDAN001759-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN000958-PA 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" EDAN017705-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN013965-PA 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN008992-PA 20 Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-69473 "HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint" EDAN019596-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN019532-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN017825-PA 17 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" EDAN011668-PA 8 KEGG: 00740+2.7.1.26+2.7.7.2;MetaCyc: PWY-6167;Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;KEGG: 00740+2.7.7.2;MetaCyc: PWY-6168;MetaCyc: PWY-7863 "Riboflavin metabolism";"Flavin biosynthesis II (archaea)";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis" EDAN005610-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN018130-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN018034-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN001979-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN003184-PA 6 MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-4381 "Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)" EDAN003675-PA 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" EDAN007065-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN001535-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN019567-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN003226-PA 15 MetaCyc: PWY-181;MetaCyc: PWY-2201;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00460+2.1.2.1;Reactome: R-HSA-499943;MetaCyc: PWY-3841;KEGG: 00670+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;MetaCyc: PWY-3661;MetaCyc: PWY-2161 "Photorespiration ";"Folate transformations I";"Methane metabolism";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Cyanoamino acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Folate transformations II (plants)";"One carbon pool by folate";"Glyoxylate and dicarboxylate metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I";"Folate polyglutamylation" EDAN004623-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN007190-PA 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor" EDAN006870-PA 1 Reactome: R-HSA-1483101 "Synthesis of PS" EDAN014314-PA 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" EDAN010966-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" EDAN001250-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN014580-PA 25 Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-380270;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736 "Cilium Assembly";"Aggrephagy";"HCMV Early Events";"Recruitment of mitotic centrosome proteins and complexes";"Mitotic Prometaphase";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors" EDAN004424-PA 33 Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214 "Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins" EDAN002735-PA 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" EDAN012433-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" EDAN018996-PA 2 MetaCyc: PWY-8106;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" EDAN015896-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN013046-PA 28 Reactome: R-HSA-6782210;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696395;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Formation of Incision Complex in GG-NER";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI" EDAN003432-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN017808-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" EDAN013504-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" EDAN001580-PA 5 Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-9608290;Reactome: R-HSA-9608287;Reactome: R-HSA-110331 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate processing";"Defective MUTYH substrate binding";"Cleavage of the damaged purine" EDAN017886-PA 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" EDAN006828-PA 4 Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258 "Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" EDAN001315-PA 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" EDAN019035-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN000559-PA 9 Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-7377;MetaCyc: PWY-5188;KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107;Reactome: R-HSA-5358493;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5196;MetaCyc: PWY-5194 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Cob(ii)yrinate a,c-diamide biosynthesis I (early cobalt insertion)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Synthesis of diphthamide-EEF2";"Porphyrin and chlorophyll metabolism";"Factor 430 biosynthesis";"Siroheme biosynthesis" EDAN017663-PA 14 MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51 "Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism" EDAN014293-PA 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex" EDAN019523-PA 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" EDAN004943-PA 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" EDAN004360-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN017839-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN008024-PA 9 Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789 "TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" EDAN011307-PA 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" EDAN008478-PA 13 Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-2871809 "Effects of PIP2 hydrolysis";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization" EDAN000064-PA 3 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2 "ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis" EDAN003696-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN018086-PA 2 KEGG: 00770+2.7.7.3;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" EDAN000394-PA 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" EDAN011408-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" EDAN008528-PA 4 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" EDAN016338-PA 4 KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004 "Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I" EDAN003304-PA 11 MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-6549;MetaCyc: PWY-7124;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913 "TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)" EDAN009783-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN001088-PA 4 KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" EDAN015060-PA 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" EDAN000821-PA 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" EDAN005635-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN003491-PA 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" EDAN010613-PA 4 KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475 "Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis" EDAN012766-PA 7 KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III" EDAN005543-PA 7 Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346 "Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis" EDAN017483-PA 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" EDAN018954-PA 1 Reactome: R-HSA-400253 "Circadian Clock" EDAN007657-PA 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" EDAN000396-PA 16 MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-7218;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-7124;MetaCyc: PWY-1622;MetaCyc: PWY-2221 "Rubisco shunt";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Ethylene biosynthesis V (engineered)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)" EDAN000480-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" EDAN000816-PA 2 Reactome: R-HSA-1299308;Reactome: R-HSA-5576886 "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential" EDAN000780-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN001073-PA 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression" EDAN012323-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN018532-PA 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" EDAN009208-PA 10 MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15 "Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" EDAN003406-PA 11 MetaCyc: PWY-5103;KEGG: 00290+2.2.1.6;MetaCyc: PWY-5101;KEGG: 00770+2.2.1.6;KEGG: 00650+2.2.1.6;MetaCyc: PWY-5104;MetaCyc: PWY-6389;MetaCyc: PWY-5939;MetaCyc: PWY-5938;MetaCyc: PWY-7111;KEGG: 00660+2.2.1.6 "L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"Pantothenate and CoA biosynthesis";"Butanoate metabolism";"L-isoleucine biosynthesis IV";"Pyruvate fermentation to (S)-acetoin";"Pyruvate fermentation to (R)-acetoin II";"Pyruvate fermentation to (R)-acetoin I";"Pyruvate fermentation to isobutanol (engineered)";"C5-Branched dibasic acid metabolism" EDAN010506-PA 9 MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902 "Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)" EDAN015827-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN004875-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN005035-PA 6 Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781 "Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"PPARA activates gene expression" EDAN013620-PA 8 Reactome: R-HSA-6798695;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463 "Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs" EDAN014564-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN008001-PA 1 Reactome: R-HSA-418990 "Adherens junctions interactions" EDAN017120-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN003498-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN010862-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN019053-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN003315-PA 10 MetaCyc: PWY-6907;MetaCyc: PWY-7356;KEGG: 00730+2.5.1.3;MetaCyc: PWY-7357;MetaCyc: PWY-6897;MetaCyc: PWY-6893;MetaCyc: PWY-6908;KEGG: 00860+5.4.3.8;MetaCyc: PWY-6894;MetaCyc: PWY-5188 "Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine formation from pyrithiamine and oxythiamine (yeast)";"Thiamine salvage II";"Thiamine diphosphate biosynthesis II (Bacillus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Porphyrin and chlorophyll metabolism";"Thiamine diphosphate biosynthesis I (E. coli)";"Tetrapyrrole biosynthesis I (from glutamate)" EDAN019474-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN012039-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN004448-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" EDAN001756-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN017271-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN004003-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" EDAN017262-PA 9 KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism" EDAN003121-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" EDAN011684-PA 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" EDAN002901-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" EDAN007682-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN015974-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN005583-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" EDAN004376-PA 7 MetaCyc: PWY-6605;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7805;MetaCyc: PWY-6610;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807 "Adenine and adenosine salvage II";"Purine salvage";"Neutrophil degranulation";"(aminomethyl)phosphonate degradation";"Adenine salvage";"Purine metabolism";"Glyphosate degradation III" EDAN007215-PA 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" EDAN005425-PA 13 KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1 "Drug metabolism - other enzymes";"Ascorbate glutathione cycle";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Glutathione metabolism" EDAN008455-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN017734-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN001398-PA 13 Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Integrin cell surface interactions";"Signaling by PDGF";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Laminin interactions";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" EDAN007123-PA 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" EDAN019568-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN015299-PA 3 MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51 "Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation" EDAN003681-PA 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" EDAN019336-PA 11 KEGG: 00670+2.1.1.13;MetaCyc: PWY-3841;Reactome: R-HSA-156581;Reactome: R-HSA-1614635;Reactome: R-HSA-3359467;Reactome: R-HSA-196741;MetaCyc: PWY-2201;MetaCyc: PWY-7977;Reactome: R-HSA-3359469;KEGG: 00270+2.1.1.13;KEGG: 00450+2.1.1.13 "One carbon pool by folate";"Folate transformations II (plants)";"Methylation";"Sulfur amino acid metabolism";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Folate transformations I";"L-methionine biosynthesis IV (archaea)";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Cysteine and methionine metabolism";"Selenocompound metabolism" EDAN008316-PA 1 Reactome: R-HSA-75153 "Apoptotic execution phase" EDAN002889-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN002656-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN017327-PA 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" EDAN016444-PA 1 Reactome: R-HSA-5578775 "Ion homeostasis" EDAN004395-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN018739-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN012306-PA 1 Reactome: R-HSA-74217 "Purine salvage" EDAN016997-PA 20 MetaCyc: PWY-7288;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7858 "Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II" EDAN002528-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN018105-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN013316-PA 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" EDAN001070-PA 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221 "Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway" EDAN007379-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" EDAN006601-PA 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" EDAN006643-PA 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" EDAN005271-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" EDAN011993-PA 56 Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154 "FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin" EDAN006522-PA 1 Reactome: R-HSA-376172 "DSCAM interactions" EDAN015030-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN009794-PA 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" EDAN012494-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN012589-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" EDAN014303-PA 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" EDAN013179-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" EDAN010298-PA 16 KEGG: 00254+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-6679;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168 "Aflatoxin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Jadomycin biosynthesis";"Carnitine metabolism";"Pyruvate metabolism";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)" EDAN015966-PA 4 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" EDAN013739-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" EDAN009521-PA 13 Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038 "MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"LDL clearance" EDAN005939-PA 1 Reactome: R-HSA-3295583 "TRP channels" EDAN017993-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN018667-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN014667-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN004996-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN016149-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" EDAN008124-PA 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" EDAN014908-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN011352-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" EDAN003289-PA 12 MetaCyc: PWY-5872;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5871 "Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)" EDAN010585-PA 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" EDAN005815-PA 3 KEGG: 00400+4.2.1.20;KEGG: 00260+4.2.1.20;KEGG: 00400+5.3.1.24 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Glycine, serine and threonine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN013826-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN001976-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN009736-PA 4 MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" EDAN000241-PA 1 Reactome: R-HSA-156581 "Methylation" EDAN003270-PA 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" EDAN016472-PA 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" EDAN002838-PA 1 Reactome: R-HSA-211981 "Xenobiotics" EDAN002385-PA 13 KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-7709 "Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis" EDAN003088-PA 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation" EDAN005463-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN001718-PA 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206291;Reactome: R-HSA-6798695 "HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation" EDAN006658-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN013157-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN017029-PA 6 Reactome: R-HSA-8874081;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216 "MET activates PTK2 signaling";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization" EDAN015398-PA 3 Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" EDAN016951-PA 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" EDAN002811-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" EDAN003984-PA 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" EDAN002440-PA 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" EDAN018208-PA 5 Reactome: R-HSA-5368286;KEGG: 00970+6.1.1.20;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-379716 "Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Cytosolic tRNA aminoacylation" EDAN017392-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN010596-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" EDAN005547-PA 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" EDAN002330-PA 4 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" EDAN006031-PA 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" EDAN001553-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN014480-PA 6 Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483 "Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1" EDAN011544-PA 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis" EDAN003224-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN005845-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN018635-PA 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" EDAN000325-PA 6 MetaCyc: PWY-5104;MetaCyc: PWY-7111;KEGG: 00290+4.2.1.9;KEGG: 00770+4.2.1.9;MetaCyc: PWY-5103;MetaCyc: PWY-5101 "L-isoleucine biosynthesis IV";"Pyruvate fermentation to isobutanol (engineered)";"Valine, leucine and isoleucine biosynthesis";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II" EDAN001236-PA 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" EDAN018589-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN011694-PA 2 Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66 "Purine catabolism";"Purine metabolism" EDAN017546-PA 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" EDAN005849-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN001472-PA 2 Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Pyrimidine salvage";"Pyrimidine catabolism" EDAN002447-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN000679-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN007235-PA 5 Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221 "RAF activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway" EDAN014386-PA 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" EDAN010531-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN016756-PA 18 Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4 "Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Ether lipid metabolism" EDAN001964-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" EDAN010244-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" EDAN016006-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN000883-PA 10 KEGG: 00998+5.4.2.9;MetaCyc: PWY-6839;MetaCyc: PWY-8067;MetaCyc: PWY-7419;KEGG: 00440+5.4.2.9;MetaCyc: PWY-7769;MetaCyc: PWY-6322;MetaCyc: PWY-7510;MetaCyc: PWY-6682;MetaCyc: PWY-5757 "Biosynthesis of various secondary metabolites - part 2";"2-aminoethylphosphonate biosynthesis";"Methylphosphonate biosynthesis";"FR-900098 and FR-33289 antibiotics biosynthesis";"Phosphonate and phosphinate metabolism";"Phosalacine biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Rhizocticin A and B biosynthesis";"Dehydrophos biosynthesis";"Fosfomycin biosynthesis" EDAN001670-PA 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" EDAN005810-PA 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" EDAN012964-PA 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" EDAN000460-PA 9 MetaCyc: PWY-7342;MetaCyc: PWY-5653;KEGG: 00760+2.4.2.19;MetaCyc: PWY-5381;KEGG: 00970+6.1.1.9;MetaCyc: PWY-5316;Reactome: R-HSA-196807;KEGG: 00760+6.3.4.21;Reactome: R-HSA-379716 "Superpathway of nicotine biosynthesis";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Aminoacyl-tRNA biosynthesis";"Nicotine biosynthesis";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Cytosolic tRNA aminoacylation" EDAN013918-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN009776-PA 18 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783 "Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation" EDAN012373-PA 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" EDAN010857-PA 11 KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-5381;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-7821 "Purine metabolism";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis" EDAN004298-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN010478-PA 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" EDAN000443-PA 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" EDAN007563-PA 8 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy" EDAN001704-PA 1 Reactome: R-HSA-437239 "Recycling pathway of L1" EDAN014552-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" EDAN019040-PA 4 KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281 "Selenocompound metabolism";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" EDAN000553-PA 4 Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" EDAN002090-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN005901-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" EDAN003631-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN002825-PA 10 Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695 "Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"MPS VII - Sly syndrome";"Other glycan degradation";"Glycosaminoglycan degradation";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Neutrophil degranulation" EDAN008929-PA 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" EDAN009315-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN011179-PA 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" EDAN011205-PA 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN019047-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN011158-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" EDAN004763-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN004020-PA 8 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection" EDAN003379-PA 8 KEGG: 00997+2.3.1.30;MetaCyc: PWY-6936;MetaCyc: PWY-8071;MetaCyc: PWY-7274;KEGG: 00270+2.3.1.30;KEGG: 00920+2.3.1.30;Reactome: R-HSA-446205;MetaCyc: PWY-7870 "Biosynthesis of various secondary metabolites - part 3";"Seleno-amino acid biosynthesis (plants)";"N-3-oxalyl-L-2,3-diaminopropanoate biosynthesis";"D-cycloserine biosynthesis";"Cysteine and methionine metabolism";"Sulfur metabolism";"Synthesis of GDP-mannose";"L-cysteine biosynthesis VII (from S-sulfo-L-cysteine)" EDAN019114-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" EDAN011557-PA 4 MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage" EDAN001942-PA 40 Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-5617472;Reactome: R-HSA-167160;Reactome: R-HSA-5578749;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-72163 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway" EDAN012382-PA 3 MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN002574-PA 24 Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148 "MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Aggrephagy";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Recycling pathway of L1";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" EDAN002607-PA 10 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription" EDAN006542-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN013440-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" EDAN015828-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN005782-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN014353-PA 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" EDAN012122-PA 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" EDAN008957-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" EDAN012969-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN001371-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" EDAN017690-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN004896-PA 8 Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-2301;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372 "Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" EDAN014355-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN005408-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" EDAN000421-PA 5 MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism" EDAN002620-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN006945-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN003118-PA 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" EDAN000884-PA 7 MetaCyc: PWY-46;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-4984;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1 "Putrescine biosynthesis III";"Urea cycle";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Canavanine degradation";"Arginine biosynthesis" EDAN013971-PA 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" EDAN011235-PA 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" EDAN002621-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN007985-PA 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" EDAN018831-PA 14 MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWYG-321;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100;MetaCyc: PWY-5367;KEGG: 00780+1.1.1.100;MetaCyc: PWY-6519;MetaCyc: PWY-6282 "(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Biotin metabolism";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)" EDAN003105-PA 5 KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660499 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane" EDAN000917-PA 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" EDAN013665-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" EDAN007035-PA 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" EDAN009263-PA 8 Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" EDAN006671-PA 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLI" EDAN014774-PA 13 MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-6545 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN015058-PA 7 MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-6840 "Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis" EDAN000468-PA 4 MetaCyc: PWY-7902;KEGG: 00500+2.7.7.27;KEGG: 00520+2.7.7.27;MetaCyc: PWY-622 "Glucosylglycerol biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch biosynthesis" EDAN004843-PA 9 Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" EDAN011760-PA 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes" EDAN006669-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN013563-PA 3 Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117 "O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis" EDAN009071-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN015179-PA 1 Reactome: R-HSA-71288 "Creatine metabolism" EDAN009400-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" EDAN015407-PA 13 MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN018204-PA 7 KEGG: 00620+2.3.3.13;MetaCyc: PWY-5103;KEGG: 00770+1.1.1.86;KEGG: 00290+2.3.3.13;MetaCyc: PWY-6871;KEGG: 00290+1.1.1.86;MetaCyc: PWY-7111 "Pyruvate metabolism";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"3-methylbutanol biosynthesis (engineered)";"Valine, leucine and isoleucine biosynthesis";"Pyruvate fermentation to isobutanol (engineered)" EDAN003371-PA 24 Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436 "Cilium Assembly";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic" EDAN013666-PA 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" EDAN012330-PA 3 MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807 "Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis" EDAN000265-PA 10 Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568 "SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN012450-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" EDAN006171-PA 12 Reactome: R-HSA-3371497;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380259 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes" EDAN003198-PA 5 Reactome: R-HSA-110357;Reactome: R-HSA-9608287;Reactome: R-HSA-9608290;Reactome: R-HSA-110330;Reactome: R-HSA-110331 "Displacement of DNA glycosylase by APEX1";"Defective MUTYH substrate binding";"Defective MUTYH substrate processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine" EDAN016842-PA 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" EDAN007584-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN000278-PA 4 Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250 "Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis" EDAN000412-PA 1 KEGG: 00540+2.7.7.70+2.7.1.167 "Lipopolysaccharide biosynthesis" EDAN005500-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" EDAN012847-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN013756-PA 3 MetaCyc: PWY-7761;KEGG: 00760+3.6.1.22;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" EDAN003975-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN013653-PA 1 Reactome: R-HSA-8963684 "Tyrosine catabolism" EDAN001043-PA 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" EDAN014562-PA 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" EDAN008158-PA 179 Reactome: R-HSA-2173791;Reactome: R-HSA-5654733;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-2894862;Reactome: R-HSA-5610785;Reactome: R-HSA-936964;Reactome: R-HSA-4641258;Reactome: R-HSA-450302;Reactome: R-HSA-72764;Reactome: R-HSA-168928;Reactome: R-HSA-209543;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-8856825;Reactome: R-HSA-5675482;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9613829;Reactome: R-HSA-2559580;Reactome: R-HSA-5632684;Reactome: R-HSA-400253;Reactome: R-HSA-2467813;Reactome: R-HSA-192823;Reactome: R-HSA-975110;Reactome: R-HSA-5658442;Reactome: R-HSA-5656169;Reactome: R-HSA-2122948;Reactome: R-HSA-5655862;Reactome: R-HSA-6807004;Reactome: R-HSA-174048;Reactome: R-HSA-110320;Reactome: R-HSA-2565942;Reactome: R-HSA-9637628;Reactome: R-HSA-5610780;Reactome: R-HSA-209560;Reactome: R-HSA-5696394;Reactome: R-HSA-8876493;Reactome: R-HSA-8939236;Reactome: R-HSA-1169408;Reactome: R-HSA-9615710;Reactome: R-HSA-2871837;Reactome: R-HSA-5675221;Reactome: R-HSA-1799339;Reactome: R-HSA-2979096;Reactome: R-HSA-1295596;Reactome: R-HSA-6781823;Reactome: R-HSA-2691232;Reactome: R-HSA-9645460;Reactome: R-HSA-69481;Reactome: R-HSA-8856828;Reactome: R-HSA-912631;Reactome: R-HSA-2559585;Reactome: R-HSA-3785653;Reactome: R-HSA-9604323;Reactome: R-HSA-6783310;Reactome: R-HSA-6782210;Reactome: R-HSA-975163;Reactome: R-HSA-5689603;Reactome: R-HSA-937072;Reactome: R-HSA-68949;Reactome: R-HSA-3134975;Reactome: R-HSA-174084;Reactome: R-HSA-110314;Reactome: R-HSA-8948751;Reactome: R-HSA-901032;Reactome: R-HSA-5656121;Reactome: R-HSA-201681;Reactome: R-HSA-5689896;Reactome: R-HSA-69541;Reactome: R-HSA-174113;Reactome: R-HSA-72689;Reactome: R-HSA-182971;Reactome: R-HSA-4641263;Reactome: R-HSA-5696397;Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-5684264;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1236382;Reactome: R-HSA-205043;Reactome: R-HSA-975956;Reactome: R-HSA-5687128;Reactome: R-HSA-174490;Reactome: R-HSA-2408557;Reactome: R-HSA-9033241;Reactome: R-HSA-5357956;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-6782135;Reactome: R-HSA-5654726;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-5654727;Reactome: R-HSA-4641257;Reactome: R-HSA-168638;Reactome: R-HSA-937041;Reactome: R-HSA-5689901;Reactome: R-HSA-8939902;Reactome: R-HSA-9633012;Reactome: R-HSA-175474;Reactome: R-HSA-68827;Reactome: R-HSA-3769402;Reactome: R-HSA-6781827;Reactome: R-HSA-5689877;Reactome: R-HSA-9636383;Reactome: R-HSA-2559582;Reactome: R-HSA-977225;Reactome: R-HSA-975144;Reactome: R-HSA-5693565;Reactome: R-HSA-450321;Reactome: R-HSA-2173788;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-168927;Reactome: R-HSA-9646399;Reactome: R-HSA-5685942;Reactome: R-HSA-2644606;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-936440;Reactome: R-HSA-5693607;Reactome: R-HSA-2672351;Reactome: R-HSA-1358803;Reactome: R-HSA-5696400;Reactome: R-HSA-174154;Reactome: R-HSA-1253288;Reactome: R-HSA-5357905;Reactome: R-HSA-110312;Reactome: R-HSA-5696395;Reactome: R-HSA-9020702;Reactome: R-HSA-937042;Reactome: R-HSA-9013973;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;Reactome: R-HSA-156827;Reactome: R-HSA-187577;Reactome: R-HSA-445989;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-2173795;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-3322077;Reactome: R-HSA-5654732;Reactome: R-HSA-917729;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-9013507;Reactome: R-HSA-162588;Reactome: R-HSA-211733;Reactome: R-HSA-532668;Reactome: R-HSA-8866654;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-8849469;Reactome: R-HSA-5607761;Reactome: R-HSA-8863795;Reactome: R-HSA-5689880;Reactome: R-HSA-917937;Reactome: R-HSA-179409;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-8866652;Reactome: R-HSA-69601;Reactome: R-HSA-5205685;Reactome: R-HSA-5362768;Reactome: R-HSA-9014325;Reactome: R-HSA-5678895;Reactome: R-HSA-937039;Reactome: R-HSA-180534;Reactome: R-HSA-8875360;Reactome: R-HSA-69231;Reactome: R-HSA-180585 "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Negative regulation of FGFR4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Degradation of DVL";"activated TAK1 mediates p38 MAPK activation";"Eukaryotic Translation Termination";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"p75NTR recruits signalling complexes";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of necroptotic cell death";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Chaperone Mediated Autophagy";"Oxidative Stress Induced Senescence";"Hedgehog 'on' state";"Circadian Clock";"Separation of Sister Chromatids";"Viral mRNA Translation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of RAS by GAPs";"Termination of translesion DNA synthesis";"Activated NOTCH1 Transmits Signal to the Nucleus";"Translesion synthesis by POLK";"Negative regulation of MET activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translesion Synthesis by POLH";"Regulation of PLK1 Activity at G2/M Transition";"Modulation by Mtb of host immune system";"Degradation of GLI1 by the proteasome";"NF-kB is activated and signals survival";"DNA Damage Recognition in GG-NER";"InlA-mediated entry of Listeria monocytogenes into host cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ISG15 antiviral mechanism";"Late endosomal microautophagy";"FCERI mediated NF-kB activation";"Negative regulation of MAPK pathway";"SRP-dependent cotranslational protein targeting to membrane";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Spry regulation of FGF signaling";"Formation of TC-NER Pre-Incision Complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Alpha-protein kinase 1 signaling pathway";"G2/M Checkpoints";"Clathrin-mediated endocytosis";"Regulation of signaling by CBL";"Oncogene Induced Senescence";"Myoclonic epilepsy of Lafora";"Negative regulation of NOTCH4 signaling";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"UCH proteinases";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Orc1 removal from chromatin";"Regulation of innate immune responses to cytosolic DNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of PTEN stability and activity";"ER Quality Control Compartment (ERQC)";"Translesion synthesis by POLI";"TCF dependent signaling in response to WNT";"Ovarian tumor domain proteases";"Stabilization of p53";"SCF-beta-TrCP mediated degradation of Emi1";"Formation of a pool of free 40S subunits";"EGFR downregulation";"Regulation of FZD by ubiquitination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"NRIF signals cell death from the nucleus";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"MAPK6/MAPK4 signaling";"Membrane binding and targetting of GAG proteins";"Selenocysteine synthesis";"Peroxisomal protein import";"TNFR1-induced NFkappaB signaling pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Dual incision in TC-NER";"Negative regulation of FGFR1 signaling";"Neddylation";"ABC-family proteins mediated transport";"Negative regulation of FGFR2 signaling";"Degradation of AXIN";"NOD1/2 Signaling Pathway";"IKK complex recruitment mediated by RIP1";"Metalloprotease DUBs";"Regulation of RUNX2 expression and activity";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Assembly Of The HIV Virion";"CDT1 association with the CDC6:ORC:origin complex";"Deactivation of the beta-catenin transactivating complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Josephin domain DUBs";"Prevention of phagosomal-lysosomal fusion";"Senescence-Associated Secretory Phenotype (SASP)";"Amyloid fiber formation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Downregulation of TGF-beta receptor signaling";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"TICAM1, RIP1-mediated IKK complex recruitment";"Aggrephagy";"HDR through Homologous Recombination (HRR)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Negative regulators of DDX58/IFIH1 signaling";"Processing of DNA double-strand break ends";"Stimuli-sensing channels";"Downregulation of ERBB2:ERBB3 signaling";"Dual Incision in GG-NER";"APC/C:Cdc20 mediated degradation of Securin";"Downregulation of ERBB4 signaling";"Regulation of TNFR1 signaling";"Translesion synthesis by REV1";"Formation of Incision Complex in GG-NER";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SCF(Skp2)-mediated degradation of p27/p21";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Glycogen synthesis";"Negative regulation of FGFR3 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Budding and maturation of HIV virion";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"E3 ubiquitin ligases ubiquitinate target proteins";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Dectin-1 mediated noncanonical NF-kB signaling";"Downregulation of ERBB2 signaling";"Ub-specific processing proteases";"Iron uptake and transport";"APC-Cdc20 mediated degradation of Nek2A";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Pink/Parkin Mediated Mitophagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Defective CFTR causes cystic fibrosis";"IRAK1 recruits IKK complex";"Vpu mediated degradation of CD4";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cyclin D associated events in G1";"Vif-mediated degradation of APOBEC3G" EDAN008562-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN015545-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" EDAN001677-PA 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" EDAN000240-PA 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" EDAN006633-PA 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" EDAN015764-PA 56 Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783 "Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome" EDAN017562-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" EDAN007793-PA 6 Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Protein ubiquitination" EDAN019571-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN000381-PA 26 MetaCyc: PWY-6974;MetaCyc: PWY-6953;MetaCyc: PWY-6942;KEGG: 00523+2.7.7.24;MetaCyc: PWY-6808;MetaCyc: PWY-6976;MetaCyc: PWY-7312;MetaCyc: PWY-7413;KEGG: 00521+2.7.7.24;MetaCyc: PWY-7318;KEGG: 00525+4.2.1.46;MetaCyc: PWY-7414;Reactome: R-HSA-5689880;KEGG: 00523+4.2.1.46;MetaCyc: PWY-7440;MetaCyc: PWY-7814;MetaCyc: PWY-7316;KEGG: 00521+4.2.1.46;Reactome: R-HSA-156581;MetaCyc: PWY-7301;MetaCyc: PWY-7104;MetaCyc: PWY-7657;MetaCyc: PWY-6973;MetaCyc: PWY-7315;KEGG: 00525+2.7.7.24;MetaCyc: PWY-7688 "Dtdp-l-olivose biosynthesis";"Dtdp-3-acetamido-alpha-d-fucose biosynthesis";"Dtdp-d-desosamine biosynthesis";"Polyketide sugar unit biosynthesis";"Dtdp-d-forosamine biosynthesis";"Dtdp-l-mycarose biosynthesis";"Dtdp-d-beta-fucofuranose biosynthesis";"Dtdp-6-deoxy-alpha-d-allose biosynthesis";"Streptomycin biosynthesis";"Dtdp-3-acetamido-3,6-dideoxy-alpha-d-glucose biosynthesis";"Acarbose and validamycin biosynthesis";"Dtdp-alpha-d-mycaminose biosynthesis";"Ub-specific processing proteases";"Polyketide sugar unit biosynthesis";"Dtdp-beta-l-4-epi-vancosamine biosynthesis";"Dtdp-l-daunosamine biosynthesis";"Dtdp-n-acetylviosamine biosynthesis";"Streptomycin biosynthesis";"Methylation";"Dtdp-4-o-demethyl-beta-l-noviose biosynthesis";"Dtdp-l-megosamine biosynthesis";"Dtdp-beta-l-digitoxose biosynthesis";"Dtdp-d-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis";"Dtdp-n-acetylthomosamine biosynthesis";"Acarbose and validamycin biosynthesis";"Dtdp-d-ravidosamine and dTDP-4-acetyl-D-ravidosamine biosynthesis" EDAN005744-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN004433-PA 24 Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-392451 "ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"Ca2+ pathway";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma" EDAN019333-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" EDAN011624-PA 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" EDAN008699-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" EDAN006537-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN015165-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" EDAN003404-PA 3 KEGG: 00620+2.3.3.13;MetaCyc: PWY-6871;KEGG: 00290+2.3.3.13 "Pyruvate metabolism";"3-methylbutanol biosynthesis (engineered)";"Valine, leucine and isoleucine biosynthesis" EDAN004447-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" EDAN019262-PA 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" EDAN014860-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN016577-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN008809-PA 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" EDAN018366-PA 13 MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5 "Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Propanoate metabolism" EDAN005045-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN019115-PA 15 MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-6545;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II" EDAN000878-PA 2 Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Pyrimidine salvage";"Pyrimidine catabolism" EDAN003704-PA 5 Reactome: R-HSA-111469;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111463 "SMAC, XIAP-regulated apoptotic response";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs" EDAN013313-PA 1 Reactome: R-HSA-8964539 "Glutamate and glutamine metabolism" EDAN003229-PA 2 Reactome: R-HSA-2187335;Reactome: R-HSA-2453902 "The retinoid cycle in cones (daylight vision)";"The canonical retinoid cycle in rods (twilight vision)" EDAN018788-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN012445-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN010398-PA 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" EDAN019364-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation" EDAN012983-PA 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" EDAN011553-PA 17 MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-7179;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-6611 "Salinosporamide A biosynthesis";"Purine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Guanine and guanosine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Purine catabolism";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage V" EDAN018899-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN003363-PA 4 KEGG: 00300+4.1.1.20;MetaCyc: PWY-2941;MetaCyc: PWY-2942;MetaCyc: PWY-5097 "Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"L-lysine biosynthesis VI" EDAN000033-PA 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" EDAN010242-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006509-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" EDAN009619-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" EDAN008994-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" EDAN008988-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" EDAN018031-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN007276-PA 34 Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-9639288;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Amino acids regulate mTORC1";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation" EDAN013317-PA 5 KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;MetaCyc: PWY-7919 "N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)" EDAN003383-PA 8 MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7854;KEGG: 00630+4.1.3.1;MetaCyc: PWY-6969;MetaCyc: PWY-7118;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7295 "D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"Pyruvate metabolism";"L-arabinose degradation IV" EDAN013909-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN012754-PA 5 Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Intraflagellar transport";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN017865-PA 13 KEGG: 00680+5.4.2.12;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7124;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00010+5.4.2.12;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00260+5.4.2.12;MetaCyc: PWY-7003 "Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Ethylene biosynthesis V (engineered)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"Glycerol degradation to butanol" EDAN006832-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN017328-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN013527-PA 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" EDAN010827-PA 4 KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" EDAN008488-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" EDAN012678-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN002900-PA 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" EDAN004162-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" EDAN009671-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" EDAN007039-PA 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" EDAN018679-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN010611-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN006388-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" EDAN011294-PA 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" EDAN015872-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" EDAN017238-PA 1 MetaCyc: PWY-7379 "Mrna capping II" EDAN003842-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN016607-PA 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" EDAN001479-PA 6 Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" EDAN005264-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN017433-PA 5 KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22 "Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism" EDAN019530-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" EDAN004534-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN013334-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN006957-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN003585-PA 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" EDAN015164-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" EDAN007033-PA 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" EDAN010895-PA 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN016739-PA 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" EDAN007286-PA 6 MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" EDAN012447-PA 5 Reactome: R-HSA-4420097;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-171007 "VEGFA-VEGFR2 Pathway";"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"p38MAPK events" EDAN002113-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" EDAN000477-PA 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" EDAN005219-PA 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" EDAN001609-PA 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" EDAN008133-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN005580-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN018389-PA 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" EDAN006700-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane" EDAN008403-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN006718-PA 4 MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688 "L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism" EDAN010532-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN003188-PA 8 MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1;MetaCyc: PWY-7400;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-5 "Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Canavanine biosynthesis" EDAN012109-PA 7 Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-168333 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery" EDAN009733-PA 9 Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-400253 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock" EDAN016116-PA 12 Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Rho GTPase cycle";"Relaxin signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" EDAN007910-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN007311-PA 7 MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism" EDAN001889-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN006372-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN008842-PA 4 MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7204 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)" EDAN008113-PA 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" EDAN006829-PA 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" EDAN018681-PA 4 MetaCyc: PWY-6281;Reactome: R-HSA-204174;KEGG: 00970+6.1.1.11;Reactome: R-HSA-5362517 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Aminoacyl-tRNA biosynthesis";"Signaling by Retinoic Acid" EDAN001018-PA 3 Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078 "GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" EDAN000053-PA 3 MetaCyc: PWY-5265;MetaCyc: PWY-6471;KEGG: 00550+3.4.16.4 "Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis" EDAN000179-PA 8 KEGG: 00710+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;KEGG: 00030+5.3.1.6;Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-5659996 "Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P" EDAN002568-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" EDAN007342-PA 3 KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN001900-PA 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" EDAN015148-PA 13 MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism" EDAN016766-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN016869-PA 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II" EDAN003162-PA 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" EDAN006927-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" EDAN016420-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN005639-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN005008-PA 1 MetaCyc: PWY-7802 "N-end rule pathway II (prokaryotic)" EDAN017317-PA 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" EDAN011531-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN005404-PA 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" EDAN003167-PA 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" EDAN000026-PA 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" EDAN004644-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN010511-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN012074-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN008882-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN018464-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN015371-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" EDAN016207-PA 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" EDAN001152-PA 14 MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-1482788 