Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
FOCC003318-PA	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
FOCC000716-PA	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
FOCC005533-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC003726-PA	16	Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC008561-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC008551-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
FOCC001870-PA	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
FOCC008227-PA	13	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
FOCC003642-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC007924-PA	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
FOCC016675-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC015818-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
FOCC016992-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC013663-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC011773-PA	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
FOCC011133-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
FOCC000388-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC005394-PA	6	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation"
FOCC000279-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC006104-PA	5	Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912399	"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
FOCC012161-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
FOCC003127-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
FOCC011987-PA	57	Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-450408	"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
FOCC011883-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
FOCC016754-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
FOCC014871-PA	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
FOCC003859-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC001323-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
FOCC013324-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC003796-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC013506-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC000142-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC009014-PA	56	Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091	"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neddylation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells"
FOCC016100-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
FOCC001694-PA	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-8053	"Glycerolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II"
FOCC013167-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC000802-PA	12	Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-205043	"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus"
FOCC017939-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC013445-PA	4	MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
FOCC008689-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC004597-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
FOCC003133-PA	8	Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852	"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy"
FOCC015520-PA	9	MetaCyc: PWY-6118;MetaCyc: PWY-7411;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-5667	"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I"
FOCC007196-PA	7	MetaCyc: PWY-6906;MetaCyc: PWY-5514;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;Reactome: R-HSA-71336	"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Pentose phosphate pathway"
FOCC012637-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC000757-PA	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
FOCC002639-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC012827-PA	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
FOCC017598-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC011573-PA	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
FOCC014726-PA	7	Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2	"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation"
FOCC014315-PA	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
FOCC004410-PA	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex"
FOCC006874-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC000862-PA	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
FOCC005277-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC012565-PA	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
FOCC005072-PA	56	Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-187577	"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21"
FOCC002370-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC008736-PA	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
FOCC000795-PA	3	Reactome: R-HSA-8953750;Reactome: R-HSA-73772;Reactome: R-HSA-427389	"Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
FOCC006747-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC016862-PA	1	Reactome: R-HSA-5676934	"Protein repair"
FOCC013369-PA	10	Reactome: R-HSA-2142789;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5895;MetaCyc: PWY-5891;MetaCyc: PWY-5839;MetaCyc: PWY-5844;MetaCyc: PWY-5892;MetaCyc: PWY-5849	"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis"
FOCC015334-PA	4	MetaCyc: PWY-7111;KEGG: 00290+1.1.1.86;MetaCyc: PWY-5103;KEGG: 00770+1.1.1.86	"Pyruvate fermentation to isobutanol (engineered)";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis"
FOCC004746-PA	18	MetaCyc: PWY-5084;Reactome: R-HSA-5362517;KEGG: 00280+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00260+1.8.1.4;KEGG: 00010+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-71403;Reactome: R-HSA-204174;Reactome: R-HSA-71064;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00620+1.8.1.4	"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Valine, leucine and isoleucine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Branched-chain amino acid catabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Lysine degradation";"Propanoate metabolism";"Glycine degradation";"Citric acid cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine catabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism"
FOCC005924-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC009253-PA	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
FOCC014240-PA	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
FOCC002871-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC015927-PA	4	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37	"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism"
FOCC017759-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC013064-PA	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
FOCC008573-PA	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC002185-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC000501-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
FOCC006605-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC005126-PA	5	Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946	"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants"
FOCC014286-PA	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
FOCC013806-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
FOCC015470-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC016003-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
FOCC015825-PA	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
FOCC001831-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC003768-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
FOCC003025-PA	5	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
FOCC015639-PA	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
FOCC017548-PA	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
FOCC007877-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC002923-PB	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC012866-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
FOCC014795-PA	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
FOCC016047-PA	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
FOCC012416-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC004727-PA	5	Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838	"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO"
FOCC017755-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC012744-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC012762-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC000920-PA	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
FOCC003012-PA	16	Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC003947-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC004019-PA	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
FOCC017410-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC004910-PA	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
FOCC015285-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
FOCC011027-PA	7	MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11	"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism"
FOCC017655-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
FOCC016452-PA	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
FOCC007353-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC011290-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
FOCC003448-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC010745-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
FOCC006780-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
FOCC006543-PA	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
FOCC011396-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
FOCC008735-PA	15	KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-6886;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6901	"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Rubisco shunt";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation"
FOCC014146-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC014607-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC004572-PA	52	Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813	"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Neddylation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids"
FOCC009555-PA	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
FOCC012839-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC001419-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC000298-PA	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC011474-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC015332-PA	11	MetaCyc: PWY-5939;MetaCyc: PWY-5101;KEGG: 00290+2.2.1.6;MetaCyc: PWY-5938;KEGG: 00650+2.2.1.6;MetaCyc: PWY-6389;MetaCyc: PWY-7111;KEGG: 00770+2.2.1.6;MetaCyc: PWY-5103;KEGG: 00660+2.2.1.6;MetaCyc: PWY-5104	"Pyruvate fermentation to (R)-acetoin II";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"Pyruvate fermentation to (R)-acetoin I";"Butanoate metabolism";"Pyruvate fermentation to (S)-acetoin";"Pyruvate fermentation to isobutanol (engineered)";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III";"C5-Branched dibasic acid metabolism";"L-isoleucine biosynthesis IV"
FOCC000430-PA	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
FOCC015135-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC008741-PA	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
FOCC015505-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
FOCC007487-PA	2	Reactome: R-HSA-375276;Reactome: R-HSA-418555	"Peptide ligand-binding receptors";"G alpha (s) signalling events"
FOCC015611-PA	16	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC012270-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC008904-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
FOCC010817-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC000241-PA	14	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)"
FOCC001352-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC010926-PA	5	Reactome: R-HSA-6798695;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883	"Neutrophil degranulation";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG"
FOCC007668-PA	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
FOCC007106-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC003165-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
FOCC015670-PA	5	Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168	"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)"
FOCC013356-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC015816-PA	1	KEGG: 00970+6.1.1.15	"Aminoacyl-tRNA biosynthesis"
FOCC004024-PA	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
FOCC009284-PA	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC005952-PA	6	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state"
FOCC013122-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC009076-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
FOCC008316-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC001285-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC004183-PA	10	Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408	"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation"
FOCC012195-PA	12	MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783	"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Ether lipid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation"
FOCC009248-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
FOCC001975-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
FOCC013777-PA	31	MetaCyc: PWY-8012;MetaCyc: PWY-4381;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-6519;MetaCyc: PWY-5142;Reactome: R-HSA-163765;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;MetaCyc: PWY-5971;MetaCyc: PWY-8049;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-5994;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-5973;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWY-7723	"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Bryostatin biosynthesis";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence"
FOCC002291-PA	14	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4	"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Ether lipid metabolism";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism"
FOCC007266-PA	12	KEGG: 00970+2.1.2.9;Reactome: R-HSA-196780;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6613;MetaCyc: PWY-6122;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817	"Aminoacyl-tRNA biosynthesis";"Biotin transport and metabolism";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"One carbon pool by folate";"One carbon pool by folate";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
FOCC002261-PA	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
FOCC013284-PA	1	Reactome: R-HSA-8964038	"LDL clearance"
FOCC004155-PA	16	Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-983168	"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC005360-PA	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
FOCC003177-PA	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
FOCC006113-PA	40	Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823	"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex"
FOCC003329-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
FOCC000816-PA	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
FOCC016678-PA	5	KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3	"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes"
FOCC004614-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC009216-PA	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
FOCC013643-PA	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC015117-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC017914-PA	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
FOCC012674-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC011544-PA	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
FOCC014953-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC015710-PA	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
FOCC011550-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC004180-PA	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
FOCC008394-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
FOCC007244-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
FOCC004921-PA	4	Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
FOCC015969-PA	4	Reactome: R-HSA-70895;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-1296072	"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Voltage gated Potassium channels"
FOCC000091-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
FOCC017766-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC015625-PA	56	Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-2467813	"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"UCH proteinases";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids"
FOCC004411-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC006271-PA	24	Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-456926;Reactome: R-HSA-418555	"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"G-protein activation";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events"
FOCC005253-PA	5	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-5694530;Reactome: R-HSA-9609523	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Cargo concentration in the ER";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
FOCC000364-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC004382-PA	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC013860-PB	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC014730-PA	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
FOCC000155-PA	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
FOCC001114-PA	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress"
FOCC007436-PA	3	Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis"
FOCC011743-PA	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
FOCC007099-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC008852-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
FOCC013798-PA	14	MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7589	"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)"
FOCC010700-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
FOCC014166-PA	13	KEGG: 00230+3.6.1.66;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;Reactome: R-HSA-74259;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187	"Purine metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Purine catabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
FOCC014790-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC009033-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
FOCC006156-PA	27	Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-191859	"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"SUMOylation of RNA binding proteins";"snRNP Assembly"
FOCC015357-PA	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
FOCC003936-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
FOCC015951-PA	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
FOCC011724-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC001640-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
FOCC003073-PA	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
FOCC003136-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC000181-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC014215-PA	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
FOCC006614-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC001263-PA	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
FOCC006066-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
FOCC015288-PA	15	Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607	"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends"
FOCC001999-PA	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
FOCC009160-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
FOCC014734-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
FOCC013807-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
FOCC011873-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
FOCC016175-PA	1	Reactome: R-HSA-200425	"Carnitine metabolism"
FOCC002916-PA	5	MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Protein ubiquitination";"Regulation of PTEN stability and activity";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
FOCC009551-PA	4	Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282	"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
FOCC012748-PA	16	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-167152	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Neddylation";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat"
FOCC007861-PA	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
FOCC001739-PA	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
FOCC008997-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
FOCC015794-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC016099-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC017568-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC001329-PA	6	KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism"
FOCC004952-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC005430-PA	4	MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7849	"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin III"
FOCC017109-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC002678-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
FOCC007918-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
FOCC000899-PA	7	KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
FOCC001635-PA	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
FOCC000375-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
FOCC013918-PA	1	Reactome: R-HSA-70171	"Glycolysis"
FOCC013545-PA	5	Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-1834941	"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses"
FOCC017923-PA	11	Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604	"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling"
FOCC014483-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC000571-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
FOCC001071-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC000892-PA	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
FOCC005535-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC002013-PA	29	Reactome: R-HSA-5693616;Reactome: R-HSA-5696395;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-912446;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5696400	"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"Meiotic recombination";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Dual Incision in GG-NER"
FOCC002767-PA	3	Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078	"GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
FOCC009282-PA	6	Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex"
FOCC017760-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC003413-PA	16	Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC017577-PA	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
FOCC016984-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC017941-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC015647-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC016938-PA	8	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation"
FOCC011802-PA	30	Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-2564830;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-167162	"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic iron-sulfur cluster assembly";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape"
FOCC003620-PA	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC013633-PA	6	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-416993	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors"
FOCC007385-PA	14	Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418	"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex"
FOCC005009-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
FOCC003108-PA	14	MetaCyc: PWY-5104;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00290+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00770+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5108;MetaCyc: PWY-7767;MetaCyc: PWY-5101;MetaCyc: PWY-5076	"L-isoleucine biosynthesis IV";"Cysteine and methionine metabolism";"L-valine degradation II";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"Valine, leucine and isoleucine biosynthesis";"Valine, leucine and isoleucine degradation";"Pantothenate and CoA biosynthesis";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"L-leucine degradation III"
FOCC013574-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
FOCC017534-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC004498-PA	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
FOCC017845-PA	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
FOCC004506-PA	1	Reactome: R-HSA-5676934	"Protein repair"
FOCC014451-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC009602-PA	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
FOCC000385-PA	16	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC003505-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC010788-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC004564-PA	3	Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
FOCC011240-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC015030-PA	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
FOCC004384-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
FOCC015226-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC003940-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC004449-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC007968-PA	6	MetaCyc: PWY-6906;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-7395;MetaCyc: PWY-7077	"Chitin derivatives degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation"
FOCC000258-PA	6	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC001506-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC004723-PA	13	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC004040-PA	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
FOCC014586-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC002672-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
FOCC004604-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC003072-PA	12	Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression"
FOCC005536-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC013946-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC012085-PA	6	Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-434316	"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
FOCC006598-PA	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
FOCC005643-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC002315-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC009084-PA	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC002355-PA	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
FOCC003010-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC001171-PA	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
FOCC010965-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC001136-PA	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)"
FOCC007729-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC000845-PA	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
FOCC002100-PA	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
FOCC011703-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC004311-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC009266-PA	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
FOCC015122-PA	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation"
FOCC009359-PA	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
FOCC011918-PA	14	MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-7587	"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
FOCC015489-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC005834-PA	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
FOCC016237-PA	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1474228;Reactome: R-HSA-6803157	"Collagen degradation";"Degradation of the extracellular matrix";"Antimicrobial peptides"
FOCC011244-PA	9	Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68952	"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"DNA replication initiation"
FOCC007688-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC014777-PA	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
FOCC003402-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC012397-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
FOCC001413-PA	5	KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32	"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
FOCC000558-PA	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
FOCC005875-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
FOCC011505-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
FOCC002962-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
FOCC008886-PA	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
FOCC000201-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
FOCC006236-PA	7	MetaCyc: PWY-7210;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7197	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation"
FOCC012206-PA	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
FOCC016364-PA	7	MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"ATP biosynthesis";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
FOCC013452-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC004551-PA	7	Reactome: R-HSA-2408522;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15	"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis"
FOCC000694-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC008323-PA	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC000645-PA	12	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Macroautophagy";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"mTOR signaling pathway"
FOCC014659-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC000946-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
FOCC005851-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC011539-PA	4	Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis"
FOCC010881-PA	3	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC002108-PA	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
FOCC001245-PA	56	Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins"
FOCC006801-PA	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402	"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex"
FOCC003254-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
FOCC014894-PA	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
FOCC005965-PA	12	Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408	"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation"
FOCC001236-PA	9	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
FOCC007004-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC002017-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC015224-PA	13	KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857	"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation"
FOCC013804-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
FOCC000948-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
FOCC008381-PA	7	Reactome: R-HSA-1483213;MetaCyc: PWY-7886;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-3385	"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Choline biosynthesis I"
FOCC012015-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC012284-PA	1	Reactome: R-HSA-1483148	"Synthesis of PG"
FOCC001864-PA	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
FOCC007537-PA	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
FOCC000178-PA	3	Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation"
FOCC011660-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
FOCC015101-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC011723-PA	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
FOCC006420-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC001173-PA	18	KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1	"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis"
FOCC004381-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC006895-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
FOCC015434-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC017376-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC007097-PA	10	KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41	"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism"
FOCC010753-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
FOCC017426-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC007859-PA	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
FOCC011163-PA	7	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids"
FOCC004789-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
FOCC000222-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
FOCC005915-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC008256-PA	15	Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167246	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript"
FOCC009325-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC005440-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC004291-PA	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events"
FOCC017012-PA	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
FOCC000471-PA	32	Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-8851708;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167160	"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
FOCC002949-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC005531-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC001205-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC013326-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC013570-PA	6	Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
FOCC000964-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC007607-PA	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC005527-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC004924-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
FOCC002556-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC002906-PA	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
FOCC000586-PA	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
FOCC008276-PA	4	MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
FOCC012487-PA	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
FOCC002326-PA	52	Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-167158;Reactome: R-HSA-1834949;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-8851708;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-73980;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Signaling by FGFR2 IIIa TM";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Termination";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation"
FOCC017023-PA	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
FOCC002316-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC015729-PA	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)"
FOCC005903-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC005397-PA	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
FOCC013940-PA	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
FOCC013031-PA	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
FOCC017152-PA	5	MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
FOCC001286-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC017350-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC014432-PA	4	Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040	"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation"
FOCC014621-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
FOCC004586-PA	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
FOCC004347-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
FOCC001393-PA	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
FOCC015114-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC001373-PA	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
FOCC003618-PA	33	Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-69202;Reactome: R-HSA-5696395;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-69656;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-6782135	"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Cyclin E associated events during G1/S transition";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A:Cdk2-associated events at S phase entry";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER"
FOCC003178-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC008743-PA	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
FOCC003215-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC016664-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC009060-PA	27	Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159231	"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript"
FOCC002820-PA	12	Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
FOCC018029-PA	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
FOCC012114-PA	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC016831-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC007105-PA	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
FOCC011514-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC009221-PA	2	KEGG: 00780+6.3.3.3;MetaCyc: PWY-7380	"Biotin metabolism";"Biotin biosynthesis from 8-amino-7-oxononanoate II"
FOCC013335-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC007593-PA	5	KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;Reactome: R-HSA-6798695	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation"
FOCC002573-PA	8	Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
FOCC006108-PB	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
FOCC001646-PA	4	MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
FOCC015828-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
FOCC000438-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC000185-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
FOCC004887-PA	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
FOCC017635-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
FOCC005912-PA	22	Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-432142	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL"
FOCC004452-PA	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
FOCC013405-PA	5	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-2426168	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)"
FOCC002898-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
FOCC004028-PA	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
FOCC000456-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC012357-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
FOCC017045-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC011800-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1"
FOCC001812-PA	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
FOCC009632-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
FOCC000947-PA	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
FOCC000722-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
FOCC017071-PA	26	Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497	"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"Cilium Assembly";"MHC class II antigen presentation";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
FOCC013548-PA	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
FOCC001203-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC015826-PA	2	Reactome: R-HSA-446205;KEGG: 00300+2.3.1.117	"Synthesis of GDP-mannose";"Lysine biosynthesis"
FOCC012538-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
FOCC011338-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC011707-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC004450-PA	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
FOCC017758-PA	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
FOCC011690-PA	11	Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation"
FOCC013943-PA	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
FOCC014336-PA	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
FOCC008681-PA	2	Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
FOCC017349-PA	7	KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484	"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
FOCC004984-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
FOCC006152-PA	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
FOCC016110-PA	1	Reactome: R-HSA-8964572	"Lipid particle organization"
FOCC002649-PA	16	Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-196025	"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"Formation of annular gap junctions"
FOCC004774-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC007404-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC016529-PA	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis"
FOCC004828-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
FOCC012019-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC004484-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
FOCC014848-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC012594-PA	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC014888-PA	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
FOCC016987-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC006002-PA	1	Reactome: R-HSA-8963693	"Aspartate and asparagine metabolism"
FOCC007933-PA	14	MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7602	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
FOCC015852-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC004307-PA	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC015339-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
FOCC007124-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC017096-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC001278-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC007899-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
FOCC004386-PA	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
FOCC001193-PA	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
FOCC016084-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC016973-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
FOCC000432-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC005514-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC002850-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
FOCC013017-PA	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1296052	"Phase 4 - resting membrane potential";"Ca2+ activated K+ channels"
FOCC002753-PA	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-2151201	"UCH proteinases";"HATs acetylate histones";"Transcriptional activation of mitochondrial biogenesis"
FOCC013320-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC005927-PA	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
FOCC002923-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC012332-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
FOCC005564-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC008903-PA	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
FOCC016288-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC017946-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC014266-PA	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
FOCC001446-PA	27	Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638	"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins"
FOCC003938-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
FOCC005029-PA	10	Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736	"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors"
FOCC007355-PA	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
FOCC013938-PA	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
FOCC006158-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
FOCC001491-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC005947-PB	9	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection"
FOCC017298-PA	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
FOCC001688-PA	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
FOCC004995-PA	9	MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series"
FOCC004907-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
FOCC015057-PA	19	Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-432142	"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Chylomicron assembly";"VLDL assembly";"LDL remodeling";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"LDL clearance";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"VLDL clearance";"Post-translational protein phosphorylation";"Platelet sensitization by LDL"
FOCC016086-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
FOCC006047-PA	57	Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276	"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint"
FOCC009204-PA	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
FOCC006853-PA	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
FOCC013598-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
FOCC000502-PA	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
FOCC005129-PA	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
FOCC004867-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC008608-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC003575-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC016450-PA	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
FOCC011306-PA	8	Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952	"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation"
FOCC001405-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
FOCC002877-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC006892-PA	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
FOCC002593-PA	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
FOCC012621-PA	5	Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3"
FOCC001469-PA	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
FOCC005981-PA	7	Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-201681	"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"RHO GTPases Activate Formins";"TCF dependent signaling in response to WNT"
FOCC000703-PA	3	Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542	"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation"
FOCC002808-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
FOCC005661-PA	17	Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091;Reactome: R-HSA-937072;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-9645460	"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ca2+ pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ub-specific processing proteases";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway"
FOCC016428-PA	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
FOCC001889-PA	9	Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-416482	"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Rho GTPase cycle";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events"
FOCC012050-PA	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
FOCC016431-PA	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
FOCC002821-PA	13	Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757;Reactome: R-HSA-3371571;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604	"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of TP53 Degradation";"HSF1-dependent transactivation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling"
FOCC015836-PA	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
FOCC003503-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
FOCC002461-PA	11	Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-163359	"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation"
FOCC014322-PA	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
FOCC011674-PA	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation"
FOCC008872-PA	6	Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
FOCC001487-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC011177-PA	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
FOCC003228-PA	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519	"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"Estrogen-dependent gene expression"
FOCC016581-PA	31	MetaCyc: PWY-7664;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-4381;MetaCyc: PWY-7858;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-5994;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-5971;MetaCyc: PWY-8049;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5367	"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Fatty acid biosynthesis";"Bryostatin biosynthesis";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis"
FOCC008894-PA	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
FOCC002131-PA	21	Reactome: R-HSA-5607764;Reactome: R-HSA-5603029;Reactome: R-HSA-975144;Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-168927;Reactome: R-HSA-1169091;Reactome: R-HSA-5603027;Reactome: R-HSA-937039;Reactome: R-HSA-202424;Reactome: R-HSA-5602636;Reactome: R-HSA-933543;Reactome: R-HSA-1236974;Reactome: R-HSA-5357905;Reactome: R-HSA-5357956;Reactome: R-HSA-933542;Reactome: R-HSA-937041;Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264	"CLEC7A (Dectin-1) signaling";"IkBA variant leads to EDA-ID";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TICAM1, RIP1-mediated IKK complex recruitment";"Activation of NF-kappaB in B cells";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"IRAK1 recruits IKK complex";"Downstream TCR signaling";"IKBKB deficiency causes SCID";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"ER-Phagosome pathway";"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6 mediated NF-kB activation";"IKK complex recruitment mediated by RIP1";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
