Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
EAFF007639-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
EAFF000384-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF024063-PA	56	Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553	"Separation of Sister Chromatids";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs"
EAFF004200-PA	24	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-437239	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Mitotic Prometaphase";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Recycling pathway of L1"
EAFF009598-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF013693-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF011409-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EAFF003521-PA	1	KEGG: 00970+6.1.1.5	"Aminoacyl-tRNA biosynthesis"
EAFF005487-PA	15	Reactome: R-HSA-1227986;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-9665251;Reactome: R-HSA-9665249;Reactome: R-HSA-9634285;Reactome: R-HSA-9665246;Reactome: R-HSA-8863795;Reactome: R-HSA-9665245;Reactome: R-HSA-9652282;Reactome: R-HSA-9665247;Reactome: R-HSA-9664565;Reactome: R-HSA-9665233;Reactome: R-HSA-1236382;Reactome: R-HSA-9665250	"Signaling by ERBB2";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to neratinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to tesevatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to AEE788"
EAFF005521-PA	52	Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-749476;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-8851708;Reactome: R-HSA-73762;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73980;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-168325	"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Transcription Initiation";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Termination";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis"
EAFF004472-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF014836-PA	5	MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
EAFF005394-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF001658-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF016800-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF014996-PA	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
EAFF011872-PA	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EAFF009139-PA	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease"
EAFF017201-PA	57	Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585	"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Ub-specific processing proteases";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G"
EAFF027585-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EAFF017291-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF020928-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EAFF016134-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EAFF003376-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF013264-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF000821-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EAFF016993-PA	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF003400-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF006429-PA	14	MetaCyc: PWY-5104;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5101;Reactome: R-HSA-70895;MetaCyc: PWY-5057;MetaCyc: PWY-5103;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5078;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42	"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"L-valine degradation II";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis";"L-leucine degradation III";"L-isoleucine degradation II";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation"
EAFF012148-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
EAFF012392-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
EAFF006884-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
EAFF011668-PA	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
EAFF009746-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF005280-PA	6	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling"
EAFF022876-PA	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
EAFF016545-PA	7	Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
EAFF017819-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF023318-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF010778-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF009730-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF016257-PA	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
EAFF016476-PA	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
EAFF014529-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
EAFF023337-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
EAFF020134-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EAFF021021-PA	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831	"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
EAFF027529-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF002916-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF019181-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF003454-PA	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
EAFF000559-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF006477-PA	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EAFF015188-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF009463-PA	4	Reactome: R-HSA-9616334;Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-110329	"Defective Base Excision Repair Associated with NEIL1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged pyrimidine"
EAFF015145-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EAFF025358-PA	19	MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation"
EAFF024288-PA	8	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy"
EAFF014414-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF001185-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EAFF000358-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
EAFF002690-PA	4	Reactome: R-HSA-70921;MetaCyc: PWY-5030;KEGG: 00340+4.3.1.3;MetaCyc: PWY-5028	"Histidine catabolism";"L-histidine degradation III";"Histidine metabolism";"L-histidine degradation II"
EAFF029427-PA	7	Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-6724	"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation II"
EAFF022348-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF000293-PA	2	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)"
EAFF015546-PA	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
EAFF010121-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
EAFF015827-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF021629-PA	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
EAFF013002-PA	6	Reactome: R-HSA-1474151;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-6983	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis"
EAFF019469-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF023319-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF019644-PA	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
EAFF020003-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF029584-PA	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
EAFF024292-PA	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
EAFF014993-PA	5	Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209543;Reactome: R-HSA-9020702	"NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes";"Interleukin-1 signaling"
EAFF007108-PA	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
EAFF027011-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF025058-PA	15	MetaCyc: PWY-6142;MetaCyc: PWY-2221;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycerol degradation to butanol"
EAFF009772-PA	17	KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-5532;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6611;MetaCyc: PWY-6608;Reactome: R-HSA-74259	"Purine metabolism";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Purine catabolism"
EAFF015232-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF018861-PA	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
EAFF027889-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF011201-PA	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
EAFF006375-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF006616-PA	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
EAFF005263-PA	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
EAFF016328-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF011933-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
EAFF025600-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF000018-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF028954-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
EAFF006613-PA	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
EAFF012287-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF015264-PA	5	MetaCyc: PWY-7185;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;Reactome: R-HSA-499943	"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
EAFF003850-PA	4	Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
EAFF020149-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF017876-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
EAFF013670-PA	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
EAFF019013-PA	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
EAFF012412-PA	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
EAFF003099-PA	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
EAFF024796-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EAFF012470-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF028967-PA	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
EAFF004502-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF014272-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
EAFF027957-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF027318-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF017260-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF005896-PA	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
EAFF002026-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EAFF011066-PA	14	Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-1632852;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation";"Intraflagellar transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Macroautophagy";"EML4 and NUDC in mitotic spindle formation"
EAFF021028-PA	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
EAFF019607-PA	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
EAFF014482-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
EAFF001078-PA	5	Reactome: R-HSA-532668;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis"
EAFF002974-PA	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
EAFF029481-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF017787-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
EAFF027485-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF008680-PA	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EAFF015646-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF012292-PA	14	MetaCyc: PWY-3781;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1	"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes"
EAFF008100-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF008133-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF007887-PA	3	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
EAFF003128-PA	12	Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-380320	"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes"
EAFF017076-PA	11	MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-3881;MetaCyc: PWY-7586	"Mannitol degradation II";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
EAFF006514-PA	5	KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32	"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis"
EAFF009302-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
EAFF000172-PA	4	Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14	"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism"
EAFF010359-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EAFF015742-PA	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation"
EAFF012601-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF014011-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
EAFF023256-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF011756-PA	1	Reactome: R-HSA-71064	"Lysine catabolism"
EAFF011988-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF017077-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
EAFF024509-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis"
EAFF024434-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
EAFF026011-PA	1	Reactome: R-HSA-5676934	"Protein repair"
EAFF019183-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF013802-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF013272-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF022260-PA	1	Reactome: R-HSA-1483148	"Synthesis of PG"
EAFF001499-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF004134-PA	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
EAFF023397-PA	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
EAFF001938-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF006117-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
EAFF016605-PA	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
EAFF028931-PA	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
EAFF028499-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EAFF004633-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EAFF026786-PA	11	Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-432040	"G alpha (z) signalling events";"PKA activation";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins"
EAFF026982-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF003560-PA	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
EAFF022261-PA	4	KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561	"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Choline biosynthesis III"
EAFF019343-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF005917-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF012883-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF021642-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
EAFF013131-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
EAFF018487-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EAFF022139-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF027605-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
EAFF022567-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF021841-PA	13	Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-8948216	"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Laminin interactions";"Anchoring fibril formation";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Extracellular matrix organization";"NCAM1 interactions";"Signaling by PDGF";"Collagen chain trimerization"
EAFF028062-PA	1	Reactome: R-HSA-1483148	"Synthesis of PG"
EAFF016352-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF024529-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
EAFF001307-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF022384-PA	13	MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-7254	"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)"
EAFF003322-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF005846-PA	16	MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-7218	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
EAFF020464-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EAFF012828-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF025435-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF019820-PA	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
EAFF019603-PA	56	Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323	"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling"
EAFF022046-PA	7	Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034	"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np"
EAFF017916-PA	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
EAFF026568-PA	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
EAFF016690-PA	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
EAFF001906-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF015081-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF012002-PA	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
EAFF019676-PA	56	Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761	"Degradation of GLI1 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling"
EAFF022879-PA	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
EAFF028329-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EAFF009019-PA	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
EAFF019831-PA	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
EAFF025752-PA	7	MetaCyc: PWY-4302;MetaCyc: PWY-5083;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781	"Aerobic respiration III (alternative oxidase pathway)";"NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis";"Respiratory electron transport";"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)"
EAFF009758-PA	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
EAFF011129-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
EAFF000631-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EAFF005795-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
EAFF027504-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF000274-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF017489-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EAFF025484-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF025143-PA	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
EAFF021515-PA	40	KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6945;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7401;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6883;MetaCyc: PWY-5789;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-5138;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-6944;MetaCyc: PWY-7654;MetaCyc: PWY-6583;MetaCyc: PWY-7656;MetaCyc: PWY-7779;MetaCyc: PWY-7726;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-5109;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00280+4.2.1.17+1.1.1.35	"Caprolactam degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"2-methylpropene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Benzoate degradation";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Fatty acid salvage";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Propanoate metabolism";"Tryptophan metabolism";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid elongation";"Limonene and pinene degradation";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to butanol I";"Spodoptera littoralis pheromone biosynthesis";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Toluene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Valine, leucine and isoleucine degradation"
EAFF011217-PA	5	KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation"
EAFF021010-PA	1	KEGG: 00970+6.1.1.15	"Aminoacyl-tRNA biosynthesis"
EAFF024912-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EAFF012783-PA	11	MetaCyc: PWY-5744;Reactome: R-HSA-3299685;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00480+1.11.1.15	"Glyoxylate assimilation";"Detoxification of Reactive Oxygen Species";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glutathione metabolism"
EAFF014493-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF012141-PA	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
EAFF017095-PA	7	MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
EAFF007704-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EAFF022353-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EAFF028129-PA	1	KEGG: 00040+5.3.1.4	"Pentose and glucuronate interconversions"
EAFF007968-PA	6	Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins"
EAFF011329-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF017798-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF003698-PA	8	Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
EAFF010654-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EAFF016232-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF011259-PA	4	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
EAFF002197-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF020329-PA	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism"
EAFF011313-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF015763-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
EAFF002844-PA	7	Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288	"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1"
EAFF024540-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF007122-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF007695-PA	29	Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-72086	"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"mRNA Capping"
EAFF022080-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
EAFF019923-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF012573-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
EAFF000022-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF027351-PA	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
EAFF002423-PA	10	Reactome: R-HSA-70171;MetaCyc: PWY-6886;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-5484	"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)"
EAFF026964-PA	11	Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942	"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)"
EAFF008828-PA	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
EAFF021858-PA	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
EAFF010427-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
EAFF023413-PA	12	Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-193692	"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR"
EAFF015736-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF024456-PA	11	MetaCyc: PWY-5123;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-7560;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-6383;MetaCyc: PWY-6174;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6859;MetaCyc: PWY-7102	"Trans, trans-farnesyl diphosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)"
EAFF005115-PA	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
EAFF021862-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF024803-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF026541-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF003983-PA	4	MetaCyc: PWY-5030;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5028;Reactome: R-HSA-70921	"L-histidine degradation III";"Histidine metabolism";"L-histidine degradation II";"Histidine catabolism"
EAFF021331-PA	10	MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-6549	"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III"
EAFF025434-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF007320-PA	6	MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
EAFF004731-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
EAFF027216-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
EAFF020712-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EAFF023481-PA	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation"
EAFF027338-PA	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
EAFF012212-PA	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
EAFF017573-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
EAFF001890-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EAFF003653-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF010849-PA	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
EAFF022789-PA	17	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
EAFF004924-PA	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
EAFF027894-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EAFF023325-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF001494-PA	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
EAFF010341-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF010540-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
EAFF023790-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF014762-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EAFF007836-PA	27	Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159227	"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA"
EAFF000802-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF004248-PA	20	Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110320	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH"
EAFF000987-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF018854-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF011941-PA	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
EAFF020309-PA	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
EAFF008086-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
EAFF023290-PA	6	MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
EAFF023209-PA	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape"
EAFF025939-PA	5	KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6	"Purine metabolism";"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism"
EAFF004984-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF018121-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010769-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EAFF009584-PA	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
EAFF001221-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EAFF010475-PA	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
EAFF014745-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF007121-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF000024-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF017718-PA	56	Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702	"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling"
EAFF004041-PA	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
EAFF013243-PA	4	MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
EAFF008088-PA	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
EAFF019901-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF010726-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF001846-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
EAFF010755-PA	9	MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2	"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis"
EAFF019892-PA	1	Reactome: R-HSA-140837	"Intrinsic Pathway of Fibrin Clot Formation"
EAFF009282-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF022177-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF006682-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF017479-PA	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
EAFF007665-PA	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
EAFF012494-PA	5	KEGG: 00983+2.7.1.21;KEGG: 00240+2.7.1.21;MetaCyc: PWY-7199;Reactome: R-HSA-69205;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine salvage"
EAFF005881-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF019503-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF014265-PA	5	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811434	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF019778-PA	6	Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569	"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
EAFF025851-PA	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
EAFF026386-PA	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
EAFF003926-PA	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
EAFF023125-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF017458-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
EAFF005800-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EAFF011586-PA	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
EAFF019014-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF014427-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
EAFF022930-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF002892-PA	17	Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176409	"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
EAFF022193-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EAFF021332-PA	10	KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-6549;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124	"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"L-glutamine biosynthesis III";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)"
EAFF022386-PA	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
EAFF020085-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF015743-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF001756-PA	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
EAFF014950-PA	16	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EAFF024960-PA	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
EAFF013427-PA	19	Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244	"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Ion homeostasis";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation"
EAFF026852-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF010555-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF027461-PA	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
EAFF009104-PA	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
EAFF023679-PA	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
EAFF011841-PA	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
EAFF026021-PA	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
EAFF003625-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF008030-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF023988-PA	18	Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167200	"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
EAFF025136-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF010936-PA	10	MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose catabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
EAFF006641-PA	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
EAFF021468-PA	9	Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-3560783	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type"
EAFF003065-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
EAFF016673-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF012933-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
EAFF015437-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EAFF025252-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF004216-PA	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
EAFF019601-PA	4	MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27	"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation"
EAFF011488-PA	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis"
EAFF025301-PA	1	MetaCyc: PWY-7802	"N-end rule pathway II (prokaryotic)"
EAFF004111-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EAFF027891-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
EAFF024255-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF017490-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
EAFF011251-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
EAFF021244-PA	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
EAFF009441-PA	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
EAFF006467-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF028511-PA	10	KEGG: 00720+2.7.2.1;KEGG: 00640+2.7.2.1;MetaCyc: PWY-5497;KEGG: 00430+2.7.2.1;KEGG: 00620+2.7.2.1;KEGG: 00680+2.7.2.1;MetaCyc: PWY-8015;MetaCyc: PWY-8086;MetaCyc: PWY-5485;MetaCyc: PWY-5482	"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Purine nucleobases degradation II (anaerobic)";"Taurine and hypotaurine metabolism";"Pyruvate metabolism";"Methane metabolism";"Glycine degradation (Stickland reaction)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to acetate IV";"Pyruvate fermentation to acetate II"
EAFF018942-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF000442-PA	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
EAFF005792-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF005020-PA	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EAFF029101-PA	5	Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110329	"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine"
EAFF016503-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
EAFF012512-PA	10	Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1	"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis"
EAFF000258-PA	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
EAFF012773-PA	16	Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174184	"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
EAFF009514-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF021467-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF002695-PA	8	KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Galactose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
EAFF006343-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EAFF005424-PA	11	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes"
EAFF007203-PA	14	MetaCyc: PWY-2201;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1	"Folate transformations I";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Folate polyglutamylation";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"One carbon pool by folate";"Photorespiration ";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism"
EAFF010720-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF025887-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF015904-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF014541-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF005655-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
EAFF000791-PA	6	Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-201722	"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex"
EAFF011235-PA	4	MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