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC" EDAN001740-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN000565-PA 2 Reactome: R-HSA-8964539;KEGG: 00240+2.7.4.22 "Glutamate and glutamine metabolism";"Pyrimidine metabolism" EDAN015581-PA 3 MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis" EDAN011641-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway" EDAN012873-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" EDAN006902-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" EDAN008801-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN006729-PA 8 MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-5154;KEGG: 00250+6.3.4.5;KEGG: 00220+6.3.4.5;MetaCyc: PWY-5;MetaCyc: PWY-7400;Reactome: R-HSA-70635 "Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle" EDAN008513-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN005728-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" EDAN008407-PA 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"T cell receptor signaling pathway";"Relaxin signaling pathway" EDAN004946-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN019483-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" EDAN009904-PA 9 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway";"Human papillomavirus infection" EDAN004224-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN009790-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN014995-PA 9 MetaCyc: PWY-7510;MetaCyc: PWY-6682;MetaCyc: PWY-6322;MetaCyc: PWY-5757;MetaCyc: PWY-6839;KEGG: 00998+4.1.1.82;MetaCyc: PWY-8067;KEGG: 00440+4.1.1.82;MetaCyc: PWY-7769 "Rhizocticin A and B biosynthesis";"Dehydrophos biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Fosfomycin biosynthesis";"2-aminoethylphosphonate biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Methylphosphonate biosynthesis";"Phosphonate and phosphinate metabolism";"Phosalacine biosynthesis" EDAN004883-PA 4 Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170 "Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions" EDAN002724-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" EDAN010143-PA 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" EDAN004508-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN001574-PA 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" EDAN000554-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" EDAN016299-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN003402-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" EDAN019184-PA 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" EDAN000034-PA 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" EDAN017153-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN015754-PA 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" EDAN016798-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" EDAN002769-PA 57 Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184 "Degradation of AXIN";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" EDAN010243-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN013405-PA 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" EDAN004165-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN008779-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN011037-PA 4 KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation" EDAN005257-PA 6 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" EDAN014433-PA 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" EDAN011036-PA 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" EDAN003364-PA 4 Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN001017-PA 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" EDAN000488-PA 2 KEGG: 00770+2.7.7.3;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" EDAN010474-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" EDAN019473-PA 4 MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49 "Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway" EDAN001482-PA 2 Reactome: R-HSA-5083628;Reactome: R-HSA-5173105 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation" EDAN000485-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN017307-PA 4 MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" EDAN008867-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN012165-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN005760-PA 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" EDAN005797-PA 2 KEGG: 00240+3.6.1.12;Reactome: R-HSA-499943 "Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" EDAN010865-PA 1 Reactome: R-HSA-186797 "Signaling by PDGF" EDAN008857-PA 14 MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-561 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation" EDAN018481-PA 4 KEGG: 00920+2.5.1.47;KEGG: 00270+2.5.1.47;Reactome: R-HSA-1614603;MetaCyc: PWY-6936 "Sulfur metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Seleno-amino acid biosynthesis (plants)" EDAN004407-PA 6 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination" EDAN005772-PA 9 MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism" EDAN007852-PA 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" EDAN006022-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" EDAN000370-PA 57 Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;MetaCyc: PWY-7893;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-68949 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Protein Pupylation and dePupylation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Regulation of RAS by GAPs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin" EDAN005660-PA 13 MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN005306-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" EDAN005460-PA 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" EDAN002444-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN014522-PA 14 MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-1482788 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC" EDAN018097-PA 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" EDAN005410-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN000275-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN017576-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN013529-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" EDAN007229-PA 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" EDAN003412-PA 12 MetaCyc: PWY-7790;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;KEGG: 00300+1.17.1.8;MetaCyc: PWY-2941;MetaCyc: PWY-5097;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-2942;KEGG: 00261+1.17.1.8 "UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis VI";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I";"UMP biosynthesis III";"L-lysine biosynthesis III";"Monobactam biosynthesis" EDAN008621-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN000806-PA 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" EDAN009614-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN012208-PA 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" EDAN015480-PA 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" EDAN006971-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" EDAN016304-PA 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" EDAN000985-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN018168-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" EDAN011709-PA 4 KEGG: 00910+1.9.6.1;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-5674 "Nitrogen metabolism";"Complex I biogenesis";"Respiratory electron transport";"Nitrate reduction IV (dissimilatory)" EDAN006619-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" EDAN013744-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN009063-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" EDAN002650-PA 4 MetaCyc: PWY-8026;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062 "Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol" EDAN010099-PA 10 Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" EDAN006821-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN010422-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" EDAN005977-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN008347-PA 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" EDAN010205-PA 29 Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167152 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat" EDAN006093-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" EDAN012435-PA 19 Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-432142 "Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"VLDL assembly";"Chylomicron remodeling";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"VLDL clearance";"Platelet sensitization by LDL" EDAN000119-PA 4 Reactome: R-HSA-5362517;Reactome: R-HSA-70895;Reactome: R-HSA-1296072;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"Voltage gated Potassium channels";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN007651-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" EDAN005757-PA 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;MetaCyc: PWY-7176;MetaCyc: PWY-7177;Reactome: R-HSA-499943 "Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates" EDAN005145-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN015846-PA 7 KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11 "Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism" EDAN015594-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN001581-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN010779-PA 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" EDAN005637-PA 12 MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-5856 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)" EDAN005748-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" EDAN005619-PA 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis" EDAN002347-PA 12 Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2894862 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" EDAN003484-PA 3 Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999 "Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" EDAN004409-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN009197-PA 7 Reactome: R-HSA-4086400;Reactome: R-HSA-5368598;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-201681 "PCP/CE pathway";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"WNT mediated activation of DVL";"Degradation of DVL";"TCF dependent signaling in response to WNT" EDAN013956-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN004138-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN000276-PA 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" EDAN012955-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN003283-PA 19 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-5389840;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-5419276;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Mitochondrial translation elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Mitochondrial translation termination";"GTP hydrolysis and joining of the 60S ribosomal subunit" EDAN005414-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN010898-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN014096-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" EDAN009323-PA 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" EDAN004383-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN003988-PA 15 Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends" EDAN000176-PA 3 KEGG: 00860+6.6.1.1;MetaCyc: PWY-5531;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" EDAN016507-PA 4 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation" EDAN003332-PA 13 MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-5132;MetaCyc: PWY-7118;KEGG: 00010+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1 "Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Ethanol oxidation";"Propanoate metabolism";"Methane metabolism";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes" EDAN000272-PA 4 Reactome: R-HSA-1296072;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70895 "Voltage gated Potassium channels";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism" EDAN001747-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" EDAN012083-PA 1 KEGG: 00970+6.1.1.5 "Aminoacyl-tRNA biosynthesis" EDAN013968-PA 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation" EDAN008214-PA 4 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" EDAN006755-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" EDAN003288-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" EDAN011456-PA 4 Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases" EDAN002192-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN004611-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN006194-PA 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" EDAN002963-PA 5 Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756;Reactome: R-HSA-936440;Reactome: R-HSA-6811555 "ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation" EDAN007850-PA 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" EDAN011310-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" EDAN016879-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" EDAN007828-PA 4 MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383 "Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" EDAN001714-PA 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" EDAN007625-PA 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" EDAN001700-PA 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" EDAN006213-PA 12 MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7343 "Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Stachyose degradation";"Starch and sucrose metabolism";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I" EDAN009089-PA 6 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" EDAN012029-PA 18 KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417 "Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Synthesis of PA";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)" EDAN008728-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN006051-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" EDAN000204-PA 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" EDAN009955-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN002580-PA 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" EDAN007590-PA 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism" EDAN018404-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" EDAN014987-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN002525-PA 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" EDAN016039-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN019198-PA 12 MetaCyc: PWY-5133;MetaCyc: PWY-5132;MetaCyc: PWY-7857;MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1 "Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Methane metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism" EDAN000199-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN002665-PA 1 Reactome: R-HSA-8876725 "Protein methylation" EDAN015344-PA 1 Reactome: R-HSA-264876 "Insulin processing" EDAN012829-PA 7 Reactome: R-HSA-1660662;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;MetaCyc: PWY-7841 "Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis" EDAN005643-PA 21 MetaCyc: PWY-7413;KEGG: 00521+2.7.7.24;MetaCyc: PWY-7318;MetaCyc: PWY-6976;MetaCyc: PWY-7312;MetaCyc: PWY-7414;KEGG: 00523+2.7.7.24;MetaCyc: PWY-6974;MetaCyc: PWY-6942;MetaCyc: PWY-6953;MetaCyc: PWY-6808;MetaCyc: PWY-7657;KEGG: 00525+2.7.7.24;MetaCyc: PWY-7688;MetaCyc: PWY-7315;MetaCyc: PWY-6973;MetaCyc: PWY-7814;MetaCyc: PWY-7440;MetaCyc: PWY-7316;MetaCyc: PWY-7301;MetaCyc: PWY-7104 "Dtdp-6-deoxy-alpha-d-allose biosynthesis";"Streptomycin biosynthesis";"Dtdp-3-acetamido-3,6-dideoxy-alpha-d-glucose biosynthesis";"Dtdp-l-mycarose biosynthesis";"Dtdp-d-beta-fucofuranose biosynthesis";"Dtdp-alpha-d-mycaminose biosynthesis";"Polyketide sugar unit biosynthesis";"Dtdp-l-olivose biosynthesis";"Dtdp-d-desosamine biosynthesis";"Dtdp-3-acetamido-alpha-d-fucose biosynthesis";"Dtdp-d-forosamine biosynthesis";"Dtdp-beta-l-digitoxose biosynthesis";"Acarbose and validamycin biosynthesis";"Dtdp-d-ravidosamine and dTDP-4-acetyl-D-ravidosamine biosynthesis";"Dtdp-n-acetylthomosamine biosynthesis";"Dtdp-d-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis";"Dtdp-l-daunosamine biosynthesis";"Dtdp-beta-l-4-epi-vancosamine biosynthesis";"Dtdp-n-acetylviosamine biosynthesis";"Dtdp-4-o-demethyl-beta-l-noviose biosynthesis";"Dtdp-l-megosamine biosynthesis" EDAN003343-PA 6 MetaCyc: PWY-7216;MetaCyc: PWY-5676;MetaCyc: PWY-7948;KEGG: 00630+1.1.1.36;KEGG: 00650+1.1.1.36;MetaCyc: PWY-5741 "(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Acetyl-coa fermentation to butanoate II";"4-oxopentanoate degradation";"Glyoxylate and dicarboxylate metabolism";"Butanoate metabolism";"Ethylmalonyl-coa pathway" EDAN010933-PA 2 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" EDAN003489-PA 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" EDAN019188-PA 4 Reactome: R-HSA-611105;MetaCyc: PWY-5674;KEGG: 00910+1.9.6.1;Reactome: R-HSA-6799198 "Respiratory electron transport";"Nitrate reduction IV (dissimilatory)";"Nitrogen metabolism";"Complex I biogenesis" EDAN016740-PA 4 Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922 "Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" EDAN004399-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" EDAN019569-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN002973-PA 17 KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167246;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167242;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238 "T cell receptor signaling pathway";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Th1 and Th2 cell differentiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation" EDAN003457-PA 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" EDAN010492-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" EDAN005613-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN013974-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN005777-PA 4 Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport" EDAN008543-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" EDAN000118-PA 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN000153-PA 3 KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis" EDAN000499-PA 1 KEGG: 00400+5.3.1.24 "Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN017281-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN008215-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN008916-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN015043-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" EDAN016416-PA 7 Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" EDAN019407-PA 4 KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737 "Arginine and proline metabolism";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis" EDAN019460-PA 3 KEGG: 00260+1.1.1.3;KEGG: 00300+1.1.1.3;KEGG: 00270+1.1.1.3 "Glycine, serine and threonine metabolism";"Lysine biosynthesis";"Cysteine and methionine metabolism" EDAN007181-PA 8 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy" EDAN000335-PA 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" EDAN018398-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" EDAN005322-PA 16 Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-176412 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C" EDAN005805-PA 2 MetaCyc: PWY-7560;KEGG: 00900+1.1.1.267 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" EDAN014511-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN000051-PA 10 Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN013492-PA 11 Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802 "NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3" EDAN001959-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection" EDAN004637-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN002153-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN012961-PA 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" EDAN002857-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN008154-PA 8 Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209 "Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" EDAN010574-PA 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" EDAN003061-PA 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation" EDAN017680-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN004444-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN012599-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN015318-PA 16 Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408 "Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation" EDAN009420-PA 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" EDAN003957-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" EDAN000506-PA 4 KEGG: 00770+6.3.2.5;KEGG: 00770+4.1.1.36+6.3.2.5;Reactome: R-HSA-196783;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" EDAN017947-PA 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" EDAN002798-PA 19 MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00720+2.3.3.8;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;MetaCyc: PWY-5172;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969 "Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" EDAN009589-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" EDAN013810-PA 6 Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" EDAN003137-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" EDAN000082-PA 12 MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537 "TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V" EDAN010184-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN000374-PA 16 MetaCyc: PWY-6519;MetaCyc: PWY-5971;MetaCyc: PWY-6113;MetaCyc: PWY-7663;MetaCyc: PWY-7664;KEGG: 00061+4.2.1.59;MetaCyc: PWY-7858;KEGG: 00540+2.3.1.129;MetaCyc: PWY-6282;Reactome: R-HSA-446205;MetaCyc: PWY-5973;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWYG-321;KEGG: 00780+4.2.1.59;MetaCyc: PWY-8073 "8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Lipopolysaccharide biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Synthesis of GDP-mannose";"Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"";"Biotin metabolism";"Lipid IVA biosynthesis (P. putida)" EDAN000386-PA 2 MetaCyc: PWY-7560;KEGG: 00900+4.6.1.12 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" EDAN007770-PA 5 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism" EDAN017883-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN012760-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN006056-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" EDAN001113-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN006437-PA 44 Reactome: R-HSA-445144;Reactome: R-HSA-982772;Reactome: R-HSA-6802952;Reactome: R-HSA-2559585;Reactome: R-HSA-5673001;Reactome: R-HSA-444257;Reactome: R-HSA-1295596;Reactome: R-HSA-5654733;Reactome: R-HSA-9627069;Reactome: R-HSA-881907;Reactome: R-HSA-879415;Reactome: R-HSA-5668599;Reactome: R-HSA-2559580;Reactome: R-HSA-198753;Reactome: R-HSA-5654726;Reactome: R-HSA-450341;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-5654727;Reactome: R-HSA-112409;Reactome: R-HSA-162658;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-9634638;Reactome: R-HSA-5674499;Reactome: R-HSA-6811558;Reactome: R-HSA-2559582;Reactome: R-HSA-375165;Reactome: R-HSA-3371453;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-8940973;Reactome: R-HSA-9649948;Reactome: R-HSA-8943724;Reactome: R-HSA-5675221;Reactome: R-HSA-9635465;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5663213;Reactome: R-HSA-202670;KEGG: 04150+2.7.11.24;Reactome: R-HSA-74749 "Signal transduction by L1";"Growth hormone receptor signaling";"Signaling by BRAF and RAF fusions";"Oncogene Induced Senescence";"RAF/MAP kinase cascade";"RSK activation";"Spry regulation of FGF signaling";"Negative regulation of FGFR4 signaling";"Regulation of the apoptosome activity";"Gastrin-CREB signalling pathway via PKC and MAPK";"Advanced glycosylation endproduct receptor signaling";"RHO GTPases Activate NADPH Oxidases";"Oxidative Stress Induced Senescence";"ERK/MAPK targets";"Negative regulation of FGFR1 signaling";"Activation of the AP-1 family of transcription factors";"ESR-mediated signaling";"Frs2-mediated activation";"Negative regulation of FGFR2 signaling";"RAF-independent MAPK1/3 activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative feedback regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Senescence-Associated Secretory Phenotype (SASP)";"NCAM signaling for neurite out-growth";"Regulation of HSF1-mediated heat shock response";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"RUNX2 regulates osteoblast differentiation";"Signaling downstream of RAS mutants";"Regulation of PTEN gene transcription";"Negative regulation of MAPK pathway";"Suppression of apoptosis";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RHO GTPases Activate WASPs and WAVEs";"ERKs are inactivated";"mTOR signaling pathway";"Signal attenuation" EDAN014419-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination" EDAN005981-PA 10 Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation" EDAN010347-PA 8 MetaCyc: PWY-7980;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "ATP biosynthesis";"Ion channel transport";"Oxidative phosphorylation";"Photosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" EDAN013253-PA 5 KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4 "Geraniol degradation";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism" EDAN007476-PA 1 Reactome: R-HSA-1296061 "HCN channels" EDAN006660-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN017841-PA 4 KEGG: 00400+4.1.1.48;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" EDAN001074-PA 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression" EDAN012430-PA 4 Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-156581 "tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation" EDAN017102-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN012721-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN002987-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" EDAN004250-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN016279-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" EDAN012203-PA 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" EDAN012725-PA 10 Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-9636383 "Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Prevention of phagosomal-lysosomal fusion" EDAN018915-PA 4 Reactome: R-HSA-1614558;MetaCyc: PWY-5350;MetaCyc: PWY-7927;KEGG: 00920+2.8.1.1 "Degradation of cysteine and homocysteine";"Thiosulfate disproportionation IV (rhodanese)";"Sulfide oxidation IV (mitochondria)";"Sulfur metabolism" EDAN006912-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN004587-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN016554-PA 4 MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2 "(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism" EDAN002272-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN018460-PA 24 Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257 "Cilium Assembly";"Aggrephagy";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion" EDAN006432-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" EDAN003238-PA 5 MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23 "UMP biosynthesis I";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism" EDAN002251-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN001862-PA 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" EDAN000500-PA 4 KEGG: 00400+2.4.2.18;KEGG: 00400+4.1.1.48;Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Pyrimidine salvage";"Pyrimidine catabolism" EDAN019009-PA 3 Reactome: R-HSA-5628897;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Complex I biogenesis";"Respiratory electron transport" EDAN008244-PA 5 Reactome: R-HSA-499943;MetaCyc: PWY-7177;MetaCyc: PWY-7176;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism" EDAN006955-PA 3 Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases" EDAN010565-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN009140-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN001280-PA 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" EDAN003651-PA 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" EDAN005053-PA 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" EDAN012471-PA 52 Reactome: R-HSA-76066;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-73776 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape" EDAN001176-PA 12 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" EDAN008616-PA 3 Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269 "Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis" EDAN008237-PA 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" EDAN003098-PA 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" EDAN005966-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN009258-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN009810-PA 2 Reactome: R-HSA-3322077;Reactome: R-HSA-3785653 "Glycogen synthesis";"Myoclonic epilepsy of Lafora" EDAN016501-PA 10 MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001 "Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" EDAN003265-PA 11 Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-1268020;Reactome: R-HSA-9627069;Reactome: R-HSA-111463 "Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"Mitochondrial protein import";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs" EDAN007385-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN009713-PA 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" EDAN012991-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" EDAN002298-PA 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" EDAN007377-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" EDAN017685-PA 56 Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" EDAN000463-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN008452-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN001916-PA 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" EDAN015811-PA 7 Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" EDAN003060-PA 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" EDAN014519-PA 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" EDAN001529-PA 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" EDAN010473-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN004146-PA 3 KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271 "Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism" EDAN016492-PA 6 Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759 "TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors" EDAN001832-PA 4 Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41 "Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" EDAN005066-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" EDAN017350-PA 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" EDAN019203-PA 6 KEGG: 00220+2.1.3.3;MetaCyc: PWY-4984;MetaCyc: PWY-4981;Reactome: R-HSA-1268020;MetaCyc: PWY-7400;Reactome: R-HSA-70635 "Arginine biosynthesis";"Urea cycle";"L-proline biosynthesis II (from arginine)";"Mitochondrial protein import";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle" EDAN000316-PA 4 KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817 "Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" EDAN010419-PA 1 Reactome: R-HSA-201451 "Signaling by BMP" EDAN006122-PA 3 MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis" EDAN018399-PA 7 MetaCyc: PWY-6922;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN001391-PA 13 Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-419037 "Collagen chain trimerization";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Integrin cell surface interactions";"Signaling by PDGF";"Collagen degradation";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"NCAM1 interactions" EDAN001279-PA 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" EDAN005786-PA 18 KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1 "Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Phenylalanine metabolism";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Tyrosine metabolism" EDAN000709-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN018419-PA 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" EDAN010805-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN010411-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN002469-PA 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" EDAN008608-PA 14 MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I" EDAN003955-PA 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" EDAN015848-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN003895-PA 4 KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" EDAN017682-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN000571-PA 2 KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19 "Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism" EDAN015332-PA 3 Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine" EDAN015329-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN013441-PA 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" EDAN019042-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" EDAN013175-PA 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" EDAN008228-PA 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" EDAN016161-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN012005-PA 3 KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" EDAN001682-PA 14 Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167158 "Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex" EDAN004643-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN019413-PA 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" EDAN013218-PA 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" EDAN000440-PA 6 MetaCyc: PWY-5789;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation" EDAN015351-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" EDAN019503-PA 7 Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex" EDAN000764-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN001509-PA 1 Reactome: R-HSA-916853 "Degradation of GABA" EDAN016194-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" EDAN013490-PA 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" EDAN005634-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN018232-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN006696-PA 12 KEGG: 00130+1.14.99.60;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5870 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" EDAN016082-PA 5 Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-350054 "Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway" EDAN017244-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN014821-PA 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" EDAN009523-PA 14 MetaCyc: PWY-5108;MetaCyc: PWY-5078;KEGG: 00270+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5101;MetaCyc: PWY-5103;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5076 "L-isoleucine biosynthesis V";"L-isoleucine degradation II";"Cysteine and methionine metabolism";"Branched-chain amino acid catabolism";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis III";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-leucine degradation III" EDAN008505-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN006246-PA 7 KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;MetaCyc: PWY-5188 "Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)" EDAN002529-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN018498-PA 10 Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1 "Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Glycolysis";"Glycerol degradation to butanol";"Fructose and mannose metabolism" EDAN006366-PA 7 MetaCyc: PWY-5698;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5;MetaCyc: PWY-7791;MetaCyc: PWY-5686 "Allantoin degradation to ureidoglycolate II (ammonia producing)";"UMP biosynthesis II";"Pyrimidine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism";"UMP biosynthesis III";"UMP biosynthesis I" EDAN008579-PA 5 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols" EDAN015859-PA 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" EDAN016640-PA 4 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines" EDAN003214-PA 13 MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690 "Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)" EDAN012876-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" EDAN004169-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN013551-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN015870-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN007602-PA 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" EDAN013389-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN004770-PA 5 KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" EDAN004053-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN013703-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN017564-PA 18 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7227 "Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis" EDAN018844-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN007169-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN011582-PA 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" EDAN000827-PA 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" EDAN018082-PA 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" EDAN009910-PA 1 Reactome: R-HSA-156581 "Methylation" EDAN016752-PA 2 Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Glycolysis";"Gluconeogenesis" EDAN007243-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN019319-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN011525-PA 13 MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I" EDAN009269-PA 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" EDAN018248-PA 4 KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817 "Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" EDAN007211-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" EDAN019187-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN007864-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN014019-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN000196-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN014416-PA 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" EDAN013192-PA 52 Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702 "Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling" EDAN015943-PA 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" EDAN014578-PA 5 MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" EDAN011056-PA 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" EDAN016748-PA 7 Reactome: R-HSA-156581;Reactome: R-HSA-3359469;Reactome: R-HSA-3359467;Reactome: R-HSA-196741;Reactome: R-HSA-1614635;MetaCyc: PWY-6614;KEGG: 00790+2.5.1.15 "Methylation";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Sulfur amino acid metabolism";"Tetrahydrofolate biosynthesis";"Folate biosynthesis" EDAN016244-PA 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" EDAN004739-PA 3 MetaCyc: PWY-7511;Reactome: R-HSA-532668;Reactome: R-HSA-901032 "Protein ubiquitination";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ER Quality Control Compartment (ERQC)" EDAN016629-PA 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes" EDAN003468-PA 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" EDAN006157-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN007339-PA 5 Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825 "Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis" EDAN014690-PA 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" EDAN006856-PA 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" EDAN013862-PA 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" EDAN005209-PA 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" EDAN000114-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN009809-PA 4 KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis" EDAN000459-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN000614-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-5389840;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-5419276;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-5368286 "SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Mitochondrial translation termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Mitochondrial translation initiation" EDAN010402-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN000042-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN006756-PA 2 KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" EDAN018055-PA 13 MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545 "Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN017676-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" EDAN001041-PA 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" EDAN018749-PA 1 KEGG: 00970+6.1.1.5 "Aminoacyl-tRNA biosynthesis" EDAN014939-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN016148-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN004799-PA 19 MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288 "Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)" EDAN013421-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" EDAN015031-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN011733-PA 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" EDAN016709-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN000549-PA 7 MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" EDAN001690-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" EDAN007049-PA 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" EDAN013667-PA 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" EDAN011209-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006874-PA 6 MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation" EDAN011361-PA 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" EDAN006394-PA 14 Reactome: R-HSA-1474228;Reactome: R-HSA-6798695;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-977225 "Degradation of the extracellular matrix";"Neutrophil degranulation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Amyloid fiber formation" EDAN000180-PA 14 MetaCyc: PWY-7385;MetaCyc: PWY-5661;KEGG: 00052+2.7.1.2;MetaCyc: PWY-2723;KEGG: 00520+2.7.1.2;MetaCyc: PWY-621;MetaCyc: PWY-5514;KEGG: 00524+2.7.1.2;KEGG: 00010+2.7.1.2;MetaCyc: PWY-7238;MetaCyc: PWY-2722;KEGG: 00500+2.7.1.2;KEGG: 00521+2.7.1.2;MetaCyc: PWY-5941 "1,3-propanediol biosynthesis (engineered)";"GDP-glucose biosynthesis";"Galactose metabolism";"Trehalose degradation V";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation III (sucrose invertase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis II";"Trehalose degradation IV";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycogen degradation II" EDAN010004-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" EDAN006790-PA 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events" EDAN006792-PA 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events" EDAN003679-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN009392-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN007603-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN008119-PA 4 Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" EDAN015881-PA 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" EDAN009505-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN008869-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" EDAN015659-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN007130-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" EDAN017239-PA 1 MetaCyc: PWY-7379 "Mrna capping II" EDAN001278-PA 9 Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-5649702;Reactome: R-HSA-110357;Reactome: R-HSA-9656255;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-9656256 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Defective OGG1 Localization";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Binding";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Processing" EDAN005663-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN017561-PA 3 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2 "ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis" EDAN010796-PA 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" EDAN014264-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN010675-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" EDAN000068-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN015999-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" EDAN013888-PA 12 Reactome: R-HSA-2894862;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-982772;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-5362798;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TNF signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Growth hormone receptor signaling";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Signaling by EGFR" EDAN015322-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN006106-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" EDAN005659-PA 17 KEGG: 00620+2.3.1.8;KEGG: 00640+2.7.2.1;MetaCyc: PWY-5482;MetaCyc: PWY-1281;KEGG: 00720+2.3.1.8;MetaCyc: PWY-5497;MetaCyc: PWY-8015;KEGG: 00680+2.3.1.8;MetaCyc: PWY-5485;KEGG: 00430+2.7.2.1;KEGG: 00640+2.3.1.8;KEGG: 00430+2.3.1.8;KEGG: 00680+2.7.2.1;KEGG: 00620+2.7.2.1;MetaCyc: PWY-6637;MetaCyc: PWY-8086;KEGG: 00720+2.7.2.1 "Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to acetate II";"Sulfoacetaldehyde degradation I";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Glycine degradation (Stickland reaction)";"Methane metabolism";"Pyruvate fermentation to acetate IV";"Taurine and hypotaurine metabolism";"Propanoate metabolism";"Taurine and hypotaurine metabolism";"Methane metabolism";"Pyruvate metabolism";"Sulfolactate degradation II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes" EDAN012146-PA 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" EDAN000562-PA 3 MetaCyc: PWY-5154;KEGG: 00220+1.2.1.38;MetaCyc: PWY-7400 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)" EDAN013679-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" EDAN013659-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN001494-PA 9 MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series" EDAN012706-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" EDAN013079-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" EDAN006854-PA 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" EDAN000550-PA 5 MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism" EDAN001973-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN000171-PA 11 KEGG: 00061+1.3.1.9;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWYG-321;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWY-6113;MetaCyc: PWY-7664;MetaCyc: PWY-7858 "Fatty acid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II" EDAN014366-PA 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" EDAN009528-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" EDAN014531-PA 6 KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807 "Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)" EDAN014006-PA 4 Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" EDAN002480-PA 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" EDAN014076-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN003109-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN005542-PA 8 Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-8941284;Reactome: R-HSA-5362798 "Hedgehog ligand biogenesis";"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Activation of SMO";"RUNX2 regulates chondrocyte maturation";"Release of Hh-Np from the secreting cell" EDAN014614-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" EDAN013209-PA 6 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" EDAN003512-PA 12 KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4 "Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism" EDAN019196-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN004842-PA 6 MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;Reactome: R-HSA-196807 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism" EDAN004590-PA 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" EDAN000090-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" EDAN013669-PA 14 MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7587 "CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)" EDAN002053-PA 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" EDAN005625-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN005783-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" EDAN018826-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN014142-PA 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" EDAN004859-PA 14 Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426486 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis" EDAN012936-PA 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" EDAN005895-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN011265-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" EDAN011073-PA 13 MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates" EDAN004627-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN018803-PA 16 MetaCyc: PWY-5971;MetaCyc: PWY-6113;MetaCyc: PWY-7663;MetaCyc: PWY-7664;MetaCyc: PWY-7858;MetaCyc: PWY-6519;KEGG: 00780+1.1.1.100;KEGG: 00061+2.3.1.180;MetaCyc: PWY-5367;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-5989;MetaCyc: PWY-6282;MetaCyc: PWY-4381;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Biotin metabolism";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis" EDAN017586-PA 1 Reactome: R-HSA-373760 "L1CAM interactions" EDAN018759-PA 18 KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913 "Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Arginine and proline metabolism";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)" EDAN005177-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN007045-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN017176-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN019455-PA 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" EDAN017982-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN010072-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" EDAN000274-PA 6 KEGG: 00550+2.4.1.129+3.4.16.4;MetaCyc: PWY-6470;MetaCyc: PWY-6385;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.129;MetaCyc: PWY-5265 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)" EDAN003899-PA 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1" EDAN000959-PA 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" EDAN013614-PA 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" EDAN000582-PA 10 MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)" EDAN006292-PA 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" EDAN005482-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" EDAN001604-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" EDAN000434-PA 4 Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829 "ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" EDAN000397-PA 19 Reactome: R-HSA-5368286;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-5419276;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Mitochondrial translation termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation elongation" EDAN003473-PA 3 MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3 "Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism" EDAN006220-PA 14 MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" EDAN008465-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" EDAN003360-PA 4 KEGG: 00400+4.2.3.4;KEGG: 00400+2.7.1.71;MetaCyc: PWY-6163;MetaCyc: PWY-6164 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Chorismate biosynthesis from 3-dehydroquinate";"3-dehydroquinate biosynthesis I" EDAN009242-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN006123-PA 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833 "ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)" EDAN011731-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN003358-PA 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" EDAN006045-PA 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" EDAN011342-PA 5 MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013 "CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" EDAN009597-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN010210-PA 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" EDAN013581-PA 13 Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-2243919;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-216083 "Collagen degradation";"ECM proteoglycans";"NCAM1 interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Laminin interactions";"Crosslinking of collagen fibrils";"Collagen chain trimerization";"Signaling by PDGF";"Integrin cell surface interactions" EDAN012004-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN011783-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN005304-PA 3 Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220 "Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins" EDAN012482-PA 12 KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6122 "Purine metabolism";"Biotin transport and metabolism";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" EDAN002395-PA 