FOCC002986-PA	179	Reactome: R-HSA-5696400;Reactome: R-HSA-9645460;Reactome: R-HSA-9033241;Reactome: R-HSA-445989;Reactome: R-HSA-168927;Reactome: R-HSA-8866654;Reactome: R-HSA-2173788;Reactome: R-HSA-3785653;Reactome: R-HSA-174113;Reactome: R-HSA-5685942;Reactome: R-HSA-8854050;Reactome: R-HSA-975957;Reactome: R-HSA-5656169;Reactome: R-HSA-6781827;Reactome: R-HSA-5632684;Reactome: R-HSA-936440;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-5357956;Reactome: R-HSA-5689877;Reactome: R-HSA-4641263;Reactome: R-HSA-917937;Reactome: R-HSA-1253288;Reactome: R-HSA-349425;Reactome: R-HSA-6804760;Reactome: R-HSA-1169408;Reactome: R-HSA-5684264;Reactome: R-HSA-5668541;Reactome: R-HSA-174184;Reactome: R-HSA-9010553;Reactome: R-HSA-5655862;Reactome: R-HSA-9633012;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-2122947;Reactome: R-HSA-6782135;Reactome: R-HSA-2565942;Reactome: R-HSA-205043;Reactome: R-HSA-450302;Reactome: R-HSA-5678895;Reactome: R-HSA-72706;Reactome: R-HSA-9604323;Reactome: R-HSA-6782210;Reactome: R-HSA-912631;Reactome: R-HSA-174154;Reactome: R-HSA-6791226;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-2559582;Reactome: R-HSA-5654733;Reactome: R-HSA-162588;Reactome: R-HSA-382556;Reactome: R-HSA-9637628;Reactome: R-HSA-2559580;Reactome: R-HSA-209543;Reactome: R-HSA-937041;Reactome: R-HSA-400253;Reactome: R-HSA-2979096;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8948747;Reactome: R-HSA-69017;Reactome: R-HSA-201681;Reactome: R-HSA-2559585;Reactome: R-HSA-1295596;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-5693607;Reactome: R-HSA-937072;Reactome: R-HSA-202424;Reactome: R-HSA-2173795;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-8866652;Reactome: R-HSA-168928;Reactome: R-HSA-174178;Reactome: R-HSA-5656121;Reactome: R-HSA-8849469;Reactome: R-HSA-5676590;Reactome: R-HSA-72689;Reactome: R-HSA-69601;Reactome: R-HSA-9636383;Reactome: R-HSA-917729;Reactome: R-HSA-8863795;Reactome: R-HSA-156827;Reactome: R-HSA-175474;Reactome: R-HSA-8941858;Reactome: R-HSA-1236382;Reactome: R-HSA-5610785;Reactome: R-HSA-5654732;Reactome: R-HSA-69541;Reactome: R-HSA-975144;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-6781823;Reactome: R-HSA-936964;Reactome: R-HSA-72764;Reactome: R-HSA-532668;Reactome: R-HSA-937039;Reactome: R-HSA-9013973;Reactome: R-HSA-6804757;Reactome: R-HSA-1358803;Reactome: R-HSA-977225;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-5675221;Reactome: R-HSA-8875360;Reactome: R-HSA-5654727;Reactome: R-HSA-179409;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-182971;Reactome: R-HSA-9646399;Reactome: R-HSA-156902;Reactome: R-HSA-3134975;Reactome: R-HSA-975110;Reactome: R-HSA-3322077;Reactome: R-HSA-5357905;Reactome: R-HSA-975163;Reactome: R-HSA-2173796;Reactome: R-HSA-2691232;Reactome: R-HSA-901032;Reactome: R-HSA-5696394;Reactome: R-HSA-8948751;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-5675482;Reactome: R-HSA-5696397;Reactome: R-HSA-8876493;Reactome: R-HSA-8856825;Reactome: R-HSA-8939902;Reactome: R-HSA-5689896;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-192823;Reactome: R-HSA-6807004;Reactome: R-HSA-6804756;Reactome: R-HSA-2173791;Reactome: R-HSA-174490;Reactome: R-HSA-5689603;Reactome: R-HSA-174048;Reactome: R-HSA-9613829;Reactome: R-HSA-2871837;Reactome: R-HSA-5696395;Reactome: R-HSA-9020702;Reactome: R-HSA-110320;Reactome: R-HSA-2122948;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-937042;Reactome: R-HSA-68949;Reactome: R-HSA-8856828;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-9615710;Reactome: R-HSA-3769402;Reactome: R-HSA-5689880;Reactome: R-HSA-110312;Reactome: R-HSA-209560;Reactome: R-HSA-69231;Reactome: R-HSA-5205685;Reactome: R-HSA-1236974;Reactome: R-HSA-2408557;Reactome: R-HSA-2672351;Reactome: R-HSA-6783310;Reactome: R-HSA-5693565;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2644606;Reactome: R-HSA-195253;Reactome: R-HSA-9014325;Reactome: R-HSA-5654726;Reactome: R-HSA-5689901	"Dual Incision in GG-NER";"Alpha-protein kinase 1 signaling pathway";"Peroxisomal protein import";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1, RIP1-mediated IKK complex recruitment";"E3 ubiquitin ligases ubiquitinate target proteins";"Downregulation of TGF-beta receptor signaling";"Myoclonic epilepsy of Lafora";"SCF-beta-TrCP mediated degradation of Emi1";"HDR through Homologous Recombination (HRR)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Termination of translesion DNA synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Hedgehog 'on' state";"Negative regulators of DDX58/IFIH1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"TNFR1-induced NFkappaB signaling pathway";"Josephin domain DUBs";"Regulation of FZD by ubiquitination";"Iron uptake and transport";"Downregulation of ERBB4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of TP53 Activity through Methylation";"ISG15 antiviral mechanism";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TNFR2 non-canonical NF-kB pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of expression of SLITs and ROBOs";"Translesion synthesis by POLK";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"G2/M Checkpoints";"Degradation of AXIN";"NOTCH1 Intracellular Domain Regulates Transcription";"Dual incision in TC-NER";"Regulation of PLK1 Activity at G2/M Transition";"NRIF signals cell death from the nucleus";"activated TAK1 mediates p38 MAPK activation";"Defective CFTR causes cystic fibrosis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Negative regulation of NOTCH4 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of signaling by CBL";"APC/C:Cdc20 mediated degradation of Securin";"Major pathway of rRNA processing in the nucleolus and cytosol";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR4 signaling";"Budding and maturation of HIV virion";"ABC-family proteins mediated transport";"Modulation by Mtb of host immune system";"Oxidative Stress Induced Senescence";"p75NTR recruits signalling complexes";"IKK complex recruitment mediated by RIP1";"Circadian Clock";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Regulation of PTEN localization";"CDK-mediated phosphorylation and removal of Cdc6";"TCF dependent signaling in response to WNT";"Oncogene Induced Senescence";"Spry regulation of FGF signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Processing of DNA double-strand break ends";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Downstream TCR signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Translesion synthesis by POLI";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"NIK-->noncanonical NF-kB signaling";"Formation of a pool of free 40S subunits";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Downregulation of ERBB2 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Assembly Of The HIV Virion";"Regulation of RUNX3 expression and activity";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of FGFR3 signaling";"Stabilization of p53";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Formation of TC-NER Pre-Incision Complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Eukaryotic Translation Termination";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"IRAK1 recruits IKK complex";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of TP53 Degradation";"Downregulation of ERBB2:ERBB3 signaling";"Amyloid fiber formation";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Negative regulation of MAPK pathway";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of FGFR2 signaling";"APC-Cdc20 mediated degradation of Nek2A";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"EGFR downregulation";"Aggrephagy";"Peptide chain elongation";"Regulation of innate immune responses to cytosolic DNA";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Glycogen synthesis";"Regulation of TNFR1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"ER Quality Control Compartment (ERQC)";"DNA Damage Recognition in GG-NER";"Regulation of PTEN stability and activity";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of necroptotic cell death";"Gap-filling DNA repair synthesis and ligation in GG-NER";"InlA-mediated entry of Listeria monocytogenes into host cells";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of RUNX2 expression and activity";"Ovarian tumor domain proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Viral mRNA Translation";"Negative regulation of MET activity";"Regulation of TP53 Activity through Phosphorylation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Membrane binding and targetting of GAG proteins";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Cyclin B";"Chaperone Mediated Autophagy";"FCERI mediated NF-kB activation";"Formation of Incision Complex in GG-NER";"Interleukin-1 signaling";"Translesion Synthesis by POLH";"Activated NOTCH1 Transmits Signal to the Nucleus";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"IRAK2 mediated activation of TAK1 complex";"Orc1 removal from chromatin";"Clathrin-mediated endocytosis";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Late endosomal microautophagy";"Deactivation of the beta-catenin transactivating complex";"Ub-specific processing proteases";"Translesion synthesis by REV1";"NF-kB is activated and signals survival";"Cyclin D associated events in G1";"Pink/Parkin Mediated Mitophagy";"ER-Phagosome pathway";"Selenocysteine synthesis";"Stimuli-sensing channels";"Fanconi Anemia Pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Negative regulation of FGFR1 signaling";"Metalloprotease DUBs"
FOCC002657-PA	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC001187-PA	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
FOCC013997-PA	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
FOCC001276-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC017204-PA	9	MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series"
FOCC015129-PA	8	Reactome: R-HSA-4641263;Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-8856825;Reactome: R-HSA-5340588;Reactome: R-HSA-5099900;Reactome: R-HSA-373080;Reactome: R-HSA-8856828	"Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins";"Ca2+ pathway";"Cargo recognition for clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)";"Clathrin-mediated endocytosis"
FOCC009552-PA	11	Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway"
FOCC000468-PA	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
FOCC014288-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
FOCC007601-PA	9	Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
FOCC004348-PA	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
FOCC004917-PA	1	MetaCyc: PWY-7379	"Mrna capping II"
FOCC006080-PA	22	MetaCyc: PWY-621;Reactome: R-HSA-5628897;KEGG: 00500+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-5054;KEGG: 00010+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-7385;MetaCyc: PWY-5514;MetaCyc: PWY-3801;KEGG: 00520+5.3.1.9;MetaCyc: PWY-6142;MetaCyc: PWY-6981;Reactome: R-HSA-70171;MetaCyc: PWY-7238;KEGG: 00030+5.3.1.9;Reactome: R-HSA-70263;MetaCyc: PWY-622;MetaCyc: PWY-5384;Reactome: R-HSA-6798695;MetaCyc: PWY-6992;MetaCyc: PWY-5659	"Sucrose degradation III (sucrose invertase)";"TP53 Regulates Metabolic Genes";"Starch and sucrose metabolism";"Sucrose biosynthesis III";"D-sorbitol biosynthesis I";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Chitin biosynthesis";"Glycolysis";"Sucrose biosynthesis II";"Pentose phosphate pathway";"Gluconeogenesis";"Starch biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"Neutrophil degranulation";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis"
FOCC001896-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC014416-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC014059-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
FOCC003731-PA	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
FOCC000386-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC014858-PA	8	KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-163754;Reactome: R-HSA-6791462;Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-6791055	"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P"
FOCC008026-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
FOCC016601-PA	16	Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-179409	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A"
FOCC013556-PA	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
FOCC017813-PA	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
FOCC007857-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC007863-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC001704-PA	7	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
FOCC005827-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC007225-PA	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
FOCC007096-PA	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
FOCC002139-PA	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
FOCC005539-PA	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
FOCC006831-PB	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC002303-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC013371-PA	4	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
FOCC017887-PA	7	Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation"
FOCC011272-PA	9	MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-6142;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1	"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
FOCC011125-PA	7	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
FOCC002588-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
FOCC004996-PA	4	MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II"
FOCC005043-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC009116-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
FOCC011284-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
FOCC005005-PA	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
FOCC014861-PA	2	Reactome: R-HSA-379726;MetaCyc: PWY-7884	"Mitochondrial tRNA aminoacylation";"Lipoprotein posttranslational modification"
FOCC011843-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
FOCC004217-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
FOCC011127-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC007393-PA	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
FOCC013362-PA	25	Reactome: R-HSA-8939256;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-8877330;Reactome: R-HSA-8934593;Reactome: R-HSA-8949275;Reactome: R-HSA-8939247;Reactome: R-HSA-8931987;Reactome: R-HSA-8941332;Reactome: R-HSA-8941333;Reactome: R-HSA-9616222;Reactome: R-HSA-8951911;Reactome: R-HSA-8939236;Reactome: R-HSA-8941326;Reactome: R-HSA-8951936;Reactome: R-HSA-8939243;Reactome: R-HSA-8939245;Reactome: R-HSA-8940973;Reactome: R-HSA-8939246;Reactome: R-HSA-8941858;Reactome: R-HSA-8935964;Reactome: R-HSA-9018519;Reactome: R-HSA-8939242;Reactome: R-HSA-8936459;Reactome: R-HSA-8941284	"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX1 Expression and Activity";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates bone development";"RUNX3 regulates p14-ARF";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity";"RUNX1 regulates expression of components of tight junctions";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates chondrocyte maturation"
FOCC011555-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC012925-PA	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
FOCC006365-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC008531-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC003988-PA	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
FOCC001371-PA	6	Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-110362	"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair"
FOCC005809-PA	5	Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407	"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
FOCC015609-PA	12	Reactome: R-HSA-111464;KEGG: 00030+1.1.99.3;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;MetaCyc: PWY-7165;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Pentose phosphate pathway";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Formation of apoptosome";"L-ascorbate biosynthesis VI (engineered pathway)";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
FOCC006934-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
FOCC005379-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
FOCC005981-PB	7	Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-5663220	"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins"
FOCC012718-PA	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC001727-PA	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
FOCC002647-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC012875-PA	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
FOCC009380-PA	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
FOCC005885-PA	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
FOCC004706-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC012009-PA	9	Reactome: R-HSA-9657050;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9656255;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Defective OGG1 Localization";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Defective OGG1 Substrate Binding";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
FOCC018020-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC005855-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC001156-PA	24	Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-8964616	"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G-protein activation";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42"
FOCC000442-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC012763-PA	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
FOCC002397-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC004385-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
FOCC005930-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC004892-PA	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
FOCC017741-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC000738-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC003501-PA	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
FOCC003651-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC016387-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC000160-PA	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
FOCC004076-PA	4	Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852	"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy"
FOCC009251-PA	5	MetaCyc: PWY-6167;MetaCyc: PWY-6168;Reactome: R-HSA-196757;KEGG: 00740+3.5.4.26+1.1.1.193;MetaCyc: PWY-7991	"Flavin biosynthesis II (archaea)";"Flavin biosynthesis III (fungi)";"Metabolism of folate and pterines";"Riboflavin metabolism";"Toxoflavin biosynthesis"
FOCC017370-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
FOCC006283-PA	15	Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897	"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes"
FOCC006108-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
FOCC004040-PC	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
FOCC003172-PA	16	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC004117-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
FOCC007416-PA	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
FOCC012516-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC016988-PA	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
FOCC006501-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
FOCC008058-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
FOCC009255-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC003849-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC007396-PA	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
FOCC005031-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
FOCC003235-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
FOCC003771-PA	8	MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
FOCC013659-PA	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
FOCC004978-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC012358-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
FOCC007977-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC015346-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
FOCC004111-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC013088-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC003650-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC011377-PA	8	KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-5394;MetaCyc: PWY-5049;MetaCyc: PWY-6133	"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Catecholamine biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis II"
FOCC001436-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
FOCC008388-PA	4	MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
FOCC016978-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC010858-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC010763-PA	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
FOCC006528-PA	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
FOCC006642-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
FOCC005754-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC008463-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
FOCC009550-PA	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC001064-PA	17	Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5358565	"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
FOCC014661-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC000894-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC016653-PA	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
FOCC002245-PA	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
FOCC004656-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC004777-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC016625-PA	9	Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162	"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape"
FOCC008298-PA	5	Reactome: R-HSA-3656237;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
FOCC003164-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC017393-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC004063-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC011106-PA	56	Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-75815	"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D"
FOCC003347-PA	5	MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism"
FOCC004446-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC007917-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
FOCC017230-PA	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
FOCC012285-PA	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
FOCC013082-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC009242-PA	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
FOCC009222-PA	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose metabolism"
FOCC012001-PA	1	MetaCyc: PWY-6938	"NADH repair"
FOCC003817-PA	12	Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4"
FOCC007075-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
FOCC004250-PA	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
FOCC001232-PA	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
FOCC006536-PA	26	Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-400253	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock"
FOCC008030-PA	5	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
FOCC001892-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
FOCC004040-PB	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
FOCC008280-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC011039-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
FOCC017008-PA	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
FOCC015286-PA	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
FOCC007390-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC006103-PA	27	Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5619107	"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
FOCC002662-PA	17	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
FOCC009125-PA	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295	"Neutrophil degranulation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation"
FOCC013024-PA	6	Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16	"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway"
FOCC008291-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
FOCC010727-PA	4	Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041	"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
FOCC014774-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
FOCC003860-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC008600-PA	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
FOCC003767-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC014435-PA	7	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids"
FOCC014877-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
FOCC000711-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
FOCC014967-PA	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
FOCC014316-PA	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
FOCC010832-PA	7	Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-381340	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation"
FOCC011672-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC015007-PA	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
FOCC017772-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC005060-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
FOCC002019-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC000269-PA	20	Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-6804756	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation"
FOCC004467-PA	10	Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-2151201	"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis"
FOCC008327-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;MetaCyc: PWY-7511;KEGG: 00480+3.4.11.1	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Glutathione metabolism"
FOCC002900-PA	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
FOCC006865-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC018036-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC012208-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
FOCC015965-PA	5	KEGG: 00550+2.5.1.7;MetaCyc: PWY-7953;MetaCyc: PWY-6386;MetaCyc: PWY-6387;KEGG: 00520+2.5.1.7	"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Amino sugar and nucleotide sugar metabolism"
FOCC008920-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
FOCC016550-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC014948-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC010970-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC003845-PA	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
FOCC015089-PA	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
FOCC004939-PA	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
FOCC003557-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC015956-PA	3	MetaCyc: PWY-6749;Reactome: R-HSA-8949664;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Processing of SMDT1";"Amino sugar and nucleotide sugar metabolism"
FOCC001903-PA	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
FOCC008461-PA	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
FOCC002035-PA	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
FOCC011537-PA	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
FOCC005289-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
FOCC000191-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
FOCC004023-PA	27	Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3108214	"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins"
FOCC004524-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
FOCC007566-PA	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis"
FOCC012618-PA	16	Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-176409	"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins"
FOCC009226-PA	13	Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5690	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)"
FOCC004248-PA	8	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
FOCC016540-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC014439-PA	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
FOCC004730-PA	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC005044-PA	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
FOCC007086-PA	40	MetaCyc: PWY-7726;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-7401;MetaCyc: PWY-5136;MetaCyc: PWY-7094;MetaCyc: PWY-7216;MetaCyc: PWY-6944;MetaCyc: PWY-7656;MetaCyc: PWY-5109;MetaCyc: PWY-6435;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-5138;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7654;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00930+4.2.1.17+1.1.1.35	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid salvage";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"Lysine degradation";"Methyl tert-butyl ether degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"2-methylpropene degradation";"Fatty acid elongation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Toluene degradation";"Pyruvate fermentation to butanol I";"Butanoate metabolism";"Phenylalanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to hexanol (engineered)";"Geraniol degradation";"Propanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Glutaryl-coa degradation";"Caprolactam degradation"
FOCC004108-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC001871-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC007056-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
FOCC006060-PA	10	Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938	"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)"
FOCC013047-PA	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
FOCC014728-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
FOCC006170-PA	10	Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122	"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Synthesis of PC";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
FOCC001847-PA	7	Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
FOCC000024-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC011516-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC013382-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
FOCC014043-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
FOCC014891-PA	4	KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;MetaCyc: PWY-5874;Reactome: R-HSA-189483	"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation I";"Heme degradation"
FOCC001040-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC000237-PA	9	MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6471;Reactome: R-HSA-5633231;MetaCyc: PWY-6470;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227;KEGG: 00513+2.4.1.141	"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"Various types of N-glycan biosynthesis"
FOCC001711-PA	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
FOCC012541-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
FOCC005042-PA	4	Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex"
FOCC015802-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
FOCC000984-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC011884-PA	26	Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320	"Kinesins";"Gap junction assembly";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes"
FOCC004603-PA	8	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
FOCC004927-PA	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
FOCC004156-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
FOCC005765-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC007136-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC000705-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC008214-PA	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
FOCC001222-PA	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
FOCC004566-PA	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC005404-PA	27	Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214	"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins"
FOCC011139-PA	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
FOCC011786-PA	12	Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;MetaCyc: PWY-6527;MetaCyc: PWY-3801;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343	"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I"
FOCC017513-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC000169-PA	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
FOCC013440-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
FOCC017968-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
FOCC016986-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC003267-PA	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
FOCC005186-PA	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
FOCC014930-PA	11	MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-6992;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-3861	"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II"
FOCC005689-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC003896-PA	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
FOCC014095-PA	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
FOCC000956-PA	6	MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004	"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I"
FOCC004404-PA	19	KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-6545;Reactome: R-HSA-380320;MetaCyc: PWY-7187;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7184;Reactome: R-HSA-380270;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6	"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
FOCC002172-PA	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
FOCC010876-PA	56	Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050	"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
FOCC013649-PA	11	KEGG: 00250+2.1.3.2;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;MetaCyc: PWY-7790	"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II"
FOCC001074-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
FOCC013213-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC015428-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC006766-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
FOCC005436-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC008578-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC005374-PA	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
FOCC014265-PA	10	MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587	"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
FOCC005243-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC002112-PA	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
FOCC005230-PA	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
FOCC008338-PA	3	Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741	"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
FOCC012156-PA	57	Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL"
FOCC009140-PA	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
FOCC005803-PA	7	KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-6614;Reactome: R-HSA-1474151;MetaCyc: PWY-3841;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3	"Folate biosynthesis";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"G1/S-Specific Transcription";"One carbon pool by folate"
FOCC011447-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC005090-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
FOCC000101-PA	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
FOCC012422-PA	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
FOCC008226-PA	41	Reactome: R-HSA-5654221;Reactome: R-HSA-2219530;Reactome: R-HSA-5654706;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-5654695;Reactome: R-HSA-5654700;Reactome: R-HSA-5654688;Reactome: R-HSA-5654712;Reactome: R-HSA-8851708;Reactome: R-HSA-5654228;Reactome: R-HSA-1257604;Reactome: R-HSA-5654687;Reactome: R-HSA-190377;Reactome: R-HSA-5655253;Reactome: R-HSA-190372;Reactome: R-HSA-6811558;Reactome: R-HSA-5654699;Reactome: R-HSA-5673001;Reactome: R-HSA-5654689;Reactome: R-HSA-5655302;Reactome: R-HSA-5654704;Reactome: R-HSA-5654227;Reactome: R-HSA-2033514;Reactome: R-HSA-8853338;Reactome: R-HSA-5654727;Reactome: R-HSA-190371;Reactome: R-HSA-2033519;Reactome: R-HSA-5654219;Reactome: R-HSA-109704;Reactome: R-HSA-190375;Reactome: R-HSA-1839122;Reactome: R-HSA-190370;Reactome: R-HSA-5654726;Reactome: R-HSA-5654719;Reactome: R-HSA-1839130;Reactome: R-HSA-190373;Reactome: R-HSA-5654693;Reactome: R-HSA-190322;Reactome: R-HSA-5654720;Reactome: R-HSA-5654710	"Phospholipase C-mediated cascade, FGFR2";"Constitutive Signaling by Aberrant PI3K in Cancer";"FRS-mediated FGFR3 signaling";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR2";"FRS-mediated FGFR2 signaling";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR4 signaling";"Signaling by FGFR2 IIIa TM";"Phospholipase C-mediated cascade, FGFR4";"PIP3 activates AKT signaling";"Downstream signaling of activated FGFR1";"FGFR2b ligand binding and activation";"Signaling by FGFR2 in disease";"FGFR3c ligand binding and activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-mediated cascade:FGFR2";"RAF/MAP kinase cascade";"PI-3K cascade:FGFR1";"Signaling by FGFR1 in disease";"SHC-mediated cascade:FGFR3";"Phospholipase C-mediated cascade, FGFR3";"FGFR3 mutant receptor activation";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR2 signaling";"FGFR3b ligand binding and activation";"Activated point mutants of FGFR2";"Phospholipase C-mediated cascade: FGFR1";"PI3K Cascade";"FGFR2c ligand binding and activation";"Signaling by activated point mutants of FGFR1";"FGFR1b ligand binding and activation";"Negative regulation of FGFR1 signaling";"SHC-mediated cascade:FGFR4";"Signaling by activated point mutants of FGFR3";"FGFR1c ligand binding and activation";"FRS-mediated FGFR1 signaling";"FGFR4 ligand binding and activation";"PI-3K cascade:FGFR4";"PI-3K cascade:FGFR3"
FOCC004548-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC008311-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
FOCC011710-PA	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
FOCC007017-PA	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
FOCC000328-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC003858-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC014421-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC004442-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
FOCC007706-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC003301-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC014508-PA	56	Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084	"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Neddylation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C"
FOCC001186-PA	4	Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6	"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate"
FOCC015942-PA	57	Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184	"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
FOCC007842-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC003667-PA	26	Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-8866907;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-933541	"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"Activation of the TFAP2 (AP-2) family of transcription factors";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation"
FOCC002287-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
FOCC004858-PA	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
FOCC003256-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC005332-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
FOCC007507-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC016619-PA	3	Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669	"Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
FOCC009021-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC013046-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC007846-PA	1	Reactome: R-HSA-5635838	"Activation of SMO"
FOCC000352-PA	5	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)"
FOCC007357-PA	7	MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms"
FOCC005225-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC001170-PA	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807	"T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling"
FOCC014051-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC001662-PA	7	Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
FOCC002713-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC012023-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
FOCC012706-PA	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events"
FOCC008611-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC009364-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC001410-PA	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
FOCC014145-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC002888-PA	4	KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
FOCC002819-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC005874-PA	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
FOCC008410-PA	16	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC000129-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
FOCC002632-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
FOCC006607-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
FOCC017100-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC002169-PA	3	Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
FOCC000420-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC011040-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
FOCC012349-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC012485-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
FOCC006114-PA	4	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC003596-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC000404-PA	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
FOCC014832-PA	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC008624-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC017006-PA	7	Reactome: R-HSA-5696395;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER"
FOCC015801-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
FOCC008954-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
FOCC007002-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
FOCC003185-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
FOCC013307-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
FOCC003970-PA	11	Reactome: R-HSA-5685938;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793	"HDR through Single Strand Annealing (SSA)";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"Myogenesis"
FOCC000727-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC005675-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC016238-PA	2	MetaCyc: PWY-8106;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
FOCC009596-PA	11	Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111457	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria"
FOCC007230-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC014418-PA	19	Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-432142;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038	"LDL remodeling";"VLDL assembly";"Chylomicron assembly";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Platelet sensitization by LDL";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"VLDL clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"LDL clearance"
FOCC003788-PA	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780	"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome"
FOCC000052-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
FOCC004763-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC012951-PA	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC009459-PA	5	MetaCyc: PWY-6580;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368	"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
FOCC006748-PA	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
FOCC008720-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC003042-PA	6	Reactome: R-HSA-2173796;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs"
FOCC001751-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC006643-PA	5	Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
FOCC002215-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC007055-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC003488-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC004237-PA	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
FOCC012768-PA	8	KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Streptomycin biosynthesis"
FOCC017016-PA	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
FOCC001905-PA	6	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
FOCC002907-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC003149-PA	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
FOCC008564-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC003045-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC009024-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC003491-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
FOCC008477-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC009543-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC004644-PA	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
FOCC007233-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC005346-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC008254-PA	18	Reactome: R-HSA-72695;Reactome: R-HSA-166208;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Formation of the ternary complex, and subsequently, the 43S complex";"mTORC1-mediated signalling";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
FOCC007047-PA	4	Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)"
FOCC006695-PA	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
FOCC012227-PA	5	KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)"
FOCC009305-PA	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
FOCC011739-PA	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
FOCC013089-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC015832-PA	6	KEGG: 00720+4.2.1.3;MetaCyc: PWY-5747;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00640+4.2.1.99;KEGG: 00020+4.2.1.3	"Carbon fixation pathways in prokaryotes";"2-methylcitrate cycle II";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Propanoate metabolism";"Citrate cycle (TCA cycle)"
FOCC001261-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC017770-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC005520-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
FOCC002890-PA	7	Reactome: R-HSA-4549349;Reactome: R-HSA-5389840;Reactome: R-HSA-446193;Reactome: R-HSA-5368286;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-5419276	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Mitochondrial translation elongation";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Mitochondrial translation initiation";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Mitochondrial translation termination"
FOCC013664-PA	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
FOCC013108-PA	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
FOCC016612-PA	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
FOCC007506-PA	12	Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-2132295	"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation"
FOCC012559-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
FOCC011250-PA	24	Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-6814122	"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G-protein activation";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
FOCC005662-PA	18	MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7197	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation"
FOCC015065-PA	6	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state"
FOCC006026-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC007728-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC007831-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
FOCC008823-PA	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
FOCC015958-PA	2	Reactome: R-HSA-75105;Reactome: R-HSA-389661	"Fatty acyl-CoA biosynthesis";"Glyoxylate metabolism and glycine degradation"
FOCC006819-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC008407-PA	6	MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
FOCC011502-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC017254-PA	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones"
FOCC014833-PA	4	KEGG: 00010+3.1.3.9;KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Gluconeogenesis"
FOCC007793-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC003580-PA	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
FOCC004622-PA	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
FOCC008773-PA	4	Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138	"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
FOCC015873-PA	4	KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;MetaCyc: PWY-6922	"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis"
FOCC000702-PA	6	Reactome: R-HSA-174437;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-5651801	"Removal of the Flap Intermediate from the C-strand";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair"
FOCC002292-PA	14	MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Arachidonic acid metabolism"
FOCC013119-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC003937-PA	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
FOCC001495-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC015524-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC009096-PA	13	Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC007219-PA	10	MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061	"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I"
FOCC008099-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
FOCC008810-PA	8	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Neutrophil degranulation";"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK"
FOCC006734-PA	4	Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-6809583	"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Retinoid metabolism disease events"