EAFF004083-PA	5	Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210	"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
EAFF001130-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF023633-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EAFF005658-PA	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
EAFF018235-PA	6	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-72163	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"mRNA Splicing - Major Pathway"
EAFF013590-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
EAFF007955-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF003869-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
EAFF007161-PA	18	MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
EAFF001384-PA	33	Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-5578749	"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Transcriptional regulation by small RNAs"
EAFF000030-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF021307-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF004886-PA	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
EAFF018465-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
EAFF024178-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
EAFF000716-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF009084-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
EAFF006245-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EAFF011623-PA	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
EAFF011120-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF020878-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF027484-PA	1	Reactome: R-HSA-419771	"Opsins"
EAFF022614-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
EAFF013203-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF002832-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF017765-PA	19	Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275	"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"LDL clearance";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"VLDL assembly";"Chylomicron remodeling";"Chylomicron clearance";"Post-translational protein phosphorylation"
EAFF007486-PA	8	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF010307-PA	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF022005-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF021814-PA	6	Reactome: R-HSA-913709;Reactome: R-HSA-5083625;Reactome: R-HSA-977068;Reactome: R-HSA-5083632;Reactome: R-HSA-5083636;Reactome: R-HSA-5621480	"O-linked glycosylation of mucins";"Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)";"Termination of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Defective GALNT12 causes colorectal cancer 1 (CRCS1)";"Dectin-2 family"
EAFF009022-PA	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
EAFF012171-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF009961-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
EAFF006734-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF015306-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF024954-PA	5	MetaCyc: PWY-7328;MetaCyc: PWY-6397;KEGG: 00052+5.4.99.9;MetaCyc: PWY-7622;KEGG: 00520+5.4.99.9	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"UDP-alpha-D-galactofuranose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
EAFF028495-PA	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
EAFF003512-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
EAFF011347-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
EAFF005178-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF010832-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010963-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EAFF003960-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF011847-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF004747-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF024601-PA	4	Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane"
EAFF011651-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF015896-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
EAFF020138-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF000605-PA	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
EAFF026282-PA	7	Reactome: R-HSA-180746;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168333	"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery"
EAFF017946-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
EAFF010078-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF003201-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
EAFF014864-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF015276-PA	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
EAFF009642-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
EAFF023726-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EAFF014334-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF006832-PA	5	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate"
EAFF006025-PA	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
EAFF005622-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
EAFF001416-PA	4	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Unwinding of DNA"
EAFF028382-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EAFF006737-PA	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
EAFF018137-PA	4	KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849;MetaCyc: PWY-5691;MetaCyc: PWY-7394	"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Urate conversion to allantoin II"
EAFF004013-PA	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
EAFF008599-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EAFF010850-PA	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
EAFF009097-PA	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
EAFF006686-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EAFF022176-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF015632-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EAFF026817-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF013206-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
EAFF013996-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
EAFF007170-PA	10	MetaCyc: PWY-5891;MetaCyc: PWY-5849;MetaCyc: PWY-5890;MetaCyc: PWY-5844;MetaCyc: PWY-7996;MetaCyc: PWY-5892;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163	"Menaquinol-11 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis"
EAFF022938-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF004893-PA	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
EAFF023322-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF019283-PA	12	MetaCyc: PWY-6728;KEGG: 00630+6.4.1.3;MetaCyc: PWY-5743;Reactome: R-HSA-71032;MetaCyc: PWY-7384;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.3;MetaCyc: PWYG-321;MetaCyc: PWY-5789;KEGG: 00280+6.4.1.3;Reactome: R-HSA-3371599;KEGG: 00640+6.4.1.3	"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"3-hydroxypropanoate cycle";"Propionyl-CoA catabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Defective HLCS causes multiple carboxylase deficiency";"Propanoate metabolism"
EAFF006194-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
EAFF022426-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF000308-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF015099-PA	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
EAFF018445-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF023466-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF028334-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF028788-PA	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
EAFF021031-PA	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
EAFF000808-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF022832-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EAFF022047-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
EAFF001887-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF022287-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
EAFF006320-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
EAFF021559-PA	4	MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
EAFF018075-PA	1	Reactome: R-HSA-189451	"Heme biosynthesis"
EAFF000425-PA	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
EAFF019687-PA	5	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
EAFF029300-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EAFF024180-PA	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF006347-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EAFF025880-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF011135-PA	10	Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-72706	"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF013468-PA	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
EAFF019285-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF004629-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EAFF013452-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EAFF014833-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF017678-PA	20	MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism"
EAFF011970-PA	20	Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756	"Dual Incision in GG-NER";"Polymerase switching";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation"
EAFF011533-PA	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
EAFF011671-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EAFF008587-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
EAFF013457-PA	7	KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;MetaCyc: PWY-5921	"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
EAFF007630-PA	8	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
EAFF020245-PA	9	MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675	"Ammonia assimilation cycle II";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)"
EAFF001573-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF003530-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF020467-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EAFF028968-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF003093-PA	7	Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
EAFF024575-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EAFF019630-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis"
EAFF021586-PA	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
EAFF029228-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF017229-PA	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
EAFF017328-PA	4	MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737	"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis"
EAFF006224-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF005988-PA	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
EAFF018564-PA	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
EAFF002940-PA	1	Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH2"
EAFF017487-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
EAFF023789-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF000299-PA	4	Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism"
EAFF010770-PA	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
EAFF014542-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF018884-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF024600-PA	4	Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-6799198	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis"
EAFF003526-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF011436-PA	5	Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897	"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes"
EAFF008440-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF021609-PA	4	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
EAFF012290-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EAFF016057-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF014190-PA	6	MetaCyc: PWY-6505;MetaCyc: PWY-5651;MetaCyc: PWY-6309;MetaCyc: PWY-5647;Reactome: R-HSA-71240;KEGG: 00380+1.13.11.6	"L-tryptophan degradation XII (Geobacillus)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"2-nitrobenzoate degradation I";"Tryptophan catabolism";"Tryptophan metabolism"
EAFF015907-PA	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
EAFF023841-PA	52	Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73980;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-5578749;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-6807505	"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Transcriptional regulation by small RNAs";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes"
EAFF006379-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF003375-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF024193-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF002833-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF027638-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF011271-PA	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
EAFF021016-PA	5	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate"
EAFF021809-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
EAFF023559-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EAFF018789-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EAFF018610-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF015178-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF008424-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
EAFF020376-PA	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
EAFF003088-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
EAFF008749-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF003904-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF006405-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF024793-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EAFF017340-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EAFF014687-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF004587-PA	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
EAFF029394-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF029169-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF023329-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF000871-PA	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
EAFF000257-PA	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
EAFF015163-PA	12	Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862	"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
EAFF008785-PA	1	Reactome: R-HSA-446193	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
EAFF004137-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF013597-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
EAFF012973-PA	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism"
EAFF023468-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF004211-PA	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
EAFF017003-PA	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
EAFF000731-PA	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
EAFF009686-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EAFF012201-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
EAFF012948-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF026741-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EAFF004342-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EAFF000724-PA	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
EAFF013832-PA	24	Reactome: R-HSA-5218920;Reactome: R-HSA-354192;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;Reactome: R-HSA-114604;Reactome: R-HSA-392451;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-202424;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357	"VEGFR2 mediated vascular permeability";"Integrin signaling";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"GPVI-mediated activation cascade";"G beta:gamma signalling through PI3Kgamma";"RSK activation";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Downstream TCR signaling";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"Human papillomavirus infection";"RHO GTPases activate PKNs";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"Activation of AKT2";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling"
EAFF013287-PA	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF016669-PA	3	Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67;Reactome: R-HSA-156581	"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes";"Methylation"
EAFF010137-PA	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
EAFF013053-PA	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation"
EAFF000178-PA	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
EAFF021447-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
EAFF026177-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF028894-PA	1	Reactome: R-HSA-196757	"Metabolism of folate and pterines"
EAFF009494-PA	5	Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
EAFF022498-PA	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
EAFF012540-PA	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
EAFF003613-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EAFF013827-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
EAFF005517-PA	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
EAFF019136-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
EAFF005787-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF004662-PA	1	KEGG: 00760+1.4.1.21	"Nicotinate and nicotinamide metabolism"
EAFF028752-PA	10	MetaCyc: PWY-7571;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7391	"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)"
EAFF012932-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
EAFF026974-PA	9	Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer"
EAFF009674-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
EAFF019787-PA	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
EAFF014943-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EAFF023924-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
EAFF027437-PA	40	Reactome: R-HSA-6782135;Reactome: R-HSA-5617472;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-167290	"Dual incision in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation"
EAFF023734-PA	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III"
EAFF021574-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EAFF028617-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
EAFF009187-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF014116-PA	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
EAFF026844-PA	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EAFF002711-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF015954-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EAFF022415-PA	12	Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
EAFF009458-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
EAFF021620-PA	1	Reactome: R-HSA-1483101	"Synthesis of PS"
EAFF012179-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
EAFF024640-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF014875-PA	52	Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556	"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RAS by GAPs";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport"
EAFF011625-PA	3	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes"
EAFF013560-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF021860-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EAFF006550-PA	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
EAFF016190-PA	19	KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;Reactome: R-HSA-163765;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"C5-Branched dibasic acid metabolism";"Neutrophil degranulation";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
EAFF002858-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF018016-PA	24	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EAFF001300-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF022911-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
EAFF023324-PA	12	Reactome: R-HSA-982772;Reactome: R-HSA-2894862;Reactome: R-HSA-5362798;Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-193692;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985	"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"TNF signaling";"Signaling by EGFR";"Regulated proteolysis of p75NTR";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4"
EAFF020936-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF003778-PA	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
EAFF003519-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF007986-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
EAFF012506-PA	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
EAFF013695-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF021241-PA	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
EAFF023977-PA	6	MetaCyc: PWY-5497;Reactome: R-HSA-70921;KEGG: 00670+2.1.2.5;KEGG: 00340+2.1.2.5;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030	"Purine nucleobases degradation II (anaerobic)";"Histidine catabolism";"One carbon pool by folate";"Histidine metabolism";"One carbon pool by folate";"L-histidine degradation III"
EAFF000948-PA	8	Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-212300	"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA"
EAFF002717-PA	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
EAFF008732-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF005360-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF000671-PA	4	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Synthesis of diphthamide-EEF2"
EAFF002904-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
EAFF003765-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EAFF028610-PA	2	MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31	"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
EAFF004985-PA	1	Reactome: R-HSA-1483101	"Synthesis of PS"
EAFF025653-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF014168-PA	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
EAFF009694-PA	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
EAFF000629-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF017685-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF029538-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
EAFF001086-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF018459-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF001561-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
EAFF013617-PA	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
EAFF018688-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF029530-PA	14	Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408	"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation"
EAFF006066-PA	6	Reactome: R-HSA-1433559;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-1433557	"Regulation of KIT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Signaling by SCF-KIT"
EAFF002135-PA	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
EAFF001120-PA	17	Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1	"Purine catabolism";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis";"Purine metabolism"
EAFF015895-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF021407-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EAFF024308-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EAFF017065-PA	1	Reactome: R-HSA-3295583	"TRP channels"
EAFF023735-PA	1	Reactome: R-HSA-5676934	"Protein repair"
EAFF010423-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
EAFF001032-PA	27	Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531	"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus"
EAFF029186-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
EAFF005621-PA	4	MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-8876198;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"RAB GEFs exchange GTP for GDP on RABs";"Lipoic acid metabolism"
EAFF026432-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF019248-PA	27	Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-5619107	"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
EAFF008780-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
EAFF002242-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EAFF019976-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
EAFF006027-PA	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF024641-PA	1	Reactome: R-HSA-264876	"Insulin processing"
EAFF028406-PA	1	Reactome: R-HSA-525793	"Myogenesis"
EAFF021544-PA	5	Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209543	"NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"p75NTR recruits signalling complexes"
EAFF024061-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
EAFF024699-PA	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
EAFF028964-PA	8	Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
EAFF008947-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
EAFF004479-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EAFF020659-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF005103-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
EAFF013654-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF018565-PA	7	Reactome: R-HSA-5578999;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling"
EAFF013451-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EAFF022898-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
EAFF008975-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF028778-PA	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
EAFF002450-PA	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
EAFF005614-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EAFF022273-PA	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
EAFF012238-PA	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
EAFF000256-PA	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
EAFF016870-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF014944-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EAFF023326-PA	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
EAFF020623-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF021953-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF022762-PA	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
EAFF001212-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
EAFF005885-PA	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
EAFF028390-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EAFF024490-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis"
EAFF022023-PA	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
EAFF008373-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF001012-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF011466-PA	18	KEGG: 00950+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115	"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
EAFF021333-PA	10	KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124	"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)"
EAFF021810-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
EAFF016616-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF015439-PA	5	Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-5689603	"Iron uptake and transport";"Neddylation";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases"
EAFF006020-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF019726-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EAFF029349-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF013050-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF019123-PA	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
EAFF008808-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF019185-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
EAFF002908-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF013755-PA	15	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-9603505;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167242	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat"
EAFF020316-PA	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
EAFF016474-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
EAFF019742-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
EAFF021045-PA	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
EAFF017539-PA	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
EAFF011680-PA	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
EAFF017778-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EAFF019003-PA	3	Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2	"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism"
EAFF004305-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF017626-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF006794-PA	2	Reactome: R-HSA-5576890;Reactome: R-HSA-5576893	"Phase 3 - rapid repolarisation";"Phase 2 - plateau phase"
EAFF003380-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF000449-PA	8	Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
EAFF000224-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF024499-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
EAFF022081-PA	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
EAFF006529-PA	42	Reactome: R-HSA-3214841;Reactome: R-HSA-3214842;Reactome: R-HSA-73728;Reactome: R-HSA-912446;Reactome: R-HSA-3214858;Reactome: R-HSA-427359;Reactome: R-HSA-4551638;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-110329;Reactome: R-HSA-5250924;Reactome: R-HSA-3214815;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-5625886;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-9616222;Reactome: R-HSA-5578749;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-110331	"PKMTs methylate histone lysines";"HDMs demethylate histones";"RNA Polymerase I Promoter Opening";"Meiotic recombination";"RMTs methylate histone arginines";"SIRT1 negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged pyrimidine";"B-WICH complex positively regulates rRNA expression";"HDACs deacetylate histones";"HATs acetylate histones";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"Transcriptional regulation by small RNAs";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged purine"
EAFF002949-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF021818-PA	6	Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
EAFF013852-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
EAFF003900-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF001028-PA	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
EAFF021026-PA	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
EAFF010036-PA	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
EAFF000075-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
EAFF021357-PA	2	MetaCyc: PWY-7286;Reactome: R-HSA-6782861	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
EAFF026441-PA	3	Reactome: R-HSA-194313;Reactome: R-HSA-195399;Reactome: R-HSA-114608	"VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation"
EAFF004244-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
EAFF016097-PA	52	Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-73776;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-5601884;Reactome: R-HSA-6781823;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-8851708;Reactome: R-HSA-76042;Reactome: R-HSA-203927;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-749476;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-6782135	"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"MicroRNA (miRNA) biogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Dual incision in TC-NER"
EAFF020265-PA	14	KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
EAFF012534-PA	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
EAFF025148-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF006309-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
EAFF003072-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EAFF024959-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
EAFF011287-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF010138-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
EAFF000267-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
EAFF029456-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF015044-PA	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
EAFF017359-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
EAFF001431-PA	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
EAFF015342-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EAFF017590-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EAFF000181-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
EAFF016406-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EAFF008298-PA	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
EAFF005359-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF021414-PA	16	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF015764-PA	7	MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
EAFF024838-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
EAFF008220-PA	3	Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271	"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
EAFF013323-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
EAFF013080-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF014816-PA	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
EAFF000435-PA	6	Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039	"Synthesis of PG";"Choline biosynthesis III";"Synthesis of PA";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
EAFF022382-PA	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
EAFF001599-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
EAFF014795-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
EAFF022976-PA	8	KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171	"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis"
EAFF000530-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF018631-PA	5	Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation"