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" EDAN011703-PA 1 Reactome: R-HSA-71262 "Carnitine synthesis" EDAN014683-PA 1 Reactome: R-HSA-8949613 "Cristae formation" EDAN011831-PA 4 Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187 "Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress" EDAN009002-PA 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" EDAN011577-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN018361-PA 4 Reactome: R-HSA-71403;MetaCyc: PWY-7396;KEGG: 00290+1.1.1.85;KEGG: 00660+1.1.1.85 "Citric acid cycle (TCA cycle)";"Butanol and isobutanol biosynthesis (engineered)";"Valine, leucine and isoleucine biosynthesis";"C5-Branched dibasic acid metabolism" EDAN000603-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" EDAN003222-PA 2 MetaCyc: PWY-6700;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" EDAN001969-PA 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" EDAN014902-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN001262-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN002567-PA 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" EDAN010928-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN005307-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" EDAN014365-PA 5 Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" EDAN000584-PA 10 MetaCyc: PWY-8067;MetaCyc: PWY-6839;KEGG: 00998+5.4.2.9;MetaCyc: PWY-7769;KEGG: 00440+5.4.2.9;MetaCyc: PWY-7419;MetaCyc: PWY-6682;MetaCyc: PWY-7510;MetaCyc: PWY-6322;MetaCyc: PWY-5757 "Methylphosphonate biosynthesis";"2-aminoethylphosphonate biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"Phosalacine biosynthesis";"Phosphonate and phosphinate metabolism";"FR-900098 and FR-33289 antibiotics biosynthesis";"Dehydrophos biosynthesis";"Rhizocticin A and B biosynthesis";"Phosphinothricin tripeptide biosynthesis";"Fosfomycin biosynthesis" EDAN012075-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN016049-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN000399-PA 4 KEGG: 00520+2.7.7.33;MetaCyc: PWY-5940;KEGG: 00500+2.7.7.33;MetaCyc: PWY-5833 "Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"CDP-4-dehydro-3,6-dideoxy-D-glucose biosynthesis" EDAN008383-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN010322-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN008443-PA 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism" EDAN017664-PA 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" EDAN002257-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN012110-PA 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" EDAN019122-PA 17 MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969 "Reductive TCA cycle II";"Methane metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" EDAN007504-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN002253-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN005644-PA 8 MetaCyc: PWY-7328;MetaCyc: PWY-7344;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)" EDAN012196-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" EDAN006765-PA 11 Reactome: R-HSA-1660517;Reactome: R-HSA-168138;Reactome: R-HSA-109704;KEGG: 00562+2.7.1.137;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1632852;MetaCyc: PWY-6352;Reactome: R-HSA-5668599 "Synthesis of PIPs at the late endosome membrane";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Macroautophagy";"3-phosphoinositide biosynthesis";"RHO GTPases Activate NADPH Oxidases" EDAN018375-PA 13 MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-6545 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN008423-PA 3 Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206291 "HS-GAG degradation";"Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C" EDAN003370-PA 5 MetaCyc: PWY-6386;MetaCyc: PWY-7953;MetaCyc: PWY-6387;KEGG: 00550+6.3.2.4;KEGG: 00473+6.3.2.4 "UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Peptidoglycan biosynthesis";"D-Alanine metabolism" EDAN013816-PA 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" EDAN010793-PA 8 MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695 "Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine metabolism";"Neutrophil degranulation" EDAN017826-PA 19 Reactome: R-HSA-9010553;Reactome: R-HSA-5419276;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-5368286;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-5389840;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Mitochondrial translation termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Mitochondrial translation initiation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Mitochondrial translation elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" EDAN001220-PA 4 Reactome: R-HSA-167160;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"mRNA Capping" EDAN007186-PA 6 Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;MetaCyc: PWY-6908 "Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)" EDAN019019-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN003204-PA 6 KEGG: 00960+2.6.1.9;KEGG: 00340+2.6.1.9;KEGG: 00360+2.6.1.9;KEGG: 00400+2.6.1.9;KEGG: 00401+2.6.1.9;KEGG: 00350+2.6.1.9 "Tropane, piperidine and pyridine alkaloid biosynthesis";"Histidine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism" EDAN019258-PA 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" EDAN016366-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN012066-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" EDAN017234-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN012363-PA 7 MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism" EDAN000612-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN006091-PA 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" EDAN005917-PA 2 KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" EDAN002312-PA 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" EDAN011529-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN007303-PA 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" EDAN008960-PA 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" EDAN019277-PA 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" EDAN009488-PA 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" EDAN019448-PA 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" EDAN006604-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" EDAN016345-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN000131-PA 6 MetaCyc: PWY-5097;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-2942 "L-lysine biosynthesis VI";"Dipicolinate biosynthesis";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III" EDAN004722-PA 11 Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" EDAN007426-PA 3 Reactome: R-HSA-111471;Reactome: R-HSA-9645722;Reactome: R-HSA-140837 "Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation" EDAN001166-PA 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" EDAN009825-PA 1 Reactome: R-HSA-71064 "Lysine catabolism" EDAN002742-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN008354-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN012376-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN016481-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN000669-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" EDAN005633-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN002452-PA 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684 "Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state" EDAN003300-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" EDAN009412-PA 8 Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690 "Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events" EDAN017815-PA 3 Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2 "Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway" EDAN012843-PA 1 Reactome: R-HSA-1221632 "Meiotic synapsis" EDAN004502-PA 8 MetaCyc: PWY-7980;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "ATP biosynthesis";"Ion channel transport";"Oxidative phosphorylation";"Photosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" EDAN006518-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" EDAN016930-PA 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" EDAN019058-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN002315-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" EDAN008529-PA 14 Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5685942 "Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)" EDAN000905-PA 4 MetaCyc: PWY-7849;MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97 "Urate conversion to allantoin III";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism" EDAN013613-PA 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" EDAN012473-PA 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" EDAN018236-PA 20 Reactome: R-HSA-72706;Reactome: R-HSA-5419276;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-5368286;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-114608;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-5389840;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial translation termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Mitochondrial translation initiation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Platelet degranulation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" EDAN010987-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN019207-PA 13 MetaCyc: PWY-7227;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545 "Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN010300-PA 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" EDAN014014-PA 2 Reactome: R-HSA-177135;Reactome: R-HSA-177128 "Conjugation of benzoate with glycine";"Conjugation of salicylate with glycine" EDAN008432-PA 1 Reactome: R-HSA-73943 "Reversal of alkylation damage by DNA dioxygenases" EDAN004595-PA 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs" EDAN001755-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN003493-PA 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" EDAN005756-PA 3 KEGG: 00540+2.5.1.55;MetaCyc: PWY-1269;MetaCyc: PWY-7674 "Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis" EDAN016296-PA 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" EDAN004182-PA 9 Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" EDAN000344-PA 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" EDAN015871-PA 4 MetaCyc: PWY-5028;Reactome: R-HSA-70921;MetaCyc: PWY-5030;KEGG: 00340+4.2.1.49 "L-histidine degradation II";"Histidine catabolism";"L-histidine degradation III";"Histidine metabolism" EDAN011581-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN012166-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN012954-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN000627-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" EDAN006377-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" EDAN012140-PA 2 Reactome: R-HSA-901032;MetaCyc: PWY-7511 "ER Quality Control Compartment (ERQC)";"Protein ubiquitination" EDAN001125-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN006634-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN008906-PA 56 Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Regulation of RAS by GAPs" EDAN011573-PA 8 MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism" EDAN003633-PA 10 Reactome: R-HSA-9027276;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153 "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"mTOR signaling pathway";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" EDAN000046-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN000646-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN013812-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN008083-PA 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" EDAN004628-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN001769-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN017834-PA 16 Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" EDAN008602-PA 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" EDAN018938-PA 9 MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902 "Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)" EDAN001161-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN007509-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" EDAN006730-PA 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" EDAN011806-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" EDAN012774-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN000197-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN003091-PA 16 Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-2467813 "APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids" EDAN003846-PA 5 MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-7817 "Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)" EDAN007170-PA 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" EDAN001971-PA 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" EDAN013718-PA 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" EDAN012679-PA 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" EDAN003994-PA 6 MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" EDAN000217-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN017545-PA 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-3232118;Reactome: R-HSA-5693565;Reactome: R-HSA-69473 "Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"SUMOylation of transcription factors";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint" EDAN016295-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" EDAN013863-PA 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" EDAN007645-PA 33 Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-69656;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-112382 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex" EDAN008439-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN019166-PA 2 KEGG: 00260+4.2.1.20;KEGG: 00400+4.2.1.20 "Glycine, serine and threonine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN005519-PA 2 KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6 "Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism" EDAN000115-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN010468-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN012080-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN005475-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN009294-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" EDAN007404-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN005278-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN008049-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN004914-PA 6 KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530 "Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Sorbitol biosynthesis II" EDAN013059-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN001418-PA 30 Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-2564830;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167160 "Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" EDAN012548-PA 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" EDAN000402-PA 5 MetaCyc: PWY-6578;MetaCyc: PWY-6519;MetaCyc: PWY-7147;KEGG: 00780+2.3.1.47;Reactome: R-HSA-173599 "8-amino-7-oxononanoate biosynthesis III";"8-amino-7-oxononanoate biosynthesis I";"8-amino-7-oxononanoate biosynthesis II";"Biotin metabolism";"Formation of the active cofactor, UDP-glucuronate" EDAN015637-PA 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" EDAN009988-PA 1 Reactome: R-HSA-400253 "Circadian Clock" EDAN000373-PA 10 MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527 "Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Stachyose degradation" EDAN019482-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN015071-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation" EDAN007246-PA 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" EDAN011718-PA 6 MetaCyc: PWY-622;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch biosynthesis";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" EDAN000016-PA 10 MetaCyc: PWY-5497;KEGG: 00720+2.7.2.1;MetaCyc: PWY-8086;MetaCyc: PWY-8015;KEGG: 00640+2.7.2.1;MetaCyc: PWY-5482;MetaCyc: PWY-5485;KEGG: 00620+2.7.2.1;KEGG: 00680+2.7.2.1;KEGG: 00430+2.7.2.1 "Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glycine degradation (Stickland reaction)";"Propanoate metabolism";"Pyruvate fermentation to acetate II";"Pyruvate fermentation to acetate IV";"Pyruvate metabolism";"Methane metabolism";"Taurine and hypotaurine metabolism" EDAN005690-PA 15 MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-6886;KEGG: 00260+5.4.2.12;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7124;KEGG: 00680+5.4.2.12;KEGG: 00010+5.4.2.12;MetaCyc: PWY-5723;MetaCyc: PWY-1042;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN006827-PA 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" EDAN012837-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN016229-PA 6 KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;Reactome: R-HSA-389661;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892 "Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Glyoxylate metabolism and glycine degradation";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)" EDAN016278-PA 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" EDAN005900-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" EDAN004731-PA 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" EDAN008573-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" EDAN014906-PA 1 Reactome: R-HSA-6804115 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" EDAN001141-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" EDAN007771-PA 5 KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism" EDAN013589-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN018242-PA 7 MetaCyc: PWY-7560;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 00900+1.1.1.267;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "Methylerythritol phosphate pathway II";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Terpenoid backbone biosynthesis";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" EDAN005737-PA 18 Reactome: R-HSA-70895;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00380+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00640+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00020+1.8.1.4;KEGG: 00010+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-71064;MetaCyc: PWY-5046;Reactome: R-HSA-389661;MetaCyc: PWY-5084;Reactome: R-HSA-204174;KEGG: 00310+1.8.1.4 "Branched-chain amino acid catabolism";"Glycine, serine and threonine metabolism";"Pyruvate metabolism";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Lysine catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine degradation" EDAN007848-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN017306-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN006629-PA 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" EDAN017882-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN003786-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" EDAN005725-PA 2 Reactome: R-HSA-912446;Reactome: R-HSA-5368286 "Meiotic recombination";"Mitochondrial translation initiation" EDAN003439-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation" EDAN014491-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN000311-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN009094-PA 1 Reactome: R-HSA-211981 "Xenobiotics" EDAN019344-PA 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage" EDAN010508-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN010517-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN006128-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" EDAN014540-PA 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" EDAN006304-PA 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" EDAN004625-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN009917-PA 3 Reactome: R-HSA-1566948;Reactome: R-HSA-2129379;Reactome: R-HSA-1474228 "Elastic fibre formation";"Molecules associated with elastic fibres";"Degradation of the extracellular matrix" EDAN009044-PA 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" EDAN005898-PA 56 Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154 "Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin" EDAN011196-PA 4 Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847 "UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones" EDAN015392-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN016363-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" EDAN009410-PA 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" EDAN003540-PA 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" EDAN013946-PA 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" EDAN019031-PA 12 MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913 "TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)" EDAN005255-PA 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" EDAN017657-PA 9 Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-975634 "Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport" EDAN000953-PA 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" EDAN019211-PA 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" EDAN015781-PA 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" EDAN007508-PA 3 Reactome: R-HSA-373080;Reactome: R-HSA-3238698;Reactome: R-HSA-4086400 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking";"PCP/CE pathway" EDAN011615-PA 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" EDAN011272-PA 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" EDAN015471-PA 14 Reactome: R-HSA-380259;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Loss of Nlp from mitotic centrosomes";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" EDAN019536-PA 10 MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11 "Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Methane metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism" EDAN000058-PA 3 Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669 "Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" EDAN013797-PA 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" EDAN013104-PA 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" EDAN005811-PA 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" EDAN003194-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN016734-PA 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" EDAN005860-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN016109-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN018934-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation" EDAN005272-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" EDAN000270-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" EDAN004230-PA 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" EDAN006510-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" EDAN007134-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" EDAN004228-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN004025-PA 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" EDAN013464-PA 7 MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25 "Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis" EDAN004035-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN012314-PA 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" EDAN000854-PA 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" EDAN004101-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" EDAN005817-PA 4 Reactome: R-HSA-71403;MetaCyc: PWY-7396;KEGG: 00290+1.1.1.85;KEGG: 00660+1.1.1.85 "Citric acid cycle (TCA cycle)";"Butanol and isobutanol biosynthesis (engineered)";"Valine, leucine and isoleucine biosynthesis";"C5-Branched dibasic acid metabolism" EDAN003763-PA 5 Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)" EDAN017177-PA 52 Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-75953 "Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation" EDAN018181-PA 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" EDAN010108-PA 12 Reactome: R-HSA-73780;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" EDAN004898-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN010488-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN016127-PA 3 KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" EDAN005413-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN019218-PA 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" EDAN016078-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN017313-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" EDAN014115-PA 6 Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination" EDAN004558-PA 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" EDAN012968-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN007532-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" EDAN004249-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN001148-PA 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" EDAN018185-PA 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" EDAN006117-PA 5 Reactome: R-HSA-201681;Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751 "TCF dependent signaling in response to WNT";"Degradation of AXIN";"Protein ubiquitination";"Ub-specific processing proteases";"Regulation of PTEN stability and activity" EDAN003397-PA 2 KEGG: 00770+2.7.7.3;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" EDAN005985-PA 1 Reactome: R-HSA-525793 "Myogenesis" EDAN001408-PA 13 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-186797;Reactome: R-HSA-216083 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"NCAM1 interactions";"Anchoring fibril formation";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Signaling by PDGF";"Integrin cell surface interactions" EDAN004231-PA 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" EDAN000208-PA 1 Reactome: R-HSA-70635 "Urea cycle" EDAN016909-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" EDAN000987-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN010137-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" EDAN017639-PA 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" EDAN006101-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" EDAN018452-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN019121-PA 17 KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-7383;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37 "Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Methane metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism" EDAN001988-PA 7 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" EDAN009888-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN014104-PA 26 Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-2132295 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Kinesins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Aggrephagy";"Cilium Assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation" EDAN019091-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN008093-PA 3 Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" EDAN007158-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN016192-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" EDAN018254-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN009278-PA 6 MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3 "Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" EDAN003781-PA 3 Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517 "Ca2+ pathway";"cGMP effects";"Rap1 signalling" EDAN000512-PA 13 MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-8086;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913 "TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)" EDAN012305-PA 11 Reactome: R-HSA-8866654;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "E3 ubiquitin ligases ubiquitinate target proteins";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"IRF3-mediated induction of type I IFN";"PI3K-Akt signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Human cytomegalovirus infection";"Thermogenesis" EDAN007458-PA 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" EDAN012808-PA 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" EDAN004575-PA 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" EDAN000429-PA 1 Reactome: R-HSA-6783984 "Glycine degradation" EDAN019570-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN008071-PA 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" EDAN015213-PA 1 Reactome: R-HSA-8964572 "Lipid particle organization" EDAN002460-PA 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" EDAN010420-PA 1 Reactome: R-HSA-201451 "Signaling by BMP" EDAN008146-PA 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" EDAN018910-PA 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" EDAN003107-PA 27 Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" EDAN014546-PA 1 Reactome: R-HSA-977347 "Serine biosynthesis" EDAN019391-PA 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" EDAN003415-PA 4 Reactome: R-HSA-8949613;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505 "Cristae formation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" EDAN003500-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" EDAN003099-PA 8 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288 "Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1" EDAN019204-PA 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism" EDAN008045-PA 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" EDAN002563-PA 14 Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167246 "Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript" EDAN000418-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN000186-PA 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" EDAN011293-PA 19 Reactome: R-HSA-380320;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226 "Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I" EDAN004060-PA 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" EDAN016998-PA 20 MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7338 "10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" EDAN015022-PA 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" EDAN018013-PA 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" EDAN019465-PA 19 MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-7337 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)" EDAN013224-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN010829-PA 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" EDAN014356-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN018980-PA 5 KEGG: 00860+2.5.1.61;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Porphyrin and chlorophyll metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" EDAN019459-PA 6 KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;MetaCyc: PWY-6362 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" EDAN007601-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN012025-PA 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" EDAN015276-PA 5 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription" EDAN007106-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN004857-PA 14 Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398 "Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway" EDAN014294-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN009849-PA 57 Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-532668;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-174113 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Degradation of AXIN";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1" EDAN014595-PA 7 Reactome: R-HSA-390471;Reactome: R-HSA-8950505;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922 "Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium" EDAN016021-PA 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" EDAN018794-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" EDAN014221-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN000360-PA 4 KEGG: 00983+2.3.1.5;KEGG: 00232+2.3.1.5;KEGG: 00633+2.3.1.5;Reactome: R-HSA-156582 "Drug metabolism - other enzymes";"Caffeine metabolism";"Nitrotoluene degradation";"Acetylation" EDAN010111-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" EDAN000245-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN000658-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN003276-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN010598-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN004688-PA 57 Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8948751 "Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"UCH proteinases";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity" EDAN002950-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" EDAN019063-PA 5 Reactome: R-HSA-70895;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Branched-chain amino acid catabolism";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN003299-PA 6 KEGG: 00240+3.6.1.23;MetaCyc: PWY-7851;KEGG: 00770+4.1.1.36+6.3.2.5;Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Drug metabolism - other enzymes" EDAN013147-PA 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" EDAN017180-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN001894-PA 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" EDAN008872-PA 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" EDAN012561-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN005555-PA 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" EDAN000482-PA 3 Reactome: R-HSA-204174;Reactome: R-HSA-70895;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid" EDAN012361-PA 4 MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation" EDAN011683-PA 4 KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism" EDAN013034-PA 13 MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN019425-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN006169-PA 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" EDAN007056-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN012242-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN001633-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" EDAN019609-PA 5 Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413 "DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression" EDAN011609-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN012795-PA 57 Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69601 "Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" EDAN010286-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN003641-PA 22 Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5467340 "Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex" EDAN002630-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN003016-PA 5 Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661 "Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation" EDAN014685-PA 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" EDAN000061-PA 5 KEGG: 00520+2.5.1.7;KEGG: 00550+2.5.1.7;MetaCyc: PWY-6386;MetaCyc: PWY-6387;MetaCyc: PWY-7953 "Amino sugar and nucleotide sugar metabolism";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)" EDAN003113-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN005636-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN001314-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN008157-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN001901-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN010849-PA 24 Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833 "Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Recycling pathway of L1";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"Aggrephagy";"Cilium Assembly" EDAN003163-PA 2 Reactome: R-HSA-1296072;Reactome: R-HSA-936837 "Voltage gated Potassium channels";"Ion transport by P-type ATPases" EDAN007631-PA 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" EDAN003926-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance" EDAN002492-PA 6 Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900 "Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" EDAN002709-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" EDAN002610-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN001575-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN019272-PA 11 Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-1268020;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-111464 "Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Mitochondrial protein import";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" EDAN016867-PA 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" EDAN007413-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN017261-PA 9 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation" EDAN000515-PA 8 MetaCyc: PWY-7573;MetaCyc: PWY-5740;Reactome: R-HSA-6787639;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738 "GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis" EDAN004373-PA 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" EDAN014232-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" EDAN006712-PA 5 KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III" EDAN007041-PA 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" EDAN008457-PA 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" EDAN007262-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN001133-PA 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" EDAN003865-PA 16 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" EDAN006301-PA 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" EDAN009054-PA 31 MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-7664;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7858;Reactome: R-HSA-75105;MetaCyc: PWY-5971;MetaCyc: PWY-7663;MetaCyc: PWY-8049;MetaCyc: PWY-6113;MetaCyc: PWY-5366;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-4381;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-5989;MetaCyc: PWYG-321 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Pederin biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Stearate biosynthesis II (bacteria and plants)";"" EDAN001672-PA 7 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation" EDAN011648-PA 5 MetaCyc: PWY-7674;MetaCyc: PWY-1269;KEGG: 00400+2.5.1.54;KEGG: 00540+2.5.1.55;MetaCyc: PWY-6164 "CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Lipopolysaccharide biosynthesis";"3-dehydroquinate biosynthesis I" EDAN000025-PA 3 Reactome: R-HSA-3371599;Reactome: R-HSA-70263;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Biotin transport and metabolism" EDAN013912-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" EDAN001684-PA 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7;Reactome: R-HSA-5368286 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation" EDAN013905-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" EDAN015439-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN012772-PA 56 Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling" EDAN014150-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" EDAN000055-PA 16 MetaCyc: PWY-7153;MetaCyc: PWY-6562;KEGG: 00261+1.2.1.11;KEGG: 00260+1.2.1.11;MetaCyc: PWY-7400;MetaCyc: PWY-7977;KEGG: 00300+1.2.1.11;KEGG: 00220+1.2.1.38;MetaCyc: PWY-2942;MetaCyc: PWY-5154;KEGG: 00270+1.2.1.11;MetaCyc: PWY-2941;MetaCyc: PWY-5097;MetaCyc: PWY-6559;MetaCyc: PWY-8088;MetaCyc: PWY-6160 "Grixazone biosynthesis";"Norspermidine biosynthesis";"Monobactam biosynthesis";"Glycine, serine and threonine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-methionine biosynthesis IV (archaea)";"Lysine biosynthesis";"Arginine biosynthesis";"L-lysine biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Cysteine and methionine metabolism";"L-lysine biosynthesis II";"L-lysine biosynthesis VI";"Spermidine biosynthesis II";"Dipicolinate biosynthesis";"3-dehydroquinate biosynthesis II (archaea)" EDAN010797-PA 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" EDAN001201-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN019243-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" EDAN015772-PA 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" EDAN017784-PA 1 Reactome: R-HSA-3295583 "TRP channels" EDAN009009-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6783310 "Neutrophil degranulation";"Fanconi Anemia Pathway" EDAN002766-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN016529-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN017711-PA 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis" EDAN003280-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN009067-PA 1 Reactome: R-HSA-420029 "Tight junction interactions" EDAN003352-PA 5 KEGG: 00230+2.4.2.15;KEGG: 00983+2.4.2.4+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2;MetaCyc: PWY-7181 "Purine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation" EDAN010475-PA 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" EDAN012820-PA 4 Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72 "Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis" EDAN018117-PA 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" EDAN006781-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" EDAN006906-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" EDAN003221-PA 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" EDAN009072-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" EDAN000377-PA 3 KEGG: 00520+2.5.1.97;Reactome: R-HSA-4085001;MetaCyc: PWY-6143 "Amino sugar and nucleotide sugar metabolism";"Sialic acid metabolism";"CMP-pseudaminate biosynthesis" EDAN013374-PA 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" EDAN001787-PA 7 Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288 "mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1" EDAN013864-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN005790-PA 1 KEGG: 00780+2.6.1.62 "Biotin metabolism" EDAN012358-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN012465-PA 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" EDAN013591-PA 9 Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" EDAN007571-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN002291-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" EDAN000292-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN004697-PA 13 MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-6545 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" EDAN009402-PA 6 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation" EDAN002575-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" EDAN009616-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN017958-PA 20 KEGG: 04714+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-5218920;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-166208 "Thermogenesis";"Amino acids regulate mTORC1";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"Human papillomavirus infection";"HSF1-dependent transactivation";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"VEGFR2 mediated vascular permeability";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PIP3 activates AKT signaling";"Macroautophagy";"mTORC1-mediated signalling" EDAN008958-PA 5 Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787 "GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state" EDAN012467-PA 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" EDAN000320-PA 4 KEGG: 00780+2.3.1.47;MetaCyc: PWY-7147;MetaCyc: PWY-6578;MetaCyc: PWY-6519 "Biotin metabolism";"8-amino-7-oxononanoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis III";"8-amino-7-oxononanoate biosynthesis I" EDAN012434-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" EDAN003479-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN015843-PA 27 Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159230;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-77588;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-73856;Reactome: R-HSA-112382;Reactome: R-HSA-72187;Reactome: R-HSA-113418;Reactome: R-HSA-159227;Reactome: R-HSA-167200;Reactome: R-HSA-975956;Reactome: R-HSA-191859;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-159236;Reactome: R-HSA-72086;Reactome: R-HSA-111367 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of the SLBP Dependant Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Termination";"Formation of RNA Pol II elongation complex";"mRNA 3'-end processing";"Formation of the Early Elongation Complex";"Transport of the SLBP independent Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"snRNP Assembly";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Capping";"SLBP independent Processing of Histone Pre-mRNAs" EDAN003376-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN002632-PA 6 KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism" EDAN014137-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" EDAN017235-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN013153-PA 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" EDAN008406-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" EDAN018596-PA 1 Reactome: R-HSA-8935690 "Digestion" EDAN013372-PA 1 Reactome: R-HSA-390651 "Dopamine receptors" EDAN019296-PA 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" EDAN000422-PA 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" EDAN003212-PA 4 MetaCyc: PWY-7716;MetaCyc: PWY-6318;KEGG: 00360+6.2.1.30;MetaCyc: PWY-1341 "Penicillin G and penicillin V biosynthesis";"L-phenylalanine degradation IV (mammalian, via side chain)";"Phenylalanine metabolism";"Phenylacetate degradation II (anaerobic)" EDAN019039-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN018850-PA 11 MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-2201;Reactome: R-HSA-1296072;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Voltage gated Potassium channels";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes" EDAN018676-PA 10 KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559 "Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway" EDAN010512-PA 2 Reactome: R-HSA-3214841;Reactome: R-HSA-6783310 "PKMTs methylate histone lysines";"Fanconi Anemia Pathway" EDAN007457-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" EDAN000259-PA 11 MetaCyc: PWY-6607;MetaCyc: PWY-7821;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-5381;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5 "Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"Purine metabolism";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism" EDAN005722-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" EDAN006603-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" EDAN002450-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN011546-PA 4 Reactome: R-HSA-6782861;MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286 "Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" EDAN001199-PA 6 Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-388844 "Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" EDAN007232-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" EDAN018678-PA 5 KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7766;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" EDAN002570-PA 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" EDAN010477-PA 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" EDAN010267-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN007948-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" EDAN001947-PA 1 Reactome: R-HSA-3295583 "TRP channels" EDAN006761-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" EDAN003762-PA 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" EDAN010755-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN018165-PA 6 Reactome: R-HSA-2046106;Reactome: R-HSA-390247;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-9603798;Reactome: R-HSA-2046105 "alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Class I peroxisomal membrane protein import";"Linoleic acid (LA) metabolism" EDAN003207-PA 2 KEGG: 00340+4.3.2.10;KEGG: 00340+5.3.1.16 "Histidine metabolism";"Histidine metabolism" EDAN001014-PA 24 Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-392451 "ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma" EDAN015114-PA 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II" EDAN003126-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN015947-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN014960-PA 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" EDAN007440-PA 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" EDAN001643-PA 4 Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions" EDAN004335-PA 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway" EDAN019168-PA 8 MetaCyc: PWY-5154;MetaCyc: PWY-4983;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-5;Reactome: R-HSA-70635;MetaCyc: PWY-7400;KEGG: 00220+6.3.4.5 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Canavanine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis" EDAN000983-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" EDAN003453-PA 8 KEGG: 00710+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996;KEGG: 00030+5.3.1.6;Reactome: R-HSA-71336;MetaCyc: PWY-1861 "Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" EDAN004964-PA 27 Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142 "SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins" EDAN009485-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN017887-PA 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" EDAN002741-PA 56 Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783 "Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome" EDAN017661-PA 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" EDAN003914-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN005477-PA 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN016821-PA 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" EDAN013530-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" EDAN013827-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN007907-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN003115-PA 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" EDAN001497-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" EDAN017058-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN003290-PA 6 KEGG: 00130+4.1.1.98;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-6978;MetaCyc: PWY-5856 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)" EDAN000479-PA 11 KEGG: 00670+2.1.1.13;MetaCyc: PWY-3841;Reactome: R-HSA-156581;MetaCyc: PWY-2201;Reactome: R-HSA-3359467;Reactome: R-HSA-196741;Reactome: R-HSA-1614635;MetaCyc: PWY-7977;KEGG: 00450+2.1.1.13;KEGG: 00270+2.1.1.13;Reactome: R-HSA-3359469 "One carbon pool by folate";"Folate transformations II (plants)";"Methylation";"Folate transformations I";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Sulfur amino acid metabolism";"L-methionine biosynthesis IV (archaea)";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG" EDAN003239-PA 11 KEGG: 00270+2.1.1.13;Reactome: R-HSA-3359469;KEGG: 00450+2.1.1.13;Reactome: R-HSA-196741;Reactome: R-HSA-1614635;Reactome: R-HSA-3359467;MetaCyc: PWY-2201;MetaCyc: PWY-7977;Reactome: R-HSA-156581;MetaCyc: PWY-3841;KEGG: 00670+2.1.1.13 "Cysteine and methionine metabolism";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Selenocompound metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Sulfur amino acid metabolism";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Folate transformations I";"L-methionine biosynthesis IV (archaea)";"Methylation";"Folate transformations II (plants)";"One carbon pool by folate" EDAN008092-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN016061-PA 17 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" EDAN000650-PA 27 Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159236 "Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN018080-PA 1 KEGG: 00920+7.6.2.7 "Sulfur metabolism" EDAN000151-PA 6 KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336 "Pentose and glucuronate interconversions";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" EDAN017041-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN007369-PA 6 Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467 "Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs" EDAN019201-PA 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" EDAN015202-PA 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" EDAN015900-PA 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" EDAN009427-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN012661-PA 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" EDAN003087-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" EDAN008117-PA 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" EDAN004846-PA 26 Reactome: R-HSA-3899300;Reactome: R-HSA-3371568;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-918233;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-1989781;Reactome: R-HSA-210744;Reactome: R-HSA-933541;Reactome: R-HSA-9018519;Reactome: R-HSA-9617629;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856 "SUMOylation of transcription cofactors";"Attenuation phase";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"TRAF3-dependent IRF activation pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"PPARA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF6 mediated IRF7 activation";"Estrogen-dependent gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling" EDAN005550-PA 18 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4 "Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism" EDAN001950-PA 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" EDAN004751-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" EDAN003008-PA 