FOCC011118-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC011379-PA	4	Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-156581	"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Methylation"
FOCC001248-PA	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
FOCC007615-PA	1	Reactome: R-HSA-525793	"Myogenesis"
FOCC009233-PA	10	MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-6613;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201	"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I"
FOCC005240-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
FOCC005074-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
FOCC012872-PA	9	Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237	"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2"
FOCC005213-PA	2	KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19	"Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism"
FOCC013187-PA	1	Reactome: R-HSA-74217	"Purine salvage"
FOCC009548-PA	18	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;KEGG: 00970+6.1.1.1;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-379726;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Aminoacyl-tRNA biosynthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Mitochondrial tRNA aminoacylation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation"
FOCC011561-PA	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
FOCC007401-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC007961-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC015071-PA	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
FOCC003757-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC001303-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC008819-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC003515-PA	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
FOCC002548-PA	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
FOCC005088-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
FOCC014786-PA	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
FOCC001244-PA	6	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"Mitochondrial protein import";"Cristae formation";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Oxidative phosphorylation"
FOCC002345-PA	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
FOCC005910-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC011419-PB	6	KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530	"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II"
FOCC004216-PA	9	MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-241	"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
FOCC001732-PA	14	Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
FOCC005210-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC012759-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC012039-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC012821-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC005247-PA	56	Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-5610783	"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"UCH proteinases";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"G2/M Checkpoints";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome"
FOCC013055-PA	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
FOCC017895-PA	7	MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469	"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis"
FOCC015136-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC003462-PA	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
FOCC016188-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC013336-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
FOCC011684-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC016331-PA	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
FOCC016640-PA	9	MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5664	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II"
FOCC001158-PA	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7725	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
FOCC009318-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC016666-PA	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
FOCC012211-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC012926-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
FOCC005635-PA	27	Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3301854	"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly"
FOCC005637-PA	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
FOCC010737-PA	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
FOCC007974-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC017904-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC014342-PA	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
FOCC002780-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC008261-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC012305-PA	1	Reactome: R-HSA-186797	"Signaling by PDGF"
FOCC008629-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC016161-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC007293-PA	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
FOCC003729-PA	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
FOCC009111-PA	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
FOCC017748-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
FOCC015450-PA	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
FOCC015364-PA	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
FOCC004290-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC008576-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
FOCC000443-PA	4	Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation"
FOCC004186-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
FOCC015878-PA	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
FOCC009311-PA	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
FOCC008990-PA	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
FOCC015335-PA	3	KEGG: 00020+1.1.5.4;KEGG: 00620+1.1.5.4;MetaCyc: PWY-7254	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)"
FOCC015448-PA	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization"
FOCC008303-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC016214-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
FOCC015766-PA	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
FOCC016266-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
FOCC013637-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-901032	"Protein ubiquitination";"ER Quality Control Compartment (ERQC)"
FOCC014325-PA	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"CS/DS degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)"
FOCC007095-PA	7	Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12	"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
FOCC002211-PA	6	Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565	"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
FOCC003334-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC005959-PA	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
FOCC000082-PA	7	Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;MetaCyc: PWY-6605;MetaCyc: PWY-7807;MetaCyc: PWY-7805;MetaCyc: PWY-6610	"Neutrophil degranulation";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage II";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Adenine salvage"
FOCC008979-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC001162-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC000158-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
FOCC000116-PA	16	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC002004-PA	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
FOCC017117-PA	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
FOCC006067-PA	33	Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107	"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
FOCC004669-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC000095-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC000650-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC010815-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
FOCC014045-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
FOCC013337-PA	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
FOCC008540-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC005928-PA	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
FOCC003887-PA	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
FOCC008073-PA	11	MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-5668599;Reactome: R-HSA-1660517;Reactome: R-HSA-109704;Reactome: R-HSA-168138;Reactome: R-HSA-1632852	"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the late endosome membrane";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"Macroautophagy"
FOCC002669-PA	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
FOCC013797-PA	7	Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
FOCC008007-PA	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
FOCC005172-PA	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC012141-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
FOCC003220-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
FOCC009531-PA	17	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
FOCC013761-PA	15	Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-2173796;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-176034;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238	"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
FOCC013268-PA	1	Reactome: R-HSA-189451	"Heme biosynthesis"
FOCC006936-PA	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
FOCC014414-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
FOCC016717-PA	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
FOCC004429-PA	4	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis"
FOCC008012-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC003292-PA	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
FOCC008900-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC015976-PA	11	KEGG: 00230+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9	"Purine metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism"
FOCC013451-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC014770-PA	12	Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167243	"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery"
FOCC003626-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC004344-PA	11	Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972	"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK"
FOCC011095-PA	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
FOCC015694-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC008389-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
FOCC003482-PA	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
FOCC004875-PA	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
FOCC017808-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
FOCC011866-PA	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
FOCC001758-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC016733-PA	6	MetaCyc: PWY-7383;Reactome: R-HSA-74259;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;KEGG: 00230+3.6.1.66;MetaCyc: PWY-8040	"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine catabolism";"D-Alanine metabolism";"Alanine racemization";"Purine metabolism";"Ansatrienin biosynthesis"
FOCC009126-PA	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695	"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Neutrophil degranulation"
FOCC008464-PA	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
FOCC002467-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC013675-PA	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
FOCC011838-PA	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
FOCC007606-PA	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
FOCC008061-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC000496-PA	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
FOCC005599-PA	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
FOCC009394-PA	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
FOCC001388-PA	4	Reactome: R-HSA-6798695;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"Neutrophil degranulation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC012798-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
FOCC012215-PA	7	Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
FOCC017334-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
FOCC016680-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
FOCC002586-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC012865-PA	5	Reactome: R-HSA-983168;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-977225	"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs";"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation"
FOCC002927-PA	3	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway"
FOCC017950-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC008259-PA	44	Reactome: R-HSA-375165;Reactome: R-HSA-170968;Reactome: R-HSA-450341;Reactome: R-HSA-445144;Reactome: R-HSA-879415;Reactome: R-HSA-8939211;Reactome: R-HSA-74749;Reactome: R-HSA-6802946;Reactome: R-HSA-5654726;Reactome: R-HSA-9649948;Reactome: R-HSA-2029482;Reactome: R-HSA-198753;Reactome: R-HSA-8940973;Reactome: R-HSA-5675221;Reactome: R-HSA-162658;Reactome: R-HSA-5654727;Reactome: R-HSA-1295596;Reactome: R-HSA-2559585;Reactome: R-HSA-202670;Reactome: R-HSA-9634638;Reactome: R-HSA-456926;Reactome: R-HSA-6802948;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-5663213;Reactome: R-HSA-5674499;Reactome: R-HSA-6802955;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-5668599;Reactome: R-HSA-9635465;Reactome: R-HSA-2871796;Reactome: R-HSA-982772;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654732;Reactome: R-HSA-112409;Reactome: R-HSA-2559582;Reactome: R-HSA-6802952;Reactome: R-HSA-881907;Reactome: R-HSA-5654733;Reactome: R-HSA-3371453;Reactome: R-HSA-9627069;Reactome: R-HSA-5674135;Reactome: R-HSA-444257	"NCAM signaling for neurite out-growth";"Frs2-mediated activation";"Activation of the AP-1 family of transcription factors";"Signal transduction by L1";"Advanced glycosylation endproduct receptor signaling";"ESR-mediated signaling";"Signal attenuation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR1 signaling";"Signaling downstream of RAS mutants";"Regulation of actin dynamics for phagocytic cup formation";"ERK/MAPK targets";"RUNX2 regulates osteoblast differentiation";"Negative regulation of MAPK pathway";"Golgi Cisternae Pericentriolar Stack Reorganization";"Negative regulation of FGFR2 signaling";"Spry regulation of FGF signaling";"Oncogene Induced Senescence";"ERKs are inactivated";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling by high-kinase activity BRAF mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"RHO GTPases Activate WASPs and WAVEs";"Negative feedback regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RHO GTPases Activate NADPH Oxidases";"Suppression of apoptosis";"FCERI mediated MAPK activation";"Growth hormone receptor signaling";"mTOR signaling pathway";"Negative regulation of FGFR3 signaling";"RAF-independent MAPK1/3 activation";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling by BRAF and RAF fusions";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative regulation of FGFR4 signaling";"Regulation of HSF1-mediated heat shock response";"Regulation of the apoptosome activity";"MAP2K and MAPK activation";"RSK activation"
FOCC017558-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC012833-PA	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
FOCC002566-PA	5	Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins"
FOCC011270-PA	10	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
FOCC011321-PA	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
FOCC015875-PA	5	MetaCyc: PWY-1269;KEGG: 00400+2.5.1.54;MetaCyc: PWY-6164;MetaCyc: PWY-7674;KEGG: 00540+2.5.1.55	"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"3-dehydroquinate biosynthesis I";"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis"
FOCC002174-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC011117-PA	30	Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-1170546;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-2644606;Reactome: R-HSA-917937;Reactome: R-HSA-195253;Reactome: R-HSA-400253;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-2565942;Reactome: R-HSA-8939902	"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Prolactin receptor signaling";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Interleukin-1 signaling";"Neddylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Iron uptake and transport";"Degradation of beta-catenin by the destruction complex";"Circadian Clock";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of RUNX2 expression and activity"
FOCC016446-PA	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
FOCC005073-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC011558-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
FOCC011188-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
FOCC017429-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC000861-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC011503-PA	5	MetaCyc: PWY-6012;MetaCyc: PWY-6289;MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7;Reactome: R-HSA-199220	"Acyl carrier protein metabolism";"Petrobactin biosynthesis";"Acyl carrier protein activation";"Pantothenate and CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism"
FOCC011200-PA	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
FOCC014099-PA	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis"
FOCC011364-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC009120-PA	4	KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
FOCC011922-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC015372-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC006967-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
FOCC004008-PA	3	Reactome: R-HSA-5656169;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Termination of translesion DNA synthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC001971-PA	15	Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-196299	"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Beta-catenin phosphorylation cascade"
FOCC016782-PA	13	MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7709;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7659	"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"(3R)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis"
FOCC003728-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
FOCC009436-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC008452-PA	4	MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
FOCC014163-PA	1	Reactome: R-HSA-5334118	"DNA methylation"
FOCC002470-PA	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
FOCC014488-PA	1	MetaCyc: PWY-7883	"Anhydromuropeptides recycling II"
FOCC003809-PA	26	Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-8941856;Reactome: R-HSA-3371568;Reactome: R-HSA-201722	"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RUNX3 regulates NOTCH signaling";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex"
FOCC015705-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-6784531	"Mitochondrial protein import";"tRNA processing in the nucleus"
FOCC010705-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC013099-PA	4	MetaCyc: PWY-7286;Reactome: R-HSA-6782861;MetaCyc: PWY-7285;MetaCyc: PWY-6829	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis";"Trna methylation (yeast)"
FOCC017524-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
FOCC011464-PA	6	Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;MetaCyc: PWY-7920	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)"
FOCC005507-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC006030-PA	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
FOCC010808-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
FOCC003276-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC000294-PA	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
FOCC014516-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC006699-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC014694-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC004537-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
FOCC012747-PA	3	Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation"
FOCC017765-PA	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
FOCC006949-PA	57	Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870	"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Neddylation";"Interleukin-1 signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"G2/M Checkpoints";"Ub-specific processing proteases";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins"
FOCC012390-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC001552-PA	14	Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5655862	"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLK"
FOCC007024-PA	52	Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-8851708;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-167158;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73762	"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation"
FOCC005421-PA	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
FOCC002731-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
FOCC003327-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC005766-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC003617-PA	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
FOCC007581-PA	2	Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
FOCC008893-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC002006-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC009535-PA	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
FOCC002694-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC013746-PA	6	Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642	"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
FOCC009130-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC015972-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC013428-PA	7	MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7214	"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
FOCC009604-PB	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
FOCC008487-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC005417-PA	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
FOCC008547-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC009532-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
FOCC004298-PA	15	Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation"
FOCC000248-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC001698-PA	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
FOCC004989-PA	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins"
FOCC003251-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC012433-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC002768-PA	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
FOCC006344-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC000726-PA	56	Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-180534	"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4"
FOCC004753-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC001188-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC014897-PA	13	MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7721	"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis"
FOCC003074-PA	18	KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5690;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-7115;MetaCyc: PWY-5913	"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Reductive TCA cycle II";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)"
FOCC003324-PA	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
FOCC005602-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC015033-PA	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
FOCC013042-PA	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
FOCC014759-PA	2	MetaCyc: PWY-6164;KEGG: 00400+4.2.3.4	"3-dehydroquinate biosynthesis I";"Phenylalanine, tyrosine and tryptophan biosynthesis"
FOCC012236-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC012855-PA	27	Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-1169408	"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism"
FOCC016208-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
FOCC006823-PA	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
FOCC006327-PA	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
FOCC004990-PA	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC008111-PA	3	Reactome: R-HSA-3065678;Reactome: R-HSA-983168;Reactome: R-HSA-3065676	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)"
FOCC002176-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
FOCC016524-PA	5	MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;Reactome: R-HSA-73817	"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
FOCC009396-PA	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
FOCC005415-PA	8	Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Signaling by Hippo";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
FOCC003337-PA	1	Reactome: R-HSA-264876	"Insulin processing"
FOCC017493-PA	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
FOCC007799-PA	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis"
FOCC012769-PA	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
FOCC007104-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC015479-PA	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
FOCC016663-PA	9	Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
FOCC001625-PA	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
FOCC012073-PA	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway"
FOCC001672-PA	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-174430	"DNA replication initiation";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Telomere C-strand synthesis initiation"
FOCC012013-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
FOCC016180-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
FOCC005718-PA	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
FOCC000396-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC000475-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
FOCC003597-PA	29	Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-6781823	"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex"
FOCC005913-PA	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340	"EML4 and NUDC in mitotic spindle formation";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation";"AXIN missense mutants destabilize the destruction complex"
FOCC007806-PA	4	Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
FOCC015824-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC000758-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC009032-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
FOCC007808-PA	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
FOCC004890-PA	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
FOCC004718-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC003808-PA	8	Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
FOCC006312-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
FOCC007969-PA	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
FOCC012323-PA	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
FOCC011239-PA	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
FOCC013666-PA	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5362798	"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell"
FOCC011043-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC001397-PA	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
FOCC012902-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC005571-PA	4	Reactome: R-HSA-72086;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE"
FOCC006711-PA	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
FOCC016734-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC016714-PA	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
FOCC014872-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC016697-PA	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
FOCC000412-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC000627-PA	10	MetaCyc: PWY-7187;MetaCyc: PWY-3841;MetaCyc: PWY-7198;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7199;Reactome: R-HSA-69205;Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"One carbon pool by folate";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
FOCC007583-PA	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
FOCC012295-PA	3	KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685	"Pyrimidine metabolism";"Purine metabolism";"Detoxification of Reactive Oxygen Species"
FOCC008294-PA	1	Reactome: R-HSA-1483255	"PI Metabolism"
FOCC005649-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC000042-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
FOCC005794-PA	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
FOCC017921-PA	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
FOCC013973-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
FOCC009174-PA	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
FOCC004138-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC003304-PA	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
FOCC008771-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
FOCC017116-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC009449-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC017771-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC005915-PB	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC006939-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC001456-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
FOCC004529-PA	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
FOCC015031-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
FOCC004488-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC001424-PA	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
FOCC011852-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
FOCC011299-PA	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
FOCC011184-PA	3	MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-532668	"Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
FOCC009461-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC008014-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
FOCC006366-PA	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC001823-PA	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
FOCC009030-PA	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway"
FOCC006247-PA	3	Reactome: R-HSA-881907;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
FOCC003125-PA	8	MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-1989781	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression"
FOCC014744-PA	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
FOCC003513-PA	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
FOCC008966-PA	5	KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-193048;Reactome: R-HSA-446199;MetaCyc: PWY-6129	"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis"
FOCC017582-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC001774-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
FOCC006557-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC016765-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC007277-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC003717-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
FOCC015681-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
FOCC001218-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC011197-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
FOCC015672-PA	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
FOCC002620-PA	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
FOCC017857-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC003622-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
FOCC009219-PA	4	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
FOCC009527-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
FOCC011730-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC002250-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC014127-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC014213-PA	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
FOCC014005-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC002516-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
FOCC017398-PA	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC012055-PA	6	Reactome: R-HSA-196780;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
FOCC011017-PA	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
FOCC015896-PA	7	Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
FOCC006042-PA	4	Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA"
FOCC015052-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC007680-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC001668-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC005750-PA	4	Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
FOCC001432-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC010826-PA	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC013878-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC003671-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC017121-PA	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
FOCC013222-PA	10	KEGG: 05165+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-1660499	"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection";"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane"
FOCC012308-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC015898-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC012406-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC005819-PA	7	Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7836;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80	"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism"
FOCC012157-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC002040-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC003016-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
FOCC002057-PA	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
FOCC014740-PA	3	Reactome: R-HSA-5362517;Reactome: R-HSA-70895;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
FOCC005660-PA	8	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-9639288	"Ion channel transport";"Insulin receptor recycling";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1"
FOCC006171-PA	4	Reactome: R-HSA-975957;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
FOCC016114-PA	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
FOCC000369-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
FOCC006686-PA	22	KEGG: 00062+4.2.1.134;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-7727;MetaCyc: PWY-7601;MetaCyc: PWY-7053;MetaCyc: PWY-5080;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6958;MetaCyc: PWY-5353;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
FOCC000830-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
FOCC011293-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC005995-PA	11	Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-68952	"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation"
FOCC005966-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC000110-PA	34	Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-9639288;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-5663220;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-159230	"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"Amino acids regulate mTORC1";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"RHO GTPases Activate Formins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA"
FOCC017574-PA	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
FOCC007010-PA	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
FOCC001129-PA	11	MetaCyc: PWY-7185;MetaCyc: PWY-5381;MetaCyc: PWY-6608;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-7821;MetaCyc: PWY-6596;MetaCyc: PWY-6606	"UTP and CTP dephosphorylation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Tunicamycin biosynthesis";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II"
FOCC008102-PA	10	Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-983168	"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC001259-PA	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC015499-PA	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
FOCC012989-PA	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
FOCC006890-PA	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
FOCC001375-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
FOCC016358-PA	4	Reactome: R-HSA-8849175;MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
FOCC015702-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC012172-PA	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
FOCC013111-PA	57	Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091	"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells"
FOCC001873-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
FOCC011676-PA	6	Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER"
FOCC006889-PA	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
FOCC008932-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC000548-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC002919-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC015055-PA	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
FOCC004888-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC001629-PA	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
FOCC002605-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC011431-PA	17	Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176408	"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase"
FOCC014310-PA	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
FOCC011781-PA	5	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events"
FOCC008113-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
FOCC010768-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC015327-PA	16	Reactome: R-HSA-5368286;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-5419276;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-5389840;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Mitochondrial translation initiation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Mitochondrial translation termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Mitochondrial translation elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
FOCC004383-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
FOCC001483-PA	11	MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055;MetaCyc: PWY-7782;Reactome: R-HSA-2029485;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053	"Anandamide biosynthesis I";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Role of phospholipids in phagocytosis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
FOCC017861-PA	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
FOCC007192-PA	6	Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism"
FOCC003696-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC003140-PA	24	Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295	"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Gap junction assembly";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Cilium Assembly";"MHC class II antigen presentation"
FOCC006962-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC014571-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC000283-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC013800-PA	5	Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
FOCC009227-PA	14	KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-4302;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1	"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism"
FOCC014852-PA	5	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Glycine, serine and threonine metabolism"
FOCC000287-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC005853-PA	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
FOCC012353-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
FOCC007239-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC013264-PA	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
FOCC002140-PA	12	MetaCyc: PWY-6683;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25	"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Sulfite oxidation III";"Selenocompound metabolism";"Purine metabolism";"Sulfur metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfur metabolism";"Purine metabolism"
FOCC005313-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
FOCC002864-PA	1	Reactome: R-HSA-419771	"Opsins"
FOCC000147-PA	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
FOCC006007-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
FOCC000096-PA	26	Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-9018519;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-8866907;Reactome: R-HSA-201722;Reactome: R-HSA-3371568	"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"Estrogen-dependent gene expression";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase"
FOCC002891-PA	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Human papillomavirus infection"
FOCC015637-PA	33	Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885	"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins"
FOCC003540-PA	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
FOCC003118-PA	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
FOCC014198-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC016655-PA	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
FOCC002344-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
FOCC000092-PA	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
FOCC003724-PA	5	Reactome: R-HSA-5545619;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
FOCC013810-PA	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC011682-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC007911-PA	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
FOCC004510-PA	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC013584-PA	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
FOCC008017-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
FOCC001710-PA	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
FOCC014518-PA	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7725	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)"
FOCC003465-PA	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
FOCC000530-PA	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
FOCC001950-PA	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
FOCC002700-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC010772-PA	16	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC002407-PA	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
FOCC002421-PA	7	MetaCyc: PWY-3561;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4	"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PA";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Ether lipid metabolism"
FOCC004466-PA	5	Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
FOCC016310-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC002995-PA	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
FOCC003466-PA	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
FOCC017972-PA	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
FOCC004974-PA	19	Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663220;Reactome: R-HSA-194840;Reactome: R-HSA-5625970;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-5663213;Reactome: R-HSA-8964616;Reactome: R-HSA-5626467;Reactome: R-HSA-389359;Reactome: R-HSA-428543	"Myogenesis";"DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"MAPK6/MAPK4 signaling";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate Formins";"Rho GTPase cycle";"RHO GTPases activate KTN1";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate WASPs and WAVEs";"G beta:gamma signalling through CDC42";"RHO GTPases activate IQGAPs";"CD28 dependent Vav1 pathway";"Inactivation of CDC42 and RAC1"
FOCC005719-PA	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
FOCC002480-PA	9	KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-112043	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events"
FOCC011223-PB	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
FOCC014290-PA	4	Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
FOCC012511-PA	33	Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-2500257	"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion"
FOCC017532-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
FOCC012354-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
FOCC015938-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC016709-PA	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
FOCC010865-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
FOCC017906-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC006135-PA	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
FOCC007283-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC009478-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
FOCC016031-PA	6	Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
FOCC007409-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC017367-PA	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones"
FOCC004873-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
FOCC009100-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
FOCC007622-PA	20	Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165159;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;KEGG: 05165+2.7.11.1	"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"HSF1-dependent transactivation";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"mTOR signalling";"PI3K-Akt signaling pathway";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Human papillomavirus infection"
FOCC007563-PA	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
FOCC008978-PA	16	Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-176412	"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C"
FOCC000974-PA	10	MetaCyc: PWY-6366;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231;MetaCyc: PWY-6554;MetaCyc: PWY-6365;Reactome: R-HSA-1855204	"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol"
FOCC004960-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC011716-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC002457-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC007269-PA	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
FOCC006938-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
FOCC012619-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC013551-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC016337-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC003804-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
FOCC002050-PA	12	MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5873	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)"
FOCC003135-PA	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
FOCC011991-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC012510-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
FOCC006560-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC001613-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC011082-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC011124-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC000493-PD	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
FOCC006372-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC016037-PA	9	Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC014799-PA	9	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-2426168	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"snRNP Assembly";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)"
FOCC010898-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
FOCC010717-PA	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
FOCC013016-PA	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
FOCC011767-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC003954-PA	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
FOCC002534-PA	6	KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
FOCC012796-PA	4	Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
FOCC017986-PA	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
FOCC013747-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC011275-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC012099-PA	29	Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-5696395	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER"
FOCC009480-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC004340-PA	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
FOCC012611-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC009597-PA	24	KEGG: 05163+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-392451;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;Reactome: R-HSA-202424;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-9634635;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"GPVI-mediated activation cascade";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Degradation";"RSK activation";"Downstream TCR signaling";"Relaxin signaling pathway";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Activation of AKT2";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"Integrin signaling";"Human papillomavirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Estrogen-stimulated signaling through PRKCZ";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway"
FOCC009312-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
FOCC007445-PA	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8051	"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I"
FOCC012307-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC001653-PA	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
FOCC006369-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC004616-PA	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC016924-PA	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