EAFF014526-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF007148-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF005198-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF003059-PA	29	Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-3371511;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169	"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"HSF1 activation";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Termination of translesion DNA synthesis"
EAFF028908-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF006097-PA	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
EAFF006649-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF019177-PA	2	KEGG: 00450+1.8.1.9;Reactome: R-HSA-499943	"Selenocompound metabolism";"Interconversion of nucleotide di- and triphosphates"
EAFF024805-PA	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
EAFF021771-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF023049-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF012317-PA	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
EAFF022130-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
EAFF022467-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF021705-PA	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
EAFF015082-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF025825-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
EAFF006595-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF006009-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
EAFF015855-PA	4	KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
EAFF019743-PA	8	Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867	"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex"
EAFF001570-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF014095-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF003730-PA	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
EAFF001763-PA	7	Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897	"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes"
EAFF002669-PA	7	MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism"
EAFF011870-PA	5	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EAFF000572-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF004190-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EAFF021169-PA	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
EAFF015438-PA	10	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6807505	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes"
EAFF007893-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
EAFF001512-PA	19	Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901	"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"VLDL clearance";"LDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Scavenging by Class H Receptors";"Chylomicron clearance";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"Chylomicron assembly";"Platelet sensitization by LDL";"VLDL assembly";"Chylomicron remodeling"
EAFF003915-PA	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
EAFF012918-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF015022-PA	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
EAFF006196-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF006728-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
EAFF018328-PA	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
EAFF018017-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
EAFF003967-PA	10	KEGG: 00670+2.1.1.45;KEGG: 00240+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7199;Reactome: R-HSA-69205	"One carbon pool by folate";"Pyrimidine metabolism";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription"
EAFF005175-PA	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
EAFF025507-PA	2	MetaCyc: PWY-7379;MetaCyc: PWY-7375	"Mrna capping II";"Mrna capping I"
EAFF002492-PA	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
EAFF011142-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EAFF008087-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010319-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
EAFF021728-PA	1	Reactome: R-HSA-1483166	"Synthesis of PA"
EAFF005864-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF012293-PA	27	Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531	"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus"
EAFF015500-PA	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
EAFF017092-PA	9	MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789	"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
EAFF025707-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF029495-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF014111-PA	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
EAFF027171-PA	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
EAFF000466-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EAFF002633-PA	26	Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-5663220	"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Kinesins";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins"
EAFF014430-PA	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
EAFF023208-PA	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
EAFF020151-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
EAFF022381-PA	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
EAFF003106-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF025298-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
EAFF016331-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF010724-PA	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
EAFF006178-PA	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
EAFF003158-PA	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
EAFF028834-PA	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
EAFF016404-PA	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
EAFF003031-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF020942-PA	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
EAFF002603-PA	5	Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399	"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs";"Aggrephagy"
EAFF004154-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EAFF025446-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF024335-PA	42	Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-427413;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-5625886;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-5578749;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-5250924;Reactome: R-HSA-3214815;Reactome: R-HSA-5693565;Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-110330;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-5334118;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-3214858;Reactome: R-HSA-427359;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-3214842;Reactome: R-HSA-73728;Reactome: R-HSA-912446	"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"NoRC negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation by small RNAs";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"HATs acetylate histones";"HCMV Late Events";"B-WICH complex positively regulates rRNA expression";"HDACs deacetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA methylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RMTs methylate histone arginines";"SIRT1 negatively regulates rRNA expression";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"HDMs demethylate histones";"RNA Polymerase I Promoter Opening";"Meiotic recombination"
EAFF027274-PA	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
EAFF002454-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
EAFF021426-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF024049-PA	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
EAFF011573-PA	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
EAFF000673-PA	3	Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway"
EAFF024048-PA	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737	"Starch and sucrose metabolism";"Starch degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V"
EAFF021773-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
EAFF012709-PA	5	MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35	"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism"
EAFF004092-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF002292-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF014314-PA	4	MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50	"Spermidine biosynthesis III";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
EAFF004310-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF004478-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EAFF009896-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
EAFF014264-PA	2	KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
EAFF002917-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EAFF006408-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF016074-PA	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
EAFF026504-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF015112-PA	17	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7224	"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage"
EAFF009372-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF021970-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
EAFF028251-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
EAFF018751-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation"
EAFF006123-PA	13	KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-5132;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118	"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Ethanol oxidation";"Lupulone and humulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol"
EAFF000837-PA	1	KEGG: 00500+2.4.1.15	"Starch and sucrose metabolism"
EAFF000834-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF015013-PA	4	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases"
EAFF025708-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF013003-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF005415-PA	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275	"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"VLDL clearance";"Regulation of TLR by endogenous ligand";"LDL clearance";"Scavenging by Class H Receptors";"LDL remodeling";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Chylomicron remodeling";"Chylomicron assembly";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Chylomicron clearance";"Post-translational protein phosphorylation"
EAFF004722-PA	30	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-198323;Reactome: R-HSA-8876198;Reactome: R-HSA-1358803;Reactome: R-HSA-111447;Reactome: R-HSA-198693;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-389513;KEGG: 04150+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-6804759;Reactome: R-HSA-5218920;Reactome: R-HSA-6804758;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1257604;Reactome: R-HSA-8941332;KEGG: 05170+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-392451	"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Regulation of PTEN stability and activity";"AKT phosphorylates targets in the cytosol";"RAB GEFs exchange GTP for GDP on RABs";"Downregulation of ERBB2:ERBB3 signaling";"Activation of BAD and translocation to mitochondria";"AKT phosphorylates targets in the nucleus";"Human papillomavirus infection";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"CTLA4 inhibitory signaling";"mTOR signaling pathway";"AKT-mediated inactivation of FOXO1A";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of TP53 Activity through Association with Co-factors";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Activity through Acetylation";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"PIP3 activates AKT signaling";"RUNX2 regulates genes involved in cell migration";"Human immunodeficiency virus 1 infection";"Negative regulation of the PI3K/AKT network";"G beta:gamma signalling through PI3Kgamma"
EAFF001531-PA	25	Reactome: R-HSA-8941284;Reactome: R-HSA-9018519;Reactome: R-HSA-8939902;Reactome: R-HSA-8934593;Reactome: R-HSA-8951936;Reactome: R-HSA-8941333;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8931987;Reactome: R-HSA-8940973;Reactome: R-HSA-8877330;Reactome: R-HSA-8939236;Reactome: R-HSA-8939246;Reactome: R-HSA-8939245;Reactome: R-HSA-8941326;Reactome: R-HSA-8939247;Reactome: R-HSA-9616222;Reactome: R-HSA-8941858;Reactome: R-HSA-8941332;Reactome: R-HSA-8939256;Reactome: R-HSA-8951911;Reactome: R-HSA-8949275;Reactome: R-HSA-8935964;Reactome: R-HSA-8878166;Reactome: R-HSA-8936459	"RUNX2 regulates chondrocyte maturation";"Estrogen-dependent gene expression";"Regulation of RUNX2 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX3 regulates p14-ARF";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates osteoblast differentiation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX3 expression and activity";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates expression of components of tight junctions";"Transcriptional regulation by RUNX2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
EAFF001543-PA	3	Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases"
EAFF006338-PA	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
EAFF004870-PA	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
EAFF017781-PA	4	Reactome: R-HSA-937039;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling"
EAFF020147-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF011134-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
EAFF001862-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
EAFF002620-PA	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
EAFF019900-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF012093-PA	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
EAFF006125-PA	5	KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism"
EAFF014176-PA	3	Reactome: R-HSA-194313;Reactome: R-HSA-195399;Reactome: R-HSA-114608	"VEGF ligand-receptor interactions";"VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation"
EAFF009722-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF002606-PA	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
EAFF021226-PA	10	MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112	"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification"
EAFF027704-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EAFF023146-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
EAFF003169-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
EAFF012252-PA	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
EAFF011319-PA	14	Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-75955	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation"
EAFF012306-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
EAFF005063-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
EAFF018105-PA	1	Reactome: R-HSA-140837	"Intrinsic Pathway of Fibrin Clot Formation"
EAFF013658-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF000471-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF014273-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
EAFF027479-PA	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
EAFF010586-PA	8	KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11	"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis"
EAFF009162-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
EAFF019650-PA	9	Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-416476	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events"
EAFF020485-PA	13	KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"CS/DS degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
EAFF020465-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EAFF027214-PA	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
EAFF000007-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF011798-PA	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
EAFF024493-PA	16	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF020887-PA	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-606279	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere"
EAFF022413-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF023478-PA	3	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
EAFF008470-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF025254-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF004759-PA	4	MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040	"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis"
EAFF004158-PA	5	Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619	"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN"
EAFF027719-PA	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF008094-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF011871-PA	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EAFF026685-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF010429-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF027660-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF004935-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF022137-PA	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF002636-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF022065-PA	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
EAFF024109-PA	3	Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation"
EAFF027395-PA	5	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-201722	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex"
EAFF009492-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF005250-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF028918-PA	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
EAFF007840-PA	7	MetaCyc: PWY-7841;MetaCyc: PWY-7839;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-5129	"Neolacto-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)"
EAFF004732-PA	26	Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-6804114;Reactome: R-HSA-4615885;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-69205;Reactome: R-HSA-5358565;Reactome: R-HSA-8866654;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-174414;Reactome: R-HSA-1362277;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-174417;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-110314	"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SUMOylation of DNA replication proteins";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G1/S-Specific Transcription";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"E3 ubiquitin ligases ubiquitinate target proteins";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Processive synthesis on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex"
EAFF007615-PA	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
EAFF017827-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
EAFF007587-PA	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
EAFF029184-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EAFF014763-PA	10	Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111457	"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria"
EAFF021779-PA	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
EAFF014003-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EAFF002795-PA	27	Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854	"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly"
EAFF008622-PA	6	MetaCyc: PWY-5789;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6722	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Candicidin biosynthesis"
EAFF013114-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF008372-PA	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
EAFF028200-PA	9	KEGG: 00400+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism"
EAFF004400-PA	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
EAFF027492-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EAFF020702-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EAFF013616-PA	7	Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
EAFF010736-PA	6	MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6722	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis"
EAFF028624-PA	2	KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004	"Pentose phosphate pathway";"Entner-Doudoroff pathway I"
EAFF002703-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
EAFF017029-PA	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6	"Chitin derivatives degradation";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
EAFF026788-PA	11	Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418597	"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"G alpha (s) signalling events";"Purine metabolism";"PKA activation";"G alpha (z) signalling events"
EAFF011257-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF004256-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EAFF011437-PA	5	Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy"
EAFF009348-PA	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
EAFF008477-PA	56	Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-2467813	"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Orc1 removal from chromatin";"Separation of Sister Chromatids"
EAFF006619-PA	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
EAFF019017-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EAFF025913-PA	6	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock"
EAFF012150-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
EAFF016938-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF004066-PA	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
EAFF019140-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF029303-PA	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
EAFF004113-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EAFF008797-PA	3	Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
EAFF014901-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF020797-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF007355-PA	11	Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507	"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
EAFF006119-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
EAFF010223-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
EAFF011138-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
EAFF023058-PA	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
EAFF000788-PA	6	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
EAFF017084-PA	12	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417	"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
EAFF014681-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF003381-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF017147-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF010951-PA	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
EAFF019024-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EAFF000578-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
EAFF012912-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF025265-PA	9	MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
EAFF006615-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF021146-PA	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
EAFF018776-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF017211-PA	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
EAFF011620-PA	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
EAFF017217-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EAFF011647-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
EAFF017322-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF007783-PA	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
EAFF008344-PA	7	MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
EAFF005803-PA	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
EAFF025881-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF024165-PA	4	MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
EAFF003668-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
EAFF017687-PA	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
EAFF008178-PA	5	Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-5689603	"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"Neddylation";"Iron uptake and transport";"UCH proteinases"
EAFF001213-PA	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
EAFF000567-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF025417-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EAFF019606-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF007424-PA	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"mTOR signaling pathway"
EAFF004009-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EAFF018457-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF008217-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EAFF004197-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
EAFF010241-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF002980-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
EAFF006634-PA	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
EAFF002518-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling"
EAFF028814-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF000556-PA	7	Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends"
EAFF013831-PA	9	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
EAFF020120-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EAFF003005-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
EAFF004070-PA	11	Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-72163	"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"mRNA Splicing - Major Pathway"
EAFF022127-PA	1	Reactome: R-HSA-1483148	"Synthesis of PG"
EAFF017843-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
EAFF018458-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF000844-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
EAFF006352-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF023482-PA	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801	"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS"
EAFF018788-PA	5	MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
EAFF018255-PA	3	Reactome: R-HSA-70263;Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Gluconeogenesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
EAFF004488-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF012040-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF018101-PA	3	Reactome: R-HSA-156590;MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12	"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism"
EAFF005279-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF017851-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF000765-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
EAFF014394-PA	6	KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36	"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
EAFF026257-PA	18	KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7383;MetaCyc: PWY-5392;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690	"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)"
EAFF006691-PA	7	Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
EAFF003194-PA	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
EAFF024516-PA	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
EAFF021863-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF000038-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
EAFF017365-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
EAFF026249-PA	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
EAFF025885-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF009707-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF000869-PA	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF002893-PA	8	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2"
EAFF011327-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF026015-PA	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
EAFF017699-PA	5	Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662	"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Glycosphingolipid metabolism"
EAFF011049-PA	2	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
EAFF002505-PA	4	KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
EAFF017099-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF005939-PA	1	KEGG: 00970+6.1.1.1	"Aminoacyl-tRNA biosynthesis"
EAFF014715-PA	6	Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species"
EAFF000100-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
EAFF014954-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
EAFF025553-PA	4	MetaCyc: PWY-6823;MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12	"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
EAFF017166-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EAFF003806-PA	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
EAFF025508-PA	2	MetaCyc: PWY-7379;MetaCyc: PWY-7375	"Mrna capping II";"Mrna capping I"
EAFF020150-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
EAFF029085-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
EAFF008590-PA	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
EAFF005533-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF017044-PA	5	Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation"
EAFF019348-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF017174-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF005317-PA	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
EAFF003684-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EAFF018307-PA	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
EAFF008689-PA	6	MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6749	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"CMP-legionaminate biosynthesis I"
EAFF023230-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EAFF021698-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
EAFF027498-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF001716-PA	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
EAFF017874-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
EAFF018697-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
EAFF013614-PA	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
EAFF027345-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EAFF017848-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
EAFF002414-PA	1	Reactome: R-HSA-525793	"Myogenesis"
EAFF022393-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF007590-PA	16	Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EAFF029196-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF017391-PA	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
EAFF025706-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF005299-PA	6	KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22	"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism"
EAFF027992-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
EAFF003990-PA	11	Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-381340	"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Generic Transcription Pathway";"RORA activates gene expression";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation"
EAFF021466-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF022218-PA	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
EAFF008740-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF009739-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
EAFF008756-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
EAFF007607-PA	27	Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-191859	"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"snRNP Assembly"
EAFF013453-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EAFF012202-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
EAFF006817-PA	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
EAFF010116-PA	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
EAFF017878-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
EAFF027457-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
EAFF028081-PA	1	Reactome: R-HSA-5578775	"Ion homeostasis"
EAFF026888-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
EAFF021762-PA	5	Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695	"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neutrophil degranulation"
EAFF017234-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
EAFF001922-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF027522-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF024383-PA	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
EAFF020632-PA	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985	"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose"
EAFF008642-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF004453-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF022022-PA	12	KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9	"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions"
EAFF005649-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EAFF018883-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF025247-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF017491-PA	14	Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110320	"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching";"Translesion Synthesis by POLH"
EAFF021294-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
EAFF001417-PA	8	Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166	"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate"
EAFF002752-PA	11	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Human papillomavirus infection";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation"
EAFF005013-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EAFF006688-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF012490-PA	11	Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436	"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic"
EAFF007556-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EAFF021296-PA	3	MetaCyc: PWY-5941;Reactome: R-HSA-70221;KEGG: 00500+3.2.1.3	"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism"
EAFF024439-PA	3	Reactome: R-HSA-194313;Reactome: R-HSA-114608;Reactome: R-HSA-195399	"VEGF ligand-receptor interactions";"Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization"