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" EDAN010201-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" EDAN015129-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" EDAN016753-PA 10 MetaCyc: PWY-1861;KEGG: 00710+2.2.1.1;MetaCyc: PWY-6901;MetaCyc: PWY-7560;KEGG: 00030+2.2.1.1;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-5723;MetaCyc: PWY-6891 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Methylerythritol phosphate pathway II";"Pentose phosphate pathway";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Rubisco shunt";"Thiazole biosynthesis II (aerobic bacteria)" EDAN000476-PA 3 KEGG: 00920+2.5.1.47;MetaCyc: PWY-6936;KEGG: 00270+2.5.1.47 "Sulfur metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism" EDAN017827-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination" EDAN015263-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" EDAN005565-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN011666-PA 10 KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801 "Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Stachyose degradation";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)" EDAN001692-PA 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes" EDAN011208-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN009541-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN012707-PA 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" EDAN000085-PA 4 Reactome: R-HSA-204174;Reactome: R-HSA-1296072;Reactome: R-HSA-70895;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Voltage gated Potassium channels";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid" EDAN005779-PA 6 MetaCyc: PWY-4381;MetaCyc: PWY-8049;KEGG: 00061+2.3.1.39;MetaCyc: PWY-8047;MetaCyc: PWY-6799;MetaCyc: PWY-8012 "Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Fatty acid biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis" EDAN014021-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN011561-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" EDAN009753-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" EDAN014735-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN002181-PA 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" EDAN018244-PA 2 Reactome: R-HSA-8964539;KEGG: 00240+2.7.4.22 "Glutamate and glutamine metabolism";"Pyrimidine metabolism" EDAN017818-PA 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" EDAN015893-PA 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" EDAN006486-PA 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" EDAN016956-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN019302-PA 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" EDAN000222-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" EDAN017566-PA 6 Reactome: R-HSA-1614635;Reactome: R-HSA-196741;Reactome: R-HSA-3359467;KEGG: 00900+1.17.7.3;Reactome: R-HSA-156581;Reactome: R-HSA-3359469 "Sulfur amino acid metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Terpenoid backbone biosynthesis";"Methylation";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG" EDAN000149-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN004131-PA 14 Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167158 "TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex" EDAN015245-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" EDAN005229-PA 10 MetaCyc: PWY-6397;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7344;MetaCyc: PWY-7328 "Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" EDAN010583-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" EDAN010667-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" EDAN004769-PA 5 MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26 "Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Ether lipid metabolism" EDAN009682-PA 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" EDAN011660-PA 10 MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)" EDAN005054-PA 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus" EDAN000181-PA 7 MetaCyc: PWY-8004;MetaCyc: PWY-5514;Reactome: R-HSA-71336;KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906 "Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation" EDAN008128-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN003267-PA 5 MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-7082;MetaCyc: PWY-6692 "Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation" EDAN011613-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN007606-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN015317-PA 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" EDAN007586-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN019475-PA 13 KEGG: 00290+2.2.1.6;MetaCyc: PWY-5101;MetaCyc: PWY-5103;MetaCyc: PWY-5104;KEGG: 00290+4.2.1.9;KEGG: 00650+2.2.1.6;KEGG: 00770+2.2.1.6;MetaCyc: PWY-5938;MetaCyc: PWY-5939;MetaCyc: PWY-6389;KEGG: 00660+2.2.1.6;KEGG: 00770+4.2.1.9;MetaCyc: PWY-7111 "Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine biosynthesis";"Butanoate metabolism";"Pantothenate and CoA biosynthesis";"Pyruvate fermentation to (R)-acetoin I";"Pyruvate fermentation to (R)-acetoin II";"Pyruvate fermentation to (S)-acetoin";"C5-Branched dibasic acid metabolism";"Pantothenate and CoA biosynthesis";"Pyruvate fermentation to isobutanol (engineered)" EDAN000109-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN009630-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN007431-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" EDAN002776-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN018533-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN003143-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" EDAN019154-PA 3 KEGG: 00740+3.6.1.18;KEGG: 00230+3.6.1.13;Reactome: R-HSA-2393930 "Riboflavin metabolism";"Purine metabolism";"Phosphate bond hydrolysis by NUDT proteins" EDAN008615-PA 5 KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817;MetaCyc: PWY-5667 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I" EDAN006627-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" EDAN006245-PA 3 Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" EDAN015622-PA 12 MetaCyc: PWY-6708;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6978;MetaCyc: PWY-5856;Reactome: R-HSA-1268020;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5870 "Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" EDAN008823-PA 5 Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex" EDAN011406-PA 5 Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" EDAN012096-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN015057-PA 7 MetaCyc: PWY-8043;MetaCyc: PWY-6840;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999 "Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" EDAN015894-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN018903-PA 57 Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Degradation of AXIN" EDAN008072-PA 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" EDAN008891-PA 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN009588-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" EDAN000678-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" EDAN010673-PA 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" EDAN000558-PA 13 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00740+2.7.7.2;MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00860+4.2.1.24;MetaCyc: PWY-6167;KEGG: 00740+2.7.1.26+2.7.7.2;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-6798695;Reactome: R-HSA-196843 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Riboflavin metabolism";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Porphyrin and chlorophyll metabolism";"Flavin biosynthesis II (archaea)";"Riboflavin metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Neutrophil degranulation";"Vitamin B2 (riboflavin) metabolism" EDAN019340-PA 1 MetaCyc: PWY-6695 "Oxalate degradation II" EDAN014676-PA 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-202433 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules" EDAN003970-PA 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" EDAN012885-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN013792-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" EDAN012127-PA 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" EDAN019447-PA 5 MetaCyc: PWY-7953;MetaCyc: PWY-6387;KEGG: 00520+1.3.1.98;KEGG: 00550+1.3.1.98;MetaCyc: PWY-6386 "UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Amino sugar and nucleotide sugar metabolism";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)" EDAN008585-PA 58 Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5689901;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442 "Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Metalloprotease DUBs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Regulation of RAS by GAPs" EDAN014494-PA 5 KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" EDAN007478-PA 1 Reactome: R-HSA-1296061 "HCN channels" EDAN012226-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN018646-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN004422-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN015910-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" EDAN008074-PA 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" EDAN005551-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN008076-PA 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" EDAN011702-PA 2 KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19 "Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis" EDAN006928-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" EDAN008367-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN018805-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN014431-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN009932-PA 10 MetaCyc: PWY-6362;MetaCyc: PWY-6366;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;MetaCyc: PWY-6365;MetaCyc: PWY-6554;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.134+2.7.1.159;KEGG: 04070+2.7.1.159 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" EDAN002232-PA 20 MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7337 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Peroxisomal protein import";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)" EDAN006926-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" EDAN002080-PA 7 MetaCyc: PWY-6352;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6351 "3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" EDAN015042-PA 56 Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768 "Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"UCH proteinases";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" EDAN005776-PA 6 MetaCyc: PWY-5316;Reactome: R-HSA-611105;KEGG: 00760+1.4.3.16;MetaCyc: PWY-7342;KEGG: 00250+1.4.3.16;Reactome: R-HSA-71403 "Nicotine biosynthesis";"Respiratory electron transport";"Nicotinate and nicotinamide metabolism";"Superpathway of nicotine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Citric acid cycle (TCA cycle)" EDAN019089-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" EDAN010441-PA 4 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" EDAN002455-PA 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684 "Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state" EDAN006238-PA 8 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" EDAN012938-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN017427-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" EDAN019030-PA 12 KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-6672 "Pyruvate metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Propanoate metabolism";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Cis-genanyl-coa degradation" EDAN009546-PA 12 MetaCyc: PWY-5340;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932 "Sulfate activation for sulfonation";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Monobactam biosynthesis";"Purine metabolism";"Sulfur metabolism";"Sulfur metabolism";"Selenate reduction" EDAN005489-PA 13 Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" EDAN014357-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" EDAN004687-PA 14 Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4 "Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Ether lipid metabolism" EDAN004900-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" EDAN005820-PA 2 KEGG: 00400+4.2.3.5;MetaCyc: PWY-6163 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Chorismate biosynthesis from 3-dehydroquinate" EDAN005599-PA 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" EDAN018474-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN010247-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" EDAN014003-PA 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation" EDAN000060-PA 3 KEGG: 00340+1.1.1.23;KEGG: 00340+2.4.2.17;KEGG: 00340+4.2.1.19 "Histidine metabolism";"Histidine metabolism";"Histidine metabolism" EDAN009972-PA 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" EDAN011298-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits" EDAN011374-PA 1 Reactome: R-HSA-211981 "Xenobiotics" EDAN003049-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" EDAN015522-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN001452-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" EDAN000237-PA 4 Reactome: R-HSA-204174;Reactome: R-HSA-1296072;Reactome: R-HSA-70895;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Voltage gated Potassium channels";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid" EDAN005051-PA 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" EDAN004377-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" EDAN018969-PA 8 KEGG: 00220+6.3.4.5;MetaCyc: PWY-7400;Reactome: R-HSA-70635;MetaCyc: PWY-5;MetaCyc: PWY-4984;MetaCyc: PWY-5154;MetaCyc: PWY-4983;KEGG: 00250+6.3.4.5 "Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Canavanine biosynthesis";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism" EDAN019135-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN018587-PA 56 Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827 "Hedgehog 'on' state";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex" EDAN015090-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN013102-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" EDAN001772-PA 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" EDAN015024-PA 10 KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861 "Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" EDAN001302-PA 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" EDAN015059-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN010139-PA 2 Reactome: R-HSA-8934593;Reactome: R-HSA-69231 "Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1" EDAN017138-PA 12 MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II" EDAN017417-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN004220-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN001147-PA 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" EDAN000309-PA 17 MetaCyc: PWY-7383;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086 "Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Methane metabolism";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen" EDAN008729-PA 16 Reactome: R-HSA-167152;Reactome: R-HSA-1234176;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290 "Formation of HIV elongation complex in the absence of HIV Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation" EDAN012243-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN000620-PA 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN012957-PA 1 Reactome: R-HSA-189451 "Heme biosynthesis" EDAN008632-PA 22 Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813 "CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids" EDAN003754-PA 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" EDAN010096-PA 6 Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-8853383;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.25 "Neutrophil degranulation";"Hyaluronan uptake and degradation";"Lysosomal oligosaccharide catabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Other glycan degradation" EDAN009537-PA 18 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7205;Reactome: R-HSA-5624138;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7222 "Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Trafficking of myristoylated proteins to the cilium";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II" EDAN003367-PA 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" EDAN008291-PA 1 Reactome: R-HSA-8949613 "Cristae formation" EDAN003438-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN017840-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN010228-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN010666-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" EDAN004717-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN012511-PA 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" EDAN009792-PA 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" EDAN008275-PA 19 Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038 "Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"LDL remodeling";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"VLDL clearance";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Chylomicron remodeling";"VLDL assembly";"LDL clearance" EDAN000961-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN002601-PA 6 Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-69166 "HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate" EDAN003485-PA 18 MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482925 "Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG" EDAN012453-PA 6 MetaCyc: PWY-5789;MetaCyc: PWY-4381;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6722;Reactome: R-HSA-196780 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Candicidin biosynthesis";"Biotin transport and metabolism" EDAN007298-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN004059-PA 4 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" EDAN012378-PA 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" EDAN001019-PA 3 Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639 "Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis" EDAN003788-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN009661-PA 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" EDAN001039-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN008246-PA 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" EDAN011883-PA 5 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" EDAN015399-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" EDAN013488-PA 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" EDAN004756-PA 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" EDAN001845-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" EDAN018364-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" EDAN001473-PA 2 Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Pyrimidine salvage";"Pyrimidine catabolism" EDAN014203-PA 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1 "Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism" EDAN017994-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN006913-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" EDAN018748-PA 4 KEGG: 00970+6.1.1.3;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN012056-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN019411-PA 10 MetaCyc: PWY-7199;MetaCyc: PWY-3841;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;Reactome: R-HSA-69205;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00670+2.1.1.45;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleosides salvage";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"One carbon pool by folate";"Interconversion of nucleotide di- and triphosphates" EDAN017805-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN001071-PA 1 Reactome: R-HSA-171007 "p38MAPK events" EDAN007702-PA 16 Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" EDAN016150-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" EDAN001388-PA 7 MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201 "ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Cristae formation";"Oxidative phosphorylation";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis" EDAN013448-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN013714-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" EDAN003227-PA 5 MetaCyc: PWY-6167;Reactome: R-HSA-196757;MetaCyc: PWY-6168;MetaCyc: PWY-7991;KEGG: 00740+3.5.4.26+1.1.1.193 "Flavin biosynthesis II (archaea)";"Metabolism of folate and pterines";"Flavin biosynthesis III (fungi)";"Toxoflavin biosynthesis";"Riboflavin metabolism" EDAN005808-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN002733-PA 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" EDAN000088-PA 10 Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9 "Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes" EDAN017131-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" EDAN010169-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" EDAN016675-PA 4 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" EDAN008156-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN004573-PA 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" EDAN007350-PA 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" EDAN018958-PA 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" EDAN010476-PA 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691 "T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling" EDAN003277-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN002479-PA 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" EDAN016008-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN001902-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN005025-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN019068-PA 14 Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5656121 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Polymerase switching";"Translesion synthesis by POLI" EDAN009147-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" EDAN005203-PA 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" EDAN019244-PA 5 KEGG: 00620+2.7.9.2;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00680+2.7.9.2;KEGG: 00720+2.7.9.2 "Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Carbon fixation pathways in prokaryotes" EDAN015097-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" EDAN018594-PA 14 KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-7279;Reactome: R-HSA-71403 "Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)" EDAN014234-PA 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" EDAN004767-PA 5 MetaCyc: PWY-7782;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896 "Plasmalogen biosynthesis";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis" EDAN010142-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN008936-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN017963-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN015642-PA 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" EDAN000817-PA 3 KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" EDAN002378-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN009499-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN010679-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN003009-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN002554-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN000076-PA 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" EDAN004869-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN002264-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN013390-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN009229-PA 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" EDAN001241-PA 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" EDAN000831-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" EDAN001380-PA 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" EDAN012888-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" EDAN003907-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN008007-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN004906-PA 15 Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897 "MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes" EDAN008297-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN002985-PA 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" EDAN003632-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN006806-PA 6 MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" EDAN000382-PA 3 MetaCyc: PWY-1269;KEGG: 00540+3.1.3.45;MetaCyc: PWY-7674 "CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis";"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis" EDAN004015-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN000379-PA 7 Reactome: R-HSA-4549349;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-446193;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism" EDAN000099-PA 31 MetaCyc: PWY-6387;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;KEGG: 00550+6.3.2.4;KEGG: 00473+6.3.2.4;Reactome: R-HSA-8949613;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;MetaCyc: PWY-7953;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-1268020;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;MetaCyc: PWY-6386;Reactome: R-HSA-5663220 "UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Peptidoglycan biosynthesis";"D-Alanine metabolism";"Cristae formation";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Cilium Assembly";"Aggrephagy";"Kinesins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitochondrial protein import";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"RHO GTPases Activate Formins" EDAN014107-PA 12 Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6804756 "Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation" EDAN011335-PA 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" EDAN013304-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN008118-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN002852-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN018339-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN011697-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" EDAN008481-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN012407-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" EDAN003257-PA 3 Reactome: R-HSA-70895;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN013024-PA 18 Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167160 "Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" EDAN018397-PA 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" EDAN003916-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" EDAN014238-PA 1 Reactome: R-HSA-8949613 "Cristae formation" EDAN006652-PA 4 KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" EDAN005680-PA 5 MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" EDAN012507-PA 10 Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-9022692 "Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity" EDAN007700-PA 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" EDAN000815-PA 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" EDAN003206-PA 5 KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00340+4.3.2.10 "Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Histidine metabolism" EDAN013977-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN001576-PA 4 KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331 "Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I" EDAN019094-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" EDAN000047-PA 2 KEGG: 00730+4.1.99.17;MetaCyc: PWY-6890 "Thiamine metabolism";"4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis" EDAN017831-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" EDAN001986-PA 4 Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710 "Aggrephagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Late endosomal microautophagy" EDAN016129-PA 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" EDAN016361-PA 40 MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6863;MetaCyc: PWY-6945;MetaCyc: PWY-6583;MetaCyc: PWY-5789;MetaCyc: PWY-7654;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6946;MetaCyc: PWY-6883;KEGG: 00410+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5136;MetaCyc: PWY-1361;KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00281+4.2.1.17+1.1.1.35 "Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Limonene and pinene degradation";"2-methylpropene degradation";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Pyruvate fermentation to butanol I";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"Aminobenzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"Fatty acid elongation";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid salvage";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"beta-Alanine metabolism";"Caprolactam degradation";"Benzoate degradation";"Butanoate metabolism";"Androstenedione degradation";"Toluene degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Tryptophan metabolism";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoyl-coa degradation I (aerobic)";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Glutaryl-coa degradation";"Geraniol degradation" EDAN017920-PA 15 MetaCyc: PWY-7384;MetaCyc: PWY-4381;Reactome: R-HSA-3371599;MetaCyc: PWY-6728;KEGG: 00630+6.4.1.3;KEGG: 00280+6.4.1.3;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.3;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWYG-321;Reactome: R-HSA-71032;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.3;MetaCyc: PWY-6722 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Defective HLCS causes multiple carboxylase deficiency";"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"";"Propionyl-CoA catabolism";"Glyoxylate assimilation";"Propanoate metabolism";"Candicidin biosynthesis" EDAN010400-PA 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" EDAN005094-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" EDAN008470-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" EDAN003663-PA 6 MetaCyc: PWY-6829;Reactome: R-HSA-6787450;MetaCyc: PWY-7285;Reactome: R-HSA-8868766;MetaCyc: PWY-7286;Reactome: R-HSA-6785470 "Trna methylation (yeast)";"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion" EDAN014249-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" EDAN018983-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" EDAN009288-PA 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" EDAN008341-PA 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" EDAN011910-PA 7 MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" EDAN000159-PA 14 Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5656121 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Translesion synthesis by POLI" EDAN015178-PA 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" EDAN003203-PA 2 KEGG: 00340+2.4.2.17;KEGG: 00340+1.1.1.23 "Histidine metabolism";"Histidine metabolism" EDAN010638-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN006754-PA 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN010493-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" EDAN019406-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN009755-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" EDAN017729-PA 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" EDAN015635-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN015592-PA 5 MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273 "Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" EDAN005590-PA 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" EDAN004629-PA 14 Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5685942 "PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Polymerase switching";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)" EDAN016026-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN006227-PA 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" EDAN018634-PA 8 MetaCyc: PWY-702;MetaCyc: PWY-5041;MetaCyc: PWY-6936;KEGG: 00450+2.1.1.14;MetaCyc: PWY-5188;KEGG: 00270+2.1.1.14;KEGG: 00860+1.2.1.70;MetaCyc: PWY-6151 "L-methionine biosynthesis II (plants)";"S-adenosyl-L-methionine cycle II";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cysteine and methionine metabolism";"Porphyrin and chlorophyll metabolism";"S-adenosyl-L-methionine cycle I" EDAN000293-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" EDAN019309-PA 10 KEGG: 00020+1.2.4.2;KEGG: 00020+2.3.1.61;KEGG: 00310+1.2.4.2;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61 "Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" EDAN007944-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" EDAN011274-PA 57 Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837 "CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation" EDAN010327-PA 3 MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" EDAN007569-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN018219-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN007608-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN003499-PA 5 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)" EDAN000875-PA 8 KEGG: 00051+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996 "Fructose and mannose metabolism";"Rubisco shunt";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P" EDAN012198-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN004870-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN006530-PA 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" EDAN002015-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN017052-PA 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" EDAN019529-PA 3 KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2 "Photosynthesis";"ATP biosynthesis";"Oxidative phosphorylation" EDAN001731-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" EDAN017174-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN010218-PA 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" EDAN003036-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" EDAN001605-PA 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN005297-PA 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" EDAN004405-PA 6 Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN005754-PA 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" EDAN004740-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN002380-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN002278-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" EDAN006000-PA 5 Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571 "Neutrophil degranulation";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)" EDAN003801-PA 3 Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex" EDAN001282-PA 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" EDAN002401-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN015605-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" EDAN006734-PA 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" EDAN010739-PA 3 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" EDAN016919-PA 29 KEGG: 05163+2.7.11.1;Reactome: R-HSA-69541;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-6796648;Reactome: R-HSA-349425;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6803207;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-6803204;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760 "Human cytomegalovirus infection";"Stabilization of p53";"Thermogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Human papillomavirus infection";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation" EDAN006182-PA 20 MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288 "Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)" EDAN001301-PA 3 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" EDAN009354-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN005409-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN001217-PA 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350 "Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism" EDAN005848-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN009414-PA 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" EDAN015237-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN004022-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN005711-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN009137-PA 1 Reactome: R-HSA-8856825 "Cargo recognition for clathrin-mediated endocytosis" EDAN000428-PA 4 KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004 "Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I" EDAN011829-PA 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" EDAN000084-PA 6 Reactome: R-HSA-70895;Reactome: R-HSA-5362517;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-204174;Reactome: R-HSA-1296072 "Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Voltage gated Potassium channels" EDAN000069-PA 12 MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5872;Reactome: R-HSA-1268020;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-6708;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5873 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)" EDAN011340-PA 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" EDAN010534-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" EDAN016656-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" EDAN005568-PA 6 Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway";"Pentose and glucuronate interconversions" EDAN006320-PA 6 Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36 "Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" EDAN002456-PA 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" EDAN017390-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN015536-PA 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" EDAN017468-PA 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2132295 "Condensation of Prometaphase Chromosomes";"MHC class II antigen presentation" EDAN000231-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN010301-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006116-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" EDAN009580-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN004854-PA 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" EDAN012956-PA 8 Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867 "CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex" EDAN015728-PA 3 KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347 "Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" EDAN011938-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" EDAN009618-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN005852-PA 3 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" EDAN013914-PA 19 MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969 "Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" EDAN004108-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN005745-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN006390-PA 24 Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609690 "Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Cilium Assembly";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"HCMV Early Events" EDAN011241-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" EDAN005819-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" EDAN001127-PA 27 Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" EDAN009068-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" EDAN006929-PA 8 Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111459 "Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage" EDAN007613-PA 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" EDAN001532-PA 56 Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815 "Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D" EDAN001387-PA 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism" EDAN018531-PA 4 Reactome: R-HSA-5362517;Reactome: R-HSA-70895;Reactome: R-HSA-1296072;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"Voltage gated Potassium channels";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN015366-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" EDAN009823-PA 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" EDAN005148-PA 3 Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis" EDAN004713-PA 3 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism" EDAN015573-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN006904-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN002670-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN017913-PA 10 Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" EDAN013758-PA 4 Reactome: R-HSA-8964011;Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463 "HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1" EDAN004438-PA 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" EDAN017867-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN007092-PA 27 Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-165054 "tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA" EDAN003854-PA 6 Reactome: R-HSA-69205;MetaCyc: PWY-7199;KEGG: 00983+2.7.1.21;Reactome: R-HSA-8876198;KEGG: 00240+2.7.1.21;Reactome: R-HSA-73614 "G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"RAB GEFs exchange GTP for GDP on RABs";"Pyrimidine metabolism";"Pyrimidine salvage" EDAN005804-PA 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" EDAN011039-PA 4 MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803 "Anandamide biosynthesis I";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing" EDAN012170-PA 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" EDAN011538-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN006640-PA 4 Reactome: R-HSA-937039;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702 "IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling" EDAN005668-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN018804-PA 2 KEGG: 00561+2.3.1.274;MetaCyc: PWY-5981 "Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III" EDAN016110-PA 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" EDAN006970-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN005090-PA 29 Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-3371453;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696395 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Meiotic recombination";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Regulation of HSF1-mediated heat shock response";"Dual Incision in GG-NER";"HSF1 activation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Formation of Incision Complex in GG-NER" EDAN000063-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN010572-PA 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine" EDAN013872-PA 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" EDAN018643-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN010051-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN006104-PA 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" EDAN002084-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN005763-PA 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" EDAN013152-PA 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" EDAN018782-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN010281-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN013386-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN002833-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN006918-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN000607-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN013976-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN000870-PA 13 Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902 "Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)" EDAN001727-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN018304-PA 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" EDAN002645-PA 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway" EDAN005300-PA 15 KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-1042 "Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis IV (plant cytosol)" EDAN003185-PA 12 Reactome: R-HSA-71032;KEGG: 00640+6.4.1.3;MetaCyc: PWYG-321;KEGG: 00720+6.4.1.3;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-7384;Reactome: R-HSA-3371599;MetaCyc: PWY-6728;KEGG: 00280+6.4.1.3;KEGG: 00630+6.4.1.3;MetaCyc: PWY-5789 "Propionyl-CoA catabolism";"Propanoate metabolism";"";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Defective HLCS causes multiple carboxylase deficiency";"Methylaspartate cycle";"Valine, leucine and isoleucine degradation";"Glyoxylate and dicarboxylate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" EDAN011111-PA 7 KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7219 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis" EDAN000305-PA 6 KEGG: 00550+2.4.1.129+3.4.16.4;KEGG: 00550+2.4.1.129;MetaCyc: PWY-5265;MetaCyc: PWY-6470;MetaCyc: PWY-6385;MetaCyc: PWY-6471 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" EDAN018825-PA 5 Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" EDAN007260-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN010682-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN017438-PA 16 Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-8853884 "Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX" EDAN016562-PA 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" EDAN008487-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" EDAN011653-PA 5 KEGG: 00540+2.5.1.55;KEGG: 00400+2.5.1.54;MetaCyc: PWY-6164;MetaCyc: PWY-1269;MetaCyc: PWY-7674 "Lipopolysaccharide biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"3-dehydroquinate biosynthesis I";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis" EDAN011436-PA 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" EDAN014488-PA 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" EDAN019246-PA 5 MetaCyc: PWY-7674;MetaCyc: PWY-1269;MetaCyc: PWY-6164;KEGG: 00400+2.5.1.54;KEGG: 00540+2.5.1.55 "CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"3-dehydroquinate biosynthesis I";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Lipopolysaccharide biosynthesis" EDAN018640-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN006099-PA 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" EDAN014880-PA 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" EDAN018767-PA 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" EDAN015979-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN012294-PA 8 Reactome: R-HSA-6811438;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-532668;Reactome: R-HSA-901042 "Intra-Golgi traffic";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle" EDAN006064-PA 7 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1" EDAN013813-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN003349-PA 10 Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473 "SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint" EDAN011580-PA 7 Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208 "Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling" EDAN006973-PA 13 KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-2261;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;KEGG: 00053+1.8.5.1 "Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate and aldarate metabolism" EDAN019369-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN011714-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" EDAN017899-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN019251-PA 14 Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096 "Amyloid fiber formation";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Neutrophil degranulation";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus" EDAN002876-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN012163-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN004624-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN005299-PA 2 MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" EDAN004161-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" EDAN008186-PA 20 MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7288 "(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)" EDAN008277-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN008195-PA 8 MetaCyc: PWY-5723;Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;MetaCyc: PWY-1861;Reactome: R-HSA-71336 "Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" EDAN019056-PA 15 Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-416476;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-1433557 "Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"RET signaling";"Regulation of signaling by CBL";"G alpha (q) signalling events";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"Signaling by SCF-KIT" EDAN008603-PA 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" EDAN010538-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" EDAN000639-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" EDAN002203-PA 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation" EDAN005781-PA 2 KEGG: 00561+2.3.1.274;MetaCyc: PWY-5981 "Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III" EDAN008516-PA 19 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-3214858;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Protein methylation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" EDAN006741-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" EDAN005714-PA 11 MetaCyc: PWY-7821;MetaCyc: PWY-6607;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-5381;MetaCyc: PWY-6606;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5 "Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Purine metabolism" EDAN005753-PA 14 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-110320 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH" EDAN003058-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN008854-PA 13 Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-389357;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208 "Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"CD28 dependent PI3K/Akt signaling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling" EDAN014004-PA 3 Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" EDAN010271-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN017147-PA 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" EDAN014913-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN002052-PA 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" EDAN005920-PA 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" EDAN010514-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" EDAN015942-PA 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" EDAN018741-PA 3 KEGG: 00430+1.4.1.1;Reactome: R-HSA-71403;KEGG: 00250+1.4.1.1 "Taurine and hypotaurine metabolism";"Citric acid cycle (TCA cycle)";"Alanine, aspartate and glutamate metabolism" EDAN004533-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" EDAN001082-PA 6 Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73930 "Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" EDAN019400-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" EDAN004746-PA 4 Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040 "G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation" EDAN005023-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN005712-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN014153-PA 11 Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"COPI-mediated anterograde transport" EDAN013549-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN010571-PA 6 Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-416993 "COPII-mediated vesicle transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors" EDAN010697-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" EDAN017706-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" EDAN003373-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN016053-PA 24 Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736 "Cilium Assembly";"Aggrephagy";"HCMV Early Events";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors" EDAN019401-PA 5 MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-7082;MetaCyc: PWY-6692 "Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation" EDAN002222-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN014605-PA 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation" EDAN003661-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN005717-PA 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" EDAN001109-PA 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" EDAN012944-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" EDAN000194-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN015134-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" EDAN019467-PA 7 KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7400;MetaCyc: PWY-5154;MetaCyc: PWY-7791;MetaCyc: PWY-5686 "Pyrimidine metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III";"UMP biosynthesis I" EDAN000555-PA 7 MetaCyc: PWY-6614;KEGG: 00790+2.5.1.15;Reactome: R-HSA-196741;Reactome: R-HSA-3359467;Reactome: R-HSA-1614635;Reactome: R-HSA-3359469;Reactome: R-HSA-156581 "Tetrahydrofolate biosynthesis";"Folate biosynthesis";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Sulfur amino acid metabolism";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Methylation" EDAN005693-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN018974-PA 