FOCC011302-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC014470-PA	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
FOCC002417-PA	18	MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00350+2.6.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"Sulfolactate degradation III";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Tyrosine metabolism"
FOCC017285-PA	5	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
FOCC000371-PA	10	MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-5826	"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis"
FOCC009425-PA	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
FOCC017665-PA	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
FOCC012061-PA	6	MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
FOCC015478-PA	5	Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
FOCC012597-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
FOCC002045-PA	1	Reactome: R-HSA-71288	"Creatine metabolism"
FOCC008209-PA	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
FOCC012640-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC006636-PA	5	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
FOCC004346-PA	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
FOCC014993-PA	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
FOCC003218-PA	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
FOCC015834-PA	12	KEGG: 00730+2.2.1.7;KEGG: 00020+2.3.1.12;MetaCyc: PWY-6891;KEGG: 00010+1.2.4.1;MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661	"Thiamine metabolism";"Citrate cycle (TCA cycle)";"Thiazole biosynthesis II (aerobic bacteria)";"Glycolysis / Gluconeogenesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation"
FOCC013209-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC015774-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
FOCC017381-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
FOCC000791-PA	3	Reactome: R-HSA-204005;Reactome: R-HSA-948021;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER"
FOCC003077-PA	26	Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Gap junction assembly";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
FOCC008627-PA	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
FOCC007619-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC014398-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
FOCC008975-PA	5	Reactome: R-HSA-110357;Reactome: R-HSA-9608290;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-9608287	"Displacement of DNA glycosylase by APEX1";"Defective MUTYH substrate processing";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate binding"
FOCC009224-PA	5	KEGG: 00540+2.5.1.55;MetaCyc: PWY-7674;MetaCyc: PWY-6164;KEGG: 00400+2.5.1.54;MetaCyc: PWY-1269	"Lipopolysaccharide biosynthesis";"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"3-dehydroquinate biosynthesis I";"Phenylalanine, tyrosine and tryptophan biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
FOCC016090-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
FOCC003141-PA	27	Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159231	"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
FOCC011292-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC004364-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
FOCC015797-PA	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation"
FOCC016089-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC007882-PA	5	Reactome: R-HSA-5685939;Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397	"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
FOCC008863-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
FOCC008009-PA	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
FOCC002774-PA	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
FOCC000401-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC014408-PA	10	KEGG: 05165+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5689880	"Human papillomavirus infection";"HATs acetylate histones";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"Ub-specific processing proteases"
FOCC005951-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
FOCC010758-PA	5	Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex"
FOCC001489-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
FOCC001095-PA	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
FOCC016811-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC008405-PA	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
FOCC006503-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC012424-PA	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685	"Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species"
FOCC012095-PA	4	Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
FOCC001414-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
FOCC008580-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC014880-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC009264-PA	5	Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7185	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I"
FOCC007540-PA	19	Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-975634	"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"LDL remodeling";"VLDL assembly";"Chylomicron assembly";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Post-translational protein phosphorylation";"VLDL clearance";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"LDL clearance";"Retinoid metabolism and transport"
FOCC005022-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
FOCC003093-PA	5	Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-5358346	"XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis"
FOCC004731-PA	14	Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1	"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)"
FOCC003619-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
FOCC000604-PA	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
FOCC018024-PA	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
FOCC003175-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
FOCC001854-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC015146-PA	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
FOCC015124-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC007026-PA	4	Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism"
FOCC011527-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
FOCC015347-PA	3	MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2	"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis"
FOCC002138-PA	10	KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11	"Methane metabolism";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Fructose and mannose metabolism";"Pentose phosphate pathway"
FOCC000524-PA	5	KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-7536	"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
FOCC006027-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC017115-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
FOCC008005-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC016606-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC006426-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC015730-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC001621-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC001531-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC014860-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC010798-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC007751-PA	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
FOCC006006-PA	11	MetaCyc: PWY-6549;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.42	"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes"
FOCC013271-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC000991-PA	10	MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8051	"Anandamide biosynthesis II";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I"
FOCC008491-PA	6	Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis"
FOCC004713-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC003545-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC013575-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
FOCC010943-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC006964-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC017664-PA	4	MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062	"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol"
FOCC006239-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
FOCC005345-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC017942-PA	6	MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
FOCC003260-PA	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
FOCC015949-PA	6	MetaCyc: PWY-4981;MetaCyc: PWY-7400;Reactome: R-HSA-1268020;MetaCyc: PWY-4984;Reactome: R-HSA-70635;KEGG: 00220+2.1.3.3	"L-proline biosynthesis II (from arginine)";"L-arginine biosynthesis IV (archaebacteria)";"Mitochondrial protein import";"Urea cycle";"Urea cycle";"Arginine biosynthesis"
FOCC016682-PA	5	KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes"
FOCC011646-PA	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
FOCC001867-PA	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
FOCC010824-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC014720-PA	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
FOCC009306-PA	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
FOCC010869-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC008948-PA	4	MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism"
FOCC011407-PA	4	KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27	"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
FOCC003044-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC005238-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC005787-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC006358-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
FOCC009128-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC014392-PA	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC014862-PA	3	Reactome: R-HSA-3371453;MetaCyc: PWY-7560;KEGG: 00900+1.17.7.4	"Regulation of HSF1-mediated heat shock response";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis"
FOCC000108-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC014733-PA	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
FOCC001273-PA	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
FOCC009124-PA	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation"
FOCC017249-PA	6	MetaCyc: PWY-6470;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.129;MetaCyc: PWY-6471;MetaCyc: PWY-6385;KEGG: 00550+2.4.1.129+3.4.16.4	"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis"
FOCC015612-PA	6	MetaCyc: PWY-8047;KEGG: 00061+2.3.1.39;MetaCyc: PWY-4381;MetaCyc: PWY-8012;MetaCyc: PWY-6799;MetaCyc: PWY-8049	"Bryostatin biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Pederin biosynthesis"
FOCC003454-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
FOCC011044-PA	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
FOCC009362-PA	1	Reactome: R-HSA-203615	"eNOS activation"
FOCC006310-PA	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC004802-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
FOCC001155-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC000935-PA	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
FOCC009237-PA	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
FOCC013676-PA	14	Reactome: R-HSA-71403;Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690	"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)"
FOCC014293-PA	13	Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-186797	"Laminin interactions";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"Signaling by PDGF"
FOCC007384-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC003862-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
FOCC009114-PA	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
FOCC002872-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC015132-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC011477-PA	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
FOCC014327-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC000156-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC003649-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC008683-PA	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
FOCC005429-PA	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
FOCC012237-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC010961-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
FOCC006157-PA	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
FOCC013855-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC017456-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC004229-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC013675-PB	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
FOCC014406-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
FOCC004359-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC002242-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC006818-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
FOCC006111-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC008523-PA	58	Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-5689901;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"UCH proteinases";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Metalloprotease DUBs";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN"
FOCC012315-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC013576-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
FOCC017221-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC009247-PA	3	Reactome: R-HSA-611105;Reactome: R-HSA-5628897;MetaCyc: PWY-7544	"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Pyruvate to cytochrome bo oxidase electron transfer"
FOCC003474-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC011769-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC006286-PA	17	Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-1834949;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-3270619;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Cytosolic sensors of pathogen-associated DNA";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"IRF3-mediated induction of type I IFN";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation"
FOCC014710-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC017797-PA	9	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68827	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex"
FOCC006945-PA	8	Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-983231	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production"
FOCC014991-PA	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
FOCC000651-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC011837-PA	12	Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-205043	"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"NRIF signals cell death from the nucleus"
FOCC004837-PA	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
FOCC012024-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
FOCC007985-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC013677-PA	16	Reactome: R-HSA-5603041;Reactome: R-HSA-5602680;Reactome: R-HSA-975155;Reactome: R-HSA-975138;Reactome: R-HSA-975110;Reactome: R-HSA-6811558;Reactome: R-HSA-166058;Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-5602498;Reactome: R-HSA-975871;Reactome: R-HSA-3134963;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-1257604;Reactome: R-HSA-209543	"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR5)";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"Interleukin-1 signaling";"ER-Phagosome pathway";"PIP3 activates AKT signaling";"p75NTR recruits signalling complexes"
FOCC011731-PA	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
FOCC002796-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC016230-PA	4	MetaCyc: PWY-4361;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
FOCC012623-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC001523-PA	5	Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37	"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism"
FOCC016856-PA	1	Reactome: R-HSA-70921	"Histidine catabolism"
FOCC011221-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC017427-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
FOCC015366-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC001550-PA	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
FOCC006106-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC002862-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC012999-PA	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
FOCC002233-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
FOCC005713-PA	5	KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification"
FOCC012168-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
FOCC013038-PA	4	Reactome: R-HSA-446388;Reactome: R-HSA-3000170;Reactome: R-HSA-114608;Reactome: R-HSA-373753	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"Syndecan interactions";"Platelet degranulation";"Nephrin family interactions"
FOCC006250-PA	13	KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation"
FOCC017623-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC002399-PA	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
FOCC012166-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC002562-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
FOCC000557-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC005764-PA	12	KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;MetaCyc: PWY-6527;MetaCyc: PWY-7238;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9	"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Sucrose biosynthesis II";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism"
FOCC012881-PA	18	MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7187	"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
FOCC006432-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC001042-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC012705-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
FOCC015521-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC011048-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC012036-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC008584-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC002210-PA	7	MetaCyc: PWY-7185;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545	"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
FOCC008100-PA	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC012017-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC002961-PA	5	Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
FOCC017097-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC000055-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
FOCC008630-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC006940-PA	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
FOCC009159-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
FOCC007439-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
FOCC016526-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
FOCC017686-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC013645-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC006838-PA	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
FOCC008656-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC011263-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
FOCC017566-PA	14	MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs"
FOCC001258-PA	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
FOCC000158-PB	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
FOCC008705-PA	1	Reactome: R-HSA-193670	"p75NTR negatively regulates cell cycle via SC1"
FOCC000087-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC010775-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
FOCC015741-PA	13	MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1	"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis"
FOCC013126-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
FOCC005532-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC009171-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC004349-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
FOCC001262-PA	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
FOCC004153-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
FOCC005134-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
FOCC013281-PA	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
FOCC007510-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
FOCC016934-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC008435-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC006153-PA	6	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events"
FOCC007984-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
FOCC006709-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
FOCC006716-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
FOCC003342-PA	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
FOCC003315-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC009058-PA	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
FOCC000493-PA	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
FOCC013019-PA	9	MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-241	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
FOCC014634-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC005706-PA	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
FOCC015049-PA	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
FOCC009578-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC003091-PA	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC017103-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
FOCC001307-PA	18	Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167287	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery"
FOCC000493-PC	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
FOCC006504-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
FOCC005982-PA	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway"
FOCC007545-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
FOCC009505-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC013001-PA	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
FOCC001499-PA	6	Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC007943-PA	14	MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7035	"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis"
FOCC003939-PA	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
FOCC007247-PA	13	Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC015680-PA	11	MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7560;MetaCyc: PWY-6174;MetaCyc: PWY-5123;MetaCyc: PWY-7391;MetaCyc: PWY-6859;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7524;Reactome: R-HSA-191273	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"All-trans-farnesol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis"
FOCC003692-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC016580-PA	5	Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
FOCC002778-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC008045-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC013999-PA	5	KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
FOCC011403-PA	11	Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378	"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"PKA activation in glucagon signalling"
FOCC007738-PA	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
FOCC003861-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC008579-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC008761-PA	5	MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-5269	"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Synthesis of PG";"Cardiolipin biosynthesis II"
FOCC001775-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
FOCC000992-PA	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
FOCC000109-PA	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
FOCC009285-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC016515-PA	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
FOCC016215-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC002827-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
FOCC014019-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC000853-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC008440-PA	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
FOCC011310-PA	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
FOCC014226-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC011253-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
FOCC017046-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC015842-PA	11	MetaCyc: PWY-7111;KEGG: 00770+2.2.1.6;MetaCyc: PWY-5103;KEGG: 00660+2.2.1.6;MetaCyc: PWY-5104;MetaCyc: PWY-5101;MetaCyc: PWY-5939;KEGG: 00290+2.2.1.6;KEGG: 00650+2.2.1.6;MetaCyc: PWY-5938;MetaCyc: PWY-6389	"Pyruvate fermentation to isobutanol (engineered)";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III";"C5-Branched dibasic acid metabolism";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"Pyruvate fermentation to (R)-acetoin II";"Valine, leucine and isoleucine biosynthesis";"Butanoate metabolism";"Pyruvate fermentation to (R)-acetoin I";"Pyruvate fermentation to (S)-acetoin"
FOCC003907-PA	15	Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-179409	"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A"
FOCC003407-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC007063-PA	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
FOCC002664-PA	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
FOCC007702-PA	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
FOCC005607-PA	12	Reactome: R-HSA-5362798;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-982772;Reactome: R-HSA-193692	"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR"
FOCC014493-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
FOCC000624-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC017027-PA	7	Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1655829	"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
FOCC005383-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC017767-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC006516-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC004550-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
FOCC011207-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC009604-PA	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
FOCC013681-PA	7	Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946	"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin"
FOCC004891-PA	5	Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)"
FOCC004317-PA	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
FOCC008536-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC001378-PA	1	Reactome: R-HSA-1483191	"Synthesis of PC"
FOCC007963-PA	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
FOCC009471-PA	5	Reactome: R-HSA-380994;Reactome: R-HSA-381042;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-381183	"ATF4 activates genes in response to endoplasmic reticulum stress";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF6 (ATF6-alpha) activates chaperone genes"
FOCC004403-PA	27	Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins"
FOCC007188-PA	10	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-6804756	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation"
FOCC013104-PA	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
FOCC011677-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC015147-PA	40	Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER"
FOCC016528-PA	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8049;MetaCyc: PWY-5971;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-7663;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-7723;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWY-5973;MetaCyc: PWY-6113;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5989;MetaCyc: PWY-7858;MetaCyc: PWY-4381;MetaCyc: PWY-8012;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5142;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;Reactome: R-HSA-75105	"Fatty acid biosynthesis";"Pederin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Superpathway of mycolate biosynthesis";"Bryostatin biosynthesis";"Biotin metabolism";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis"
FOCC006610-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
FOCC014094-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC011753-PA	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
FOCC009365-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC014339-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC014222-PA	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
FOCC008505-PA	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
FOCC014046-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
FOCC004234-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC009540-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC014393-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
FOCC001256-PA	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
FOCC008013-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
FOCC003962-PA	24	Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148	"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"Gap junction assembly";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC016542-PA	5	Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3	"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)"
FOCC008748-PA	1	Reactome: R-HSA-6783984	"Glycine degradation"
FOCC003541-PA	9	KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70263	"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis"
FOCC008685-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
FOCC000746-PA	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
FOCC005085-PA	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
FOCC004925-PA	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
FOCC008825-PA	7	Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-7255	"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)"
FOCC003156-PA	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
FOCC017239-PA	7	Reactome: R-HSA-73817;MetaCyc: PWY-7219;MetaCyc: PWY-7234;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism"
FOCC012868-PA	6	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway"
FOCC013278-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC015954-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
FOCC001157-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC006841-PA	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
FOCC000674-PA	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
FOCC016318-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC012777-PA	6	MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484	"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
FOCC016024-PA	8	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6783310	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Fanconi Anemia Pathway"
FOCC004573-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC012123-PA	3	Reactome: R-HSA-2206291;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS IIIC - Sanfilippo syndrome C";"HS-GAG degradation";"Neutrophil degranulation"
FOCC009185-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
FOCC000534-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC007182-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC010866-PA	7	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
FOCC016254-PA	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
FOCC003428-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
FOCC007190-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC003130-PA	4	Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-196741;Reactome: R-HSA-3359463	"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1"
FOCC014208-PA	10	MetaCyc: PWY-6527;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977	"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
FOCC016982-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC006858-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
FOCC016096-PA	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
FOCC005677-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC006096-PA	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
FOCC000605-PA	7	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
FOCC004528-PA	7	Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
FOCC008930-PA	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
FOCC003581-PA	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
FOCC011718-PA	10	MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7524;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;Reactome: R-HSA-1989781;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174	"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"PPARA activates gene expression";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)"
FOCC001811-PA	7	KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539	"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism"
FOCC008060-PA	14	Reactome: R-HSA-205043;Reactome: R-HSA-1474228;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-6798695;Reactome: R-HSA-193692	"NRIF signals cell death from the nucleus";"Degradation of the extracellular matrix";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Regulated proteolysis of p75NTR"
FOCC001031-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
FOCC000493-PB	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
FOCC008620-PA	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
FOCC011771-PA	5	MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome"
FOCC003920-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC006693-PA	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
FOCC011575-PA	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
FOCC004387-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
FOCC016586-PA	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
FOCC002547-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
FOCC015777-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
FOCC014149-PA	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
FOCC016433-PA	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
FOCC007625-PA	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
FOCC009481-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC016673-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC003641-PA	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
FOCC003577-PA	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events"
FOCC000625-PA	1	Reactome: R-HSA-8849175	"Threonine catabolism"
FOCC015406-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
FOCC001087-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC008468-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC012408-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
FOCC015501-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC016776-PA	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
FOCC008235-PA	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350	"Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism"
FOCC002594-PA	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
FOCC001987-PA	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
FOCC012746-PA	8	KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;Reactome: R-HSA-73614;MetaCyc: PWY-7193;MetaCyc: PWY-7181;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5	"Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism"
FOCC001257-PA	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
FOCC008692-PA	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
FOCC012963-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
FOCC015691-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
FOCC006705-PA	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
FOCC016724-PA	18	KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7003;MetaCyc: PWY-7385;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861	"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycerol degradation to butanol";"1,3-propanediol biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Pentose phosphate pathway";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
FOCC017176-PA	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
FOCC013197-PA	6	Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;Reactome: R-HSA-9615017;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Ethylene biosynthesis III (microbes)"
FOCC009603-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
FOCC016381-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC006363-PA	14	Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700	"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
FOCC000995-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC012985-PA	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6"
FOCC001361-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
FOCC017153-PA	4	Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462	"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1"
FOCC017160-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC014264-PA	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
FOCC000321-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
FOCC017611-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC017484-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
FOCC002488-PA	25	Reactome: R-HSA-380270;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148	"Recruitment of mitotic centrosome proteins and complexes";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"Cilium Assembly";"Gap junction assembly";"Kinesins";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC000266-PA	12	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6804756	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation"
FOCC008774-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
FOCC003404-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC006307-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
FOCC005236-PA	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
FOCC014519-PA	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
FOCC007737-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
FOCC009261-PA	3	KEGG: 00900+4.6.1.12;KEGG: 00900+2.7.7.60;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
FOCC001316-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC001824-PA	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
FOCC009422-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC007469-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC008581-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC002205-PA	7	Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
FOCC003181-PA	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-5620922	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium"
FOCC002142-PA	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
FOCC007214-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
FOCC015125-PA	12	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants";"Human papillomavirus infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Signaling by FGFR1 in disease";"mTOR signaling pathway"
FOCC013200-PA	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
FOCC000761-PA	13	MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II"
FOCC000133-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
FOCC016394-PA	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
FOCC005918-PA	7	Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
FOCC012569-PA	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
FOCC012799-PA	4	Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes"
FOCC007701-PA	9	Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695	"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"MAP2K and MAPK activation";"Neutrophil degranulation"
FOCC013386-PA	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
FOCC003122-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
FOCC007765-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
FOCC009637-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
FOCC002477-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC009530-PA	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC003330-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC006373-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC013505-PA	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
FOCC017769-PA	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
FOCC009165-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC002786-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC001747-PA	4	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
FOCC000938-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
FOCC001827-PA	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
FOCC007618-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC011988-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC012176-PA	11	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human papillomavirus infection"
FOCC008955-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
FOCC003961-PA	24	Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189	"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Gap junction assembly";"Kinesins"
FOCC008216-PA	3	KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
FOCC009138-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC004282-PA	4	Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374	"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
FOCC017296-PA	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
FOCC004985-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
FOCC002061-PA	4	Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation"
FOCC011088-PA	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
FOCC003137-PA	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis"
FOCC011349-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC009079-PA	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
FOCC015962-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC007028-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC015838-PA	24	Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148	"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"Gap junction assembly";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC006764-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC000747-PA	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
FOCC007129-PA	19	MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-7115;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7383	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)"
FOCC017810-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC002698-PA	3	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1"
FOCC006498-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
FOCC002716-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
FOCC007091-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
FOCC005011-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
FOCC003433-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
FOCC003853-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC016564-PA	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
FOCC002097-PA	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
FOCC005975-PA	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis"
FOCC007504-PA	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
FOCC013202-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC005068-PA	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
FOCC017361-PA	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
FOCC015874-PA	4	KEGG: 00332+1.2.1.41;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41	"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
FOCC003856-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC002848-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
FOCC005513-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC006517-PA	4	MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis"
FOCC009445-PA	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
FOCC007934-PA	5	MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
FOCC011128-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC004773-PA	14	MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-1622;MetaCyc: PWY-181;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;MetaCyc: PWY-2201	"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I"
FOCC017621-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
FOCC006763-PA	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
FOCC004312-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
FOCC000099-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC013650-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC009139-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
FOCC013758-PA	14	MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7725	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
FOCC006077-PA	5	Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357	"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling"
FOCC008396-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC013118-PA	56	Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895	"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis"
FOCC000356-PA	13	Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
FOCC014440-PA	4	Reactome: R-HSA-4755583;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108	"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
FOCC013989-PA	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
FOCC004936-PA	3	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
FOCC009585-PA	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
FOCC013373-PA	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
FOCC002609-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC000583-PA	13	MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II"
FOCC006180-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC014983-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC014467-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC012304-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
FOCC017434-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC003638-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC012005-PA	9	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
FOCC015531-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
FOCC002653-PA	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
FOCC016613-PA	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC012313-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC005786-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
FOCC001194-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC011193-PA	20	Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756	"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation"
FOCC015596-PA	12	Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607	"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends"
FOCC009047-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
FOCC005089-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC004782-PA	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
FOCC002852-PA	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
FOCC007686-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC001142-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC004651-PA	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
FOCC003415-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
FOCC003678-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
FOCC014498-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
FOCC016360-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
FOCC003812-PA	26	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-389977	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"Gap junction assembly";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway"
FOCC004887-PB	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
FOCC006943-PA	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC003766-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
FOCC017540-PA	7	MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214	"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
FOCC001681-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
FOCC010873-PA	4	MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2	"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
FOCC007390-PB	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC002574-PA	56	Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-68949	"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin"
FOCC017726-PA	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
FOCC008999-PA	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
FOCC015149-PA	58	Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-69601;Reactome: R-HSA-5689901;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764	"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Metalloprotease DUBs";"Degradation of DVL";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling"
FOCC003102-PA	7	Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-212300	"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA"
FOCC005826-PA	6	MetaCyc: PWY-4381;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-196780	"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism"
FOCC014845-PA	3	MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE"
FOCC000436-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
FOCC002378-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949664	"Mitochondrial protein import";"Processing of SMDT1"
FOCC016917-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
FOCC008911-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC002507-PA	9	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Neddylation";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER"
FOCC017300-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC012322-PA	13	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