EAFF005850-PA	3	Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation"
EAFF018213-PA	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
EAFF002049-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF017944-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
EAFF004318-PA	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
EAFF008585-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF001740-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF017645-PA	1	Reactome: R-HSA-74217	"Purine salvage"
EAFF019727-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
EAFF014440-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF012277-PA	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA"
EAFF017788-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
EAFF005674-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF005941-PA	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
EAFF002973-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EAFF029156-PA	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
EAFF016342-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF023826-PA	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
EAFF013466-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
EAFF011634-PA	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
EAFF006656-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF018265-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF023182-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF005788-PA	6	MetaCyc: PWY-6722;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5789	"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle"
EAFF004750-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
EAFF002452-PA	5	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway"
EAFF003708-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF017517-PA	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
EAFF026965-PA	11	Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-5696400	"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Dual Incision in GG-NER"
EAFF022416-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF025483-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
EAFF015146-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF003826-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF016507-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF010651-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF004580-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
EAFF023849-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EAFF012962-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF005149-PA	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
EAFF016273-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF009986-PA	1	Reactome: R-HSA-6783984	"Glycine degradation"
EAFF004079-PA	5	Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
EAFF021217-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF014043-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010351-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
EAFF003060-PA	29	Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756	"Translesion synthesis by REV1";"Dual Incision in GG-NER";"HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation"
EAFF003916-PA	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
EAFF000163-PA	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
EAFF023673-PA	26	Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497	"Recycling pathway of L1";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Gap junction assembly";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
EAFF020665-PA	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling"
EAFF009057-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EAFF021341-PA	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
EAFF000337-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF024762-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EAFF015381-PA	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
EAFF008891-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF000137-PA	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
EAFF005552-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
EAFF025925-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
EAFF004593-PA	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
EAFF015667-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF005603-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF001914-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF003919-PA	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
EAFF001635-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
EAFF000360-PA	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
EAFF008126-PA	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
EAFF005785-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF009962-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EAFF006829-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF009996-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EAFF000621-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF004728-PA	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
EAFF014683-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF003862-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EAFF027218-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
EAFF021730-PA	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
EAFF028980-PA	24	Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-983189	"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Aggrephagy";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"MHC class II antigen presentation";"Mitotic Prometaphase";"Kinesins"
EAFF008223-PA	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
EAFF013472-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF022074-PA	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
EAFF014907-PA	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
EAFF014777-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EAFF004972-PA	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
EAFF006376-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF016477-PA	7	Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-8950505	"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
EAFF002443-PA	26	Reactome: R-HSA-400253;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907	"Circadian Clock";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"RORA activates gene expression";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors"
EAFF020771-PA	8	Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7524	"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway III (archaea)"
EAFF013906-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF010198-PA	5	MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-7082;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8	"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Oxidative phosphorylation"
EAFF014520-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EAFF009717-PA	5	Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
EAFF014382-PA	11	MetaCyc: PWY-5381;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-197264;Reactome: R-HSA-1538133;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1362300;Reactome: R-HSA-69205	"Pyridine nucleotide cycling (plants)";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Nicotinamide salvaging";"G0 and Early G1";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription"
EAFF005776-PA	5	Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
EAFF007659-PA	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
EAFF000787-PA	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
EAFF012077-PA	1	Reactome: R-HSA-8964038	"LDL clearance"
EAFF008174-PA	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids"
EAFF012574-PA	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
EAFF015765-PA	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF001991-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF015143-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
EAFF028218-PA	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF004751-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
EAFF003173-PA	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
EAFF012278-PA	8	Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411	"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere"
EAFF004765-PA	56	Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-8854050	"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
EAFF016498-PA	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
EAFF019213-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF008029-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF011521-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
EAFF018204-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EAFF007299-PA	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones"
EAFF028090-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EAFF005992-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF006279-PA	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
EAFF004873-PA	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
EAFF019030-PA	1	Reactome: R-HSA-525793	"Myogenesis"
EAFF025784-PA	4	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;Reactome: R-HSA-8964539;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Glutamate and glutamine metabolism";"Phosphatidylinositol signaling system"
EAFF019605-PA	33	Reactome: R-HSA-76042;Reactome: R-HSA-69231;Reactome: R-HSA-6782210;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-6781823;Reactome: R-HSA-69656;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin D associated events in G1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
EAFF007127-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF021276-PA	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
EAFF018641-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
EAFF014295-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
EAFF023754-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF001757-PA	57	Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-2871837	"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation"
EAFF009640-PA	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
EAFF017411-PA	6	Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
EAFF006118-PA	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
EAFF002177-PA	5	Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043	"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis"
EAFF028750-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
EAFF016863-PA	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
EAFF010080-PA	8	Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411	"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere"
EAFF017785-PA	12	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-674695	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events"
EAFF000696-PA	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
EAFF010408-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EAFF003066-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
EAFF009411-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF018689-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF007810-PA	7	MetaCyc: PWY-7854;MetaCyc: PWY-6969;MetaCyc: PWY-7118;MetaCyc: PWY-7295;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"L-arabinose degradation IV";"Pyruvate metabolism";"D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism"
EAFF010995-PA	8	Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
EAFF023346-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF006757-PA	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
EAFF000136-PA	8	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK"
EAFF004721-PA	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
EAFF021476-PA	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
EAFF024892-PA	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
EAFF003786-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF018684-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF018413-PA	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
EAFF005080-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF001926-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
EAFF018295-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
EAFF013753-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF012681-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF016056-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF013575-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF017855-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
EAFF024692-PA	20	KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"mTOR signalling";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Macroautophagy";"Thermogenesis";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"mTORC1-mediated signalling";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Human cytomegalovirus infection";"Amino acids regulate mTORC1";"Human papillomavirus infection"
EAFF007191-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF024435-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EAFF029150-PA	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
EAFF004027-PA	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
EAFF028220-PA	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
EAFF029567-PA	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
EAFF017412-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
EAFF020456-PA	1	Reactome: R-HSA-73614	"Pyrimidine salvage"
EAFF011741-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EAFF006280-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF019851-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF025361-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
EAFF005647-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF029148-PA	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
EAFF019036-PA	26	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-389960	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC"
EAFF001866-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
EAFF018304-PA	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
EAFF024284-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
EAFF003460-PA	4	Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Iron uptake and transport";"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF013835-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF022027-PA	3	Reactome: R-HSA-4085001;MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38	"Sialic acid metabolism";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis"
EAFF000017-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF007838-PA	27	Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408	"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ISG15 antiviral mechanism"
EAFF024495-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF012513-PA	27	Reactome: R-HSA-167152;Reactome: R-HSA-191859;Reactome: R-HSA-112382;Reactome: R-HSA-77595;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-77588;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-72187;Reactome: R-HSA-72086;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-159230;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-674695;Reactome: R-HSA-111367	"Formation of HIV elongation complex in the absence of HIV Tat";"snRNP Assembly";"Formation of RNA Pol II elongation complex";"Processing of Intronless Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"mRNA 3'-end processing";"mRNA Capping";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"Transport of the SLBP Dependant Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs"
EAFF029441-PA	7	KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-5129;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7836;MetaCyc: PWY-7841	"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis"
EAFF000810-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF018967-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF015140-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF000180-PA	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
EAFF001267-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF003911-PA	1	Reactome: R-HSA-6805567	"Keratinization"
EAFF024240-PA	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
EAFF018853-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF018096-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
EAFF010015-PA	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7619	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis"
EAFF027592-PA	4	MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8	"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
EAFF020609-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF016388-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF021269-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
EAFF003514-PA	14	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167242	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat"
EAFF018875-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF000195-PA	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
EAFF024496-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF005878-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF017844-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
EAFF020964-PA	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
EAFF027495-PA	1	Reactome: R-HSA-6805567	"Keratinization"
EAFF007009-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
EAFF018020-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
EAFF006925-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
EAFF001569-PA	1	Reactome: R-HSA-3295583	"TRP channels"
EAFF007059-PA	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
EAFF017786-PA	15	Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-114604;Reactome: R-HSA-416476	"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RET signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"GPVI-mediated activation cascade";"G alpha (q) signalling events"
EAFF004087-PA	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
EAFF024678-PA	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
EAFF009847-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF009994-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EAFF027463-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF013320-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF017424-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EAFF003509-PA	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
EAFF017552-PA	10	KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;MetaCyc: PWY-7385	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)"
EAFF027125-PA	14	MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
EAFF007129-PA	9	Reactome: R-HSA-1538133;Reactome: R-HSA-6804115;Reactome: R-HSA-1362300;Reactome: R-HSA-429947;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69656	"G0 and Early G1";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Deadenylation of mRNA";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry"
EAFF006475-PA	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
EAFF027287-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF007175-PA	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway"
EAFF019473-PA	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
EAFF018910-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF016662-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF022545-PA	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
EAFF016716-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF002142-PA	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
EAFF020934-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF027527-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF028755-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF005817-PA	5	Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-901042	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle"
EAFF018659-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF007736-PA	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
EAFF019219-PA	8	Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis"
EAFF008667-PA	3	Reactome: R-HSA-195399;Reactome: R-HSA-114608;Reactome: R-HSA-194313	"VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation";"VEGF ligand-receptor interactions"
EAFF019839-PA	11	Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-432040	"G alpha (z) signalling events";"PKA activation";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins"
EAFF022336-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF000838-PA	1	KEGG: 00500+2.4.1.15	"Starch and sucrose metabolism"
EAFF013223-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF021064-PA	2	Reactome: R-HSA-189483;Reactome: R-HSA-917937	"Heme degradation";"Iron uptake and transport"
EAFF005835-PA	6	MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
EAFF004052-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
EAFF013366-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
EAFF012469-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EAFF022354-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF010148-PA	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
EAFF006195-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
EAFF016502-PA	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF008070-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EAFF010922-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF021036-PA	24	Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-380320	"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes"
EAFF029381-PA	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF016541-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF022529-PA	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
EAFF018171-PA	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
EAFF003394-PA	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
EAFF023328-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF014754-PA	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
EAFF004086-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
EAFF014947-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EAFF002040-PA	26	Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-983189	"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Mitotic Prometaphase";"Kinesins"
EAFF002969-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF022421-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF013493-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EAFF025279-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF008025-PA	10	KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916	"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Hyaluronan uptake and degradation"
EAFF028395-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EAFF023564-PA	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF005264-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF002303-PA	5	Reactome: R-HSA-1483115;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801	"Hydrolysis of LPC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS"
EAFF021339-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF004494-PA	4	KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
EAFF006220-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF017376-PA	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
EAFF028866-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF006725-PA	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
EAFF013188-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF000116-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
EAFF025179-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
EAFF022516-PA	27	Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-165054	"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA"
EAFF009106-PA	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
EAFF011568-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF028076-PA	1	Reactome: R-HSA-5578775	"Ion homeostasis"
EAFF003178-PA	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
EAFF012391-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EAFF008803-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
EAFF025542-PA	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
EAFF015120-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
EAFF022686-PA	32	Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-8851708;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-674695	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Signaling by FGFR2 IIIa TM";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events"
EAFF017708-PA	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
EAFF007808-PA	7	MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-7295;MetaCyc: PWY-6969;MetaCyc: PWY-7854	"D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
EAFF020072-PA	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
EAFF027156-PA	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
EAFF013196-PA	8	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
EAFF023690-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EAFF021661-PA	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
EAFF017173-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF011659-PA	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-75953	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation"
EAFF012055-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF019821-PA	7	Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-5696395	"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of Incision Complex in GG-NER"
EAFF010587-PA	10	Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-611105	"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport"
EAFF007455-PA	26	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-389960	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC"
EAFF003193-PA	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
EAFF020596-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EAFF027252-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EAFF020617-PA	19	Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-3214858;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"RMTs methylate histone arginines";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"Selenocysteine synthesis";"Viral mRNA Translation"
EAFF005976-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF002672-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF014814-PA	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
EAFF021355-PA	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
EAFF019034-PA	26	Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-380320	"Mitotic Prometaphase";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes"
EAFF010817-PA	57	Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870	"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins"
EAFF028609-PA	2	KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004	"Pentose phosphate pathway";"Entner-Doudoroff pathway I"
EAFF019861-PA	5	Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
EAFF021986-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
EAFF023117-PA	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
EAFF016608-PA	8	Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2	"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Photosynthesis";"Amino acids regulate mTORC1";"ATP biosynthesis";"Insulin receptor recycling";"Oxidative phosphorylation"
EAFF026413-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF018014-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF006882-PA	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
EAFF011739-PA	7	MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7185;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Thiamine metabolism";"Purine metabolism"
EAFF012229-PA	17	KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-4381;Reactome: R-HSA-163765;MetaCyc: PWY-5744	"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"Biotin transport and metabolism";"Propanoate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation"
EAFF024323-PA	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
EAFF001776-PA	1	Reactome: R-HSA-425366	"Transport of bile salts and organic acids, metal ions and amine compounds"
EAFF012071-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF027981-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF010563-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF021765-PA	5	Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
EAFF022190-PA	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
EAFF022833-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EAFF025311-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF024677-PA	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
EAFF004069-PA	4	Reactome: R-HSA-499943;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695	"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism";"Neutrophil degranulation"
EAFF010754-PA	11	MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2	"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism"
EAFF021278-PA	17	Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210	"Dual Incision in GG-NER";"Polymerase switching";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
EAFF014392-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF017378-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF002426-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF012888-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF023991-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF021852-PA	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
EAFF019251-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF008401-PA	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
EAFF022066-PA	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
EAFF007809-PA	7	KEGG: 00620+2.3.3.9;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7854;MetaCyc: PWY-6969;MetaCyc: PWY-7295;MetaCyc: PWY-7118	"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV";"Chitin degradation to ethanol"
EAFF026128-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
EAFF010604-PA	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
EAFF009442-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EAFF025432-PA	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
EAFF029229-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF019744-PA	16	Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897	"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes"
EAFF010613-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
EAFF000008-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF008414-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF017958-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EAFF006572-PA	7	KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
EAFF002675-PA	12	MetaCyc: PWY-5872;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5873;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-6708;Reactome: R-HSA-2142789	"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis"
EAFF017679-PA	19	MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7574	"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II"
EAFF021376-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF012245-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF010524-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF000229-PA	9	Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
EAFF018370-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF005019-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
EAFF028865-PA	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
EAFF001478-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
EAFF003290-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
EAFF001759-PA	56	Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534	"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4"
EAFF005187-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF015513-PA	10	KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254	"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)"
EAFF004766-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF023530-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF004595-PA	17	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Meiotic synapsis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
EAFF026742-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EAFF015103-PA	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
EAFF002575-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF006938-PA	1	Reactome: R-HSA-8849175	"Threonine catabolism"
EAFF015089-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
EAFF018466-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
EAFF006377-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF018018-PA	24	Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-5663220	"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins"
EAFF009509-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF022803-PA	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
EAFF005615-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF010818-PA	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
EAFF002794-PA	27	Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214	"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins"
EAFF019168-PA	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
EAFF017400-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF017292-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF004171-PA	2	Reactome: R-HSA-139853;Reactome: R-HSA-418346	"Elevation of cytosolic Ca2+ levels";"Platelet homeostasis"
EAFF026687-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
EAFF018935-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF012562-PA	6	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol"