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" EDAN000677-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN008827-PA 8 Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111459 "Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage" EDAN001571-PA 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" EDAN010821-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN006013-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN012389-PA 15 Reactome: R-HSA-9665233;Reactome: R-HSA-9664565;Reactome: R-HSA-9652282;Reactome: R-HSA-9665251;Reactome: R-HSA-1227986;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-1236382;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-8863795;Reactome: R-HSA-5637810;Reactome: R-HSA-9665246 "Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2 KD Mutants";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to lapatinib";"Signaling by ERBB2";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Downregulation of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to neratinib" EDAN009696-PA 7 Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737 "Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation II";"Starch and sucrose metabolism";"Starch degradation V" EDAN010097-PA 5 MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-7863 "5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis" EDAN004128-PA 4 Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-2162123 "Neutrophil degranulation";"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" EDAN012727-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN013853-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN014975-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" EDAN005671-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN016370-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" EDAN002569-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" EDAN000544-PA 18 KEGG: 00260+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70268;Reactome: R-HSA-71403;KEGG: 00640+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00010+1.8.1.4;Reactome: R-HSA-389661;MetaCyc: PWY-5046;Reactome: R-HSA-5362517;Reactome: R-HSA-71064;Reactome: R-HSA-204174;KEGG: 00310+1.8.1.4;MetaCyc: PWY-5084 "Glycine, serine and threonine metabolism";"Branched-chain amino acid catabolism";"Tryptophan metabolism";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine degradation";"Pyruvate metabolism";"Glycine degradation";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Signaling by Retinoic Acid";"Lysine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" EDAN000302-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN004142-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" EDAN000074-PA 2 MetaCyc: PWY-7560;KEGG: 00900+1.17.7.4 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" EDAN008873-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" EDAN001318-PA 4 Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" EDAN007382-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN002254-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN005733-PA 14 MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-7279;Reactome: R-HSA-71403 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)" EDAN005571-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" EDAN003408-PA 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN010410-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN009355-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" EDAN004835-PA 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" EDAN013892-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN017583-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN016698-PA 16 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-180585 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G" EDAN014538-PA 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" EDAN018233-PA 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" EDAN001372-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" EDAN004394-PA 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" EDAN013097-PA 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" EDAN017164-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" EDAN007826-PA 5 Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" EDAN014272-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" EDAN007714-PA 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" EDAN002185-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN010637-PA 6 KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020 "Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import" EDAN006233-PA 11 Reactome: R-HSA-164378;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-163615 "PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation" EDAN003269-PA 14 Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" EDAN013627-PA 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105 "Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation" EDAN000916-PA 13 Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN014271-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" EDAN013842-PA 1 Reactome: R-HSA-1483191 "Synthesis of PC" EDAN001927-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN008201-PA 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" EDAN005825-PA 2 KEGG: 00410+6.3.2.1;KEGG: 00770+6.3.2.1 "beta-Alanine metabolism";"Pantothenate and CoA biosynthesis" EDAN015799-PA 6 Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241 "Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import" EDAN003423-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN013371-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN005669-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN018669-PA 5 KEGG: 00380+1.11.1.21;KEGG: 00940+1.11.1.21;KEGG: 00360+1.11.1.21;MetaCyc: PWY-5506;KEGG: 00983+1.11.1.21 "Tryptophan metabolism";"Phenylpropanoid biosynthesis";"Phenylalanine metabolism";"Methanol oxidation to formaldehyde IV";"Drug metabolism - other enzymes" EDAN009232-PA 5 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" EDAN016750-PA 22 MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-8004;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism" EDAN016674-PA 6 KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23 "Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism" EDAN017946-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN001331-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" EDAN004839-PA 7 Reactome: R-HSA-1483226;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625 "Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)" EDAN010808-PA 2 Reactome: R-HSA-375276;Reactome: R-HSA-418555 "Peptide ligand-binding receptors";"G alpha (s) signalling events" EDAN016224-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN005894-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN019075-PA 4 Reactome: R-HSA-70895;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-1296072 "Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Voltage gated Potassium channels" EDAN009183-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" EDAN005290-PA 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" EDAN000427-PA 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" EDAN004354-PA 7 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052 "Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis" EDAN006659-PA 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" EDAN013407-PA 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" EDAN009620-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" EDAN014997-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" EDAN007766-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" EDAN012265-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN000829-PA 16 Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174178 "Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" EDAN014383-PA 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" EDAN012930-PA 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination" EDAN008623-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN005141-PA 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" EDAN002627-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN004016-PA 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" EDAN010707-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN005698-PA 40 MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-5789;MetaCyc: PWY-7654;MetaCyc: PWY-6945;MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6863;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7216;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6883;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7094;MetaCyc: PWY-7401;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007 "Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid degradation";"Aminobenzoate degradation";"Pyruvate fermentation to butanol I";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Limonene and pinene degradation";"2-methylpropene degradation";"Pyruvate fermentation to hexanol (engineered)";"alpha-Linolenic acid metabolism";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Geraniol degradation";"Benzoyl-coa degradation I (aerobic)";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"Tryptophan metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Butanoate metabolism";"Androstenedione degradation";"Toluene degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Pyruvate fermentation to butanol II (engineered)";"Caprolactam degradation";"beta-Alanine metabolism";"Benzoate degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid salvage";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)" EDAN000708-PA 34 Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-69273;Reactome: R-HSA-69202;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-77075 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin E associated events during G1/S transition";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE" EDAN013687-PA 13 KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220 "Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" EDAN012254-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" EDAN009577-PA 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099 "Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling" EDAN012038-PA 8 Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68689 "Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex" EDAN001432-PA 32 Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6796648 "mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes" EDAN013558-PA 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" EDAN001503-PA 3 Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine" EDAN003103-PA 3 Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" EDAN011696-PA 52 Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-76066;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-168325;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-112382 "Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex" EDAN003199-PA 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN018751-PA 14 KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-181;MetaCyc: PWY-1622;KEGG: 00460+2.1.2.1;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757 "Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Folate transformations II (plants)";"Glycine betaine degradation I";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Folate transformations I";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Cyanoamino acid metabolism";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines" EDAN000280-PA 4 KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17 "Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis" EDAN003974-PA 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" EDAN004726-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN015029-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN010480-PA 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" EDAN007749-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN018306-PA 14 KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-8055;Reactome: R-HSA-75109;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052 "Ether lipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Synthesis of PC";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis" EDAN011224-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN014569-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN003999-PA 17 Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-8951664;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174178 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Neddylation";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" EDAN010483-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN016204-PA 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" EDAN014496-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN015537-PA 13 MetaCyc: PWY-8086;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)" EDAN009081-PA 8 MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" EDAN006412-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN018341-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN006954-PA 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" EDAN003347-PA 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7 "Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism" EDAN002495-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN007439-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" EDAN013963-PA 3 Reactome: R-HSA-5603037;Reactome: R-HSA-168142;Reactome: R-HSA-975871 "IRAK4 deficiency (TLR5)";"Toll Like Receptor 10 (TLR10) Cascade";"MyD88 cascade initiated on plasma membrane" EDAN007958-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" EDAN017817-PA 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" EDAN008785-PA 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" EDAN004445-PA 5 MetaCyc: PWY-6853;Reactome: R-HSA-70688;Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88 "Ethylene biosynthesis II (microbes)";"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism" EDAN009028-PA 10 MetaCyc: PWY-7661;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-913709;Reactome: R-HSA-4719377 "Protein N-glycosylation (Haloferax volcanii)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"N-Glycan biosynthesis";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"O-linked glycosylation of mucins";"Defective DPM2 causes DPM2-CDG (CDG-1u)" EDAN018299-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" EDAN000438-PA 4 MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" EDAN004937-PA 1 Reactome: R-HSA-977443 "GABA receptor activation" EDAN007032-PA 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" EDAN005376-PA 4 Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN019513-PA 3 KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980 "Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis" EDAN000781-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" EDAN000201-PA 14 KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;MetaCyc: PWY-5497;KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3841 "Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Methane metabolism";"Folate transformations I";"Photorespiration ";"Folate polyglutamylation";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Purine nucleobases degradation II (anaerobic)";"Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Folate transformations II (plants)" EDAN017181-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" EDAN009793-PA 1 Reactome: R-HSA-1483148 "Synthesis of PG" EDAN012722-PA 15 Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-176034 "Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Interactions of Tat with host cellular proteins" EDAN011873-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN015873-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN007598-PA 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1 "Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism" EDAN015502-PA 3 Reactome: R-HSA-204005;Reactome: R-HSA-948021;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER" EDAN009557-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" EDAN003213-PA 13 MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5538 "Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI" EDAN009852-PA 13 MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-6613;MetaCyc: PWY-5030 "Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III" EDAN011909-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN007977-PA 5 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" EDAN006543-PA 3 Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20 "Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism" EDAN017918-PA 4 Reactome: R-HSA-3359478;Reactome: R-HSA-71032;Reactome: R-HSA-196741;Reactome: R-HSA-3359475 "Defective MUT causes methylmalonic aciduria mut type";"Propionyl-CoA catabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAA causes methylmalonic aciduria type cblA" EDAN011678-PA 5 MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis" EDAN000248-PA 6 MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-1663150;Reactome: R-HSA-1660662;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"The activation of arylsulfatases";"Glycosphingolipid metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" EDAN002515-PA 9 Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" EDAN014172-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" EDAN013008-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN005937-PA 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" EDAN003168-PA 21 Reactome: R-HSA-975956;MetaCyc: PWY-2201;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-196757;Reactome: R-HSA-1799339;KEGG: 00720+1.5.1.20;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;KEGG: 00670+1.5.1.20;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;MetaCyc: PWY-3841;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Folate transformations I";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Metabolism of folate and pterines";"SRP-dependent cotranslational protein targeting to membrane";"Carbon fixation pathways in prokaryotes";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"One carbon pool by folate";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Folate transformations II (plants)";"Regulation of expression of SLITs and ROBOs" EDAN005363-PA 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" EDAN010687-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN007315-PA 8 KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1 "Fructose and mannose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis" EDAN003392-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN000580-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN019125-PA 34 Reactome: R-HSA-72689;MetaCyc: PWY-7184;Reactome: R-HSA-72702;Reactome: R-HSA-72649;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7226;Reactome: R-HSA-9010553;MetaCyc: PWY-7220;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;Reactome: R-HSA-72695;MetaCyc: PWY-7176;Reactome: R-HSA-6791226;MetaCyc: PWY-7205;Reactome: R-HSA-156902;MetaCyc: PWY-7187;MetaCyc: PWY-7197;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72706;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;MetaCyc: PWY-7222;Reactome: R-HSA-72764;Reactome: R-HSA-156827;MetaCyc: PWY-7227;Reactome: R-HSA-1799339;MetaCyc: PWY-6545;MetaCyc: PWY-7221 "Formation of a pool of free 40S subunits";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Regulation of expression of SLITs and ROBOs";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Formation of the ternary complex, and subsequently, the 43S complex";"UTP and CTP de novo biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"CMP phosphorylation";"Peptide chain elongation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Adenosine deoxyribonucleotides de novo biosynthesis";"SRP-dependent cotranslational protein targeting to membrane";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis" EDAN006143-PA 6 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation" EDAN006444-PA 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" EDAN003429-PA 10 Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-3299685 "TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species" EDAN011719-PA 22 Reactome: R-HSA-6798695;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.9;Reactome: R-HSA-70263;Reactome: R-HSA-5628897;MetaCyc: PWY-5659;MetaCyc: PWY-7347;MetaCyc: PWY-5384;MetaCyc: PWY-5514;MetaCyc: PWY-3801;MetaCyc: PWY-8013;MetaCyc: PWY-7238;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6981;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.9;MetaCyc: PWY-621;MetaCyc: PWY-7385;MetaCyc: PWY-5054;Reactome: R-HSA-70171;MetaCyc: PWY-622 "Neutrophil degranulation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"TP53 Regulates Metabolic Genes";"GDP-mannose biosynthesis";"Sucrose biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Chitin biosynthesis";"Pentose phosphate pathway";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation III (sucrose invertase)";"1,3-propanediol biosynthesis (engineered)";"D-sorbitol biosynthesis I";"Glycolysis";"Starch biosynthesis" EDAN019124-PA 5 MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I" EDAN001981-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN004738-PA 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" EDAN009120-PA 1 Reactome: R-HSA-3000171 "Non-integrin membrane-ECM interactions" EDAN015779-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN011807-PA 16 Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174178 "Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" EDAN003750-PA 10 MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes" EDAN002975-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" EDAN009697-PA 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" EDAN012861-PA 15 Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692 "Oxidative Stress Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity" EDAN001827-PA 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" EDAN012823-PA 1 Reactome: R-HSA-3295583 "TRP channels" EDAN006710-PA 8 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" EDAN012169-PA 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" EDAN017575-PA 2 MetaCyc: PWY-5344;KEGG: 00270+2.3.1.31 "L-homocysteine biosynthesis";"Cysteine and methionine metabolism" EDAN011143-PA 3 Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902 "Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity" EDAN008510-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN010362-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" EDAN004167-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN017843-PA 4 MetaCyc: PWY-5958;KEGG: 00400+4.1.3.27;MetaCyc: PWY-6661;KEGG: 00405+4.1.3.27 "Acridone alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"4-hydroxy-2(1H)-quinolone biosynthesis";"Phenazine biosynthesis" EDAN018455-PA 27 Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854 "SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly" EDAN003462-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN014062-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" EDAN000401-PA 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" EDAN000357-PA 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" EDAN014389-PA 56 Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783 "Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome" EDAN018070-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN018967-PA 3 Reactome: R-HSA-499943;MetaCyc: PWY-1361;KEGG: 00362+1.14.13.208 "Interconversion of nucleotide di- and triphosphates";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation" EDAN008556-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN017201-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN010868-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN012154-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN005593-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN003407-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" EDAN000233-PA 2 MetaCyc: PWY-5188;KEGG: 00860+5.4.3.8 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" EDAN003244-PA 3 Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" EDAN013245-PA 11 Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-1268020;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-9627069 "Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity" EDAN016372-PA 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" EDAN002488-PA 3 Reactome: R-HSA-913709;Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "O-linked glycosylation of mucins";"N-Glycan antennae elongation";"Keratan sulfate biosynthesis" EDAN014839-PA 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171 "ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Non-integrin membrane-ECM interactions" EDAN011587-PA 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" EDAN015115-PA 37 Reactome: R-HSA-983170;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-2132295;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-204005;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-9639288;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-2500257 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"MHC class II antigen presentation";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"COPII-mediated vesicle transport";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Amino acids regulate mTORC1";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion" EDAN011455-PA 29 Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-73762;Reactome: R-HSA-167246 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript" EDAN019332-PA 7 Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-5620922 "Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium" EDAN001828-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" EDAN003647-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN005445-PA 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" EDAN004321-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN010055-PA 2 Reactome: R-HSA-430039;MetaCyc: PWY-6938 "mRNA decay by 5' to 3' exoribonuclease";"NADH repair" EDAN005185-PA 6 Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827 "Dual incision in TC-NER";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" EDAN005718-PA 14 MetaCyc: PWY-6562;MetaCyc: PWY-7153;KEGG: 00270+2.7.2.4;MetaCyc: PWY-7977;MetaCyc: PWY-2941;KEGG: 00260+2.7.2.4;MetaCyc: PWY-5097;KEGG: 00300+2.7.2.4;MetaCyc: PWY-6559;KEGG: 00261+2.7.2.4;MetaCyc: PWY-2942;MetaCyc: PWY-6160;Reactome: R-HSA-8964539;MetaCyc: PWY-8088 "Norspermidine biosynthesis";"Grixazone biosynthesis";"Cysteine and methionine metabolism";"L-methionine biosynthesis IV (archaea)";"L-lysine biosynthesis II";"Glycine, serine and threonine metabolism";"L-lysine biosynthesis VI";"Lysine biosynthesis";"Spermidine biosynthesis II";"Monobactam biosynthesis";"L-lysine biosynthesis III";"3-dehydroquinate biosynthesis II (archaea)";"Glutamate and glutamine metabolism";"Dipicolinate biosynthesis" EDAN008044-PA 9 MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5664;MetaCyc: PWY-6983 "Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis" EDAN005697-PA 42 KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+1.3.8.8+1.3.8.7;MetaCyc: PWY-5177;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7606;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5136;KEGG: 00280+1.3.8.7;MetaCyc: PWY-6946;KEGG: 00410+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7094;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00627+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6945;MetaCyc: PWY-5789;MetaCyc: PWY-6583;MetaCyc: PWY-7654;MetaCyc: PWY-7778;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-5109;MetaCyc: PWY-7726 "Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Benzoyl-coa degradation I (aerobic)";"Geraniol degradation";"Fatty acid degradation";"Glutaryl-coa degradation";"alpha-Linolenic acid metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Androstenedione degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Butanoate metabolism";"Tryptophan metabolism";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"beta-Alanine metabolism";"Caprolactam degradation";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid salvage";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"Aminobenzoate degradation";"Fatty acid degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"2-methylpropene degradation";"Limonene and pinene degradation";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" EDAN005841-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" EDAN013194-PA 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" EDAN009760-PA 5 Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT" EDAN004750-PA 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" EDAN005824-PA 2 KEGG: 00770+2.1.2.11;MetaCyc: PWY-6654 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis III (archaebacteria)" EDAN012410-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN004386-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN011699-PA 14 MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-8086;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6969;KEGG: 00250+4.3.1.1;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913 "Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Alanine, aspartate and glutamate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)" EDAN003294-PA 4 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"Zeatin biosynthesis" EDAN019146-PA 3 KEGG: 00340+4.2.1.19;MetaCyc: PWY-7851;KEGG: 00770+2.7.7.3 "Histidine metabolism";"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" EDAN011669-PA 10 MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;Reactome: R-HSA-69205;Reactome: R-HSA-499943;KEGG: 00670+2.1.1.45 "Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"One carbon pool by folate" EDAN000172-PA 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214 "TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins" EDAN010050-PA 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" EDAN005084-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN012800-PA 8 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" EDAN000769-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" EDAN008885-PA 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" EDAN003271-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN004172-PA 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" EDAN013615-PA 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" EDAN002654-PA 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-114608 "Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation" EDAN015190-PA 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" EDAN006232-PA 11 Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418594 "Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events" EDAN011400-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN013580-PA 13 Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-8948216 "ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"NCAM1 interactions";"Collagen degradation";"Signaling by PDGF";"Integrin cell surface interactions";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen chain trimerization" EDAN011935-PA 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" EDAN012585-PA 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833 "ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)" EDAN005792-PA 2 MetaCyc: PWY-7380;KEGG: 00780+6.3.3.3 "Biotin biosynthesis from 8-amino-7-oxononanoate II";"Biotin metabolism" EDAN009340-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN007969-PA 33 Reactome: R-HSA-5673001;Reactome: R-HSA-2871809;Reactome: R-HSA-2730905;Reactome: R-HSA-1236382;Reactome: R-HSA-8983432;Reactome: R-HSA-5637810;Reactome: R-HSA-5654688;Reactome: R-HSA-9026519;Reactome: R-HSA-2424491;Reactome: R-HSA-167044;Reactome: R-HSA-210993;Reactome: R-HSA-354192;Reactome: R-HSA-9027284;Reactome: R-HSA-9664565;Reactome: R-HSA-381038;Reactome: R-HSA-512988;Reactome: R-HSA-5654699;Reactome: R-HSA-9020558;Reactome: R-HSA-9009391;Reactome: R-HSA-5654704;Reactome: R-HSA-1250347;Reactome: R-HSA-2428933;Reactome: R-HSA-180336;Reactome: R-HSA-9634285;Reactome: R-HSA-5654719;Reactome: R-HSA-8851805;Reactome: R-HSA-912526;Reactome: R-HSA-74751;Reactome: R-HSA-8853659;Reactome: R-HSA-9034864;Reactome: R-HSA-74749;Reactome: R-HSA-1250196;Reactome: R-HSA-2871796 "RAF/MAP kinase cascade";"FCERI mediated Ca+2 mobilization";"Role of LAT2/NTAL/LAB on calcium mobilization";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Interleukin-15 signaling";"Constitutive Signaling by EGFRvIII";"SHC-mediated cascade:FGFR1";"Activated NTRK2 signals through RAS";"DAP12 signaling";"Signalling to RAS";"Tie2 Signaling";"Integrin signaling";"Erythropoietin activates RAS";"Signaling by ERBB2 KD Mutants";"XBP1(S) activates chaperone genes";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR2";"Interleukin-2 signaling";"Extra-nuclear estrogen signaling";"SHC-mediated cascade:FGFR3";"SHC1 events in ERBB4 signaling";"SHC-related events triggered by IGF1R";"SHC1 events in EGFR signaling";"Constitutive Signaling by Overexpressed ERBB2";"SHC-mediated cascade:FGFR4";"MET activates RAS signaling";"Interleukin receptor SHC signaling";"Insulin receptor signalling cascade";"RET signaling";"Activated NTRK3 signals through RAS";"Signal attenuation";"SHC1 events in ERBB2 signaling";"FCERI mediated MAPK activation" EDAN012737-PA 4 Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356 "Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" EDAN014512-PA 8 Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-432720 "WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis" EDAN002400-PA 1 Reactome: R-HSA-1221632 "Meiotic synapsis" EDAN011604-PA 29 Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-112382 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex" EDAN012156-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN018781-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN012121-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" EDAN005591-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN000017-PA 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" EDAN003853-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" EDAN009321-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN011190-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" EDAN004593-PA 14 MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" EDAN014051-PA 5 Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" EDAN000578-PA 3 Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70895 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism" EDAN012840-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN016233-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" EDAN002144-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" EDAN003020-PA 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" EDAN010155-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN018637-PA 5 Reactome: R-HSA-3371453;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;Reactome: R-HSA-1362409 "Regulation of HSF1-mediated heat shock response";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" EDAN003950-PA 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes" EDAN003287-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN015319-PA 16 Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-2559585 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence" EDAN001589-PA 1 Reactome: R-HSA-70921 "Histidine catabolism" EDAN001151-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN011728-PA 9 MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-8004 "Glycerol degradation to butanol";"Glycolysis";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Entner-Doudoroff pathway I" EDAN006607-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" EDAN002992-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN002543-PA 10 Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473 "SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint" EDAN012557-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN000598-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane" EDAN010863-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" EDAN000873-PA 11 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance" EDAN003202-PA 5 KEGG: 00550+2.5.1.7;KEGG: 00520+2.5.1.7;MetaCyc: PWY-6386;MetaCyc: PWY-6387;MetaCyc: PWY-7953 "Peptidoglycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)" EDAN009016-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN014895-PA 7 MetaCyc: PWY-7886;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483191 "Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PC" EDAN018035-PA 8 Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27 "Pyruvate metabolism";"Propanoate metabolism";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism" EDAN008276-PA 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" EDAN002277-PA 4 Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" EDAN003282-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" EDAN003278-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN001735-PA 1 Reactome: R-HSA-3295583 "TRP channels" EDAN014046-PA 15 Reactome: R-HSA-186763;Reactome: R-HSA-1170546;Reactome: R-HSA-8985947;Reactome: R-HSA-1433557;Reactome: R-HSA-1839117;Reactome: R-HSA-9020958;Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-9020558;Reactome: R-HSA-9027283;Reactome: R-HSA-8983432;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-9645135;Reactome: R-HSA-8854691 "Downstream signal transduction";"Prolactin receptor signaling";"Interleukin-9 signaling";"Signaling by SCF-KIT";"Signaling by cytosolic FGFR1 fusion mutants";"Interleukin-21 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"Interleukin-2 signaling";"Erythropoietin activates STAT5";"Interleukin-15 signaling";"Signaling by Leptin";"Growth hormone receptor signaling";"STAT5 Activation";"Interleukin-20 family signaling" EDAN000127-PA 2 KEGG: 00410+6.3.2.1;KEGG: 00770+6.3.2.1 "beta-Alanine metabolism";"Pantothenate and CoA biosynthesis" EDAN010152-PA 18 Reactome: R-HSA-69656;Reactome: R-HSA-69563;Reactome: R-HSA-8941855;Reactome: R-HSA-6785807;Reactome: R-HSA-6804116;Reactome: R-HSA-9617828;Reactome: R-HSA-8852276;Reactome: R-HSA-198323;Reactome: R-HSA-69231;Reactome: R-HSA-8878166;Reactome: R-HSA-5674400;Reactome: R-HSA-9616222;Reactome: R-HSA-69202;Reactome: R-HSA-8866911;Reactome: R-HSA-2559586;Reactome: R-HSA-187577;Reactome: R-HSA-69895;Reactome: R-HSA-2559582 "Cyclin A:Cdk2-associated events at S phase entry";"p53-Dependent G1 DNA Damage Response";"RUNX3 regulates CDKN1A transcription";"Interleukin-4 and Interleukin-13 signaling";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest";"FOXO-mediated transcription of cell cycle genes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AKT phosphorylates targets in the cytosol";"Cyclin D associated events in G1";"Transcriptional regulation by RUNX2";"Constitutive Signaling by AKT1 E17K in Cancer";"Transcriptional regulation of granulopoiesis";"Cyclin E associated events during G1/S transition";"TFAP2 (AP-2) family regulates transcription of cell cycle factors";"DNA Damage/Telomere Stress Induced Senescence";"SCF(Skp2)-mediated degradation of p27/p21";"Transcriptional activation of cell cycle inhibitor p21";"Senescence-Associated Secretory Phenotype (SASP)" EDAN001637-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN002155-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN016331-PA 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" EDAN018841-PA 4 KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686 "Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I" EDAN003670-PA 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" EDAN005741-PA 4 Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN011844-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN008544-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN000174-PA 2 MetaCyc: PWY-5154;KEGG: 00220+2.3.1.35+2.3.1.1 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis" EDAN011689-PA 8 MetaCyc: PWY-5789;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation" EDAN000687-PA 4 MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722 "Choline degradation IV";"Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)" EDAN000649-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" EDAN000561-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN006042-PA 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" EDAN000057-PA 3 MetaCyc: PWY-6871;KEGG: 00290+2.3.3.13;KEGG: 00620+2.3.3.13 "3-methylbutanol biosynthesis (engineered)";"Valine, leucine and isoleucine biosynthesis";"Pyruvate metabolism" EDAN009585-PA 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" EDAN011984-PA 13 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Signaling downstream of RAS mutants";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Thermogenesis";"Signaling by BRAF and RAF fusions";"Relaxin signaling pathway";"Human papillomavirus infection" EDAN005641-PA 21 MetaCyc: PWY-7657;MetaCyc: PWY-7688;MetaCyc: PWY-6973;MetaCyc: PWY-7315;KEGG: 00521+4.2.1.46;MetaCyc: PWY-7316;MetaCyc: PWY-7440;MetaCyc: PWY-7814;MetaCyc: PWY-7104;MetaCyc: PWY-7301;MetaCyc: PWY-7318;KEGG: 00525+4.2.1.46;MetaCyc: PWY-7413;MetaCyc: PWY-7312;MetaCyc: PWY-6976;KEGG: 00523+4.2.1.46;MetaCyc: PWY-7414;MetaCyc: PWY-6953;MetaCyc: PWY-6942;MetaCyc: PWY-6974;MetaCyc: PWY-6808 "Dtdp-beta-l-digitoxose biosynthesis";"Dtdp-d-ravidosamine and dTDP-4-acetyl-D-ravidosamine biosynthesis";"Dtdp-d-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis";"Dtdp-n-acetylthomosamine biosynthesis";"Streptomycin biosynthesis";"Dtdp-n-acetylviosamine biosynthesis";"Dtdp-beta-l-4-epi-vancosamine biosynthesis";"Dtdp-l-daunosamine biosynthesis";"Dtdp-l-megosamine biosynthesis";"Dtdp-4-o-demethyl-beta-l-noviose biosynthesis";"Dtdp-3-acetamido-3,6-dideoxy-alpha-d-glucose biosynthesis";"Acarbose and validamycin biosynthesis";"Dtdp-6-deoxy-alpha-d-allose biosynthesis";"Dtdp-d-beta-fucofuranose biosynthesis";"Dtdp-l-mycarose biosynthesis";"Polyketide sugar unit biosynthesis";"Dtdp-alpha-d-mycaminose biosynthesis";"Dtdp-3-acetamido-alpha-d-fucose biosynthesis";"Dtdp-d-desosamine biosynthesis";"Dtdp-l-olivose biosynthesis";"Dtdp-d-forosamine biosynthesis" EDAN010107-PA 27 Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4615885 "ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins" EDAN018955-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" EDAN000570-PA 5 KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00340+4.3.2.10;KEGG: 00250+3.5.1.2 "D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Histidine metabolism";"Alanine, aspartate and glutamate metabolism" EDAN002631-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN004400-PA 9 Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-9617828 "Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"FOXO-mediated transcription of cell cycle genes" EDAN001925-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN002655-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN016874-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN006215-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN011601-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN009256-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN012967-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN015113-PA 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" EDAN017703-PA 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" EDAN005292-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" EDAN018125-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" EDAN007676-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" EDAN014073-PA 4 KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III" EDAN005122-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" EDAN010692-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN016908-PA 10 Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" EDAN003388-PA 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" EDAN014093-PA 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" EDAN005572-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" EDAN012731-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN010894-PA 16 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" EDAN015723-PA 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" EDAN005982-PA 5 MetaCyc: PWY-5188;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" EDAN008262-PA 18 Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-72086 "TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"mRNA Capping" EDAN004291-PA 14 Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Intraflagellar transport";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Macroautophagy";"Separation of Sister Chromatids" EDAN013898-PA 33 Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159236 "Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN011287-PA 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" EDAN019310-PA 4 Reactome: R-HSA-3359478;Reactome: R-HSA-71032;Reactome: R-HSA-196741;Reactome: R-HSA-3359475 "Defective MUT causes methylmalonic aciduria mut type";"Propionyl-CoA catabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAA causes methylmalonic aciduria type cblA" EDAN003428-PA 6 MetaCyc: PWY-6167;KEGG: 00195+7.1.2.2;KEGG: 00740+2.5.1.9;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;MetaCyc: PWY-6168 "Flavin biosynthesis II (archaea)";"Photosynthesis";"Riboflavin metabolism";"Oxidative phosphorylation";"ATP biosynthesis";"Flavin biosynthesis III (fungi)" EDAN001616-PA 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" EDAN007486-PA 1 Reactome: R-HSA-8949613 "Cristae formation" EDAN000573-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN002357-PA 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" EDAN001252-PA 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" EDAN003431-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN011198-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" EDAN011923-PA 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" EDAN008776-PA 27 Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-1169408 "SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism" EDAN007872-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" EDAN013624-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN003321-PA 4 MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040 "Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis" EDAN013733-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" EDAN018346-PA 2 MetaCyc: PWY-6163;KEGG: 00400+4.2.3.5 "Chorismate biosynthesis from 3-dehydroquinate";"Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN017579-PA 11 MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism" EDAN008192-PA 20 MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6 "10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism" EDAN002334-PA 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" EDAN011364-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN005338-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" EDAN005769-PA 4 MetaCyc: PWY-7560;KEGG: 00900+4.6.1.12;KEGG: 00900+2.7.7.60;KEGG: 00900+4.6.1.12+2.7.7.60 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Terpenoid backbone biosynthesis";"Terpenoid backbone biosynthesis" EDAN018081-PA 1 KEGG: 00270+4.4.1.15 "Cysteine and methionine metabolism" EDAN007347-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN000083-PA 19 MetaCyc: PWY-5172;Reactome: R-HSA-6798695;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-163765;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913 "Acetyl-coa biosynthesis III (from citrate)";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)" EDAN016653-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN008431-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" EDAN007321-PA 6 Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" EDAN008772-PA 5 Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20 "Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis" EDAN008552-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN012470-PA 10 MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" EDAN007335-PA 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115 "Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" EDAN018484-PA 3 Reactome: R-HSA-71403;KEGG: 00430+1.4.1.1;KEGG: 00250+1.4.1.1 "Citric acid cycle (TCA cycle)";"Taurine and hypotaurine metabolism";"Alanine, aspartate and glutamate metabolism" EDAN016754-PA 7 KEGG: 00710+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11 "Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" EDAN000013-PA 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I" EDAN016442-PA 13 Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398 "Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Ca2+ pathway" EDAN012868-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN015450-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN008990-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN004431-PA 26 Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-389977;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Aggrephagy";"HCMV Early Events";"Post-chaperonin tubulin folding pathway";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN014882-PA 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway" EDAN012248-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN012608-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" EDAN018456-PA 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" EDAN009200-PA 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" EDAN017908-PA 4 Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" EDAN002738-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN003236-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN015175-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" EDAN009481-PA 11 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex" EDAN007879-PA 4 KEGG: 00340+3.5.2.7;MetaCyc: PWY-5028;Reactome: R-HSA-70921;MetaCyc: PWY-5030 "Histidine metabolism";"L-histidine degradation II";"Histidine catabolism";"L-histidine degradation III" EDAN011318-PA 18 MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482925 "Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG" EDAN005273-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" EDAN011863-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN000010-PA 2 Reactome: R-HSA-425561;Reactome: R-HSA-936837 "Sodium/Calcium exchangers";"Ion transport by P-type ATPases" EDAN010516-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" EDAN006835-PA 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" EDAN017343-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN015325-PA 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" EDAN015201-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN003465-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN015206-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN018802-PA 4 Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198 "Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis" EDAN015832-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN012775-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN010615-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" EDAN004962-PA 27 Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-191859 "SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly" EDAN010525-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN013162-PA 14 Reactome: R-HSA-166058;Reactome: R-HSA-5602498;Reactome: R-HSA-6798695;Reactome: R-HSA-1989781;Reactome: R-HSA-1236973;Reactome: R-HSA-6785807;Reactome: R-HSA-381340;Reactome: R-HSA-3000471;Reactome: R-HSA-168188;Reactome: R-HSA-114608;Reactome: R-HSA-434313;Reactome: R-HSA-5686938;Reactome: R-HSA-1236974;Reactome: R-HSA-5603041 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"Neutrophil degranulation";"PPARA activates gene expression";"Cross-presentation of particulate exogenous antigens (phagosomes)";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation of white adipocyte differentiation";"Scavenging by Class B Receptors";"Toll Like Receptor TLR6:TLR2 Cascade";"Platelet degranulation";"Intracellular metabolism of fatty acids regulates insulin secretion";"Regulation of TLR by endogenous ligand";"ER-Phagosome pathway";"IRAK4 deficiency (TLR2/4)" EDAN002302-PA 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" EDAN013782-PA 6 Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis" EDAN012114-PA 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" EDAN010165-PA 9 Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796 "GPVI-mediated activation cascade";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation" EDAN009960-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN003695-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN011339-PA 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" EDAN007247-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" EDAN003307-PA 6 KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00230+3.6.1.41;MetaCyc: PWY-6749;MetaCyc: PWY-8013 "Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Purine metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III" EDAN000439-PA 3 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" EDAN003987-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN015919-PA 13 MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1 "Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis" EDAN005687-PA 2 MetaCyc: PWY-6163;KEGG: 00400+2.7.1.71 "Chorismate biosynthesis from 3-dehydroquinate";"Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN011875-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" EDAN007161-PA 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" EDAN017837-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN011749-PA 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" EDAN019431-PA 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" EDAN008560-PA 3 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import" EDAN006080-PA 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" EDAN007326-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN011155-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN009404-PA 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" EDAN005086-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN005884-PA 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" EDAN004255-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN000078-PA 13 MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913 "Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)" EDAN007044-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN013293-PA 14 Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416 "Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" EDAN003989-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN018963-PA 5 KEGG: 00261+1.17.1.8;MetaCyc: PWY-2942;MetaCyc: PWY-2941;KEGG: 00300+1.17.1.8;MetaCyc: PWY-5097 "Monobactam biosynthesis";"L-lysine biosynthesis III";"L-lysine biosynthesis II";"Lysine biosynthesis";"L-lysine biosynthesis VI" EDAN008876-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" EDAN001763-PA 9 Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-975634 "Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport" EDAN001903-PA 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" EDAN018658-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN018799-PA 1 Reactome: R-HSA-186797 "Signaling by PDGF" EDAN015278-PA 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7 "Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism" EDAN002313-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" EDAN018661-PA 9 MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-5664 "Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" EDAN007085-PA 5 Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211976 "PPARA activates gene expression";"Phase I - Functionalization of compounds";"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Endogenous sterols" EDAN019245-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" EDAN007498-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN010464-PA 17 Reactome: R-HSA-3270619;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-1834949;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-912446 "IRF3-mediated induction of type I IFN";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cytosolic sensors of pathogen-associated DNA";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination" EDAN001815-PA 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN007283-PA 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" EDAN011393-PA 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" EDAN004109-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" EDAN014313-PA 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases" EDAN015767-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" EDAN004222-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN018811-PA 22 MetaCyc: PWY-622;Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-5054;MetaCyc: PWY-6981;MetaCyc: PWY-621;KEGG: 00520+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-7238;KEGG: 00500+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-3801;MetaCyc: PWY-5514;MetaCyc: PWY-5659;MetaCyc: PWY-7347;MetaCyc: PWY-5384;Reactome: R-HSA-5628897;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.9;Reactome: R-HSA-6798695;Reactome: R-HSA-70263 "Starch biosynthesis";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"D-sorbitol biosynthesis I";"Chitin biosynthesis";"Sucrose degradation III (sucrose invertase)";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"1,5-anhydrofructose degradation";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"GDP-mannose biosynthesis";"Sucrose biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"TP53 Regulates Metabolic Genes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Neutrophil degranulation";"Gluconeogenesis" EDAN006794-PA 1 Reactome: R-HSA-376172 "DSCAM interactions" EDAN015084-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN008893-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN013486-PA 11 Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206 "RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha" EDAN010904-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN008330-PA 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" EDAN008511-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN012199-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN016398-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" EDAN019514-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" EDAN007107-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN009929-PA 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" EDAN017626-PA 11 MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7560;MetaCyc: PWY-6859;MetaCyc: PWY-922;MetaCyc: PWY-7102;MetaCyc: PWY-5123;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6383 "Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Methylerythritol phosphate pathway II";"All-trans-farnesol biosynthesis";"Mevalonate pathway I";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" EDAN008166-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" EDAN014304-PA 9 Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68952 "Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Polymerase switching";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"DNA replication initiation" EDAN012042-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN018927-PA 6 MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism" EDAN009646-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN005809-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN004563-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN006411-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN000059-PA 11 KEGG: 00660+2.2.1.6;MetaCyc: PWY-7111;MetaCyc: PWY-6389;MetaCyc: PWY-5939;MetaCyc: PWY-5938;MetaCyc: PWY-5104;KEGG: 00770+2.2.1.6;KEGG: 00650+2.2.1.6;MetaCyc: PWY-5103;KEGG: 00290+2.2.1.6;MetaCyc: PWY-5101 "C5-Branched dibasic acid metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Pyruvate fermentation to (S)-acetoin";"Pyruvate fermentation to (R)-acetoin II";"Pyruvate fermentation to (R)-acetoin I";"L-isoleucine biosynthesis IV";"Pantothenate and CoA biosynthesis";"Butanoate metabolism";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II" EDAN006125-PA 16 Reactome: R-HSA-8964038;Reactome: R-HSA-196025;Reactome: R-HSA-164939;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-177504 "LDL clearance";"Formation of annular gap junctions";"Nef mediated downregulation of CD28 cell surface expression";"Recycling pathway of L1";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Retrograde neurotrophin signalling" EDAN008395-PA 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" EDAN007523-PA 6 Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001 "FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade" EDAN006054-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN011957-PA 1 Reactome: R-HSA-5617833 "Cilium Assembly" EDAN014912-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN001112-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" EDAN012636-PA 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" EDAN008005-PA 33 Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-191859;Reactome: R-HSA-3232142 "Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins" EDAN000104-PA 3 Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine" EDAN003891-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" EDAN018499-PA 1 KEGG: 00340+5.3.1.16 "Histidine metabolism" EDAN011949-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN009011-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN011656-PA 2 KEGG: 00130+4.1.3.36;MetaCyc: PWY-5837 "Ubiquinone and other terpenoid-quinone biosynthesis";"2-carboxy-1,4-naphthoquinol biosynthesis" EDAN010741-PA 5 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" EDAN016196-PA 5 Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN018048-PA 3 Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676 "Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle" EDAN013889-PA 12 Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-5362798;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-982772 "Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TNF signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Growth hormone receptor signaling" EDAN010382-PA 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" EDAN018336-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN018115-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" EDAN019368-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN018765-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN002410-PA 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" EDAN007501-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" EDAN012464-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN010231-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN002088-PA 3 Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511 "Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination" EDAN002368-PA 13 MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II" EDAN001990-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN012318-PA 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" EDAN004657-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" EDAN003140-PA 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" EDAN007073-PA 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" EDAN003464-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN000437-PA 3 MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" EDAN009064-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" EDAN014943-PA 6 Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187 "Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress" EDAN007621-PA 14 Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69091 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Polymerase switching" EDAN000140-PA 4 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)" EDAN003319-PA 6 MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2;Reactome: R-HSA-500753;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791 "UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"UMP biosynthesis III" EDAN016489-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" EDAN001816-PA 4 Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" EDAN010640-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN016741-PA 1 KEGG: 00970+6.1.1.15 "Aminoacyl-tRNA biosynthesis" EDAN011655-PA 12 MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-6969 "Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" EDAN010605-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN002980-PA 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" EDAN000008-PA 9 Reactome: R-HSA-611105;MetaCyc: PWY-1881;Reactome: R-HSA-6799198;MetaCyc: PWY-5497;Reactome: R-HSA-432047;MetaCyc: PWY-6696;KEGG: 00630+1.17.1.9;MetaCyc: PWY-7985;KEGG: 00680+1.17.1.9 "Respiratory electron transport";"Formate oxidation to CO2";"Complex I biogenesis";"Purine nucleobases degradation II (anaerobic)";"Passive transport by Aquaporins";"Oxalate degradation III";"Glyoxylate and dicarboxylate metabolism";"Oxalate degradation VI";"Methane metabolism" EDAN011273-PA 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" EDAN004471-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN019384-PA 13 MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538 "Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI" EDAN015986-PA 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" EDAN011682-PA 7 MetaCyc: PWY-6167;KEGG: 00790+3.5.4.25;KEGG: 00740+3.5.4.25;MetaCyc: PWY-7991;MetaCyc: PWY-7539;MetaCyc: PWY-6168;KEGG: 00740+4.1.99.12 "Flavin biosynthesis II (archaea)";"Folate biosynthesis";"Riboflavin metabolism";"Toxoflavin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism" EDAN011948-PA 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" EDAN006044-PA 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" EDAN011576-PA 1 Reactome: R-HSA-400253 "Circadian Clock" EDAN016050-PA 24 Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833 "Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Aggrephagy";"Cilium Assembly" EDAN001974-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN002446-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN009798-PA 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" EDAN002156-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN016736-PA 8 Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987 "Biotin transport and metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" EDAN009008-PA 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" EDAN001286-PA 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" EDAN006306-PA 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" EDAN010358-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN010804-PA 5 KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68 "Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis" EDAN003886-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" EDAN000100-PA 11 KEGG: 00550+2.4.1.129;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-5265;Reactome: R-HSA-4549356;Reactome: R-HSA-196757;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00550+2.7.8.13;KEGG: 00550+2.4.1.227 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Metabolism of folate and pterines";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis" EDAN008295-PA 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" EDAN008625-PA 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" EDAN005945-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN014162-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN007430-PA 7 Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724 "PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription" EDAN014486-PA 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1" EDAN003460-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN005789-PA 8 MetaCyc: PWY-5747;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00640+4.2.1.99;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403 "2-methylcitrate cycle II";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)" EDAN014541-PA 6 KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5497;Reactome: R-HSA-70921;MetaCyc: PWY-5030;KEGG: 00670+2.1.2.5;KEGG: 00340+2.1.2.5 "One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Histidine catabolism";"L-histidine degradation III";"One carbon pool by folate";"Histidine metabolism" EDAN007530-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN000851-PA 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" EDAN003593-PA 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN008610-PA 5 Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-983168;Reactome: R-HSA-5205685 "Amyloid fiber formation";"Josephin domain DUBs";"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy" EDAN000260-PA 2 Reactome: R-HSA-6793080;KEGG: 00970+6.1.1.16 "rRNA modification in the mitochondrion";"Aminoacyl-tRNA biosynthesis" EDAN012030-PA 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" EDAN018513-PA 6 KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52 "Methane metabolism";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Cysteine and methionine metabolism" EDAN014972-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" EDAN000605-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN012451-PA 10 MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-6901 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"Superpathway of glucose and xylose degradation" EDAN019110-PA 10 Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-9022692 "Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity" EDAN010938-PA 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" EDAN017830-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN017133-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN013721-PA 3 Reactome: R-HSA-6783310;Reactome: R-HSA-606279;Reactome: R-HSA-5620922 "Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere";"BBSome-mediated cargo-targeting to cilium" EDAN007935-PA 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" EDAN003513-PA 18 Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051 "Acyl chain remodelling of PS";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Ether lipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I" EDAN018632-PA 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" EDAN000501-PA 4 Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" EDAN006011-PA 14 Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" EDAN013066-PA 13 MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine metabolism" EDAN012034-PA 3 Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193 "Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" EDAN013502-PA 7 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA" EDAN007047-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN009982-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" EDAN010926-PA 4 KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)" EDAN004413-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN008619-PA 5 MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527 "D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" EDAN010833-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" EDAN008617-PA 9 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"Neutrophil degranulation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy" EDAN005429-PA 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" EDAN014660-PA 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" EDAN005787-PA 7 KEGG: 00720+2.7.9.1;MetaCyc: PWY-6549;KEGG: 00620+2.7.9.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00710+2.7.9.1;MetaCyc: PWY-241 "Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" EDAN009700-PA 5 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination" EDAN011894-PA 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811434 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN014949-PA 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" EDAN019278-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" EDAN011661-PA 8 MetaCyc: PWY-7560;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00010+1.2.4.1;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892 "Methylerythritol phosphate pathway II";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Glycolysis / Gluconeogenesis";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)" EDAN010129-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN015546-PA 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" EDAN008583-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN011213-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN001120-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN016004-PA 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" EDAN008361-PA 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" EDAN008717-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN011299-PA 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" EDAN013098-PA 8 Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-182218 "Ion channel transport";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Nef Mediated CD8 Down-regulation" EDAN008077-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" EDAN012549-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" EDAN003369-PA 9 MetaCyc: PWY-6385;KEGG: 00550+2.4.1.129;Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-6470;Reactome: R-HSA-196757;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227 "Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Metabolism of folate and pterines";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis" EDAN001546-PA 4 Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-373753 "Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions" EDAN004901-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" EDAN011837-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-5678771;Reactome: R-HSA-382556 "PPARA activates gene expression";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"ABC-family proteins mediated transport" EDAN005951-PA 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" EDAN015535-PA 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" EDAN004069-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" EDAN018384-PA 7 MetaCyc: PWY-5154;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism" EDAN006214-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN018949-PA 15 MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7383 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)" EDAN006599-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN014516-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" EDAN016329-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN007140-PA 2 Reactome: R-HSA-111469;Reactome: R-HSA-111457 "SMAC, XIAP-regulated apoptotic response";"Release of apoptotic factors from the mitochondria" EDAN004540-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN006818-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN011897-PA 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" EDAN019357-PA 3 MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)" EDAN012240-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN013142-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN005606-PA 6 Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.10 "Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism" EDAN006804-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" EDAN007926-PA 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" EDAN015801-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" EDAN008675-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN009669-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" EDAN011355-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN008844-PA 7 MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7586 "GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" EDAN007622-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN000079-PA 14 Reactome: R-HSA-611105;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913 "Respiratory electron transport";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)" EDAN019080-PA 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" EDAN014411-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" EDAN002454-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN012686-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" EDAN005806-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" EDAN003377-PA 4 MetaCyc: PWY-7250;Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism" EDAN018182-PA 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" EDAN014013-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" EDAN007934-PA 14 MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" EDAN002629-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN008902-PA 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" EDAN001606-PA 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" EDAN019572-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN004107-PA 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632 "Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" EDAN005403-PA 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" EDAN016693-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" EDAN010025-PA 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" EDAN008293-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" EDAN007697-PA 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" EDAN018644-PA 1 KEGG: 00970+6.1.1.5 "Aminoacyl-tRNA biosynthesis" EDAN013760-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" EDAN000615-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN005734-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" EDAN004164-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN010810-PA 24 Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-9609690 "RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Cilium Assembly";"Aggrephagy";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HCMV Early Events" EDAN018335-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN005068-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870 "Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins" EDAN005169-PA 11 Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" EDAN011141-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" EDAN000327-PA 4 Reactome: R-HSA-5362517;Reactome: R-HSA-70895;Reactome: R-HSA-204174;Reactome: R-HSA-1296072 "Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Voltage gated Potassium channels" EDAN014236-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN003196-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN003422-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" EDAN010584-PA 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" EDAN009913-PA 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" EDAN017936-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN006462-PA 3 Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105 "Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation" EDAN019167-PA 24 Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G alpha (s) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" EDAN004574-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN016824-PA 13 KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism" EDAN015150-PA 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" EDAN008309-PA 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" EDAN005348-PA 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" EDAN018719-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" EDAN002500-PA 29 Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-3371453;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696395;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942 "PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Regulation of HSF1-mediated heat shock response";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Meiotic recombination";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)" EDAN017198-PA 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" EDAN000273-PA 4 Reactome: R-HSA-204174;Reactome: R-HSA-1296072;Reactome: R-HSA-70895;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Voltage gated Potassium channels";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid" EDAN004130-PA 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" EDAN019414-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN012610-PA 4 KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" EDAN000366-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN000304-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN019342-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN008904-PA 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" EDAN018601-PA 1 Reactome: R-HSA-196757 "Metabolism of folate and pterines" EDAN010937-PA 4 Reactome: R-HSA-194840;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "Rho GTPase cycle";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" EDAN015640-PA 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" EDAN010359-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN008234-PA 7 Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-5620922 "Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium" EDAN002214-PA 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" EDAN018892-PA 12 KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4 "Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen degradation";"Ether lipid metabolism" EDAN003551-PA 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" EDAN012216-PA 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" EDAN011723-PA 6 MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13 "5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism";"Purine metabolism" EDAN005709-PA 2 Reactome: R-HSA-5368286;KEGG: 00970+6.1.1.3 "Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis" EDAN006753-PA 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" EDAN011832-PA 4 Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-176187 "Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress" EDAN011611-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN002864-PA 11 Reactome: R-HSA-2029485;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4 "Role of phospholipids in phagocytosis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism" EDAN004217-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" EDAN006466-PA 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" EDAN011333-PA 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" EDAN008165-PA 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831 "ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" EDAN000093-PA 6 MetaCyc: PWY-8049;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-8047;KEGG: 00061+2.3.1.39 "Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis" EDAN001652-PA 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" EDAN003882-PA 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" EDAN003480-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN007803-PA 10 Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" EDAN015641-PA 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" EDAN017410-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" EDAN003166-PA 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis" EDAN007862-PA 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" EDAN016732-PA 7 Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039 "Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" EDAN011052-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN013907-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" EDAN006174-PA 4 KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis" EDAN011589-PA 3 Reactome: R-HSA-975871;Reactome: R-HSA-5603037;Reactome: R-HSA-168142 "MyD88 cascade initiated on plasma membrane";"IRAK4 deficiency (TLR5)";"Toll Like Receptor 10 (TLR10) Cascade" EDAN005670-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN000782-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN007227-PA 7 MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824 "Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis" EDAN000220-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN000504-PA 8 MetaCyc: PWY-7357;MetaCyc: PWY-7356;KEGG: 00730+2.5.1.3;MetaCyc: PWY-6907;MetaCyc: PWY-6908;MetaCyc: PWY-6894;MetaCyc: PWY-6893;MetaCyc: PWY-6897 "Thiamine formation from pyrithiamine and oxythiamine (yeast)";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis I (E. coli)";"Thiamine diphosphate biosynthesis II (Bacillus)";"Thiamine salvage II" EDAN001634-PA 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" EDAN005125-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN011016-PA 10 MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001 "Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" EDAN000298-PA 7 KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-1722 "One carbon pool by folate";"Folate transformations II (plants)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate" EDAN003630-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN012743-PA 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" EDAN009484-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN015664-PA 5 Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" EDAN005253-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" EDAN007972-PA 1 Reactome: R-HSA-1483255 "PI Metabolism" EDAN002867-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" EDAN009598-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" EDAN018440-PA 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" EDAN008694-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN001251-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN004992-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" EDAN006030-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" EDAN019153-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN006964-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" EDAN004001-PA 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" EDAN011479-PA 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" EDAN001611-PA 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1 "Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism" EDAN003158-PA 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" EDAN018253-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN004536-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN008814-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN019362-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN005994-PA 52 Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-5578749;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-77075;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-73780;Reactome: R-HSA-76071 "Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" EDAN000183-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" EDAN015897-PA 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism" EDAN000269-PA 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" EDAN007950-PA 33 KEGG: 00830+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-6333;KEGG: 00982+1.1.1.1;KEGG: 00680+1.1.1.284;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6313;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-7111;Reactome: R-HSA-71384;MetaCyc: PWY-7118;MetaCyc: PWY-7396;MetaCyc: PWY-7798;MetaCyc: PWY-6587;KEGG: 00592+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-7013;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5076;MetaCyc: PWY-1801;MetaCyc: PWY-5078;MetaCyc: PWY-6342;MetaCyc: PWY-5486;MetaCyc: PWY-3162;MetaCyc: PWY-6871;KEGG: 00626+1.1.1.1 "Retinol metabolism";"Salidroside biosynthesis";"Acetaldehyde biosynthesis I";"Drug metabolism - cytochrome P450";"Methane metabolism";"Tyrosine metabolism";"L-valine degradation II";"Glycolysis / Gluconeogenesis";"Serotonin degradation";"Fatty acid degradation";"L-methionine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Ethanol oxidation";"Chitin degradation to ethanol";"Butanol and isobutanol biosynthesis (engineered)";"Protein S-nitrosylation and denitrosylation";"Pyruvate fermentation to ethanol III";"alpha-Linolenic acid metabolism";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to ethanol I";"(S)-propane-1,2-diol degradation";"Metabolism of xenobiotics by cytochrome P450";"L-phenylalanine degradation III";"Chloroalkane and chloroalkene degradation";"Phenylethanol biosynthesis";"L-leucine degradation III";"Formaldehyde oxidation II (glutathione-dependent)";"L-isoleucine degradation II";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol II";"L-tryptophan degradation V (side chain pathway)";"3-methylbutanol biosynthesis (engineered)";"Naphthalene degradation" EDAN012368-PA 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228 "Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix" EDAN000413-PA 5 MetaCyc: PWY-7176;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;Reactome: R-HSA-499943 "UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates" EDAN000092-PA 23 Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWYG-321;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;Reactome: R-HSA-6799198;MetaCyc: PWY-5973;Reactome: R-HSA-389661;Reactome: R-HSA-77289;KEGG: 00061+1.1.1.100;MetaCyc: PWY-6282;MetaCyc: PWY-7664;MetaCyc: PWY-7858;MetaCyc: PWY-5971;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-7663;KEGG: 00780+1.1.1.100;MetaCyc: PWY-5367;MetaCyc: PWY-6519;Reactome: R-HSA-611105 "Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Complex I biogenesis";"Cis-vaccenate biosynthesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Fatty acid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"Petroselinate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Respiratory electron transport" EDAN004686-PA 14 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-7416 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)" EDAN006059-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" EDAN003602-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN005559-PA 4 KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841 "Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" EDAN015067-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN014951-PA 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" EDAN015183-PA 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination" EDAN008646-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN019318-PA 14 MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5723 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Rubisco shunt" EDAN002299-PA 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" EDAN000203-PA 7 MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363 "Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation" EDAN004273-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN006351-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" EDAN015001-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN015102-PA 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825 "Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis" EDAN019479-PA 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" EDAN008713-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN005762-PA 2 Reactome: R-HSA-196741;Reactome: R-HSA-4615885 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"SUMOylation of DNA replication proteins" EDAN001308-PA 3 Reactome: R-HSA-983168;Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway";"Protein ubiquitination" EDAN006919-PA 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" EDAN004617-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN017490-PA 4 Reactome: R-HSA-2029482;Reactome: R-HSA-8849471;Reactome: R-HSA-164944;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Nef and signal transduction";"VEGFA-VEGFR2 Pathway" EDAN010901-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN011284-PA 12 Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Rho GTPase cycle";"Human papillomavirus infection";"NRAGE signals death through JNK";"Relaxin signaling pathway";"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway" EDAN011385-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN019399-PA 6 MetaCyc: PWY-5316;MetaCyc: PWY-7342;Reactome: R-HSA-611105;KEGG: 00760+1.4.3.16;Reactome: R-HSA-71403;KEGG: 00250+1.4.3.16 "Nicotine biosynthesis";"Superpathway of nicotine biosynthesis";"Respiratory electron transport";"Nicotinate and nicotinamide metabolism";"Citric acid cycle (TCA cycle)";"Alanine, aspartate and glutamate metabolism" EDAN000056-PA 4 KEGG: 00660+1.1.1.85;KEGG: 00290+1.1.1.85;MetaCyc: PWY-7396;Reactome: R-HSA-71403 "C5-Branched dibasic acid metabolism";"Valine, leucine and isoleucine biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"Citric acid cycle (TCA cycle)" EDAN015167-PA 20 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-5696397 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER" EDAN017968-PA 9 Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237 "HS-GAG biosynthesis";"HS-GAG degradation";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2" EDAN014112-PA 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" EDAN009482-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN012719-PA 29 Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167158 "Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex" EDAN016457-PA 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" EDAN017917-PA 13 MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5 "Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism" EDAN017573-PA 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" EDAN010339-PA 9 KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780 "Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism" EDAN017604-PA 1 Reactome: R-HSA-977225 "Amyloid fiber formation" EDAN018343-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN016365-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN016666-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN006443-PA 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" EDAN018223-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" EDAN003292-PA 3 MetaCyc: PWY-1269;KEGG: 00540+3.1.3.45;MetaCyc: PWY-7674 "CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis";"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis" EDAN008300-PA 7 KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517 "Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid" EDAN013535-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" EDAN010706-PA 1 Reactome: R-HSA-400253 "Circadian Clock" EDAN012720-PA 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" EDAN002276-PA 5 Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" EDAN008614-PA 5 MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336 "2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation";"Pentose phosphate pathway";"Pentose phosphate pathway" EDAN015777-PA 5 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)" EDAN005452-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN010082-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" EDAN012298-PA 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" EDAN017345-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" EDAN001470-PA 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" EDAN014178-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN002808-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN008762-PA 10 Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-2160916 "Neutrophil degranulation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation" EDAN005334-PA 5 Reactome: R-HSA-9609523;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-5694530;Reactome: R-HSA-6807878 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"Cargo concentration in the ER";"COPI-mediated anterograde transport" EDAN013052-PA 5 MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234 "Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III" EDAN003215-PA 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" EDAN002649-PA 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14 "Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation" EDAN018700-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" EDAN010500-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN019012-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN009544-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN005706-PA 4 Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2 "Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism" EDAN000447-PA 26 Reactome: R-HSA-1799339;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;Reactome: R-HSA-975956;MetaCyc: PWY-5695;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;MetaCyc: PWY-6596;Reactome: R-HSA-156827;KEGG: 00230+6.3.5.2;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6798695;Reactome: R-HSA-379726;Reactome: R-HSA-73817;Reactome: R-HSA-9010553;KEGG: 00983+6.3.5.2;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;KEGG: 00983+1.1.1.205;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Inosine 5'-phosphate degradation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Adenosine nucleotides degradation I";"L13a-mediated translational silencing of Ceruloplasmin expression";"Purine metabolism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Neutrophil degranulation";"Mitochondrial tRNA aminoacylation";"Purine ribonucleoside monophosphate biosynthesis";"Regulation of expression of SLITs and ROBOs";"Drug metabolism - other enzymes";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Drug metabolism - other enzymes";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" EDAN019050-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN012844-PA 8 Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-2559580 "PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence" EDAN003405-PA 3 KEGG: 00620+2.3.3.13;MetaCyc: PWY-6871;KEGG: 00290+2.3.3.13 "Pyruvate metabolism";"3-methylbutanol biosynthesis (engineered)";"Valine, leucine and isoleucine biosynthesis" EDAN004469-PA 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion" EDAN006826-PA 5 Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" EDAN009525-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN009873-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN018991-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN015184-PA 3 Reactome: R-HSA-3214841;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "PKMTs methylate histone lysines";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN010756-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" EDAN008346-PA 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" EDAN006326-PA 5 KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway" EDAN017610-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN017560-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN004349-PA 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" EDAN019317-PA 6 KEGG: 00520+2.7.7.13;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;KEGG: 00051+2.7.7.13;MetaCyc: PWY-882 "Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)" EDAN006210-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" EDAN006079-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN010288-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" EDAN002716-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" EDAN013738-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN015899-PA 56 Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408 "Regulation of RAS by GAPs";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Hedgehog 'on' state";"Degradation of AXIN";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA" EDAN011953-PA 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" EDAN002799-PA 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" EDAN006473-PA 4 Reactome: R-HSA-8866427;Reactome: R-HSA-9031525;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN014278-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" EDAN004714-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" EDAN005588-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN005564-PA 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" EDAN003634-PA 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" EDAN012103-PA 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" EDAN013290-PA 14 MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417 "Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)" EDAN007224-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN015555-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN005651-PA 4 Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807 "Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III" EDAN003242-PA 5 Reactome: R-HSA-189451;MetaCyc: PWY-7159;MetaCyc: PWY-7766;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism" EDAN005919-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN016132-PA 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" EDAN004805-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN007086-PA 5 Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211976 "PPARA activates gene expression";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Endogenous sterols" EDAN015845-PA 27 Reactome: R-HSA-72187;Reactome: R-HSA-159227;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-111367;Reactome: R-HSA-159236;Reactome: R-HSA-72203;Reactome: R-HSA-975956;Reactome: R-HSA-191859;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-77588;Reactome: R-HSA-9010553;Reactome: R-HSA-167242;Reactome: R-HSA-159230;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-975957;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-6803529 "mRNA 3'-end processing";"Transport of the SLBP independent Mature mRNA";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"snRNP Assembly";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP Dependant Mature mRNA";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing" EDAN002930-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN000813-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" EDAN009272-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN003266-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN015056-PA 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" EDAN006373-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" EDAN004562-PA 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" EDAN002591-PA 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" EDAN006743-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" EDAN014316-PA 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" EDAN019323-PA 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" EDAN009911-PA 4 Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168 "Neutrophil degranulation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN000095-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN018948-PA 10 MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism" EDAN008674-PA 22 MetaCyc: PWY-6958;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-5080;MetaCyc: PWY-7053;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7606;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-7725 "Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)" EDAN012714-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" EDAN006657-PA 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" EDAN006966-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" EDAN001771-PA 11 KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-6549;Reactome: R-HSA-71403 "Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)" EDAN003477-PA 1 Reactome: R-HSA-200425 "Carnitine metabolism" EDAN014896-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" EDAN012164-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006052-PA 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" EDAN014060-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN003584-PA 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" EDAN003201-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN018209-PA 2 Reactome: R-HSA-5368286;KEGG: 00970+6.1.1.3 "Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis" EDAN006568-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" EDAN000213-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN012108-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN014835-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN010117-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" EDAN012019-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN005938-PA 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" EDAN009740-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" EDAN001829-PA 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" EDAN001702-PA 2 KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697 "Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)" EDAN019542-PA 5 Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" EDAN016176-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" EDAN013112-PA 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" EDAN007975-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" EDAN016969-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" EDAN011367-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN007938-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" EDAN001924-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN019423-PA 8 MetaCyc: PWY-5;MetaCyc: PWY-7400;Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4983;MetaCyc: PWY-5154 "Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Arginine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)" EDAN001121-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN016246-PA 17 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" EDAN019283-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" EDAN000608-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" EDAN015128-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN018543-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN005803-PA 13 MetaCyc: PWY-7858;KEGG: 00061+4.2.1.59;MetaCyc: PWY-7664;MetaCyc: PWY-7663;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWYG-321;KEGG: 