FOCC007397-PA	40	MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00592+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5177;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-6883;MetaCyc: PWY-7726;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-5109;MetaCyc: PWY-7656;MetaCyc: PWY-6944;MetaCyc: PWY-7094;MetaCyc: PWY-7216;MetaCyc: PWY-5136;KEGG: 00903+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-5138;MetaCyc: PWY-7779;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7654;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778	"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Benzoate degradation";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to hexanol (engineered)";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"alpha-Linolenic acid metabolism";"Caprolactam degradation";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Glutaryl-coa degradation";"Propanoate metabolism";"Geraniol degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol II (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Aminobenzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fermentation to 2-methylbutanoate";"Spodoptera littoralis pheromone biosynthesis";"Androstenedione degradation";"Fatty acid salvage";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Limonene and pinene degradation";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl tert-butyl ether degradation";"Lysine degradation";"beta-Alanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Phenylalanine metabolism";"Butanoate metabolism";"Pyruvate fermentation to butanol I";"Toluene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid elongation";"2-methylpropene degradation"
FOCC014706-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC014509-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC006751-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC000448-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC016097-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC008897-PA	7	Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
FOCC017255-PA	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
FOCC002607-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC001851-PA	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
FOCC003302-PA	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis"
FOCC000387-PA	9	MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism"
FOCC011298-PA	10	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-381042;Reactome: R-HSA-72702;Reactome: R-HSA-382556;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PERK regulates gene expression";"Ribosomal scanning and start codon recognition";"ABC-family proteins mediated transport";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"L13a-mediated translational silencing of Ceruloplasmin expression"
FOCC012918-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC001381-PA	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
FOCC015966-PA	3	KEGG: 00540+3.1.3.45;MetaCyc: PWY-7674;MetaCyc: PWY-1269	"Lipopolysaccharide biosynthesis";"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
FOCC015895-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
FOCC016372-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
FOCC014490-PA	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241	"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Peroxisomal protein import"
FOCC013236-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC001654-PA	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
FOCC014471-PA	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
FOCC008278-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC007555-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
FOCC003598-PA	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
FOCC017175-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC011454-PA	4	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432720	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis"
FOCC006061-PA	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
FOCC002168-PA	24	Reactome: R-HSA-9634600;KEGG: 04150+2.7.11.11;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;Reactome: R-HSA-164378;Reactome: R-HSA-4420097;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-422356;Reactome: R-HSA-5610783;Reactome: R-HSA-9010642;Reactome: R-HSA-8853659;Reactome: R-HSA-392517;Reactome: R-HSA-163358;Reactome: R-HSA-163615;Reactome: R-HSA-5610787	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"mTOR signaling pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"PKA activation in glucagon signalling";"VEGFA-VEGFR2 Pathway";"HDL assembly";"Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Regulation of insulin secretion";"Degradation of GLI2 by the proteasome";"ROBO receptors bind AKAP5";"RET signaling";"Rap1 signalling";"PKA-mediated phosphorylation of key metabolic factors";"PKA activation";"Hedgehog 'off' state"
FOCC000433-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
FOCC005144-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC008701-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
FOCC000263-PA	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
FOCC016985-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC004526-PA	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
FOCC011704-PA	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
FOCC008809-PA	39	Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-6804115;Reactome: R-HSA-3232118;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-139915;Reactome: R-HSA-8941855;Reactome: R-HSA-6804759;Reactome: R-HSA-5628897;Reactome: R-HSA-6804114;Reactome: R-HSA-6803211;Reactome: R-HSA-2559585;Reactome: R-HSA-6803207;Reactome: R-HSA-8852276;Reactome: R-HSA-6804116;Reactome: R-HSA-111448;Reactome: R-HSA-6804760;Reactome: R-HSA-349425;Reactome: R-HSA-6785807;Reactome: R-HSA-1912408;Reactome: R-HSA-69473;Reactome: R-HSA-5689896;Reactome: R-HSA-8943724;Reactome: R-HSA-8853884;Reactome: R-HSA-6804758;Reactome: R-HSA-2559580;Reactome: R-HSA-390471;Reactome: R-HSA-6804756;Reactome: R-HSA-6803204;Reactome: R-HSA-6811555;Reactome: R-HSA-6796648;Reactome: R-HSA-2559584;Reactome: R-HSA-6804757;Reactome: R-HSA-6803205;Reactome: R-HSA-69541;Reactome: R-HSA-69895;Reactome: R-HSA-6804754	"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"SUMOylation of transcription factors";"G2/M Checkpoints";"Ub-specific processing proteases";"Activation of PUMA and translocation to mitochondria";"RUNX3 regulates CDKN1A transcription";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Metabolic Genes";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"TP53 Regulates Transcription of Death Receptors and Ligands";"Oncogene Induced Senescence";"TP53 Regulates Transcription of Caspase Activators and Caspases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest";"Activation of NOXA and translocation to mitochondria";"Regulation of TP53 Activity through Methylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-4 and Interleukin-13 signaling";"Pre-NOTCH Transcription and Translation";"G2/M DNA damage checkpoint";"Ovarian tumor domain proteases";"Regulation of PTEN gene transcription";"Transcriptional Regulation by VENTX";"Regulation of TP53 Activity through Acetylation";"Oxidative Stress Induced Senescence";"Association of TriC/CCT with target proteins during biosynthesis";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"PI5P Regulates TP53 Acetylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Senescence-Associated Heterochromatin Foci (SAHF)";"Regulation of TP53 Degradation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Stabilization of p53";"Transcriptional activation of cell cycle inhibitor p21";"Regulation of TP53 Expression"
FOCC012183-PA	18	MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4	"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Synthesis of PA";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism"
FOCC009250-PA	3	KEGG: 00740+2.5.1.78;MetaCyc: PWY-6168;MetaCyc: PWY-6167	"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"Flavin biosynthesis II (archaea)"
FOCC011098-PA	4	Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017;Reactome: R-HSA-198693	"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus"
FOCC003295-PA	4	MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
FOCC008874-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
FOCC002865-PA	1	Reactome: R-HSA-419771	"Opsins"
FOCC009267-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC015899-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC006852-PA	7	Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
FOCC003991-PA	33	MetaCyc: PWY-6802;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-3162;MetaCyc: PWY-7111;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-7798;MetaCyc: PWY-6871;MetaCyc: PWY-7013;MetaCyc: PWY-6313;MetaCyc: PWY-5057;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-7118;MetaCyc: PWY-6342;Reactome: R-HSA-71384;KEGG: 00625+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-6333;MetaCyc: PWY-5486;KEGG: 00592+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5078;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-5751;MetaCyc: PWY-1801;KEGG: 00260+1.1.1.1;KEGG: 00071+1.1.1.1	"Salidroside biosynthesis";"Naphthalene degradation";"L-leucine degradation III";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to isobutanol (engineered)";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"Protein S-nitrosylation and denitrosylation";"3-methylbutanol biosynthesis (engineered)";"(S)-propane-1,2-diol degradation";"Serotonin degradation";"L-valine degradation II";"Tyrosine metabolism";"L-methionine degradation III";"Chitin degradation to ethanol";"Noradrenaline and adrenaline degradation";"Ethanol oxidation";"Chloroalkane and chloroalkene degradation";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol I";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol II";"alpha-Linolenic acid metabolism";"Methane metabolism";"L-isoleucine degradation II";"Retinol metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"L-phenylalanine degradation III";"Phenylethanol biosynthesis";"Formaldehyde oxidation II (glutathione-dependent)";"Glycine, serine and threonine metabolism";"Fatty acid degradation"
FOCC003089-PA	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
FOCC001869-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
FOCC002312-PA	13	MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7721;MetaCyc: PWY-5123	"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
FOCC002280-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC014574-PA	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
FOCC007544-PA	5	MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
FOCC002286-PA	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC015844-PA	1	KEGG: 00290+4.2.1.33	"Valine, leucine and isoleucine biosynthesis"
FOCC003325-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC016105-PA	8	Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-196025	"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions"
FOCC007783-PA	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
FOCC003401-PA	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
FOCC000895-PA	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
FOCC000789-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
FOCC014481-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
FOCC001427-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC001872-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
FOCC006001-PA	11	Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801	"DNA replication initiation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair"
FOCC015374-PA	4	Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026	"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)"
FOCC007130-PA	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
FOCC017363-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
FOCC004627-PA	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
FOCC012761-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC005016-PA	8	KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism"
FOCC011256-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
FOCC015859-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
FOCC002719-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
FOCC005886-PA	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
FOCC014391-PA	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
FOCC007392-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC015698-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
FOCC012262-PA	3	Reactome: R-HSA-5576893;Reactome: R-HSA-1296072;Reactome: R-HSA-5576890	"Phase 2 - plateau phase";"Voltage gated Potassium channels";"Phase 3 - rapid repolarisation"
FOCC016796-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
FOCC013673-PA	14	Reactome: R-HSA-71403;Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690	"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)"
FOCC001484-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
FOCC012515-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
FOCC003423-PA	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
FOCC016970-PA	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism"
FOCC010857-PA	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
FOCC014479-PA	3	MetaCyc: PWY-1269;MetaCyc: PWY-7674;KEGG: 00540+2.5.1.55	"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis"
FOCC000512-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC001996-PA	7	KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596	"Purine metabolism";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I"
FOCC008282-PA	4	Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;MetaCyc: PWY-7282	"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
FOCC007654-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
FOCC005550-PA	3	Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722	"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
FOCC015783-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC012115-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
FOCC003309-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC005624-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC001354-PA	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
FOCC009439-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
FOCC004628-PA	4	Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC011501-PA	2	Reactome: R-HSA-8949664;Reactome: R-HSA-1268020	"Processing of SMDT1";"Mitochondrial protein import"
FOCC003083-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
FOCC001455-PA	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
FOCC002037-PA	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
FOCC014326-PA	1	Reactome: R-HSA-5676934	"Protein repair"
FOCC016198-PA	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870	"Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins"
FOCC008996-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC009368-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
FOCC009564-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
FOCC013334-PA	6	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
FOCC015343-PA	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
FOCC005206-PA	10	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint"
FOCC000031-PA	8	MetaCyc: PWY-1861;Reactome: R-HSA-71336;Reactome: R-HSA-6791055;Reactome: R-HSA-6791462;Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723;Reactome: R-HSA-8950505	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
FOCC016040-PA	4	Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20	"Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism"
FOCC006842-PA	5	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
FOCC006831-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC000865-PA	5	Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
FOCC014262-PA	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
FOCC010891-PA	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
FOCC012573-PA	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
FOCC009294-PA	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
FOCC013053-PA	16	Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-3214847;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HATs acetylate histones";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends"
FOCC018027-PA	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
FOCC002637-PA	6	KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221	"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)"
FOCC007360-PA	27	Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-167152;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-159227;Reactome: R-HSA-111367;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-77595;Reactome: R-HSA-167158;Reactome: R-HSA-191859;Reactome: R-HSA-167200;Reactome: R-HSA-159230;Reactome: R-HSA-6807505;Reactome: R-HSA-72187;Reactome: R-HSA-77588;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-975956;Reactome: R-HSA-674695;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Transport of the SLBP independent Mature mRNA";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Intronless Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"snRNP Assembly";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP Dependant Mature mRNA";"RNA polymerase II transcribes snRNA genes";"mRNA 3'-end processing";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs"
FOCC014442-PA	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
FOCC012131-PA	9	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway"
FOCC004714-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC002943-PA	5	Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895	"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
FOCC011926-PA	12	Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13	"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Cysteine and methionine metabolism"
FOCC003095-PA	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
FOCC010790-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC000025-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC017216-PA	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
FOCC015548-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
FOCC011176-PA	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
FOCC002874-PA	5	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress"
FOCC014259-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
FOCC003923-PA	14	MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-6453	"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis"
FOCC016589-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC015758-PA	11	MetaCyc: PWY-7821;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184	"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Starch and sucrose metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
FOCC004678-PA	10	Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23	"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Other glycan degradation";"Glycosaminoglycan degradation"
FOCC011392-PA	1	Reactome: R-HSA-5617833	"Cilium Assembly"
FOCC006370-PA	17	Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167242;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16;Reactome: R-HSA-674695	"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Th1 and Th2 cell differentiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway";"RNA Polymerase II Pre-transcription Events"
FOCC002580-PA	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
FOCC007060-PA	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
FOCC007167-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
FOCC006777-PA	13	Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-177504	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling"
FOCC006521-PA	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
FOCC005861-PA	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
FOCC000311-PA	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
FOCC009223-PA	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism"
FOCC013040-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC003986-PA	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22	"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism"
FOCC010901-PA	56	Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276	"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"UCH proteinases";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint"
FOCC007973-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC006072-PA	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
FOCC002863-PA	1	Reactome: R-HSA-419771	"Opsins"
FOCC010988-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC003874-PA	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-110328	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Meiotic synapsis";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
FOCC002905-PA	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
FOCC008560-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC001707-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC000564-PA	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
FOCC011990-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
FOCC013303-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC007069-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC008798-PA	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
FOCC010964-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC008056-PA	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
FOCC009077-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
FOCC004599-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC006908-PA	57	Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684	"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state"
FOCC005822-PA	14	MetaCyc: PWY-5972;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
FOCC008974-PA	2	Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
FOCC003740-PA	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
FOCC015809-PA	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC005195-PA	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
FOCC003572-PA	1	Reactome: R-HSA-163841	"Gamma carboxylation, hypusine formation and arylsulfatase activation"
FOCC012314-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC014210-PA	16	Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580	"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence"
FOCC004642-PA	16	Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1257604;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-1963640;Reactome: R-HSA-8847993;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530	"Nuclear signaling by ERBB4";"Signaling by ERBB4";"PIP3 activates AKT signaling";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"GRB2 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
FOCC001346-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
FOCC008292-PA	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
FOCC003289-PA	11	Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
FOCC002420-PA	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
FOCC000250-PA	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
FOCC008293-PB	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
FOCC017068-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC001918-PA	9	Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535	"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer"
FOCC003390-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC012057-PA	5	Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
FOCC014446-PA	6	Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria"
FOCC003518-PA	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
FOCC009454-PA	8	Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-113501	"Removal of the Flap Intermediate";"DNA replication initiation";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
FOCC000676-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
FOCC003063-PA	7	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination"
FOCC011308-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC014837-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC017335-PA	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
FOCC001275-PA	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
FOCC015707-PA	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
FOCC008801-PA	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
FOCC013044-PA	5	MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
FOCC008589-PA	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
FOCC002323-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
FOCC006664-PA	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
FOCC014738-PA	5	Reactome: R-HSA-110329;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
FOCC015671-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC003293-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
FOCC000640-PA	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
FOCC006489-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC017142-PA	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
FOCC012235-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC009210-PA	14	Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)"
FOCC007921-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
FOCC001461-PA	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
FOCC004022-PA	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC017836-PA	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC011189-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC004070-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC003502-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC004500-PA	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
FOCC005193-PA	13	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
FOCC014729-PA	3	Reactome: R-HSA-163210;Reactome: R-HSA-6787450;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"tRNA modification in the mitochondrion";"Cristae formation"
FOCC013285-PA	8	MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-2301	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis"
FOCC007443-PA	14	MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4	"Anandamide biosynthesis I";"Ether lipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
FOCC002367-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
FOCC009450-PA	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
FOCC006706-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
FOCC011282-PA	7	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
FOCC013295-PA	4	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37	"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism"
FOCC005771-PA	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
FOCC016039-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC008112-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC011096-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC003442-PA	17	Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Activation of ATR in response to replication stress";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint";"Meiotic synapsis";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
FOCC005537-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC013078-PA	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
FOCC005552-PA	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
FOCC014257-PA	8	MetaCyc: PWY-7979;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis"
FOCC000962-PA	22	MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7606;MetaCyc: PWY-7728;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5353;MetaCyc: PWY-6958;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7053;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-6433;MetaCyc: PWY-7592;MetaCyc: PWY-7619;MetaCyc: PWY-7035;KEGG: 00062+4.2.1.134	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
FOCC011402-PA	11	Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-163359	"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation"
FOCC010882-PA	1	Reactome: R-HSA-201451	"Signaling by BMP"
FOCC001279-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC012509-PA	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
FOCC010726-PA	7	Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882	"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)"
FOCC016749-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC001119-PA	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
FOCC011484-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC002426-PA	56	Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837	"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"G2/M Checkpoints";"Ub-specific processing proteases";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation"
FOCC003219-PA	8	MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5269	"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II"
FOCC005800-PA	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
FOCC011498-PA	3	KEGG: 00590+1.14.99.1;Reactome: R-HSA-140180;Reactome: R-HSA-2162123	"Arachidonic acid metabolism";"COX reactions";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
FOCC015856-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
FOCC005349-PA	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
FOCC001164-PA	1	Reactome: R-HSA-1296061	"HCN channels"
FOCC013318-PA	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
FOCC011366-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC013632-PA	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
FOCC014128-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
FOCC006484-PA	5	MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082	"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
FOCC005285-PA	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
FOCC011361-PA	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
FOCC007432-PA	5	Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144	"Endogenous sterols";"Phase I - Functionalization of compounds";"Xenobiotics";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling"
FOCC008729-PA	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
FOCC004496-PA	16	Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176407	"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
FOCC007019-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC006172-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC017331-PA	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
FOCC009085-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC003666-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC008431-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
FOCC009424-PA	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
FOCC012291-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
FOCC009013-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
FOCC014065-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC013365-PA	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
FOCC001480-PA	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
FOCC008946-PA	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
FOCC003664-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC004522-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
FOCC012312-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC016825-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC006399-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC004188-PA	5	MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855;Reactome: R-HSA-70171	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Glycolysis"
FOCC005290-PA	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
FOCC001359-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
FOCC003046-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC003631-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC013647-PA	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
FOCC013450-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
FOCC014168-PA	16	Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC012045-PA	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
FOCC005212-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC013121-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
FOCC016403-PA	11	Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"Cytosolic sensors of pathogen-associated DNA";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
FOCC004865-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC005013-PA	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
FOCC008275-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC015407-PA	5	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
FOCC009457-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
FOCC003421-PA	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
FOCC003833-PA	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
FOCC002711-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC015046-PA	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
FOCC006341-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC012955-PA	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
FOCC011136-PA	8	Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
FOCC015342-PA	1	KEGG: 00970+6.1.1.14	"Aminoacyl-tRNA biosynthesis"
FOCC000276-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC002935-PA	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
FOCC000919-PA	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
FOCC015617-PA	6	MetaCyc: PWY-7234;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124	"Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II"
FOCC015857-PA	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
FOCC014070-PA	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
FOCC008777-PA	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
FOCC013636-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC008925-PA	24	Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833	"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Gap junction assembly";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"Cilium Assembly"
FOCC012711-PA	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis"
FOCC014826-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
FOCC000076-PA	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
FOCC004300-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC001511-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
FOCC002487-PA	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
FOCC013368-PA	14	Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1632852;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295	"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Macroautophagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Intraflagellar transport";"MHC class II antigen presentation"
FOCC002306-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
FOCC002469-PA	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
FOCC002554-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC003333-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
FOCC001210-PA	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-4655427	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"DNA methylation";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins"
FOCC002958-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC008532-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC013393-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
FOCC008746-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
FOCC011543-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
FOCC004116-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC005366-PA	4	Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
FOCC006816-PA	56	Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-450408	"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
FOCC005405-PA	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)"
FOCC001231-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-210745	"Nuclear Receptor transcription pathway";"Regulation of gene expression in beta cells"
FOCC002643-PA	9	MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series"
FOCC007003-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC007186-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
FOCC012629-PA	18	MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4	"Anandamide biosynthesis II";"Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism"
FOCC017569-PA	6	KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23	"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism"
FOCC006904-PA	37	Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-983170;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-2132295;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-204005;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9639288;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-165054	"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"MHC class II antigen presentation";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"COPII-mediated vesicle transport";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Amino acids regulate mTORC1";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA"
FOCC001420-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
FOCC001782-PA	7	KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22	"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
FOCC009203-PA	5	Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation"
FOCC007780-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
FOCC007574-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
FOCC014609-PA	6	Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
FOCC001885-PA	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
FOCC012309-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC015985-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC011540-PA	4	Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
FOCC000710-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC008631-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC009573-PA	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
FOCC002380-PA	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC009590-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC004781-PA	5	Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
FOCC011512-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC008733-PA	6	KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Vitamin B6 metabolism"
FOCC003153-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC010794-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC009229-PA	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9633012	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC015380-PA	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
FOCC001934-PA	9	Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
FOCC006351-PA	7	Reactome: R-HSA-2142691;Reactome: R-HSA-9018681;Reactome: R-HSA-9018676;Reactome: R-HSA-9020265;Reactome: R-HSA-9018896;Reactome: R-HSA-9023661;Reactome: R-HSA-6798695	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of protectins";"Biosynthesis of D-series resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Neutrophil degranulation"
FOCC002446-PA	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
FOCC002895-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
FOCC004026-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
FOCC009594-PA	8	Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690	"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins";"HCMV Early Events"
FOCC011121-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC004797-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC000377-PA	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72695	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex"
FOCC004261-PA	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
FOCC006775-PA	13	Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-2871809	"Ion homeostasis";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization"
FOCC009456-PA	8	Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-68962	"Removal of the Flap Intermediate";"DNA replication initiation";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex"
FOCC015775-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC008563-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
FOCC005721-PA	57	Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974	"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway"
FOCC014287-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC016764-PA	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
FOCC004313-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
FOCC002646-PA	11	Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
FOCC007399-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC008087-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
FOCC001128-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC013094-PA	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
FOCC016240-PA	7	Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397	"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
FOCC015683-PA	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
FOCC013646-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC014964-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
FOCC008862-PA	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC015839-PA	16	MetaCyc: PWY-6387;MetaCyc: PWY-7953;MetaCyc: PWY-5265;MetaCyc: PWY-6386;Reactome: R-HSA-196757;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.129;KEGG: 00471+6.3.2.8;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;KEGG: 00550+6.3.2.8;Reactome: R-HSA-446193;KEGG: 00550+2.4.1.227;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;Reactome: R-HSA-4549356	"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Peptidoglycan biosynthesis II (staphylococci)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"Metabolism of folate and pterines";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"D-Glutamine and D-glutamate metabolism";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2"
FOCC002560-PA	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
FOCC001067-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC008509-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC014071-PA	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
FOCC013838-PA	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
FOCC012572-PA	26	Reactome: R-HSA-1362277;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6804114;Reactome: R-HSA-5655862;Reactome: R-HSA-8866654;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-4615885;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-69205;Reactome: R-HSA-5685942	"Transcription of E2F targets under negative control by DREAM complex";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLK";"E3 ubiquitin ligases ubiquitinate target proteins";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"SUMOylation of DNA replication proteins";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"G1/S-Specific Transcription";"HDR through Homologous Recombination (HRR)"
FOCC005760-PA	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
FOCC011347-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC005577-PA	4	Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-1362409	"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis"
FOCC007550-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
FOCC000413-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC011554-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC011721-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC003129-PA	5	Reactome: R-HSA-2129379;Reactome: R-HSA-3769402;Reactome: R-HSA-1474228;Reactome: R-HSA-201722;Reactome: R-HSA-1566948	"Molecules associated with elastic fibres";"Deactivation of the beta-catenin transactivating complex";"Degradation of the extracellular matrix";"Formation of the beta-catenin:TCF transactivating complex";"Elastic fibre formation"
FOCC011507-PA	5	Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012-1;MetaCyc: PWY-6289;MetaCyc: PWY-6012	"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein activation";"Petrobactin biosynthesis";"Acyl carrier protein metabolism"
FOCC002875-PA	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
FOCC013148-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC013538-PA	6	MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
FOCC010767-PA	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
FOCC012714-PA	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
FOCC001065-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC002161-PA	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
FOCC004090-PA	40	KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7654;KEGG: 00360+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7656;MetaCyc: PWY-6944;MetaCyc: PWY-7216;MetaCyc: PWY-5136;MetaCyc: PWY-7094;MetaCyc: PWY-5109;MetaCyc: PWY-6435;MetaCyc: PWY-7726;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-7401;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5177;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-5789;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7007	"Fatty acid elongation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Toluene degradation";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Phenylalanine metabolism";"beta-Alanine metabolism";"Pyruvate fermentation to butanol I";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Limonene and pinene degradation";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Spodoptera littoralis pheromone biosynthesis";"Androstenedione degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid salvage";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Propanoate metabolism";"Geraniol degradation";"Benzoyl-coa degradation I (aerobic)";"Glutaryl-coa degradation";"Fatty acid degradation";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to hexanol (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)"
FOCC000675-PA	1	Reactome: R-HSA-176974	"Unwinding of DNA"
FOCC004201-PA	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
FOCC016245-PA	7	Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER"
FOCC016219-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC005950-PA	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
FOCC001502-PA	5	Reactome: R-HSA-75109;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Triglyceride biosynthesis";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
FOCC004919-PA	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
FOCC007198-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
FOCC014929-PA	5	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
FOCC012302-PA	4	Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
FOCC003296-PA	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
FOCC009529-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC000131-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC002840-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
FOCC012994-PA	5	Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)"
FOCC004329-PA	1	Reactome: R-HSA-3295583	"TRP channels"
FOCC017364-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
FOCC016348-PA	10	Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111463	"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs"
FOCC014512-PA	2	Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
FOCC000018-PA	5	KEGG: 00240+2.4.2.4;MetaCyc: PWY-7181;KEGG: 00983+2.4.2.4;Reactome: R-HSA-73621;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage"
FOCC005579-PA	1	Reactome: R-HSA-1483166	"Synthesis of PA"
FOCC000666-PA	7	MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;MetaCyc: PWY-6471;Reactome: R-HSA-446193	"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
FOCC009589-PA	5	Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
FOCC005617-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
FOCC013546-PA	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
FOCC014331-PA	20	MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337	"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)"
FOCC008657-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC015806-PA	5	Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857	"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation";"Keratan sulfate degradation"
FOCC001439-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
FOCC013856-PA	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
FOCC009534-PA	10	Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459	"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
FOCC008929-PA	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
FOCC002150-PA	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829	"Late endosomal microautophagy";"Aggrephagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy"
FOCC012345-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
FOCC009234-PA	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
FOCC001829-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC007076-PA	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
FOCC011391-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC003478-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
FOCC007146-PA	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
FOCC013067-PA	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
FOCC006668-PA	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
FOCC000878-PA	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
FOCC014531-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC000348-PA	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
FOCC012094-PA	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
FOCC001097-PA	16	Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-3214847	"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HATs acetylate histones"
FOCC017522-PA	1	Reactome: R-HSA-112314	"Neurotransmitter receptors and postsynaptic signal transmission"
FOCC002165-PA	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network"
FOCC002341-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