EAFF028222-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
EAFF013507-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EAFF009617-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
EAFF002442-PA	5	Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
EAFF007566-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EAFF018259-PA	5	Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4	"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
EAFF003626-PA	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
EAFF002165-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF000619-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EAFF025760-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
EAFF008841-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF004025-PA	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
EAFF025799-PA	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
EAFF019654-PA	9	Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-1855204	"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol"
EAFF009768-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
EAFF005791-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
EAFF006607-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF024538-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF016221-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
EAFF023517-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF017838-PA	7	MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
EAFF029735-PA	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
EAFF018468-PA	6	Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957	"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF024072-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF016435-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF012244-PA	11	MetaCyc: PWY-5381;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5	"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Purine metabolism"
EAFF008405-PA	3	Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
EAFF003873-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
EAFF020872-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF024672-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF005164-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
EAFF022939-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
EAFF010115-PA	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
EAFF004204-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF015809-PA	52	Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585	"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G"
EAFF000259-PA	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
EAFF004402-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
EAFF022575-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EAFF010153-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
EAFF015808-PA	52	Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751	"G2/M Checkpoints";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"UCH proteinases";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity"
EAFF010101-PA	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
EAFF023498-PA	11	Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-202733;Reactome: R-HSA-3560801	"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD"
EAFF004227-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
EAFF002951-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
EAFF007954-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF010812-PA	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
EAFF010320-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
EAFF001194-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF026980-PA	52	Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556	"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport"
EAFF003270-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EAFF013376-PA	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-156711;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Polo-like kinase mediated events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
EAFF021694-PA	29	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes"
EAFF028252-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF007614-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF013995-PA	19	Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888	"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"VLDL clearance";"LDL clearance";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance";"Chylomicron remodeling";"VLDL assembly";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Chylomicron assembly"
EAFF008364-PA	5	MetaCyc: PWY-2201;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20	"Folate transformations I";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
EAFF027040-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF014420-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EAFF026789-PA	11	Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418594	"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (i) signalling events"
EAFF007442-PA	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
EAFF018693-PA	11	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
EAFF012303-PA	3	MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96	"Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis"
EAFF005440-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
EAFF012898-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EAFF007958-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF003689-PA	5	Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922	"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I"
EAFF019249-PA	27	Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-191859	"ISG15 antiviral mechanism";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"snRNP Assembly"
EAFF009316-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EAFF007123-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF012193-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EAFF001632-PA	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
EAFF007576-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF019008-PA	3	Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation"
EAFF008099-PA	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
EAFF009371-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF014686-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF012806-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF008915-PA	4	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
EAFF018630-PA	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
EAFF006871-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF009167-PA	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
EAFF023232-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF027664-PA	12	MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation"
EAFF009370-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF019896-PA	7	Reactome: R-HSA-375276;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-140837	"Peptide ligand-binding receptors";"Post-translational protein phosphorylation";"Platelet degranulation";"G alpha (i) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation"
EAFF012231-PA	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
EAFF021337-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF027201-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF025355-PA	13	MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
EAFF023548-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF020798-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF012801-PA	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
EAFF007255-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
EAFF003396-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF009216-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF005042-PA	1	Reactome: R-HSA-420029	"Tight junction interactions"
EAFF005168-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
EAFF023520-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF016220-PA	2	Reactome: R-HSA-162791;Reactome: R-HSA-8955332	"Attachment of GPI anchor to uPAR";"Carboxyterminal post-translational modifications of tubulin"
EAFF004054-PA	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
EAFF006660-PA	8	MetaCyc: PWY-7979;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
EAFF017104-PA	7	MetaCyc: PWY-7625;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226	"Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PI"
EAFF010016-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF018421-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EAFF026103-PA	1	Reactome: R-HSA-8964572	"Lipid particle organization"
EAFF023183-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF002841-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF021817-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
EAFF012679-PA	56	Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895	"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis"
EAFF009627-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF021305-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF011669-PA	13	Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF006208-PA	2	Reactome: R-HSA-1462054;Reactome: R-HSA-1461973	"Alpha-defensins";"Defensins"
EAFF018393-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF008225-PA	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
EAFF015780-PA	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
EAFF026135-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EAFF013295-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF008949-PA	5	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413	"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression"
EAFF016168-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF002829-PA	4	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
EAFF021693-PA	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
EAFF013629-PA	24	Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-5663220	"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Gap junction assembly";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins"
EAFF019645-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
EAFF020608-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF020362-PA	8	MetaCyc: PWY-5723;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;MetaCyc: PWY-1861;Reactome: R-HSA-163754;Reactome: R-HSA-71336;Reactome: R-HSA-8950505	"Rubisco shunt";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
EAFF025717-PA	10	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-194840;Reactome: R-HSA-1839117;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Signaling by FGFR1 in disease";"Rho GTPase cycle";"Signaling by cytosolic FGFR1 fusion mutants";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
EAFF013977-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF027046-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
EAFF012211-PA	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)"
EAFF000930-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
EAFF017423-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
EAFF005369-PA	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
EAFF023514-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF019994-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF017948-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
EAFF017975-PA	4	Reactome: R-HSA-204005;Reactome: R-HSA-6798695;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Neutrophil degranulation";"Cargo concentration in the ER";"MHC class II antigen presentation"
EAFF011188-PA	5	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170	"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
EAFF015897-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
EAFF015394-PA	10	Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)"
EAFF010119-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF024006-PA	1	Reactome: R-HSA-373753	"Nephrin family interactions"
EAFF016393-PA	6	MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6731;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation III";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II"
EAFF001119-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF004982-PA	4	MetaCyc: PWY-6163;MetaCyc: PWY-5530;KEGG: 00400+2.7.1.71;KEGG: 00030+2.7.1.12	"Chorismate biosynthesis from 3-dehydroquinate";"Sorbitol biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Pentose phosphate pathway"
EAFF013909-PA	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
EAFF007060-PA	1	Reactome: R-HSA-1483148	"Synthesis of PG"
EAFF000169-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
EAFF008024-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF022572-PA	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
EAFF000972-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF013267-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EAFF010548-PA	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EAFF006008-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
EAFF003745-PA	8	KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis"
EAFF004040-PA	2	Reactome: R-HSA-139853;Reactome: R-HSA-418346	"Elevation of cytosolic Ca2+ levels";"Platelet homeostasis"
EAFF017993-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF014880-PA	1	Reactome: R-HSA-140837	"Intrinsic Pathway of Fibrin Clot Formation"
EAFF017323-PA	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
EAFF029168-PA	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
EAFF010326-PA	13	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF019121-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF026411-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF024075-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF004112-PA	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
EAFF024882-PA	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
EAFF025233-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF005432-PA	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
EAFF021900-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
EAFF001229-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
EAFF001992-PA	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
EAFF015665-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EAFF019576-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF004729-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
EAFF011765-PA	26	Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-5663220	"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins"
EAFF011297-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF004487-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF001766-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF024498-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
EAFF000161-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
EAFF021499-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF009849-PA	14	Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes"
EAFF007670-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF026045-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EAFF001758-PA	56	Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-202424	"G2/M Checkpoints";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Downstream TCR signaling"
EAFF027182-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
EAFF002767-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
EAFF023493-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF029583-PA	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
EAFF026740-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EAFF008063-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF021081-PA	13	Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF019596-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF011855-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EAFF020240-PA	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
EAFF016905-PA	5	MetaCyc: PWY-7622;KEGG: 00520+5.4.99.9;MetaCyc: PWY-6397;KEGG: 00052+5.4.99.9;MetaCyc: PWY-7328	"UDP-alpha-D-galactofuranose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis"
EAFF026535-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF021774-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
EAFF005202-PA	3	MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis"
EAFF011592-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF008399-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF028846-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EAFF023378-PA	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
EAFF001908-PA	5	Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209560	"Interleukin-1 signaling";"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival"
EAFF002981-PA	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
EAFF001542-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF006596-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EAFF002584-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF002843-PA	7	Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972	"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
EAFF028572-PA	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
EAFF012665-PA	13	MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism"
EAFF027394-PA	5	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-201722	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex"
EAFF020184-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
EAFF001613-PA	6	Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261	"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I"
EAFF029163-PA	5	Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785	"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome"
EAFF024451-PA	7	Reactome: R-HSA-6811434;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"COPI-mediated anterograde transport"
EAFF014951-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF013266-PA	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-1799339;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"SRP-dependent cotranslational protein targeting to membrane";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
EAFF028397-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EAFF011328-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF017419-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF018919-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF022392-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF008232-PA	1	Reactome: R-HSA-8935690	"Digestion"
EAFF028861-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF021578-PA	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
EAFF007352-PA	11	Reactome: R-HSA-5689880;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695	"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events"
EAFF024488-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
EAFF016354-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
EAFF009464-PA	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
EAFF008173-PA	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
EAFF016283-PA	4	Reactome: R-HSA-189483;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;MetaCyc: PWY-5874	"Heme degradation";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation I"
EAFF011139-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EAFF001244-PA	3	KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism"
EAFF017285-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF013842-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
EAFF027460-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF026108-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF008737-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF016508-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF007354-PA	11	Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665	"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells"
EAFF004241-PA	5	MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism"
EAFF005416-PA	19	Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-8856825	"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Chylomicron assembly";"Chylomicron remodeling";"VLDL assembly";"Chylomicron clearance";"Post-translational protein phosphorylation";"VLDL clearance";"Regulation of TLR by endogenous ligand";"LDL clearance";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"LDL remodeling";"Cell surface interactions at the vascular wall";"Cargo recognition for clathrin-mediated endocytosis"
EAFF027761-PA	8	KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1	"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism"
EAFF013406-PA	1	Reactome: R-HSA-140834	"Extrinsic Pathway of Fibrin Clot Formation"
EAFF020406-PA	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
EAFF002968-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EAFF017963-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF018069-PA	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
EAFF001534-PA	25	Reactome: R-HSA-8941332;Reactome: R-HSA-8941858;Reactome: R-HSA-8941326;Reactome: R-HSA-9616222;Reactome: R-HSA-8939247;Reactome: R-HSA-8878166;Reactome: R-HSA-8936459;Reactome: R-HSA-8951911;Reactome: R-HSA-8949275;Reactome: R-HSA-8939256;Reactome: R-HSA-8935964;Reactome: R-HSA-8940973;Reactome: R-HSA-8931987;Reactome: R-HSA-8939246;Reactome: R-HSA-8939245;Reactome: R-HSA-8877330;Reactome: R-HSA-8939236;Reactome: R-HSA-8941333;Reactome: R-HSA-8951936;Reactome: R-HSA-8934593;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8941284;Reactome: R-HSA-9018519;Reactome: R-HSA-8939902	"RUNX2 regulates genes involved in cell migration";"Regulation of RUNX3 expression and activity";"RUNX2 regulates bone development";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Transcriptional regulation by RUNX2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF";"Regulation of RUNX1 Expression and Activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates chondrocyte maturation";"Estrogen-dependent gene expression";"Regulation of RUNX2 expression and activity"
EAFF028935-PA	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
EAFF010681-PA	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
EAFF023211-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EAFF015607-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF001420-PA	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
EAFF019311-PA	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
EAFF015021-PA	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
EAFF025056-PA	15	MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886	"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)"
EAFF014575-PA	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
EAFF002935-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF005017-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF020137-PA	16	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF012390-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EAFF001182-PA	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
EAFF029261-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
EAFF024280-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
EAFF017148-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF004764-PA	56	Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174178	"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
EAFF005920-PA	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
EAFF010139-PA	5	MetaCyc: PWY-7863;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-5523	"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)"
EAFF022767-PA	2	MetaCyc: PWY-6717;MetaCyc: PWY-6784	"(1,4)-beta-D-xylan degradation";"Cellulose and hemicellulose degradation (cellulolosome)"
EAFF022835-PA	9	Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400206	"Circadian Clock";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha"
EAFF022378-PA	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA"
EAFF020820-PA	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
EAFF001502-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF017984-PA	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
EAFF017720-PA	7	Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6798695	"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"Neutrophil degranulation"
EAFF022366-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF006364-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF015387-PA	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
EAFF004136-PA	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Selenocompound metabolism"
EAFF000023-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF023098-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF018624-PA	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EAFF020905-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF026548-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
EAFF003825-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF002182-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF019583-PA	5	Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling"
EAFF025489-PA	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
EAFF029395-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
EAFF001095-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF024861-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
EAFF022542-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
EAFF029673-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
EAFF006149-PA	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)"
EAFF002780-PA	26	Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276	"Aggrephagy";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint"
EAFF010132-PA	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
EAFF003764-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EAFF001479-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF023970-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF005095-PA	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
EAFF012508-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF021832-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EAFF026673-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF026255-PA	6	KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5484	"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)"
EAFF014178-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
EAFF021306-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF013092-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
EAFF028084-PA	1	Reactome: R-HSA-5578775	"Ion homeostasis"
EAFF010332-PA	4	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
EAFF007701-PA	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
EAFF017526-PA	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
EAFF027755-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EAFF021853-PA	4	Reactome: R-HSA-3359474;Reactome: R-HSA-3359473;Reactome: R-HSA-196741;Reactome: R-HSA-947581	"Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Molybdenum cofactor biosynthesis"
EAFF021760-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EAFF022212-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF018743-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EAFF005122-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
EAFF010823-PA	24	Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Separation of Sister Chromatids";"Kinesins";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin"
EAFF019281-PA	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
EAFF008349-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF019184-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF001859-PA	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
EAFF011302-PA	57	Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5358346	"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Neutrophil degranulation";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI1 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis"
EAFF022469-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF010113-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF017596-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
EAFF001242-PA	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
EAFF021351-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF002605-PA	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Synthesis of PC";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis"
EAFF024457-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EAFF010135-PA	16	Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
EAFF003949-PA	6	KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1	"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms"
EAFF014546-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF019680-PA	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
EAFF002963-PA	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
EAFF027101-PA	3	Reactome: R-HSA-8957275;Reactome: R-HSA-5362798;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
EAFF020792-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
EAFF015292-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
EAFF012203-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF014015-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
EAFF003795-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF004135-PA	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
EAFF011994-PA	4	MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6	"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation";"Cysteine and methionine metabolism"
EAFF017854-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF020216-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
EAFF025718-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF009410-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF029779-PA	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
EAFF002464-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF007407-PA	12	MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-7385;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Methane metabolism";"Fructose and mannose metabolism";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis"
EAFF000443-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
EAFF004997-PA	9	Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237	"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT2 causes exostoses 2"
EAFF014201-PA	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
EAFF005624-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
EAFF025183-PA	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
EAFF016859-PA	13	MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7220	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II"
EAFF000046-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF017045-PA	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
EAFF018784-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EAFF023465-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EAFF014402-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
EAFF014885-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF007705-PA	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
EAFF010652-PA	12	Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
EAFF010833-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF017372-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF019214-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF006644-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
EAFF004616-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF028536-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF024497-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
EAFF006765-PA	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
EAFF008733-PA	3	Reactome: R-HSA-983168;Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"Antigen processing: Ubiquitination & Proteasome degradation";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
EAFF001865-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
EAFF023762-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF022094-PA	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
EAFF005425-PA	13	KEGG: 00230+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7821;MetaCyc: PWY-7184;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.66	"Purine metabolism";"Purine catabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism"
EAFF003316-PA	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
EAFF017276-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF015230-PA	5	Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
EAFF004246-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF009993-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
EAFF004776-PA	10	MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-1722	"L-histidine degradation III";"One carbon pool by folate";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate"
EAFF002950-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EAFF000713-PA	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF013218-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF021981-PA	4	Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-446203	"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Asparagine N-linked glycosylation"
EAFF009688-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EAFF003001-PA	3	KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
EAFF016549-PA	22	Reactome: R-HSA-432142;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751	"Platelet sensitization by LDL";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"RAF activation";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated"
EAFF028618-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EAFF014741-PA	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
EAFF011672-PA	40	Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-75955	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation"
EAFF014193-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