00780+4.2.1.59;MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-6282 "(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"";"Biotin metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)" EDAN011658-PA 1 Reactome: R-HSA-196780 "Biotin transport and metabolism" EDAN017832-PA 19 Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-3299685;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-5628897;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;KEGG: 00480+1.11.1.15 "Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Detoxification of Reactive Oxygen Species";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"TP53 Regulates Metabolic Genes";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Glutathione metabolism" EDAN018666-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN015484-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN002443-PA 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" EDAN015156-PA 8 MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;Reactome: R-HSA-1483148;MetaCyc: PWY-7817 "Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)" EDAN004622-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN012125-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" EDAN012126-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" EDAN019306-PA 14 Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801 "HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Polymerase switching";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair" EDAN006852-PA 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" EDAN016617-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN015345-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN003337-PA 5 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;KEGG: 00790+2.10.1.1;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" EDAN000039-PA 10 KEGG: 00562+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5484 "Inositol phosphate metabolism";"Glycolysis";"Glycerol degradation to butanol";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)" EDAN011943-PA 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" EDAN000136-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN003580-PA 1 Reactome: R-HSA-203615 "eNOS activation" EDAN018472-PA 7 MetaCyc: PWY-5154;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III";"UMP biosynthesis I";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism" EDAN015157-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" EDAN015946-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN000710-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN000852-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" EDAN008302-PA 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" EDAN015907-PA 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" EDAN018874-PA 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" EDAN016831-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN005924-PA 2 Reactome: R-HSA-392154;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes" EDAN003328-PA 3 MetaCyc: PWY-7639;MetaCyc: PWY-5964;KEGG: 00790+2.7.7.77 "Bis(guanylyl molybdenum cofactor) biosynthesis";"Guanylyl molybdenum cofactor biosynthesis";"Folate biosynthesis" EDAN011907-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN011554-PA 17 MetaCyc: PWY-6608;MetaCyc: PWY-6644;MetaCyc: PWY-5695;MetaCyc: PWY-4202;MetaCyc: PWY-6611;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-7179;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-5532;Reactome: R-HSA-6798695 "Guanosine nucleotides degradation III";"Fluoroacetate and fluorothreonine biosynthesis";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage V";"Purine catabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Salinosporamide A biosynthesis";"Purine metabolism";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation" EDAN008630-PA 22 Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-195253 "S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex" EDAN014018-PA 3 Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60 "Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation" EDAN002027-PA 57 Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837 "APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation" EDAN005582-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN001170-PA 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" EDAN009286-PA 12 MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.222+2.1.1.64 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis" EDAN019410-PA 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" EDAN002747-PA 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" EDAN005114-PA 7 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039 "Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" EDAN002666-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" EDAN006591-PA 13 MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes" EDAN003303-PA 10 MetaCyc: PWY-6549;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42 "L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)" EDAN018971-PA 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" EDAN015941-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN000592-PA 17 Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6790901 "Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol" EDAN014233-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN008737-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN014055-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" EDAN013414-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN011397-PA 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" EDAN017113-PA 5 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" EDAN017737-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN014143-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" EDAN015457-PA 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" EDAN003170-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN010052-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN008284-PA 6 Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex" EDAN003962-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN018738-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN004947-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" EDAN007615-PA 5 Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-901042 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle" EDAN017344-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN001951-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN012869-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN006243-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN000586-PA 11 MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6963;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-5675;Reactome: R-HSA-8964539 "Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism" EDAN006075-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN000066-PA 56 Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8941858 "Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Hedgehog 'on' state";"Degradation of AXIN";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity" EDAN004288-PA 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN013141-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN018459-PA 24 Reactome: R-HSA-392851;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-416482 "Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"Ca2+ pathway";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events" EDAN007510-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" EDAN000341-PA 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" EDAN015534-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" EDAN002984-PA 11 MetaCyc: PWY-6964;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2 "Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis" EDAN012390-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" EDAN013882-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN004100-PA 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" EDAN017679-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN011769-PA 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" EDAN012685-PA 16 Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176409 "Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins" EDAN014570-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" EDAN001383-PA 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)" EDAN016023-PA 3 MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695 "Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation" EDAN012893-PA 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" EDAN017356-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN001335-PA 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" EDAN000419-PA 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" EDAN009595-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" EDAN017206-PA 7 KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-3385;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-7886 "Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PC";"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" EDAN003556-PA 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" EDAN005882-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" EDAN006905-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" EDAN006774-PA 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" EDAN005666-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN018234-PA 16 Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-5419276;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-5389840;Reactome: R-HSA-1799339 "Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial translation termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Mitochondrial translation elongation";"SRP-dependent cotranslational protein targeting to membrane" EDAN011432-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" EDAN010994-PA 7 MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948 "Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" EDAN012175-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN009270-PA 12 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" EDAN007871-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" EDAN003557-PA 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" EDAN010957-PA 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" EDAN017039-PA 7 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" EDAN013042-PA 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" EDAN000832-PA 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" EDAN018600-PA 4 Reactome: R-HSA-427652;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Sodium-coupled phosphate cotransporters";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" EDAN000364-PA 4 Reactome: R-HSA-5368286;Reactome: R-HSA-1799339;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN017095-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN016339-PA 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" EDAN015796-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" EDAN002915-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN001513-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN004949-PA 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" EDAN003463-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" EDAN011822-PA 4 Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211 "Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression";"ESR-mediated signaling" EDAN015969-PA 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" EDAN008848-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN017543-PA 15 Reactome: R-HSA-1433557;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-8853659 "Signaling by SCF-KIT";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"G alpha (q) signalling events";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"RET signaling" EDAN000255-PA 1 KEGG: 00750+2.6.99.2 "Vitamin B6 metabolism" EDAN019176-PA 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" EDAN000249-PA 6 MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism" EDAN000289-PA 7 Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400 "HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER" EDAN004316-PA 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" EDAN000214-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN015195-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN012300-PA 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" EDAN011051-PA 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" EDAN010316-PA 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy" EDAN018084-PA 5 Reactome: R-HSA-110330;Reactome: R-HSA-9608290;Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate processing";"Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" EDAN002781-PA 1 Reactome: R-HSA-373752 "Netrin-1 signaling" EDAN013487-PA 4 KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)" EDAN009426-PA 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" EDAN014148-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN008088-PA 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" EDAN009624-PA 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" EDAN008697-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN002355-PA 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" EDAN005833-PA 9 MetaCyc: PWY-6908;MetaCyc: PWY-6894;MetaCyc: PWY-6897;MetaCyc: PWY-6893;Reactome: R-HSA-2393930;MetaCyc: PWY-7357;MetaCyc: PWY-6907;KEGG: 00730+2.5.1.3;MetaCyc: PWY-7356 "Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis I (E. coli)";"Thiamine salvage II";"Thiamine diphosphate biosynthesis II (Bacillus)";"Phosphate bond hydrolysis by NUDT proteins";"Thiamine formation from pyrithiamine and oxythiamine (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism";"Thiamine salvage IV (yeast)" EDAN008287-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" EDAN004423-PA 6 Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN002137-PA 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" EDAN000490-PA 6 Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122 "Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" EDAN008084-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" EDAN005719-PA 3 KEGG: 00260+1.1.1.3;KEGG: 00300+1.1.1.3;KEGG: 00270+1.1.1.3 "Glycine, serine and threonine metabolism";"Lysine biosynthesis";"Cysteine and methionine metabolism" EDAN013000-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" EDAN008279-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN015018-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN016032-PA 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" EDAN002736-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN012917-PA 7 Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166 "Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA" EDAN009529-PA 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" EDAN019276-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" EDAN001715-PA 7 Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724 "Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription" EDAN012966-PA 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" EDAN006602-PA 3 KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17 "Purine metabolism";"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism" EDAN018968-PA 40 KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-6435;KEGG: 00627+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-6583;MetaCyc: PWY-7654;MetaCyc: PWY-6945;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6863;MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-7216;KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7656;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7606;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6946;MetaCyc: PWY-7094;MetaCyc: PWY-7401;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00062+4.2.1.17+1.1.1.35 "Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Aminobenzoate degradation";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Limonene and pinene degradation";"2-methylpropene degradation";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Benzoyl-coa degradation I (aerobic)";"Spodoptera littoralis pheromone biosynthesis";"Tryptophan metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Toluene degradation";"Androstenedione degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Butanoate metabolism";"beta-Alanine metabolism";"Caprolactam degradation";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid salvage";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Fatty acid elongation" EDAN011417-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" EDAN002874-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN002265-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN000133-PA 13 MetaCyc: PWY-5;MetaCyc: PWY-7400;Reactome: R-HSA-1268020;MetaCyc: PWY-4981;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5;KEGG: 00220+4.3.2.1;KEGG: 00220+2.1.3.3;MetaCyc: PWY-4984;MetaCyc: PWY-4983;KEGG: 00250+6.3.4.5;MetaCyc: PWY-5154 "Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Mitochondrial protein import";"L-proline biosynthesis II (from arginine)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Arginine biosynthesis";"Arginine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)" EDAN012076-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN018326-PA 6 Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II" EDAN000263-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN009082-PA 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" EDAN013741-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" EDAN015584-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN007290-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN005592-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN018314-PA 2 KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5 "Pentose and glucuronate interconversions";"Fructose and mannose metabolism" EDAN013220-PA 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation" EDAN006371-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" EDAN017117-PA 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" EDAN014432-PA 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" EDAN018888-PA 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" EDAN002674-PA 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation" EDAN004049-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" EDAN014721-PA 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" EDAN007179-PA 7 MetaCyc: PWY-6470;MetaCyc: PWY-6471;MetaCyc: PWY-5265;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" EDAN001198-PA 6 Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642 "Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" EDAN004292-PA 5 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" EDAN018699-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN009449-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN004340-PA 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" EDAN019461-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" EDAN018906-PA 3 KEGG: 00270+4.3.1.17;KEGG: 00260+4.3.1.17;Reactome: R-HSA-977347 "Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" EDAN008153-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" EDAN006429-PA 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN010769-PA 5 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20 "Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes" EDAN012018-PA 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" EDAN019216-PA 14 MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7124;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-6886;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7218 "Rubisco shunt";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" EDAN007248-PA 3 Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation" EDAN018620-PA 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" EDAN015330-PA 18 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-379726;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;KEGG: 00970+6.1.1.1 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Mitochondrial tRNA aminoacylation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aminoacyl-tRNA biosynthesis" EDAN001770-PA 1 Reactome: R-HSA-977347 "Serine biosynthesis" EDAN014040-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN010587-PA 3 Reactome: R-HSA-8957275;Reactome: R-HSA-5362798;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" EDAN008716-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN004221-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN000156-PA 16 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" EDAN003683-PA 13 Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5 "Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes" EDAN017836-PA 19 Reactome: R-HSA-5389840;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-5419276;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-5368286;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Mitochondrial translation elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial translation termination";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Mitochondrial translation initiation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" EDAN012872-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" EDAN000021-PA 10 MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.3.1 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"Purine metabolism" EDAN012064-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" EDAN013574-PA 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" EDAN005225-PA 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" EDAN013900-PA 33 Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Separation of Sister Chromatids" EDAN002853-PA 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" EDAN000223-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" EDAN007329-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN014994-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN004262-PA 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" EDAN016907-PA 10 Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148 "Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" EDAN007391-PA 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" EDAN014059-PA 8 Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-373080;Reactome: R-HSA-4086398;Reactome: R-HSA-4608870;Reactome: R-HSA-4641263;Reactome: R-HSA-5340588;Reactome: R-HSA-8856828 "WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"Ca2+ pathway";"Asymmetric localization of PCP proteins";"Regulation of FZD by ubiquitination";"RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis" EDAN002266-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" EDAN005017-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN016274-PA 5 Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580 "Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence" EDAN015807-PA 57 Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091 "Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Degradation of AXIN";"Hedgehog 'on' state";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells" EDAN005986-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN005313-PA 56 Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-75815 "Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Regulation of RAS by GAPs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D" EDAN001946-PA 1 Reactome: R-HSA-3295583 "TRP channels" EDAN007973-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" EDAN000609-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN016106-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" EDAN011667-PA 5 KEGG: 00900+1.17.7.4;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5;MetaCyc: PWY-7560;MetaCyc: PWY-7884 "Terpenoid backbone biosynthesis";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Methylerythritol phosphate pathway II";"Lipoprotein posttranslational modification" EDAN000307-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN005039-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN014231-PA 32 Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" EDAN005674-PA 1 KEGG: 00300+3.5.1.18 "Lysine biosynthesis" EDAN011221-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" EDAN016198-PA 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" EDAN018243-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" EDAN009320-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN016885-PA 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" EDAN006610-PA 56 Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084 "Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C" EDAN009863-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN004309-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN002993-PA 13 MetaCyc: PWY-5133;MetaCyc: PWY-5132;MetaCyc: PWY-7857;MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1 "Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Methane metabolism";"Ethanol oxidation";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism" EDAN002880-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN017154-PA 1 Reactome: R-HSA-419771 "Opsins" EDAN013204-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN011924-PA 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" EDAN018187-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN003123-PA 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" EDAN015391-PA 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" EDAN012790-PA 8 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6783310 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Fanconi Anemia Pathway" EDAN007811-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN003481-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN007861-PA 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" EDAN001738-PA 1 Reactome: R-HSA-71262 "Carnitine synthesis" EDAN016875-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" EDAN016950-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN011398-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" EDAN003505-PA 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300 "G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" EDAN003968-PA 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" EDAN016000-PA 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" EDAN009148-PA 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" EDAN003417-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN003119-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN007965-PA 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" EDAN000148-PA 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation" EDAN014648-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN011969-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" EDAN019325-PA 13 MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5913 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)" EDAN017747-PA 4 KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241 "beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"Peroxisomal protein import" EDAN005642-PA 21 MetaCyc: PWY-7440;MetaCyc: PWY-7814;MetaCyc: PWY-7316;MetaCyc: PWY-7104;MetaCyc: PWY-7301;MetaCyc: PWY-7657;MetaCyc: PWY-6973;MetaCyc: PWY-7315;MetaCyc: PWY-7688;KEGG: 00525+2.7.7.24;MetaCyc: PWY-6974;MetaCyc: PWY-6942;MetaCyc: PWY-6953;KEGG: 00523+2.7.7.24;MetaCyc: PWY-6808;MetaCyc: PWY-6976;MetaCyc: PWY-7312;MetaCyc: PWY-7413;KEGG: 00521+2.7.7.24;MetaCyc: PWY-7318;MetaCyc: PWY-7414 "Dtdp-beta-l-4-epi-vancosamine biosynthesis";"Dtdp-l-daunosamine biosynthesis";"Dtdp-n-acetylviosamine biosynthesis";"Dtdp-l-megosamine biosynthesis";"Dtdp-4-o-demethyl-beta-l-noviose biosynthesis";"Dtdp-beta-l-digitoxose biosynthesis";"Dtdp-d-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis";"Dtdp-n-acetylthomosamine biosynthesis";"Dtdp-d-ravidosamine and dTDP-4-acetyl-D-ravidosamine biosynthesis";"Acarbose and validamycin biosynthesis";"Dtdp-l-olivose biosynthesis";"Dtdp-d-desosamine biosynthesis";"Dtdp-3-acetamido-alpha-d-fucose biosynthesis";"Polyketide sugar unit biosynthesis";"Dtdp-d-forosamine biosynthesis";"Dtdp-l-mycarose biosynthesis";"Dtdp-d-beta-fucofuranose biosynthesis";"Dtdp-6-deoxy-alpha-d-allose biosynthesis";"Streptomycin biosynthesis";"Dtdp-3-acetamido-3,6-dideoxy-alpha-d-glucose biosynthesis";"Dtdp-alpha-d-mycaminose biosynthesis" EDAN005081-PA 12 MetaCyc: PWY-7118;MetaCyc: PWY-7857;MetaCyc: PWY-5132;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1 "Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Propanoate metabolism" EDAN008200-PA 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" EDAN010691-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN018840-PA 4 Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN003102-PA 5 MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" EDAN007499-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN016458-PA 14 MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" EDAN003308-PA 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" EDAN012336-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN000491-PA 6 KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6123 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I" EDAN019242-PA 5 KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937 "Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport" EDAN016135-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" EDAN004342-PA 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" EDAN011357-PA 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" EDAN005948-PA 6 KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane" EDAN003296-PA 7 MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.9 "5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"One carbon pool by folate" EDAN002445-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN002202-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN000594-PA 16 Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" EDAN003004-PA 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" EDAN016742-PA 5 Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" EDAN016471-PA 5 Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" EDAN004819-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN014108-PA 26 Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276 "MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Aggrephagy";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint" EDAN017627-PA 4 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation" EDAN004545-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" EDAN010278-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" EDAN002305-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN018101-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN006209-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" EDAN014159-PA 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" EDAN006875-PA 1 Reactome: R-HSA-70171 "Glycolysis" EDAN013439-PA 15 Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" EDAN007264-PA 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" EDAN000094-PA 4 KEGG: 00561+2.3.1.274;MetaCyc: PWY-4381;MetaCyc: PWY-5981;KEGG: 00061+2.3.1.180 "Glycerolipid metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"CDP-diacylglycerol biosynthesis III";"Fatty acid biosynthesis" EDAN011142-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" EDAN000200-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN008685-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" EDAN002503-PA 3 Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" EDAN019013-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" EDAN000030-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" EDAN012102-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN000496-PA 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN005512-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN012320-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" EDAN009684-PA 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" EDAN004410-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" EDAN014888-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN014505-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN005743-PA 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" EDAN013848-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" EDAN012023-PA 7 MetaCyc: PWY-5514;Reactome: R-HSA-71336;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I" EDAN001812-PA 17 Reactome: R-HSA-202424;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-4086398;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-975163;Reactome: R-HSA-1169091;Reactome: R-HSA-168638 "Downstream TCR signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"NOD1/2 Signaling Pathway" EDAN000613-PA 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" EDAN004256-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN009559-PA 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" EDAN009407-PA 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" EDAN017768-PA 3 KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661 "Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis" EDAN007052-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN007084-PA 5 Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211976 "PPARA activates gene expression";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Endogenous sterols" EDAN010521-PA 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" EDAN009045-PA 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" EDAN009114-PA 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" EDAN012128-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN019359-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" EDAN014119-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" EDAN007069-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" EDAN010789-PA 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" EDAN002004-PA 7 Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" EDAN002787-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN005800-PA 3 Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I" EDAN016446-PA 13 Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-983695 "Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" EDAN018362-PA 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" EDAN019481-PA 1 MetaCyc: PWY-7379 "Mrna capping II" EDAN003908-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN000137-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN008765-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN012234-PA 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" EDAN012224-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" EDAN005716-PA 3 MetaCyc: PWY-7159;KEGG: 00860+6.6.1.1;MetaCyc: PWY-5531 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)" EDAN012764-PA 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" EDAN014475-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN005761-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN006002-PA 7 MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943 "UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" EDAN003183-PA 4 Reactome: R-HSA-3359478;Reactome: R-HSA-71032;Reactome: R-HSA-3359475;Reactome: R-HSA-196741 "Defective MUT causes methylmalonic aciduria mut type";"Propionyl-CoA catabolism";"Defective MMAA causes methylmalonic aciduria type cblA";"Cobalamin (Cbl, vitamin B12) transport and metabolism" EDAN004302-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" EDAN015039-PA 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" EDAN005458-PA 16 MetaCyc: PWY-7124;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-2221;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-7218 "Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" EDAN003445-PA 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" EDAN004308-PA 4 MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" EDAN006889-PA 56 Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813 "UCH proteinases";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids" EDAN019343-PA 4 KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" EDAN019543-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" EDAN006360-PA 15 Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-2467813 "APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Separation of Sister Chromatids" EDAN006638-PA 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" EDAN002233-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN008706-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" EDAN000350-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" EDAN000636-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN001867-PA 11 Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" EDAN011214-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" EDAN012902-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN019438-PA 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" EDAN009377-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN016480-PA 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" EDAN003536-PA 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" EDAN006702-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN000752-PA 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" EDAN007343-PA 18 KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00360+2.6.1.1 "Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Arginine and proline metabolism";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism" EDAN003825-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" EDAN013499-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN005650-PA 4 KEGG: 00920+2.5.1.47;MetaCyc: PWY-6936;Reactome: R-HSA-1614603;KEGG: 00270+2.5.1.47 "Sulfur metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism" EDAN003325-PA 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" EDAN001249-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN019092-PA 7 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201 "Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis" EDAN017905-PA 5 MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527 "D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" EDAN018904-PA 13 MetaCyc: PWY-7218;MetaCyc: PWY-2221;KEGG: 00260+5.4.2.12;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-7124;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00680+5.4.2.12;KEGG: 00010+5.4.2.12;MetaCyc: PWY-1042;MetaCyc: PWY-5723 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycine, serine and threonine metabolism";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Rubisco shunt" EDAN008150-PA 24 Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-2132295 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"HCMV Early Events";"Aggrephagy";"Cilium Assembly";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation" EDAN003560-PA 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" EDAN013911-PA 2 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" EDAN007806-PA 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" EDAN013292-PA 14 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen degradation";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)" EDAN000018-PA 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" EDAN007145-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN018111-PA 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" EDAN016613-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN001531-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" EDAN018655-PA 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" EDAN012689-PA 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" EDAN008115-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN013457-PA 1 Reactome: R-HSA-8876725 "Protein methylation" EDAN014425-PA 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" EDAN014382-PA 4 Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590 "Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling" EDAN001178-PA 2 Reactome: R-HSA-390650;Reactome: R-HSA-416476 "Histamine receptors";"G alpha (q) signalling events" EDAN001162-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN000572-PA 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" EDAN017509-PA 13 KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220 "Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II" EDAN016413-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" EDAN014510-PA 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" EDAN005953-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" EDAN001625-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN015780-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN014319-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN003260-PA 11 MetaCyc: PWY-5485;MetaCyc: PWY-5482;KEGG: 00680+2.3.1.8;KEGG: 00620+2.3.1.8;KEGG: 00430+2.3.1.8;KEGG: 00640+2.3.1.8;MetaCyc: PWY-1281;MetaCyc: PWY-5497;KEGG: 00720+2.3.1.8;MetaCyc: PWY-6637;MetaCyc: PWY-8086 "Pyruvate fermentation to acetate IV";"Pyruvate fermentation to acetate II";"Methane metabolism";"Pyruvate metabolism";"Taurine and hypotaurine metabolism";"Propanoate metabolism";"Sulfoacetaldehyde degradation I";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Sulfolactate degradation II";"(S)-lactate fermentation to propanoate, acetate and hydrogen" EDAN000707-PA 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" EDAN002142-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" EDAN001985-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN002990-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" EDAN004866-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN006900-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN005617-PA 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" EDAN006129-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN016169-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" EDAN012327-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006661-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN006420-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN007429-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN008828-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN016247-PA 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" EDAN000106-PA 2 Reactome: R-HSA-499943;Reactome: R-HSA-936837 "Interconversion of nucleotide di- and triphosphates";"Ion transport by P-type ATPases" EDAN003834-PA 18 Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-8953750;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Transcriptional Regulation by E2F6";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" EDAN002303-PA 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" EDAN000256-PA 3 KEGG: 00300+1.1.1.3;KEGG: 00270+1.1.1.3;KEGG: 00260+1.1.1.3 "Lysine biosynthesis";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism" EDAN005830-PA 17 KEGG: 00051+2.7.1.90;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.90;MetaCyc: PWY-5484;KEGG: 00230+2.7.4.3;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00730+2.7.4.3;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7219;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-499943;KEGG: 00030+2.7.1.90;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11 "Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Thiamine metabolism";"Fructose and mannose metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pentose phosphate pathway";"Methane metabolism";"Interconversion of nucleotide di- and triphosphates";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism" EDAN006740-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" EDAN000692-PA 2 Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" EDAN000433-PA 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" EDAN000597-PA 19 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-5419276;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-5389840;Reactome: R-HSA-1799339 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial translation termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Mitochondrial translation elongation";"SRP-dependent cotranslational protein targeting to membrane" EDAN011286-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN006458-PA 5 Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994 "Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress" EDAN011240-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" EDAN011991-PA 56 Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154 "Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin" EDAN010083-PA 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" EDAN000954-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN008704-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" EDAN006095-PA 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" EDAN002807-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" EDAN000254-PA 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2" EDAN001897-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" EDAN011659-PA 4 MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+5.4.99.18 "Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" EDAN006623-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" EDAN006495-PA 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network" EDAN003259-PA 5 KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)" EDAN003150-PA 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" EDAN006359-PA 5 Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35 "Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" EDAN013973-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN011030-PA 13 MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" EDAN009816-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" EDAN018258-PA 11 MetaCyc: PWY-7344;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7328;Reactome: R-HSA-4615885;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-6527 "UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"SUMOylation of DNA replication proteins";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Stachyose degradation" EDAN004018-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" EDAN008144-PA 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" EDAN007930-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" EDAN000279-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" EDAN000531-PA 3 KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980 "Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis" EDAN010903-PA 56 Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603 "Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"UCH proteinases" EDAN019495-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN019269-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" EDAN015214-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN003664-PA 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination" EDAN014152-PA 11 Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation" EDAN015890-PA 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" EDAN009329-PA 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" EDAN003075-PA 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" EDAN018012-PA 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" EDAN010563-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN016560-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" EDAN007310-PA 7 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052 "Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis" EDAN012603-PA 9 Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation" EDAN010742-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN018334-PA 10 MetaCyc: PWY-5484;MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70171 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Glycolysis" EDAN000957-PA 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" EDAN000508-PA 5 Reactome: R-HSA-110330;Reactome: R-HSA-9608290;Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate processing";"Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" EDAN001577-PA 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" EDAN000383-PA 4 MetaCyc: PWY-5659;KEGG: 00520+2.7.7.13;KEGG: 00051+2.7.7.13;MetaCyc: PWY-882 "GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)" EDAN018747-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN008331-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" EDAN016201-PA 22 MetaCyc: PWY-6958;MetaCyc: PWY-7053;MetaCyc: PWY-5080;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-7726;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-7619;MetaCyc: PWY-7606;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7728 "Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)" EDAN014596-PA 1 Reactome: R-HSA-2028269 "Signaling by Hippo" EDAN010058-PA 5 Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome" EDAN010307-PA 17 Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-3270619;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-1834949 "Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"IRF3-mediated induction of type I IFN";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cytosolic sensors of pathogen-associated DNA" EDAN006409-PA 8 Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-113501 "Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"DNA replication initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" EDAN012632-PA 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" EDAN008102-PA 8 Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" EDAN016240-PA 7 MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-6596 "Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Adenosine nucleotides degradation I" EDAN008997-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN005275-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" EDAN010113-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN000023-PA 5 MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37 "Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism" EDAN007218-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" EDAN013178-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" EDAN011435-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" EDAN003175-PA 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" EDAN008242-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN010140-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN006641-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN001379-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-2206291;Reactome: R-HSA-2024096 "Neutrophil degranulation";"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation" EDAN012438-PA 16 Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-69017 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6" EDAN005702-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN000969-PA 5 Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1" EDAN013080-PA 4 KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132 "Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" EDAN001234-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" EDAN000551-PA 9 KEGG: 00790+3.5.4.25;KEGG: 00740+3.5.4.25;MetaCyc: PWY-6167;MetaCyc: PWY-7991;KEGG: 00740+2.5.1.78;KEGG: 00740+4.1.99.12;MetaCyc: PWY-7539;KEGG: 00740+3.5.4.25+4.1.99.12;MetaCyc: PWY-6168 "Folate biosynthesis";"Riboflavin metabolism";"Flavin biosynthesis II (archaea)";"Toxoflavin biosynthesis";"Riboflavin metabolism";"Riboflavin metabolism";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)" EDAN018561-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" EDAN012020-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" EDAN001290-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" EDAN006103-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" EDAN014846-PA 5 MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781 "Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)" EDAN002537-PA 9 KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7003 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol" EDAN007917-PA 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" EDAN009282-PA 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" EDAN003389-PA 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN002845-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" EDAN016955-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" EDAN005202-PA 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" EDAN018884-PA 3 MetaCyc: PWY-2941;KEGG: 00300+5.1.1.7;MetaCyc: PWY-5097 "L-lysine biosynthesis II";"Lysine biosynthesis";"L-lysine biosynthesis VI" EDAN001154-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" EDAN006241-PA 5 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination" EDAN011242-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" EDAN005780-PA 2 KEGG: 00061+2.3.1.180;MetaCyc: PWY-4381 "Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)" EDAN003394-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN004836-PA 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" EDAN019469-PA 5 Reactome: R-HSA-4615885;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "SUMOylation of DNA replication proteins";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" EDAN015948-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN006887-PA 