FOCC013860-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC007502-PA	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
FOCC006057-PA	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
FOCC007438-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC006526-PA	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
FOCC009199-PA	4	Reactome: R-HSA-4085001;KEGG: 00600+3.2.1.18;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.18	"Sialic acid metabolism";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation"
FOCC014878-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
FOCC007450-PA	5	Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
FOCC014303-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC014136-PA	1	Reactome: R-HSA-419771	"Opsins"
FOCC001878-PA	7	Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-381070	"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"IRE1alpha activates chaperones"
FOCC008552-PA	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
FOCC008489-PA	4	Reactome: R-HSA-1799339;Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation"
FOCC012303-PA	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206296;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS II - Hunter syndrome";"HS-GAG degradation"
FOCC000883-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
FOCC017626-PA	3	Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080	"Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)"
FOCC006423-PA	8	Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693579	"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange"
FOCC005169-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC002235-PA	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
FOCC017610-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC009518-PA	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
FOCC009239-PA	14	Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5696397	"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER"
FOCC007768-PA	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
FOCC000459-PA	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
FOCC013394-PA	4	MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1	"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
FOCC004962-PA	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
FOCC000048-PA	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
FOCC005688-PA	57	Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837	"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"G2/M Checkpoints";"Ub-specific processing proteases";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Interleukin-1 signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation"
FOCC005894-PA	6	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1"
FOCC002408-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
FOCC009426-PA	13	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC013466-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC009580-PA	13	MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;Reactome: R-HSA-156590;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1	"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism"
FOCC012366-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC008225-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
FOCC006337-PA	4	Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546	"Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling"
FOCC007407-PA	13	Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC002333-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
FOCC009050-PA	16	Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-167152;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167200	"HIV elongation arrest and recovery";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV elongation complex in the absence of HIV Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
FOCC003742-PA	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
FOCC011805-PA	16	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC010759-PA	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
FOCC010806-PA	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
FOCC001057-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC012490-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC000952-PA	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC000578-PA	7	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-606279	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere"
FOCC003143-PA	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC017593-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC012369-PA	32	Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery"
FOCC015027-PA	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
FOCC012403-PA	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
FOCC014049-PA	20	MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7854;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-7338	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)"
FOCC004531-PA	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
FOCC016729-PA	4	MetaCyc: PWY-6834;MetaCyc: PWY-40;MetaCyc: PWY-43;KEGG: 00330+4.1.1.19	"Spermidine biosynthesis III";"Putrescine biosynthesis I";"Putrescine biosynthesis II";"Arginine and proline metabolism"
FOCC017158-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
FOCC013068-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
FOCC004639-PA	13	KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1	"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism"
FOCC000655-PA	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
FOCC008543-PA	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
FOCC012953-PA	9	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 00500+3.2.1.28;KEGG: 05163+2.7.11.1;Reactome: R-HSA-189085;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Starch and sucrose metabolism";"Human cytomegalovirus infection";"Digestion of dietary carbohydrate";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
FOCC001272-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
FOCC000864-PA	5	Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression"
FOCC014754-PA	4	MetaCyc: PWY-6163;KEGG: 00400+2.7.1.71;KEGG: 00030+2.7.1.12;MetaCyc: PWY-5530	"Chorismate biosynthesis from 3-dehydroquinate";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Pentose phosphate pathway";"Sorbitol biosynthesis II"
FOCC014411-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC009121-PA	16	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
FOCC017242-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
FOCC003019-PA	6	Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
FOCC017354-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
FOCC006133-PA	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
FOCC005650-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC015000-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids"
FOCC008442-PA	4	Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-186763	"MET receptor recycling";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"Downstream signal transduction"
FOCC001270-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
FOCC005921-PA	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
FOCC007199-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC004169-PA	3	KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
FOCC000511-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC016644-PA	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
FOCC002964-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC002209-PA	52	Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-76061;Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-1834949;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167161	"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cytosolic sensors of pathogen-associated DNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation"
FOCC012920-PA	3	Reactome: R-HSA-71262;MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8	"Carnitine synthesis";"L-carnitine biosynthesis";"Lysine degradation"
FOCC005932-PA	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
FOCC013785-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC014884-PA	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors"
FOCC004187-PA	6	MetaCyc: PWY-5664;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6983	"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis"
FOCC015032-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
FOCC006414-PA	6	MetaCyc: PWY-7391;Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33	"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis"
FOCC006909-PA	57	Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8939236	"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"UCH proteinases";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
FOCC002402-PA	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events"
FOCC009173-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC011984-PA	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
FOCC016799-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC002599-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC005858-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
FOCC009132-PA	8	Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507	"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation"
FOCC006687-PA	14	Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418	"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex"
FOCC011912-PA	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
FOCC016210-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
FOCC016489-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
FOCC002567-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
FOCC000829-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
FOCC007935-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC004816-PA	6	Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Neutrophil degranulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
FOCC002466-PA	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
FOCC007528-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
FOCC011362-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC004959-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC016726-PA	10	MetaCyc: PWY-6892;KEGG: 00030+2.2.1.1;KEGG: 00710+2.2.1.1;MetaCyc: PWY-5723;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6901;KEGG: 00900+2.2.1.7;MetaCyc: PWY-1861	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Superpathway of glucose and xylose degradation";"Terpenoid backbone biosynthesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
FOCC011466-PA	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
FOCC008910-PA	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
FOCC016390-PA	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
FOCC006515-PA	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC014965-PA	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
FOCC001123-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC008928-PA	4	Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-186763	"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Downstream signal transduction"
FOCC001796-PA	26	Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-9609690	"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Cilium Assembly";"Kinesins";"Gap junction assembly";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events"
FOCC001576-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
FOCC006905-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC004249-PA	4	Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
FOCC017909-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC000398-PA	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
FOCC008326-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC009316-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC002766-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
FOCC000966-PA	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC017663-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
FOCC000307-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC011519-PA	11	Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568	"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
FOCC007649-PA	6	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA"
FOCC014846-PA	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
FOCC004544-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
FOCC000032-PA	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
FOCC004940-PA	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange"
FOCC015044-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
FOCC003480-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
FOCC008684-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC014486-PA	5	MetaCyc: PWY-7674;KEGG: 00540+2.5.1.55;MetaCyc: PWY-6164;MetaCyc: PWY-1269;KEGG: 00400+2.5.1.54	"CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis";"3-dehydroquinate biosynthesis I";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis"
FOCC014377-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
FOCC015799-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC017066-PA	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
FOCC001644-PA	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
FOCC011071-PA	40	Reactome: R-HSA-8851708;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-72086	"Signaling by FGFR2 IIIa TM";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping"
FOCC007246-PA	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-202433	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules"
FOCC001356-PA	6	MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
FOCC004259-PA	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
FOCC007241-PA	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC003477-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC007358-PA	27	Reactome: R-HSA-111367;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-77595;Reactome: R-HSA-167158;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-72187;Reactome: R-HSA-77588;Reactome: R-HSA-72203;Reactome: R-HSA-975956;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-167152;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-159227	"SLBP independent Processing of Histone Pre-mRNAs";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Intronless Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"mRNA 3'-end processing";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Capped Intron-Containing Pre-mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Transport of the SLBP independent Mature mRNA"
FOCC006547-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC017544-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC000357-PA	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
FOCC000653-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC007876-PA	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
FOCC013465-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC001833-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
FOCC005508-PA	5	MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
FOCC017853-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
FOCC004963-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC002665-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
FOCC014842-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC010825-PA	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
FOCC011122-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
FOCC014480-PA	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
FOCC014610-PA	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
FOCC007880-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC014662-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC014082-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC003023-PA	6	MetaCyc: PWY-6737;MetaCyc: PWY-6731;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1	"Starch degradation V";"Starch degradation III";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch and sucrose metabolism"
FOCC000070-PA	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
FOCC012334-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
FOCC007889-PA	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
FOCC006206-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC008659-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC002842-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC005067-PA	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5972	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)"
FOCC017644-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC009546-PA	11	Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-9018519;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201	"RORA activates gene expression";"Nuclear Receptor transcription pathway";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"Estrogen-dependent gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis"
FOCC005008-PA	15	Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-9603505;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"NTRK3 as a dependence receptor";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
FOCC004002-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC015529-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
FOCC017999-PA	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
FOCC015796-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC003308-PA	4	KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
FOCC013595-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
FOCC003431-PA	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
FOCC000685-PA	5	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1"
FOCC018006-PA	26	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Gap junction assembly";"Kinesins";"MHC class II antigen presentation";"Cilium Assembly";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint"
FOCC004583-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
FOCC007978-PA	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
FOCC003913-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
FOCC016976-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC012610-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC002354-PA	3	Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
FOCC012306-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC001647-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC012766-PA	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
FOCC000058-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC005748-PA	11	Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange"
FOCC011809-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC002517-PA	10	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation"
FOCC001743-PA	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
FOCC001032-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC005986-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
FOCC015727-PA	4	Reactome: R-HSA-8950505;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response"
FOCC011829-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
FOCC011576-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
FOCC012546-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC005241-PA	14	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-165054	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA"
FOCC011223-PA	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
FOCC007491-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC009198-PA	4	Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722	"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)"
FOCC012820-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC007038-PA	3	Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00515+2.7.1.183	"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
FOCC008462-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC005070-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC011255-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
FOCC010809-PA	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
FOCC009012-PA	5	Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183	"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes"
FOCC006969-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC002531-PA	15	Reactome: R-HSA-9664565;Reactome: R-HSA-9665246;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-9652282;Reactome: R-HSA-9665249;Reactome: R-HSA-9665247;Reactome: R-HSA-9634285;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-9665233;Reactome: R-HSA-9665251	"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to neratinib";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to lapatinib"
FOCC003875-PA	6	Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
FOCC009389-PA	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
FOCC014970-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC002281-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC002814-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC013536-PA	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
FOCC007909-PA	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
FOCC009330-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC015029-PA	7	Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
FOCC007258-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC017372-PA	12	MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171	"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Glycolysis"
FOCC003336-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
FOCC015589-PA	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
FOCC012407-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC017309-PA	4	Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241	"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism";"Propanoate metabolism";"Peroxisomal protein import"
FOCC003737-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC007243-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
FOCC002729-PA	13	KEGG: 04070+3.1.4.11;Reactome: R-HSA-9027277;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;Reactome: R-HSA-2029485	"Phosphatidylinositol signaling system";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"Role of phospholipids in phagocytosis"
FOCC006917-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
FOCC003391-PA	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
FOCC005873-PA	14	MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-6453	"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis"
FOCC015120-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC005740-PA	8	Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Macroautophagy";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
FOCC005733-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
FOCC001416-PA	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
FOCC000423-PA	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
FOCC007236-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC003167-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
FOCC015820-PA	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
FOCC004525-PA	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
FOCC014739-PA	8	KEGG: 00997+2.3.1.30;MetaCyc: PWY-7274;Reactome: R-HSA-446205;MetaCyc: PWY-8071;KEGG: 00270+2.3.1.30;KEGG: 00920+2.3.1.30;MetaCyc: PWY-6936;MetaCyc: PWY-7870	"Biosynthesis of various secondary metabolites - part 3";"D-cycloserine biosynthesis";"Synthesis of GDP-mannose";"N-3-oxalyl-L-2,3-diaminopropanoate biosynthesis";"Cysteine and methionine metabolism";"Sulfur metabolism";"Seleno-amino acid biosynthesis (plants)";"L-cysteine biosynthesis VII (from S-sulfo-L-cysteine)"
FOCC001122-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC012018-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC006586-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC011114-PA	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
FOCC011445-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
FOCC016753-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
FOCC005664-PA	34	Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-69231;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-69202;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Cyclin E associated events during G1/S transition";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex"
FOCC013086-PA	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC011853-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
FOCC002893-PA	14	Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-426486	"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis"
FOCC004764-PA	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
FOCC012710-PA	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes"
FOCC014869-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
FOCC015872-PA	10	MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061	"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I"
FOCC005120-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
FOCC005551-PA	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
FOCC016567-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC004365-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
FOCC009577-PA	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
FOCC007156-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC016728-PA	3	MetaCyc: PWY-40;KEGG: 00330+3.5.3.11;Reactome: R-HSA-351143	"Putrescine biosynthesis I";"Arginine and proline metabolism";"Agmatine biosynthesis"
FOCC014295-PA	13	Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-3000157;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-186797	"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Laminin interactions";"Crosslinking of collagen fibrils";"Extracellular matrix organization";"Collagen degradation";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"NCAM1 interactions";"Signaling by PDGF"
FOCC014604-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
FOCC002692-PA	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6606	"Purine metabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II"
FOCC017556-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC009258-PA	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
FOCC005534-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC009256-PA	6	MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00970+6.1.1.7	"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Aminoacyl-tRNA biosynthesis"
FOCC009432-PA	7	KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351	"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
FOCC016060-PA	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
FOCC012049-PA	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC012257-PA	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
FOCC000854-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC002317-PA	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
FOCC015953-PA	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
FOCC016459-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
FOCC004516-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
FOCC009169-PA	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA"
FOCC008610-PA	13	MetaCyc: PWY-7198;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
FOCC002329-PA	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC002522-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
FOCC008697-PA	3	Reactome: R-HSA-4086400;Reactome: R-HSA-4608870;Reactome: R-HSA-373080	"PCP/CE pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)"
FOCC012365-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC004820-PA	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
FOCC009089-PA	31	MetaCyc: PWY-5971;MetaCyc: PWYG-321;MetaCyc: PWY-8049;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7663;MetaCyc: PWY-5994;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWY-5973;MetaCyc: PWY-4381;MetaCyc: PWY-8012;MetaCyc: PWY-5989;MetaCyc: PWY-7858;MetaCyc: PWY-7664;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-6799;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-5142;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;MetaCyc: PWY-5147	"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"Pederin biosynthesis";"Fatty acid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mupirocin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)"
FOCC004110-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC011183-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC003623-PA	3	Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12	"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism"
FOCC003395-PA	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
FOCC014890-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC009309-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
FOCC016112-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC014134-PA	32	Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-6803529	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing"
FOCC014996-PA	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
FOCC012917-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC014932-PA	11	Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9013700	"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
FOCC006950-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC005804-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC008827-PA	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC007430-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
FOCC000246-PA	7	MetaCyc: PWY-8052;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204	"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
FOCC002259-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
FOCC012089-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC002663-PA	7	Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;Reactome: R-HSA-9033241;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4	"Synthesis of Ketone Bodies";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Peroxisomal protein import";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism"
FOCC009428-PA	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2465910	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"MASTL Facilitates Mitotic Progression"
FOCC001815-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC008696-PA	6	KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290	"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis"
FOCC000704-PA	11	MetaCyc: PWY-6596;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6999;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6538;Reactome: R-HSA-8851680;MetaCyc: PWY-6607	"Adenosine nucleotides degradation I";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I"
FOCC017257-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC003519-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
FOCC015482-PA	6	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC015510-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
FOCC014042-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
FOCC003497-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC011138-PA	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
FOCC013638-PA	26	Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-190861	"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Cilium Assembly";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Gap junction assembly"
FOCC005278-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC016731-PA	3	KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043	"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis"
FOCC004518-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC003807-PA	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
FOCC012016-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
FOCC003430-PA	19	Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-975634	"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"LDL remodeling";"VLDL assembly";"Chylomicron assembly";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Post-translational protein phosphorylation";"VLDL clearance";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"LDL clearance";"Retinoid metabolism and transport"
FOCC017284-PA	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis"
FOCC014520-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC005093-PA	5	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins"
FOCC017608-PA	1	Reactome: R-HSA-211981	"Xenobiotics"
FOCC007807-PA	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
FOCC011764-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC012723-PA	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
FOCC003109-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC016785-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC001238-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC006863-PA	1	Reactome: R-HSA-977347	"Serine biosynthesis"
FOCC004379-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC008069-PA	1	Reactome: R-HSA-5689603	"UCH proteinases"
FOCC001435-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
FOCC006254-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
FOCC000715-PA	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
FOCC001650-PA	1	Reactome: R-HSA-191859	"snRNP Assembly"
FOCC005385-PA	12	MetaCyc: PWY-5871;MetaCyc: PWY-5870;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-6978;Reactome: R-HSA-1268020	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import"
FOCC014951-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC005801-PA	13	MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Purine metabolism";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
FOCC003627-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
FOCC008229-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC003906-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC003500-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
FOCC010977-PA	57	Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-532668	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Neddylation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
FOCC004415-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC006148-PA	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
FOCC012102-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
FOCC001479-PA	3	Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol"
FOCC006946-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC007888-PA	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
FOCC003723-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
FOCC003134-PA	6	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC012214-PA	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
FOCC017661-PA	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
FOCC008816-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC011662-PA	6	MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840	"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Rho GTPase cycle"
FOCC014725-PA	5	MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
FOCC007608-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC005993-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC017592-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC005135-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC001935-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC002876-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC005358-PA	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
FOCC001866-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
FOCC014844-PA	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
FOCC001298-PA	29	Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5696395;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-6783310;Reactome: R-HSA-5358606	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Meiotic recombination";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Formation of Incision Complex in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Fanconi Anemia Pathway";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
FOCC014998-PA	3	KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286	"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation"
FOCC009043-PA	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
FOCC002444-PA	8	MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241	"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
FOCC016467-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC006911-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC017957-PA	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
FOCC000939-PA	8	Reactome: R-HSA-380284;Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
FOCC012420-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
FOCC011774-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC000395-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC014987-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC015340-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC000838-PA	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
FOCC004060-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC015349-PA	22	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-5685938;KEGG: 00590+3.1.1.4;Reactome: R-HSA-5693554;KEGG: 00592+3.1.1.32+3.1.1.4;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;MetaCyc: PWY-8051;MetaCyc: PWY-7417;Reactome: R-HSA-5685942;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.32+3.1.1.4;Reactome: R-HSA-5693568;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"HDR through Single Strand Annealing (SSA)";"Arachidonic acid metabolism";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"alpha-Linolenic acid metabolism";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"HDR through Homologous Recombination (HRR)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
FOCC014535-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
FOCC013390-PA	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
FOCC001112-PA	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
FOCC005852-PA	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
FOCC002034-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
FOCC014572-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
FOCC016983-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC002369-PA	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
FOCC015091-PA	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
FOCC014251-PA	29	Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-674695	"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events"
FOCC014749-PA	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24	"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
FOCC016908-PA	26	Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"Cilium Assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
FOCC011158-PA	5	Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-879415	"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling"
FOCC016178-PA	4	Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC006685-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
FOCC001922-PA	6	Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
FOCC014489-PA	5	Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-6798695	"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation"
FOCC007817-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC013594-PA	56	Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Neddylation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling"
FOCC010841-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC013802-PA	5	KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88	"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism"
FOCC018034-PA	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
FOCC009167-PA	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
FOCC006937-PA	12	MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-7230;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5856	"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
FOCC001038-PA	5	KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68	"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis"
FOCC016715-PA	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
FOCC007564-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC008558-PA	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
FOCC005987-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC013508-PA	4	KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801	"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion"
FOCC012347-PA	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
FOCC007275-PA	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC016425-PA	13	KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-8086;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-561;MetaCyc: PWY-5913	"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)"
FOCC012856-PA	12	Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861	"Gluconeogenesis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
FOCC017691-PA	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
FOCC003900-PA	7	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth"
FOCC014569-PA	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
FOCC004218-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
FOCC008672-PA	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
FOCC012678-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC017041-PA	7	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC"
FOCC014319-PA	1	Reactome: R-HSA-3065679	"SUMO is proteolytically processed"
FOCC009026-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC008570-PA	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
FOCC010746-PA	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
FOCC009249-PA	5	KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;MetaCyc: PWY-6892	"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
FOCC002679-PA	33	Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159231	"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript"
FOCC001730-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
FOCC004254-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC012940-PA	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate"
FOCC000437-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC001836-PA	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
FOCC002897-PA	4	Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-111465	"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins"
FOCC000934-PA	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
FOCC010789-PA	6	Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-6898;MetaCyc: PWY-7356;MetaCyc: PWY-6907;KEGG: 00730+2.7.6.2	"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism"
FOCC001990-PA	7	MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469	"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis"
FOCC000767-PA	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
FOCC009474-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC004405-PA	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
FOCC013840-PA	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression"
FOCC008404-PA	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817	"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
FOCC016974-PA	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC004151-PA	3	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-389661	"VLDL assembly";"Chylomicron assembly";"Glyoxylate metabolism and glycine degradation"
FOCC017380-PA	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
FOCC004688-PA	17	Reactome: R-HSA-2173796;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-1362277;Reactome: R-HSA-1912408;Reactome: R-HSA-111448;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-9616222;Reactome: R-HSA-2559585;Reactome: R-HSA-6804114;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-139915;Reactome: R-HSA-69231	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by DREAM complex";"Pre-NOTCH Transcription and Translation";"Activation of NOXA and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcriptional regulation of granulopoiesis";"Oncogene Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of PUMA and translocation to mitochondria";"Cyclin D associated events in G1"
FOCC016602-PA	6	MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
FOCC005976-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC014893-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC004103-PA	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
FOCC017496-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC006596-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
FOCC014482-PA	5	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
FOCC011016-PA	3	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
FOCC014631-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC015708-PA	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099	"Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling"
FOCC005388-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
FOCC009240-PA	7	MetaCyc: PWY-6605;MetaCyc: PWY-7805;MetaCyc: PWY-7807;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217	"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Adenine salvage";"Neutrophil degranulation";"Purine metabolism";"Purine salvage"
FOCC003006-PA	14	MetaCyc: PWY-1622;MetaCyc: PWY-181;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1	"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I";"Methane metabolism";"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate"
FOCC013504-PA	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
FOCC000278-PA	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
FOCC011708-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC007100-PA	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
FOCC005382-PA	13	Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC013367-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
FOCC015447-PA	4	MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040	"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis"
FOCC014276-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC008588-PA	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
FOCC015503-PA	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling"
FOCC012598-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC000293-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC015121-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC008985-PA	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
FOCC002903-PA	4	KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
FOCC015544-PA	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
FOCC003555-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC004299-PA	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
FOCC009297-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
FOCC013378-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC015028-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
FOCC011954-PA	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
FOCC002818-PA	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
FOCC002598-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
FOCC006422-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC003075-PA	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
FOCC011323-PA	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
FOCC001989-PA	7	MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation"
FOCC017412-PA	6	MetaCyc: PWY-6599;KEGG: 00230+2.4.2.8;MetaCyc: PWY-6620;MetaCyc: PWY-6609;KEGG: 00983+2.4.2.8;MetaCyc: PWY-6610	"Guanine and guanosine salvage II";"Purine metabolism";"Guanine and guanosine salvage";"Adenine and adenosine salvage III";"Drug metabolism - other enzymes";"Adenine salvage"
FOCC004903-PA	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
FOCC004263-PA	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
FOCC008664-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC001568-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC009078-PA	7	KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219	"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
FOCC007493-PA	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
FOCC008208-PA	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
FOCC015477-PA	11	KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913	"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)"
FOCC000466-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC001825-PA	9	MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-112043;Reactome: R-HSA-416476	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"G alpha (q) signalling events"
FOCC007250-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC004118-PA	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
FOCC002764-PA	6	Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166	"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA"
FOCC005119-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
FOCC011257-PA	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
FOCC014405-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC016386-PA	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
FOCC008654-PA	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
FOCC006833-PA	13	MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5538	"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI"