EAFF002936-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EAFF025959-PA	29	Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167160	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
EAFF020829-PA	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
EAFF007198-PA	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
EAFF015985-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
EAFF001256-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF016579-PA	7	Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
EAFF026818-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF017538-PA	4	KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221	"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis"
EAFF007088-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF009138-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF014042-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010125-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
EAFF010680-PA	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
EAFF028416-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
EAFF017184-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
EAFF007869-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
EAFF006699-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF006419-PA	3	Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669	"Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
EAFF000234-PA	11	MetaCyc: PWY-5695;MetaCyc: PWY-6607;MetaCyc: PWY-5381;MetaCyc: PWY-6608;MetaCyc: PWY-7821;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5	"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Purine metabolism"
EAFF020711-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
EAFF015941-PA	1	KEGG: 00290+4.2.1.33	"Valine, leucine and isoleucine biosynthesis"
EAFF008224-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
EAFF007158-PA	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
EAFF021411-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EAFF008893-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF018563-PA	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
EAFF000885-PA	18	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7187	"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
EAFF014252-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF007064-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
EAFF001636-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF008042-PA	6	Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
EAFF003529-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010066-PA	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
EAFF013598-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
EAFF006803-PA	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
EAFF026430-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF000446-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF013811-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF021973-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF013455-PA	7	Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539	"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism"
EAFF005015-PA	8	MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5744	"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation"
EAFF013122-PA	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
EAFF025510-PA	3	Reactome: R-HSA-8957275;Reactome: R-HSA-5362798;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
EAFF027651-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF005311-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF012323-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
EAFF021892-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EAFF024296-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF000677-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF019315-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis"
EAFF026080-PA	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
EAFF008584-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF025859-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EAFF003536-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF024091-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
EAFF025958-PA	29	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-112382	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex"
EAFF002024-PA	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
EAFF021770-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF003682-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EAFF012499-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
EAFF008128-PA	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
EAFF017519-PA	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
EAFF016297-PA	6	MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
EAFF001080-PA	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
EAFF016007-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
EAFF009696-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EAFF004546-PA	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
EAFF004741-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF010671-PA	4	KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22	"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism"
EAFF017706-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF003019-PA	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
EAFF026785-PA	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"PKA activation"
EAFF006745-PA	5	MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism"
EAFF018763-PA	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
EAFF017850-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF007640-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EAFF021054-PA	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
EAFF006205-PA	1	Reactome: R-HSA-140837	"Intrinsic Pathway of Fibrin Clot Formation"
EAFF018969-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF029317-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
EAFF010009-PA	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
EAFF003100-PA	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
EAFF022135-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF003251-PA	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
EAFF001327-PA	25	Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-380270;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Mitotic Prometaphase";"Gap junction assembly";"Recruitment of mitotic centrosome proteins and complexes";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
EAFF028688-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF025739-PA	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
EAFF022396-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF002828-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF021140-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
EAFF000768-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
EAFF021079-PA	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF005356-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF024704-PA	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
EAFF019878-PA	4	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis"
EAFF014820-PA	7	KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
EAFF014005-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EAFF028083-PA	1	Reactome: R-HSA-5578775	"Ion homeostasis"
EAFF013883-PA	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
EAFF015231-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF018687-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF011219-PA	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
EAFF008945-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
EAFF006094-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
EAFF001560-PA	24	Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-437239	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HCMV Early Events";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Recycling pathway of L1"
EAFF006024-PA	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
EAFF013534-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF016674-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF020533-PA	3	Reactome: R-HSA-3299685;Reactome: R-HSA-71288;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Creatine metabolism";"Glutathione metabolism"
EAFF018698-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF020140-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EAFF004212-PA	4	KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
EAFF025705-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF026211-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF000848-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF020879-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF003010-PA	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
EAFF019038-PA	26	Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-6811434	"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"HCMV Early Events";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF008799-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EAFF004215-PA	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
EAFF017402-PA	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF029236-PA	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
EAFF003654-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
EAFF002720-PA	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
EAFF025181-PA	4	Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
EAFF027773-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF001276-PA	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
EAFF004300-PA	16	Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-190873;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-196025	"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Gap junction degradation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"LDL clearance";"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Formation of annular gap junctions"
EAFF015621-PA	8	Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
EAFF006594-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
EAFF007094-PA	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection"
EAFF007753-PA	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
EAFF004213-PA	5	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription"
EAFF013296-PA	13	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5392	"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II"
EAFF000359-PA	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
EAFF014106-PA	5	Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
EAFF025555-PA	1	MetaCyc: PWY-7379	"Mrna capping II"
EAFF024841-PA	5	Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001	"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism"
EAFF013271-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010150-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF026922-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
EAFF009141-PA	5	MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902	"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis"
EAFF016992-PA	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
EAFF004053-PA	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
EAFF008855-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
EAFF017913-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EAFF010240-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF002106-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF016279-PA	5	Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-9020702	"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"Interleukin-1 signaling"
EAFF001166-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF026692-PA	4	KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268	"Glutathione metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
EAFF022140-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF014522-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EAFF014521-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EAFF017831-PA	24	Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2132295	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"MHC class II antigen presentation"
EAFF002153-PA	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
EAFF004049-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF018992-PA	12	Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4"
EAFF013372-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF016972-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF026004-PA	27	Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly"
EAFF020141-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EAFF000111-PA	10	MetaCyc: PWY-6932;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4	"Selenate reduction";"Transport and synthesis of PAPS";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Selenocompound metabolism"
EAFF019485-PA	11	KEGG: 00250+6.3.5.5;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7400;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5154	"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
EAFF011307-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF023804-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF023228-PA	12	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Ether lipid metabolism"
EAFF021275-PA	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
EAFF029533-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF005233-PA	1	Reactome: R-HSA-446193	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
EAFF022026-PA	11	Reactome: R-HSA-202733;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170	"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions"
EAFF022829-PA	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
EAFF000494-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF001308-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF002639-PA	6	KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Galactose metabolism";"Sphingolipid metabolism"
EAFF010745-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
EAFF003859-PA	6	Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795	"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling"
EAFF027850-PA	5	Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516	"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin"
EAFF006276-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF006022-PA	6	Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
EAFF019811-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF028904-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
EAFF011100-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF023521-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010114-PA	6	Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
EAFF026204-PA	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
EAFF006057-PA	10	MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-5826	"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis"
EAFF015239-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EAFF006900-PA	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
EAFF019758-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF015049-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
EAFF020937-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF007706-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
EAFF014886-PA	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
EAFF014232-PA	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
EAFF009053-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF017515-PA	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
EAFF021477-PA	9	Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape"
EAFF000790-PA	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
EAFF022571-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF026258-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF018805-PA	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172	"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions"
EAFF026937-PA	4	MetaCyc: PWY-7805;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III"
EAFF019169-PA	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
EAFF003174-PA	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
EAFF003918-PA	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
EAFF023288-PA	8	Reactome: R-HSA-71336;KEGG: 00710+5.3.1.6;Reactome: R-HSA-5659996;KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
EAFF009120-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
EAFF027844-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF011152-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
EAFF003320-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF011081-PA	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
EAFF028038-PA	18	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7221;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-6545	"Purine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
EAFF006104-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF024991-PA	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
EAFF026287-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF007719-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EAFF028868-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
EAFF014467-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF003052-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF022739-PA	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
EAFF027059-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EAFF006340-PA	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
EAFF018692-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF022147-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF027538-PA	5	Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209560	"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival"
EAFF017642-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF020543-PA	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
EAFF008521-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
EAFF003803-PA	6	Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion"
EAFF012698-PA	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
EAFF011236-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF001410-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF025178-PA	20	Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-110314	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex"
EAFF026843-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
EAFF000712-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF026256-PA	2	Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Glycolysis";"Gluconeogenesis"
EAFF026421-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF007025-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF017090-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF020526-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF027715-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
EAFF018924-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
EAFF008802-PA	1	Reactome: R-HSA-9640463	"Wax biosynthesis"
EAFF007519-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF018359-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF001183-PA	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
EAFF009212-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF007627-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EAFF005669-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
EAFF011082-PA	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
EAFF023345-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF005287-PA	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
EAFF019269-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF012747-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
EAFF021582-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF000271-PA	2	Reactome: R-HSA-917937;Reactome: R-HSA-189483	"Iron uptake and transport";"Heme degradation"
EAFF006426-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF004658-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EAFF024864-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF004655-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EAFF000770-PA	7	MetaCyc: PWY-4984;MetaCyc: PWY-31;MetaCyc: PWY-46;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;KEGG: 00220+3.5.3.1;MetaCyc: PWY-6922	"Urea cycle";"Canavanine degradation";"Putrescine biosynthesis III";"Urea cycle";"Arginine and proline metabolism";"Arginine biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
EAFF000080-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF027039-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF023321-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF008811-PA	11	KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.9	"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Purine metabolism"
EAFF007709-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF005116-PA	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
EAFF013091-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
EAFF017248-PA	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
EAFF011067-PA	3	Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722	"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
EAFF023150-PA	22	Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337	"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding"
EAFF018355-PA	1	Reactome: R-HSA-264876	"Insulin processing"
EAFF014873-PA	52	Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-180534	"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Vpu mediated degradation of CD4"
EAFF005148-PA	13	MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6969	"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
EAFF027364-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF004484-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
EAFF022693-PA	2	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
EAFF011493-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EAFF000820-PA	3	Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
EAFF001404-PA	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
EAFF005572-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
EAFF025506-PA	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell"
EAFF028559-PA	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
EAFF020877-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF005345-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
EAFF002376-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF012648-PA	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
EAFF013006-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF018932-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF009963-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
EAFF022075-PA	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
EAFF029716-PA	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
EAFF025052-PA	7	Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
EAFF017482-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
EAFF020139-PA	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
EAFF010698-PA	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
EAFF023839-PA	52	Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-73776;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-6781823;Reactome: R-HSA-5601884;Reactome: R-HSA-72165;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-6781827	"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of TC-NER Pre-Incision Complex";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Minor Pathway";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
EAFF028853-PA	15	Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238	"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation"
EAFF019772-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF014794-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
EAFF000188-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
EAFF023016-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
EAFF008054-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
EAFF021037-PA	24	Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-380320	"Kinesins";"Mitotic Prometaphase";"MHC class II antigen presentation";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
EAFF014213-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EAFF016197-PA	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EAFF014847-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF009029-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF020517-PA	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
EAFF007696-PA	29	Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6782210	"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER"
EAFF012313-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF011532-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
EAFF000502-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
EAFF004656-PA	10	Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-445144	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Synthesis of PC";"Signal transduction by L1"
EAFF028373-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EAFF016075-PA	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
EAFF015620-PA	3	KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2	"Photosynthesis";"ATP biosynthesis";"Oxidative phosphorylation"
EAFF000144-PA	17	MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
EAFF007687-PA	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
EAFF025194-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF001867-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
EAFF003939-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF014359-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EAFF003748-PA	26	Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-389977	"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"MHC class II antigen presentation";"Mitotic Prometaphase";"Kinesins";"Cilium Assembly";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway"
EAFF000035-PA	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
EAFF017587-PA	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
EAFF017240-PA	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
EAFF004710-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF020486-PA	13	KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822	"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
EAFF000272-PA	10	MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2	"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism"
EAFF011237-PA	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
EAFF011611-PA	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
EAFF025353-PA	5	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones"
EAFF013781-PA	5	Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657	"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes"
EAFF003008-PA	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
EAFF005459-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
EAFF008556-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EAFF005623-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
EAFF001177-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
EAFF005316-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF021056-PA	1	Reactome: R-HSA-8849175	"Threonine catabolism"
EAFF000807-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF011209-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF004106-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF001985-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF023569-PA	12	MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism"
EAFF001634-PA	5	Reactome: R-HSA-5619049;Reactome: R-HSA-917937;Reactome: R-HSA-425410;Reactome: R-HSA-5655799;Reactome: R-HSA-5619060	"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages)";"Iron uptake and transport";"Metal ion SLC transporters";"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)";"Defective CP causes aceruloplasminemia (ACERULOP)"
EAFF003318-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EAFF007597-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF021592-PA	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
EAFF008894-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF005938-PA	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
EAFF004290-PA	9	MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590	"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione conjugation"
EAFF017724-PA	1	KEGG: 00500+2.4.1.15	"Starch and sucrose metabolism"
EAFF015162-PA	11	Reactome: R-HSA-5358565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
EAFF000541-PA	4	MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;MetaCyc: PWY-7791	"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III"
EAFF010965-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EAFF012982-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
EAFF006351-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF019860-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF004340-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
EAFF005171-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF000594-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF021820-PA	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
EAFF008839-PA	16	Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EAFF001785-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF000112-PA	12	KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932	"Monobactam biosynthesis";"Sulfur metabolism";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Purine metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Selenate reduction"
EAFF006113-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
EAFF007420-PA	7	Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1362300	"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
EAFF002233-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF005348-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF018794-PA	4	Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211	"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes"
EAFF018852-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF016576-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
EAFF002798-PA	27	Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531	"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus"
EAFF001754-PA	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
EAFF005657-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF025801-PA	26	Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-380320	"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes"
EAFF025177-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EAFF008597-PA	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EAFF010196-PA	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA"
EAFF004182-PA	15	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
EAFF014110-PA	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
EAFF002467-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
EAFF002404-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EAFF006314-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
EAFF022528-PA	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
EAFF015528-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
EAFF017170-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EAFF029526-PA	56	Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174154	"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin"
EAFF028181-PA	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
EAFF001226-PA	30	Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-2564830;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Cytosolic iron-sulfur cluster assembly";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
EAFF025938-PA	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210	"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
EAFF022468-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF003957-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EAFF018073-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EAFF029185-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
EAFF015788-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF005668-PA	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EAFF001198-PA	6	Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-110362	"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair"
EAFF003746-PA	8	KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1	"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis"
EAFF001734-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
EAFF023409-PA	5	Reactome: R-HSA-73614;Reactome: R-HSA-69205;KEGG: 00240+2.7.1.21;KEGG: 00983+2.7.1.21;MetaCyc: PWY-7199	"Pyrimidine salvage";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage"
EAFF021098-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF012425-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF004784-PA	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
EAFF020969-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF004265-PA	11	Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-112382	"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex"
EAFF003422-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF006450-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
EAFF003703-PA	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
EAFF011017-PA	6	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs"
EAFF008400-PA	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
EAFF013606-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF020501-PA	15	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates"
EAFF002687-PA	12	KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118	"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol"