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" EDAN004199-PA 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" EDAN007593-PA 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206302 "CS/DS degradation";"HS-GAG degradation";"MPS I - Hurler syndrome" EDAN013975-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" EDAN013821-PA 8 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex" EDAN000296-PA 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" EDAN001069-PA 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" EDAN018879-PA 2 MetaCyc: PWY-5344;KEGG: 00270+2.3.1.31 "L-homocysteine biosynthesis";"Cysteine and methionine metabolism" EDAN003012-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" EDAN019010-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN009352-PA 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" EDAN018206-PA 4 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis" EDAN014367-PA 6 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" EDAN013190-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN008910-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" EDAN014514-PA 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" EDAN002640-PA 1 Reactome: R-HSA-1221632 "Meiotic synapsis" EDAN000804-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN014504-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN017833-PA 16 Reactome: R-HSA-1799339;Reactome: R-HSA-5389840;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-5419276;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-5368286;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Mitochondrial translation elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Mitochondrial translation termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Mitochondrial translation initiation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" EDAN018638-PA 18 MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Arginine and proline metabolism";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Coenzyme M biosynthesis II";"Phenylalanine metabolism" EDAN004526-PA 7 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-171319 "HATs acetylate histones";"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"UCH proteinases";"Telomere Extension By Telomerase" EDAN001667-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN003230-PA 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" EDAN016683-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN011950-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN013171-PA 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" EDAN000564-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN005842-PA 6 MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)" EDAN004328-PA 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" EDAN018443-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" EDAN014010-PA 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" EDAN006426-PA 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" EDAN017096-PA 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" EDAN000087-PA 7 KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00770+2.1.2.11;Reactome: R-HSA-196757;MetaCyc: PWY-6654;KEGG: 00670+1.5.1.20 "Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Folate transformations I";"Pantothenate and CoA biosynthesis";"Metabolism of folate and pterines";"Phosphopantothenate biosynthesis III (archaebacteria)";"One carbon pool by folate" EDAN019038-PA 6 KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;Reactome: R-HSA-71336 "Pentose and glucuronate interconversions";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" EDAN010963-PA 57 Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184 "Degradation of AXIN";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"UCH proteinases";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" EDAN001758-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" EDAN002544-PA 6 Reactome: R-HSA-173599;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820 "Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)" EDAN014336-PA 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation" EDAN012112-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" EDAN011985-PA 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" EDAN011194-PA 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"Circadian Clock";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation" EDAN016047-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" EDAN013648-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN017942-PA 14 Reactome: R-HSA-2565942;Reactome: R-HSA-428890;Reactome: R-HSA-380259;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-380284;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Role of ABL in ROBO-SLIT signaling";"Loss of Nlp from mitotic centrosomes";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Loss of proteins required for interphase microtubule organization from the centrosome";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" EDAN003435-PA 2 MetaCyc: PWY-7380;KEGG: 00780+2.8.1.6 "Biotin biosynthesis from 8-amino-7-oxononanoate II";"Biotin metabolism" EDAN005662-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN007465-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN003084-PA 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" EDAN009102-PA 24 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-389357;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;Reactome: R-HSA-114604;Reactome: R-HSA-444257;Reactome: R-HSA-165158;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Integrin signaling";"CD28 dependent PI3K/Akt signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"GPVI-mediated activation cascade";"RSK activation";"Activation of AKT2";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"mTOR signaling pathway" EDAN002063-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN015808-PA 3 Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12 "Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism" EDAN015216-PA 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" EDAN010056-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN012446-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN011331-PA 8 MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" EDAN004126-PA 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" EDAN009230-PA 1 Reactome: R-HSA-71262 "Carnitine synthesis" EDAN015842-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN000803-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN000624-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN003387-PA 7 MetaCyc: PWY-5097;MetaCyc: PWY-2941;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2942;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7;Reactome: R-HSA-389661 "L-lysine biosynthesis VI";"L-lysine biosynthesis II";"Lysine biosynthesis";"L-lysine biosynthesis III";"Dipicolinate biosynthesis";"Monobactam biosynthesis";"Glyoxylate metabolism and glycine degradation" EDAN007316-PA 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" EDAN006375-PA 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" EDAN007188-PA 1 Reactome: R-HSA-9636383 "Prevention of phagosomal-lysosomal fusion" EDAN018744-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" EDAN015305-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN015970-PA 8 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6" EDAN019064-PA 5 KEGG: 00300+1.17.1.8;KEGG: 00261+1.17.1.8;MetaCyc: PWY-2942;MetaCyc: PWY-2941;MetaCyc: PWY-5097 "Lysine biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis III";"L-lysine biosynthesis II";"L-lysine biosynthesis VI" EDAN012716-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" EDAN017992-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN002830-PA 27 Reactome: R-HSA-5467340;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-5610783;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-8939902;Reactome: R-HSA-5358752;Reactome: R-HSA-399956;Reactome: R-HSA-5250924;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4641262;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-3371453;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5610785;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-75815;Reactome: R-HSA-5467348 "AXIN missense mutants destabilize the destruction complex";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of GLI2 by the proteasome";"Thermogenesis";"APC truncation mutants have impaired AXIN binding";"Regulation of RUNX2 expression and activity";"T41 mutants of beta-catenin aren't phosphorylated";"CRMPs in Sema3A signaling";"B-WICH complex positively regulates rRNA expression";"Relaxin signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human papillomavirus infection";"S45 mutants of beta-catenin aren't phosphorylated";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of HSF1-mediated heat shock response";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"GLI3 is processed to GLI3R by the proteasome";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ubiquitin-dependent degradation of Cyclin D";"Truncations of AMER1 destabilize the destruction complex" EDAN005766-PA 8 MetaCyc: PWY-8072;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;MetaCyc: PWY-7383;Reactome: R-HSA-5693579;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;Reactome: R-HSA-5685942 "Alanine racemization";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Anaerobic energy metabolism (invertebrates, cytosol)";"Homologous DNA Pairing and Strand Exchange";"D-Alanine metabolism";"Ansatrienin biosynthesis";"HDR through Homologous Recombination (HRR)" EDAN001333-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN002487-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN002081-PA 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" EDAN000349-PA 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" EDAN013468-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN010277-PA 10 Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Galactose metabolism";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation" EDAN018997-PA 3 Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" EDAN014535-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" EDAN005826-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN007219-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits" EDAN015623-PA 56 Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"Hedgehog 'on' state";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Regulation of RAS by GAPs" EDAN000589-PA 2 MetaCyc: PWY-6164;KEGG: 00400+4.2.3.4 "3-dehydroquinate biosynthesis I";"Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN000498-PA 2 KEGG: 00260+4.2.1.20;KEGG: 00400+4.2.1.20 "Glycine, serine and threonine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" EDAN002823-PA 10 MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-69205;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7187;Reactome: R-HSA-499943;KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"One carbon pool by folate";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" EDAN008402-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN019230-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN012602-PA 5 Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism" EDAN018058-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" EDAN007072-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN014815-PA 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" EDAN007616-PA 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins" EDAN016276-PA 9 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972 "Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" EDAN007847-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" EDAN003362-PA 6 MetaCyc: PWY-5265;KEGG: 00550+2.4.1.129;MetaCyc: PWY-6385;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.129+3.4.16.4 "Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis" EDAN013564-PA 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" EDAN016738-PA 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN008905-PA 5 Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-5362768;MetaCyc: PWY-7511 "ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination" EDAN000283-PA 4 KEGG: 00230+5.4.99.18;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III" EDAN002653-PA 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-114608 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation" EDAN016670-PA 5 MetaCyc: PWY-7210;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism" EDAN009284-PA 3 KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" EDAN004129-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" EDAN001317-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN014308-PA 1 Reactome: R-HSA-5676934 "Protein repair" EDAN009255-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" EDAN004827-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" EDAN015448-PA 7 Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth" EDAN009748-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN003193-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" EDAN012715-PA 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" EDAN005678-PA 11 MetaCyc: PWY-6113;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-5971;MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWY-6519;MetaCyc: PWY-6282;KEGG: 00061+1.3.1.9;MetaCyc: PWY-5973 "Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis" EDAN017351-PA 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" EDAN002301-PA 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" EDAN000116-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN003327-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN015354-PA 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" EDAN012857-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN019476-PA 13 KEGG: 00260+5.4.2.12;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-2221;KEGG: 00010+5.4.2.12;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.12 "Glycine, serine and threonine metabolism";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism" EDAN006901-PA 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" EDAN015093-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN004965-PA 27 Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453 "tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response" EDAN011748-PA 5 Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-3371571 "mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation" EDAN019279-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" EDAN019257-PA 6 MetaCyc: PWY-5941;MetaCyc: PWY-6731;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;MetaCyc: PWY-6737 "Glycogen degradation II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation V" EDAN002046-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN007963-PA 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" EDAN011662-PA 18 Reactome: R-HSA-71403;KEGG: 00640+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00020+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00380+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-71064;MetaCyc: PWY-5046;Reactome: R-HSA-389661;MetaCyc: PWY-5084;Reactome: R-HSA-204174;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4 "Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Pyruvate metabolism";"Glycine degradation";"Citrate cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Glycine, serine and threonine metabolism";"Pyruvate metabolism";"Tryptophan metabolism";"Signaling by Retinoic Acid";"Lysine catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine degradation";"Glycolysis / Gluconeogenesis" EDAN009749-PA 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" EDAN014689-PA 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" EDAN013515-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" EDAN002494-PA 6 MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" EDAN017431-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN006647-PA 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" EDAN000560-PA 5 KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+1.2.1.70 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" EDAN002974-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN001276-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN017330-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN009210-PA 7 MetaCyc: PWY-5097;MetaCyc: PWY-2941;MetaCyc: PWY-2942;KEGG: 00300+4.3.3.7;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7;Reactome: R-HSA-389661 "L-lysine biosynthesis VI";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"Lysine biosynthesis";"Dipicolinate biosynthesis";"Monobactam biosynthesis";"Glyoxylate metabolism and glycine degradation" EDAN003520-PA 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" EDAN007461-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" EDAN011610-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" EDAN000529-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN017184-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN004348-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" EDAN005412-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN007642-PA 7 Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" EDAN008889-PA 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693565 "Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" EDAN017430-PA 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" EDAN018964-PA 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" EDAN012362-PA 5 MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" EDAN012863-PA 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" EDAN013503-PA 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" EDAN019366-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN003419-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN000303-PA 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" EDAN011650-PA 4 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" EDAN002442-PA 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" EDAN003353-PA 11 KEGG: 00220+6.3.4.5;MetaCyc: PWY-5;Reactome: R-HSA-70635;Reactome: R-HSA-1268020;MetaCyc: PWY-7400;MetaCyc: PWY-4981;KEGG: 00220+2.1.3.3;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-4984 "Arginine biosynthesis";"Canavanine biosynthesis";"Urea cycle";"Mitochondrial protein import";"L-arginine biosynthesis IV (archaebacteria)";"L-proline biosynthesis II (from arginine)";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle" EDAN012658-PA 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" EDAN006077-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN008271-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" EDAN001669-PA 8 Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-68962 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex" EDAN001739-PA 19 Reactome: R-HSA-5625970;Reactome: R-HSA-428543;Reactome: R-HSA-3928662;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-5687128;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-182971;Reactome: R-HSA-5663220 "RHO GTPases activate KTN1";"Inactivation of CDC42 and RAC1";"EPHB-mediated forward signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"MAPK6/MAPK4 signaling";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"Myogenesis";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"EGFR downregulation";"RHO GTPases Activate Formins" EDAN013377-PA 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" EDAN008900-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN005263-PA 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" EDAN005807-PA 2 Reactome: R-HSA-8964539;KEGG: 00240+2.7.4.22 "Glutamate and glutamine metabolism";"Pyrimidine metabolism" EDAN002196-PA 25 Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-381771;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-400042 "G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G-protein activation";"Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion" EDAN001853-PA 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" EDAN018391-PA 7 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-1268020;Reactome: R-HSA-390471;Reactome: R-HSA-8869496 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Mitochondrial protein import";"Association of TriC/CCT with target proteins during biosynthesis";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" EDAN004768-PA 5 KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;MetaCyc: PWY-7782 "Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Plasmalogen biosynthesis" EDAN007893-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" EDAN006029-PA 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" EDAN002318-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN014737-PA 6 Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" EDAN001184-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN008435-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN005909-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" EDAN015826-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN018388-PA 5 MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892 "Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)" EDAN013876-PA 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes" EDAN006983-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" EDAN000024-PA 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" EDAN015420-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN008683-PA 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" EDAN009106-PA 3 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847 "UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones" EDAN003313-PA 4 Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37 "DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism" EDAN004963-PA 27 Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531 "SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus" EDAN009069-PA 22 MetaCyc: PWY-7385;MetaCyc: PWY-5054;MetaCyc: PWY-622;Reactome: R-HSA-70171;MetaCyc: PWY-6981;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.9;MetaCyc: PWY-621;MetaCyc: PWY-7238;KEGG: 00500+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-3801;MetaCyc: PWY-7347;MetaCyc: PWY-5384;MetaCyc: PWY-5659;MetaCyc: PWY-5514;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;KEGG: 00010+5.3.1.9;MetaCyc: PWY-6142;Reactome: R-HSA-70263 "1,3-propanediol biosynthesis (engineered)";"D-sorbitol biosynthesis I";"Starch biosynthesis";"Glycolysis";"Chitin biosynthesis";"Pentose phosphate pathway";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation III (sucrose invertase)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis" EDAN000408-PA 6 MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2 "UMP biosynthesis I";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism" EDAN012366-PA 12 Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167243 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery" EDAN017249-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN019493-PA 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" EDAN012788-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" EDAN012241-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN010958-PA 57 Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-4608870 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins" EDAN001253-PA 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" EDAN010577-PA 23 Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-202040 "G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation" EDAN018853-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN018085-PA 3 KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1 "Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway" EDAN019102-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN007372-PA 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" EDAN015945-PA 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" EDAN019290-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" EDAN013820-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" EDAN017984-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN001299-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN000206-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" EDAN016045-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN000478-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" EDAN003843-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN008503-PA 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856 "Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination" EDAN007609-PA 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" EDAN015239-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" EDAN014842-PA 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" EDAN011966-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" EDAN018750-PA 6 MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-6708;KEGG: 00130+4.1.1.98 "Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" EDAN010636-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" EDAN005037-PA 3 Reactome: R-HSA-382556;Reactome: R-HSA-1989781;Reactome: R-HSA-5678771 "ABC-family proteins mediated transport";"PPARA activates gene expression";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1" EDAN003178-PA 4 MetaCyc: PWY-6661;KEGG: 00405+4.1.3.27;KEGG: 00400+4.1.3.27;MetaCyc: PWY-5958 "4-hydroxy-2(1H)-quinolone biosynthesis";"Phenazine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Acridone alkaloid biosynthesis" EDAN009047-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN000038-PA 10 MetaCyc: PWY-6886;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-8004 "1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Entner-Doudoroff pathway I" EDAN014305-PA 9 Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430 "DNA replication initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation" EDAN014179-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN003320-PA 5 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" EDAN011819-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN000918-PA 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" EDAN011712-PA 6 Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"Pentose and glucuronate interconversions" EDAN007694-PA 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" EDAN007804-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" EDAN009876-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" EDAN014696-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" EDAN018664-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN017842-PA 1 Reactome: R-HSA-6783984 "Glycine degradation" EDAN009380-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" EDAN002026-PA 57 Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-68949;Reactome: R-HSA-174084 "Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C" EDAN018901-PA 33 Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159230 "snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA" EDAN007331-PA 7 Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852 "AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy" EDAN005950-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" EDAN012591-PA 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" EDAN010481-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN012577-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN017223-PA 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" EDAN000384-PA 7 KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Pentose phosphate pathway";"Gluconeogenesis" EDAN006305-PA 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" EDAN015626-PA 17 Reactome: R-HSA-113501;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-2559580;Reactome: R-HSA-69231;Reactome: R-HSA-139915;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-69202;Reactome: R-HSA-9616222;Reactome: R-HSA-111448;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-2559585 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Oxidative Stress Induced Senescence";"Cyclin D associated events in G1";"Activation of PUMA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"Cyclin E associated events during G1/S transition";"Transcriptional regulation of granulopoiesis";"Activation of NOXA and translocation to mitochondria";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Oncogene Induced Senescence" EDAN004326-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis" EDAN000195-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN000424-PA 6 MetaCyc: PWY-7980;MetaCyc: PWY-6168;KEGG: 00190+7.1.2.2;KEGG: 00740+2.5.1.9;KEGG: 00195+7.1.2.2;MetaCyc: PWY-6167 "ATP biosynthesis";"Flavin biosynthesis III (fungi)";"Oxidative phosphorylation";"Riboflavin metabolism";"Photosynthesis";"Flavin biosynthesis II (archaea)" EDAN003409-PA 3 KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" EDAN009840-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" EDAN005778-PA 14 MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWY-7663;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5367;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100;KEGG: 00780+1.1.1.100;MetaCyc: PWY-6282;MetaCyc: PWY-6519 "(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Biotin metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I" EDAN005657-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN017659-PA 6 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin" EDAN000054-PA 2 MetaCyc: PWY-6700;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" EDAN010101-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN002411-PA 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" EDAN011722-PA 3 KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" EDAN011596-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN012835-PA 42 MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7401;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-5136;MetaCyc: PWY-7656;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6944;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5109;MetaCyc: PWY-6863;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-5789;MetaCyc: PWY-6583;MetaCyc: PWY-7654;MetaCyc: PWY-6945;MetaCyc: PWY-6435;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17 "Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Fatty acid salvage";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid elongation";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to butanol II (engineered)";"Benzoate degradation";"beta-Alanine metabolism";"Caprolactam degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"Tryptophan metabolism";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Androstenedione degradation";"Toluene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Glutaryl-coa degradation";"Geraniol degradation";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to hexanol (engineered)";"Limonene and pinene degradation";"2-methylpropene degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid degradation";"Aminobenzoate degradation";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism" EDAN009912-PA 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" EDAN006237-PA 3 Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174 "Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN013595-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN009196-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" EDAN018245-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" EDAN019517-PA 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" EDAN002558-PA 8 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation" EDAN005628-PA 6 Reactome: R-HSA-8950505;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-8862803 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" EDAN019405-PA 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" EDAN003254-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" EDAN009394-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN002675-PA 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" EDAN012263-PA 1 Reactome: R-HSA-6783984 "Glycine degradation" EDAN007857-PA 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" EDAN017956-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" EDAN007441-PA 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" EDAN007564-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN013297-PA 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" EDAN011321-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN004511-PA 33 Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159236 "Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Mitotic Prometaphase";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN019104-PA 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" EDAN018116-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN000704-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" EDAN003281-PA 19 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-5419276;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-5368286;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-5389840;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial translation termination";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Mitochondrial translation initiation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Mitochondrial translation elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination" EDAN019505-PA 40 MetaCyc: PWY-6435;KEGG: 00627+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-6863;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-7726;MetaCyc: PWY-5109;MetaCyc: PWY-5789;MetaCyc: PWY-6583;MetaCyc: PWY-7654;MetaCyc: PWY-6945;MetaCyc: PWY-5136;MetaCyc: PWY-7656;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7401;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-6946 "4-hydroxybenzoate biosynthesis III (plants)";"Aminobenzoate degradation";"Fatty acid degradation";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to hexanol (engineered)";"Limonene and pinene degradation";"2-methylpropene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Spodoptera littoralis pheromone biosynthesis";"Tryptophan metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Toluene degradation";"Androstenedione degradation";"Butanoate metabolism";"Geraniol degradation";"Glutaryl-coa degradation";"alpha-Linolenic acid metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Fatty acid salvage";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Fatty acid elongation";"Benzoate degradation";"Caprolactam degradation";"beta-Alanine metabolism";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)" EDAN010454-PA 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" EDAN014412-PA 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" EDAN015384-PA 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" EDAN015786-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN004011-PA 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" EDAN018189-PA 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" EDAN013742-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" EDAN005921-PA 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" EDAN008557-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN015978-PA 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" EDAN007240-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" EDAN002311-PA 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" EDAN008218-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" EDAN009564-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN005771-PA 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" EDAN000110-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN002995-PA 7 Reactome: R-HSA-381426;Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-140837;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"Intrinsic Pathway of Fibrin Clot Formation";"Platelet degranulation";"G alpha (i) signalling events";"G alpha (q) signalling events" EDAN011555-PA 2 KEGG: 00051+5.3.1.5;KEGG: 00040+5.3.1.5 "Fructose and mannose metabolism";"Pentose and glucuronate interconversions" EDAN000277-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" EDAN019329-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" EDAN000040-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN004375-PA 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids" EDAN014911-PA 17 Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-69091 "Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Polymerase switching" EDAN016506-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" EDAN019128-PA 3 KEGG: 00270+1.1.1.3;KEGG: 00300+1.1.1.3;KEGG: 00260+1.1.1.3 "Cysteine and methionine metabolism";"Lysine biosynthesis";"Glycine, serine and threonine metabolism" EDAN000006-PA 3 Reactome: R-HSA-70895;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" EDAN002107-PA 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" EDAN003961-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN013032-PA 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" EDAN004437-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" EDAN017749-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" EDAN015501-PA 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" EDAN008875-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" EDAN007064-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN003041-PA 12 KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042 "Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)" EDAN019612-PA 5 Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-5334118 "NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"DNA methylation" EDAN012319-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" EDAN011998-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN019084-PA 2 Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Pyrimidine salvage";"Pyrimidine catabolism" EDAN016208-PA 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" EDAN000291-PA 6 MetaCyc: PWY-5316;MetaCyc: PWY-7342;KEGG: 00760+1.4.3.16;Reactome: R-HSA-611105;Reactome: R-HSA-71403;KEGG: 00250+1.4.3.16 "Nicotine biosynthesis";"Superpathway of nicotine biosynthesis";"Nicotinate and nicotinamide metabolism";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Alanine, aspartate and glutamate metabolism" EDAN009676-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN004789-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" EDAN018891-PA 3 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2 "ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis" EDAN005640-PA 6 Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52 "Serine biosynthesis";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Vitamin B6 metabolism" EDAN002359-PA 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" EDAN011804-PA 5 Reactome: R-HSA-199220;MetaCyc: PWY-6289;MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1 "Vitamin B5 (pantothenate) metabolism";"Petrobactin biosynthesis";"Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation" EDAN006018-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" EDAN009104-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN003144-PA 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" EDAN002870-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" EDAN011704-PA 10 MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5844;MetaCyc: PWY-5839;MetaCyc: PWY-5895;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5891 "Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis" EDAN018713-PA 10 KEGG: 00250+6.3.5.5;Reactome: R-HSA-8949664;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-6749;MetaCyc: PWY-7791;MetaCyc: PWY-5154;MetaCyc: PWY-7400;MetaCyc: PWY-7790;KEGG: 00240+6.3.5.5 "Alanine, aspartate and glutamate metabolism";"Processing of SMDT1";"Amino sugar and nucleotide sugar metabolism";"UMP biosynthesis I";"CMP-legionaminate biosynthesis I";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine metabolism" EDAN002365-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" EDAN000830-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" EDAN008807-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" EDAN000956-PA 7 Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" EDAN015803-PA 57 Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69601 "Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Ub-specific processing proteases";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RAS by GAPs";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" EDAN017829-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" EDAN019548-PA 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" EDAN008553-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" EDAN017594-PA 10 MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695 "Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Other glycan degradation";"Glycosaminoglycan degradation";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Neutrophil degranulation" EDAN018919-PA 14 MetaCyc: PWY-7663;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100;MetaCyc: PWY-5973;KEGG: 00780+1.1.1.100 "Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Biotin metabolism" EDAN015739-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN019417-PA 1 KEGG: 00900+1.17.7.3 "Terpenoid backbone biosynthesis" EDAN000332-PA 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" EDAN000132-PA 4 MetaCyc: PWY-5097;MetaCyc: PWY-2941;MetaCyc: PWY-2942;KEGG: 00300+4.1.1.20 "L-lysine biosynthesis VI";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"Lysine biosynthesis" EDAN003944-PA 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" EDAN004554-PA 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" EDAN004286-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN003160-PA 5 MetaCyc: PWY-6385;MetaCyc: PWY-6470;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.129 "Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis" EDAN018063-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN005736-PA 7 KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-389661 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" EDAN010401-PA 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" EDAN012003-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN004075-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" EDAN009117-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" EDAN008718-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN008138-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" EDAN000029-PA 15 MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-7383;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Purine metabolism";"Superpathway of glucose and xylose degradation" EDAN007675-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" EDAN011449-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" EDAN015932-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" EDAN011681-PA 3 MetaCyc: PWY-6167;KEGG: 00740+2.5.1.78;MetaCyc: PWY-6168 "Flavin biosynthesis II (archaea)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)" EDAN007980-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" EDAN006791-PA 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events" EDAN001963-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" EDAN010974-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" EDAN004077-PA 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" EDAN019375-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" EDAN001578-PA 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" EDAN000557-PA 6 KEGG: 00230+2.4.2.8;MetaCyc: PWY-6620;MetaCyc: PWY-6599;KEGG: 00983+2.4.2.8;MetaCyc: PWY-6609;MetaCyc: PWY-6610 "Purine metabolism";"Guanine and guanosine salvage";"Guanine and guanosine salvage II";"Drug metabolism - other enzymes";"Adenine and adenosine salvage III";"Adenine salvage" EDAN016243-PA 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" EDAN004359-PA 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" EDAN011131-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" EDAN006739-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" EDAN009538-PA 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" EDAN000507-PA 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" EDAN003603-PA 31 MetaCyc: PWY-5147;MetaCyc: PWY-7664;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-8049;MetaCyc: PWY-7663;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-6519;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-8047;Reactome: R-HSA-199220;MetaCyc: PWY-7388;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-7746;MetaCyc: PWY-5994;MetaCyc: PWY-6282;MetaCyc: PWY-4381 "Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Pederin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Bryostatin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Biotin metabolism";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (bacteria and plants)" EDAN000542-PA 8 KEGG: 00860+2.7.7.62+2.7.1.156;MetaCyc: PWY-7971;MetaCyc: PWY-7962;MetaCyc: PWY-6269;Reactome: R-HSA-196741;MetaCyc: PWY-7972;KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471 "Porphyrin and chlorophyll metabolism";"Adenosylcobinamide-gdp salvage from cobinamide I";"Adenosylcobinamide-gdp biosynthesis from cobyrinate a,c-diamide";"Superpathway of adenosylcobalamin salvage from cobinamide II";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Adenosylcobinamidegdp salvage from cobinamide II";"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB" EDAN004329-PA 7 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22 "Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism" EDAN016445-PA 13 Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-139853 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels" EDAN002792-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN010486-PA 33 Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-165054 "tRNA processing in the nucleus";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Mitotic Prometaphase";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA" EDAN017878-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis" EDAN011724-PA 6 Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II" EDAN006066-PA 14 Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" EDAN000253-PA 11 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-5368286;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-5419276;Reactome: R-HSA-380994;Reactome: R-HSA-5389840;Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Mitochondrial translation initiation";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Mitochondrial translation termination";"ATF4 activates genes in response to endoplasmic reticulum stress";"Mitochondrial translation elongation";"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" EDAN004991-PA 3 Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17 "Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis" EDAN011144-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN007253-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" EDAN008159-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" EDAN013170-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" EDAN008736-PA 6 Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing" EDAN010450-PA 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" EDAN008933-PA 11 Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" EDAN003342-PA 7 MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis" EDAN008849-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN007089-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" EDAN015019-PA 14 Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593 "TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity" EDAN010171-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" EDAN000117-PA 3 KEGG: 00300+5.1.1.7;MetaCyc: PWY-2941;MetaCyc: PWY-5097 "Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis VI" EDAN005899-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" EDAN015877-PA 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" EDAN013085-PA 5 Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757 "CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation" EDAN018103-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" EDAN000569-PA 2 KEGG: 00340+5.3.1.16;KEGG: 00340+4.3.2.10 "Histidine metabolism";"Histidine metabolism" EDAN007936-PA 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" EDAN004030-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" EDAN001693-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" EDAN001194-PA 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1" EDAN009830-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN011369-PA 1 Reactome: R-HSA-156588 "Glucuronidation" EDAN002087-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" EDAN015027-PA 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" EDAN006353-PA 2 Reactome: R-HSA-418346;Reactome: R-HSA-139853 "Platelet homeostasis";"Elevation of cytosolic Ca2+ levels" EDAN010595-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN010455-PA 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" EDAN013438-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN004173-PA 14 Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-6798695;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2894862 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Neutrophil degranulation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" EDAN011916-PA 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" EDAN014149-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" EDAN000423-PA 7 MetaCyc: PWY-241;MetaCyc: PWY-7115;KEGG: 00710+2.7.9.1;MetaCyc: PWY-7117;KEGG: 00620+2.7.9.1;MetaCyc: PWY-6549;KEGG: 00720+2.7.9.1 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Pyruvate metabolism";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes" EDAN001596-PA 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" EDAN000228-PA 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" EDAN012833-PA 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" EDAN000081-PA 6 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import" EDAN013969-PA 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" EDAN009100-PA 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" EDAN018198-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" EDAN013788-PA 7 MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis" EDAN000718-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" EDAN017104-PA 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" EDAN002947-PA 3 Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" EDAN016035-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN001377-PA 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" EDAN004655-PA 10 Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-8849932 "Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules" EDAN016060-PA 8 Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" EDAN017567-PA 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" EDAN008149-PA 24 Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833 "COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"HCMV Early Events";"Aggrephagy";"Cilium Assembly" EDAN005935-PA 9 KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533 "Glutathione metabolism";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis" EDAN002172-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" EDAN011167-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" EDAN011512-PA 5 Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" EDAN015547-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN012062-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" EDAN003148-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" EDAN016470-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" EDAN007258-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" EDAN013057-PA 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" EDAN015574-PA 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" EDAN016849-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" EDAN000184-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" EDAN012384-PA 1 Reactome: R-HSA-8951664 "Neddylation" EDAN002197-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" EDAN005089-PA 29 Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-912446;Reactome: R-HSA-5696397;Reactome: R-HSA-68962 "Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex" EDAN011043-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" EDAN011407-PA 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" EDAN015998-PA 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" EDAN011552-PA 17 Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-6644;MetaCyc: PWY-5695;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5532;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-7179;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1 "Purine catabolism";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Salinosporamide A biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Guanine and guanosine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II" EDAN003312-PA 2 KEGG: 00730+4.1.99.17;MetaCyc: PWY-6890 "Thiamine metabolism";"4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis" EDAN013949-PA 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" EDAN002292-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" EDAN009487-PA 1 Reactome: R-HSA-8951664 "Neddylation"