FOCC004288-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC004670-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC007372-PA	182	Reactome: R-HSA-9033241;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-168927;Reactome: R-HSA-5696400;Reactome: R-HSA-3785653;Reactome: R-HSA-174113;Reactome: R-HSA-5685942;Reactome: R-HSA-8854050;Reactome: R-HSA-2173788;Reactome: R-HSA-8866654;Reactome: R-HSA-983168;Reactome: R-HSA-5357956;Reactome: R-HSA-180585;Reactome: R-HSA-5689877;Reactome: R-HSA-975957;Reactome: R-HSA-5656169;Reactome: R-HSA-6781827;Reactome: R-HSA-5632684;Reactome: R-HSA-936440;Reactome: R-HSA-349425;Reactome: R-HSA-1253288;Reactome: R-HSA-1169408;Reactome: R-HSA-6804760;Reactome: R-HSA-5684264;Reactome: R-HSA-5668541;Reactome: R-HSA-4641263;Reactome: R-HSA-917937;Reactome: R-HSA-9010553;Reactome: R-HSA-5655862;Reactome: R-HSA-174184;Reactome: R-HSA-6782135;Reactome: R-HSA-2122947;Reactome: R-HSA-69481;Reactome: R-HSA-9633012;Reactome: R-HSA-4641257;Reactome: R-HSA-912631;Reactome: R-HSA-2565942;Reactome: R-HSA-205043;Reactome: R-HSA-450302;Reactome: R-HSA-5678895;Reactome: R-HSA-72706;Reactome: R-HSA-9604323;Reactome: R-HSA-6782210;Reactome: R-HSA-6791226;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-162588;Reactome: R-HSA-5654733;Reactome: R-HSA-5362768;Reactome: R-HSA-2559582;Reactome: R-HSA-9637628;Reactome: R-HSA-382556;Reactome: R-HSA-209543;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-937041;Reactome: R-HSA-2559580;Reactome: R-HSA-8948747;Reactome: R-HSA-400253;Reactome: R-HSA-2979096;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-975956;Reactome: R-HSA-1295596;Reactome: R-HSA-2559585;Reactome: R-HSA-69017;Reactome: R-HSA-201681;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-2173795;Reactome: R-HSA-1799339;Reactome: R-HSA-5693607;Reactome: R-HSA-937072;Reactome: R-HSA-8866652;Reactome: R-HSA-168928;Reactome: R-HSA-211733;Reactome: R-HSA-72689;Reactome: R-HSA-69601;Reactome: R-HSA-9636383;Reactome: R-HSA-8863795;Reactome: R-HSA-917729;Reactome: R-HSA-175474;Reactome: R-HSA-156827;Reactome: R-HSA-5656121;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8849469;Reactome: R-HSA-975144;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-936964;Reactome: R-HSA-6781823;Reactome: R-HSA-1236382;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-5654732;Reactome: R-HSA-69541;Reactome: R-HSA-6804757;Reactome: R-HSA-72764;Reactome: R-HSA-937039;Reactome: R-HSA-9013973;Reactome: R-HSA-532668;Reactome: R-HSA-68827;Reactome: R-HSA-1358803;Reactome: R-HSA-977225;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-110314;Reactome: R-HSA-8875360;Reactome: R-HSA-5654727;Reactome: R-HSA-179409;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-182971;Reactome: R-HSA-5675221;Reactome: R-HSA-3134975;Reactome: R-HSA-975110;Reactome: R-HSA-9646399;Reactome: R-HSA-156902;Reactome: R-HSA-2173796;Reactome: R-HSA-2691232;Reactome: R-HSA-3322077;Reactome: R-HSA-5357905;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-4608870;Reactome: R-HSA-901032;Reactome: R-HSA-8948751;Reactome: R-HSA-168638;Reactome: R-HSA-5696394;Reactome: R-HSA-72702;Reactome: R-HSA-187577;Reactome: R-HSA-8856825;Reactome: R-HSA-5675482;Reactome: R-HSA-5696397;Reactome: R-HSA-8876493;Reactome: R-HSA-192823;Reactome: R-HSA-6804756;Reactome: R-HSA-6807004;Reactome: R-HSA-5689896;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-174048;Reactome: R-HSA-9613829;Reactome: R-HSA-5696395;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-2173791;Reactome: R-HSA-174490;Reactome: R-HSA-68949;Reactome: R-HSA-8856828;Reactome: R-HSA-110320;Reactome: R-HSA-2122948;Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-9615710;Reactome: R-HSA-110312;Reactome: R-HSA-209560;Reactome: R-HSA-3769402;Reactome: R-HSA-69231;Reactome: R-HSA-6783310;Reactome: R-HSA-5610783;Reactome: R-HSA-5693565;Reactome: R-HSA-450408;Reactome: R-HSA-5205685;Reactome: R-HSA-1236974;Reactome: R-HSA-2408557;Reactome: R-HSA-2672351;Reactome: R-HSA-5654726;Reactome: R-HSA-9014325;Reactome: R-HSA-5689901;Reactome: R-HSA-8939236;Reactome: R-HSA-2644606;Reactome: R-HSA-195253	"Peroxisomal protein import";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1, RIP1-mediated IKK complex recruitment";"Dual Incision in GG-NER";"Myoclonic epilepsy of Lafora";"SCF-beta-TrCP mediated degradation of Emi1";"HDR through Homologous Recombination (HRR)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downregulation of TGF-beta receptor signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR1-induced NFkappaB signaling pathway";"Vif-mediated degradation of APOBEC3G";"Josephin domain DUBs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Termination of translesion DNA synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Hedgehog 'on' state";"Negative regulators of DDX58/IFIH1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downregulation of ERBB4 signaling";"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Methylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of FZD by ubiquitination";"Iron uptake and transport";"Regulation of expression of SLITs and ROBOs";"Translesion synthesis by POLK";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dual incision in TC-NER";"NOTCH1 Intracellular Domain Regulates Transcription";"G2/M Checkpoints";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Degradation of AXIN";"Regulation of signaling by CBL";"Regulation of PLK1 Activity at G2/M Transition";"NRIF signals cell death from the nucleus";"activated TAK1 mediates p38 MAPK activation";"Defective CFTR causes cystic fibrosis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Negative regulation of NOTCH4 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Major pathway of rRNA processing in the nucleolus and cytosol";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Budding and maturation of HIV virion";"Negative regulation of FGFR4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Senescence-Associated Secretory Phenotype (SASP)";"Modulation by Mtb of host immune system";"ABC-family proteins mediated transport";"p75NTR recruits signalling complexes";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"IKK complex recruitment mediated by RIP1";"Oxidative Stress Induced Senescence";"Regulation of PTEN localization";"Circadian Clock";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Spry regulation of FGF signaling";"Oncogene Induced Senescence";"CDK-mediated phosphorylation and removal of Cdc6";"TCF dependent signaling in response to WNT";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SRP-dependent cotranslational protein targeting to membrane";"Processing of DNA double-strand break ends";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Formation of a pool of free 40S subunits";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Prevention of phagosomal-lysosomal fusion";"Downregulation of ERBB2 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Assembly Of The HIV Virion";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translesion synthesis by POLI";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Formation of TC-NER Pre-Incision Complex";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"Negative regulation of FGFR3 signaling";"Stabilization of p53";"Regulation of TP53 Degradation";"Eukaryotic Translation Termination";"IRAK1 recruits IKK complex";"TICAM1-dependent activation of IRF3/IRF7";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"CDT1 association with the CDC6:ORC:origin complex";"Downregulation of ERBB2:ERBB3 signaling";"Amyloid fiber formation";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of FGFR2 signaling";"APC-Cdc20 mediated degradation of Nek2A";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"EGFR downregulation";"Negative regulation of MAPK pathway";"Regulation of innate immune responses to cytosolic DNA";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Aggrephagy";"Peptide chain elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Glycogen synthesis";"Regulation of TNFR1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Asymmetric localization of PCP proteins";"ER Quality Control Compartment (ERQC)";"Regulation of PTEN stability and activity";"NOD1/2 Signaling Pathway";"DNA Damage Recognition in GG-NER";"Ribosomal scanning and start codon recognition";"SCF(Skp2)-mediated degradation of p27/p21";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of necroptotic cell death";"Gap-filling DNA repair synthesis and ligation in GG-NER";"InlA-mediated entry of Listeria monocytogenes into host cells";"Viral mRNA Translation";"Regulation of TP53 Activity through Phosphorylation";"Negative regulation of MET activity";"Ovarian tumor domain proteases";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Cyclin B";"Chaperone Mediated Autophagy";"Formation of Incision Complex in GG-NER";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Membrane binding and targetting of GAG proteins";"Orc1 removal from chromatin";"Clathrin-mediated endocytosis";"Translesion Synthesis by POLH";"Activated NOTCH1 Transmits Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"Late endosomal microautophagy";"Translesion synthesis by REV1";"NF-kB is activated and signals survival";"Deactivation of the beta-catenin transactivating complex";"Cyclin D associated events in G1";"Fanconi Anemia Pathway";"Degradation of GLI2 by the proteasome";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Pink/Parkin Mediated Mitophagy";"ER-Phagosome pathway";"Selenocysteine synthesis";"Stimuli-sensing channels";"Negative regulation of FGFR1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Metalloprotease DUBs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex"
FOCC005719-PB	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
FOCC007839-PA	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
FOCC001514-PA	13	KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-5122	"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis"
FOCC004253-PA	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
FOCC015808-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
FOCC015363-PA	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
FOCC007754-PA	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
FOCC011160-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
FOCC002102-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC008867-PA	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
FOCC005136-PA	5	Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-8856828	"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Clathrin-mediated endocytosis"
FOCC015254-PA	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism"
FOCC002750-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC007823-PA	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802946	"Human papillomavirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"PI3K-Akt signaling pathway";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"Thermogenesis";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"Signaling by high-kinase activity BRAF mutants";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling by moderate kinase activity BRAF mutants"
FOCC010807-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC016365-PA	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
FOCC001168-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
FOCC016971-PA	7	KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;Reactome: R-HSA-5628897	"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes"
FOCC011199-PA	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
FOCC003795-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC016797-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
FOCC004889-PA	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
FOCC005884-PA	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
FOCC015074-PA	4	MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
FOCC013263-PA	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
FOCC004667-PA	1	Reactome: R-HSA-1632852	"Macroautophagy"
FOCC003599-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC008386-PA	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
FOCC000563-PA	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
FOCC014718-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
FOCC016322-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC006741-PA	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC001917-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
FOCC016213-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC013581-PA	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
FOCC001673-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC002631-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC017791-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC014850-PA	7	KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484	"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)"
FOCC015674-PA	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
FOCC001081-PA	5	KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892	"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
FOCC000143-PA	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
FOCC009046-PA	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
FOCC005636-PA	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)"
FOCC013009-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
FOCC011311-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC001117-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC004721-PA	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
FOCC005776-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC007868-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC017283-PA	5	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis"
FOCC014562-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
FOCC003120-PA	56	Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974	"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway"
FOCC002511-PA	12	MetaCyc: PWY-5132;MetaCyc: PWY-7118;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1	"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes"
FOCC000634-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC009536-PA	10	Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702	"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands"
FOCC005833-PA	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
FOCC007900-PA	7	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-7791	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III"
FOCC017404-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC014291-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC008409-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC001522-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC002404-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
FOCC013971-PA	26	Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736	"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"Cilium Assembly";"Gap junction assembly";"Kinesins";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors"
FOCC009466-PA	17	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-6608;KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-7179;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6620;MetaCyc: PWY-5532	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)"
FOCC013397-PA	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
FOCC004872-PA	17	Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-1433557;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75035;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-69601;Reactome: R-HSA-176187;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69473	"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"Signaling by SCF-KIT";"Human papillomavirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of ATR in response to replication stress";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"G2/M DNA damage checkpoint"
FOCC017043-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC004904-PA	13	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5687128	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"EPHB-mediated forward signaling";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Human papillomavirus infection";"MAPK6/MAPK4 signaling"
FOCC002509-PA	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC013837-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC001874-PA	3	MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57	"Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism"
FOCC002998-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC006480-PA	1	Reactome: R-HSA-8876725	"Protein methylation"
FOCC009321-PA	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
FOCC004335-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
FOCC012605-PA	14	Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK"
FOCC012350-PA	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
FOCC007826-PA	6	Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination"
FOCC004489-PA	2	KEGG: 00040+5.3.1.5;KEGG: 00051+5.3.1.5	"Pentose and glucuronate interconversions";"Fructose and mannose metabolism"
FOCC000397-PA	7	MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis"
FOCC002615-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
FOCC007772-PA	3	Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760	"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation"
FOCC017533-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
FOCC000140-PA	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes"
FOCC005381-PA	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC001848-PA	5	Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
FOCC002628-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC014793-PA	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
FOCC015480-PA	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
FOCC017464-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC001781-PA	6	Reactome: R-HSA-1250196;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"SHC1 events in ERBB2 signaling";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
FOCC008591-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC007021-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC012864-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC001070-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC003212-PA	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC017729-PA	1	Reactome: R-HSA-6803529	"FGFR2 alternative splicing"
FOCC012145-PA	5	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
FOCC008635-PA	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
FOCC011313-PA	10	MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061	"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I"
FOCC007068-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
FOCC003247-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC014097-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC016162-PA	5	Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
FOCC013058-PA	19	MetaCyc: PWY-5172;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-5392;Reactome: R-HSA-6798695;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-5690	"Acetyl-coa biosynthesis III (from citrate)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Neutrophil degranulation";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)"
FOCC012997-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC000004-PA	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
FOCC017225-PA	19	KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00020+2.3.1.61;MetaCyc: PWY-6969;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5690;Reactome: R-HSA-71064;Reactome: R-HSA-389661;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5537;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5084;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5	"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Lysine degradation";"TCA cycle II (plants and fungi)";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Tryptophan metabolism";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism"
FOCC015337-PA	6	Reactome: R-HSA-5628897;Reactome: R-HSA-2408550;KEGG: 00480+1.8.1.7;Reactome: R-HSA-3299685;Reactome: R-HSA-499943;MetaCyc: PWY-4081	"TP53 Regulates Metabolic Genes";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"Interconversion of nucleotide di- and triphosphates";"Glutathione-peroxide redox reactions"
FOCC016880-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
FOCC016700-PA	6	Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-389661;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105	"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate metabolism and glycine degradation";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis"
FOCC001748-PA	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
FOCC016981-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC004578-PA	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
FOCC015920-PA	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism"
FOCC013087-PA	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
FOCC013427-PA	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469	"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis"
FOCC016030-PA	56	Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-180534	"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of AXIN";"G2/M Checkpoints";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4"
FOCC004993-PA	6	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1"
FOCC014356-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC005711-PA	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
FOCC006309-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC001520-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC016117-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC008786-PA	5	KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7919	"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)"
FOCC011064-PA	6	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1"
FOCC002904-PA	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
FOCC017707-PA	1	Reactome: R-HSA-977443	"GABA receptor activation"
FOCC003955-PA	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
FOCC002851-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
FOCC002636-PA	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
FOCC008699-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC005682-PA	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
FOCC014954-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC006675-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC004414-PA	5	Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
FOCC012937-PA	10	Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Inhibition of membrane repair"
FOCC017452-PA	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
FOCC000881-PA	16	MetaCyc: PWY-5749;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.5;KEGG: 00640+6.2.1.4;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5538	"Itaconate degradation";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI"
FOCC002328-PA	5	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Neutrophil degranulation"
FOCC007402-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
FOCC000842-PA	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection"
FOCC006903-PA	5	MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4;Reactome: R-HSA-6798695;MetaCyc: PWY-8060;Reactome: R-HSA-71336	"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway"
FOCC003878-PA	17	Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-200425;MetaCyc: PWY-6679;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5743	"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carnitine metabolism";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation";"Propanoate metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle"
FOCC000112-PA	2	Reactome: R-HSA-8934593;Reactome: R-HSA-69231	"Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1"
FOCC007681-PA	1	Reactome: R-HSA-8963684	"Tyrosine catabolism"
FOCC013429-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC002244-PA	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
FOCC006246-PA	11	Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-5689880;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Ub-specific processing proteases";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
FOCC000037-PA	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
FOCC007501-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC015115-PA	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
FOCC000023-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC016718-PA	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
FOCC004874-PA	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
FOCC016048-PA	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
FOCC008820-PA	19	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-3214858;Reactome: R-HSA-192823;Reactome: R-HSA-8876725;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"RMTs methylate histone arginines";"Viral mRNA Translation";"Protein methylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC017099-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC017375-PA	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
FOCC015952-PA	5	Reactome: R-HSA-171319;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-6790901;Reactome: R-HSA-5419276	"Telomere Extension By Telomerase";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"rRNA modification in the nucleus and cytosol";"Mitochondrial translation termination"
FOCC002447-PA	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
FOCC002412-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC015583-PA	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
FOCC011432-PA	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
FOCC013327-PA	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
FOCC016767-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC005773-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
FOCC000451-PA	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
FOCC011430-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC015284-PA	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
FOCC004289-PA	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
FOCC012630-PA	16	Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-1257604;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-194840	"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"RET signaling";"PIP3 activates AKT signaling";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Rho GTPase cycle"
FOCC015970-PA	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
FOCC006282-PA	5	MetaCyc: PWY-7282;Reactome: R-HSA-6798695;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
FOCC011509-PA	7	MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7	"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis"
FOCC000426-PA	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
FOCC014745-PA	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
FOCC002635-PA	13	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC004947-PA	33	Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3108214	"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins"
FOCC009244-PA	5	Reactome: R-HSA-9033241;Reactome: R-HSA-389887;Reactome: R-HSA-193368;Reactome: R-HSA-390247;Reactome: R-HSA-2046106	"Peroxisomal protein import";"Beta-oxidation of pristanoyl-CoA";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Beta-oxidation of very long chain fatty acids";"alpha-linolenic acid (ALA) metabolism"
FOCC006134-PA	4	KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
FOCC014415-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
FOCC008853-PA	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
FOCC016906-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
FOCC015754-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
FOCC011998-PA	6	KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723	"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Rubisco shunt"
FOCC016722-PA	8	KEGG: 00030+5.3.1.6;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996;Reactome: R-HSA-6791461;MetaCyc: PWY-1861;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P";"RPIA deficiency: failed conversion of RU5P to R5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway"
FOCC006048-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
FOCC001705-PA	8	KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980	"Oxidative phosphorylation";"Photosynthesis";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis"
FOCC007179-PA	10	KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-975634;MetaCyc: PWY-7849;MetaCyc: PWY-5691	"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Neutrophil degranulation";"Retinoid metabolism and transport";"Urate conversion to allantoin III";"Urate conversion to allantoin I"
FOCC006698-PA	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
FOCC001764-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
FOCC008933-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC016296-PA	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC017546-PA	8	Reactome: R-HSA-380284;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
FOCC003722-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
FOCC015010-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
FOCC007833-PA	57	Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Neddylation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport"
FOCC001077-PA	8	KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980	"Oxidative phosphorylation";"Photosynthesis";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis"
FOCC009501-PA	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
FOCC010743-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC002530-PA	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
FOCC003056-PA	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
FOCC004003-PA	7	KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;MetaCyc: PWY-5084	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA"
FOCC011508-PA	13	MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857	"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"CS/DS degradation";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation"
FOCC006524-PA	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC008000-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC013168-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC009392-PA	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
FOCC006663-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
FOCC007705-PA	10	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
FOCC009495-PA	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
FOCC002474-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
FOCC000639-PA	1	Reactome: R-HSA-420029	"Tight junction interactions"
FOCC015773-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
FOCC008612-PA	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7007;Reactome: R-HSA-9033241	"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import"
FOCC007932-PA	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
FOCC003582-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
FOCC008821-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC008995-PA	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
FOCC003438-PA	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
FOCC002717-PA	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
FOCC002178-PA	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC003331-PA	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC000851-PA	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
FOCC004626-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC001170-PB	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2	"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling";"T cell receptor signaling pathway"
FOCC006268-PA	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
FOCC008114-PA	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
FOCC004140-PA	17	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation"
FOCC015534-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
FOCC014055-PA	4	KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247	"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids"
FOCC000284-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
FOCC000724-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC007915-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC004654-PA	1	Reactome: R-HSA-1483101	"Synthesis of PS"
FOCC011324-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC003411-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
FOCC005356-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
FOCC004783-PA	1	Reactome: R-HSA-71384	"Ethanol oxidation"
FOCC016049-PA	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC008403-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
FOCC017763-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC014995-PA	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
FOCC015153-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC002909-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
FOCC008365-PA	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
FOCC013319-PA	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
FOCC004115-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC011542-PA	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway"
FOCC017463-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC014997-PA	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
FOCC000403-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs"
FOCC004078-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
FOCC008424-PA	11	Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408	"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation"
FOCC012806-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC004878-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC003166-PA	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
FOCC009231-PA	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC017775-PA	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
FOCC001900-PA	3	Reactome: R-HSA-6799198;Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Complex I biogenesis";"Mitochondrial protein import";"Respiratory electron transport"
FOCC013098-PA	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC010855-PA	5	Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148	"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC009107-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC012836-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC000464-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC007094-PA	5	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-165159	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTOR signalling"
FOCC004285-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC015183-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC005048-PA	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
FOCC015535-PA	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
FOCC004501-PA	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
FOCC014800-PA	6	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-111367	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
FOCC004095-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC015621-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC005704-PA	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
FOCC003841-PA	6	Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling"
FOCC006669-PA	5	Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233	"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway"
FOCC008826-PA	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
FOCC003238-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC004427-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC006656-PA	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
FOCC017652-PA	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
FOCC001462-PA	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
FOCC011874-PA	5	Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357	"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling"
FOCC009262-PA	5	KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.1.25;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-5340	"Purine metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation"
FOCC012058-PA	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
FOCC004717-PA	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
FOCC002362-PA	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC001656-PA	26	Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-9619483	"Kinesins";"Gap junction assembly";"Cilium Assembly";"MHC class II antigen presentation";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs"
FOCC006233-PA	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
FOCC013333-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC016220-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC012170-PA	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
FOCC013737-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-5678771;Reactome: R-HSA-382556	"PPARA activates gene expression";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"ABC-family proteins mediated transport"
FOCC014492-PA	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC017179-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC007650-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC005626-PA	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
FOCC008674-PA	18	MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925	"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Synthesis of PA";"Acyl chain remodelling of PG"
FOCC006368-PA	13	Reactome: R-HSA-6798695;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-8876725;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5689896;Reactome: R-HSA-5678895;Reactome: R-HSA-110320	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"Aggrephagy";"Josephin domain DUBs";"Protein methylation";"HSF1 activation";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ovarian tumor domain proteases";"Defective CFTR causes cystic fibrosis";"Translesion Synthesis by POLH"
FOCC004264-PA	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.142;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.142	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis"
FOCC002403-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
FOCC012602-PA	6	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-5632684	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state"
FOCC015948-PA	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
FOCC001532-PA	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
FOCC001955-PA	13	MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II"
FOCC004884-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC003629-PA	3	Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
FOCC007930-PA	56	Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-75815	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Degradation of AXIN";"G2/M Checkpoints";"Ub-specific processing proteases";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D"
FOCC005715-PA	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
FOCC009516-PA	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Neddylation"
FOCC005962-PA	12	Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-72662	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
FOCC011333-PA	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
FOCC005161-PA	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
FOCC016451-PA	10	Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-201688	"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Synthesis of PC";"WNT mediated activation of DVL"
FOCC003169-PA	11	Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-6783310;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-111464	"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"Fanconi Anemia Pathway";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
FOCC013343-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC012179-PA	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
FOCC008935-PA	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
FOCC012272-PA	13	MetaCyc: PWY-7198;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7220	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II"
FOCC004680-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
FOCC012035-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC003020-PA	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
FOCC001288-PA	24	Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736	"MHC class II antigen presentation";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Gap junction assembly";"Kinesins";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors"
FOCC012087-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC001555-PA	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping"
FOCC006421-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC016312-PA	13	MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-7736;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-7182	"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I"
FOCC005684-PA	13	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC013752-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
FOCC008710-PA	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events"
FOCC003634-PA	10	Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167161	"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation"
FOCC008923-PA	24	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Gap junction assembly";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport"
FOCC008977-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
FOCC010851-PA	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC010837-PA	8	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-174430	"DNA replication initiation";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Telomere C-strand synthesis initiation"
FOCC014843-PA	14	KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00250+4.3.1.1;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-6728	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Alanine, aspartate and glutamate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle"
FOCC018012-PA	8	Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676	"PKA activation in glucagon signalling";"PKA activation";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
FOCC007256-PA	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
FOCC013665-PA	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681	"Activation of SMO";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions"
FOCC014139-PA	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
FOCC012182-PA	6	Reactome: R-HSA-3878781;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-622;Reactome: R-HSA-3322077	"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen synthesis"
FOCC004953-PA	52	Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-76061;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-167158;Reactome: R-HSA-1834949;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-73980;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-6782135	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER"
FOCC002464-PA	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
FOCC004025-PA	9	Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-975634	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport"
FOCC016115-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
FOCC015614-PA	9	KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52	"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series"
FOCC000159-PA	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
FOCC013974-PA	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
FOCC003366-PA	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
FOCC017961-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC001830-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC002160-PA	29	Reactome: R-HSA-5693616;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-110320	"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Translesion Synthesis by POLH"
FOCC015991-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC001477-PA	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
FOCC015508-PA	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
FOCC014865-PA	5	KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;MetaCyc: PWY-6614;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3	"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate biosynthesis"
FOCC002940-PA	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
FOCC008074-PA	15	Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-112382	"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex"
FOCC016882-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC004279-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
FOCC001296-PA	7	Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-6804114	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
FOCC002437-PA	6	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-622	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch biosynthesis"
FOCC002241-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC016766-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC007356-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC012413-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC000224-PA	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
FOCC002979-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC004920-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC008537-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC017026-PA	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
FOCC006604-PA	1	Reactome: R-HSA-3295583	"TRP channels"
FOCC011709-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC007046-PA	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
FOCC006896-PA	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
FOCC009566-PA	13	MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9	"Folate transformations II (plants)";"Folate polyglutamylation";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Metabolism of folate and pterines";"One carbon pool by folate"
FOCC011111-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC013251-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC000916-PA	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
FOCC005575-PA	58	Reactome: R-HSA-77348;MetaCyc: PWY-7007;KEGG: 00281+4.2.1.17;KEGG: 00720+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00310+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-5789;Reactome: R-HSA-77288;MetaCyc: PWY-6863;KEGG: 00280+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;Reactome: R-HSA-77285;KEGG: 00592+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5177;KEGG: 00280+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-7401;KEGG: 00650+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-6435;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-5109;Reactome: R-HSA-77350;MetaCyc: PWY-7094;MetaCyc: PWY-7216;MetaCyc: PWY-5136;Reactome: R-HSA-77310;MetaCyc: PWY-6944;MetaCyc: PWY-7656;MetaCyc: PWY-6946;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00380+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7779;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-7778;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00930+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;MetaCyc: PWY-6945	"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Methyl ketone biosynthesis (engineered)";"Geraniol degradation";"Carbon fixation pathways in prokaryotes";"Acyl chain remodeling of CL";"Lysine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Benzoate degradation";"Carbon fixation pathways in prokaryotes";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"3-hydroxypropanoate/4-hydroxybutanate cycle";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Pyruvate fermentation to hexanol (engineered)";"Valine, leucine and isoleucine degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"alpha-Linolenic acid metabolism";"Caprolactam degradation";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Glutaryl-coa degradation";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Propanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Butanoate metabolism";"Aminobenzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid elongation";"Fermentation to 2-methylbutanoate";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fatty acid salvage";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Tryptophan metabolism";"Limonene and pinene degradation";"Tryptophan metabolism";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl tert-butyl ether degradation";"Butanoate metabolism";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"Phenylalanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"2-methylpropene degradation";"Fatty acid degradation";"Caprolactam degradation";"Toluene degradation";"Fatty acid elongation";"Benzoate degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)"
FOCC014135-PA	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC002406-PA	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
FOCC010999-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC014304-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
FOCC012530-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC000581-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC013818-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC014048-PA	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
FOCC007126-PA	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
FOCC001390-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC009148-PA	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis"
FOCC014528-PA	52	Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-76061;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-73980;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167238	"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation"
FOCC012132-PA	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
FOCC009572-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC003398-PA	11	Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332	"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
FOCC009560-PA	8	MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;MetaCyc: PWY-5740;MetaCyc: PWY-66	"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)"
FOCC013899-PA	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
FOCC001674-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC009327-PA	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
FOCC008367-PA	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
FOCC008264-PA	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