EAFF007045-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF021527-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF019550-PA	5	KEGG: 00550+6.3.2.4;MetaCyc: PWY-6386;MetaCyc: PWY-7953;KEGG: 00473+6.3.2.4;MetaCyc: PWY-6387	"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"D-Alanine metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)"
EAFF012613-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
EAFF000352-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
EAFF002965-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF000437-PA	28	Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-389977;Reactome: R-HSA-72163;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-6807505;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-983189	"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway";"mRNA Splicing - Major Pathway";"Recycling pathway of L1";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"RNA polymerase II transcribes snRNA genes";"Cilium Assembly";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Gap junction assembly";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins"
EAFF003920-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation"
EAFF004115-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EAFF017591-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF005883-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EAFF001332-PA	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
EAFF004695-PA	1	Reactome: R-HSA-5676934	"Protein repair"
EAFF014813-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
EAFF004170-PA	2	Reactome: R-HSA-418346;Reactome: R-HSA-139853	"Platelet homeostasis";"Elevation of cytosolic Ca2+ levels"
EAFF011666-PA	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
EAFF004778-PA	7	KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-2201	"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate transformations II (plants)";"Folate transformations I"
EAFF012541-PA	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
EAFF018080-PA	6	KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
EAFF016862-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF010820-PA	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
EAFF009721-PA	10	MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-6613;Reactome: R-HSA-196757	"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Folate transformations II (plants)";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines"
EAFF004525-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF014412-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF005426-PA	6	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs"
EAFF003063-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF011318-PA	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
EAFF024046-PA	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737	"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation II";"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V"
EAFF029437-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
EAFF028566-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF002837-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF013222-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
EAFF009178-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF003395-PA	9	Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
EAFF000818-PA	20	MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7337;MetaCyc: PWY-6837	"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
EAFF020423-PA	1	Reactome: R-HSA-427589	"Type II Na+/Pi cotransporters"
EAFF018095-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
EAFF004591-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF000307-PA	4	Reactome: R-HSA-390247;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9	"Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoate metabolism"
EAFF008036-PA	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
EAFF007700-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF008345-PA	26	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-389960	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Gap junction assembly";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC"
EAFF022553-PA	1	KEGG: 00290+4.2.1.33	"Valine, leucine and isoleucine biosynthesis"
EAFF003082-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF022570-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF003968-PA	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
EAFF020439-PA	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
EAFF002107-PA	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
EAFF010304-PA	2	Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
EAFF020388-PA	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
EAFF022389-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
EAFF018860-PA	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
EAFF020152-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF024045-PA	7	MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25	"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism"
EAFF004651-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
EAFF001735-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF014540-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF010952-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
EAFF016975-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF004839-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF022383-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF013696-PA	7	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
EAFF024491-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF014358-PA	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
EAFF017480-PA	10	Reactome: R-HSA-380972;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-189451	"Energy dependent regulation of mTOR by LKB1-AMPK";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Heme biosynthesis"
EAFF021248-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
EAFF000344-PA	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
EAFF005618-PA	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EAFF004312-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF024813-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF028748-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
EAFF023464-PA	5	Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-9013973	"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7"
EAFF017214-PA	7	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;Reactome: R-HSA-2151201	"Oxidative phosphorylation";"Mitochondrial protein import";"Photosynthesis";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis"
EAFF022318-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF008140-PA	6	KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism"
EAFF023958-PA	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
EAFF007098-PA	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
EAFF028933-PA	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
EAFF026978-PA	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
EAFF014074-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
EAFF014055-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
EAFF014121-PA	5	MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification"
EAFF018122-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF008033-PA	5	Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756	"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation"
EAFF000984-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF023240-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
EAFF021330-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
EAFF007408-PA	12	MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;Reactome: R-HSA-70171	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis"
EAFF029038-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF009585-PA	11	KEGG: 00450+2.1.1.13;MetaCyc: PWY-3841;Reactome: R-HSA-3359467;Reactome: R-HSA-3359469;KEGG: 00270+2.1.1.13;Reactome: R-HSA-196741;MetaCyc: PWY-7977;Reactome: R-HSA-156581;Reactome: R-HSA-1614635;MetaCyc: PWY-2201;KEGG: 00670+2.1.1.13	"Selenocompound metabolism";"Folate transformations II (plants)";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Cysteine and methionine metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"L-methionine biosynthesis IV (archaea)";"Methylation";"Sulfur amino acid metabolism";"Folate transformations I";"One carbon pool by folate"
EAFF011510-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF024893-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
EAFF016118-PA	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
EAFF019502-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF025927-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF003097-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF018815-PA	7	Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends"
EAFF009349-PA	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
EAFF006651-PA	1	Reactome: R-HSA-71262	"Carnitine synthesis"
EAFF013471-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF028281-PA	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
EAFF027091-PA	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
EAFF005993-PA	8	Reactome: R-HSA-6787639;MetaCyc: PWY-5740;MetaCyc: PWY-66;MetaCyc: PWY-5738;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5739	"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-D-perosamine biosynthesis"
EAFF011208-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF022576-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation"
EAFF024282-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
EAFF000866-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF029666-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF002520-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
EAFF023066-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
EAFF011969-PA	8	Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
EAFF029382-PA	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex"
EAFF001132-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
EAFF008827-PA	56	Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-211733	"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
EAFF014247-PA	4	Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
EAFF028580-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
EAFF021655-PA	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
EAFF012651-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF018193-PA	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
EAFF015731-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
EAFF014946-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
EAFF002466-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
EAFF026069-PA	19	MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7224;Reactome: R-HSA-156842;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7197;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Eukaryotic Translation Elongation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism"
EAFF005802-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF012200-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF010502-PA	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
EAFF023565-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
EAFF028691-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
EAFF018352-PA	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
EAFF026533-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF021200-PA	7	Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381042	"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression"
EAFF024891-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF001575-PA	3	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EAFF006602-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF023108-PA	7	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
EAFF001877-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
EAFF022160-PA	57	Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174154	"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin"
EAFF023837-PA	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
EAFF006219-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EAFF002854-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF019178-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
EAFF019504-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF011541-PA	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF021802-PA	7	KEGG: 00051+3.1.3.11;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;MetaCyc: PWY-5484	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)"
EAFF016258-PA	27	Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214	"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins"
EAFF023546-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF004503-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF002757-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF005392-PA	27	Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159230	"Transcriptional regulation by small RNAs";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA"
EAFF019120-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF024320-PA	7	MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445	"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation"
EAFF001077-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF027722-PA	17	Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-113418;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Th1 and Th2 cell differentiation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
EAFF027750-PA	56	Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome"
EAFF025212-PA	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
EAFF022278-PA	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
EAFF017849-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF015737-PA	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
EAFF002323-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
EAFF010019-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF021218-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF001578-PA	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection"
EAFF008116-PA	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
EAFF023630-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF000476-PA	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
EAFF007194-PA	3	KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
EAFF010821-PA	24	Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-380320	"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes"
EAFF016997-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EAFF015754-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF024146-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
EAFF022352-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF024076-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF006114-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF015375-PA	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
EAFF014329-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF001660-PA	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
EAFF004225-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF027611-PA	10	KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-7559	"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway"
EAFF026983-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF020696-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF022827-PA	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
EAFF015806-PA	52	Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870	"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"UCH proteinases";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins"
EAFF013456-PA	7	KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921	"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
EAFF008626-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EAFF008558-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
EAFF018467-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EAFF025323-PA	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
EAFF015275-PA	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
EAFF017873-PA	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
EAFF002742-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EAFF018338-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF019926-PA	5	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
EAFF021404-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
EAFF012958-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF022854-PA	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
EAFF025246-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF001013-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF005046-PA	8	MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7733;MetaCyc: PWY-7734;MetaCyc: PWY-7717;KEGG: 00380+3.5.1.9;MetaCyc: PWY-5651	"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
EAFF017481-PA	7	Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159	"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling"
EAFF002114-PA	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034	"Hedgehog 'on' state";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np"
EAFF006825-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF006143-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF012961-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
EAFF024870-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EAFF007038-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF002174-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF023428-PA	3	Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413	"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression"
EAFF016109-PA	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
EAFF022612-PA	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
EAFF009312-PA	6	Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex"
EAFF015235-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
EAFF018289-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF028936-PA	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EAFF002134-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
EAFF013650-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
EAFF023020-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF015244-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
EAFF028893-PA	1	Reactome: R-HSA-196757	"Metabolism of folate and pterines"
EAFF010325-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
EAFF025747-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF001901-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF018453-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF020741-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
EAFF021424-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
EAFF013824-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
EAFF010133-PA	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
EAFF020107-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF005474-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
EAFF021811-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
EAFF026675-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF014123-PA	2	MetaCyc: PWY-6466;KEGG: 00750+4.3.3.6	"Pyridoxal 5'-phosphate biosynthesis II";"Vitamin B6 metabolism"
EAFF005310-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF001190-PA	5	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
EAFF013807-PA	56	Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-8939902	"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity"
EAFF008664-PA	4	Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20	"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism"
EAFF016683-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EAFF017284-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF024071-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF022589-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
EAFF023810-PA	18	Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
EAFF014376-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF015136-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EAFF015210-PA	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
EAFF012714-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF017955-PA	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
EAFF005473-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
EAFF009423-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EAFF028697-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF014952-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF016317-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
EAFF025321-PA	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
EAFF001187-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EAFF005604-PA	3	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF029237-PA	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
EAFF018879-PA	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
EAFF019992-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
EAFF024494-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
EAFF008297-PA	16	Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-69017	"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6"
EAFF000697-PA	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
EAFF000275-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination"
EAFF027888-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF014401-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
EAFF002967-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF023330-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF011599-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
EAFF005977-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF009671-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF015110-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
EAFF005829-PA	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
EAFF011190-PA	5	Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604	"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling"
EAFF000031-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
EAFF003849-PA	4	Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
EAFF008135-PA	3	KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
EAFF019628-PA	6	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
EAFF001900-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF006653-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF013459-PA	9	Reactome: R-HSA-1368108;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly";"PPARA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
EAFF025060-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
EAFF005516-PA	7	MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I"
EAFF025912-PA	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
EAFF009021-PA	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
EAFF009850-PA	14	Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis"
EAFF014443-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF005251-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF021486-PA	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
EAFF016991-PA	11	Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport"
EAFF006339-PA	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
EAFF022924-PA	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
EAFF010108-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
EAFF011314-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF005455-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
EAFF000025-PA	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
EAFF025163-PA	10	Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-432720	"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Inhibition of membrane repair";"Negative regulation of MET activity";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis"
EAFF007713-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF027912-PA	1	Reactome: R-HSA-2408557	"Selenocysteine synthesis"
EAFF002504-PA	6	Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211	"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes"
EAFF021763-PA	5	Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695	"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neutrophil degranulation"
EAFF007616-PA	5	Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37	"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism"
EAFF011057-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF004311-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF002977-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
EAFF010674-PA	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
EAFF014446-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF013280-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF027129-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
EAFF009957-PA	5	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC"
EAFF002674-PA	4	Reactome: R-HSA-3359475;Reactome: R-HSA-71032;Reactome: R-HSA-3359478;Reactome: R-HSA-196741	"Defective MMAA causes methylmalonic aciduria type cblA";"Propionyl-CoA catabolism";"Defective MUT causes methylmalonic aciduria mut type";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
EAFF001490-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
EAFF004676-PA	5	Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
EAFF025974-PA	1	Reactome: R-HSA-1483255	"PI Metabolism"
EAFF023042-PA	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
EAFF007608-PA	6	Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
EAFF017363-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF000345-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EAFF013208-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
EAFF000189-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
EAFF004255-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EAFF028773-PA	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
EAFF013683-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
EAFF028169-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EAFF008363-PA	5	MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations II (plants)"
EAFF007345-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF007451-PA	7	MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179	"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Surfactant metabolism";"Adenine and adenosine salvage III";"Purine metabolism";"Purine deoxyribonucleosides degradation I"
EAFF012319-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF003359-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF006223-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF027513-PA	13	Reactome: R-HSA-182218;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-8964038	"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"Recycling pathway of L1";"MHC class II antigen presentation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"LDL clearance"
EAFF002565-PA	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
EAFF009023-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
EAFF023283-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF016979-PA	17	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
EAFF003776-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF003185-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
EAFF020805-PA	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
EAFF024011-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
EAFF005631-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
EAFF004284-PA	2	Reactome: R-HSA-156581;Reactome: R-HSA-5689880	"Methylation";"Ub-specific processing proteases"
EAFF004477-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF002704-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
EAFF006733-PA	7	Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-6784531	"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus"
EAFF021632-PA	14	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00260+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181	"Folate polyglutamylation";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Folate transformations I";"Glycine betaine degradation I";"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"One carbon pool by folate";"Photorespiration "
EAFF027332-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
EAFF016529-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
EAFF002488-PA	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
EAFF025415-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
EAFF011588-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF004104-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF013910-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF003095-PA	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
EAFF007629-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
EAFF023142-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EAFF028077-PA	1	Reactome: R-HSA-5578775	"Ion homeostasis"
EAFF002536-PA	40	KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-7779;MetaCyc: PWY-7656;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-6946;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-7654;MetaCyc: PWY-6944;MetaCyc: PWY-6863;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-5789;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-7401;MetaCyc: PWY-6883;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-5177;MetaCyc: PWY-5136;KEGG: 00930+4.2.1.17+1.1.1.35	"Lysine degradation";"Geraniol degradation";"Benzoyl-coa degradation I (aerobic)";"Valine, leucine and isoleucine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Methyl tert-butyl ether degradation";"Spodoptera littoralis pheromone biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Androstenedione degradation";"Pyruvate fermentation to hexanol (engineered)";"Tryptophan metabolism";"Propanoate metabolism";"Limonene and pinene degradation";"Fatty acid degradation";"Fatty acid elongation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid salvage";"Butanoate metabolism";"Benzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"2-methylpropene degradation";"Glutaryl-coa degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Caprolactam degradation"
EAFF023525-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF019389-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
EAFF025416-PA	16	Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-174178	"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
EAFF023847-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF021750-PA	1	Reactome: R-HSA-8849175	"Threonine catabolism"
EAFF020310-PA	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
EAFF005875-PA	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
EAFF006478-PA	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
EAFF000128-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
EAFF017592-PA	22	MetaCyc: PWY-6142;KEGG: 00010+5.3.1.9;KEGG: 00520+5.3.1.9;Reactome: R-HSA-6798695;Reactome: R-HSA-70263;MetaCyc: PWY-5054;MetaCyc: PWY-7385;MetaCyc: PWY-3801;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;MetaCyc: PWY-6981;Reactome: R-HSA-70171;Reactome: R-HSA-5628897;MetaCyc: PWY-7238;MetaCyc: PWY-7347;MetaCyc: PWY-621;MetaCyc: PWY-8013;MetaCyc: PWY-5514;MetaCyc: PWY-5384;MetaCyc: PWY-622;MetaCyc: PWY-6992	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neutrophil degranulation";"Gluconeogenesis";"D-sorbitol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"Chitin biosynthesis";"Glycolysis";"TP53 Regulates Metabolic Genes";"Sucrose biosynthesis II";"Sucrose biosynthesis III";"Sucrose degradation III (sucrose invertase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation IV (sucrose phosphorylase)";"Starch biosynthesis";"1,5-anhydrofructose degradation"
EAFF025627-PA	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
EAFF005321-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF014796-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
EAFF006683-PA	1	MetaCyc: PWY-6938	"NADH repair"
EAFF023245-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
EAFF021103-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF029265-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
EAFF027247-PA	21	Reactome: R-HSA-1169091;Reactome: R-HSA-1810476;Reactome: R-HSA-5603029;Reactome: R-HSA-1236974;Reactome: R-HSA-937039;Reactome: R-HSA-5357956;Reactome: R-HSA-933542;Reactome: R-HSA-2871837;Reactome: R-HSA-168927;Reactome: R-HSA-933543;Reactome: R-HSA-445989;Reactome: R-HSA-5684264;Reactome: R-HSA-5602636;Reactome: R-HSA-202424;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-5607764;Reactome: R-HSA-168638;Reactome: R-HSA-937041;Reactome: R-HSA-5603027;Reactome: R-HSA-9020702	"Activation of NF-kappaB in B cells";"RIP-mediated NFkB activation via ZBP1";"IkBA variant leads to EDA-ID";"ER-Phagosome pathway";"IRAK1 recruits IKK complex";"TNFR1-induced NFkappaB signaling pathway";"TRAF6 mediated NF-kB activation";"FCERI mediated NF-kB activation";"TICAM1, RIP1-mediated IKK complex recruitment";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKBKB deficiency causes SCID";"Downstream TCR signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"CLEC7A (Dectin-1) signaling";"NOD1/2 Signaling Pathway";"IKK complex recruitment mediated by RIP1";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"Interleukin-1 signaling"
EAFF008497-PA	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
EAFF005009-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
EAFF003054-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EAFF028287-PA	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
EAFF010612-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
EAFF027030-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
EAFF023432-PA	1	Reactome: R-HSA-140837	"Intrinsic Pathway of Fibrin Clot Formation"
EAFF018441-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
EAFF022021-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