FOCC008653-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC009574-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC014329-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
FOCC007064-PA	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
FOCC006955-PA	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
FOCC007131-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC001366-PA	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
FOCC000577-PA	7	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins"
FOCC002997-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
FOCC017069-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC016068-PA	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
FOCC004831-PA	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
FOCC017559-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC006308-PA	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
FOCC013809-PA	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
FOCC013381-PA	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
FOCC011205-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC014382-PA	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
FOCC001548-PA	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
FOCC006150-PA	18	MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166	"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Synthesis of PA"
FOCC000983-PA	1	Reactome: R-HSA-3295583	"TRP channels"
FOCC005947-PA	9	Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1	"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection"
FOCC007114-PA	7	Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813	"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids"
FOCC014713-PA	3	KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3	"Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism"
FOCC006644-PA	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
FOCC006756-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC014422-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC002924-PA	8	MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
FOCC015546-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC008417-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC012065-PA	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
FOCC012660-PA	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
FOCC001663-PA	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
FOCC002982-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC012324-PA	5	Reactome: R-HSA-196843;MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-5523	"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)"
FOCC016961-PA	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
FOCC001459-PA	10	MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757	"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate";"Metabolism of folate and pterines"
FOCC002745-PA	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
FOCC005553-PA	16	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
FOCC008606-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
FOCC008322-PA	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
FOCC012129-PA	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
FOCC000523-PA	13	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression"
FOCC015584-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
FOCC004575-PA	6	KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation"
FOCC005829-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC012548-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC015582-PA	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
FOCC006102-PA	2	KEGG: 00900+2.7.7.60;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
FOCC006000-PA	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
FOCC010880-PA	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
FOCC009639-PA	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
FOCC003910-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
FOCC017236-PA	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
FOCC011084-PA	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC012352-PA	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
FOCC001692-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC015376-PA	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
FOCC008490-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC010905-PA	10	Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange"
FOCC016508-PA	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
FOCC011657-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC015532-PA	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
FOCC007361-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC008768-PA	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
FOCC015333-PA	2	KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19	"Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis"
FOCC007061-PA	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
FOCC005915-PC	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC006107-PA	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
FOCC001172-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC015043-PA	13	Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825	"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis"
FOCC005344-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC013066-PA	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
FOCC015800-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC004007-PA	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC017098-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC012127-PA	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
FOCC007054-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC008828-PA	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
FOCC013448-PA	4	KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
FOCC003207-PA	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
FOCC006131-PA	13	KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-5690	"Propanoate metabolism";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)"
FOCC011371-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC012150-PA	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
FOCC017612-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC008882-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC007897-PA	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation"
FOCC011288-PA	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
FOCC002254-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC002613-PA	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
FOCC013124-PA	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC010708-PA	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
FOCC012355-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
FOCC001111-PA	5	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
FOCC005372-PA	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-6784531	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus"
FOCC010942-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC012003-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
FOCC002284-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
FOCC002917-PA	4	KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
FOCC003403-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
FOCC016979-PA	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
FOCC001734-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC005260-PA	16	Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-167287;Reactome: R-HSA-167238	"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Neddylation";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
FOCC012607-PA	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling"
FOCC000262-PA	13	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-4420097	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"EPHA-mediated growth cone collapse";"G alpha (12/13) signalling events";"Human papillomavirus infection";"mTOR signaling pathway";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway"
FOCC014859-PA	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-947581	"Aminoacyl-tRNA biosynthesis";"Molybdenum cofactor biosynthesis"
FOCC000547-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
FOCC012147-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
FOCC016980-PA	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
FOCC016165-PA	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
FOCC016730-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC006274-PA	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC013205-PA	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
FOCC016531-PA	4	Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-6798695;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Cargo concentration in the ER";"Neutrophil degranulation";"COPII-mediated vesicle transport"
FOCC014950-PA	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
FOCC003288-PA	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
FOCC001939-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC003268-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC008938-PA	13	KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883	"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II"
FOCC012371-PA	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
FOCC003414-PA	5	Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928	"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
FOCC003449-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC013049-PA	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
FOCC005999-PA	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
FOCC008093-PA	27	Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-1169408	"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism"
FOCC002422-PA	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
FOCC008539-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC009528-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
FOCC017373-PA	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
FOCC006347-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC012771-PA	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
FOCC008293-PA	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
FOCC000893-PA	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
FOCC011572-PA	5	Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108	"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
FOCC001845-PA	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
FOCC012325-PA	5	Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897	"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes"
FOCC011297-PA	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
FOCC003217-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC004635-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
FOCC004982-PA	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
FOCC002655-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC004577-PA	27	Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5619107	"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
FOCC015588-PA	3	Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310	"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway"
FOCC001423-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC000309-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC003676-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
FOCC000200-PA	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
FOCC004380-PA	5	Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7185	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I"
FOCC009209-PA	4	Reactome: R-HSA-379716;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557	"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis"
FOCC007944-PA	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185	"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I"
FOCC007406-PA	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
FOCC013096-PA	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
FOCC002575-PA	10	Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-913709;MetaCyc: PWY-7661;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;Reactome: R-HSA-4719360	"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation of mucins";"Protein N-glycosylation (Haloferax volcanii)";"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
FOCC013541-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC012066-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC012041-PA	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
FOCC005282-PA	24	Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736	"MHC class II antigen presentation";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Gap junction assembly";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors"
FOCC009395-PA	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
FOCC002847-PA	6	Reactome: R-HSA-983168;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity"
FOCC000638-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC007221-PA	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
FOCC010879-PA	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
FOCC004994-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
FOCC002648-PA	33	Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-3108214	"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins"
FOCC000106-PA	29	Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation"
FOCC013007-PA	8	Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-6791461;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;KEGG: 00030+5.3.1.6;MetaCyc: PWY-5723	"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Rubisco shunt"
FOCC007582-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
FOCC007369-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC011164-PA	9	Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome"
FOCC000226-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
FOCC016772-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC006506-PA	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
FOCC014487-PA	15	MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-7383	"Rubisco shunt";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)"
FOCC000921-PA	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
FOCC017983-PA	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
FOCC014475-PA	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
FOCC003481-PA	9	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint"
FOCC009489-PA	2	Reactome: R-HSA-2173796;Reactome: R-HSA-6785807	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interleukin-4 and Interleukin-13 signaling"
FOCC011807-PA	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
FOCC016294-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC005309-PA	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
FOCC015604-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC003197-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC012717-PA	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
FOCC015823-PA	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
FOCC017877-PA	31	MetaCyc: PWY-7663;MetaCyc: PWY-5994;MetaCyc: PWYG-321;MetaCyc: PWY-5971;MetaCyc: PWY-8049;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-8012;MetaCyc: PWY-4381;MetaCyc: PWY-7858;MetaCyc: PWY-5989;Reactome: R-HSA-75105;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-6799;Reactome: R-HSA-163765	"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Fatty acid biosynthesis";"Bryostatin biosynthesis";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"ChREBP activates metabolic gene expression"
FOCC017383-PA	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
FOCC008569-PA	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
FOCC014491-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC008499-PA	1	Reactome: R-HSA-8949613	"Cristae formation"
FOCC004539-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC010765-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC008585-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC017641-PA	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism"
FOCC016716-PA	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
FOCC010776-PA	7	Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-380972	"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK"
FOCC006850-PA	4	Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport"
FOCC000809-PA	8	MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
FOCC001394-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC011287-PA	8	Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
FOCC015443-PA	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
FOCC015894-PA	57	Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-450408	"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Neddylation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
FOCC012068-PA	6	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
FOCC013842-PA	9	Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
FOCC002382-PA	10	KEGG: 00010+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1	"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Inositol phosphate metabolism";"Fructose and mannose metabolism"
FOCC014926-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC015821-PA	2	KEGG: 00900+1.1.1.267;MetaCyc: PWY-7560	"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
FOCC003506-PB	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
FOCC007756-PA	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
FOCC011536-PA	11	Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
FOCC007565-PA	5	Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558	"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
FOCC002301-PA	2	Reactome: R-HSA-156581;Reactome: R-HSA-5689880	"Methylation";"Ub-specific processing proteases"
FOCC000491-PA	6	Reactome: R-HSA-2892245;Reactome: R-HSA-452723;Reactome: R-HSA-6785807;Reactome: R-HSA-3769402;Reactome: R-HSA-8986944;Reactome: R-HSA-2892247	"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation";"Transcriptional regulation of pluripotent stem cells";"Interleukin-4 and Interleukin-13 signaling";"Deactivation of the beta-catenin transactivating complex";"Transcriptional Regulation by MECP2";"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"
FOCC002954-PA	17	Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606	"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
FOCC013660-PA	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
FOCC003590-PA	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
FOCC001897-PA	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
FOCC007587-PA	12	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-141444	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC014727-PA	6	Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;MetaCyc: PWY-7980	"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Cristae formation";"ATP biosynthesis"
FOCC014849-PA	4	Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation"
FOCC014277-PA	6	Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs"
FOCC003739-PA	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
FOCC001022-PA	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
FOCC002552-PA	2	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
FOCC017194-PA	1	Reactome: R-HSA-71064	"Lysine catabolism"
FOCC006729-PA	1	Reactome: R-HSA-611105	"Respiratory electron transport"
FOCC011406-PA	14	KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;Reactome: R-HSA-975634	"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport"
FOCC005352-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
FOCC002941-PA	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
FOCC008609-PA	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
FOCC003410-PA	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
FOCC000929-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC004637-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC018008-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC007317-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC014708-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
FOCC005426-PA	12	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
FOCC017531-PA	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
FOCC011107-PA	56	Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-68827	"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex"
FOCC003992-PA	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805;Reactome: R-HSA-71737	"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis"
FOCC007976-PA	7	MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11	"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
FOCC008759-PA	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
FOCC001731-PA	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
FOCC006662-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC002889-PA	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
FOCC009232-PA	5	KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
FOCC012840-PA	3	KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
FOCC009106-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC003174-PA	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
FOCC000247-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC013076-PA	22	Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358752	"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated"
FOCC001626-PA	1	Reactome: R-HSA-189200	"Cellular hexose transport"
FOCC009423-PA	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
FOCC011734-PA	5	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
FOCC007939-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC004808-PA	4	Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852	"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy"
FOCC014768-PA	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
FOCC014992-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC001409-PA	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
FOCC000476-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC005686-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC009649-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC017022-PA	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
FOCC003763-PA	15	Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176412	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C"
FOCC014748-PA	2	MetaCyc: PWY-6700;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
FOCC005533-PB	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC011028-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC011770-PA	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
FOCC000277-PA	7	MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-6737	"Glycogen degradation II";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Neutrophil degranulation";"Starch degradation V"
FOCC002839-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC008393-PA	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
FOCC007274-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC014707-PA	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
FOCC014477-PA	2	MetaCyc: PWY-6308;Reactome: R-HSA-114608	"L-cysteine biosynthesis II (tRNA-dependent)";"Platelet degranulation"
FOCC013700-PA	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
FOCC004944-PA	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
FOCC006991-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC016044-PA	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
FOCC012513-PA	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
FOCC003128-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC006235-PA	4	MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14	"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism"
FOCC009123-PA	4	Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862	"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)"
FOCC009591-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC017246-PA	4	MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062	"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol"
FOCC008395-PA	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription"
FOCC009109-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC012914-PA	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
FOCC011763-PA	8	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"T cell receptor signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection"
FOCC011906-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
FOCC005245-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC005883-PA	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
FOCC013674-PA	16	Reactome: R-HSA-5603037;Reactome: R-HSA-1810476;Reactome: R-HSA-166058;Reactome: R-HSA-975110;Reactome: R-HSA-6811558;Reactome: R-HSA-975155;Reactome: R-HSA-975138;Reactome: R-HSA-5602680;Reactome: R-HSA-5603041;Reactome: R-HSA-209543;Reactome: R-HSA-1257604;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-3134963;Reactome: R-HSA-975871;Reactome: R-HSA-5602498	"IRAK4 deficiency (TLR5)";"RIP-mediated NFkB activation via ZBP1";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"PIP3 activates AKT signaling";"ER-Phagosome pathway";"Interleukin-1 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)"
FOCC007494-PA	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
FOCC000304-PA	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
FOCC005214-PA	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC006654-PA	7	KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
FOCC017990-PA	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
FOCC000111-PA	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
FOCC005592-PA	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
FOCC002416-PA	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
FOCC006681-PA	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
FOCC001332-PA	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
FOCC009541-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC003184-PA	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
FOCC005663-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC006634-PA	18	KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7220;Reactome: R-HSA-5624138;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6	"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Trafficking of myristoylated proteins to the cilium";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes"
FOCC016711-PA	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
FOCC000644-PA	7	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6798695	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation"
FOCC009207-PA	2	KEGG: 00240+2.7.4.25;MetaCyc: PWY-7205	"Pyrimidine metabolism";"CMP phosphorylation"
FOCC004277-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC013322-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC008443-PA	18	Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803	"Acyl chain remodelling of PG";"Synthesis of PA";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing"
FOCC006249-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC004630-PA	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
FOCC000503-PA	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
FOCC003506-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
FOCC003857-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC014533-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
FOCC008727-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC008257-PA	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
FOCC016617-PA	24	Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736	"Cilium Assembly";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Gap junction assembly";"Kinesins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors"
FOCC002409-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC014717-PA	3	KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3	"Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism"
FOCC007116-PA	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
FOCC011206-PA	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
FOCC015950-PA	1	Reactome: R-HSA-8849175	"Threonine catabolism"
FOCC015689-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
FOCC006419-PA	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
FOCC007074-PA	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
FOCC015900-PA	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
FOCC001047-PA	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
FOCC001649-PA	4	Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Arginine and proline metabolism"
FOCC005957-PA	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1"
FOCC002383-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC002783-PA	7	KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
FOCC000080-PA	2	Reactome: R-HSA-2160916;Reactome: R-HSA-8854518	"Hyaluronan uptake and degradation";"AURKA Activation by TPX2"
FOCC003300-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC014292-PA	9	KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18	"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450"
FOCC004709-PA	3	Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC003888-PA	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
FOCC005157-PA	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
FOCC016143-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC016263-PA	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC007956-PA	4	Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-983168	"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC014234-PA	12	KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5132;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Colupulone and cohumulone biosynthesis";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism"
FOCC017416-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC005815-PA	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
FOCC007422-PA	7	Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
FOCC000936-PA	3	Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate"
FOCC006499-PA	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation"
FOCC004507-PA	8	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Activation of RAC1";"Human cytomegalovirus infection"
FOCC016087-PA	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
FOCC002720-PA	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
FOCC015829-PA	6	KEGG: 00550+2.4.1.129;MetaCyc: PWY-6385;MetaCyc: PWY-6471;MetaCyc: PWY-6470;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.129+3.4.16.4	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis"
FOCC013291-PA	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
FOCC011419-PA	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Caprolactam degradation"
FOCC004849-PA	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
FOCC002519-PA	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
FOCC006049-PA	8	Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
FOCC018017-PA	11	Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418594	"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (i) signalling events"
FOCC005920-PA	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
FOCC000794-PA	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
FOCC011870-PA	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC007597-PA	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
FOCC003126-PA	8	Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-922	"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I"
FOCC004862-PA	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
FOCC001364-PA	1	Reactome: R-HSA-70350	"Fructose catabolism"
FOCC007777-PA	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
FOCC013573-PA	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
FOCC004937-PA	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
FOCC001578-PA	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
FOCC016798-PA	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
FOCC011855-PA	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
FOCC008370-PA	8	MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826;MetaCyc: PWY-7179	"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I"
FOCC003697-PA	26	Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276	"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Kinesins";"MHC class II antigen presentation";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint"
FOCC002634-PA	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC008488-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC009427-PA	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
FOCC002381-PA	14	Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
FOCC003785-PA	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
FOCC003492-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC000043-PA	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
FOCC013984-PA	1	Reactome: R-HSA-156588	"Glucuronidation"
FOCC005538-PA	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
FOCC001138-PA	33	Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-69656;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-69202	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Cyclin E associated events during G1/S transition"
FOCC002928-PA	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
FOCC007088-PA	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
FOCC000696-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
FOCC013980-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC003973-PA	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
FOCC006919-PA	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
FOCC005387-PA	9	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER"
FOCC001630-PA	13	Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
FOCC001844-PA	7	Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-72702	"Deadenylation of mRNA";"Translation initiation complex formation";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition"
FOCC002823-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC005235-PA	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
FOCC010838-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC000440-PA	4	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531;Reactome: R-HSA-77289	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus";"Mitochondrial Fatty Acid Beta-Oxidation"
FOCC014066-PA	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
FOCC000314-PA	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
FOCC001145-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
FOCC005678-PA	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
FOCC004815-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC017553-PA	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
FOCC016366-PA	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
FOCC002038-PA	56	Reactome: R-HSA-382556;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-450408	"ABC-family proteins mediated transport";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"G2/M Checkpoints";"Degradation of AXIN";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
FOCC000975-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC012506-PA	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
FOCC006990-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC004305-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC008651-PA	3	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
FOCC004334-PA	14	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
FOCC009200-PA	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
FOCC011782-PA	7	KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514	"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane"
FOCC009254-PA	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-1799339	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"SRP-dependent cotranslational protein targeting to membrane"
FOCC014864-PA	7	KEGG: 00240+6.3.5.5;MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-5686	"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"UMP biosynthesis III";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I"
FOCC013387-PA	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
FOCC011167-PA	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
FOCC014737-PA	6	Reactome: R-HSA-196783;MetaCyc: PWY-7851;KEGG: 00983+3.6.1.23;KEGG: 00770+4.1.1.36+6.3.2.5;KEGG: 00240+3.6.1.23;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)";"Drug metabolism - other enzymes";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis"
FOCC003803-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC013827-PA	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
FOCC009273-PA	24	KEGG: 00525+4.2.1.46;MetaCyc: PWY-7413;MetaCyc: PWY-6808;MetaCyc: PWY-7414;KEGG: 00521+4.2.1.46;MetaCyc: PWY-7688;KEGG: 00523+4.2.1.46;MetaCyc: PWY-7312;MetaCyc: PWY-7814;KEGG: 00525+2.7.7.24;MetaCyc: PWY-7316;MetaCyc: PWY-6976;MetaCyc: PWY-7440;MetaCyc: PWY-7315;MetaCyc: PWY-6953;MetaCyc: PWY-7318;MetaCyc: PWY-6973;KEGG: 00521+2.7.7.24;MetaCyc: PWY-6942;MetaCyc: PWY-7657;MetaCyc: PWY-7301;KEGG: 00523+2.7.7.24;MetaCyc: PWY-6974;MetaCyc: PWY-7104	"Acarbose and validamycin biosynthesis";"Dtdp-6-deoxy-alpha-d-allose biosynthesis";"Dtdp-d-forosamine biosynthesis";"Dtdp-alpha-d-mycaminose biosynthesis";"Streptomycin biosynthesis";"Dtdp-d-ravidosamine and dTDP-4-acetyl-D-ravidosamine biosynthesis";"Polyketide sugar unit biosynthesis";"Dtdp-d-beta-fucofuranose biosynthesis";"Dtdp-l-daunosamine biosynthesis";"Acarbose and validamycin biosynthesis";"Dtdp-n-acetylviosamine biosynthesis";"Dtdp-l-mycarose biosynthesis";"Dtdp-beta-l-4-epi-vancosamine biosynthesis";"Dtdp-n-acetylthomosamine biosynthesis";"Dtdp-3-acetamido-alpha-d-fucose biosynthesis";"Dtdp-3-acetamido-3,6-dideoxy-alpha-d-glucose biosynthesis";"Dtdp-d-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis";"Streptomycin biosynthesis";"Dtdp-d-desosamine biosynthesis";"Dtdp-beta-l-digitoxose biosynthesis";"Dtdp-4-o-demethyl-beta-l-noviose biosynthesis";"Polyketide sugar unit biosynthesis";"Dtdp-l-olivose biosynthesis";"Dtdp-l-megosamine biosynthesis"
FOCC013269-PA	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
FOCC017281-PA	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
FOCC012022-PA	4	MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism"
FOCC015769-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC009166-PA	4	Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26	"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
FOCC009363-PA	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
FOCC010778-PA	8	Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207	"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases"
FOCC001267-PA	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
FOCC015822-PA	2	Reactome: R-HSA-8964539;KEGG: 00240+2.7.4.22	"Glutamate and glutamine metabolism";"Pyrimidine metabolism"
FOCC011423-PA	10	MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-7003;Reactome: R-HSA-70263;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-1042	"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)"
FOCC005674-PA	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC005209-PA	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706	"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling"
FOCC007442-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC008642-PA	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
FOCC014207-PA	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
FOCC007166-PA	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway"
FOCC002486-PA	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
FOCC015977-PA	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
FOCC010933-PA	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
FOCC014330-PA	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
FOCC001395-PA	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
FOCC010725-PA	16	MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-1622;Reactome: R-HSA-70171;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-6886;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis";"Rubisco shunt";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycerol degradation to butanol"
FOCC005984-PA	5	Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
FOCC000612-PA	8	Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
FOCC007280-PA	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression"
FOCC006981-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
FOCC003037-PA	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
FOCC015843-PA	7	MetaCyc: PWY-7396;Reactome: R-HSA-71403;KEGG: 00620+2.3.3.13;KEGG: 00290+1.1.1.85;KEGG: 00290+2.3.3.13;MetaCyc: PWY-6871;KEGG: 00660+1.1.1.85	"Butanol and isobutanol biosynthesis (engineered)";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Valine, leucine and isoleucine biosynthesis";"Valine, leucine and isoleucine biosynthesis";"3-methylbutanol biosynthesis (engineered)";"C5-Branched dibasic acid metabolism"
FOCC011681-PA	4	Reactome: R-HSA-379716;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557	"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis"
FOCC004421-PA	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
FOCC013449-PA	4	MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
FOCC006692-PA	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
FOCC000161-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC012090-PA	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
FOCC012834-PA	1	MetaCyc: PWY-7511	"Protein ubiquitination"
FOCC005380-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC006166-PA	1	Reactome: R-HSA-8951664	"Neddylation"
FOCC003967-PA	9	Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6804756	"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation"
FOCC011541-PA	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
FOCC001433-PA	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
FOCC001529-PA	57	Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-2467813	"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Ub-specific processing proteases";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of DVL";"Asymmetric localization of PCP proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Neutrophil degranulation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids"
FOCC008981-PA	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
FOCC011533-PA	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
FOCC011060-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC003779-PA	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC011720-PA	14	MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs"
FOCC014999-PA	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
FOCC004905-PA	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
FOCC007703-PA	1	Reactome: R-HSA-912446	"Meiotic recombination"
FOCC012207-PA	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
FOCC000772-PA	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
FOCC001464-PA	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
FOCC001880-PA	1	Reactome: R-HSA-6798163	"Choline catabolism"
FOCC017948-PA	1	Reactome: R-HSA-70171	"Glycolysis"
FOCC015098-PA	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I"
FOCC013074-PA	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
FOCC004295-PA	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
FOCC013826-PA	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
FOCC016328-PA	57	Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-180534	"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neutrophil degranulation";"FCERI mediated NF-kB activation";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of AXIN";"Ub-specific processing proteases";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4"
FOCC000454-PA	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
FOCC014982-PA	5	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.21;Reactome: R-HSA-69205;KEGG: 00240+2.7.1.21;MetaCyc: PWY-7199	"Pyrimidine salvage";"Drug metabolism - other enzymes";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage"
FOCC007127-PA	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
FOCC015709-PA	5	Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination"
FOCC012043-PA	6	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
FOCC015947-PA	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
FOCC002994-PA	5	MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3	"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism"
FOCC013908-PA	15	Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)"
FOCC014879-PA	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
FOCC013554-PA	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
FOCC004425-PA	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
FOCC001109-PA	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
FOCC013359-PA	6	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
FOCC003941-PA	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
FOCC009296-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC002582-PA	7	Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-171319;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"UCH proteinases"
FOCC001527-PA	1	Reactome: R-HSA-3295583	"TRP channels"
FOCC004568-PA	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
FOCC016038-PA	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
FOCC000649-PA	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
FOCC015764-PA	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
FOCC004737-PA	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
FOCC001177-PA	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
FOCC004309-PA	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
FOCC016660-PA	19	Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038	"Chylomicron assembly";"LDL remodeling";"VLDL assembly";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"VLDL clearance";"Retinoid metabolism and transport";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"LDL clearance"
FOCC009314-PA	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
FOCC002730-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
FOCC010720-PA	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
FOCC000753-PA	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
FOCC003802-PA	6	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6787450;MetaCyc: PWY-7286	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
FOCC015355-PA	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
FOCC014881-PA	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
FOCC006859-PA	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
FOCC000065-PA	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
FOCC001619-PA	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
FOCC017988-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
FOCC008287-PA	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
FOCC003669-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC013748-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC006107-PB	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
FOCC004315-PA	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
FOCC001998-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC005642-PA	31	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693568;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-6804757;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-6803204;Reactome: R-HSA-69473;Reactome: R-HSA-8963888;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8866423;Reactome: R-HSA-6804760;Reactome: R-HSA-349425;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-6803207	"Human papillomavirus infection";"mTOR signaling pathway";"Stabilization of p53";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Relaxin signaling pathway";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Degradation";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"G2/M DNA damage checkpoint";"Chylomicron assembly";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"VLDL assembly";"Regulation of TP53 Activity through Methylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Thermogenesis";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Caspase Activators and Caspases"
FOCC011850-PA	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
FOCC002490-PA	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
FOCC006137-PA	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
FOCC001670-PA	1	Reactome: R-HSA-5617833	"Cilium Assembly"
FOCC005743-PA	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
FOCC004821-PA	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
FOCC017835-PA	19	Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-432142;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038	"VLDL assembly";"LDL remodeling";"Chylomicron assembly";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Platelet sensitization by LDL";"Post-translational protein phosphorylation";"VLDL clearance";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance"
FOCC015616-PA	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
FOCC003034-PA	5	Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
FOCC008064-PA	4	MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism"
FOCC003151-PA	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
FOCC005413-PA	6	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
FOCC015439-PA	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
FOCC005547-PA	1	Reactome: R-HSA-400253	"Circadian Clock"
FOCC010751-PA	14	MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-6453	"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis"
FOCC008313-PA	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
FOCC011254-PA	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
FOCC006879-PA	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
FOCC003092-PA	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
FOCC002549-PA	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
FOCC000022-PA	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
FOCC017762-PA	11	MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-381	"Ammonia assimilation cycle II";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)"
FOCC000124-PA	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"