EAFF011619-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF010696-PA	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
EAFF020965-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF010935-PA	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
EAFF011326-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF014377-PA	27	Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-5578749	"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs"
EAFF012305-PA	1	Reactome: R-HSA-5676934	"Protein repair"
EAFF006463-PA	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
EAFF003056-PA	14	Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-110312	"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Polymerase switching";"Dual Incision in GG-NER";"Translesion synthesis by REV1"
EAFF014929-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF022388-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF014398-PA	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF019581-PA	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
EAFF013928-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
EAFF003942-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
EAFF023071-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EAFF016527-PA	8	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF028747-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
EAFF006593-PA	7	MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702	"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I"
EAFF026020-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
EAFF000452-PA	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
EAFF007026-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
EAFF006421-PA	3	MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE"
EAFF013467-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EAFF021749-PA	1	Reactome: R-HSA-8849175	"Threonine catabolism"
EAFF015209-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
EAFF003167-PA	1	Reactome: R-HSA-350864	"Regulation of thyroid hormone activity"
EAFF003238-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF018303-PA	22	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7727;MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-7592;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7053;MetaCyc: PWY-8041;MetaCyc: PWY-7728;MetaCyc: PWY-5080;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7602	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
EAFF029469-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
EAFF015171-PA	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
EAFF028934-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EAFF009526-PA	4	Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494	"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV"
EAFF028625-PA	2	KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004	"Pentose phosphate pathway";"Entner-Doudoroff pathway I"
EAFF011876-PA	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
EAFF028725-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
EAFF005847-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF009547-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
EAFF017981-PA	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
EAFF019653-PA	7	MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
EAFF027118-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF029122-PA	14	Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128	"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling"
EAFF000440-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
EAFF003471-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF009017-PA	5	Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
EAFF009740-PA	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
EAFF028930-PA	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688	"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism"
EAFF026748-PA	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
EAFF028259-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
EAFF024386-PA	1	Reactome: R-HSA-1296061	"HCN channels"
EAFF002243-PA	4	Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440	"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling"
EAFF028132-PA	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
EAFF001227-PA	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
EAFF016884-PA	6	Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039	"Synthesis of PG";"Choline biosynthesis III";"Synthesis of PA";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
EAFF010962-PA	8	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-6798695;Reactome: R-HSA-8854518;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Neutrophil degranulation";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome"
EAFF005653-PA	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
EAFF023000-PA	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
EAFF025253-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
EAFF013225-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
EAFF017853-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
EAFF017210-PA	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
EAFF002498-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF000231-PA	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
EAFF005870-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF021102-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
EAFF006254-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF020835-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF027381-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
EAFF024329-PA	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
EAFF009215-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF011115-PA	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
EAFF008274-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF011051-PA	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
EAFF008096-PA	7	Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400	"Macroautophagy";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer"
EAFF011041-PA	7	Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;MetaCyc: PWY-7511	"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination"
EAFF014383-PA	4	Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
EAFF015147-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF018804-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF013420-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
EAFF004617-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF005869-PA	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
EAFF021876-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF001137-PA	16	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF019187-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF023320-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF019651-PA	7	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
EAFF009546-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF005457-PA	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
EAFF003789-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
EAFF004920-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF024238-PA	42	MetaCyc: PWY-7779;MetaCyc: PWY-7656;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6863;KEGG: 00640+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6583;MetaCyc: PWY-6944;MetaCyc: PWY-7654;MetaCyc: PWY-7401;MetaCyc: PWY-6883;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00627+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-5177	"Methyl tert-butyl ether degradation";"Spodoptera littoralis pheromone biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Lysine degradation";"Geraniol degradation";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to hexanol (engineered)";"Propanoate metabolism";"Tryptophan metabolism";"Limonene and pinene degradation";"Fatty acid degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid elongation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol I";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid salvage";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Aminobenzoate degradation";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Caprolactam degradation";"Benzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"2-methylpropene degradation";"Glutaryl-coa degradation"
EAFF024806-PA	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
EAFF009181-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
EAFF023953-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
EAFF019977-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF007476-PA	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6433	"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)"
EAFF011613-PA	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
EAFF007534-PA	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EAFF005571-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF004159-PA	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
EAFF027472-PA	8	KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1	"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism"
EAFF022466-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
EAFF007475-PA	4	MetaCyc: PWY-7164;MetaCyc: PWY-6927;KEGG: 00860+3.1.1.14;MetaCyc: PWY-5098	"Chlorophyll a degradation III";"Chlorophyll a degradation II";"Porphyrin and chlorophyll metabolism";"Chlorophyll a degradation I"
EAFF017969-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF002427-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EAFF007636-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
EAFF017167-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
EAFF023382-PA	2	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation"
EAFF021104-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
EAFF024009-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
EAFF012844-PA	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
EAFF017773-PA	29	Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-912446;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-68962	"HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex"
EAFF018623-PA	17	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression"
EAFF028707-PA	10	Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23	"Hyaluronan uptake and degradation";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation"
EAFF011220-PA	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation"
EAFF018712-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
EAFF021114-PA	14	Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4	"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Synthesis of PE";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism"
EAFF006868-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF004724-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF006323-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF020867-PA	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
EAFF013182-PA	57	Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-6798695;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5668541	"Separation of Sister Chromatids";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neutrophil degranulation";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"TNFR2 non-canonical NF-kB pathway"
EAFF014716-PA	1	Reactome: R-HSA-977443	"GABA receptor activation"
EAFF006466-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
EAFF009304-PA	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
EAFF012243-PA	11	MetaCyc: PWY-6596;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-6607;MetaCyc: PWY-5381;MetaCyc: PWY-5695;KEGG: 00230+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185	"Adenosine nucleotides degradation I";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I"
EAFF005035-PA	1	Reactome: R-HSA-5676934	"Protein repair"
EAFF007657-PA	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
EAFF020200-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
EAFF000243-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF001297-PA	6	MetaCyc: PWY-6317;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12	"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism"
EAFF002887-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF000236-PA	11	MetaCyc: PWY-5381;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-7821;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5	"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Purine metabolism"
EAFF022198-PA	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
EAFF027941-PA	7	Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346	"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Hedgehog ligand biogenesis"
EAFF004105-PA	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000170	"Molecules associated with elastic fibres";"ECM proteoglycans";"Integrin cell surface interactions";"Syndecan interactions"
EAFF014172-PA	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
EAFF010160-PA	4	MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
EAFF010725-PA	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
EAFF007703-PA	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo";"Human papillomavirus infection"
EAFF020283-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
EAFF003914-PA	12	MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism"
EAFF012079-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF006642-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
EAFF015924-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EAFF019167-PA	3	Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70895	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism"
EAFF007865-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF015329-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EAFF016227-PA	33	Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-5578749	"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"ISG15 antiviral mechanism";"snRNP Assembly";"Transcriptional regulation by small RNAs"
EAFF008555-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EAFF012831-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF005551-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
EAFF000438-PA	26	Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-5663220	"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Gap junction assembly";"Mitotic Prometaphase";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins"
EAFF003448-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
EAFF012650-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EAFF020865-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF015330-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
EAFF016325-PA	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
EAFF006361-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
EAFF017747-PA	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
EAFF026393-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF017516-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
EAFF017627-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF007548-PA	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
EAFF029718-PA	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
EAFF018461-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF024890-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
EAFF011788-PA	8	Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Recycling pathway of L1";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
EAFF023764-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF002948-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF019525-PA	3	Reactome: R-HSA-198693;Reactome: R-HSA-383280;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the nucleus";"Nuclear Receptor transcription pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
EAFF018192-PA	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
EAFF019491-PA	8	Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs"
EAFF018835-PA	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
EAFF026693-PA	4	MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism"
EAFF012748-PA	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
EAFF016291-PA	13	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;MetaCyc: PWY-7883	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II"
EAFF014122-PA	6	MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00750+4.3.3.6;KEGG: 00471+3.5.1.2;MetaCyc: PWY-6466;KEGG: 00220+3.5.1.2	"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Vitamin B6 metabolism";"D-Glutamine and D-glutamate metabolism";"Pyridoxal 5'-phosphate biosynthesis II";"Arginine biosynthesis"
EAFF028818-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
EAFF005259-PA	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
EAFF019866-PA	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
EAFF028195-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
EAFF011868-PA	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
EAFF010197-PA	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
EAFF022239-PA	8	Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-6798695;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-6803207	"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases"
EAFF007124-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
EAFF016670-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF026631-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
EAFF027003-PA	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
EAFF011874-PA	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
EAFF012538-PA	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
EAFF006712-PA	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
EAFF019595-PA	8	KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism"
EAFF007774-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
EAFF017643-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
EAFF013845-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF022931-PA	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
EAFF014255-PA	12	MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25	"Sulfite oxidation III";"Sulfate activation for sulfonation";"Selenocompound metabolism";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Sulfur metabolism";"Selenate reduction";"Sulfur metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism"
EAFF018798-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
EAFF020175-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF000226-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF012886-PA	14	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
EAFF028969-PA	2	Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2	"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway"
EAFF029438-PA	1	KEGG: 00500+2.4.1.15	"Starch and sucrose metabolism"
EAFF010136-PA	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
EAFF005820-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF004369-PA	7	Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-375276;Reactome: R-HSA-140837;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Platelet degranulation";"Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (i) signalling events";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
EAFF026840-PA	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
EAFF021577-PA	2	Reactome: R-HSA-5685938;Reactome: R-HSA-3108214	"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins"
EAFF009604-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
EAFF002941-PA	56	Reactome: R-HSA-5676590;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974	"NIK-->noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway"
EAFF018629-PA	3	KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3	"Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism"
EAFF019182-PA	1	Reactome: R-HSA-8951664	"Neddylation"
EAFF016353-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF001501-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF002713-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF024134-PA	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
EAFF001178-PA	26	Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467	"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs"
EAFF025354-PA	1	Reactome: R-HSA-6787639	"GDP-fucose biosynthesis"
EAFF007654-PA	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
EAFF025550-PA	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF004742-PA	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"HATs acetylate histones";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
EAFF019631-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF019587-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EAFF018460-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
EAFF023075-PA	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399	"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Aggrephagy"
EAFF004983-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
EAFF013823-PA	33	Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-69273;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-69656	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry"
EAFF023239-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EAFF011422-PA	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
EAFF001444-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EAFF007812-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF023463-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
EAFF000397-PA	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
EAFF009493-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF004657-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
EAFF006443-PA	5	Reactome: R-HSA-189451;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;MetaCyc: PWY-5189	"Heme biosynthesis";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)"
EAFF013241-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
EAFF027893-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
EAFF020630-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
EAFF020366-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF015390-PA	6	Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-912446	"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination"
EAFF013840-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
EAFF000610-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF021401-PA	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
EAFF015460-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF016952-PA	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Thermogenesis"
EAFF022250-PA	7	Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
EAFF006268-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF024267-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
EAFF017780-PA	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
EAFF002572-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
EAFF010994-PA	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629	"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
EAFF015741-PA	16	Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
EAFF006296-PA	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
EAFF013726-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
EAFF029242-PA	7	MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-7295;MetaCyc: PWY-6969;MetaCyc: PWY-7854	"D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
EAFF012568-PA	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
EAFF021848-PA	13	Reactome: R-HSA-1442490;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090	"Collagen degradation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"NCAM1 interactions";"Extracellular matrix organization";"Signaling by PDGF";"Collagen chain trimerization";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Laminin interactions";"Anchoring fibril formation";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures"
EAFF018394-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
EAFF025522-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EAFF009117-PA	6	Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110357;Reactome: R-HSA-110362	"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair"
EAFF008007-PA	6	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism"
EAFF024464-PA	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
EAFF000291-PA	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
EAFF004711-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
EAFF011622-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
EAFF024047-PA	7	MetaCyc: PWY-7238;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-5941;Reactome: R-HSA-70221;Reactome: R-HSA-6798695	"Sucrose biosynthesis II";"Starch degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation"
EAFF005071-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
EAFF013777-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
EAFF023210-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF012489-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
EAFF011465-PA	1	Reactome: R-HSA-446199	"Synthesis of Dolichyl-phosphate"
EAFF026363-PA	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
EAFF022569-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
EAFF008041-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
EAFF014400-PA	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation"
EAFF002971-PA	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
EAFF017939-PA	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
EAFF011801-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF023235-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
EAFF003157-PA	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
EAFF009335-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF020796-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
EAFF015417-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
EAFF021902-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
EAFF016875-PA	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
EAFF028428-PA	10	MetaCyc: PWY-7849;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;MetaCyc: PWY-5691;Reactome: R-HSA-2453902;Reactome: R-HSA-977225;Reactome: R-HSA-975634;MetaCyc: PWY-7394;Reactome: R-HSA-2453864	"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"Purine metabolism";"Urate conversion to allantoin I";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation";"Retinoid metabolism and transport";"Urate conversion to allantoin II";"Retinoid cycle disease events"
EAFF025431-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF003972-PA	10	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends"
EAFF014330-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
EAFF012251-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
EAFF014256-PA	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
EAFF001659-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EAFF014439-PA	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation"
EAFF025231-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF014225-PA	14	MetaCyc: PWY-5690;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-3781	"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)"
EAFF017295-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
EAFF022350-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
EAFF027641-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
EAFF017938-PA	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
EAFF021323-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
EAFF018739-PA	19	MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
EAFF005984-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
EAFF011612-PA	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
EAFF005749-PA	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
EAFF007051-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
EAFF002715-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
EAFF001574-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF019070-PA	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
EAFF001628-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
EAFF023674-PA	1	Reactome: R-HSA-8963693	"Aspartate and asparagine metabolism"
EAFF026164-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
EAFF017837-PA	9	MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"PLC beta mediated events"
EAFF005832-PA	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
EAFF005355-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
EAFF003426-PA	5	Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
EAFF027469-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
EAFF029668-PA	9	MetaCyc: PWY-5663;MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-6147;Reactome: R-HSA-1474151	"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
EAFF010676-PA	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
EAFF015322-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
EAFF005037-PA	5	KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"Folate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)"
EAFF005940-PA	8	Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
EAFF018936-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
EAFF024460-PA	6	Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
EAFF016130-PA	7	MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
EAFF006248-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF015538-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
EAFF028148-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
EAFF005061-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol"
EAFF018427-PA	4	MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism"
EAFF008032-PA	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
EAFF024986-PA	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
EAFF011656-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
EAFF017052-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF024432-PA	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
EAFF015917-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
EAFF024004-PA	1	Reactome: R-HSA-140837	"Intrinsic Pathway of Fibrin Clot Formation"
EAFF016915-PA	8	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK"
EAFF003055-PA	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human cytomegalovirus infection"
EAFF017836-PA	1	Reactome: R-HSA-74217	"Purine salvage"
EAFF013450-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
EAFF018236-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF010141-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
EAFF018725-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
EAFF025429-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
EAFF024617-PA	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
EAFF017845-PA	26	Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Cilium Assembly";"Kinesins";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin"
EAFF016929-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF006729-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
EAFF012199-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
EAFF016206-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
EAFF017555-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
EAFF026725-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF015323-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
EAFF009979-PA	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
EAFF020279-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
EAFF017743-PA	12	KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5133;MetaCyc: PWY-7118;MetaCyc: PWY-5132;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1	"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Propanoate metabolism"
EAFF016879-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
EAFF021274-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
EAFF024686-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
EAFF012563-PA	5	Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
EAFF023811-PA	16	Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
EAFF006108-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
EAFF002884-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
EAFF000850-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
EAFF007952-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
EAFF007372-PA	6	MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2	"ATP biosynthesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Mitochondrial protein import";"Oxidative phosphorylation"
EAFF008356-PA	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
EAFF019925-PA	3	Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation"
EAFF021576-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
EAFF009641-PA	3	Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858	"Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines"
EAFF022087-PA	6	Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642	"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
EAFF001503-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
EAFF011253-PA	9	MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12	"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms"
EAFF001387-PA	7	KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;MetaCyc: PWY-6385;MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6471	"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
EAFF014685-PA	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
EAFF000729-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
EAFF020710-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
EAFF023995-PA	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
EAFF009039-PA	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
EAFF008809-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
EAFF020132-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation"
EAFF005979-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
EAFF007784-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"